CN117123287A - High flux drop generator - Google Patents
High flux drop generator Download PDFInfo
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- CN117123287A CN117123287A CN202311157157.0A CN202311157157A CN117123287A CN 117123287 A CN117123287 A CN 117123287A CN 202311157157 A CN202311157157 A CN 202311157157A CN 117123287 A CN117123287 A CN 117123287A
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- sample
- tube
- teflon
- inlet end
- high throughput
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- 230000004907 flux Effects 0.000 title abstract description 7
- 229920001296 polysiloxane Polymers 0.000 claims abstract description 69
- 239000004809 Teflon Substances 0.000 claims abstract description 65
- 229920006362 Teflon® Polymers 0.000 claims abstract description 65
- 239000007788 liquid Substances 0.000 claims abstract description 43
- 238000002347 injection Methods 0.000 claims abstract description 22
- 239000007924 injection Substances 0.000 claims abstract description 22
- 239000012530 fluid Substances 0.000 claims abstract description 21
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000000741 silica gel Substances 0.000 claims abstract description 10
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims abstract description 5
- 239000003292 glue Substances 0.000 claims description 4
- 238000001514 detection method Methods 0.000 abstract description 12
- 238000010008 shearing Methods 0.000 abstract description 11
- 239000000523 sample Substances 0.000 description 82
- 239000012071 phase Substances 0.000 description 8
- 238000010586 diagram Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 239000008346 aqueous phase Substances 0.000 description 3
- 239000003086 colorant Substances 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012408 PCR amplification Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a high-flux liquid drop generator, which comprises a multi-pass receiving pipe and a multi-pass conveying pipe, wherein the multi-pass receiving pipe comprises a first inlet end, a first outlet end and at least two liquid drop generating ends, the multi-pass conveying pipe comprises a second inlet end, a second outlet end and at least two conveying ends, the liquid drop generating ends and the conveying ends are connected through a sample silicone tube, a sample liquid and a teflon capillary tube are arranged in the sample silicone tube, the teflon capillary tube and the silica gel tube are arranged in a sealing way, the number of the liquid drop generating ends, the conveying ends and the sample silicone tube is adjusted according to the requirement, the high flux can be realized with low cost, the follow-up detection is facilitated, and the detection efficiency and the detection performance are improved; the second inlet end is connected with an injection part, the injection part is used for providing fluid shearing force, micro liquid drops of a sample can be formed through one injection part, the stability of liquid drop generation can be ensured, the structure is simple, the sample consumption is less, and the cost is low.
Description
Technical Field
The invention relates to the technical field of droplet generators, in particular to a high-flux droplet generator.
Background
In portable biological applications, reproducible, rapid experiments require accurate droplet generation techniques to ensure the reliability of the analysis results. From the accuracy of control of fluid pressure to precision manufactured tubular structures. Most droplet generators currently on the market are complex in construction, costly, or difficult to control the ratio between shear and capillary forces in portable biological applications. The frequency and size of the droplets is typically dependent on the flow rate ratio at the chip inlet, which makes it highly dependent on the precisely controlled pressure of the controller to achieve stable droplets. In the traditional continuous flow micro-fluidic system, due to the characteristic of low-Reynolds-number laminar flow, the mixing of continuous fluid is difficult, and the consumption of samples is increased. In addition, when the number of parallel tests needs to be increased to increase the throughput of reactions or assays, the complexity and operational difficulty of chip preparation tends to increase. For subsequent PCR amplification and quantitative analysis and research, only a single sample solution can be detected at a time, and the traditional method has low efficiency and high cost.
Disclosure of Invention
The present invention aims to solve at least one of the technical problems existing in the prior art. Therefore, the invention provides the high-flux liquid drop generator which can realize high flux at low cost and improve the detection efficiency and the detection performance.
According to a first aspect of the present invention, a high throughput droplet generator comprises
The multi-way receiving tube comprises a first inlet end, a first outlet end and at least two droplet generation ends, wherein the first inlet end and the first outlet end are arranged opposite to each other, and the droplet generation ends are arranged between the first inlet end and the first outlet end;
the multi-way conveying pipe comprises a second inlet end, a second outlet end and at least two conveying ends, wherein the second inlet end and the second outlet end are oppositely arranged, the second outlet end is connected with the first inlet end, and the second inlet end is connected with an injection part to provide fluid shear force;
the liquid drop generation end is connected with the conveying end through a sample silica gel tube, a sample liquid and a teflon capillary tube are arranged in the sample silica gel tube, and the teflon capillary tube and the silica gel tube are arranged in a sealing mode.
A high throughput droplet generator according to embodiments of the first aspect of the invention has at least the following beneficial effects: the high-flux liquid drop generator comprises a multi-pass receiving pipe and a multi-pass conveying pipe, wherein the multi-pass receiving pipe comprises a first inlet end, a first outlet end and at least two liquid drop generating ends, the multi-pass conveying pipe comprises a second inlet end, a second outlet end and at least two conveying ends, the liquid drop generating ends and the conveying ends are connected through a sample silicone tube, a sample liquid and a teflon capillary tube are arranged in the sample silicone tube, the teflon capillary tube and the silicone tube are arranged in a sealing manner, the number of the liquid drop generating ends, the conveying ends and the sample silicone tube is adjusted according to the requirement, the high flux can be realized at low cost, the follow-up detection is facilitated, and the detection efficiency and the detection performance are improved; the second inlet end is connected with an injection part, the injection part is used for providing fluid shearing force, micro liquid drops of a sample can be formed through one injection part, the stability of liquid drop generation can be ensured, the structure is simple, the sample consumption is less, and the cost is low.
According to some embodiments of the invention, the droplet generating end is provided with a plurality, the droplet generating end is connected with a plurality of sample silicone tubes, and the sample silicone tubes are provided with a plurality of different sample liquids.
According to some embodiments of the invention, a plurality of sample fluids are disposed within each of the sample silicone tubes.
According to some embodiments of the invention, the droplet generating end is provided with a plurality of sample silicone tubes, and the sample silicone tubes are provided with the teflon capillaries with different inner diameters.
According to some embodiments of the invention, the teflon capillary is provided with a plurality of capillaries, and the plurality of teflon capillaries are uniformly distributed in the sample silicone tube.
According to some embodiments of the invention, the injection member is provided as an injection pump.
According to some embodiments of the invention, the teflon capillary tube is sealed with the silicone tube by glue.
According to some embodiments of the invention, the teflon capillary tube is disposed against the tube wall of the sample silicone tube.
According to some embodiments of the invention, the teflon capillary tube is disposed coaxially with the sample silicone tube.
According to some embodiments of the invention, the teflon capillary tube is disposed eccentrically within the sample silicone tube.
Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
Drawings
The foregoing and/or additional aspects and advantages of the invention will become apparent and may be better understood from the following description of embodiments taken in conjunction with the accompanying drawings in which:
FIG. 1 is a schematic diagram of a high throughput droplet generator according to an embodiment of the invention;
FIG. 2 is a schematic illustration of a high throughput droplet generator of an embodiment of the invention provided with a plurality of teflon capillaries;
FIG. 3 is a schematic illustration of the configuration of the high throughput droplet generator of FIG. 1 with different sample fluids disposed on different sample silicone tubes;
FIG. 4 is a schematic diagram of a high throughput droplet generator according to an embodiment of the present invention in which the same sample silicone tube is provided with different sample liquids;
FIG. 5 is a schematic illustration of the configuration of a high throughput droplet generator of an embodiment of the invention in which different sample silicone tubes are provided with a plurality of different sample fluids;
FIG. 6 is a schematic diagram of a high throughput droplet generator of an embodiment of the invention in which different sample silicone tubes are provided with teflon capillaries of different tube diameters;
fig. 7 is a schematic structural diagram of a high-throughput droplet generator according to an embodiment of the present invention, in which a plurality of teflon capillaries with the same diameter are disposed on the same silica gel tube.
Detailed Description
Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the invention.
In the description of the present invention, it should be understood that references to orientation descriptions such as upper, lower, front, rear, left, right, inner, outer, etc. are based on the orientation or positional relationship shown in the drawings, are merely for convenience of describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention.
In the description of the present invention, a number means one or more, a number means two or more, and greater than, less than, exceeding, etc. are understood to not include the present number, and above, below, within, etc. are understood to include the present number. The description of the first and second is for the purpose of distinguishing between technical features only and should not be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.
In the description of the present invention, unless explicitly defined otherwise, terms such as arrangement, mounting, connection, assembly, cooperation, etc. should be construed broadly and the specific meaning of the terms in the present invention can be reasonably determined by a person skilled in the art in combination with the specific contents of the technical solution.
A high throughput droplet generator according to an embodiment of the invention is described below with reference to fig. 1 to 7.
1-7, the high-throughput droplet generator of the embodiment of the invention comprises a multi-pass receiving tube 100 and a multi-pass conveying tube 200, wherein the multi-pass receiving tube 100 comprises a first inlet end 110, a first outlet end 120 and at least two droplet 400 generating ends 130, the multi-pass conveying tube 200 comprises a second inlet end 210, a second outlet end 220 and at least two conveying ends 230, the droplet 400 generating ends 130 and the conveying ends 230 are connected through a sample silicone tube 300, a sample liquid 310 and a teflon capillary 320 are arranged in the sample silicone tube 300, the teflon capillary 320 and the silicone tube are arranged in a sealing way, the sample liquid 310 is subjected to the shearing force of fluid at the outlet after passing through the teflon capillary 320, and the droplet 400 can be formed. The number of the droplet 400 generating end 130, the conveying end 230 and the sample silicone tube 300 is adjusted according to the requirement, so that high flux can be realized at low cost, follow-up detection is facilitated, and detection efficiency and detection performance are improved. The use of the sample silicone tube 300 as the tubing material for the droplet 400 not only reduces fluid residue waste, avoids cross contamination with the external environment, but also improves throughput. The second inlet end 210 is connected with an injection component, the first inlet end 110 is opposite to the first outlet end 120, the second inlet end 210 is opposite to the second outlet end 220, the second outlet end 220 is connected with the first inlet end 110, the liquid drop 400 generating end 130 is arranged between the first inlet end 110 and the first outlet end 120, the injection component is used for providing fluid shearing force, the liquid drop 400 generating end 130 is arranged between the first inlet end 110 and the first outlet end 120, the shearing force can be provided for a plurality of liquid drop 400 generating ends 130 through one injection component, the structure is simple, and high flux can be realized with low cost.
According to some embodiments of the present invention, the plurality of droplet 400 generating ends 130 are provided, and the plurality of droplet 400 generating ends 130 are connected with the plurality of sample silicone tubes 300, and the plurality of sample silicone tubes 300 are provided with the plurality of different sample liquids 310. The generating ends 130 of the liquid drops 400 are provided with a plurality of, the generating ends 130 of the liquid drops 400 are correspondingly connected with a plurality of sample silica gel tubes 300, and a plurality of different sample liquids 310 are arranged in different sample silica gel tubes 300, so that different samples can be distinguished according to fluorescent colors, and the function of detecting a plurality of samples at one time is achieved.
According to some embodiments of the present invention, a plurality of sample fluids 310 are disposed within each sample silicone tube 300. A plurality of sample liquids 310 are arranged in one sample silicone tube 300, different sample liquids 310 are separated by oil phase, different sample liquids 310 can form liquid drops 400 successively, different sample liquids 310 use different fluorescent dyes, different samples can be distinguished according to fluorescent colors, and the function of detecting a plurality of samples at one time is achieved. It can be appreciated that in some embodiments, two or more sample liquids 310 may be disposed in each sample silicone tube 300, and a plurality of sample silicone tubes 300 are disposed, so that the sample liquids 310 are different from each other, and multiple samples can be detected at a time, thereby improving the sample detection efficiency.
According to some embodiments of the present invention, the droplet 400 generating end 130 is provided in plurality, the plurality of droplet 400 generating ends 130 are connected with the plurality of sample silicone tubes 300, and the plurality of sample silicone tubes 300 are provided with teflon capillaries 320 having different inner diameters. The teflon capillary 320 is arranged in the sample silicone tube 300, the sample silicone tube 300 is provided with a plurality of teflon capillaries, the inner diameters of the teflon capillaries 320 of the plurality of sample silicone tubes 300 are different, liquid drops 400 with different sizes can be generated, different sample liquids 310 are distinguished according to different volumes of the liquid drops 400, and the function of detecting various samples at one time is achieved.
According to some embodiments of the present invention, the teflon capillary tube 320 is provided with a plurality of teflon capillary tubes 320, and the plurality of teflon capillary tubes 320 are uniformly distributed in the sample silicone tube 300. The teflon capillary 320 is provided with a plurality of teflon capillaries, and the plurality of teflon capillaries 320 are provided in the sample silicone tube 300 to communicate the multi-pass receiving tube 100 with the sample silicone tube 300 and to convey the sample liquid 310 into the multi-pass receiving tube 100. Specifically, the teflon capillaries 320 are uniformly distributed in the sample silicone tube 300, so that the space between the sample silicone tube 300 and the multi-way receiving tube 100 can be fully utilized, and the efficiency of generating the liquid drops 400 is improved. It will be appreciated that in some embodiments, the plurality of teflon capillaries 320 disposed within different sample silicone tubes 300 can be configured to have different inner diameters according to the difference of the sample fluid 310, so as to achieve the function of detecting multiple samples at a time while improving the efficiency of generating the droplet 400 and improving the throughput, and simultaneously resolving different sample fluids 310 according to different volumes of the droplet 400.
According to some embodiments of the invention, the injection member is provided as an injection pump. The second inlet end 210 is connected with an injection component, the first inlet end 110 is opposite to the first outlet end 120, the second inlet end 210 is opposite to the second outlet end 220, the second outlet end 220 is connected with the first inlet end 110, the droplet 400 generating end 130 is arranged between the first inlet end 110 and the first outlet end 120, the injection component is arranged as an injection pump, the injection pump provides fluid shearing force for the droplet generator, the droplet 400 generating end 130 is arranged between the first inlet end 110 and the first outlet end 120, and a power source can provide shearing force for the plurality of droplet 400 generating ends 130 through the injection pump.
According to some embodiments of the present invention, the teflon capillary tube 320 is sealed with the sample silicone tube 300 by glue. A gap is arranged between the teflon capillary 320 and the sample silicone tube 300, glue is arranged in the gap between the teflon capillary 320 and the sample silicone tube 300, and can seal between the teflon capillary 320 and the sample silicone tube 300, so that water phase can only flow out through the teflon capillary 320, and finally liquid drops 400 are formed under the action of shearing force.
According to some embodiments of the invention, teflon capillary 320 is disposed against the wall of sample silicone tubing 300. The teflon capillary 320 is disposed in the sample silicone tube 300, specifically, the teflon capillary 320 is disposed close to the tube wall of the sample silicone tube 300, and the teflon capillary 320 and the sample silicone tube 300 are sealed, so that the water phase can only flow out through the teflon capillary 320. The aqueous phase flows into the multi-way receiving tube 100 through the teflon capillary 320 closely attached to the wall of the sample silicone tube 300, forms droplets 400 by the shearing force of the oil phase fluid at the outlet of the teflon capillary 320, and finally flows out from the first outlet end 120 of the multi-way receiving tube 100.
According to some embodiments of the invention, teflon capillary 320 is disposed coaxially with sample silicone tube 300. The teflon capillary 320 is disposed in the sample silicone tube 300, specifically, the teflon capillary 320 is disposed coaxially with the sample silicone tube 300, and the teflon capillary 320 is sealed with the sample silicone tube 300, so that the water phase can only flow out through the teflon capillary 320. The aqueous phase flows into the multi-pass receiving tube 100 through the coaxially arranged teflon capillary 320, is subjected to the shearing force of the oil phase fluid at the outlet of the teflon capillary 320 to form droplets 400, and finally flows out from the first outlet end 120 of the multi-pass receiving tube 100.
According to some embodiments of the invention, teflon capillary 320 is disposed eccentrically within sample silicone tube 300. Specifically, the teflon capillary 320 is disposed offset from the center of the sample silicone tube 300, and the teflon capillary 320 is sealed with the sample silicone tube 300, so that the water phase can only flow out through the teflon capillary 320. The aqueous phase flows into the multi-pass receiving tube 100 through the eccentric teflon capillary 320, is subjected to the shearing force of the oil phase fluid at the outlet of the teflon capillary 320 to form droplets 400, and finally flows out from the first outlet end 120 of the multi-pass receiving tube 100.
The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made within the knowledge of one of ordinary skill in the art without departing from the spirit of the present invention.
Claims (10)
1. A high throughput droplet generator, comprising:
the multi-way receiving tube comprises a first inlet end, a first outlet end and at least two droplet generation ends, wherein the first inlet end and the first outlet end are arranged opposite to each other, and the droplet generation ends are arranged between the first inlet end and the first outlet end;
the multi-way conveying pipe comprises a second inlet end, a second outlet end and at least two conveying ends, wherein the second inlet end and the second outlet end are oppositely arranged, the second outlet end is connected with the first inlet end, and the second inlet end is connected with an injection part to provide fluid shear force;
the liquid drop generation end is connected with the conveying end through a sample silica gel tube, a sample liquid and a teflon capillary tube are arranged in the sample silica gel tube, and the teflon capillary tube and the silica gel tube are arranged in a sealing mode.
2. The high throughput fluidic droplet generator of claim 1, wherein a plurality of said fluidic droplet generating ends are provided, a plurality of said fluidic droplet generating ends are connected with a plurality of sample silicone tubes, and a plurality of said sample silicone tubes are provided with a plurality of different said sample fluids.
3. A high throughput droplet generator according to any of claims 1 or 2, wherein a plurality of sample fluids are provided within each sample silicone tube.
4. The high throughput fluidic droplet generator of claim 1, wherein a plurality of said fluidic droplet generating ends are provided, a plurality of said fluidic droplet generating ends are connected with a plurality of sample silicone tubes, a plurality of said sample silicone tubes are provided with said teflon capillaries of different inner diameters.
5. The high throughput droplet generator of any one of claims 1 or 4, wherein a plurality of teflon capillaries are provided, and a plurality of teflon capillaries are uniformly distributed in said sample silicone tube.
6. A high throughput droplet generator according to claim 1, wherein said injection means is provided as an injection pump.
7. The high-throughput droplet generator of claim 1, wherein said teflon capillary tube is sealed to said silicone tube by glue.
8. A high throughput droplet generator according to claim 1, wherein said teflon capillary tube is disposed against the wall of said sample silicone tube.
9. A high throughput droplet generator according to claim 1, wherein said teflon capillary tube is arranged coaxially with said sample silicone tube.
10. A high throughput droplet generator according to claim 1, wherein said teflon capillary tube is disposed eccentrically within said sample silicone tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311157157.0A CN117123287A (en) | 2023-09-07 | 2023-09-07 | High flux drop generator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311157157.0A CN117123287A (en) | 2023-09-07 | 2023-09-07 | High flux drop generator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117123287A true CN117123287A (en) | 2023-11-28 |
Family
ID=88859850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311157157.0A Pending CN117123287A (en) | 2023-09-07 | 2023-09-07 | High flux drop generator |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117123287A (en) |
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2023
- 2023-09-07 CN CN202311157157.0A patent/CN117123287A/en active Pending
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