CN1176702C

CN1176702C - Traditional Chinese medicine prepn. for treating Hepatitis

Info

Publication number: CN1176702C
Application number: CNB02127990XA
Authority: CN
Inventors: 何宗祥
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-12-06
Filing date: 2002-12-06
Publication date: 2004-11-24
Anticipated expiration: 2022-12-06
Also published as: CN1418661A

Abstract

The present invention relates to a traditional Chinese medicine preparation for treating hepatitis, which is prepared from floscule ovientvine and cape jasmine fruit. Compared with the prior art, the present invention has simple component, easy acquirement of medicinal materials as raw materials, simple production process, low cost of products, obvious curative effect of the medicine, conforms to the requirements for the national standard; the medicine has already obtained the production permit of the national medicine management department, and is named as 'a huazhi granule for removing heat from the liver'; the present invention has the effect on clearing away heat and promoting diuresis and dispersing the stagnated liver qi to promote bile flow, and is used for treating skin yellowing, poor appetite, hypochondriac pain, icterus, etc. caused by dampness and heat in the liver and gallbladder.

Description

The Chinese medicine preparation of treatment hepatitis

Technical field: the present invention is a kind of Chinese medicine preparation for the treatment of hepatitis, the Chinese medicine preparation that particularly utilizes Chinese herbal medicine to make.

Technical background: hepatitis is a kind of commonly encountered diseases, frequently-occurring disease, has a strong impact on the healthy of the mankind, and in China, its sickness rate of particularly vast rural area is that China classifies one of ten principal diseases that are detrimental to health greatly as than higher; This sick medicine of existing treatment is many, in the Western medicine curative effect reasonable be interferon and other medicines partner treatment, but its use cost is too high, the unable medical expense of bearing of general patient, many medicines appear in the Chinese medicine in recent years, can effectively treat hepatitis, but total sees, the therapeutic effect of these medicines is not desirable especially, importantly: the formation more complicated of these medicines, so, increased the patient burden owing to the many complex manufacturing of the raw medicinal material quantity of selecting for use, cost height.

Summary of the invention: the objective of the invention is to: a kind of Chinese medicine preparation for the treatment of hepatitis is provided; This medicine adopts the traditional national proved recipe of Guizhou minority nationality regions, on this basis, existing pharmaceutical production method is cooperated with it, the effect of drugs of making is obvious, low production cost, the patient can bear, and curative effect is relatively good, and the raw medicinal material of selecting for use in the medicine is easily got and is easy to get, and meets the provisions of the relevant regulations issued by the State; The present invention constitutes like this: according to weight proportion: mixed preparing formed after it extracted active ingredient by little cyanine Radix seu Caulis fici Martinii 1200-1350, Fructus Gardeniae 150-180 according to prior art; Specifically: it is prepared according to following method by little cyanine Radix seu Caulis fici Martinii 1333 grams, Fructus Gardeniae 167 grams: little cyanine Radix seu Caulis fici Martinii, Fructus Gardeniae are dropped into water decoction secondary, collecting decoction in the extraction equipment, filter, be concentrated into extractum, be made into the preparation that needs according to prior art then; More particularly: be that little cyanine Radix seu Caulis fici Martinii 1333 grams, Fructus Gardeniae 167 grams are dropped into water decoction secondary in the extraction pot, 3.5 hours first time, 1.5 hours for the second time, collecting decoction, filter, be concentrated into extractum, in the time of 80 degrees centigrade, its relative density is 1.07-1.12, adds an amount of powdered sugar spray granulation, granulate then, obtains granular preparation; Little cyanine Radix seu Caulis fici Martinii, Fructus Gardeniae can be adopted prior art according to given ratio among the present invention, as: alcohol extraction or super critical CO 2 technology extract, and the active substance that obtains is made into granule, tablet, capsule, ball, the oral liquid that needs according to prior art.

Compared with prior art: the present invention constitute fairly simple, raw medicinal material easily obtains, meet request of national standard, simultaneously production technology simple, make the with low cost of product, the curative effect of medicine is apparent in view, medicine has obtained the production certification of national drug administration section, trade name is " flower Cape jasmine liver heat removing granule ", and its clearing away heat-damp and promoting diuresis, depressed liver-energy dispersing and function of gallbladder promoting are used for the skin jaundice due to the dampness-heat in the liver and gallbladder, inappetence, treatment of conditions such as hypochondriac pain, jaundice; Oral, every day three times, each bag (granule: 1 bag, 12 grams); Among the present invention, be that monarch, Fructus Gardeniae are minister, play synergism, add white sugar and be assistant, play the seasoning effect liver protection effect of holding concurrently with little cyanine Radix seu Caulis fici Martinii; The slightly acid of little cyanine Radix seu Caulis fici Martinii medical material color green grass or young crops, feeble QI, flavor, be with sweet; Return through reaching theory of channels and collaterals, Radix Angelicae Sinensis liver, stomach, kidney channel by Chinese medicine; Conform to practical application experience; Fructus Gardeniae is as Chinese medicine, is generally acknowledged clearing away heat-damp and promoting diuresis, cures mainly the jaundice medicine; In the tradition proved recipe, custom is boiled into decoction with it, but the making of this dosage form does not have the art of composition, the poor stability of treatment, and mouthfeel is also poor especially, the patient is unwilling to take.

Embodiments of the invention 1: little cyanine Radix seu Caulis fici Martinii 1333 grams, Fructus Gardeniae 167 grams are dropped into water decoction secondary in the extraction pot, 3.5 hours first time, 1.5 hours for the second time, collecting decoction, filter, be concentrated into extractum, in the time of 80 degrees centigrade, its relative density is 1.07-1.12, adds an amount of powdered sugar spray granulation, granulate then, obtains granular preparation.

Embodiments of the invention 2: little cyanine Radix seu Caulis fici Martinii 1200 grams, Fructus Gardeniae 150 grams are dropped in the extraction pot and use the ethanol alcohol extraction,, be concentrated into extractum, add an amount of powdered sugar spray granulation, granulate then, obtain granular preparation with extracting solution.

Embodiments of the invention 3: utilize super critical CO 2 technology to extract little cyanine Radix seu Caulis fici Martinii 1350 grams, Fructus Gardeniae 180 grams, the extract that obtains is produced in flakes according to existing method again.

Embodiments of the invention 4: 400 kilograms of little cyanine Radix seu Caulis fici Martinii, Fructus Gardeniae are dropped into water decoction secondary in the extraction pot, 3.5 hours for the first time, 1.5 hours second time for 20 kilograms, collecting decoction, filter, be concentrated into extractum, in the time of 80 degrees centigrade, its relative density is 1.07-1.12, adds an amount of powdered sugar then and makes 10000 bag electuaries.

Claims

1, a kind of Chinese medicine preparation for the treatment of hepatitis is characterized in that: according to weight proportion: mixed preparing formed after it extracted active ingredient by little cyanine Radix seu Caulis fici Martinii 1200-1350, Fructus Gardeniae 150-180 according to prior art.

2, according to the Chinese medicine preparation of the described treatment hepatitis of claim 1, it is characterized in that: specifically: it is prepared according to following method by little cyanine Radix seu Caulis fici Martinii 1333 grams, Fructus Gardeniae 167 grams: little cyanine Radix seu Caulis fici Martinii, Fructus Gardeniae are dropped into water decoction secondary, collecting decoction in the extraction equipment, filter, be concentrated into extractum, be made into the preparation that needs according to prior art then.

3, according to the Chinese medicine preparation of claim 1 or 2 described treatment hepatitis, it is characterized in that: little cyanine Radix seu Caulis fici Martinii 1333 grams, Fructus Gardeniae 167 grams are dropped into water decoction secondary in the extraction pot, 3.5 hours first time, 1.5 hours for the second time, collecting decoction, filter, be concentrated into extractum, in the time of 80 degrees centigrade, its relative density is 1.07-1.12, add an amount of powdered sugar spray granulation, granulate then, obtain granular preparation.

4, according to the Chinese medicine preparation of claim 1 or 2 described treatment hepatitis, it is characterized in that: adopt alcohol extraction or super critical CO 2 technology to extract according to given ratio little cyanine Radix seu Caulis fici Martinii, Fructus Gardeniae, the active substance that obtains can be made into granule, tablet, capsule, ball, the oral liquid that needs according to prior art.