CN117538128B - Pathology department's sample section dyeing equipment - Google Patents

Abstract

The invention discloses a specimen slice dyeing device of a pathology department, and particularly relates to the field of slice dyeing, comprising a machine case and a slide frame, wherein the slide frame is used for installing a plurality of slides with specimen slices, a plurality of dye vats are arranged in the machine case, a mechanical arm is also arranged in the machine case, and the mechanical arm is used for conveying the slide frame into the dye vats to dye the specimen slices on the slides; at least one holding assembly is mounted on the slide mount; the holding component comprises a supporting frame, the supporting frame is used for clamping the glass slide, and a fixing frame is arranged below the supporting frame. The invention can prevent the broken tissue formed by the water swelling and cracking of the sample tissue from entering the dye vat to pollute the dye liquor, can control the dye liquor to enter the inner cavity to dye the sample slice, and can make the sample slice contact with the solution at a higher speed under the combined action of the double dyeing of the external dye liquor and the contact of the sample slice through the filter paper, thereby improving the dyeing and soaking efficiency and shortening the dyeing time.

Description

Pathology department's sample section dyeing equipment

Technical Field

The invention relates to the technical field of slice staining, in particular to a specimen slice staining device for a pathology department.

Background

Staining is the simplest and effective method for observing cells, and by means of staining, cells can be stained, and the staining can be clearly compared with visual field background, so that tissue structures can be observed more clearly; among them, HE staining (hematoxylin-eosin staining) is one of the most commonly used staining methods for pathological sections.

The existing HE dyeing machine is internally provided with tens of dye vats, each dye vat is respectively filled with different solutions, and when in dyeing, a mechanical arm in the dyeing machine is used for grabbing a slide frame until the dye vats are immersed for dyeing, and the dyeing solution can be reused for a plurality of times. Specifically, when the pathological tissue section is dyed, the pathological tissue section is soaked in the dye vat for a certain time, so that the dye liquor can invade between the pathological tissue section and the bonding surface of the glass slide, and the pathological tissue section is caused to fall off from the glass slide.

To prevent the slice from falling off the glass slide, a bonding agent with higher bonding strength or a mechanical positioning mode is generally adopted to prevent the slice from falling off, however, the chemical bonding agent with higher bonding strength can cause cell degeneration or tissue tearing in pathological tissues; therefore, experimenters limit the slice coverage on the glass slide by adopting a filter screen, prevent the slice from falling off and entering the dye liquor in the dye vat, pollute the dye liquor and influence the reutilization of the dye liquor.

However, the above-mentioned manner of limiting the slice falling off by the filter screen still has some problems, for example, the slice tissue will be swelled by water after being dyed in the dye vat, under the limitation of the filter screen, the slice tissue swelled by water is limited by the mesh edge of the filter screen, the broken tissue is extremely easy to be broken by compression and to be free into the dyeing solution, the pollution solution, for example, the falling off tissue fragments are free in the solution, the falling off tissue of the previous dyeing may be attached to the tissue of the next dyeing, and the slice tissue is polluted, and the slice tissue cannot be used; therefore, except for the experimenter, a layer of filter paper is coated on the outer side surface of the filter screen to prevent broken tissues from entering the dye liquor. However, the speed of dyeing through the filter paper is obviously reduced compared with that of the filter paper due to the arrangement of the filter paper, so that the slice tissues are contacted with the dye liquor, the time required for dyeing is prolonged, and the dyeing efficiency is reduced.

Disclosure of Invention

The invention provides a pathology department specimen slice dyeing device, which aims to solve the problems that: the filter paper is arranged, so that the speed of dyeing penetrating through the filter paper is obviously reduced compared with that of dyeing, further, the slice tissues are contacted with the dye liquor, the time required for dyeing is prolonged, and the dyeing efficiency is reduced.

In order to achieve the above purpose, the invention provides a specimen slice dyeing device of a pathology department, which comprises a machine case and a slide frame, wherein the slide frame is used for installing a plurality of slides with specimen slices, a plurality of dye vats are arranged in the machine case, a mechanical arm is also arranged in the machine case, and the mechanical arm is used for conveying the slide frame into the dye vats to dye the specimen slices on the slides; at least one holding assembly is mounted on the slide mount; the holding component comprises a supporting frame, the supporting frame is used for clamping a glass slide, a fixing frame is arranged below the supporting frame, a filter screen is arranged in the fixing frame and used for pressing a sample slice on the surface of the glass slide, filter paper is arranged on the lower surface of the fixing frame, the glass slide, the fixing frame and the filter paper jointly enclose an inner cavity, the filter paper is used for limiting the sample slice in the inner cavity, an inlet channel is formed in the inner side of the fixing frame, the inlet channel is provided with a section of micro-pore channel, and the micro-pore channel is used for limiting dye liquor in a dye vat to enter the inner cavity in a unidirectional manner; the output end of the mechanical arm is provided with a rotary driving part, the output end of the rotary driving part is provided with a clamping assembly, the clamping assembly is used for clamping a slide frame, and when the dyeing is carried out, the rotary driving part drives the clamping assembly and the slide frame to rotate, and liquid in the dye vat enters the inner cavity from the inlet channel.

In a preferred embodiment, the slide frame includes several montants, mount fixed mounting is on the montant, and the below lid of mount has closed the pressure disk, and filter paper glues the upper surface at the pressure disk, and the one end of pressure disk is the link, and the other end is the free end, and the link rotates to be connected on the mount, and the free end passes through adapting unit and is connected with the mount can dismantle, has seted up vertical groove on the lateral wall of montant, and the free end of pressure disk can slide in the inside of vertical groove, and one side of pressure disk extends there is the extension, is provided with the fixed block that corresponds with the extension on the inside wall of dye vat, and when the fixed block extrudeed the extension downwards, the free end of pressure disk rotates downwards in order to open the inner chamber.

In a preferred embodiment, the connecting end of the pressing plate is hinged with a rotating seat, the rotating seat is rotationally connected with the bottom of the fixing frame, an elastic block is arranged at the bottom of the vertical groove, and when the free end of the pressing plate downwardly extrudes the elastic block to move out of the vertical groove, the pressing plate can rotate by taking the axis of the rotating seat as the outer side of the axial slide frame.

In a preferred embodiment, the inner side wall of the support frame has a plurality of notches, and the upper and lower surfaces of the notches are each provided with elastic rubber, so that the support frame holds the slide by inserting the slide between the two elastic rubbers.

In a preferred embodiment, the support frame is movably sleeved on the vertical rod, and a spring is installed at the upper end of the support frame and used for resetting the support frame downwards.

In a preferred embodiment, the clamping assembly comprises a shell, a driving motor is installed in the shell, clamping blocks are slidably connected to two sides of the lower portion of the shell, a rotary table is installed on an output shaft of the driving motor, connecting rods are arranged on two sides of the rotary table, one ends of the connecting rods are hinged to the edge of the bottom surface of the rotary table, the other ends of the connecting rods are hinged to the upper surface of the clamping blocks, retaining holes are transversely formed in the two clamping blocks, inserting rods I are transversely installed on two sides of the upper end of a vertical rod, and when the clamping assembly clamps a slide frame, the inserting rods I are respectively inserted into the retaining holes.

In a preferred embodiment, the mechanical arm comprises a fixed seat, a big arm and a small arm which are connected in sequence, and the rotary driving part is arranged at the front end of the small arm.

In a preferred embodiment, the device further comprises a YZ-axis driving assembly, wherein the YZ-axis driving assembly comprises a Z-axis moving part for driving the mechanical arm to move along a Z axis and a Y-axis moving part for driving the mechanical arm to move along a Y axis, and the mechanical arm is mounted on the Y-axis moving part.

In a preferred embodiment, a cleaning component is further arranged in the slide frame, the cleaning component comprises a suction pump, a straight pipe is arranged at a water outlet of the suction pump, a lower opening is formed in the bottom end of the straight pipe, a side opening is formed in the side face of the bottom end of the straight pipe, two inserting rods II are fixedly connected to two sides of the suction pump, and when the cleaning component is clamped by the clamping component, the two inserting rods II are respectively inserted into the two holding holes.

In a preferred embodiment, one dye vat is selected as a water washing vat, one dye vat is selected as a waste liquid vat, and the water washing vat and the waste liquid vat are provided with a water inlet pipe and a water outlet pipe, and each water inlet pipe is provided with a water pump.

The invention has the technical effects and advantages that:

the invention can prevent the broken tissue formed by the water swelling and cracking of the sample tissue from entering the dye vat to pollute the dye liquor, can control the dye liquor to enter the inner cavity to dye the sample slice, and can make the sample slice contact with the solution at a higher speed under the combined action of the double dyeing of the external dye liquor and the contact of the sample slice through the filter paper, thereby improving the dyeing and soaking efficiency and shortening the dyeing time.

The invention can prevent broken tissues from entering the dye vat from the position to pollute the solution and avoid the problem of cross contamination among tissues by arranging the micro-pore channels.

According to the invention, the pressure plate is arranged in a mode of being opened downwards, so that flowing water can be directly contacted with the specimen slice during flowing water flushing, and the efficiency of flowing water flushing is improved.

The invention is by the following. The pressure plate is arranged in a mode of being opened outwards, and the upper surface of the pressure plate is exposed after the pressure plate is opened, so that a worker can paste filter paper conveniently.

Drawings

Fig. 1 is a schematic diagram of the overall structure of the present invention.

Fig. 2 is a schematic diagram of the internal structure of the present invention.

Fig. 3 is a schematic diagram of the internal structure of the present invention.

Fig. 4 is a schematic diagram of a partial structure of the present invention.

Fig. 5 is a schematic diagram of a partial structure of the present invention.

Fig. 6 is a schematic structural view of the clamping assembly of the present invention.

Fig. 7 is a schematic view of the mounting of the slide holder and retaining assembly of the present invention.

Fig. 8 is a partial cross-sectional view of the front view of fig. 7 in accordance with the present invention.

Fig. 9 is a partial schematic view of the structure of fig. 8 according to the present invention.

Fig. 10 is an enlarged view of a portion of fig. 9 a in accordance with the present invention.

Fig. 11 is an exploded view of the retention assembly of the present invention.

Fig. 12 is a schematic view of a retention assembly of the present invention.

Fig. 13 is a schematic structural view of the fixing frame of the present invention.

Fig. 14 is a partial enlarged view of the present invention at B in fig. 1.

The reference numerals are: 1. a slide holder; 11. a vertical rod; 111. a vertical groove; 112. an elastic block; 12. the first inserting rod is arranged; 2. a retention assembly; 20. a glass slide; 21. a support frame; 211. a notch; 212. an elastic rubber; 213. a protruding portion; 22. a fixing frame; 221. an inlet passage; 222. a microchannel; 23. a filter screen; 24. a filter paper; 25. an inner cavity; 26. a pressure plate; 261. a rotating seat; 262. an extension; 263. a pin shaft; 27. a spring; 28. a magnet group; 3. a chassis; 4. a dye vat; 41. a fixed block; 5. a mechanical arm; 51. a fixing seat; 52. a large arm; 53. a forearm; 6. a rotation driving part; 7. a clamping assembly; 71. a housing; 72. a drive motor; 73. clamping blocks; 731. a holding hole; 74. a turntable; 75. a connecting rod; 8. a YZ axis drive assembly; 81. a Z-axis moving member; 82. a Y-axis moving member; 9. cleaning the assembly; 91. a suction pump; 92. a straight pipe; 93. a lower opening; 94. a side opening; 95. the second inserting rod is arranged; 100. a water washing tank; 110. a waste liquid cylinder; 120. and (3) a water pump.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

Referring to fig. 1-14 of the specification, a specimen slice dyeing device for a pathology department comprises a machine case 3 and a slide frame 1, wherein the slide frame 1 is used for installing a plurality of slides 20 with specimen slices, a plurality of dye vats 4 are arranged in the machine case 3, a mechanical arm 5 is also arranged in the machine case 3, and the mechanical arm 5 is used for conveying the slide frame 1 into the dye vats 4 and dyeing the specimen slices on the slides 20; at least one holding assembly 2 is mounted on the slide holder 1; the holding component 2 comprises a support frame 21, the support frame 21 is used for clamping a glass slide 20, a fixing frame 22 is arranged below the support frame 21, a filter screen 23 is arranged in the fixing frame 22, the filter screen 23 is used for pressing a sample slice on the surface of the glass slide 20, filter paper 24 is arranged on the lower surface of the fixing frame 22, the glass slide 20, the fixing frame 22 and the filter paper 24 jointly enclose an inner cavity 25, the filter paper 24 is used for limiting the sample slice in the inner cavity 25, an inlet channel 221 is formed in the inner side of the fixing frame 22, the inlet channel 221 is provided with a section of micro-pore channel 222, and the micro-pore channel 222 is used for limiting dye liquor in the dye vat 4 to enter the inner cavity 25 in a unidirectional manner; the output end of the mechanical arm 5 is provided with a rotary driving part 6, the output end of the rotary driving part 6 is provided with a clamping assembly 7, the clamping assembly 7 is used for clamping the slide frame 1, and during dyeing, the rotary driving part 6 drives the clamping assembly 7 and the slide frame 1 to rotate, and liquid in the dye vat 4 enters the inner cavity 25 from the inlet channel 221.

In the above description, the number of the dye vats 4 may be set according to the dyeing requirement, and the HE dyeing basic steps are as follows: dewaxing xylene; sequentially soaking with absolute ethanol, 95% ethanol, 85% ethanol, 75% ethanol, and 65% ethanol; flushing with running water; the sections are stained with hematoxylin dye solution; differentiation of 1% ethanol hydrochloride; returning blue with 1% ammonia water; dyeing in eosin dye solution; the slices are sequentially soaked in 75% ethanol, 85% ethanol, 95% ethanol and absolute ethanol. These solutions are held using a dye vat 4; the mechanical arm 5 is a multi-axis mechanical arm and is used for driving the slide frame 1 to move in multiple degrees of freedom.

It should be further noted that, the inlet channel 221 is in a flared shape, and is used for gathering and pressing the dye liquor into the micro-channel 222 during rotation, and entering the inner cavity 25 through the micro-channel 222, when the slide frame 1 is static in the dye vat 4, the dye liquor cannot enter the inner cavity 25 through the micro-channel 222 under the tension action of the dye liquor, specifically, the micro-channel 222 is a narrow and slender channel, the dye liquor cannot enter under the condition of a certain water pressure, and the inner diameter of the micro-channel 222 can be actually designed based on the depth water pressure of the dye liquor and the capillary blocking degree of the micro-channel 222 in the current dyeing process, so long as the limiting capacity of the micro-channel 222 is designed to the extent that the static dye liquor in the dye vat 4 cannot naturally flow through the micro-channel 222.

It should be further noted that, when the slide 20, the fixing frame 22 and the filter paper 24 together define an inner cavity 25, and the slide frame 1 is statically positioned in the dye vat 4, the dye solution in the dye vat 4 can still enter the inner cavity 25 through the meshes of the filter paper 24 and the filter screen 23 at a certain speed, so as to dye the specimen slice in the inner cavity 25, but the dyeing speed and the dyeing efficiency are low.

Further, the robot arm 5 includes a fixed seat 51, a large arm 52, and a small arm 53 connected in this order, and the rotation driving part 6 is mounted at the front end of the small arm 53, and the large arm 52 and the small arm 53 are respectively equipped with a driving motor.

The tail end of the mechanical arm 5 is the front end of the small arm 53, the rotary driving part 6 can adopt a device for driving parts to rotate, such as a speed reducing motor, an output shaft of the rotary driving part is arranged downwards, and the clamping assembly 7 can adopt a pneumatic clamping jaw structure.

In this embodiment, the implementation scenario specifically includes: when the specimen slice is dyed, the mechanical arm 5 drives the clamping component 7 to move to the position where the slide frame 1 is placed, the clamping component 7 clamps the slide frame 1, the slide frame 1 is clamped into the dye vat 4 filled with the solution for dip dyeing, the liquid passes through the filter paper 24 at a slower speed, so that in order to shorten the dip time, the slide frame 1 is required to be driven to rotate by the rotary driving component 6, the opening of the inlet channel 221 is arranged along the tangential direction of the edge of the fixing frame 22 and is in a flaring shape, during the rotation (clockwise direction in the overlook direction of fig. 7), the solution can enter from the inlet channel 221 and generate larger pressure to overcome the capillary resistance of the micro-pore channel 222, so that the dye liquor is pressed into the micro-pore channel 222, enters the interior of the inner cavity 25 to be fully contacted with the specimen slice, and the dye liquor of the inner cavity 25 is diffused into the dye vat 4 through the filter paper 24. While in the non-rotating process, at the location of the micro-channels 222, the solution cannot pass in and out from there due to the tension of the water, and the dye solution can only pass through the filter paper 24 into the cavity 25.

The invention can prevent the broken tissues formed by the water swelling and cracking of the sample tissues from entering the dye vat 4 to pollute the dye liquor through the filter paper 24, and can control the dye liquor to enter the inner cavity 25 to dye the sample slices by adopting a unique dyeing mode of rotating the holding component 2, and can lead the sample slices to contact with the solution at a higher speed under the combined action of the double dyeing of the external dye liquor and the contact of the sample slices through the filter paper 24, thereby improving the dyeing and soaking efficiency, shortening the dyeing time, and preventing the broken tissues from entering the dye vat 4 from the place to pollute the solution and avoiding the problem of cross contamination among tissues through the arrangement of the micro-pore channels 222.

In the above, as shown in fig. 13, the fixing frame 22 adopts a split structure, that is, an upper part and a lower part, are respectively injection molded, and then are clamped together through the pin posts, so that the processing is convenient.

Further, the inner side wall of the support frame 21 has a plurality of notches 211, and both upper and lower surfaces of the notches 211 are provided with elastic rubbers 212, so that the support frame 21 holds the slide 20 by inserting the slide 20 between the two elastic rubbers 212.

When the slide 20 is mounted, the slide 20 is horizontally inserted from one side of the slide holder 1 to the space between the notches 211, and the slide 20 is held by the elastic rubber 212.

Further, the supporting frame 21 is movably sleeved on the vertical rod 11, and a spring 27 is installed at the upper end of the supporting frame 21, and the spring 27 is used for resetting the supporting frame 21 downwards.

It should be noted that, the protruding portion 213 is provided on one side of the support 21, when the slide 20 is mounted, the protruding portion 213 may be pulled upward, and after the slide 20 is mounted, the protruding portion 213 is released, and when the spring 27 resets the support 21, the filter screen 23 may press the specimen slice. The purpose of this is to prevent the screen 23 from scratching the specimen slice when it is directly inserted into the slide 20.

Referring to fig. 1-14 of the specification, the slide rack 1 includes a plurality of vertical rods 11, the fixing frame 22 is fixedly mounted on the vertical rods 11, the platen 26 is covered under the fixing frame 22, the filter paper 24 is adhered on the upper surface of the platen 26, one end of the platen 26 is a connection end, the other end is a free end, the connection end is rotatably connected to the fixing frame 22, the free end is detachably connected with the fixing frame 22 through a connection part, a vertical groove 111 is formed on a side wall of the vertical rods 11, the free end of the platen 26 can slide in the vertical groove 111, an extension portion 262 extends out of one side of the platen 26, a fixing block 41 corresponding to the extension portion 262 is arranged on an inner side wall of the dye vat 4, and when the fixing block 41 presses the extension portion 262 downwards, the free end of the platen 26 rotates downwards to open the inner cavity 25.

In the above description, the connection member may be in a form of mating with a concave-convex groove, or may be in a form of magnet attraction, and the free end of the platen 26 may be provided with a pin 263, so that the pin 263 slides in the vertical groove 111, as shown in fig. 10, a magnet set 28 is used, that is, a magnet is provided on the upper surface of the platen 26, a magnet opposite to the magnet is provided on the lower surface of the fixing frame 22, and the free end of the platen 26 is mounted on the lower surface of the fixing frame 22 by attraction of the magnet. In the process of flushing by using running water, the flushing water is discharged and cannot be reused, so that the problem of cross contamination of tissues cannot be caused at the position, and therefore, the mechanical arm 5 can drive the slide frame 1 to enable the extension part 262 to be located below the fixed block 41 and then drive the slide frame 1 to move upwards, at the moment, the fixed block 41 can press the extension part 262 downwards, the free end of the pressure plate 26 can rotate downwards to open the inner cavity 25, the running water can be directly contacted with a specimen slice, and the efficiency of flushing by the running water is improved. When the pressure plate 26 is closed, the opposite operation is performed, so that the extension 262 is located above the fixed block 41, and the fixed block 41 pushes the pressure plate 26 to rotate upwards, so that the magnet group 28 is attracted.

Further, one dye vat 4 is selected as a washing vat 100, one dye vat 4 is selected as a waste liquid vat 110, the washing vat 100 and the waste liquid vat 110 are provided with a water inlet pipe and a water outlet pipe, and each water inlet pipe is provided with a water pump 120.

It should be noted that the above-mentioned running water flushing may be performed in the water tub 100, and the water inlet end of the water pump 120 is connected to an external water supply device or a water tub. The purpose of the waste liquid tank 110 is to reduce contamination of the subsequent solution when the solution in the inner chamber 25 needs to be thrown away, such as after hematoxylin staining, by throwing away a part of the hematoxylin, which can be performed in the same manner as the operation of opening and closing the pressure plate 26 in the waste liquid tank 110, but the water pump 120 connected to the waste liquid tank 110 is used for discharging waste liquid or a washing function when not in use.

Further, the connecting end of the pressing plate 26 is hinged with a rotating seat 261, the rotating seat 261 is rotationally connected with the bottom of the fixing frame 22, an elastic block 112 is arranged at the bottom of the vertical groove 111, and when the free end of the pressing plate 26 downwardly presses the elastic block 112 to move out of the vertical groove 111, the pressing plate 26 can rotate by taking the axis of the rotating seat 261 as the outer side of the axial slide frame 1.

It should be noted that, the elastic block 112 may be a rubber block, and the purpose of the elastic block 112 is that when the platen 26 is opened in the washing cylinder 100 and the waste liquid cylinder 110, the pin 263 slides in the vertical groove 111 and cannot move out of the vertical groove 111, and when a worker needs to paste a new filter paper 24 on the platen 26, the space is small, the operation is not easy, the platen 26 can be pulled downward with force, the elastic block 112 is compressed, the pin 263 moves out of the vertical groove 111, then the platen 26 can be rotated out of the inside of the slide frame 1 by rotating the platen 26 toward the outside of the slide frame 1, at this time, the upper surface of the platen 26 is exposed, and the worker is convenient to paste the filter paper 24. The platen 26 is rotated to operate relatively.

With reference to figures 1-8 of the drawings, a new clamping assembly 7 is designed to stabilize the clamping, as opposed to the above. Specifically, the clamping assembly 7 includes a housing 71, a driving motor 72 is installed in the housing 71, two sides below the housing 71 are slidably connected with clamping blocks 73, a turntable 74 is installed on an output shaft of the driving motor 72, two sides of the turntable 74 are respectively provided with a connecting rod 75, one end of the connecting rod 75 is hinged with an edge of the bottom surface of the turntable 74, the other end of the connecting rod is hinged with the upper surface of the clamping blocks 73, two clamping blocks 73 are respectively transversely provided with a retaining hole 731, two sides of the upper end of a vertical rod 11 are respectively transversely provided with a first inserting rod 12, and when the clamping assembly 7 clamps a slide frame 1, the first inserting rods 12 are respectively inserted into the two retaining holes 731.

It should be noted that, the turntable 74 is driven by the driving motor 72 to rotate, so that the turntable 74 can drive the two connecting rods 75 to rotate, and therefore, when the connecting rods 75 pull or push the two clamping blocks 73 to approach or separate from each other, and clamp the vertical rod 11, the mechanical arm 5 moves the clamping assembly 7 above the vertical rod 11, so that the holding hole 731 is aligned with the first inserting rod 12, then the two clamping blocks 73 are close to each other, the first inserting rod 12 is inserted into the holding hole 731, and one end of the first inserting rod 12 is pressed by the side wall of the clamping block 73 to achieve clamping, and the clamping is more stable than direct clamping.

Referring to fig. 1 to 4 of the drawings, a YZ axis driving assembly 8 is provided to drive the robot arm 5 to move along the Z axis and the Y axis to increase a working space of the robot arm 5, and in particular, the YZ axis driving assembly 8 includes a Z axis moving part 81 for driving the robot arm 5 to move along the Z axis, a Y axis moving part 82 for driving the robot arm 5 to move along the Y axis, and the robot arm 5 is mounted on the Y axis moving part 82.

It should be noted that, the Z-axis moving member 81 may be a screw rod sliding table mechanism, and the Y-axis moving member 82 may be a synchronous belt driving manner, that is, a slide block is provided on the synchronous belt, the slide block is fixed with the synchronous belt, and the slide block is slidably mounted on a transverse guide rail to improve stability, so that the fixing seat 51 is mounted on the slide block.

Referring to fig. 1 and 14 of the specification, for cleaning convenience, a cleaning assembly 9 is further disposed in the slide frame 1, the cleaning assembly 9 includes a suction pump 91, a straight pipe 92 is installed at a water outlet of the suction pump 91, a lower opening 93 is formed at a bottom end of the straight pipe 92, a side opening 94 is formed at a side surface of the bottom end, two inserting rods 95 are fixedly connected to two sides of the suction pump 91, and when the cleaning assembly 9 is clamped by the clamping assembly 7, the two inserting rods 95 are respectively inserted into the two holding holes 731.

It should be noted that, the two sides of the suction pump 91 are provided with the two inserting rods 95, which are consistent with the first inserting rod 12 on the slide frame 1 in function, so as to facilitate the clamping of the clamping assembly 7, the suction of the suction pump 91 is controlled by controlling the forward and reverse rotation of the suction pump 91, the mechanical arm 5 sends the cleaning assembly 9 to the inside of the dye vat 4, the suction pump 91 sprays water to the dye vat 4, the water flows out from the lower opening 93 and the side opening 94, thereby the dye vat 4 is cleaned, the rotary driving part 6 can drive the clamping assembly 7 to swing at a small reciprocating angle, so that the cleaning can be fully performed, and after the water spraying is completed, the water is absorbed outwards through the suction pump 91. When spraying water, the water inlet of the suction pump 91 is connected to the water supply device or the water tank, and when sucking water, the suction pump needs to be connected to the waste water tank, and a hose connected with the suction pump can be manually operated, or an electric reversing valve can be used.

Finally: the foregoing description of the preferred embodiments of the invention is not intended to limit the invention to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and principles of the invention are intended to be included within the scope of the invention.

Claims (8)

1. The utility model provides a pathology department's sample section dyeing equipment which characterized in that: comprises a slide frame (1), wherein the slide frame (1) is provided with a plurality of vertical rods (11), and at least one retaining component (2) is arranged on the slide frame (1);

the holding assembly (2) comprises a supporting frame (21) arranged on the vertical rod (11), the supporting frame (21) is used for clamping the glass slide (20), a fixing frame (22) fixedly arranged on the vertical rod (11) is arranged below the supporting frame (21), a filter screen (23) is arranged in the fixing frame (22), the filter screen (23) is used for pressing slices on the surface of the glass slide (20), filter paper (24) is arranged on the lower surface of the fixing frame (22), the glass slide (20), the fixing frame (22) and the filter paper (24) jointly enclose an inner cavity (25), an inlet channel (221) is formed in the inner side of the fixing frame (22), and the inlet channel (221) is provided with a section of micro-channel (222);

the automatic dyeing machine is characterized by further comprising a machine case (3), wherein a plurality of dye vats (4) are arranged in the machine case (3), a mechanical arm (5) is further arranged in the machine case (3), a rotary driving part (6) is arranged at the tail end of the mechanical arm (5), a clamping assembly (7) is arranged at the output end of the rotary driving part (6), after the clamping assembly (7) clamps the slide frame (1), the mechanical arm (5) conveys the slide frame (1) into the corresponding dye vats (4), when the rotary driving part (6) drives the clamping assembly (7) and the slide frame (1) to rotate, liquid in the dye vats (4) enters an inner cavity (25) from an inlet channel (221), and when the mechanical arm does not rotate, the liquid cannot pass through a micro-pore channel (222) due to the tension of the liquid;

the utility model discloses a dyeing machine, including fixed frame (22), filter paper, fixed frame (11), fixed frame (22), filter paper (24), fixed frame (22) below is covered and is closed pressure disk (26), filter paper (24) glues the upper surface at pressure disk (26), the one end of pressure disk (26) is the link, and the other end is the free end, and the link rotates to be connected on fixed frame (22), and the free end passes through adapting unit and is connected with fixed frame (22) can dismantle, set up on the lateral wall of montant (11) perpendicular groove (111), the free end of pressure disk (26) can slide in the inside of perpendicular groove (111), one side of pressure disk (26) extends there is extension (262), be provided with fixed block (41) that corresponds with extension (262) on the inside wall of dye vat (4), when fixed block (41) extrudeed extension (262) downwards, the free end of pressure disk (26) rotates downwards in order to open inner chamber (25);

the connecting end of the pressure plate (26) is hinged with a rotating seat (261), the rotating seat (261) is rotationally connected with the bottom of the fixing frame (22), an elastic block (112) is arranged at the bottom of the vertical groove (111), and when the free end of the pressure plate (26) downwards extrudes the elastic block (112) to move out of the vertical groove (111), the pressure plate (26) can rotate by taking the axis of the rotating seat (261) as the outer side of the axial slide frame (1).

2. The pathology department specimen slice staining apparatus according to claim 1, wherein: the inner side wall of the support frame (21) is provided with a plurality of notches (211), elastic rubber (212) are arranged on the upper surface and the lower surface of each notch (211), and the slide glass (20) is clamped by the support frame (21) by inserting the slide glass (20) between the two elastic rubbers (212).

3. A pathology department specimen slice staining apparatus according to claim 1 or 2, wherein: the support frame (21) is movably sleeved on the vertical rod (11), a spring (27) is arranged at the upper end of the support frame (21), and the spring (27) is used for resetting the support frame (21) downwards.

4. The pathology department specimen slice staining apparatus according to claim 1, wherein: the clamping assembly (7) comprises a shell (71), a driving motor (72) is installed in the shell (71), clamping blocks (73) are connected to two sides of the lower portion of the shell (71) in a sliding mode, a rotary table (74) is installed on an output shaft of the driving motor (72), connecting rods (75) are arranged on two sides of the rotary table (74), one end of each connecting rod (75) is hinged to the edge of the bottom surface of the rotary table (74), the other end of each connecting rod is hinged to the upper surface of the corresponding clamping block (73), two retaining holes (731) are formed in the clamping blocks (73) in a transverse mode, inserting rods (12) are arranged on two sides of the upper end of each vertical rod (11) in a transverse mode, and when the clamping assembly (7) clamps a slide frame (1), the inserting rods (12) are inserted into the retaining holes (731) respectively.

5. The pathology department specimen slice staining apparatus according to claim 1, wherein: the mechanical arm (5) comprises a fixed seat (51), a large arm (52) and a small arm (53) which are sequentially connected, and the rotary driving part (6) is arranged at the front end of the small arm (53).

6. The pathology department specimen slice staining apparatus according to claim 5, wherein: the device further comprises a YZ-axis driving assembly (8), wherein the YZ-axis driving assembly (8) comprises a Z-axis moving component (81) for driving the mechanical arm (5) to move along a Z axis and a Y-axis moving component (82) for driving the mechanical arm (5) to move along a Y axis, and the mechanical arm (5) is installed on the Y-axis moving component (82).

7. The pathology department specimen slice staining apparatus according to claim 4, wherein: still be provided with in slide frame (1) and wash subassembly (9), wash subassembly (9) including suction pump (91), straight tube (92) are installed to the delivery port of suction pump (91), side opening (94) have been seted up to the side of straight tube (92) bottom under shed (93) and bottom, the equal fixedly connected with inserted bar two (95) in both sides of suction pump (91), when clamping assembly (7) centre gripping washs subassembly (9), two inserted bars two (95) are inserted respectively in two holding holes (731).

8. The pathology department specimen slice staining apparatus according to claim 1, wherein: one dye vat (4) is selected as a water washing vat (100), one dye vat (4) is selected as a waste liquid vat (110), the water washing vat (100) and the waste liquid vat (110) are provided with a water inlet pipe and a water outlet pipe, and a water pump (120) is arranged on each water inlet pipe.