CN117338670A - Toothpaste containing green pricklyash peel extract and preparation method thereof - Google Patents
Toothpaste containing green pricklyash peel extract and preparation method thereof Download PDFInfo
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- CN117338670A CN117338670A CN202311565803.7A CN202311565803A CN117338670A CN 117338670 A CN117338670 A CN 117338670A CN 202311565803 A CN202311565803 A CN 202311565803A CN 117338670 A CN117338670 A CN 117338670A
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- 239000000606 toothpaste Substances 0.000 title claims abstract description 99
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 86
- 239000000284 extract Substances 0.000 title claims abstract description 59
- 241000949456 Zanthoxylum Species 0.000 title claims abstract description 55
- 235000007650 Aralia spinosa Nutrition 0.000 title claims abstract description 52
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 238000000605 extraction Methods 0.000 title description 3
- 238000003756 stirring Methods 0.000 claims description 25
- 239000008367 deionised water Substances 0.000 claims description 21
- 229910021641 deionized water Inorganic materials 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
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- 235000003181 Panax pseudoginseng Nutrition 0.000 claims description 16
- 125000003118 aryl group Chemical group 0.000 claims description 15
- 239000003795 chemical substances by application Substances 0.000 claims description 15
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 claims description 14
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- 238000002156 mixing Methods 0.000 claims description 11
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- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 6
- NKWPZUCBCARRDP-UHFFFAOYSA-L calcium bicarbonate Chemical compound [Ca+2].OC([O-])=O.OC([O-])=O NKWPZUCBCARRDP-UHFFFAOYSA-L 0.000 description 6
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- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
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- 241000588724 Escherichia coli Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
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- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241001093501 Rutaceae Species 0.000 description 1
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- 241000607764 Shigella dysenteriae Species 0.000 description 1
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- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
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- ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical compound C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- 229940065181 bacillus anthracis Drugs 0.000 description 1
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- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 1
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 1
- 229940043256 calcium pyrophosphate Drugs 0.000 description 1
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- 201000002170 dentin sensitivity Diseases 0.000 description 1
- 238000013461 design Methods 0.000 description 1
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- 229910003460 diamond Inorganic materials 0.000 description 1
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- 235000019821 dicalcium diphosphate Nutrition 0.000 description 1
- 235000019700 dicalcium phosphate Nutrition 0.000 description 1
- 229940095079 dicalcium phosphate anhydrous Drugs 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 206010013023 diphtheria Diseases 0.000 description 1
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- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
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- 230000002427 irreversible effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
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- 239000008164 mustard oil Substances 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 150000004965 peroxy acids Chemical class 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 229940115939 shigella sonnei Drugs 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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- 230000036347 tooth sensitivity Effects 0.000 description 1
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- 201000008297 typhoid fever Diseases 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 229940118696 vibrio cholerae Drugs 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Birds (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of oral care, and relates to toothpaste containing green pricklyash peel extract and a preparation method thereof. According to the invention, the medical and edible green pricklyash peel extract is added into the toothpaste to replace the traditional chemical medicines, so that the effects of cleaning, resisting bacteria, whitening, relieving pain, diminishing inflammation and preventing moth can be achieved, and side effects caused by long-term use of the chemical medicines to consumers can be avoided.
Description
Technical Field
The invention relates to the technical field of oral care, in particular to toothpaste containing green pricklyash peel extract and a preparation method thereof.
Background
This section is intended to provide a background or context to the embodiments of the invention that are recited in the claims. The description herein is not admitted to be prior art by inclusion in this section.
The existing oral care products with the effects of relieving pain, diminishing inflammation and preventing moth are mainly added with chemical medicaments, fluoride and other components to play roles of relieving pain, diminishing inflammation and preventing moth, and irreversible side effects can be brought after long-term use. Thus, there is a need for an oral care product that eliminates the above side effects, replacing the traditional chemical-added efficacy toothpaste product.
The green pricklyash peel is shrub of Zanthoxylum of Rutaceae. The stem and branch of green pricklyash peel have no hair, and the basal part has lateral flat short thorns; odd feathered complex leaves, wide oval, needle-like or wide egg-like diamond; the canopy of the umbrella house-shaped umbrella is grown on top of the umbrella inflorescence, and is wide oval; the petals are light yellow and white, long round and few without flower columns; the fruit pieces are reddish brown and have light-colored narrow edges; the flowering period is 7-9 months; the fruit period is 9-12 months. The green pepper is named as green pepper because its green pod is dark green or brown green after maturation.
The green pricklyash peel has the effects of warming the middle-jiao and relieving pain, killing parasites and relieving itching, invigorating stomach, dispelling wind and cold, killing parasites and detoxifying, relieving itching and removing fishy smell, has obvious inhibition effects on 10 gram-positive bacteria such as bacillus anthracis, streptococcus hemolyticus, diphtheria bacillus, pneumococcus, staphylococcus aureus, lemon color and white staphylococcus, bacillus subtilis and the like, and intestinal pathogenic bacteria such as escherichia coli, shigella sonnei, bacillus dysenteriae, bacillus proteus, typhoid and paratyphoid bacillus, pseudomonas aeruginosa, vibrio cholerae and the like, and has high medicinal value.
Disclosure of Invention
The invention aims to provide toothpaste which not only can achieve good effects of relieving pain, diminishing inflammation and preventing moth, but also can avoid side effects brought to consumers due to long-term use, and is suitable for long-term use of oral health care products.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows.
In one aspect, the invention provides toothpaste containing green pricklyash peel extract, which comprises the following components: deionized water, an auxiliary agent and 1% -10% of green pricklyash peel extract.
According to the invention, the Chinese prickly ash fruit extract used as both medicine and food is added to replace the traditional chemical medicine, so that various side effects on the teeth of a human body caused by long-term use of the chemical medicine are avoided.
In some embodiments, the adjuvants include pseudo-ginseng extract, moisturizers, abrasives, preservatives, fragrances, thickeners, and sugar flavors.
In some embodiments, the toothpaste comprises by weight: 1-10 parts of green pepper extract, 1-10 parts of pseudo-ginseng extract, 30-60 parts of humectant, 20-50 parts of friction agent, 0.1-0.5 part of preservative, 0.5-1.5 parts of aromatic, 0.5-2 parts of thickener, 0.1-5 parts of sugar taste agent and 15-50 parts of deionized water.
In another aspect, the present invention also provides a method for preparing toothpaste containing green pricklyash peel extract, comprising the following steps: grinding 20-50 parts by weight of friction agent into powder with fineness of 5-10 mu m, adding 30-60 parts of humectant, adding 10 parts of deionized water, stirring and mixing uniformly, continuing stirring to ensure uniform mixing, adding 1-10 parts of green pricklyash peel extract and 1-10 parts of pseudo-ginseng extract, continuously stirring uniformly to ensure uniform and fine texture of toothpaste, adding 0.1-0.5 part of preservative and 0.5-1.5 parts of aromatic, stirring uniformly again, adding 0.5-2 parts of thickener and 0.1-5 parts of sugar taste agent, and continuing stirring until the ideal texture and taste are achieved. Finally, adding the rest deionized water gradually, stirring until the consistency of the toothpaste reaches 9-30 mm, and filling the prepared toothpaste into a clean toothpaste tube or container.
In some embodiments, the weight ratio of each component in the method steps is as follows: 1-10 parts of green pepper extract, 1-10 parts of pseudo-ginseng extract, 30-60 parts of humectant, 20-50 parts of friction agent, 0.1-0.5 part of preservative, 0.5-1.5 parts of aromatic, 0.5-2 parts of thickener, 0.1-5 parts of sugar taste agent and 15-50 parts of deionized water.
Compared with the prior art, the invention has the following beneficial effects:
according to the invention, the medical and edible green pricklyash peel extract is added into the toothpaste to replace the traditional chemical medicines, so that the effects of cleaning, resisting bacteria, whitening, relieving pain, diminishing inflammation and preventing moth can be achieved, and side effects caused by long-term use of the chemical medicines to consumers can be avoided.
The exemplary embodiments of the present invention and the descriptions thereof are for explaining the present invention and do not constitute an undue limitation of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the following examples, for the purpose of making the objects, technical solutions and advantages of the present invention more apparent, and the description thereof is merely illustrative of the present invention and not intended to be limiting. It should be noted that the present invention is already in a practical development and use stage.
In the description of the present invention, it should be understood that the terms "upper," "lower," "front," "rear," "left," "right," and the like indicate orientations or positional relationships, and are merely used for convenience in describing the invention, and are not meant to indicate or imply that the devices or elements referred to must have a particular orientation, be configured and operated in a particular orientation, and are not to be construed as limiting the invention. In addition, the terms "first," "second," etc. of the present invention are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance.
Throughout the specification and claims, unless explicitly stated otherwise, the term "comprise" or variations thereof such as "comprises" or "comprising", etc. will be understood to include the stated element or component without excluding other elements or components.
The toothpaste of the invention replaces the traditional chemical medicines by adding the green pricklyash peel extract with both medicine and food, thereby avoiding various side effects caused by long-term use of the chemical medicines on human teeth. Therefore, the green pricklyash peel extract is extracted from the green pricklyash peel before preparing the toothpaste, and the green pricklyash peel extract is extracted by the following steps:
(1) preparing green pricklyash peel: fresh green pricklyash peel with good quality is selected. The whole green pricklyash peel fruits can be selected to be cleaned and dried;
(2) grinding green pricklyash peel: grinding pericarpium Zanthoxyli fruit into fine powder, and optionally grinding with a grinder, mortar or food processor;
(3) extracting the zanthoxylic acid: adding pericarpium Zanthoxyli powder into a soaking container, and adding appropriate amount of edible wine or high alcohol. After stirring evenly, covering the cover, and standing for a plurality of hours or overnight so that the zanthoxylic acid is dissolved in the solvent;
(4) filtering the liquid: filtering the solution using a filter paper or a filter funnel to remove solid residues and impurities;
(5) evaporating the solvent: pouring the filtered solution into a shallow tray or a glass vessel, placing the solution in a well ventilated place, and allowing the solvent to volatilize slowly;
(6) collecting the Zanthoxylum acid: when the solvent is completely volatilized, crystals of Zanthoxylum acid remain. The crystals are carefully scraped together by a scraper or a sharp object, and the zanthoxylic acid can be obtained.
The extract mainly contains one important extract of green pricklyash peel
The green pricklyash peel has the effects of resisting bacteria and viruses, mainly has the effect of inhibiting the growth of bacteria, particularly has a good inhibiting effect on drug-resistant bacteria, can inhibit the replication of certain viruses, and has a certain prevention and treatment effect on virus infections such as gastrointestinal viruses.
The method can be used for extracting the zanthoxylic acid from green Chinese prickly ash. Note that the extraction of bunge pricklyash acid requires some laboratory skills and equipment, while also performing safe handling to avoid contact with sensitive areas of the eye, mouth, etc.
After the green pricklyash peel extract is obtained, green pricklyash peel toothpaste is prepared according to different formulation ratios, and the different formulation ratios and toothpaste performance differences thereof are shown by way of example.
Example 1
The embodiment provides toothpaste containing green pricklyash peel extract, which comprises the following components: deionized water, an auxiliary agent and 1% -10% of green pricklyash peel extract.
Optionally, the auxiliary agent comprises pseudo-ginseng extract, humectant, abrasive, preservative, aromatic, thickener and sugar flavoring agent. Wherein the humectant can prevent toothpaste from solidifying and hardening in the soft tube, has luster and other effects, and can be glycerol, propylene glycol, sorbitol, etc. Abrasives are a commonly used component of toothpastes that aid in cleaning teeth and polishing dental surfaces, removing pigmentation and plaque, and may be selected from calcium carbonate, dibasic calcium phosphate, tribasic calcium pyrophosphate, silicon dioxide, aluminum hydroxide, silicates, and the like. The sugar taste agent is mainly used for increasing the taste of the toothpaste and improving the taste of the toothpaste, and can be selected from sucrose, sorbitol and the like, which can enable the toothpaste to have certain sweet taste and be more pleasant to use. The preservative is a chemical in the toothpaste that protects the toothpaste from bacterial contamination, extends shelf life, and allows for compatibility of other ingredients. Common preservatives are sodium benzoate, parahydroxybenzoate and the like. Of course, in addition to the above-mentioned auxiliary agents, the auxiliary agents in the toothpaste of the present embodiment may further include pigments, surfactants, binders, and the like.
Optionally, the toothpaste comprises the following components in parts by weight: 1-10 parts of green pepper extract, 1-10 parts of pseudo-ginseng extract, 30-60 parts of humectant, 20-50 parts of friction agent, 0.1-0.5 part of preservative, 0.5-1.5 parts of aromatic, 0.5-2 parts of thickener, 0.1-5 parts of sugar taste agent and 15-50 parts of deionized water.
Preferably, the embodiment adopts the following components in proportion: 1 part of green pricklyash peel extract, 6 parts of pseudo-ginseng extract, 35 parts of glycerin, 30 parts of calcium bicarbonate, 0.5 part of parahydroxybenzoate, 1.5 parts of aromatic, 2 parts of sodium carboxymethyl cellulose, 3 parts of sorbitol and 21 parts of deionized water.
In addition, the embodiment also provides a preparation method of the toothpaste by the method, which comprises the following steps:
in a clean container, 30 parts by weight of calcium bicarbonate is ground into powder with fineness of 5-10 mu m, 35 parts of glycerol and 10 parts of deionized water are added, stirring and mixing are uniform, stirring is continued, mixing is ensured to be uniform, 1 part of green pricklyash peel extract and 6 parts of pseudo-ginseng extract are added, and stirring is continued to be uniform, so that uniform and fine texture of toothpaste is ensured. 0.5 part of parahydroxybenzoate and 1.5 parts of aromatic were added and stirred again uniformly to ensure stability and odor of the product. 2 parts of sodium carboxymethylcellulose and 3 parts of sorbitol are added and stirring is continued until the desired texture and taste are achieved. Finally, the rest deionized water is gradually added, and the mixture is continuously stirred until the toothpaste reaches the required consistency (9 mm-30 mm) and fluidity. Filling the prepared toothpaste into a clean toothpaste tube or container.
The consistency of the toothpaste is defined herein as the toothpaste is easily extruded from the hose and is in the form of strips. The foam amount is specified because the foaming agent in the toothpaste is the main cause of generating foam, and the foaming agent plays roles of emulsifying essence and stabilizing paste in the toothpaste. When the toothpaste is used for brushing teeth, foam is generated to achieve the effect of decontamination.
Example 2
A toothpaste containing green pricklyash peel extract, comprising by weight: 10 parts of green pricklyash peel extract, 6 parts of pseudo-ginseng extract, 30 parts of glycerin, 28 parts of calcium bicarbonate, 0.5 part of parahydroxybenzoate, 1.5 parts of aromatic, 2 parts of sodium carboxymethyl cellulose, 2 parts of sorbitol and 20 parts of deionized water.
The preparation method of the toothpaste of the embodiment comprises the following steps:
in a clean container, 28 parts by weight of calcium bicarbonate are ground into powder with fineness of 5-10 mu m, 30 parts of glycerol and 10 parts of deionized water are added, stirring and mixing are uniform, stirring is continued, mixing is ensured to be uniform, 10 parts of green pricklyash peel extract and 6 parts of pseudo-ginseng extract are added, and stirring is continued to be uniform, so that uniform and fine texture of toothpaste is ensured. 0.5 part of parahydroxybenzoate and 1.5 parts of aromatic were added and stirred again uniformly to ensure stability and odor of the product. 2 parts of sodium carboxymethylcellulose and 2 parts of sorbitol are added and stirring is continued until the desired texture and taste are achieved. Finally, the rest deionized water is gradually added, and the mixture is continuously stirred until the toothpaste reaches the required consistency (9 mm-30 mm) and fluidity. Filling the prepared toothpaste into a clean toothpaste tube or container.
Example 3
A toothpaste containing green pricklyash peel extract, comprising by weight: 5 parts of green pricklyash peel extract, 6 parts of pseudo-ginseng extract, 30 parts of glycerin, 33 parts of calcium bicarbonate, 0.5 part of parahydroxybenzoate, 1.5 parts of aromatic, 2 parts of sodium carboxymethyl cellulose, 2 parts of sorbitol and 20 parts of deionized water.
The preparation method of the toothpaste of the embodiment comprises the following steps:
in a clean container, 33 parts by weight of calcium bicarbonate are ground into powder with the fineness of 5-10 mu m, 30 parts of glycerol and 10 parts of deionized water are added, stirring and mixing are uniform, stirring is continued, mixing is ensured to be uniform, 5 parts of green pricklyash peel extract and 6 parts of pseudo-ginseng extract are added, and stirring is continued to be uniform, so that uniform and fine texture of toothpaste is ensured. 0.5 part of parahydroxybenzoate and 1.5 parts of aromatic were added and stirred again uniformly to ensure stability and odor of the product. 2 parts of sodium carboxymethylcellulose and 2 parts of sorbitol are added and stirring is continued until the desired texture and taste are achieved. Finally, the rest deionized water is gradually added, and the mixture is continuously stirred until the toothpaste reaches the required consistency (9 mm-30 mm) and fluidity. Filling the prepared toothpaste into a clean toothpaste tube or container.
Comparison experiment:
the toothpastes of examples 1 to 3 were subjected to experimental performance comparison, respectively, and 2 types of conventional toothpastes without green pricklyash peel extract were selected as blank experiments, and the design of the comparison experiments is as follows:
(1) PH experiment: the pH paper or pH meter is used to measure the pH of the above examples, as well as conventional toothpastes, which should generally be acidic or neutral, and peracids or overbases may have adverse effects on oral health.
(2) Cleanability test: the above examples were compared with conventional toothpastes using artificial tooth models or eggshells, and the like, and colored by soaking with strong tea or coffee. Equal amounts of toothpastes of different samples were prepared, and the toothpastes were used to make a loop of each brush 20 turns in a certain area, and the effect of the toothpastes on removal of dental plaque and stain was evaluated by observing whether the model would be worn by the toothpastes.
(3) Antibacterial experiment: the antibacterial effect of the toothpaste can be evaluated by contacting the conventional toothpaste and the conventional oral bacteria, taking saliva of different human oral cavities, culturing the saliva for a period of time by bacteria, taking equal amounts of each sample of toothpaste, diluting the toothpaste, mixing the diluted toothpaste with the saliva, and comparing colony formation conditions, wherein the antibacterial effect of the toothpaste can be evaluated by using a bacterial culture medium and an agar plate.
(4) Oral mildness test: the above examples and the degree of stimulation of the oral mucosa by conventional toothpastes were tested using chemical methods or specialized equipment. This may include testing of human cells for effects on mustard oil or other components that may cause irritation.
(5) Tooth whitening effect experiment: the whitening effect of the toothpaste is evaluated by testing on artificial enamel or eggshells with colored solutions or dyes, and the effects of the above-mentioned examples and the conventional toothpaste can be compared by distinguishing the brightness or the image brightness of each sample through an image recognition technology by means of a computer.
The results of the specific experimental data are shown in table 1.
Table 1 comparative experimental data
Therefore, the cleaning performance, the mildness and the whitening effect of the toothpaste added with the green pepper extract are equivalent to those of the traditional toothpaste, and the toothpaste is remarkable in that the PH value of a sample added with 1 part of green pepper extract in the embodiment 1 is 9.68, and the sample is alkaline, so that the acid environment in the oral cavity can be neutralized, the problem of tooth sensitivity is reduced, and the toothpaste is suitable for people with more sensitive teeth; the green pricklyash peel extract added in example 2 was 10 parts, and the pH of the sample was 7.78, neutral, and suitable for most people. The green pricklyash peel extract added in example 3 was relatively centered and 5 parts, and the PH of the sample was 9.24, and was alkaline, and it can be seen that the more the green pricklyash peel extract was added, the more acidic the toothpaste, the better the PH of the toothpaste was generally neutral, and the PH of most of the toothpastes on the market was about 8.5-9, depending on various national standards related to toothpastes and the degree of tolerance of the human body.
In addition, according to the antibacterial experiment, a little residual bacteria is found in the sample experiment of adding 1 part of green pricklyash peel extract in example 1, 5 parts of green pricklyash peel extract in example 3 and 10 parts of green pricklyash peel extract in example 2, no residual bacteria are found in the sample experiment, and a certain common traditional toothpaste can occasionally find residual bacteria, which means that the more the green pricklyash peel extract is added, the better the antibacterial effect of the sample is, and it is seen that the addition of the green pricklyash peel extract can enable the toothpaste to have the antibacterial effect equivalent to that of the traditional toothpaste, even better than that of some traditional common toothpastes.
In conclusion, the toothpaste containing the green pepper extract can achieve the cleaning performance, mildness and whitening effect equivalent to those of the traditional toothpaste, and the antibacterial effect is equivalent to or even better than that of the traditional toothpaste, so that the toothpaste containing the green pepper extract can replace the traditional toothpaste containing chemical medicines, and achieves good cleaning, antibacterial and whitening effects. In addition, due to the characteristics of the green pepper, the toothpaste also has the effects of relieving pain, diminishing inflammation and preventing moth.
In the foregoing embodiments of the present application, the descriptions of the embodiments are emphasized, and for a portion of this disclosure that is not described in detail in this embodiment, reference is made to the related descriptions of other embodiments.
It should be noted that, for simplicity of description, the foregoing embodiments are all illustrated as a series of acts, but it should be understood by those skilled in the art that the present application is not limited by the order of acts described, as some steps may be performed in other orders or concurrently in accordance with the application. Further, those skilled in the art will also appreciate that the embodiments described in the specification are all preferred embodiments, and that the acts and modules referred to are not necessarily required in the present application.
The foregoing detailed description of the invention has been presented for purposes of illustration and description, and it should be understood that the foregoing is by way of illustration and example only, and is not intended to limit the scope of the invention.
Claims (7)
1. A toothpaste containing green pricklyash peel extract, which is characterized by comprising the following components: deionized water, an auxiliary agent and 1% -10% of green pricklyash peel extract.
2. The toothpaste containing green pricklyash peel extract according to claim 1, wherein the auxiliary agent comprises pseudo-ginseng extract, humectant, abrasive, preservative, aromatic, thickener and sugar flavoring agent.
3. A toothpaste comprising a green pricklyash peel extract according to claim 2, wherein the toothpaste comprises by weight: 1-10 parts of green pepper extract, 1-10 parts of pseudo-ginseng extract, 30-60 parts of humectant, 20-50 parts of friction agent, 0.1-0.5 part of preservative, 0.5-1.5 parts of aromatic, 0.5-2 parts of thickener, 0.1-5 parts of sugar taste agent and 15-50 parts of deionized water.
4. A preparation method of toothpaste containing green pricklyash peel extract is characterized by comprising the following steps: grinding 20-50 parts by weight of friction agent into powder with fineness of 5-10 mu m, adding 30-60 parts of humectant, adding 10 parts of deionized water, stirring and mixing uniformly, continuing stirring to ensure uniform mixing, adding 1-10 parts of green pricklyash peel extract and 1-10 parts of pseudo-ginseng extract, continuously stirring uniformly to ensure uniform and fine texture of toothpaste, adding 0.1-0.5 part of preservative and 0.5-1.5 parts of aromatic, stirring uniformly again, adding 0.5-2 parts of thickener and 0.1-5 parts of sugar taste agent, continuing stirring until the ideal texture and taste are achieved, finally gradually adding the rest deionized water, continuously stirring until the consistency of the toothpaste reaches 9-30 mm, and filling the prepared toothpaste into a clean toothpaste tube or container.
5. The method for preparing the toothpaste containing the green pepper extract as claimed in claim 4, wherein the weight ratio of the components is as follows: 1-10 parts of green pepper extract, 1-10 parts of pseudo-ginseng extract, 30-60 parts of humectant, 20-50 parts of friction agent, 0.1-0.5 part of preservative, 0.5-1.5 parts of aromatic, 0.5-2 parts of thickener, 0.1-5 parts of sugar taste agent and 15-50 parts of deionized water.
6. The method for preparing toothpaste containing green pricklyash peel extract according to claim 5, wherein the pH of the toothpaste is 5.5-10.
7. The method for preparing the toothpaste containing the green pepper extract as claimed in claim 6, wherein the foam amount of the toothpaste is 90mm-150mm.
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