CN117664646A - Sampling control method, device, equipment, sample analyzer and medium - Google Patents
Sampling control method, device, equipment, sample analyzer and medium Download PDFInfo
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- 238000005070 sampling Methods 0.000 title claims abstract description 488
- 238000000034 method Methods 0.000 title claims abstract description 78
- 238000001514 detection method Methods 0.000 claims description 46
- 230000002159 abnormal effect Effects 0.000 claims description 23
- 238000004458 analytical method Methods 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 12
- 238000004590 computer program Methods 0.000 claims description 10
- 238000004140 cleaning Methods 0.000 claims description 7
- 239000000523 sample Substances 0.000 description 342
- 238000007599 discharging Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 8
- 230000000694 effects Effects 0.000 description 3
- 238000012423 maintenance Methods 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 230000001186 cumulative effect Effects 0.000 description 2
- 239000013074 reference sample Substances 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000013024 troubleshooting Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P90/00—Enabling technologies with a potential contribution to greenhouse gas [GHG] emissions mitigation
- Y02P90/02—Total factory control, e.g. smart factories, flexible manufacturing systems [FMS] or integrated manufacturing systems [IMS]
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Abstract
The application provides a sampling control method, a device, equipment, a sample analyzer and a medium book, wherein the sampling control method comprises the following steps: in the process of controlling a sampling needle to execute a current sub-sampling task, after the sampling needle is controlled to execute a sample sucking action, determining whether the current sample sucking quantity of the sampling needle is a normal sample sucking quantity according to a post-sample sucking characteristic value of a characteristic parameter of the sampling needle, when the sample sucking quantity of the sampling needle is determined to be the normal sample sucking quantity, controlling the sampling needle to move out of a sample container, and moving the sampling needle to a sample dripping position for sample dripping, wherein the current sub-sampling task is completed, otherwise, controlling the sampling needle to execute a sample spitting action, and after the sampling needle is executed, controlling the sampling needle to return to execute the sample sucking action, namely re-executing the sample sucking action in the current sub-sampling task. Therefore, the sampling control method can improve the accuracy of sample suction and reduce the equipment overhaul time.
Description
Technical Field
The application relates to the technical field of medical instruments, in particular to a sampling control method, a sampling control device, a sampling control equipment, a sample analyzer and a sampling control medium.
Background
In an in vitro diagnostic instrument, the accuracy of the sampling amount has a crucial influence on the performance of the instrument, and the accuracy directly influences whether the performance of the instrument can meet the index requirements. Many factors influencing the sampling accuracy are involved, such as the situation that the sampling needle encounters empty suction, bubbles, floccules, clots and the like in the sampling process, which can cause abnormal sampling of the system.
In the existing sampling control process, when detecting equipment detects abnormal sampling of a sampling needle, sampling is stopped and fault prompt is carried out every time, and sampling can be continued again only after workers need to carry out fault detection, so that the sampling efficiency is low.
Disclosure of Invention
In order to solve the existing technical problems, the application provides a sampling control method, a device and equipment with high sample suction accuracy, a sample analyzer and a medium, wherein the sampling control method, the device and the equipment can reduce the overhaul time of sampling equipment.
A sampling control method, comprising:
in the process of controlling the sampling needle to execute the current sampling task, after the sampling needle completes the sampling action, acquiring a post-sampling characteristic value of a characteristic parameter of the sampling needle, wherein the characteristic parameter is a parameter related to the sampling amount of the sampling needle;
determining whether the sample suction amount of the sampling needle is a normal sample suction amount according to the characteristic value after the sample suction;
if yes, the sampling needle is controlled to move out of the sample container, and the sampling needle is moved to a sample dripping position to drip samples, so that the current sampling task is completed;
if not, controlling the sampling needle to execute the sample ejection action, and controlling the sampling needle to return to execute the sample suction action after the sampling needle executes the sample ejection action.
A sampling control device, comprising:
the determining module is used for determining whether the sample sucking quantity of the sampling needle is a normal sample sucking quantity after the sampling needle finishes the current sample sucking action;
the first control module is used for controlling the sampling needle to move out of the sample container and moving the sampling needle to a sample dripping position for sample dripping when determining whether the sample sucking amount of the sampling needle is the normal sample sucking amount;
and the second control module is used for controlling the sampling needle to execute a sample-spitting action when determining whether the sample suction amount of the sampling needle is the normal sample suction amount or not, and controlling the sampling needle to return to execute the sample suction action after the sampling needle executes the sample-spitting action.
A sampling device comprising a processor and a memory, wherein a computer program executable by the processor is stored in the memory, which computer program, when executed by the processor, implements the sampling control method as described.
A sampling device comprises a sampling controller, a sampling needle and a sample suction detection component, wherein the sampling controller is used for realizing the sampling control method;
the sample suction detection component is respectively connected with the sampling controller and the sampling needle and is used for detecting the characteristic parameters of the sampling needle after the sampling needle finishes the current sample suction action to obtain the characteristic value after the sample suction, and sending the characteristic value after the sample suction to the sampling controller.
The sample analyzer comprises a detection analysis device and the sampling equipment, wherein the detection analysis device performs detection analysis according to a sample to be detected acquired by the sampling equipment to obtain detection analysis data of the sample to be detected.
A computer readable storage medium having stored thereon a computer program which, when executed by a control device, implements a sampling control method as described.
In view of the above, in the sampling control method provided by the present application, in the process of controlling the sampling needle to execute the current sub-sampling task, after the sampling needle is controlled to execute the sample sucking action, whether the current sample sucking amount of the sampling needle is the normal sample sucking amount is determined according to the post-sample sucking characteristic value of the characteristic parameter of the sampling needle, when the sample sucking amount of the sampling needle is determined to be the normal sample sucking amount, the sampling needle is controlled to be moved out of the sample container, and the sampling needle is moved to a sample dropping position for sample dropping, and if not, the sampling needle is controlled to execute the sample spitting action, and after the sampling needle is controlled to execute the sample spitting action, the sampling needle is controlled to return to execute the sample sucking action, namely, the sample sucking action in the current sub-sampling task is re-executed. Therefore, the sampling control method can improve the accuracy of sample suction and reduce the equipment overhaul time.
Drawings
Fig. 1 is a flow chart of a sampling control method according to an embodiment of the present application;
FIG. 2 is a flow chart of a sample control method according to another embodiment of the present application;
fig. 3 is a schematic diagram of the sampling process of the sampling needle in the sampling control method according to the embodiment of the present application;
FIG. 4 is a flow chart of a sampling control method according to further embodiments of the present application;
FIG. 5 is a schematic diagram of a sampling control device according to some embodiments of the present application;
fig. 6 is a schematic structural diagram of a sampling device according to an embodiment of the present application;
FIG. 7 is a schematic diagram of a sampling device according to other embodiments of the present application;
fig. 8 is a flowchart of a method for performing a sampling task by a sampling device according to an embodiment of the present application.
Detailed Description
The technical scheme of the application is further elaborated below by referring to the drawings in the specification and the specific embodiments.
For the purpose of making the objects, technical solutions and advantages of the present application more apparent, the present application will be described in further detail with reference to the accompanying drawings, and the described embodiments should not be construed as limiting the present application, and all other embodiments obtained by those skilled in the art without making any inventive effort are within the scope of the present application.
In the following description, reference is made to the expression "some embodiments" which describe a subset of all possible embodiments, it being noted that "some embodiments" may be the same subset or different subsets of all possible embodiments and may be combined with each other without conflict.
In the following description, the terms "first, second, third" and the like are used merely to distinguish between similar objects and do not represent a specific ordering of the objects, it being understood that the "first, second, third" may be interchanged with a specific order or sequence, as permitted, to enable embodiments of the application described herein to be practiced otherwise than as illustrated or described herein.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing embodiments of the present application only and is not intended to be limiting of the present application.
Fig. 1 is a schematic flow chart of a sampling control method according to an embodiment of the present application. The sampling control method provided by the embodiment of the application can be applied to a sample analyzer. And the sample analyzer samples and detects the sample to be detected by using the sampling control method to obtain a sample detection result corresponding to the sample to be detected. The sample analyzer may be a blood cell analyzer, an immunoassay analyzer, a biochemical analyzer, or the like. In some embodiments, the sampling control method may also be applied to a sampling device, where the sampling device samples a sample to be tested according to the sampling control method for detection by a sample analyzer. The sample analyzer and the sampling device to which the sampling control method provided in the embodiments of the present application are applied will be described in detail later. The sampling control method provided in this embodiment includes steps S02, S04, S06, and S08, which are described in detail below.
S02: and in the process of controlling the sampling needle to execute the current sampling task, after the sampling needle completes the sampling action, acquiring a post-sampling characteristic value of a characteristic parameter of the sampling needle, wherein the characteristic parameter is a parameter related to the sampling amount of the sampling needle.
When the sample analyzer detects and analyzes a sample to be detected, sampling operation is required to be performed on the sample to be detected by utilizing sampling. The sample to be tested includes, but is not limited to, blood, urine or sweat, and tissue fluid of the object to be tested. When the sample analyzer detects a sample to be measured, it may be necessary to control the sampling to perform multiple sampling tasks. Controlling the sampling needle each time the sampling task includes: the sampling needle is controlled to move from an initial position to a first direction, so that after the needle head of the sampling needle pierces a container cap of the sample container, the sampling needle is continuously moved to a sample suction position below the liquid level of a sample to be tested, a sample suction action is executed at the sample suction position, after the sample suction action is finished, the sampling needle is controlled to move towards a second direction opposite to the first direction, the sampling needle is pulled out of the sample container and then moved to a sample dropping position for sample dropping, and after sample dropping is finished, the sampling needle is controlled to return to the initial position. If the sampling needle still needs to execute the next sampling task after completing the execution of the current sampling task, the sampling needle is continuously controlled to continuously execute the next sampling task according to the flow.
One end of the sampling needle is a needle end, and the other end of the sampling needle is connected with a power source through a sampling pipeline. The sampling pipeline is used for transmitting the power output by the power source to the sampling needle. The power source comprises a pneumatic pump or an injector for outputting positive and negative air pressure into the sampling needle, and a motor for driving the sampling needle to move. By controlling the motor, the sampling needle can be made to move at a set timing.
The characteristic parameter of the sampling needle is related to the sample suction amount of the sampling needle, namely the characteristic parameter refers to the characteristic parameter which can characterize the current sample suction amount in the sampling needle, and the characteristic value of the characteristic parameter changes along with the current sample suction amount of the sampling needle. The characteristic parameter is the pressure in the sampling needle, the page height of the sample to be tested in the sampling needle, or the particle number of the sample to be tested in the sampling needle. The characteristic value after the sample is sucked is a value of the characteristic parameter of the sampling needle after the sampling needle executes the sample sucking action, namely, the value of the characteristic parameter of the sampling needle when the sampling needle has the sucked sample to be tested after the sampling needle executes the sample sucking action.
S04: and determining whether the sample sucking quantity of the sampling needle is a normal sample sucking quantity according to the characteristic value after the sample sucking.
Because the characteristic parameter of the sampling needle is related to the sample suction amount of the sampling needle, the current sample suction amount information of the sampling needle can be obtained according to the characteristic value after the sample suction by obtaining the characteristic value after the sample suction, so as to determine whether the sample suction amount of the sampling needle meets the set sample suction amount, if yes, the normal sample suction amount of the sample suction amount position of the sampling needle is indicated, and further the current sample suction action is indicated as the normal sample suction action, so that the current sub-sampling task can be continuously executed according to the normal flow, namely, when the sample suction amount is determined to be the normal sample suction, S06 is executed, otherwise, the current sample suction amount is indicated as the abnormal sample suction amount, and S08 is executed.
S06: when the sample sucking quantity of the sampling needle is the normal sample sucking quantity, the sampling needle is controlled to move out of the sample container, and the sampling needle is moved to a sample dropping position to drop samples, so that the current sub-sampling task is completed.
When the current sample suction amount of the sampling needle is the normal sample suction amount, the sample suction action currently executed by the sampling needle is considered to be an effective sample suction action, and then the sample to be tested, which is the normal sample suction amount, in the sampling needle can be conveyed to a sample dropping position for sample dropping. Specifically, the sampling needle is controlled to move along the second direction, so that the sampling needle is pulled out of the sample container, and then the sampling needle is controlled to move to a sample dropping position according to a preset moving track to drop samples. In some embodiments, the drop sample position may also be a detection position of a sample analyzer, after the sampling needle drops the sucked sample to be detected at the detection position, a detection component in the sample analyzer performs detection analysis on the sample to be detected at the detection position, so as to obtain a corresponding detection analysis result.
S08: when the sample sucking amount of the sampling needle is abnormal, the sampling needle is controlled to execute the sample spitting action, and after the sampling needle executes the sample spitting action, the sampling needle is controlled to return to execute the sample sucking action.
When the current sample suction amount of the sampling needle is an abnormal sample suction amount, if the to-be-detected sample of the abnormal sample suction amount is continuously moved to the sample dropping position for sample dropping, the to-be-detected sample amount detected by the sample analyzer does not meet the detection requirement, and the result of sample analysis may be inaccurate. According to the method in the prior art, when the sample suction amount of the sampling needle is found to be abnormal, the current sub-sampling task is stopped, fault information is reported, corresponding fault troubleshooting is carried out by maintenance personnel, and the sampling needle is controlled to execute the current sub-sampling task again until the fault is eliminated. However, in the sampling control method provided in the embodiment of the present application, when the sample suction amount of the sampling needle is abnormal, the sample suction action currently executed by the sampling needle is considered to be an ineffective sample suction action, the sampling needle is controlled to execute a sample ejection action, and after the sample ejection action is executed, the sample suction action of the current sampling task is executed again. By executing the sample-spitting action after abnormal sample suction, the abnormal sample to be detected sucked into the sampling needle can be discharged into the sample container, and the sample suction action is re-executed, so that the abnormal sample to be detected can be moved to the sample-dropping position for sample dropping only when the sample suction amount is the normal sample suction amount. Because abnormal sample suction sometimes is not caused by faults of sampling equipment, in the prior art, fault alarm is carried out when sample suction abnormality is detected every time, the overhaul frequency and time of the equipment can be increased, the labor cost is increased, and meanwhile, the detection efficiency of a sample analyzer is not improved. In the sample control method provided by the embodiment of the application, when abnormal sample suction is determined, the sampling needle is controlled to execute the sample-spitting action so as to discharge the sucked foreign matters, then the sample suction action is executed again, and the sample suction quantity of the sampling needle is possibly the normal sample suction quantity after the sample suction action is executed again, so that the maintenance frequency is effectively reduced, the time cost of maintenance personnel is reduced, and the sample suction accuracy is also improved.
From the above, in the sampling control method provided in the embodiment of the present application, in the process of controlling the sampling needle to execute the current sub-sampling task, after the sampling needle is controlled to execute the sample sucking action, whether the current sample sucking amount of the sampling needle is a normal sample sucking amount is determined according to the post-sample sucking characteristic value of the characteristic parameter of the sampling needle, when the sample sucking amount of the sampling needle is determined to be the normal sample sucking amount, the sampling needle is controlled to be moved out of the sample container, and the sampling needle is moved to a sample dropping position for sample dropping, so as to complete the current sub-sampling task, otherwise, the sampling needle is controlled to execute the sample discharging action, and after the sampling needle is controlled to execute the sample discharging action, the sampling needle is controlled to return to execute the sample sucking action, i.e. the sample sucking action in the current sub-sampling task is re-executed. Therefore, the sampling control method can improve the accuracy of sample suction and reduce the equipment overhaul time.
Fig. 2 is a flowchart illustrating a sample control method according to another embodiment of the present application. In this embodiment, S04 may specifically include S041, S02, S06, and S08 are the same as the above description, and will not be described here. S041 is specifically described below.
S041: and determining whether the sample suction amount of the sampling needle is abnormal sample suction amount according to the difference between the characteristic value after the sample suction and the characteristic value before the sample suction, wherein the characteristic value before the sample suction is the value corresponding to the characteristic parameter before the sampling needle executes the current sample suction action.
The characteristic value before the sample suction is a value corresponding to the characteristic parameter of the sampling needle before the sampling needle executes the sample suction action. The difference between the characteristic value after the sample is sucked and the characteristic value before the sample is sucked refers to the change value of the characteristic parameter of the sample sucking needle before and after the sample is sucked. For example, the difference value calculation can be performed on the characteristic value after sample suction and the characteristic value after sample suction to obtain a corresponding difference value result, then the sample suction amount in the sampling needle is determined according to the difference value result, then the sample suction amount in the sampling needle is compared with the reference sample suction amount corresponding to the current sampling task, if the error between the sample suction amount in the sampling needle and the reference sample suction amount is within the allowable error range, the current sample suction amount of the sampling needle is the normal sample suction amount, otherwise, the sample suction amount of the sampling needle is the abnormal sample suction amount.
Further, in some embodiments, before executing S041, the sampling control method further comprises: before the sampling needle is controlled to execute the sample sucking action, the characteristic parameters in the sampling needle are obtained, and the characteristic values before the sample sucking corresponding to the characteristic parameters are obtained. The characteristic value before suction is a value preset by sampling equipment for realizing the sampling control method, or a value obtained by detecting the characteristic parameter by a sampling amount detecting part before the sampling needle executes the suction operation.
In some embodiments, the characteristic parameter in the sampling control method is pressure in the sampling needle, and the characteristic value after sample suction is a pressure value of the sampling needle when the sampling needle executes a sample suction action and a current sample to be tested of a sample suction amount is in the sampling needle. The characteristic value before the sample suction is a pressure value when the sample to be detected is not contained in the sampling needle before the sample suction is executed. Specifically, after the sampling needle completes the sample sucking action, the pressure in the sampling needle is detected by controlling the pressure detection component to obtain a corresponding pressure value, namely the characteristic value after sample sucking is obtained. Such as a pressure sensor or the like. The pressure detecting means may directly detect the pressure value in the sampling needle, or may detect the pressure value in the sampling line communicating with the sampling needle as the pressure value in the sampling needle. Because the sampling needle is in communication with the sampling line, the pressure value within the sampling needle and the pressure value within the sampling line may be considered equal or relatively close.
In some embodiments, the characteristic parameter in the sampling control method is a liquid level of the sample to be measured in the sampling needle, and the characteristic value after the sample is sucked is the liquid level of the sample to be measured in the sampling needle after the sample sucking operation is performed. The characteristic value before suction is the liquid level of the sample to be detected in the sampling needle before executing the suction, and the liquid level to be detected in the sampling needle before executing the suction can be considered to be zero because the sampling needle has no sample to be detected in the sampling needle before executing the suction. After the sampling needle completes the sample sucking action, the liquid level detection part can be controlled to obtain the liquid level of the sample to be detected in the sample sucking needle. The liquid level detection component can be an optical coupler arranged above the sampling needle, and the height of the sample to be detected in the sampling needle is obtained by acquiring the sensing information of the optical coupler.
Further, in some embodiments, in S08: the step of controlling the sampling needle to execute the sample spitting action specifically comprises the following steps: and controlling a power source communicated with the sampling needle to output positive air pressure to the sampling needle, so that the pressure in the sampling needle is in a positive air pressure state, and the sample to be detected sucked by the sampling needle is discharged into the sample container.
The positive pressure refers to a pressure higher than the first atmospheric pressure, and the subsequent negative pressure refers to a pressure lower than one atmospheric pressure. The air pressure in the sample to be detected in the sample container can be regarded as one atmosphere, when the sampling needle is in a negative air pressure state, namely, when the air pressure in the sampling needle is in a negative air pressure state, the air pressure in the sampling needle is lower than the air pressure in the sample to be detected in the sample container, the sample to be detected is sucked into the sampling needle under the action of air pressure difference, and the sampling needle completes the sample suction action. The sample sucking action of the sampling needle refers to the action that the sampling needle sucks the sample to be tested at a sample sucking position. When the sampling needle is in a positive air pressure state, namely when the air pressure in the sampling needle is positive air pressure, the air pressure in the sampling needle is higher than the air pressure in a sample to be tested of the sample container, so that the sample to be tested in the sampling needle is discharged from the sampling needle under the action of air pressure difference, namely the sampling needle spits back into the sample container, and the sampling needle finishes a sample spitting action. The sample ejection action of the sampling needle refers to the action of the sampling needle in ejecting the sample to be tested into the sample container at the current sample suction position.
In some embodiments, the sampling control method further comprises: and in the process of controlling the sampling needle to move towards the current suction position, controlling the pressure in the sampling needle to be in a negative air pressure state before the needle head of the sampling needle moves into the sample to be tested of the sample container. As shown in fig. 3, a schematic diagram of a sampling needle suction process is shown. Because the air pressure in the sampling needle is negative before the sampling needle enters the sample to be tested in the sample container, the air pressure in the sampling needle is smaller than the first air pressure in the period from the time when the air pressure in the sampling needle is changed to the negative air pressure to the time when the sampling needle moves to the sample suction position, a small section of air is sucked into the sampling needle before the sampling needle sucks the sample to be tested, and the sample to be tested sucked into the sampling needle is isolated from the pipeline liquid in the sample suction pipeline through the small section of air, so that the influence of the pipeline liquid on the sample suction accuracy of the sampling needle is avoided.
Further, the controlling the sampling needle to execute the sample spitting action specifically includes: and controlling a power source for providing power for the sampling needle to provide positive air pressure with a preset value for the sampling needle, so that the sampling needle can discharge all the sucked samples to be tested, and the small section of air in the sampling pipeline cannot be discharged into the sample container.
In some embodiments, in S08: after the sample spitting action is finished, controlling the sampling needle to return to execute the sample sucking action, which specifically comprises the following steps: after the sample spitting action is finished, the sampling needle is controlled to move from the current position to a preset sample sucking position, and then the sample sucking action is executed. In this embodiment, after the sample-discharging operation is performed by the sampling needle, the current position of the sampling needle after the sample-discharging operation is performed is not controlled to directly perform the sample-sucking operation, but the sampling needle is controlled to be moved from the current position to a preset sample-sucking position before performing the sample-sucking operation. Therefore, the sampling needle can be prevented from executing the sample sucking action again in the area where the original sample sucking position where the sample clot or the fragments possibly exist, and the abnormal sample sucking amount is sucked again.
In some embodiments, the controlling the sampling needle to move from the current position to the preset sample sucking position specifically includes controlling the sampling needle to move to the preset sample sucking position along the first direction, that is, the preset sample sucking position is located below the current position.
In some embodiments, the controlling the sampling needle to move from the current position to the preset sample sucking position specifically includes controlling the sampling needle to move to the preset sample sucking position along the second direction, that is, the preset sample sucking position is located above the current position.
In some embodiments, the controlling the sampling needle to move from the current position to the preset sample sucking position specifically includes controlling the sampling needle to move to the preset sample sucking position along the third direction perpendicular to the first direction, that is, the preset sample sucking position is located at the left side of the current position.
In some embodiments, the controlling the sampling needle to move from the current position to the preset sample sucking position specifically includes controlling the sampling needle to move to the preset sample sucking position along the fourth direction opposite to the third direction, that is, the preset sample sucking position is located on the right side of the current position.
Fig. 4 is a flowchart illustrating a sampling control method according to still other embodiments of the present application. In the present embodiment, after S08, S09 is further included.
S09: and judging the accumulated times of the sample sucking action performed by the sampling needle, and if the sample sucking quantity of the sampling needle is still abnormal and the accumulated times reach a threshold value, reporting fault alarm information.
Generally, after the accumulated times reach 2 times, if the sample suction amount of the sampling needle is still determined to be the abnormal sample suction amount, the current high probability is that the sampling equipment has a storage fault, and fault alarm information is reported to remind the overhauling personnel of overhauling. In other embodiments, the sampling control method further includes controlling a cleaning device to perform a cleaning process on the sampling needle according to the fault alarm information, and controlling the sampling needle to perform a sampling task after the cleaning process is completed.
Fig. 5 is a schematic structural diagram of a sampling control device according to some embodiments of the present application. In this embodiment, the sampling control device includes a determining module 501, a first control module 502, and a second control module 503. The determining module 501 is configured to determine whether the sample sucking amount of the sampling needle is a normal sample sucking amount after the sampling needle completes the current sample sucking operation. The first control module 502 is configured to control the sampling needle to move out of the sample container and move the sampling needle to a sample dripping position for sample dripping when determining whether the sample sucking amount of the sampling needle is a normal sample sucking amount. The second control module 503 is configured to control the sampling needle to perform a sample ejection action when determining whether the sample suction amount of the sampling needle is a normal sample suction amount, and control the sampling needle to return to perform the sample suction action after the sampling needle performs the sample ejection action. The sample control device and the sample control method provided in the foregoing embodiments can achieve the same technical effects, and in order to avoid repetition, a detailed description is omitted here.
In some embodiments, the sampling control device further includes an alarm control module (not shown in fig. 5), where the alarm control module is configured to determine a cumulative number of times the sampling needle has performed the sample sucking action, and if it is determined that the sample sucking amount of the sampling needle is still an abnormal sample sucking amount and the cumulative number of times reaches a threshold value, report fault alarm information.
Fig. 6 is a schematic structural diagram of a sampling device according to an embodiment of the present application. In this embodiment, the sampling device includes a processor 61 and a memory 62, where the memory 62 stores a computer program executable by the processor, and the computer program implements the sampling control method according to any one of the embodiments of the present application when executed by the processor, so that the sampling device and the sampling control method provided in the foregoing embodiment can achieve the same technical effects, and are not repeated here.
Fig. 7 is a schematic structural diagram of a sampling apparatus according to another embodiment of the present application, where the sampling apparatus is used for sampling a sample to be measured in a sample container 5. The sampling device comprises a sampling controller (not shown in fig. 7) for implementing the sampling control method according to any embodiment of the present application, a sampling needle 1 and a suction detection part 2. The sample suction detection component 2 is respectively connected with the sampling controller and the sampling needle 1, and is used for detecting the characteristic parameters of the sampling needle after the sampling needle 1 finishes the current sample suction action, obtaining the characteristic value after sample suction, and sending the characteristic value after sample suction to the sampling controller.
With continued reference to fig. 7, in some embodiments, the sampling device further includes a sampling line 3 and a power source 4. The sampling needle 1 is communicated with the power source 4 through the sampling pipeline 3, and the sample suction detection component 2 is arranged on the sampling pipeline 3 so as to be connected with the sampling needle 1 through the sampling pipeline 3. The power source 4 is connected with the sampling controller, and is used for conveying negative air pressure to the sampling needle 1 through the sampling pipeline 3 when the sampling needle 1 needs to execute a sample sucking action according to the control of the sampling controller, and conveying positive air pressure to the sampling needle through the sampling pipe 3 when the sampling needle 1 needs to execute a sample spitting action.
In some embodiments, the sample detection member 2 is a pressure detection member, such as a pressure sensor.
In some embodiments, the sample detection means 2 is a detection means, such as an optocoupler arranged above the sample container 5.
Fig. 8 is a flowchart of a method for performing a sampling task by a sampling device according to an embodiment of the present application. The sampling device firstly executes a first sample sucking action on a sample to be detected in the sample container, and then performs sample sucking quantity detection so as to determine whether the sample sucking quantity of the sampling needle after executing the first sample sucking action is normal or not. If the first sample suction amount of the sampling needle is determined to be the normal sample suction amount, the sampling equipment executes the current sampling task according to the normal flow. If the first sample sucking amount is determined to be the abnormal sample sucking amount, the sampling needle executes the sample discharging action, and after the sample discharging is completed, the sampling needle executes the secondary sample sucking action, namely, the sampling needle returns to execute the sample sucking action. After the secondary sample suction action of the sampling needle is finished, the sample suction amount of the secondary sample suction of the sampling needle is continuously checked, and if the sample suction amount of the secondary sample suction of the sampling needle is determined to be the normal sample suction amount, the sampling equipment executes the current sampling task according to the normal flow. If the sample suction amount of the secondary sample suction of the sampling needle is still abnormal, the system where the sampling equipment is located alarms, and a cleaning device in the system executes a cleaning flow for the sampling needle.
The sample analyzer comprises a detection analysis device and the sampling equipment, wherein the detection analysis device performs detection analysis according to a sample to be detected acquired by the sampling equipment to obtain detection analysis data of the sample to be detected.
A computer readable storage medium having stored thereon a computer program which, when executed by a control device, implements a sampling control method as described.
From the above, in the sampling device provided by the application, after the sampling needle performs the sample sucking action in the process of performing the current sampling task, determining whether the current sample sucking amount of the sampling needle is a normal sample sucking amount according to the post-sample sucking characteristic value of the characteristic parameter of the sampling needle, when the sample sucking amount of the sampling needle is determined to be the normal sample sucking amount, moving the sampling needle out of the sample container and to a sample dropping position for sample dropping, and performing the sample discharging action according to the current sampling task, otherwise, performing the sample discharging action by the sampling needle, and after the sampling needle performs the sample discharging action, returning to perform the sample sucking action, namely re-performing the sample sucking action in the current sampling task. Therefore, the sampling device has higher accuracy of sample suction, and meanwhile, the equipment overhaul time can be reduced.
In addition, in some embodiments, the application further provides a sample analyzer, where the sample analyzer includes the sampling device and a detection analysis device connected to the sampling device according to any embodiment of the application, and the detection analysis device performs detection analysis according to a sample to be detected collected by the sampling device, so as to obtain detection analysis data of the sample to be detected.
The embodiment of the application further provides a computer readable storage medium, on which a computer program is stored, which when executed by a processor, implements each process of the above embodiment of the sampling control method, and can achieve the same technical effects, so that repetition is avoided, and no further description is provided herein. The computer readable storage medium is, for example, read-only memory (ROM), random Access Memory (RAM), magnetic disk or optical disk.
The foregoing is merely specific embodiments of the present application, but the scope of the present application is not limited thereto, and any person skilled in the art can easily think about changes or substitutions within the technical scope of the present application, and the changes and substitutions are intended to be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.
Claims (17)
1. A sampling control method, comprising:
in the process of controlling the sampling needle to execute the current sampling task, after the sampling needle completes the sampling action, acquiring a post-sampling characteristic value of a characteristic parameter of the sampling needle, wherein the characteristic parameter is a parameter related to the sampling amount of the sampling needle;
determining whether the sample suction amount of the sampling needle is a normal sample suction amount according to the characteristic value after the sample suction;
if yes, the sampling needle is controlled to move out of the sample container, and the sampling needle is moved to a sample dripping position to drip samples, so that the current sampling task is completed;
if not, controlling the sampling needle to execute the sample ejection action, and controlling the sampling needle to return to execute the sample suction action after the sampling needle executes the sample ejection action.
2. The sampling control method according to claim 1, wherein the determining whether the sampling amount of the sampling needle is a normal sampling amount according to the post-sampling characteristic value includes:
and determining whether the sample suction amount of the sampling needle is abnormal sample suction amount according to the difference between the characteristic value after the sample suction and the characteristic value before the sample suction, wherein the characteristic value before the sample suction is the value corresponding to the characteristic parameter before the sampling needle executes the current sample suction action.
3. The sampling control method according to claim 2, wherein before said determining whether the sampling amount of the sampling needle is a normal sampling amount, the method further comprises:
before the sampling needle is controlled to execute the sample sucking action, the characteristic parameters in the sampling needle are obtained, and the characteristic values before the sample sucking corresponding to the characteristic parameters are obtained.
4. The sampling control method according to claim 2, wherein the characteristic parameter is a pressure in the sampling needle.
5. The sampling control method according to claim 2, wherein the characteristic parameter is a liquid level height of a sample to be measured in the sampling needle.
6. The sampling control method according to claim 1, wherein the controlling the sampling needle to perform a spitting action comprises:
and controlling a power source communicated with the sampling needle to output positive air pressure to the sampling needle, so that the pressure in the sampling needle is in a positive air pressure state, and the sample to be detected sucked by the sampling needle is discharged into the sample container.
7. The sampling control method according to claim 1, further comprising:
and in the process of controlling the sampling needle to move towards the current suction position, controlling the pressure in the sampling needle to be in a negative air pressure state before the needle head of the sampling needle moves into the sample to be tested of the sample container.
8. The sampling control method according to claim 1, wherein after the control of the sampling needle to return to performing the sample sucking action, the sampling control method further comprises:
and judging the accumulated times of the sample sucking action performed by the sampling needle, and if the sample sucking quantity of the sampling needle is still abnormal and the accumulated times reach a threshold value, reporting fault alarm information.
9. The sampling control method according to claim 8, further comprising:
and controlling the cleaning device to execute a cleaning process on the sampling needle according to the fault alarm information.
10. The method according to claim 1, wherein controlling the sampling needle to return to executing the sample sucking operation after the sample sucking operation is completed, comprises:
after the sample spitting action is finished, the sampling needle is controlled to move from the current position to a preset sample sucking position, and then the sample sucking action is executed.
11. A sampling control device, comprising:
the determining module is used for determining whether the sample sucking quantity of the sampling needle is a normal sample sucking quantity after the sampling needle finishes the current sample sucking action;
the first control module is used for controlling the sampling needle to move out of the sample container and moving the sampling needle to a sample dripping position for sample dripping when determining whether the sample sucking amount of the sampling needle is the normal sample sucking amount;
and the second control module is used for controlling the sampling needle to execute a sample-spitting action when determining whether the sample suction amount of the sampling needle is the normal sample suction amount or not, and controlling the sampling needle to return to execute the sample suction action after the sampling needle executes the sample-spitting action.
12. A sampling device comprising a processor and a memory, wherein the memory stores a computer program executable by the processor, the computer program implementing the sampling control method according to any one of claims 1 to 10 when executed by the processor.
13. A sampling apparatus comprising a sampling controller for implementing the sampling control method according to any one of claims 1 to 10, a sampling needle, and a suction detection means;
the sample suction detection component is respectively connected with the sampling controller and the sampling needle and is used for detecting the characteristic parameters of the sampling needle after the sampling needle finishes the current sample suction action to obtain the characteristic value after the sample suction, and sending the characteristic value after the sample suction to the sampling controller.
14. The sampling device of claim 13, further comprising a sampling line and a power source;
the sampling needle is communicated with the power source through the sampling pipeline, and the sample suction detection component is arranged on the sampling pipeline and is connected with the sampling needle through the sampling pipeline;
the power source is connected with the sampling controller and is used for conveying negative air pressure to the sampling needle through the sampling pipeline when the sampling needle needs to execute a sample sucking action according to the control of the sampling controller, and conveying positive air pressure to the sampling needle through the sampling pipeline when the sampling needle needs to execute a sample spitting action.
15. The sampling device of claim 13, wherein the suction detection component is a pressure detection component or a liquid level detection component.
16. A sample analyzer comprising a detection and analysis device and the sampling apparatus according to any one of claims 12 to 15, wherein the detection and analysis device performs detection and analysis on a sample to be measured collected by the sampling apparatus, and obtains detection and analysis data of the sample to be measured.
17. A computer-readable storage medium, characterized in that the computer-readable storage medium has stored thereon a computer program which, when executed by a control apparatus, implements the sampling control method according to any one of claims 1 to 10.
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| CN202211004422.7A CN117664646A (en) | 2022-08-22 | 2022-08-22 | Sampling control method, device, equipment, sample analyzer and medium |
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| CN202211004422.7A CN117664646A (en) | 2022-08-22 | 2022-08-22 | Sampling control method, device, equipment, sample analyzer and medium |
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| CN202211004422.7A Pending CN117664646A (en) | 2022-08-22 | 2022-08-22 | Sampling control method, device, equipment, sample analyzer and medium |
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