CN117083054A - 用于治疗过敏反应的装置 - Google Patents
用于治疗过敏反应的装置 Download PDFInfo
- Publication number
- CN117083054A CN117083054A CN202280024727.6A CN202280024727A CN117083054A CN 117083054 A CN117083054 A CN 117083054A CN 202280024727 A CN202280024727 A CN 202280024727A CN 117083054 A CN117083054 A CN 117083054A
- Authority
- CN
- China
- Prior art keywords
- epinephrine
- dose inhaler
- formulation
- metered dose
- pressurized metered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/003—Particle size control by passing the aerosol trough sieves or filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C19/00—Acyclic saturated compounds containing halogen atoms
- C07C19/08—Acyclic saturated compounds containing halogen atoms containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/02—Equipment for testing the apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Surgical Instruments (AREA)
- Non-Portable Lighting Devices Or Systems Thereof (AREA)
- Processing Of Meat And Fish (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163165102P | 2021-03-23 | 2021-03-23 | |
| US63/165,102 | 2021-03-23 | ||
| PCT/US2022/021612 WO2022204328A1 (en) | 2021-03-23 | 2022-03-23 | Device for treating anaphylaxis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117083054A true CN117083054A (zh) | 2023-11-17 |
Family
ID=81307871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202280024727.6A Pending CN117083054A (zh) | 2021-03-23 | 2022-03-23 | 用于治疗过敏反应的装置 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20220331237A1 (https=) |
| EP (2) | EP4188332B1 (https=) |
| JP (1) | JP2024515446A (https=) |
| KR (1) | KR20230165764A (https=) |
| CN (1) | CN117083054A (https=) |
| AU (1) | AU2022245300B2 (https=) |
| BR (1) | BR112023019156A2 (https=) |
| CA (1) | CA3212189A1 (https=) |
| DK (1) | DK4188332T3 (https=) |
| ES (1) | ES3025005T3 (https=) |
| FI (1) | FI4188332T3 (https=) |
| HR (1) | HRP20250566T1 (https=) |
| HU (1) | HUE071185T2 (https=) |
| IL (1) | IL305534A (https=) |
| LT (1) | LT4188332T (https=) |
| PL (1) | PL4188332T3 (https=) |
| PT (1) | PT4188332T (https=) |
| RS (1) | RS66787B1 (https=) |
| SI (1) | SI4188332T1 (https=) |
| WO (1) | WO2022204328A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12514995B2 (en) * | 2021-02-15 | 2026-01-06 | Glenmark Pharmaceuticals Limited | Metered dose inhalers of fluticasone or an ester thereof |
| WO2025072756A1 (en) * | 2023-09-28 | 2025-04-03 | Kokua Pharma Inc. | Device, methods, and uses for treating acute allergic reactions |
| WO2025170986A1 (en) * | 2024-02-06 | 2025-08-14 | Kindeva Drug Delivery L.P. | Drug delivery device |
| US20260007598A1 (en) * | 2024-07-05 | 2026-01-08 | Honeywell International Inc. | Compositions, devices and methods for respritory delivery of active pharmaceutical ingredients |
| US12496272B1 (en) * | 2024-07-31 | 2025-12-16 | Amphastar Pharmaceuticals, Inc. | Stable epinephrine suspension formulation for inhalation with HFO propellant |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9324250D0 (en) * | 1993-11-25 | 1994-01-12 | Minnesota Mining & Mfg | Inhaler |
| EP1321159A1 (en) | 2001-12-21 | 2003-06-25 | CHIESI FARMACEUTICI S.p.A. | Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices |
| SI1531794T1 (sl) | 2002-06-28 | 2017-12-29 | Civitas Therapeteutics, Inc. | Epinefrin za vdihavanje |
| US7954491B2 (en) * | 2003-06-13 | 2011-06-07 | Civitas Therapeutics, Inc. | Low dose pharmaceutical powders for inhalations |
| WO2006101882A2 (en) * | 2005-03-16 | 2006-09-28 | Honeywell International Inc. | Medicament delivery formulations, devices and methods |
| US8367734B1 (en) * | 2005-08-11 | 2013-02-05 | Amphastar Pharmaceuticals Inc. | Stable epinephrine suspension formulation with high inhalation delivery efficiency |
| GB0801876D0 (en) * | 2008-02-01 | 2008-03-12 | Vectura Group Plc | Suspension formulations |
| PT2627386E (pt) * | 2010-10-12 | 2015-06-11 | Ivax Pharmaceuticals Ireland | Dispositivo de pulverização nasal |
| US20120204871A1 (en) * | 2011-02-10 | 2012-08-16 | Julio Cesar Vega | Stable, non-corrosive formulations for pressurized metered dose inhalers |
| KR20150048727A (ko) * | 2012-08-29 | 2015-05-07 | 키에시 파르마슈티시 엣스. 피. 에이. | 에어로졸 흡입 장치 |
| US10039710B2 (en) * | 2015-09-18 | 2018-08-07 | Insys Development Company, Inc. | Epinephrine spray formulations |
| US9717683B1 (en) * | 2016-06-29 | 2017-08-01 | Ep Pharma, Llc | Low-temperature inhalation administration of cannabinoid entities |
-
2022
- 2022-03-23 US US17/702,733 patent/US20220331237A1/en active Pending
- 2022-03-23 EP EP22716648.5A patent/EP4188332B1/en active Active
- 2022-03-23 PT PT227166485T patent/PT4188332T/pt unknown
- 2022-03-23 HR HRP20250566TT patent/HRP20250566T1/hr unknown
- 2022-03-23 EP EP24223644.6A patent/EP4545122A3/en active Pending
- 2022-03-23 IL IL305534A patent/IL305534A/en unknown
- 2022-03-23 HU HUE22716648A patent/HUE071185T2/hu unknown
- 2022-03-23 LT LTEPPCT/US2022/021612T patent/LT4188332T/lt unknown
- 2022-03-23 RS RS20250407A patent/RS66787B1/sr unknown
- 2022-03-23 FI FIEP22716648.5T patent/FI4188332T3/fi active
- 2022-03-23 KR KR1020237032955A patent/KR20230165764A/ko not_active Ceased
- 2022-03-23 DK DK22716648.5T patent/DK4188332T3/da active
- 2022-03-23 CA CA3212189A patent/CA3212189A1/en active Pending
- 2022-03-23 BR BR112023019156A patent/BR112023019156A2/pt unknown
- 2022-03-23 AU AU2022245300A patent/AU2022245300B2/en active Active
- 2022-03-23 SI SI202230117T patent/SI4188332T1/sl unknown
- 2022-03-23 CN CN202280024727.6A patent/CN117083054A/zh active Pending
- 2022-03-23 WO PCT/US2022/021612 patent/WO2022204328A1/en not_active Ceased
- 2022-03-23 JP JP2023557007A patent/JP2024515446A/ja active Pending
- 2022-03-23 ES ES22716648T patent/ES3025005T3/es active Active
- 2022-03-23 PL PL22716648.5T patent/PL4188332T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4188332B1 (en) | 2025-02-12 |
| WO2022204328A1 (en) | 2022-09-29 |
| PT4188332T (pt) | 2025-04-17 |
| BR112023019156A2 (pt) | 2023-10-17 |
| HUE071185T2 (hu) | 2025-08-28 |
| LT4188332T (lt) | 2025-05-12 |
| US20220331237A1 (en) | 2022-10-20 |
| FI4188332T3 (fi) | 2025-05-06 |
| ES3025005T3 (en) | 2025-06-05 |
| JP2024515446A (ja) | 2024-04-10 |
| SI4188332T1 (sl) | 2025-07-31 |
| KR20230165764A (ko) | 2023-12-05 |
| AU2022245300B2 (en) | 2026-04-02 |
| RS66787B1 (sr) | 2025-06-30 |
| CA3212189A1 (en) | 2022-09-29 |
| EP4188332A1 (en) | 2023-06-07 |
| DK4188332T3 (da) | 2025-05-05 |
| AU2022245300A1 (en) | 2023-09-14 |
| EP4545122A2 (en) | 2025-04-30 |
| PL4188332T3 (pl) | 2025-11-24 |
| HRP20250566T1 (hr) | 2025-06-20 |
| EP4545122A3 (en) | 2025-05-07 |
| IL305534A (en) | 2023-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 40102631 Country of ref document: HK |
|
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Country or region after: Canada Address after: British Columbia Applicant after: Koukua Pharmaceutical Co.,Ltd. Address before: British Columbia Applicant before: 1232176 B.C. Ltd. Country or region before: Canada |