CN117427142B - 一种补血益气、调经养颜的组合物及其制备方法 - Google Patents
一种补血益气、调经养颜的组合物及其制备方法 Download PDFInfo
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- CN117427142B CN117427142B CN202311636239.3A CN202311636239A CN117427142B CN 117427142 B CN117427142 B CN 117427142B CN 202311636239 A CN202311636239 A CN 202311636239A CN 117427142 B CN117427142 B CN 117427142B
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Abstract
一种补血益气、调经养颜的组合物及其制备方法,所属药品、保健品技术领域,组合物含有红参、人参肽、速溶荜茇粉、黑生姜、角豆提取物、槲皮素、甘蔗多酚、银耳多糖、燕窝肽、植物甾醇酯等诸多成分,配合使用能够大幅提高免疫力,在补血益气、调经养颜方面具有高效、显著的疗效,并且无需饮食忌口,2个月的疗程,综合治愈率在81.3%;加入香芹酮和丁香酚提高芳香气味,并采用淀粉膜包衣,保留长久芳香气味、口感好,食用依从性高。
Description
技术领域
本发明属于药品、保健品技术领域,具体涉及一种补血益气、调经养颜的组合物及其制备方法。
背景技术
气血虚就是气虚无力,血虚发燥,气虚不能生血;气血虚的人群通常体质都比较虚弱,身体免疫力也比较低下,特别容易生病,且久病不愈;气血两虚会使气血不能上达于人的面部以及舌体,常见到面色淡白或者萎黄,舌体淡嫩;经常会出现乏力自汗、少气懒言、头晕目眩、面色淡白、心悸、失眠、怕寒、怕冷、脉细弱等症状;对于女性来说,还会发生月经不调的症状。
造成气血亏虚的原因主要有以下几个方面:1、过于劳累,劳心和劳力都会造成气血消耗,导致身体的虚弱;2、熬夜,睡眠不充足,良好的睡眠能够使脏腑能够得到休息,特别是肝脏是一个重要的养血器官,长期睡眠不充足,会造成人体的气血的亏虚,特别是血虚;3、久座,缺乏锻炼,也会出现气血的亏虚;4、受寒也会导致身体气血的不足,无论是多食冷饮、凉性食物,或者是多吹空调,冬季穿衣少薄,都会造成人体的阳气亏虚,气血的不足。女性非常容易发生月经失调的问题,月经失调表现为月经周期或出血量的异常,可伴月经前、经期时的腹痛及全身疼痛症状,严重者能够引起不孕以及严重影响身心健康。
气血两亏、月经不调的症状,通常是采用中药调理,如中药汤药、中药药丸等,通常存在调理进度慢,见效微,忌口,药物适口性差,用药依从性差的问题,且汤药煎煮麻烦,较少有人能够长期的坚持服用。
发明内容
针对现有中药调理存在的进度慢,见效微,忌口,用药依从性差,难以长期坚持服用的问题。本发明提供一种补血益气、调经养颜的组合物及其制备方法,采用红参、人参肽、速溶荜茇粉、黑生姜、角豆提取物、槲皮素、甘蔗多酚、银耳多糖、燕窝肽、植物甾醇酯等诸多成分,配合使用能够大幅提高免疫力,在补血益气、调经养颜方面具有高效、显著的疗效,并且无需饮食忌口;加入香芹酮和丁香酚提高芳香气味,并采用淀粉膜包衣,保留长久芳香气味、口感好,食用依从性高。其具体技术方案如下:
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参1份~3份、人参肽0.5份~2份、速溶荜茇粉2份~5份、黑生姜0.05份~0.2份、角豆提取物1份~3份、槲皮素0.5份~1.5份、甘蔗多酚0.5份~1.5份、银耳多糖1份~3份、燕窝肽0.5份~3份、植物甾醇酯1份~3份、香芹酮0.01份~0.05份、丁香酚0.01份~0.03份。
上述技术方案中,所述角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加水,煎煮,过滤,取滤液,浓缩至密度1.3g/mL~1.5g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入水中,在70℃~80℃混合均匀,然后降温至50℃~55℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,恒温静置,之后降温至38℃~40℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在负压条件下,烘干浓缩,切片,淀粉膜包衣,得到膏方产品。
上述制备方法的S1中,所述水的添加量为红参和黑生姜质量总和的5倍~6倍。
上述制备方法的S1中,所述煎煮温度为100℃以上。
上述制备方法的S1中,所述煎煮时间为2h~3h。
上述制备方法的S2中,所述水的质量为参姜提取液、速溶荜茇粉、角豆提取物和槲皮素总质量的2倍~4倍。
上述制备方法的S2中,所述恒温静置的温度为50℃~55℃,时间为1h~2h。
上述制备方法的S3中,所述所述负压为-0.05MPa~-0.2MPa;所述烘干浓缩温度38℃~40℃。
上述制备方法的S3中,所述烘干浓缩温度38℃~40℃。
上述制备方法的S3中,所述切片规格为,30mm×20mm×3mm。
本发明的一种补血益气、调经养颜的组合物及其制备方法,与现有技术相比,有益效果为:
一、红参和人参肽具有大补元气,益气摄血、改善血液循环、抵抗疲劳和增强免疫力等功效,能有效改善体质,防止女性妇科炎症的反复。
二、荜茇具有温胃散寒、减轻腹痛症状、同时加速血液流动、维持寒冷环境下正常血液循的作用,特别用于治妇人血气不和,疼痛不止,及下血无时,月水不调。荜拨还有降高血脂作用,荜茇提取物中的胡椒碱甲脂能有效降低血脂水平,另外,荜茇能加速血液流动,扩张血管,具有散寒的作用。
三、黑生姜具有增强精力,强壮滋养的功效,能够改善血液流动,增强活力等。其中,黑姜聚甲氧基黄酮是黄酮类的多酚类化合物,能够减少内脏脂肪和皮下脂肪,加速日常活动中的能量消耗,促进新陈代谢。
四、角豆提取物中含有D-手性肌醇,是DCI胰岛素信号流程中的二级信使,胰岛素敏化剂,能够降低胰岛素抵抗,胰岛增敏,起到多种生理功能,比如:降血糖、改善多囊卵巢综合征(PCOS)、抗氧化、抗衰老等作用。DCI能欧改善排卵功能,调节女性LH与胰岛素分泌及内分泌。
五、槲皮素是自然界广泛存在的黄酮类化合物,具有抗炎、提高免疫力的作用。
六、甘蔗多酚具有抗氧化、抗衰老的作用,还能够控制血糖水平和降低高碳水化合物食物的血糖指数。
七、银耳多糖具有调节提高免疫的作用,能够诱导的脾淋巴细胞增殖反应,增强免疫功能。银耳多糖还具有抗衰老功效,银耳多糖促进核酸及蛋白质的合成、增加肝微粒体细胞色素P-450含量,增强机体免疫功能而发挥抗衰老作用。另外,银耳多糖还具有降血糖作用、降血脂作用、促进蛋白质、核酸合成、抗凝血、抗血栓作用、抗溃疡作用、抗突变作用。
八、燕窝肽能够维持皮肤健康、免疫调节、增强免疫力、调节血压和提高代谢速率,且具有调节神经功能紊乱、改善骨质疏松的作用。
九、植物甾醇酯对成纤维细胞具有增生效果,促进胶原蛋白的产生,对黑色素细胞具有抑制作用,还具有紫外线保护,保湿,抗氧化,抗炎,生发等作用,能够调节皮肤达到健康状态,防止皮肤老化,改善皮肤弹性和色泽,降低皮肤粗糙度。
十、香芹酮和丁香酚具有良好的芬芳气味,改善膏方气味,提高食用依从性。
十一、针对配方成分特性设计了制备方法,其中,在50℃~55℃加入香芹酮,能够长效的综合姜成分的刺激味道,改善膏体整体气味。最后在38℃~40℃加入丁香酚促进膏方香味,且不易散发流失,防止过早加入影响膏方气味变淡。
十二、本发明组合物制备成膏方切片,淀粉膜包衣,一方面切片便于食用,无需用户自己进行切割,防止把握不好用量。另一方面淀粉膜包衣能够保证芳香气味的长久保持,且食用时拿取方便,不会互相黏连,食用时也不易粘牙。
综上,本发明配方中综合了红参、人参肽、速溶荜茇粉、黑生姜、角豆提取物、槲皮素、甘蔗多酚、银耳多糖、燕窝肽、植物甾醇酯、香芹酮和丁香酚诸多成分,各种成分配合使用,能够大幅提高免疫力,在补血益气、调经养颜方面具有高效、显著的疗效,口感好,食用依从性高,并且无需饮食忌口;2个月的疗程,综合治愈率在81.3%。
具体实施方式
下面结合具体实施案例对本发明作进一步说明,但本发明并不局限于这些实施例。
实施例1
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参2份、人参肽1份、速溶荜茇粉3.5份、黑生姜0.1份、角豆提取物2份、槲皮素1份、甘蔗多酚1份、银耳多糖2份、燕窝肽2份、植物甾醇酯2份、香芹酮0.03份、丁香酚0.02份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加5.5倍质量的水,100℃以上煎煮2.5h,过滤,取滤液,浓缩至密度1.4g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入3倍质量的水中,在75℃混合均匀,然后降温至52℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,52℃恒温静置1.5h,之后降温至39℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.1MPa的负压条件下,39℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实施例2
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参1份、人参肽2份、速溶荜茇粉2份、黑生姜0.2份、角豆提取物1份、槲皮素1.5份、甘蔗多酚0.5份、银耳多糖3份、燕窝肽0.5份、植物甾醇酯3份、香芹酮0.01份、丁香酚0.03份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加5倍质量的水,100℃以上煎煮3h,过滤,取滤液,浓缩至密度1.3g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入4倍质量的水中,在70℃混合均匀,然后降温至55℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,55℃恒温静置2h,之后降温至38℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.2MPa的负压条件下,38℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实施例3
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参3份、人参肽0.5份、速溶荜茇粉5份、黑生姜0.05份、角豆提取物3份、槲皮素0.5份、甘蔗多酚1.5份、银耳多糖1份、燕窝肽3份、植物甾醇酯1份、香芹酮0.05份、丁香酚0.01份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加6倍质量的水,100℃以上煎煮2h,过滤,取滤液,浓缩至密度1.5g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入2倍质量的水中,在80℃混合均匀,然后降温至50℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,50℃恒温静置1h,之后降温至40℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.05MPa的负压条件下,40℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实施例4
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参1份、人参肽0.5份、速溶荜茇粉2份、黑生姜0.05份、角豆提取物1份、槲皮素0.5份、甘蔗多酚0.5份、银耳多糖1份、燕窝肽0.5份、植物甾醇酯1份、香芹酮0.01份、丁香酚0.01份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加5倍质量的水,100℃以上煎煮2h,过滤,取滤液,浓缩至密度1.3g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入2倍质量的水中,在70℃混合均匀,然后降温至50℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,50℃恒温静置1h,之后降温至38℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.05MPa的负压条件下,38℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实施例5
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参3份、人参肽2份、速溶荜茇粉5份、黑生姜0.2份、角豆提取物3份、槲皮素1.5份、甘蔗多酚1.5份、银耳多糖3份、燕窝肽3份、植物甾醇酯3份、香芹酮0.05份、丁香酚0.03份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加6倍质量的水,100℃以上煎煮3h,过滤,取滤液,浓缩至密度1.5g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入4倍质量的水中,在80℃混合均匀,然后降温至55℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,55℃恒温静置2h,之后降温至40℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.2MPa的负压条件下,40℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实施例6
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参1.2份、人参肽0.8份、速溶荜茇粉2.5份、黑生姜0.08份、角豆提取物1.2份、槲皮素0.8份、甘蔗多酚0.8份、银耳多糖1.2份、燕窝肽0.8份、植物甾醇酯1.2份、香芹酮0.02份、丁香酚0.02份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加5.2倍质量的水,100℃以上煎煮2h,过滤,取滤液,浓缩至密度1.3g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入2.5倍质量的水中,在72℃混合均匀,然后降温至52℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,52℃恒温静置1h,之后降温至38.5℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.07MPa的负压条件下,38.5℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实施例7
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参2.5份、人参肽1.5份、速溶荜茇粉4份、黑生姜1.5份、角豆提取物2.5份、槲皮素1.2份、甘蔗多酚1.2份、银耳多糖2.5份、燕窝肽2.5份、植物甾醇酯2.5份、香芹酮0.04份、丁香酚0.04份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加5.8倍质量的水,100℃以上煎煮3h,过滤,取滤液,浓缩至密度1.5g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入4倍质量的水中,在78℃混合均匀,然后降温至54℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,54℃恒温静置2h,之后降温至39.5℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.15MPa的负压条件下,39.5℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实施例8
一种补血益气、调经养颜的组合物,原料组成质量份数包括:红参1.2份、人参肽1.5份、速溶荜茇粉2.5份、黑生姜1.5份、角豆提取物1.2份、槲皮素1.4份、甘蔗多酚0.8份、银耳多糖2.5份、燕窝肽1份、植物甾醇酯2.5份、香芹酮0.03份、丁香酚0.02份。其中,角豆提取物为角豆的乙醇溶剂提取物。
上述一种补血益气、调经养颜的组合物的制备方法,包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加5.5倍质量的水,100℃以上煎煮2.5h,过滤,取滤液,浓缩至密度1.5g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入3.5倍质量的水中,在75℃混合均匀,然后降温至55℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,55℃恒温静置1.5h,之后降温至40℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物。
S3,浓缩:
将混合物在-0.1MPa的负压条件下,40℃烘干浓缩,切片成30mm×20mm×3mm规格的薄片,淀粉膜包衣,得到膏方产品。
实验一、分别采用实施例1至实施例8的组合物(S2中得到组合物,浓缩成密度0.8g/mL)进行小鼠痛经模型的止痛实验。选取80只实验小鼠,随机分为8组,每组10只,分别对应服用实施例1至实施例8,小鼠连续灌胃给予相应组合物,每次0.5mL;对照组给予等量生理盐水灌胃处理(10只小鼠);每天两次,共灌胃5天,5天后最后一次给药30min小时后,对每只实小鼠腹腔注射0.2mL/kg质量浓度为0.35%的醋酸,尾尖0.5cm处断尾,记录40min内小鼠疼痛的扭体次数,如下表所示:
组合物 | 总扭体次数(次) | 平均扭体次数(次) |
实施例1组合物 | 143 | 14.3 |
实施例2组合物 | 136 | 13.6 |
实施例3组合物 | 142 | 14.2 |
实施例4组合物 | 152 | 15.2 |
实施例5组合物 | 146 | 14.6 |
实施例6组合物 | 134 | 13.4 |
实施例7组合物 | 138 | 13.8 |
实施例8组合物 | 145 | 14.5 |
对照组 | 326 | 32.6 |
实验结果可知,实施例1至实施例8的组合物均对镇痛有明显效果。
实验二、分别采用实施例1至实施例8的组合物(S2中得到组合物,浓缩成密度0.8g/mL)进行小鼠痛经模型的补血益气实验。选取90只实验小鼠,小鼠眼眶采血,300mg/kg,测定正常血象值,随机分为9组,每组10只,分别对应服用实施例1至实施例8,以及对照组。在小鼠眼眶后静脉丛连续放血七天,每天0.5mL,造成急性失血性血虚模型,然后灌胃给药,每天两次,每次0.5mL,对照组灌胃等量的生理盐水;连续给药7天后,小鼠眼眶采血300mg/kg,测定血象值,包括血液中红细胞(RBC)、血红蛋白(HGB)、红细胞压积(HCT)、血小板计数(PLT)和白细胞(WBC)的值,采血后制成抗凝全血样本,置于血细胞分析仪测定;测定结果的平均值如下表所示:
实验三、人体试用实验,选择80名气血两亏、肝肾阴虚、月经不调(有痛经和经期不规律)的女性受试者(22岁至42岁),分成8组,分别食用实施例1至实施例8的膏方产品,每天早、晚各食用一片(单片规格30mm×20mm×3mm),服用2个月,记录结果如下表所示:
治愈表现为:经量与经期紊乱、疲劳乏力、面色萎黄(气血两亏、肝肾阴虚)症状全部消失,痛经减轻或全无。
症状减轻表现为:经量与经期接近正常、痛经改善,疲劳乏力、面色萎黄(气血两亏、肝肾阴虚)改善。
受试者评价:适口性良好,有香甜味,食用无刺激感,用药依从性良好。治疗结果表明,膏方产品对气血两亏、肝肾阴虚、月经不调具有良好的疗效,见效快,30天有明显减轻,疗效好,60天后治愈率高,两个月的综合治愈率在81.3%。
Claims (9)
1.一种补血益气、调经养颜的组合物,其特征在于,组合物由如下质量份数的原料制成:红参1份~3份、人参肽0.5份~2份、速溶荜茇粉2份~5份、黑生姜0.05份~0.2份、角豆提取物1份~3份、槲皮素0.5份~1.5份、甘蔗多酚0.5份~1.5份、银耳多糖1份~3份、燕窝肽0.5份~3份、植物甾醇酯1份~3份、香芹酮0.01份~0.05份、丁香酚0.01份~0.03份;
所述角豆提取物为角豆的乙醇溶剂提取物。
2.权利要求1所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,方法包括如下步骤:
S1,备料:
按质量份数,将红参和黑生姜进行粉碎,添加水,煎煮,过滤,取滤液,浓缩至密度1.3g/mL~1.5g/mL的参姜提取液;
S2,混合:
按质量份数,将参姜提取液、速溶荜茇粉、角豆提取物和槲皮素加入水中,在70℃~80℃混合均匀,然后降温至50℃~55℃恒温,加入甘蔗多酚、银耳多糖和香芹酮进行混合均匀,恒温静置,之后降温至38℃~40℃恒温,加入燕窝肽、人参肽、植物甾醇酯和丁香酚进行混合均匀,得到混合物;
S3,浓缩:
将混合物在负压条件下,烘干浓缩,切片,淀粉膜包衣,得到膏方产品。
3.根据权利要求2所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,S1中,所述水的添加量为红参和黑生姜质量总和的5倍~6倍。
4.根据权利要求2所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,S1中,所述煎煮的温度为100℃以上。
5.根据权利要求2所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,S1中,所述煎煮的时间为2h~3h。
6.根据权利要求2所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,S2中,所述水的质量为参姜提取液、速溶荜茇粉、角豆提取物和槲皮素总质量的2倍~4倍。
7.根据权利要求2所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,S2中,所述恒温静置的温度为50℃~55℃,时间为1h~2h。
8.根据权利要求2所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,S3中,所述所述负压为-0.05MPa~-0.2MPa;所述烘干浓缩温度38℃~40℃。
9.根据权利要求2所述的一种补血益气、调经养颜的组合物的制备方法,其特征在于,S3中,所述切片规格为,30mm×20mm×3mm。
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WO2021120972A1 (zh) * | 2019-12-17 | 2021-06-24 | 四川新绿色药业科技发展有限公司 | 一种治疗气血两虚症候的中药组合物及其制备方法和应用 |
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