CN117377461A - 含有硝苯地平和利多卡因的局部擦拭物 - Google Patents

含有硝苯地平和利多卡因的局部擦拭物 Download PDF

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Publication number
CN117377461A
CN117377461A CN202280032680.8A CN202280032680A CN117377461A CN 117377461 A CN117377461 A CN 117377461A CN 202280032680 A CN202280032680 A CN 202280032680A CN 117377461 A CN117377461 A CN 117377461A
Authority
CN
China
Prior art keywords
wipe
concentration
topical
nifedipine
lidocaine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280032680.8A
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English (en)
Chinese (zh)
Inventor
M·斯塔尔
R·施文克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Steel Therapy Co
Original Assignee
Steel Therapy Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steel Therapy Co filed Critical Steel Therapy Co
Publication of CN117377461A publication Critical patent/CN117377461A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202280032680.8A 2021-04-01 2022-04-01 含有硝苯地平和利多卡因的局部擦拭物 Pending CN117377461A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163169768P 2021-04-01 2021-04-01
US63/169,768 2021-04-01
PCT/US2022/023130 WO2022212892A1 (en) 2021-04-01 2022-04-01 Topical wipe containing nifedipine and lidocaine

Publications (1)

Publication Number Publication Date
CN117377461A true CN117377461A (zh) 2024-01-09

Family

ID=83456873

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280032680.8A Pending CN117377461A (zh) 2021-04-01 2022-04-01 含有硝苯地平和利多卡因的局部擦拭物

Country Status (8)

Country Link
US (1) US20240156756A1 (cg-RX-API-DMAC7.html)
EP (1) EP4312984A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024512791A (cg-RX-API-DMAC7.html)
CN (1) CN117377461A (cg-RX-API-DMAC7.html)
AU (1) AU2022252406A1 (cg-RX-API-DMAC7.html)
CA (1) CA3213764A1 (cg-RX-API-DMAC7.html)
MX (1) MX2023011498A (cg-RX-API-DMAC7.html)
WO (1) WO2022212892A1 (cg-RX-API-DMAC7.html)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037886A1 (en) * 1997-02-28 1998-09-03 Carmine Antropoli Topical nifedipine preparations for the conservative treatment of functional pathologies of the anal canal
US20140256688A1 (en) * 2013-03-10 2014-09-11 Peritech Pharma Ltd. Topical compositions and methods of treatment of anorectal disorders
EP3520791A1 (en) * 2018-02-05 2019-08-07 Carmine Antropoli Nifedipine-based composition for the use in the treatment of anal fissures and proctalgya, and method for administration thereof
CN112020349A (zh) * 2018-04-25 2020-12-01 辉凌公司 用于治疗肛裂和痔疮的局部药物组合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04124128A (ja) * 1990-09-13 1992-04-24 Lion Corp 肛門部疾患治療用貼付剤
JP3012732U (ja) * 1994-12-20 1995-06-27 茂郎 槇島 痔治療の薬剤保持部材
JP2001170159A (ja) * 1999-12-19 2001-06-26 Alcare Co Ltd 緩衝能を有する接皮部材
US20040167479A1 (en) * 2003-02-20 2004-08-26 The Procter & Gamble Company Hemorrhoid treatment pad
US8377459B2 (en) * 2003-07-09 2013-02-19 The Procter & Gamble Company Composition for wet wipes that enhances the efficacy of cleansing while being gentle to the skin
PT3220924T (pt) * 2014-11-17 2022-01-12 Rev Pharma Corp Medicamento tópico para lesões da pele e mucosas associadas à epidermólise bolhosa
WO2016118040A1 (ru) * 2015-01-21 2016-07-28 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" Гель, содержащий нифедипин и лидокаина гидрохлорид, его применение и способ приготовления с использованием нанотехнологий
EA036752B1 (ru) * 2019-02-25 2020-12-16 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" Способ получения геля для ректального и наружного применения, включающего нифедипин и лидокаина гидрохлорид (варианты)

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037886A1 (en) * 1997-02-28 1998-09-03 Carmine Antropoli Topical nifedipine preparations for the conservative treatment of functional pathologies of the anal canal
US20140256688A1 (en) * 2013-03-10 2014-09-11 Peritech Pharma Ltd. Topical compositions and methods of treatment of anorectal disorders
EP3520791A1 (en) * 2018-02-05 2019-08-07 Carmine Antropoli Nifedipine-based composition for the use in the treatment of anal fissures and proctalgya, and method for administration thereof
CN112020349A (zh) * 2018-04-25 2020-12-01 辉凌公司 用于治疗肛裂和痔疮的局部药物组合物

Also Published As

Publication number Publication date
EP4312984A1 (en) 2024-02-07
MX2023011498A (es) 2024-01-17
US20240156756A1 (en) 2024-05-16
WO2022212892A1 (en) 2022-10-06
EP4312984A4 (en) 2025-02-19
AU2022252406A1 (en) 2023-11-02
CA3213764A1 (en) 2022-10-06
WO2022212892A8 (en) 2023-11-16
JP2024512791A (ja) 2024-03-19

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