CN205691537U - A kind of for solution driving and the micro-fluidic chip mixed - Google Patents
A kind of for solution driving and the micro-fluidic chip mixed Download PDFInfo
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- CN205691537U CN205691537U CN201620562239.2U CN201620562239U CN205691537U CN 205691537 U CN205691537 U CN 205691537U CN 201620562239 U CN201620562239 U CN 201620562239U CN 205691537 U CN205691537 U CN 205691537U
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Abstract
The utility model discloses a kind of for solution driving and the micro-fluidic chip mixed, including glass negative and the PDMS cover plate being fixed on glass negative, described PDMS cover plate is provided with three folding zigzag microchannels；Evoked electrode all it is inserted with in the middle of microchannel often rolling over；In the first folding microchannel inlet, the first folding microchannel and the second folding microchannel intersection, all it is coated with powered electrode in the second folding microchannel and the 3rd folding microchannel intersection, the 3rd exit, folding microchannel.Induction EOF Micropump is put in mixing microchannel by this utility model, both the combination of Micropump and micro-mixer had been achieved, simultaneously according to the phenomenon of induction EOF, utilize the vortex produced near induction electric double layer, further the solution in microring array passage is sufficiently mixed uniformly, this utility model drives obvious with mixed effect, and simple in construction is easily manufactured.
Description
Technical field
This utility model belongs to microelectromechanical systems field, relates to a kind of micro-fluidic chip, particularly relate to a kind of for
Drive and the micro-fluidic chip of mixed solution.
Background technology
Micro-fluid chip is a kind of based on biotechnology and analytical chemistry, relates to electrochemistry, life sciences, material
The multiple ambit cross-application such as, micro-processing technology, optics, electronics, Heat Transfer and hydrodynamics, with micro-pipe
Road network is architectural feature, is currently mainly applied to the analytical tool of the novel concept of biochemical analysis field.Micro-fluid chip is real
Test room by mixing, react, separate and the functional unit such as detection forming, with microchannel network as version, microfluid
Flowing is the determiner detecting sample transport between unit.
Pump valve system is fluid operated important way, and good Micropump is designed to guarantee that fluid is easily controllable, improves
The efficiency of whole detection process, the design of micro-valve is then to solve to use the valve with movable part to answer on micro chip
Transport and raw problem.It is relatively low that microfluidic flow has Reynolds number, and with the feature that laminar flow is main nowed forming, this is all unfavorable for stream
The mixing of body, it is achieved the effectively mixing of fluid is one of fluid operated important content.
Summary of the invention
The purpose of this utility model is in fluid drives and the deficiency in mixing for current micro-fluidic chip, proposes one
New micro-fluidic chip, this micro-fluidic chip combines Micropump and micro-mixer principle, is provided simultaneously with fluid drives and mixing
Function.
In order to realize above-mentioned utility model purpose, the technical solution adopted in the utility model is as follows: a kind of solution that is used for drives
Move and the micro-fluidic chip mixed, including glass negative and the PDMS cover plate being fixed on glass negative, on described PDMS cover plate
Being provided with three folding zigzag microchannels, the import department in the first folding microchannel has two feed pathway, Y-shaped structure, and two are entered
Liquid passage connects the first sample inlet and the second sample inlet respectively, and the 3rd folding microchannel outlet connects sample export；First
Folding is inserted with the first evoked electrode in the middle of microchannel, is inserted with the second evoked electrode in the middle of the second folding microchannel, micro-logical at the 3rd folding
The 3rd evoked electrode it is inserted with in the middle of road；The glass negative of the first folding microchannel inlet is coated with the first powered electrode,
It is coated with the second powered electrode, in the second folding microchannel and on the glass negative of one folding microchannel and the second folding microchannel intersection
It is coated with the 3rd powered electrode, on the glass negative in the 3rd exit, folding microchannel on the glass negative of three folding microchannel intersections
It is coated with the 4th powered electrode.
Further, described first powered electrode, the second powered electrode, the 3rd powered electrode and the 4th powered electrode are lazy
Property metal.
Further, described first evoked electrode, the second evoked electrode and the 3rd evoked electrode are cylindrical electrode, and one
Half polarizable half is the most polarizable；On first powered electrode, the second powered electrode, the 3rd powered electrode and the 4th powered electrode
Voltage from high to low, polarizable part just powered electrode to high potential, the just energising to low potential of non-polarizable part
Electrode.
Further, described microchannel is micro scale channel.
This utility model compared with prior art, has the advantage that:
Micropump is seldom combined by the most existing microfluidic chip structure with micro-mixer, Micropump and micro-mixer
On the one hand separate and increase the size of chip and be unfavorable for the miniaturization of chip；On the other hand increase due to the existence for blender
The power that Micropump drives.This utility model devises the structure that a kind of new Micropump is combined with micro-mixer, reduces micro-fluidic
The size of chip, improves and drives and the effect of mixing.
The most existing micro fluid dynamcis mode mainly has pressure-driven and driven by electroosmosis, but pressure-driven is to micro-fluidic core
The material requirements height of sheet is unfavorable for industrialized development, simultaneously it cannot be guaranteed that the stability of flowing, can cause a certain degree of pulsation,
It is not easy to the transmission of sample.And although driven by electroosmosis has low cost, efficiency is high, the life-span is long, system structure is simple, it is simple to operation
Control, it is easy to the advantage such as integrated, but this kind drives required voltage to reach hundreds and thousands of volt, for microelectromechanical systems
The highest voltage of very difficult offer drives microfluid.This utility model is respectively adopted induction EOF at three mixing sections and drives
Dynamic, this type of drive utilizes the principle of induction electric double layer to drive microfluid, the advantage having possessed driven by electroosmosis, overcomes electricity simultaneously
Ooze the high-tension requirement of driving, greatly reduce the voltage driven needed for microfluid.
3., in induction EOF Micropump is put into mixing microchannel by this utility model, Micropump and micro-mixer had both been achieved
Combination, simultaneously according to the phenomenon of induction EOF, utilize the vortex produced near induction electric double layer, further microring array led to
Solution in road is sufficiently mixed uniformly, and this utility model drives obvious with mixed effect, and simple in construction is easily manufactured.
Accompanying drawing explanation
Fig. 1 is the top view of micro-fluidic chip；
Fig. 2 is micro-fluidic chip design sketch；
Fig. 3 is the evoked electrode used in micro-fluidic chip；
In figure: glass negative 1, PDMS cover plate the 2, first sample inlet the 3, second sample inlet 4, sample export 5, first lead to
Electricity electrode the 6, second powered electrode the 7, the 3rd powered electrode the 8, the 4th powered electrode the 9, first evoked electrode the 10, second evoked electrode
11, the 3rd evoked electrode 12, mix with drive passage 13, polarizable material 14, not polarizable material 15.
Detailed description of the invention
With specific embodiment, this utility model is described in further detail below in conjunction with the accompanying drawings.
As shown in Figure 1, 2, what this utility model provided is a kind of for solution driving and the micro-fluidic chip mixed, including glass
Glass egative film 1 and the PDMS cover plate 2 being fixed on glass negative 1, described PDMS cover plate 2 is provided with three folding zigzag microchannels 13,
Described microchannel 13 is micro scale channel, and the import department in the first folding microchannel has two feed pathway, Y-shaped structure, two
Individual feed pathway connects the first sample inlet 3 and the second sample inlet 4 respectively, and the 3rd folding microchannel outlet connects sample export 5；
In the middle of the first folding microchannel, it is inserted with the first evoked electrode 10, in the middle of the second folding microchannel, is inserted with the second evoked electrode 11,
It is inserted with the 3rd evoked electrode 12 in the middle of 3rd folding microchannel；The glass negative 1 of the first folding microchannel inlet is coated with first
Powered electrode 6, is coated with the second powered electrode 7 on the glass negative 1 of the first folding microchannel and the second folding microchannel intersection,
It is coated with the 3rd powered electrode 8, in the 3rd folding microchannel on the glass negative 1 of the second folding microchannel and the 3rd folding microchannel intersection
Being coated with the 4th powered electrode 9 on the glass negative 1 in exit, powered electrode uses vacuum sputtering.
Described first powered electrode the 6, second powered electrode the 7, the 3rd powered electrode 8 and the 4th powered electrode 9 are inertia gold
Belong to, be plated on glass negative 1 by MEMS processing technology.
As it is shown on figure 3, described first evoked electrode the 10, second evoked electrode 11 and the 3rd evoked electrode 12 are cylinder
Electrode, evoked electrode by semi-cylindrical polarizable material 14 and not polarizable material 15 form；First powered electrode 6, second
From high to low, polarizable part is just to high potential for voltage on powered electrode the 7, the 3rd powered electrode 8 and the 4th powered electrode 9
Powered electrode, non-polarizable part just powered electrode to low potential.
When experiment, filling electrolyte solution in microchannel, the first sample inlet 3 and the second sample inlet 4 two are molten
Liquid import connects two different liquid baths respectively, respectively first powered electrode the 6, second powered electrode the 7, the 3rd powered electrode 8,
Plus voltage from high to low on 4th powered electrode 9, can quilt by the principle of induction EOF microfluid in microchannel 13
Drive, by changing first powered electrode the 6, second powered electrode the 7, the 3rd powered electrode the 8, the 4th powered electrode 9 electrode two-by-two
Between electric potential difference change in microchannel 13 uninterrupted of microfluid.First sample inlet 3 and the second sample inlet 4 connect
Two liquid baths in electrolyte solution separately flow into hybrid channel in mix, according to induction EOF principle,
Produce vortex near first evoked electrode the 10, second evoked electrode 11 and the 3rd evoked electrode 12 to be mixed by solution further, greatly
Reduce greatly the length of hybrid channel, eventually pass the solution after being sufficiently mixed and flow out from sample export 5.
Claims (4)
1. one kind drives and the micro-fluidic chip mixed for solution, it is characterised in that includes glass negative (1) and is fixed on glass
PDMS cover plate (2) on glass egative film (1), described PDMS cover plate (2) is provided with three folding zigzag microchannels (13), micro-at the first folding
The import department of passage has two feed pathway, Y-shaped structure, two feed pathway connect respectively the first sample inlet (3) and
Second sample inlet (4), the 3rd folding microchannel outlet connects sample export (5)；In the middle of the first folding microchannel, it is inserted with first lure
Conductive electrode (10), is inserted with the second evoked electrode (11) in the middle of the second folding microchannel, is inserted with the 3rd in the middle of the 3rd folding microchannel
Evoked electrode (12)；The glass negative (1) of the first folding microchannel inlet is coated with the first powered electrode (6), at the first folding
Be coated with the second powered electrode (7) on the glass negative (1) of microchannel and the second folding microchannel intersection, in the second folding microchannel and
It is coated with the 3rd powered electrode (8), at the glass in the 3rd exit, folding microchannel on the glass negative (1) of the 3rd folding microchannel intersection
The 4th powered electrode (9) it is coated with on glass egative film (1).
The most according to claim 1 a kind of drive and the micro-fluidic chip mixed for solution, it is characterised in that described the
One powered electrode (6), the second powered electrode (7), the 3rd powered electrode (8) and the 4th powered electrode (9) are inert metal.
The most according to claim 1 a kind of drive and the micro-fluidic chip mixed for solution, it is characterised in that described the
One evoked electrode (10), the second evoked electrode (11) and the 3rd evoked electrode (12) are cylindrical electrode, half polarizable
The most polarizable；On first powered electrode (6), the second powered electrode (7), the 3rd powered electrode (8) and the 4th powered electrode (9)
Voltage from high to low, polarizable part just powered electrode to high potential, low potential is just led to by non-polarizable part
Electricity electrode.
The most according to claim 1 a kind of for solution driving and the micro-fluidic chip mixed, it is characterised in that described micro-
Passage (13) is micro scale channel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620562239.2U CN205691537U (en) | 2016-06-12 | 2016-06-12 | A kind of for solution driving and the micro-fluidic chip mixed |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620562239.2U CN205691537U (en) | 2016-06-12 | 2016-06-12 | A kind of for solution driving and the micro-fluidic chip mixed |
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| Publication Number | Publication Date |
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| CN205691537U true CN205691537U (en) | 2016-11-16 |
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| CN201620562239.2U Expired - Fee Related CN205691537U (en) | 2016-06-12 | 2016-06-12 | A kind of for solution driving and the micro-fluidic chip mixed |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106908484A (en) * | 2017-01-18 | 2017-06-30 | 江苏大学 | A kind of apparatus and method of detection Y type paperys microchannel mixing efficiency |
| CN110330393A (en) * | 2019-07-17 | 2019-10-15 | 南京理工大学 | A kind of nanometer grade explosive preparation system and method based on passive type micro-mixer |
| CN110947329A (en) * | 2019-11-29 | 2020-04-03 | 南昌航空大学 | Sawtooth type passive micro mixer |
| CN113522381A (en) * | 2021-05-26 | 2021-10-22 | 西北工业大学太仓长三角研究院 | Different concentration liquid drop produces chip based on induction charge electroosmosis |
-
2016
- 2016-06-12 CN CN201620562239.2U patent/CN205691537U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106908484A (en) * | 2017-01-18 | 2017-06-30 | 江苏大学 | A kind of apparatus and method of detection Y type paperys microchannel mixing efficiency |
| CN110330393A (en) * | 2019-07-17 | 2019-10-15 | 南京理工大学 | A kind of nanometer grade explosive preparation system and method based on passive type micro-mixer |
| CN110330393B (en) * | 2019-07-17 | 2021-11-30 | 南京理工大学 | Nano explosive preparation system and method based on passive micro mixer |
| CN110947329A (en) * | 2019-11-29 | 2020-04-03 | 南昌航空大学 | Sawtooth type passive micro mixer |
| CN113522381A (en) * | 2021-05-26 | 2021-10-22 | 西北工业大学太仓长三角研究院 | Different concentration liquid drop produces chip based on induction charge electroosmosis |
| CN113522381B (en) * | 2021-05-26 | 2022-11-15 | 西北工业大学太仓长三角研究院 | Different concentration liquid drop produces chip based on induction charge electroosmosis |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161116 Termination date: 20170612 |
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| CF01 | Termination of patent right due to non-payment of annual fee |