CN117462427A - A nutritional composition for improving periocular skin fine wrinkles by ultrasound or radio frequency - Google Patents
A nutritional composition for improving periocular skin fine wrinkles by ultrasound or radio frequency Download PDFInfo
- Publication number
- CN117462427A CN117462427A CN202311539127.6A CN202311539127A CN117462427A CN 117462427 A CN117462427 A CN 117462427A CN 202311539127 A CN202311539127 A CN 202311539127A CN 117462427 A CN117462427 A CN 117462427A
- Authority
- CN
- China
- Prior art keywords
- nutritional composition
- lecithin
- extract
- improving
- radio frequency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 65
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 62
- 230000037303 wrinkles Effects 0.000 title claims abstract description 17
- 238000002604 ultrasonography Methods 0.000 title claims description 9
- 235000010445 lecithin Nutrition 0.000 claims abstract description 52
- 239000000787 lecithin Substances 0.000 claims abstract description 52
- 229940067606 lecithin Drugs 0.000 claims abstract description 52
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 29
- 240000008397 Ganoderma lucidum Species 0.000 claims abstract description 25
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims abstract description 25
- 235000014104 aloe vera supplement Nutrition 0.000 claims abstract description 24
- 241000226555 Leontopodium Species 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 21
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims abstract description 20
- 229940083466 soybean lecithin Drugs 0.000 claims abstract description 20
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 19
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 19
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 19
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract description 18
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 17
- 229940101267 panthenol Drugs 0.000 claims abstract description 17
- 235000020957 pantothenol Nutrition 0.000 claims abstract description 17
- 239000011619 pantothenol Substances 0.000 claims abstract description 17
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 17
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 17
- 235000019198 oils Nutrition 0.000 claims abstract description 14
- 235000020238 sunflower seed Nutrition 0.000 claims abstract description 14
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 9
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 229920002125 Sokalan® Polymers 0.000 claims description 9
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 9
- 229960001631 carbomer Drugs 0.000 claims description 9
- 229920005862 polyol Polymers 0.000 claims description 9
- 150000003077 polyols Chemical class 0.000 claims description 9
- 239000000230 xanthan gum Substances 0.000 claims description 9
- 235000010493 xanthan gum Nutrition 0.000 claims description 9
- 229920001285 xanthan gum Polymers 0.000 claims description 9
- 229940082509 xanthan gum Drugs 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 206010040925 Skin striae Diseases 0.000 claims description 8
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 6
- 239000003349 gelling agent Substances 0.000 claims description 6
- 239000003002 pH adjusting agent Substances 0.000 claims description 5
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 3
- 239000004475 Arginine Substances 0.000 claims description 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 3
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 3
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 3
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 3
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 3
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims description 3
- 235000019799 monosodium phosphate Nutrition 0.000 claims description 3
- OEIJHBUUFURJLI-UHFFFAOYSA-N octane-1,8-diol Chemical compound OCCCCCCCCO OEIJHBUUFURJLI-UHFFFAOYSA-N 0.000 claims description 3
- 239000000661 sodium alginate Substances 0.000 claims description 3
- 235000010413 sodium alginate Nutrition 0.000 claims description 3
- 229940005550 sodium alginate Drugs 0.000 claims description 3
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims description 3
- 230000006698 induction Effects 0.000 claims 3
- XPFCZYUVICHKDS-UHFFFAOYSA-N 3-methylbutane-1,3-diol Chemical compound CC(C)(O)CCO XPFCZYUVICHKDS-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 35
- 230000032683 aging Effects 0.000 abstract description 13
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 60
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 24
- 238000011156 evaluation Methods 0.000 description 10
- 108090000790 Enzymes Proteins 0.000 description 8
- 102000004190 Enzymes Human genes 0.000 description 8
- 230000003020 moisturizing effect Effects 0.000 description 8
- 230000008439 repair process Effects 0.000 description 8
- 210000000434 stratum corneum Anatomy 0.000 description 8
- 102000008186 Collagen Human genes 0.000 description 7
- 108010035532 Collagen Proteins 0.000 description 7
- 229920001436 collagen Polymers 0.000 description 7
- 230000008929 regeneration Effects 0.000 description 7
- 238000011069 regeneration method Methods 0.000 description 7
- 150000001413 amino acids Chemical class 0.000 description 6
- 230000003078 antioxidant effect Effects 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 150000004676 glycans Chemical class 0.000 description 6
- 229920001282 polysaccharide Polymers 0.000 description 6
- 239000005017 polysaccharide Substances 0.000 description 6
- 210000004927 skin cell Anatomy 0.000 description 6
- VBOZFTYRQDFTKX-UHFFFAOYSA-N 3-methylbutane-1,1-diol Chemical compound CC(C)CC(O)O VBOZFTYRQDFTKX-UHFFFAOYSA-N 0.000 description 5
- 239000003963 antioxidant agent Substances 0.000 description 5
- 230000003796 beauty Effects 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 5
- 230000003647 oxidation Effects 0.000 description 5
- 238000007254 oxidation reaction Methods 0.000 description 5
- 239000012466 permeate Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 238000000354 decomposition reaction Methods 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 150000003254 radicals Chemical class 0.000 description 4
- 230000004936 stimulating effect Effects 0.000 description 4
- 238000003786 synthesis reaction Methods 0.000 description 4
- 235000013343 vitamin Nutrition 0.000 description 4
- 239000011782 vitamin Substances 0.000 description 4
- 229940088594 vitamin Drugs 0.000 description 4
- 229930003231 vitamin Natural products 0.000 description 4
- PZNPLUBHRSSFHT-RRHRGVEJSA-N 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCCCCCCCCCC PZNPLUBHRSSFHT-RRHRGVEJSA-N 0.000 description 3
- 241000226556 Leontopodium alpinum Species 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 3
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
- 238000005562 fading Methods 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 229920005610 lignin Polymers 0.000 description 3
- 239000011707 mineral Substances 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 239000008347 soybean phospholipid Substances 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 229940083957 1,2-butanediol Drugs 0.000 description 2
- 241001249542 Leonia <angiosperm> Species 0.000 description 2
- 102000019197 Superoxide Dismutase Human genes 0.000 description 2
- 108010012715 Superoxide dismutase Proteins 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 230000003064 anti-oxidating effect Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000032677 cell aging Effects 0.000 description 2
- 201000010251 cutis laxa Diseases 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000002000 scavenging effect Effects 0.000 description 2
- 230000008591 skin barrier function Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 230000002087 whitening effect Effects 0.000 description 2
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 1
- 241001116389 Aloe Species 0.000 description 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 1
- 241000219312 Chenopodium Species 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 235000004866 D-panthenol Nutrition 0.000 description 1
- 239000011703 D-panthenol Substances 0.000 description 1
- 108700041153 Filaggrin Proteins Proteins 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000207925 Leonurus Species 0.000 description 1
- 235000019738 Limestone Nutrition 0.000 description 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 1
- 241000519406 Paphiopedilum Species 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 208000010340 Sleep Deprivation Diseases 0.000 description 1
- 229930003571 Vitamin B5 Natural products 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 description 1
- 229960002079 calcium pantothenate Drugs 0.000 description 1
- 230000020411 cell activation Effects 0.000 description 1
- 230000005779 cell damage Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 208000037887 cell injury Diseases 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- 229940074393 chlorogenic acid Drugs 0.000 description 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 1
- 235000001368 chlorogenic acid Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 108010010779 glutamine-pyruvate aminotransferase Proteins 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000006028 limestone Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000003961 penetration enhancing agent Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 235000009492 vitamin B5 Nutrition 0.000 description 1
- 239000011675 vitamin B5 Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Biomedical Technology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to a nutritional composition for improving periocular skin fine wrinkles by ultrasonic or radio frequency introduction, which comprises panthenol, hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, lecithin/soybean lecithin/hydrogenated lecithin, ganoderma lucidum extract, alpine leontopodium herb extract, sunflower seed oil, aloe vera extract, polyalcohol, gel, pH regulator and water. The invention has mild components, is suitable for being guided into the skin around eyes by utilizing ultrasonic waves or radio frequency, has the effects of repairing the skin, improving the fine wrinkles of the skin around eyes, reducing dark circles, tightening the skin and resisting aging, and is a nutritional composition with excellent effect and high safety.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a nutritional composition for improving skin fine lines around eyes by utilizing ultrasonic or radio frequency introduction.
Background
The eye is the window of the person's mind. However, under fast-paced life, learning and working pressures, stay up is normal for many people. Blood flow velocity of blood vessels of the skin of eyes is too slow to form blood stasis due to the aging, irregular work and rest, insufficient sleep and the like; insufficient oxygen supply to tissues and accumulation of metabolites in blood vessels cause ocular pigmentation to form dark circles; meanwhile, the problems of loose skin around eyes, fine lines, eye bags and the like can be caused. Aging such as wrinkles around eyes and loose skin is likely to cause aging of the whole face, and these problems have been plagued by various beauty-seeking persons.
The radio frequency beauty instrument utilizes the energy of radio frequency wavelength to massage eyes and promote nutrition introduction, and can effectively realize eye care and beauty effect under the use of matching with proper nutrient solution. The ultrasonic wave introduction instrument utilizes ultrasonic waves to bring heat energy through high-frequency vibration, opens pores, promotes nutrition introduction, and can effectively realize eye care and beauty effect under the use of matching with proper nutrient solution.
At present, the nutrition mainly introduced by the radio frequency beauty instrument or the ultrasonic wave introduction instrument is water replenishing essence and the like, and no nutritional composition suitable for the radio frequency beauty instrument or the ultrasonic wave introduction instrument for improving the skin fine lines around eyes exists.
Disclosure of Invention
The present invention has been made in view of the above problems, and has as its object to provide a nutritional composition for improving periocular skin fine lines by ultrasound or radio frequency introduction which overcomes or at least partially solves the above problems.
The embodiment of the invention provides a nutritional composition for improving skin wrinkles around eyes by utilizing ultrasonic or radio frequency introduction, which comprises panthenol, hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, lecithin/soybean lecithin/hydrogenated lecithin, ganoderma lucidum extract, alpine leonia extract, sunflower seed oil and aloe vera extract.
Preferably, the nutritional composition further comprises a polyol, a gelling agent, a pH adjuster and water.
Preferably, the polyol is one or two of glycerol, propylene glycol, octanediol, 1, 2-hexanediol and butanediol.
Preferably, the gel is one or two of carbomer, hydroxyethyl cellulose, sodium alginate and xanthan gum.
Preferably, the pH adjuster is one of potassium hydroxide, sodium hydroxide, disodium hydrogen phosphate, sodium dihydrogen phosphate, triethanolamine, and arginine.
Preferably, the nutritional composition comprises, in weight percent, 0.5% -3% panthenol, 0.1% -0.5% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 1% -5% lecithin/soybean lecithin/hydrogenated lecithin, 5% -12% ganoderma lucidum extract, 5% -10% alpine leontopodium herb extract, 0.1% -1.5% sunflower seed oil, 2% -5% aloe vera extract.
Preferably, the nutritional composition further comprises 0.5-3% of polyol, 0.01-0.5% of gel, 0-0.2% of pH regulator and the balance of water in weight percent.
Preferably, the nutritional composition comprises 2% panthenol, 0.25% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 2% lecithin/soy lecithin/hydrogenated lecithin, 12% red sesame extract, 8% alpine leontopodium extract, 1% sunflower seed oil, 3% aloe vera extract, 0.5% butylene glycol, 0.5% isopentane diol, 0.01% carbomer, 0.01% xanthan gum, 0.01% triethanolamine, balance water, in weight percent.
The nutritional composition for improving skin fine lines around eyes by utilizing ultrasonic or radio frequency introduction disclosed by the embodiment of the invention is prepared by compounding ganoderma lucidum extract, alpine leontopodium herb extract, lecithin/soybean lecithin/hydrogenated lecithin and aloe vera extract. The ganoderma lucidum extract, the alpine leontopodium herb extract and the lecithin/soybean lecithin/hydrogenated lecithin have the oxidation resistance, the lecithin has a structure similar to a biological membrane, the ganoderma lucidum extract has the effect of promoting the regeneration and repair of skin cells, and the alpine leontopodium herb extract can promote the synthesis of collagen and promote the self repair of skin; the three antioxidant components are compounded for use, and the lecithin has a structure similar to a biological film, is easy to permeate the active components into the stratum corneum of the skin, and can play a synergistic role in inhibiting aging and stimulating collagen regeneration in the skin around eyes. The aloe vera extract is rich in mineral substances, lignin, polysaccharide and other components, can supplement water and preserve moisture, and improve the rough skin around eyes, and contains amino acids and vitamins which cannot be synthesized by a human body, so that melanin active enzymes can be effectively stabilized, the activities of the enzymes are inhibited by decomposition, the formed melanin is promoted to be rapidly decomposed and metabolized, the melanin is prevented from being formed again, and the effect of fading black eyes can be achieved. The functions and actions of the various components of the nutritional composition disclosed by the embodiment of the invention can complement and cooperate, and the use effect of the nutritional composition is better than that of the components when the components are used singly or in a mixture. The composition is mild in components, is suitable for being guided into the skin around eyes by utilizing ultrasonic waves or radio frequency, has the effects of repairing the skin, improving the fine wrinkles of the skin around eyes, reducing dark circles, tightening the skin and resisting aging, and is a nutritional composition with excellent effect and high safety.
Detailed Description
The present invention will be further described with reference to examples for the convenience of those skilled in the art.
The embodiment of the invention provides a nutritional composition for improving skin wrinkles around eyes by utilizing ultrasonic or radio frequency introduction, which comprises panthenol, hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, lecithin/soybean lecithin/hydrogenated lecithin, ganoderma lucidum extract, alpine leonia extract, sunflower seed oil and aloe vera extract.
In one embodiment, the nutritional composition further comprises a polyol, a gelling agent, a pH adjuster, and water.
In one embodiment, the polyol is one or two of glycerol, propylene glycol, octanediol, 1, 2-hexanediol, and butanediol.
In one embodiment, the gel is one or two of carbomer, hydroxyethyl cellulose, sodium alginate and xanthan gum.
In one embodiment, the pH adjuster is one of potassium hydroxide, sodium hydroxide, disodium hydrogen phosphate, sodium dihydrogen phosphate, triethanolamine, and arginine.
In one embodiment, the nutritional composition comprises, in weight percent, 0.5% to 3% panthenol, 0.1% to 0.5% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 1% to 5% lecithin/soybean lecithin/hydrogenated lecithin, 5% to 12% ganoderma lucidum extract, 5% to 10% alpine leontopodium herb extract, 0.1% to 1.5% sunflower seed oil, 2% to 5% aloe vera extract.
In one embodiment, the nutritional composition further comprises, in weight percent, 0.5% to 3% polyol, 0.01% to 0.5% gelling agent, 0 to 0.2% ph adjuster, balance water.
In one embodiment, the nutritional composition comprises 2% panthenol, 0.25% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 2% lecithin/soy lecithin/hydrogenated lecithin, 12% ganoderma lucidum extract, 8% alpine leontopodium extract, 1% sunflower seed oil, 3% aloe vera extract, 0.5% butylene glycol, 0.5% isopentane diol, 0.01% carbomer, 0.01% xanthan gum, 0.01% triethanolamine, balance water, by weight.
The nutritional composition for improving the skin striae around eyes by utilizing ultrasonic or radio frequency introduction comprises panthenol, hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, lecithin/soybean lecithin/hydrogenated lecithin, ganoderma lucidum extract, alpine leonurus extract, sunflower seed oil and aloe vera extract. Panthenol, hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, has the functions of preserving water, moisturizing and locking water, has the effects of activating cells and protecting skin, reduces the generation of scars, and improves the elasticity of the skin, thereby achieving the effect of repairing damaged skin. Panthenol, also known as vitamin B5, provitamin B5, has a smaller molecular weight. It can quickly and effectively penetrate into the stratum corneum, moisten the stratum corneum on the skin surface, and plays a role in strong moisturizing. Panthenol can also effectively improve rough skin and soften skin; has effects in repairing skin barrier, stimulating epithelial cell growth, promoting wound healing, and relieving inflammation. The hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, also called low molecular weight hyaluronic acid/sodium hyaluronate or small molecular weight hyaluronic acid/sodium hyaluronate, has the functions of deep moisturizing, antioxidation, aging resistance, cell proliferation promotion and damaged cell repair due to small molecular weight and easy transdermal absorption.
The cosmetic containing lecithin/soybean lecithin/hydrogenated lecithin has continuous softening effect on skin, and can effectively increase water content of horny layer, so that the cosmetic has good moisturizing effect, and has effects of retaining skin moisture and activating skin cells; and the lecithin/soybean lecithin/hydrogenated lecithin is a natural antioxidant, and plays roles in scavenging free radicals and resisting aging; the lecithin/soybean lecithin/hydrogenated lecithin has a structure similar to a biological membrane, and can be used as a penetration enhancer in a cosmetic formula, so that an active substance in the carrying formula permeates into the stratum corneum of skin, and the effect of the active substance is effectively exerted.
The alpine leontopodium is also called as the edelweiss, is native in alpine region, grows on gravel grassland or limestone land with the altitude of 2000-2900 meters, and has the characteristics of large temperature difference, low air pressure, strong ultraviolet radiation, ultralow temperature, strong wind intensity and the like due to the growth environment, and the body surface tissue of the edelweiss evolves into white floss to resist the severe environment. Meanwhile, the novel high-efficiency oxidation-resistant system also forms a set of high-efficiency oxidation-resistant system, and can remove excessive free radicals and harmful substances in a body. The herba Centipedae extract contains various active ingredients beneficial to skin, including edelweiss acid, chlorogenic acid, phytosterol, amino acid, polysaccharide, etc. Among them, chenopodium acid is the most important antioxidant component, and can promote collagen synthesis, activate mitochondrial network, and promote skin self-repair. The alpine leontopodium herb extract not only has high-efficiency antioxidation, protects DNA and protein, but also can up-regulate the expression of glutamine transaminase TG1, crust protein, paphiopedilum protein, filaggrin and the like in epidermal cells so as to strengthen skin barrier.
The Ganoderma lucidum extract has antioxidant effect, and can help neutralize harmful free radicals, thereby reducing risk of cell damage, and further slowing down aging process. Secondly, the ganoderma lucidum extract can also promote regeneration and repair of skin cells, improve skin quality, enable skin to be smoother and finer, and delay appearance of wrinkles and slackens of skin.
The aloe vera extract has the functions of moisturizing, moisturizing and forming a layer of very thin breathable film on the surface layer of the skin while penetrating into the skin deeply, so that the evaporation of skin moisture is blocked, the polysaccharide component and amino acid substances after penetrating into the skin have very obvious moisturizing, moisturizing and softening effects, the adsorptivity and water binding property of the stratum corneum are enhanced, the effects of activating and moisture filling the skin and the dry stratum corneum which lose elasticity are quickly achieved, and the original smoothness, softness and good elasticity of the skin are recovered. The aloe vera extract also has the effects of whitening and lightening spots, contains amino acids and vitamins which cannot be synthesized by a human body, and can effectively stabilize melanin active enzymes. Can decompose and inhibit enzyme activity, promote rapid decomposition and metabolism of melanin, prevent melanin from forming again, and achieve effects of whitening skin and removing speckle. The aloe vera extract also has anti-aging effect, and has the important effects of scavenging free radicals, preventing cell aging and treating chronic allergy by using superoxide dismutase (SOD) with aloe polysaccharides as core. The cells are accelerated to divide and activate, so that the cells can quickly permeate into basal layers of human skin; meanwhile, the skin cell activation is promoted, the cell aging is delayed, and the skin elasticity and compactness are recovered.
The nutritional composition for improving skin fine lines around eyes by utilizing ultrasonic or radio frequency introduction disclosed by the embodiment of the invention is prepared by compounding ganoderma lucidum extract, alpine leontopodium herb extract, lecithin/soybean lecithin/hydrogenated lecithin and aloe vera extract. The ganoderma lucidum extract, the alpine leontopodium herb extract and the lecithin/soybean lecithin/hydrogenated lecithin have the oxidation resistance, the lecithin has a structure similar to a biological membrane, the ganoderma lucidum extract has the effect of promoting the regeneration and repair of skin cells, and the alpine leontopodium herb extract can promote the synthesis of collagen and promote the self repair of skin; the three antioxidant components are compounded for use, and the lecithin has a structure similar to a biological film, is easy to permeate the active components into the stratum corneum of the skin, and can play a synergistic role in inhibiting aging and stimulating collagen regeneration in the skin around eyes. The aloe vera extract is rich in mineral substances, lignin, polysaccharide and other components, can supplement water and preserve moisture, and improve the rough skin around eyes, and contains amino acids and vitamins which cannot be synthesized by a human body, so that melanin active enzymes can be effectively stabilized, the activities of the enzymes are inhibited by decomposition, the formed melanin is promoted to be rapidly decomposed and metabolized, the melanin is prevented from being formed again, and the effect of fading black eyes can be achieved. The functions and actions of the various components of the nutritional composition disclosed by the embodiment of the invention can complement and cooperate, and the use effect of the nutritional composition is better than that of the components when the components are used singly or in a mixture. The composition is mild in components, is suitable for being guided into the skin around eyes by utilizing ultrasonic waves or radio frequency, has the effects of repairing the skin, improving the fine wrinkles of the skin around eyes, reducing dark circles, tightening the skin and resisting aging, and is a nutritional composition with excellent effect and high safety.
The above-described nutritional composition for improving periocular skin fine wrinkles using ultrasonic or radio frequency introduction is described in further detail below in connection with specific examples and comparative examples.
Example 1
A nutritional composition for improving periocular skin striae by ultrasonic or radio frequency introduction comprises, by weight, 2% panthenol, 0.25% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 2% lecithin/soybean lecithin/hydrogenated lecithin, 12% Ganoderma lucidum extract, 8% alpine leontopodium herb extract, 1% sunflower seed oil, 3% aloe vera extract, 0.5% butylene glycol, 0.5% isopentane diol, 0.01% carbomer, 0.01% xanthan gum, 0.01% triethanolamine, and the balance water. The nutritional composition is gel-like.
Example 2
A nutritional composition for improving periocular skin striae by ultrasonic or radio frequency introduction comprises, by weight, 2% panthenol, 0.25% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 2% lecithin/soybean lecithin/hydrogenated lecithin, 10% Ganoderma lucidum extract, 6% alpine leontopodium herb extract, 1% sunflower seed oil, 2% aloe vera extract, 0.5% butanediol, 0.5% isopentane diol, 0.01% carbomer, 0.01% xanthan gum, 0.01% triethanolamine, and the balance water. The nutritional composition is gel-like.
Comparative example
A nutritional composition comprising, in parts by weight, 2% panthenol, 0.25% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 2% lecithin/soy lecithin/hydrogenated lecithin, 1% sunflower seed oil, 0.5% butylene glycol, 0.5% isopentane diol, 0.01% carbomer, 0.01% xanthan gum, 0.01% triethanolamine, balance water. The nutritional composition is gel-like.
The nutritional compositions of example 1, example 2, and comparative example were introduced into the periocular skin by ultrasound, and evaluated by subjects and dermatologists after 4 weeks, respectively, with 36 female subjects aged within the 30-40 years. In the test process, the test subjects normally work and feel, smoking and drinking are forbidden, and other skin care products and cosmetics are not smeared around eyes. In each test, the ultrasonic wave introduction instrument adopts instruments of the same model, and the setting parameters are the same. The evaluation results were expressed as 0 to 9 points, and the larger the number, the higher the evaluation of the effect of improving the fine wrinkles of the skin around the eyes. The specific evaluation results are shown in tables 1,2 and 3.
Table 1: example 1 nutritional composition test evaluation
Table 2: example 2 nutritional composition test evaluation
Table 3: comparative example nutritional composition test evaluation
The average value of the nutritional composition test evaluation of example 1 was 8.2, the average value of the nutritional composition test evaluation of example 2 was 7.95, and the average value of the comparative nutritional composition test evaluation was 5.9, except for the highest and lowest average values of the respective evaluations in tables 1,2 and 3. From the test results, it was found that the nutritional composition of example 1, which contained higher amounts of ganoderma lucidum extract, alpine leonardite extract, aloe vera extract, had slightly better effect on improving periocular skin fine wrinkles than the nutritional composition of example 2, which contained lower amounts of ganoderma lucidum extract, alpine leonardite extract, aloe vera extract. The nutritional compositions of example 1 and the nutritional composition of example 2 are all significantly better than the comparative nutritional composition in improving the skin striae around the eyes.
The nutritional composition for improving skin fine lines around eyes by utilizing ultrasonic or radio frequency introduction disclosed by the embodiment of the invention is prepared by compounding ganoderma lucidum extract, alpine leontopodium herb extract, lecithin/soybean lecithin/hydrogenated lecithin and aloe vera extract. The ganoderma lucidum extract, the alpine leontopodium herb extract and the lecithin/soybean lecithin/hydrogenated lecithin have the oxidation resistance, the lecithin has a structure similar to a biological membrane, the ganoderma lucidum extract has the effect of promoting the regeneration and repair of skin cells, and the alpine leontopodium herb extract can promote the synthesis of collagen and promote the self repair of skin; the three antioxidant components are compounded for use, and the lecithin has a structure similar to a biological film, is easy to permeate the active components into the stratum corneum of the skin, and can play a synergistic role in inhibiting aging and stimulating collagen regeneration in the skin around eyes. The aloe vera extract is rich in mineral substances, lignin, polysaccharide and other components, can supplement water and preserve moisture, and improve the rough skin around eyes, and contains amino acids and vitamins which cannot be synthesized by a human body, so that melanin active enzymes can be effectively stabilized, the activities of the enzymes are inhibited by decomposition, the formed melanin is promoted to be rapidly decomposed and metabolized, the melanin is prevented from being formed again, and the effect of fading black eyes can be achieved. The functions and actions of the various components of the nutritional composition disclosed by the embodiment of the invention can complement and cooperate, and the use effect of the nutritional composition is better than that of the components when the components are used singly or in a mixture. The composition is mild in components, is suitable for being guided into the skin around eyes by utilizing ultrasonic waves or radio frequency, has the effects of repairing the skin, improving the fine wrinkles of the skin around eyes, reducing dark circles, tightening the skin and resisting aging, and is a nutritional composition with excellent effect and high safety.
The foregoing examples illustrate only a few embodiments of the invention and are described in detail herein without thereby limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.
Claims (8)
1. A nutritional composition for improving periocular skin striae by ultrasound or radio frequency introduction, characterized in that the nutritional composition comprises panthenol, hydrolyzed hyaluronic acid/sodium hydrolyzed hyaluronic acid, lecithin/soybean lecithin/hydrogenated lecithin, ganoderma lucidum extract, alpine leontopodium herb extract, sunflower seed oil, aloe vera extract.
2. The nutritional composition for improving periocular skin fine lines using ultrasound or radio frequency induction according to claim 1, characterized in that it further comprises a polyol, a gelling agent, a pH regulator and water.
3. The nutritional composition for improving periocular skin fine wrinkles using ultrasonic or radio frequency introduction of claim 2 wherein the polyol is one or two of glycerin, propylene glycol, octanediol, 1, 2-hexanediol, butylene glycol.
4. The nutritional composition for improving periocular skin fine wrinkles using ultrasonic or radio frequency introduction of claim 2 wherein the gelling agent is one or two of carbomer, hydroxyethyl cellulose, sodium alginate, xanthan gum.
5. The nutritional composition for improving periocular skin striae using ultrasound or radio frequency induction of claim 2, wherein the pH adjuster is one of potassium hydroxide, sodium hydroxide, disodium hydrogen phosphate, sodium dihydrogen phosphate, triethanolamine, and arginine.
6. The nutritional composition for improving periocular skin striae using ultrasound or radio frequency introduction according to claim 1, characterized in that it comprises, in weight percent, 0.5% to 3% panthenol, 0.1% to 0.5% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 1% to 5% lecithin/soybean lecithin/hydrogenated lecithin, 5% to 12% ganoderma lucidum extract, 5% to 10% alpine leontopodium extract, 0.1% to 1.5% sunflower seed oil, 2% to 5% aloe vera extract.
7. The nutritional composition for improving periocular skin fine wrinkles using ultrasonic or radio frequency introduction according to any of claims 2 to 5, characterized in that it further comprises, in weight percent, 0.5% to 3% of a polyol, 0.01% to 0.5% of a gelling agent, 0 to 0.2% of a ph regulator, the balance being water.
8. The nutritional composition for improving periocular skin striae using ultrasound or radio frequency induction of claim 7, wherein the nutritional composition comprises 2% panthenol, 0.25% hydrolyzed hyaluronic acid/hydrolyzed sodium hyaluronate, 2% lecithin/soybean lecithin/hydrogenated lecithin, 12% ganoderma lucidum extract, 8% alpine leontopodium extract, 1% sunflower seed oil, 3% aloe vera extract, 0.5% butylene glycol, 0.5% isoprene glycol, 0.01% carbomer, 0.01% xanthan gum, 0.01% triethanolamine, balance water, in weight percent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311539127.6A CN117462427A (en) | 2023-11-17 | 2023-11-17 | A nutritional composition for improving periocular skin fine wrinkles by ultrasound or radio frequency |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311539127.6A CN117462427A (en) | 2023-11-17 | 2023-11-17 | A nutritional composition for improving periocular skin fine wrinkles by ultrasound or radio frequency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117462427A true CN117462427A (en) | 2024-01-30 |
Family
ID=89623670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311539127.6A Pending CN117462427A (en) | 2023-11-17 | 2023-11-17 | A nutritional composition for improving periocular skin fine wrinkles by ultrasound or radio frequency |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117462427A (en) |
-
2023
- 2023-11-17 CN CN202311539127.6A patent/CN117462427A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102265730B1 (en) | cosmetic composition for skin wrinkle improvement and whitening facial skin | |
| CN108113914B (en) | Essence cream without essence and preservative and preparation method thereof | |
| CN107296764B (en) | Cream and preparation method thereof | |
| CN114848541A (en) | Anti-aging and wrinkle-removing composition and preparation method thereof, and cosmetic and preparation method thereof | |
| CN107693456A (en) | A kind of natural tea pasta frost and preparation method thereof | |
| CN111467271A (en) | Skin care product containing acetylated hyaluronic acid | |
| CN113768853B (en) | Whitening and freckle-removing composition, and preparation method and application thereof | |
| CN108309923A (en) | Whitening spot-eliminating composition and preparation method thereof | |
| CN112120949B (en) | Water-light moisturizing essence and preparation method thereof | |
| CN112438905B (en) | Moisturizing and skin-brightening composition and application thereof | |
| CN113041174A (en) | Camellia seed oil essence containing hydrolyzed vegetable protein and preparation method and application thereof | |
| CN110801516A (en) | Eye nutrient spray liquid and preparation method thereof | |
| CN114288201B (en) | Composition for removing pouch and fading black eye, and preparation method and application thereof | |
| CN110559227A (en) | Skin cream for preventing and repairing striae gravidarum and preparation method thereof | |
| CN117462427A (en) | A nutritional composition for improving periocular skin fine wrinkles by ultrasound or radio frequency | |
| CN108578297A (en) | A kind of compounding moisturizing sun cream and preparation method thereof | |
| CN114159333A (en) | Muscle foundation liquid and preparation method thereof | |
| CN114010551A (en) | Moisturizing composition, application thereof and toning lotion | |
| CN113546153A (en) | Anti-aging composition capable of activating cells and preparation method thereof | |
| CN109350576B (en) | Composition with moisturizing effect and application thereof, toning lotion and preparation method thereof | |
| CN113368003A (en) | Composition with overnight muscle repairing effect and preparation method and application thereof | |
| CN112656742A (en) | Grape seed red wine mask paste and preparation method thereof | |
| CN114831915B (en) | Moisturizing and repairing eye cream and preparation method thereof | |
| CN111728919A (en) | Firming and wrinkle-removing essence and preparation method thereof | |
| CN111437220B (en) | Camellia oil fatty acid ester composition and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |