CN1028152C - Extraction and refining method of cosmetic and medicinal aloe - Google Patents

Abstract

The present invention relates to a technique for extracting and refining medicinal plant raw material, which is a method for extracting and refining aloes for cosmetics and medicines. In the present invention, various effective medicinal components in aloes are extracted by a non-solvent method as fine aloe raw materials for cosmetics and medicines. The technique comprises the following steps: scraped aloe juice is heated and precipitated, filtered aloe clear liquid is exchanged by ion exchange resin until a pH value reaches 6 to 7, and collected fine aloe juice is stored at low temperature and shielded from light. The technique of the present invention is simple and practical. The fine aloe juice can be directly used for compounding various cosmetics or used for preparing medicines as medicinal raw material. Obtained products have the advantages of little possibility of discoloration and deterioration, high safety and high reliability.

Description

Extraction and refining method of cosmetic and medicinal aloe

The present invention relates to the extraction purification techniques of medicinal plants raw material, is the extraction process for purification of a kind of cosmetics and medicinal aloe.

Aloe is a kind of very plant of high bioactivity that has, a large amount of research has been done in its Main Ingredients and Appearance pharmacological action aspect abroad over past ten years, proved that Aloe assists inflammation at treatment bacterial skin infections, furuncle and phyma, eye skin ulcer, hair, wound postoperative infection, burn, scald, there is good effect aspects such as ultraviolet burn.Particularly Aloe to the preserving moisture of skin, moisten, promote the healing of wound and damaged skin, thin fertile regenerated unique effect just is being subjected to the increasing attention of people.Aspect medical, people such as external Aryayer system have reported Aloe in the application of department of eye, internal medicine and gynecological with to the tumor treatment effect.U.S. card Islington experiment company is in the patent application of a CN89100264.2 " method for preparing aloe product ", disclose the method for extracting the polysaccharide material with pharmaceutically active from aloe plant, this method mainly is to adopt solvent method to extract more purified polysaccharide as medicinal.Domestic in recent years also the beginning researched and developed the medicinal of aloe plant and health-care effect aspect, particularly utilizes the characteristics of preserving moisture and moistening of Aloe to skin, with Aloe juice preparation skincare product and bath article etc.Because Aloe contains multiple bioactive substance, wherein there is the chemical property of part material active, when directly with Aloe juice preparing cosmetics or preparation medicine, the easy variable color of its product, even produce phenomenons such as precipitation, separation, particularly during preparing cosmetics, aloetic consumption tends to make physiologically active to disappear if surpass 2% instability if prescription is improper.Therefore for the quality that guarantees moisturizing cosmetics and the curative effect of compounding pharmaceutical, must make with extra care Aloe juice.

At the problems referred to above that exist in the prior art, the object of the present invention is to provide the extraction process for purification of a kind of cosmetics and medicinal aloe, promptly adopt non-solvent method to extract that multiple effective medicinal component can variable color, rotten with the skin protection cosmetics and the medicine that guarantee to be prepared as the refining raw material of cosmetics and medicinal aloe in the Aloe.

The present invention realizes like this: at first the fresh aloe leaf is cleaned with tap water, remove earth and surface contaminants, drain back distilled water drip washing 2-3 time, drain to such an extent that clean Folium Aloe, with the barbed part of stainless steel knife excision blade edge, along leaf flat horizontal surface horizontal direction one being broken is two, incision is towards last and be placed on the clean workbench, fixedly leaf tip or base portion are scraped pulp with stainless steel knife with mesophyll, till only staying the leaf skin.The Aloe juice that collection scrapes also places rustless steel container to heat on thermal source, under constantly stirring, be heated to closely and boil, after juice is in the state that closely boils, disconnect thermal source, add an amount of antiseptic, after stirring with its airtight cooling, after temperature is reduced to room temperature, move under refrigerator or the refrigerator-freezer low temperature (1-5 ℃) and leave standstill more than 24 hours, make it separate out post precipitation and take out, branch is got the supernatant and is filtered, after will precipitating filter pressing again its filtrate is merged sealing back cryopreservation.Also can adopt the centrifugal separation method disgorging, then with the airtight cryopreservation of Aloe clear liquid.The Aloe clear liquid that more than makes through ion-exchange treatment, treats that pH reaches 6-7 and promptly gets aloe purificata juice.The concrete grammar of ion-exchange treatment is: handle by desire the Aloe clear liquid weight 1/4～1/5 get cation exchange resin and anion exchange resin, after handling activation according to a conventional method, connect installation according to sun-male-female-cloudy four posts, crossing post with distilled water checks air tight, connect and the Aloe clear liquid for preparing previously can be added head tank after reliable or with being pumped into exchange column, control liquid outlet flow velocity is the thread shape, abandon the effusive distilled water of front end, when flowing out, collects Aloe juice, exchange several times repeatedly, the pH value of the aloe purificata juice of examine outflow reaches 6-7, reaches 140-160K Ω cm than resistance value, can collect effluent and be enclosed within the low-temperature dark preservation.The aloe purificata juice that makes by method of the present invention can be directly used in the compatibility of all kinds of cosmetics, or as the feedstock production medicine.

Compared with the prior art, aloetic extraction provided by the present invention and process for purification, simple for process, convenient and reliable operation, the compatibility of the cosmetics that the aloe purificata juice that makes can be directly used as various skin protections, also can be used as medicinal raw material and prepare medicine, and can guarantee that made product can variable color, rotten, safe and reliable.

Embodiment:

Take by weighing the Folium Aloe that 10Kg newly taps, rinse well, drain the back, drain with distilled water drip washing three times with tap water.On the workbench of cleaning, stainless steel knife with cleaning cuts Aloe limb greenbelt thorn partly, again blade is cutd open into two, section upwards along the flat horizontal surface horizontal direction, be tiled on the workbench, with the fixing leaf base of wood clamp, stainless steel knife with cleaning spreads to juice with mesophyll, up to mesophyll scrape to the greatest extent only stay the leaf skin till, collect the about 5Kg of juice that scrapes.

Collected 5Kg Aloe juice is inserted rustless steel container, and heat with the big fire of 3KW electric furnace, do not stop to stir, treat to turn down after juice closely boils the voltage cooling, keep the juice boiling for a moment, remove electric furnace, add ethylparaben 5g, fully stirring is cooled to room temperature and is placed on 1 ℃ of cryogenic conditions preservation.Take out the supernatant after three days and filter, precipitation partly adopts the way of centrifugalize to obtain clear liquid, removes the about 4.7Kg of post precipitation gained Aloe juice clear liquid.

Get 732 type cation exchange resin 1Kg, 717 type anion exchange resin 1.2Kg transfer Hydrogen and hydrogen-oxygen type respectively to after conventional pretreatment, on average are loaded on two exchange columns more respectively, connect Chengyang-male-female-Yinchiao (abdomen, Ren 7) parallel operation.The first post styletable is connected with the rustless steel water pump, whether earlier go into the exchanger inspection with distilled water through infusion leaks gas, after all are normal, adjust inlet valve, keep the water side to be after the thread shape, just the available pump Aloe juice clear liquid that will prepare is sent into exchanger, when the effusive distilled water of due-in collection outflow end reaches and checks when adding the amount of distilled water, remove and discard, formally collect the Aloe clear liquid that exchanged, after the Aloe clear liquid all flows out, again it is delivered to entrance point with clean container, carry out the exchange second time, carry out so repeatedly.After three exchanges, check that the pH value of effusive Aloe juice is about 7, reaching 150K Ω cm than resistance can collect, the about 4.7Kg of gained aloe purificata juice, and keep in Dark Place in 0 ℃ in the sealing back.The aloe purificata juice that makes like this can be directly used in various cosmetics of preparation or preparation medicine.

Claims (1)

1, the extraction process for purification of cosmetics and medicinal aloe relates to the extraction purification techniques of medicinal plants raw material, and the technology of the present invention is characterized in that:

A. clean with tap water with the fresh aloe leaf, use distilled water drip washing after removing earth and surface contaminants, drain, remove the barbed part tailing edge of blade edge blade flat horizontal surface horizontal direction and be made into two halves, mesophyll is scraped pulp and in advance to collect;

B. place the rustless steel container internal heating to closely boiling the Aloe slurry bucket of collecting, after stopping heating, add an amount of antiseptic and stir, the airtight stand at low temperature that is cooled to after the room temperature is got clear liquid and is filtered more than 24 hours, precipitation filter pressing or centrifugal back gained filtrate merge, and are enclosed within cryopreservation;

C. set by step 1/4～1/5 of (b) Aloe clear liquid weight of making get cation exchange resin and anion exchange resin is handled activation with conventional method, press sun-male-female-cloudy four posts and connect installation, cross with distilled water and again the Aloe clear liquid for preparing to be sent into exchanger after post is checked installation qualification, exchanging to the pH value that flows out the Aloe clear liquid repeatedly is 6-7, reach the aloe purificata juice that 140～160K Ω cm can collect outflow than resistance value, be enclosed within cryopreservation

Cryopreservation and dwell temperature are 1-5 ℃.