CN1174023A - Aloe cosmetics series prepared with aloe as main material - Google Patents

Aloe cosmetics series prepared with aloe as main material Download PDF

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Publication number
CN1174023A
CN1174023A CN 97100545 CN97100545A CN1174023A CN 1174023 A CN1174023 A CN 1174023A CN 97100545 CN97100545 CN 97100545 CN 97100545 A CN97100545 A CN 97100545A CN 1174023 A CN1174023 A CN 1174023A
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Prior art keywords
aloe
aloe gel
grams
gel
essence
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Granted
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CN 97100545
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Chinese (zh)
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CN1073408C (en
Inventor
孙宇梅
李涵
张小华
焦玉英
董银卯
华伟
马洁峰
王瑶
李瑞强
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Beijing Technology and Business University
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Haikou Tech Industrial And Trade Development Co Beijing Light Industrial Coll
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Priority to CN97100545A priority Critical patent/CN1073408C/en
Publication of CN1174023A publication Critical patent/CN1174023A/en
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Publication of CN1073408C publication Critical patent/CN1073408C/en
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Expired - Fee Related legal-status Critical Current

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  • Cosmetics (AREA)

Abstract

The aloe cosmetic series includes various cosmetics of different preparation form, which are prepared by using aloe gel products, including decolored or un-decolored aloe gel liquid with biological activity maintained, decolored or un-decolored condensated aloe gel liquid, decolored or un-decolored aloe gel powder or aloe oil, as main material and compounding with proper amount of cosmetic matrix. It has an aloe gel content of 50-99 and thus ideal effect.

Description

With the aloe is the aloe cosmetics series prepared of primary raw material
Aloe has use value and economic worth as a kind of ancient plant, and the applicating history of Aloe aspect Chinese Medicine is long, all takes much count of aloetic research in developed countries such as the U.S., Japan at present, development and utilization work.Through years of researches, find that Aloe inner gel matrix contains abundant aloin, polysaccharide, organic acid, protein, polypeptide, free amino acid and multivitamin, trace element, specific function active ingredients such as multiple enzyme and steroid.These active ingredients make Aloe have very strong Premeabilisation of cells ability and hypoallergenic drug effect.Thereby Aloe gel is that the natural penetrating agent of human body skin, epidermis cell promote wetting agent, cell growth stimulant.Its active ingredient, have antiinflammatory, sterilization, sun-proof, uvioresistant through the various clinical checking, anticorrosion, ulcer and hemostatic treatment function, the multiple nutrients composition that it contains has the effect of skin nutrition, hair care, hair growth promoting, it has multiple natural organic component is the natural wetting agent of skin, the multiple active ingredient that it contains collaborative produced and had immunity and immunoloregulation function, free radical resisting, antiendotoxin function.
One of people's body and major reason of cell senescence are because physiology or non-physiologic factor (as disease) bring out the cumulative bad damage of the long-term chronic progressive external of free radical.And radical damage accounts for very most is the damage of superoxide radical.The just free oxygen of superoxide radical (perhaps claiming active oxygen) is to the damage maximum of skin and blood circulation, and Here it is causes old and feeble main cause.Skin occurs coarse, wizened and wrinkly, matt and follows the string even senile plaque occurs, the wearing out of Here it is skin.Superoxide radical is under the catalytic action of super oxygen dismutase (SOD) in the organism, and disproportionation is H 2O 2And O 2And H 2O 2Under the catalase effect, be decomposed into H 2O and O 2, the reason of Here it is super oxygen dismutase (SOD) can eliminate superoxide radical.The super oxygen dismutase that Aloe gel contains contains catalase, V with it A, V B, cysteine and a large amount of active ingredients such as trace element down collaborative can make superoxide radical disproportionation, sealing.Thereby eliminated body and the cells injury of superoxide radical, reached anti-aging purpose the people.A large amount of clinical showing, Aloe also is that Aloe is brought into play one of antidotal reason to the protective effect of bone marrow and extramedullary hemopoiesis system.
Aloe has shown the effect of health care and raise immunity when for oral administration, the time spent can reach purposes such as beauty treatment, speckle dispelling, slow down aging outside.
The Aloe cosmetics of having invented in the world at present are many, but with regard to domestic, the Aloe cosmetics that really appear on the market are also not very a lot.Though no matter domestic, external Aloe cosmetics have certain efficient functional, and are all unsatisfactory, DeGrain.For example, on October 31st, 1984 disclosed GB-2138, the 679A patent, Aloe juice (1: 1) consumption is 0.75%; January 18 nineteen eighty-three disclosed USP4,369,180 patents, Aloe juice (1: 1) consumption is 25%; On April 1st, 1987 disclosed USP4,656,029 patents, the Aloe extract consumption is 0.5-20%; On July 2nd, 1988, JP63-159304 patent Aloe consumption is 0.2-0.5%; December in 1989 the flat 1-301610 Aloe of JP on the 5th consumption is 0.2-5%, July 31 nineteen ninety, the flat 2-193908 of JP etc. has introduced Aloe gel or aloetic extract is applied in cosmetics, but in these technology aloetic use amount only is limited in " assisting " raw material range, just use amount is all fewer.Certainly, people also find various curative effects, the effect of Aloe cosmetics, with its addition, have one " dose-effect " relation.From effective formulation analysis, be cosmetics, the skin care item of primary raw material with the Aloe, the Aloe gel addition that used 1: 1 reaches 20-50% substantially, sunscreen product, addition is higher.Hei Jiersi reminds in this product Aloe content must reach the aloetic drug effect competence exertion of 50-80% to come out.
In view of present cosmetics, with the Aloe be primary raw material also seldom, the aloe that the objective of the invention is to be to provide a kind of preparation be primary raw material the aloe cosmetics series prepared of obvious curative effects arranged.
The present invention relates to a kind of is the serial cosmetics of primary raw material with the aloe, it is characterized in that using Aloe gel system raw material, is equipped with the basic substrate of appropriate cosmetics, produces and is rich in aloetic serial cosmetics.
Its Aloe gel goods can use the Aloe gel stock solution (1: 1) that keeps bioactive decolouring or no bleaching; The aloe gel concentrate (10: 1) (20: 1) of decolouring or no bleaching; The Aloe gel dry powder and the aloe of decolouring or no bleaching.What be equipped with that suitable cosmetic base makes various different dosage forms is the aloe cosmetics series prepared of primary raw material with the aloe again, makes the content of Aloe gel (1: 1) reach ideal effect at 50-99%.
The invention provides the prescription that an aloe gel content reaches 98% skin cream, the product of this prescription has good use characteristic, skin care, keep skin not have dry sensation, preserve moisture, can make moisture content be penetrated into epidermis cell, promote the microcirculation of blood, make the skin high resilience, reach the effect of moistening skin.
The prescription of Aloe skin cream of the present invention is as follows:
Weight ratio
Decolored aloe gelin proportion glue (1: 1) 98%
* carbopol 940 0.8%
Triethanolamine 99% 0.2%
Triumphant loose Kathon (CG) 0.1%
Glycerol 0.9%
* carbopol 940 is a U.S. Goodrich company product
Embodiment 1:
The preparation method of Aloe skin cream is as follows: add decolored aloe gelin proportion glue (1: 1) 980 grams in the beaker of 2000ml, be heated to the 30-40 degree slightly and add 8 gram carbopol 940, with 90 rev/mins of stirrings, make it to dissolve fully.After stopping heating, slowly add neutralization, keep simultaneously stirring about 20 minutes with 2 gram triethanolamine.Thick shape is colourless to utilize transparent liquid to forming, and the Kathon (CG) of 90 gram glycerol and 1g is added all easily stir.Obtain 98% Aloe gel skin cream, 1000 grams.
Embodiment 2:
The preparation method of Aloe skin cream again can be as follows: add the 880g deionized water in the 2000ml beaker, be heated to the 30-40 degree slightly, add the 8g carbopol 940, with 90 rev/mins of speed stirring and dissolving, with 100g aloe gel concentrate (10: 1), 10g glycerol joins in the beaker, after stirring, stop heating, be neutralized to into thick liquid with the 2g triethanolamine, add 1gKathon (CG) again, stir.Obtain 98% Aloe skin cream, 100 grams.
The invention provides a prescription that contains the mild shampoo of aloe gel more than 50%, it is characterized in that containing:
Contain the aloe gel (1: 1) more than 50% or 50%
The 4-17% anion surfactant is arranged approximately.
The fatty diglycollic amide that 0.5-6% is arranged approximately.
The alkyl betaine of 0.5-6% or the betanin of modification are arranged approximately.
The pantothenylol that 0.01-2% is arranged approximately, pruritus or silicone oil.
The present invention requires anion surfactant in the mild shampoo, should be with aliphatic alcohol or fatty alcohol-polyoxyethylene ether (AEO 3) sulphuric acid triethanolamine salt or ammonium salt.Such anion surfactant has abundant foam and extremely low zest.
Mild shampoo selects for use aloe gel concentrate to make shampoo, so that improve aloetic content in the shampoo, in the hope of reaching aloetic effect.
The prescription of Aloe shampoo of the present invention is as follows:
Weight ratio dodecyltriethanolamine sulfate (40%) 15% fatty alcohol-polyoxyethylene ether (AEO 3) an amount of anticorrisive agent 0.1% essence of 6%10: 1 aloe gel concentrates (decolouring) 7%6501 (fatty diglycollic amide) of ammonium sulfate (25%) 25%4401 (amide betaine), 4% antipruritic, 0.1% pearlite slurry, 1% citric acid 0.1% deionized water 41.6%
Embodiment 3:
The preparation method of mild shampoo is as follows:
In the beaker with 2000ml, add the deionized water of 410g, add 150g dodecyltriethanolamine sulfate and 250g fatty alcohol-polyoxyethylene ether (AEO again 3) ammonium sulfate, be heated to 70 degree, stir with 60 rev/mins of speed and dissolve fully, add 4401 60g more respectively, 650140g after stirring and dissolving is complete, is cooled to the 30-40 degree, after adding 70g decolored aloe gel concentrated solution (10: 1) stirs, add pruritus 1g again, fully be dissolved to transparent.The reuse citric acid is regulated PH to 5-6.Treat that the stable back of pH value adds Pearl Concentrate, slowly stir (mixing speed is 50 rev/mins) simultaneously, add essence 1g, after antiseptic Kathon (CG) 1g stirs a little, left standstill 24 hours.Obtain soft type Aloe shampoo 1000g.
Example 4:
A kind of Aloe content reaches the preparation method of the shampoo more than 95%.
The 430g deionized water is placed the 2000ml beaker, successively add ammonium lauryl sulfate (25%) 150g; Fatty alcohol-polyoxyethylene ether (AEO3) ammonium sulfate (25%) 200g and 650150g; CAB 40g heat to 70 degree stirs with 60 rev/mins of speed, and it is dissolved fully.To be cooled when 30-40 spends, add decolored aloe gel concentrated solution (10: 1) 95g; Pantothenylol 10g, pruritus 10g, silicone oil 10g stirs, and it is transparent that it is dissolved to fully.Regulating pH value with citric acid is 5-6.Add Pearl Concentrate 10g, essence 1g, antiseptic Kathon (CG) 1g and pigment stir with 50 rev/mins of speed, leave standstill 24 hours.Obtain 95% Aloe shampoo, 1000 grams.
The feature of this example is to have very good clean result, and easily flushing when carding property is good, owing to used high-load Aloe gel to be equipped with water-soluble silicon oil, makes hair be rich in gloss, elegant together.The collaborative of Aloe and pantothenylol arranged simultaneously, can be nutritious, repair the effect of hair, be high-grade shampoo.
The invention provides that a kind of to contain having of aloe gel antipruritic, the prescription of the floral water of inflammation-diminishing function is characterized in that
The aloe gel that 50%-80% is arranged approximately.
The ethanol that 60-80% is arranged approximately.
The wetting agent that 2-10% is arranged approximately
The present invention requires to prepare high-load Flos Aloe dew, should guarantee the basic demand of floral water, ethanol content 70-75%, between the essence consumption 2-5% outside, simultaneously make the content of Aloe gel reach 50-80% again, thereby should select aloe gel concentrate or Aloe gel dry powder for use.
Embodiment 5: a kind of Aloe content is up to 70% Flos Aloe dew.
The prescription of Flos Aloe dew is as follows:
Percentage by weight
Ethanol (95%) 70
Glycerol 2
Butanediol 3
Aloe gel concentrate (10: 1) (decolouring) 7
Methyl hydroxybenzoate 0.5
Essence 3
Citric acid 0.01
Citric acid receives 0.1
Pigment 0.01
Deionized water 14.38%
The preparation method of Flos Aloe dew is as follows:
1, with adding 95% the ethanol of 350g in the 70g decolored aloe gel concentrated solution (10: 1), after stirring, left standstill one month, after filtration, get clear liquid.
2, at room temperature, dissolve in the ethanol of 350g and stir, leave standstill, the ethanol liquid of Aloe gel is poured into, add 20g glycerol and 30g 1-3 butanediol again, stir Aloe essence 30g.
3, pigment 0.1g dissolves in the deionized water of 143g, and dissolving back and filtration add filtrate in the above-mentioned solution, evenly stir.
4, above-mentioned solution leaves standstill through 15 days ageing.
5, the ageing floral water being refrigerated to 5-10 ℃ kept 12 hours.
6, the change dew after ageing adds the 10g magnesium carbonate, after the mixing, must not surpass 2kg/cm with plate and frame type filter-press filter pressing maximum pressure 2Filtrate through filter pressing can be filtered once more.The filter pressing temperature should remain on below 10 ℃.According to said method, can prepare content and reach 70% Flos Aloe dew, 1000 grams.
The invention provides a kind of preparation method and prescription of Aloe typing hair moisturizer, it is characterized in that selecting for use water-soluble silicon oil and pantothenylol to come gloss hair and renovation agent, add high-load Aloe gel simultaneously, improve its nutrition, gloss and reparation effect, use advanced molding resin simultaneously, make hair keep moulding.Its principal character is: (1) contains the about 5-9% of aloe gel concentrate (10: 1).(2) contain the about 4-10% of DC193.(3) contain the about 1-3% of 755N.
The prescription of Aloe typing hair moisturizer is as follows:
Weight ratio
DC193 6%
755N 1%
Aloe gel concentrate (10: 1) 5%
Glycerol 5%
TX-10 0.5%
Fragrant 0.1%
Pantothenylol 1%
EDTA 0.1%
Kathon?CG 0.06%
Deionized water 81.4%
Aloe typing hair moisturizer preparation method is as follows:
The deionized water that adds 814g in the 2000ml beaker is heated to the 80-90 degree, add 10g 755N, glycerol 50g stirring and dissolving to transparency liquid, be cooled to 40 degree, add aloe gel concentrate (10: 1) 50g again, add DC193 60g and Kathon (CG) 0.6g.TX-105g in the 150ml beaker adds essence 1g in evenly stirring, and behind the mix homogeneously, adds in the above-mentioned Aloe solution fully again, adds pantothenylol 10g, EDTA1g again in stirring with 90 rev/mins of speed, after the dissolving all, refilters and obtains 1000g Aloe typing hair moisturizer.
The present invention requires: 755N is earlier with the ISP Gafouat 755N of company
DC193: select Dow Corning Corporation for use
TX-10: select Japanese Kao company for use
The invention provides a kind of manufacture method and prescription of cosmetics essence, it has aloe, V E, V D, the delaying decrepitude of skin that Aloe has, beauty treatment promote outside the feature of blood microcirculation, also rich abundant nutrition, and collaborative vitamin E, vitamin D, essence can make people's skin gloss, high resilience.Diastole wrinkle, skin whitening and rejuvenating and skin nutrition.The present invention is by aloe and oil-soluble V E, V Dcompositely reach splendid effect.Its principal character is: (1) contains aloe (full leaf) 50-90%.(2) contain lanoline 0.1-35%.(3) contain V E1-5%, V D1-5%.
The prescription of aloe vera highlights is as follows:
Weight ratio
Aloe 70%
Refined wool fat 25%
V E 2%
V D 2%
Propylparaben 1%
The preparation method of aloe vera highlights:
In the 200ml beaker, add the aloe of 70g, add V again E2g, V DWhen 2g stirs, add the 25g refined wool fat again, it is dissolved fully after, add the 1g propylparaben again.Evenly, leave standstill, obtain aloe vera highlights 100g.

Claims (7)

1, with the aloe be the aloe cosmetics series prepared of primary raw material, other basic substrate is in its prescription: Aloe gel, CarboqoL, triethanolamine, glycerol, anion surfactant, ester fat acid diglycollic amide, alkyl betaine or modified betaine, pantothenylol, pruritus, silicone oil, ammonium lauryl sulfate, AESA, the Aloe gel concentrated juice, Pearl Concentrate, antiseptic, essence, deionized water, refined wool fat, V E, V D, propylparaben, DC193, TX-10, EDTA, Kathon CG, citric acid, sodium citrate, pigment, ethanol, butanediol, methyl hydroxybenzoate, wetting agent, amide betaine, anion surfactant.It is characterized in that with the Aloe being primary raw material, be equipped with the basic substrate of appropriate cosmetics, produce and be rich in aloetic serial cosmetics, and its Aloe gel goods can use the decolouring of the biological property controlled of maintenance or the Aloe gel stock solution (1: 1) of no bleaching; The aloe gel concentrate (10: 1) of decolouring or no bleaching; (20: the 1) decolouring or the Aloe gel dry powder and the aloe of no bleaching, the content that makes Aloe gel (1: 1) at 50-99% to reach best effects.
2, described according to claim 1, it is characterized in that the aloe gel content reaches 98% skin cream.Decolored aloe gelin proportion glue (1: 1) wherein, 98%, CarbopoL940,0.8%, triethanolamine 99% 0.2%, glycerol 1%.
3, described by claim 1, it is characterized in that the aloe gel content reaches the mild shampoo more than 50% or 50%.It is characterized in that containing aloe gel (1: 1) more than 50% or 50% has the anion surfactant of 4%-17%, the fatty diglycollic amide that 0.5%-6% is arranged, pantothenylol, pruritus or the silicone oil of the alkyl betaine of 0.5%-6% or the betanin of modification: 0.01%-2%.Prescription is: dodecyltriethanolamine sulfate 40%, weight ratio 15%, aliphatic alcohol polyoxyethylene sulphuric acid amine 25%, 4401 (amide betaine) 6%, (10: 1) aloe gel concentrate (decolouring) 7%, 6501 (fatty diglycollic amides) 4%, pruritus 0.1%, Pearl Concentrate 1%, antiseptic 0.1%, essence 0.1%, deionized water 41.6%.
4, described by claim 1, it is characterized in that Aloe content reaches the shampoo more than 95%, its composition is ammonium lauryl sulfate 25%150 grams, aliphatic alcohol polyoxyethylene ammonium sulfate 25%200 grams, 6501,50 grams, CAB 45 grams, decolored aloe gel concentrated solution 95 grams (10: 1), pantothenylol 10 grams, pruritus 10 grams, silicone oil 10 grams, citric acid transfers to pH value 5-6, Pearl Concentrate 10 grams, essence 1 gram, antiseptic 1 gram and pigment.
5, described by claim 1, its feature can play the floral water of inflammation-diminishing function, and the aloe gel content is 50%-80%, and ethanol is 60-80%, wetting agent 2-10%.
Its prescription is: alcohol 95 %, and glycerol 2%, butanediol 3%, Aloe gel concentrates (10: 1), decolouring 7%, Methyl p-hydroxybenzoate 0.5%, essence 3%, citric acid 0.01%, sodium citrate 0.1%, pigment 0.01%, deionized water 14.38%.
6, described by claim 1, it is characterized in that with the Aloe being the Aloe typing hair moisturizer of primary raw material.Aloe gel concentrate (10: 1) 5-9%, DC193 is 4-10%, 755N is 1-3%.
Its prescription is DC1936%, and 755N 1%, aloe gel concentrate (10: 1), and 5%, glycerol 5%, TX-10 5%, essence 0.1%, pantothenylol 1%, EDTA0.1%, Kathon CG 0.06%, deionized water: 81%.
7. it is described to press claim 1, it is characterized in that being rich in the cosmetics essence of aloe.Aloe (containing leaf) oil is 50-90% refined wool fat 0.1-35%, V E1-5%, V D1-5%.
Its prescription is aloe 70%, refined wool fat 25%, V E2%, V D2%, propylparaben 1%.
CN97100545A 1997-01-30 1997-01-30 Aloe cosmetics series prepared with aloe as main material Expired - Fee Related CN1073408C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN97100545A CN1073408C (en) 1997-01-30 1997-01-30 Aloe cosmetics series prepared with aloe as main material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN97100545A CN1073408C (en) 1997-01-30 1997-01-30 Aloe cosmetics series prepared with aloe as main material

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CN1174023A true CN1174023A (en) 1998-02-25
CN1073408C CN1073408C (en) 2001-10-24

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100401057C (en) * 2005-12-08 2008-07-09 上海复星临西药业有限公司 Method for detecting aloes glucoside in compounded aloes capsule
CN101375830B (en) * 2007-08-31 2011-06-22 天津天狮生物发展有限公司 Aloe moisture-keeping nutrient skin-care cream and preparation method thereof
CN105362165A (en) * 2015-12-11 2016-03-02 登封市科创商务咨询有限公司 Aloe nutrient skin cream
CN105534768A (en) * 2015-12-11 2016-05-04 登封市科创商务咨询有限公司 Aloe mild-type shampoo
CN106109286A (en) * 2016-06-21 2016-11-16 登封市科技企业孵化服务中心 Aloe nutritional hair conditioner
CN106176368A (en) * 2016-07-28 2016-12-07 扬中市锦丰工业设计有限公司 Whitening floral water
CN106606450A (en) * 2016-12-23 2017-05-03 惠州市七分妆化妆品有限公司 Plant nutrient water
CN113069377A (en) * 2020-01-06 2021-07-06 广州樱奈儿化妆品有限公司 Anti-aging face cream and preparation method thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6908941B2 (en) * 2002-06-06 2005-06-21 Nicholas V. Perricone Hair and nail treatments using alkanolamines
CN100336472C (en) * 2004-08-05 2007-09-12 刘杰 Manufacturing method of concentrated aloe juice maintaining biological activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062087A (en) * 1991-10-30 1992-06-24 王朝文 The processing technology of new decoction
CN1028152C (en) * 1992-03-14 1995-04-12 万金志 Extraction and refining method of cosmetic and medicinal aloe

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100401057C (en) * 2005-12-08 2008-07-09 上海复星临西药业有限公司 Method for detecting aloes glucoside in compounded aloes capsule
CN101375830B (en) * 2007-08-31 2011-06-22 天津天狮生物发展有限公司 Aloe moisture-keeping nutrient skin-care cream and preparation method thereof
CN105362165A (en) * 2015-12-11 2016-03-02 登封市科创商务咨询有限公司 Aloe nutrient skin cream
CN105534768A (en) * 2015-12-11 2016-05-04 登封市科创商务咨询有限公司 Aloe mild-type shampoo
CN106109286A (en) * 2016-06-21 2016-11-16 登封市科技企业孵化服务中心 Aloe nutritional hair conditioner
CN106176368A (en) * 2016-07-28 2016-12-07 扬中市锦丰工业设计有限公司 Whitening floral water
CN106606450A (en) * 2016-12-23 2017-05-03 惠州市七分妆化妆品有限公司 Plant nutrient water
CN113069377A (en) * 2020-01-06 2021-07-06 广州樱奈儿化妆品有限公司 Anti-aging face cream and preparation method thereof

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Applicant after: Beila Aloe Development and Research Center, Beijing

Applicant before: Beijing Institute of light industry Haikou industry and Trade Industrial Development Corporation

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: HAIKOU TECHNOLOGY, INDUSTRY + TRADE INDUSTRIAL DEVELOPMENT CORPORATION, BEIJING INSTITUTE OF LIGHT INDUSTRY TO: BEIJING BEILA ALOE DEVELOPMENT AND RESEARCH CENTER

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Owner name: BEIJING TECHNOLOGY AND BUSINESS UNIEERSITY

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Effective date: 20040618

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Address after: 100037, Fu Cheng Road, Beijing, Haidian District, No. 11

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Address before: 100037, Fu Cheng Road, Beijing, Haidian District, No. 11

Patentee before: Beila Aloe Development and Research Center, Beijing

C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee