CN116942775A - 一种促进脑和身高发育兼具抑制性早熟的制剂及制备方法和应用 - Google Patents
一种促进脑和身高发育兼具抑制性早熟的制剂及制备方法和应用 Download PDFInfo
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Abstract
本发明公开了一种促进脑和身高发育兼具抑制性早熟的制剂及制备方法和应用,属于中医药技术领域。该制剂是由百合、薄荷、砂仁、酸枣仁、陈皮、覆盆子、龙眼肉、黑枣、黄精、藿香、桔梗、莲子、桑椹、山楂、桃仁、杏仁、益智仁、郁李仁、淡竹叶、紫苏、核桃组配而成,不仅能够促进儿童、青少年长高发育和大脑发育,对于部分出现发育过猛,也能抑制性早熟,实现促进发育和抑制过分成熟的双向调节。全部采用药食同源原料,专门增加了代谢儿童、青少年体内因饮食问题造成的农药残留、添加剂残留等问题的配方,且是在综合中医中药学大量经验与研究后,结合现代生物学、儿医学的最新理论,对药食同源进行了一次创造性的使用。
Description
技术领域
本发明属于中医药技术领域,具体涉及一种促进脑和身高发育兼具抑制性早熟的制剂及制备方法和应用。
背景技术
现有促进儿童、青少年脑发育和身高发育的产品,多在益生菌领域、菌株领域、奶制品领域、鱼肝油等领域内,多为通过胃肠道菌群调节,或者口服或者注射微量元素、生长激素等方法,没有调动儿童、青少年本身体内自有的生机结构。且一些生长激素为化学类制剂只考虑增高,对其他健康因素的影响、代谢效率低等及其他副作用问题。还有一些生物干预技术治疗费用高昂,多数家庭都不容易负担,更何况广大农村地区适龄儿童的家庭。
以及现在因为饮食结构、水质土壤等环境污染、抗生素含量超标等问题,一些儿童出现脑发育不足的问题,而另一些儿童则出现发育过早、过胖、性早熟的问题。加上现在学习压力大,很多青少年在成长过程中的情致得不到舒展,身体发育也受到抑制。
中医和药食同源是中华民族的瑰宝,也有相关产品研究,但目前这些产品还要涉及中药材,涉及处方。且目前市面上的产品,要么是针对促进生长发育开发的产品,要么是针对儿童、青少年抑制性早熟开发的产品,没有开发出一个产品能够双效调节发育不足或发育过猛的问题。
发明内容
本发明的目的在于提供一种促进脑和身高发育兼具抑制性早熟的制剂,该制剂不仅能够促进儿童、青少年长高发育和大脑发育,对于部分儿童、青少年出现的发育过猛、发育太过,该制剂也能抑制性早熟,实现促进发育和抑制过分成熟的双向调节的作用。
本发明的第二目的在于提供一种促进脑和身高发育兼具抑制性早熟的制剂,该制剂全部采用药食同源原料,全部为食品,能涵盖更多的家庭和生产方,并且专门增加了代谢儿童、青少年体内因饮食问题造成的农药残留、添加剂残留等问题的配方,且是在综合中医中药学大量经验与研究后,结合现代生物学、儿医学的最新理论,对药食同源进行了一次创造性的使用。
本发明通过以下技术方案实现:
一种促进脑和身高发育兼具抑制性早熟的制剂,所述制剂主要由以下质量份数的原料制备得到:
百合9-30份、薄荷4-25份、砂仁1-20份、酸枣仁4-25份、陈皮6-27份、覆盆子0.5-18份、龙眼肉3-22份、黑枣4-23份、黄精0.5-18份、藿香0.5-18份、桔梗9-30份、莲子5-26份、桑椹5-26份、山楂1-20份、桃仁0.6-16份、杏仁0.6-16份、益智仁4-25份、郁李仁4-23份、淡竹叶4-23份、紫苏2-21份、核桃8-28份。
上述提供了一种促进脑和身高发育兼具抑制性早熟的制剂的组方配伍,其适用于儿童和青少年。该组方从先天资本肝肾和后天资本脾胃入手,对儿童心智系统进行了一个全方位的照顾。郁李仁,解郁、调节情志,益智仁,可以开发脑细胞,疏通大脑微循环;酸枣仁,可以补心脏,心脑同源;百合、核桃、龙眼肉,按照搭配的组合份数,不仅补脑,有补有开有通,把肾的能量,通过肝的疏导作用输送到大脑上去,长养脑细胞;桑椹、陈皮、砂仁、覆盆子,按照搭配的组合份数,可以补肝肾,同时健脾胃。常规补药比较难吸收,使用搭配的紫苏,能够健脾胃,并把体内多余的垃圾能量排出去;黄精,气血阴阳都补,配合搭配的砂仁,健脾理气,还有化湿的作用,能增强了这些药食同源的吸收。儿童、青少年在生长发育过程中,生机很旺,遇到外在压力容易肝郁,用陈皮、桔梗、藿香的搭配份数,能把郁滞的能量打开,让儿童、青少年原本的系统又重新焕发生机勃勃的功能。桔梗还有宣发肺气的作用,儿童、青少年在发育过程中肺常不足,使用的陈皮、桔梗、藿香的搭配份数,芳香化湿健脾温中,能把上焦和下焦之间沟通的枢纽给打开连接起来,转开消化系统。莲子、淡竹叶和薄荷搭配的组方,可以清心降虚火,降虚火的作用可以让儿童、青少年在成长过程中,面对外界压力时不至于躁郁、冲动,它能把人体的邪火给泄掉,有解结、散结的作用,散开之后给人体留出空间,再结合上面芳香化湿健脾温中的组方,就能从肝肾,从根上给儿童、青少年进行精气神的补充,但是都知道要补充人体的精气神,先天后天形成一个生生不息的循环,供到机体大脑神经系统,帮助儿童、青少年健康发育,身心舒展。
作为优选地,所述制剂主要由以下质量份数的原料制备得到:
百合14-25份、薄荷9-20份、砂仁5-15份、酸枣仁9-20份、陈皮11-22份、覆盆子4-14份、龙眼肉7-17份、黑枣8-18份、黄精4-14份、藿香4-14份、桔梗14-25份、莲子10-21份、桑椹10-21份、山楂5-15份、桃仁1-11份、杏仁1-11份、益智仁9-20份、郁李仁8-18份、淡竹叶8-18份、紫苏6-16份、核桃13-24份。
作为优选地,所述制剂主要由以下质量份数的原料制备得到:
百合19份、薄荷14份、砂仁10份、酸枣仁14份、陈皮16份、覆盆子9份、龙眼肉12份、黑枣13份、黄精9份、藿香9份、桔梗19份、莲子15份、桑椹15份、山楂10份、桃仁6份、杏仁6份、益智仁14份、郁李仁13份、淡竹叶13份、紫苏11份、核桃18份。
上述桑椹、陈皮、砂仁、覆盆子、紫苏、藿香、桔梗,该配比能够健脾胃,强肝肾,打开上焦和下焦之间沟通的枢纽,并把体内多余的垃圾能量排出去,留出空间,解决常规补药比较难吸收的问题,同时能把儿童、青少年体内郁滞的能量打开。莲子、淡竹叶和薄荷搭配的组方,有效的针对儿童、青少年的发育特点来清心降虚火,让儿童、青少年在成长过程中,面对外界压力时不至于躁郁、冲动,有泄邪火、解结、散结的作用。百合、核桃、龙眼肉,这个配比不仅补脑,有补有开有通,把肾的能量,通过肝的疏导作用输送到大脑上去,长养脑细胞。
百合,中药名。为百合科百合属植物百合Lilium brownii F.E.Brownvar.viridulium baker或细叶百合L.Pumilum DC.的肉质鳞叶。具有养阴润肺,清心安神的功效。主治阴虚燥咳,劳嗽咳血,阴虚有热之失眠心悸及百合病心肺阴虚内热证味甘,性微寒;归肺、心、胃经。本品含酚酸甘油酯、丙酸酯衍生物、酚酸的糖苷、酚酸甘油酯糖苷、甾体糖苷、甾体生物碱、微量元素、淀粉、蛋白质、脂肪等成分。
薄荷,中药名。为唇形科薄荷属植物薄荷Mentha haplocalyx Briq.的地上部分。具有疏散风热,清利头目,利咽透疹,疏肝行气的功效。主治风热感冒,温病初起,风热头痛,目赤多泪,咽喉肿痛,麻疹不透,风疹瘙痒,肝郁气滞、胸闷胁痛。味辛,性凉;归肺、肝经。本品主含挥发油。油中主要成分为薄荷醇、薄荷酮、异薄荷酮、薄荷脑、薄荷酯类等多种成分。另含异端叶灵、薄荷糖苷及多种游离氨基酸等。
砂仁,中药名。为姜科砂仁属植物阳春砂Amomum villosum Lour.、绿壳砂Amomumvillosum Lour.var.xanthioides T.L.Wu et Senjen或海南砂Amomum longiligulareT.L.Wu的干燥成熟果实。具有化湿行气,温中止泻,安胎的功效。主治脾胃气滞、湿阻中焦、脾胃虚寒、呕吐泻泄、胎动不安、妊娠恶阻等味辛,性温;归脾、胃、肾经。阳春砂含挥发油,油中主要成分为右旋樟脑、龙脑、乙酸龙脑酯、柠檬烯、橙花叔醇等,并含皂苷。
酸枣仁,中药名。为鼠李科枣属植物酸枣Ziziphus jujuba Mill.var.spinosa(Bunge)Hu ex H.F.Chou的成熟种子。具有养心益肝,安神,敛汗的功效。主要用于血虚心悸、怔忡、健忘、失眠、多梦、眩晕,体虚自汗、盗汗及津伤口渴咽干等味甘、酸,性平、温;归心经。本品多含脂肪油和蛋白质,并有两种甾醇,两种三萜化合物(白桦脂醇、白桦脂酸),酸枣仁皂甙,还有多量维生素C。
陈皮,中药名。为芸香科柑橘属植物橘Citrus reticulata Blanco及其栽培变种的干燥成熟果皮。具有理气健脾,燥湿化痰的功效。主治脾胃气滞证,呕吐,呃逆,湿痰,寒痰咳嗽,胸痹。味辛、苦,性温;归脾、肺经。陈皮中含有川陈皮素、橙皮苷、新橙皮苷、橙皮素、对羟福林、黄酮化合物等。陈皮挥发油含量为1.5%-2.0%,广陈皮挥发油含量为1.2%-3.2%,其成分有α-侧柏烯、柠檬烯等。
覆盆子,中药名。为蔷薇科悬钩子属植物华东覆盆子Rubus chingii Hu的未成熟果实。具有固精缩尿,益肝肾明目的功效。主治肾气不足,下元虚冷而致遗精、滑精、遗尿、尿频、阳痿、不孕,以及肝肾不足、两目昏花、视物不清等。味甘、酸,性微温;归肝、肾经。覆盆子含有机酸、糖类及少量维生素C,果实中还含有三萜成分、覆盆子酸、鞣花酸和β-谷甾醇。
龙眼肉,中药名。为无患子科龙眼属植物龙眼Dimocarpus longan Lour.的假种皮。具有补益心脾,养血安神的功效。主治思虑过度,劳伤心脾,惊悸怔忡,失眠健忘。味甘,性温;归心、脾经。龙眼肉含水溶性物质、不溶性物质、灰分。可溶性物质含葡萄糖,还含有蛋白质、脂肪以及维生素B1、B2、P、C等。
黑枣,具有补中益气,养胃健脾,养血壮神,润心肺,调营卫、生津液,悦颜色,通九窍,助十二经,解药毒,调和百药的作用。入脾胃经,能补中益气、养血、安神及明目。多用于补血和作为调理药物,对贫血、血小板减少、肝炎、乏力、失眠有一定疗效。野生大黑枣,药用干品,大约180-130颗/斤。根据现代药理研究:黑枣含有葡萄糖、果糖、蔗糖、维生素c、核黄素、胡萝卜素、13种氨基酸和36种微量元素等,堪称"天然的综合维生素丸",对于少年阶段视力保健有极佳的效果。
黄精,中药名。为百合科黄精属植物黄精Polygonatum sibiricum Red.、多花黄精Polygonatum cyrtonema Hua或滇黄精Polygonatum kingianum Coll.et Hemsl.的干燥根茎。具有养阴润肺,补脾益气,滋肾填精的功效。主治阴虚劳嗽,肺燥咳嗷,脾虚乏力,食少口干,消渴;肾亏腰膝酸软,阳痿遗精,耳鸣目暗,须发早白,体虚羸瘦,风癞癣疾。味甘,性平;归脾、肺、肾经。含黏液质、淀粉、糖、烟酸、醌类。多花黄精含二氨基丁酸、天门冬氨酸、高丝氨酸、毛地黄糖苷及多种蒽醌类化合物。
藿香,中药名。为唇形科藿香属植物广藿香Pogostemon cablin(Blanco)Benth.的地上部分。具有化湿,止呕,解暑的功效。主治湿阻中焦,呕吐,暑湿或湿温初起味辛,性微温;归脾、胃、肺经含挥发油约1.5%,油中主要成分为广藿香醇,其他成分有苯甲醛、丁香油酚、桂皮醛等。另有多种其他倍半萜如竹烯等。尚含生物碱类。
桔梗,中药名。为桔梗科桔梗属植物桔梗Platycodon grandiflorus(Jacq.)A.DC.的干燥根。具有宣肺,祛痰,利咽,排脓的功效。主治咳嗽痰多,胸闷不畅,咽喉肿痛,失音,肺痈吐脓,味苦、辛,性平;归肺经本品含多种皂苷,主要为桔梗皂苷,多种混合皂苷经完全水解所产生的皂苷元有桔梗皂苷元,远志酸,以及少量的桔梗酸。另外还含菊糖、植物甾醇等。
莲子,中药名。为睡莲科莲属植物莲Nelumbo nucifera Gaertn.的成熟种子。具有固精止带,补脾止泻,益肾养心的功效。主治脾虚久泻,食欲不振,肾气不足,精关不固之遗精滑精或心肾不交之小便白浊,梦遗滑精,脾虚失运,水湿下注之带下证以及心肾不交,虚烦失眠。味甘、涩,性平;归脾、肾、心经。本品主含淀粉、蛋白质、脂肪、碳水化合物、棉子糖、钙、磷、铁等。
桑椹,中药名。为桑科桑属植物桑Morus alba L.的果穗。具有滋阴补血,生津润肠的功效。主治眩晕耳鸣,须发早白,血虚经闭,津伤口渴,内热消渴,肠燥便秘等。味甘、酸,性寒;归心、肝、肾经。化学成分:含芸香苷、花青素苷、胡萝卜素、维生素B1、维生素B2、维生素C及糖类。尚含脂肪油,其中主要成分为亚油酸、少量硬脂酸和油酸。
山楂,中药名。为蔷薇科山楂属植物山里红Crataegus pinnatiidaBge.var.major N.E.Br.或山楂Crataegus pinnatifida Bge.的干燥成熟果实。具有消食化积,行气散瘀的功效。主治饮食积滞,泻痢腹痛,疝气痛,瘀阻胸腹痛,痛经味酸、甘,性微温;归脾、胃。山楂含黄酮类、三萜皂苷类(熊果酸、齐墩果酸、山楂酸等),皂苷鞣质、游离酸、脂肪酸、维生素C、无机盐、红色素。
桃仁,中药名。为蔷薇科桃属植物桃Prunus persica(L.)Batsch或山桃Prunusdavidiana(Carr.)Franch.的干燥成熟种子。果实成熟后采收,除去果肉和核壳,取出种子,晒干。全国各地普遍栽培。具有活血祛瘀,润肠通便,止咳平喘的功效。主治经闭痛经,癥瘕痞块,肺痈肠痈,跌扑损伤,肠燥便秘,咳嗽气喘。味苦、甘,性平;归心、肝、大肠,含苦杏仁苷、苦杏仁酶、挥发油、脂肪油(油酸甘油酯、亚油酸甘油酯)等。
杏仁,中药名。为蔷薇科杏属植物杏Armeniaca vulgaris Lam.[Prunusarmeniaca L.]、野杏A.vulgaris Lam.var.ansu(Maxim)Yu et Lu[Prunus armeniacaL.var.ansu Maxim.]、山杏A.sibirica(L.)Lam.[Prunus sibirica L.]、东北杏A.mandshurica(Maxim.)Skv.[Prunus mandshurica(Maxim.)Koehne]的种子。具有止咳平喘,润肠通便的功效。主治咳嗽气喘,胸满痰多,血虚津枯,肠燥便秘杏核仁、杏子、木落子、苦杏仁。本品含苦杏仁苷及脂肪油、蛋白质、各种游离氨基酸。尚含苦杏仁酶、苦杏仁苷酶、绿原酸、肌醇、苯甲醛、芳樟醇等。
益智仁,中药名。为姜科山姜属植物益智Alpinia oxyphylla Miq.的果实。具有温脾止泻摄涎,暖肾缩尿固精的功效。主治脾胃虚寒,呕吐,泄泻,腹中冷痛,口多唾涎,肾虚遗尿,尿频,遗精,白浊。味辛,性温;归脾、肾经含二苯庚体类、类倍半萜类及挥发油。
郁李仁,中药名。为蔷薇科郁李属植物欧李Prunus humilis Bunge.、郁李Prunusjaponica Thunb.或榆叶梅Prunus triloba Lindl.、长柄扁桃Prunus pedunculataMaxim.的种仁。具有润肠通便,下气利尿消肿的功效。主治肠燥便秘,水肿胀满,脚气浮肿。味辛、苦、甘,性平;归脾经。1、郁李:种子含苦杏仁甙,郁李仁甙A、B,还分离到2种蛋白质成分IR-A和IR-B。新鲜果实含蔷薇甙A、B,即是郁李仁甙A、B,还含有熊果酸、香草酸,原儿茶酸,阿福豆甙山柰甙,野蔷薇甙A。2、欧李:种子含苦杏仁甙,郁李仁甙A、B。3、长梗郁李:种子含苦杏仁甙,郁李仁甙A、B。4、毛叶欧李:种子含苦杏仁甙,郁李仁甙A、B。
淡竹叶,中药名。为禾本科淡竹叶属植物淡竹叶Lophatherum gracile Brongn.的干燥茎叶。具有清热泻火,除烦,利尿的功效。主治热病烦渴,口疮尿赤,热淋涩痛味甘、淡,性寒;归心、胃。本品含三萜类化合物,如芦竹素、白茅素、蒲公英赛醇及甾体类物质如β-谷甾醇、豆甾醇、菜油甾醇、蒲公英甾醇等。
紫苏,中药名。为唇形科紫苏属植物紫苏Perilla frutescens(L.)Britt.的茎、叶。其叶称为紫苏叶,其茎称为紫苏梗。具有解表散寒,行气宽中,安胎,解鱼蟹毒的功效。主治风寒感冒,脾胃气滞、胸闷呕吐,胎气上逆、胎动不安,七情郁结、痰凝气滞之梅核气证,进食鱼蟹中毒而致腹痛吐泻等。味辛、辣,性微热;入冷经。含挥发油,其中主要为紫苏醛、左旋柠檬烯及少量α-蒎烯等。
核桃,味甘、性温,入肾、肺、大肠经。可补肾、固精强腰、温肺定喘、润肠通便。主治:肾虚喘嗽、腰痛;(核中木质隔层)味苦、性温;补肾,涩精。1.破血祛瘀:用于血滞经闭、血瘀腹痛、蓄血发狂、跌打瘀能等病症。2.润燥滑肠:用于肠燥便秘的大便难解。本品苦泄散瘀,入肝经血分,有较强的活血调经、祛瘀生新之功,适于血分瘀滞较重者。此外,兼有润肠、止咳之功。用于肾虚腰痛,两脚痿弱,小便频数,遗精阳痿;肺气虚弱或肺肾两虚,喘咳短气;肠燥便秘,大便干涩;石淋,小便不利等。
一种促进脑和身高发育兼具抑制性早熟的制剂的制备方法,包括如下步骤:
选取百合、薄荷、砂仁、酸枣仁、陈皮、覆盆子、龙眼肉、黑枣、黄精、藿香、桔梗、莲子、桑椹、山楂、桃仁、杏仁、益智仁、郁李仁、淡竹叶、紫苏、核桃分别经干燥、磨粉后,水提分别获得提取物后;
按照相应质量份数选取百合提取物、薄荷提取物、砂仁提取物、酸枣仁提取物、陈皮提取物、覆盆子提取物、龙眼肉提取物、黑枣提取物、黄精提取物、藿香提取物、桔梗提取物、莲子提取物、桑椹提取物、山楂提取物、桃仁提取物、杏仁提取物、益智仁提取物、郁李仁提取物、淡竹叶提取物、紫苏提取物和核桃提取物的所有提取物,混合后加入固型剂,搓丸,完成。
作为优选地,所述磨粉时控制温度为5-10℃。
作为优选地,所述固型剂为炼蜜。
作为优选地,所述固型剂是采用蜂蜜在90-100℃下熬制至冒泡粘稠状即可。
作为优选地,所述熬制时长为2-3min。
作为优选地,所述固型剂与所有提取物混合总重量的比为0.5-0.8:1。
一种促进脑和身高发育兼具抑制性早熟的制剂的应用,所述制剂在制备儿童、青少年制剂产品中的应用。
与现有技术相比,本发明至少具有如下技术效果:
本发明提供了一种促进脑和身高发育兼具抑制性早熟的制剂,该制剂不仅能够促进儿童、青少年长高发育和大脑发育,对于部分儿童、青少年出现的发育过猛、发育太过,该制剂也能抑制性早熟,实现促进发育和抑制过分成熟的双向调节的作用。
该制剂全部采用药食同源原料,全部为食品,能涵盖更多的家庭和生产方,并且专门增加了代谢儿童、青少年体内因饮食问题造成的农药残留、添加剂残留等问题的配方,且是在综合中医中药学大量经验与研究后,结合现代生物学、儿医学的最新理论,对药食同源进行了一次创造性的使用。
上述该促进脑和身高发育兼具抑制性早熟的制剂的组方配伍,其适用于儿童和青少年。该组方从先天资本肝肾和后天资本脾胃入手,对儿童心智系统进行了一个全方位的照顾。郁李仁,解郁、调节情志,益智仁,可以开发脑细胞,疏通大脑微循环;酸枣仁,可以补心脏,心脑同源;百合、核桃、龙眼肉,按照搭配的组合份数,不仅补脑,有补有开有通,把肾的能量,通过肝的疏导作用输送到大脑上去,长养脑细胞;桑椹、陈皮、砂仁、覆盆子,按照搭配的组合份数,可以补肝肾,同时健脾胃。常规补药比较难吸收,使用搭配的紫苏,能够健脾胃,并把体内多余的垃圾能量排出去;黄精,气血阴阳都补,配合搭配的砂仁,健脾理气,还有化湿的作用,能增强了这些药食同源的吸收。儿童、青少年在生长发育过程中,生机很旺,遇到外在压力容易肝郁,用陈皮、桔梗、藿香的搭配份数,能把郁滞的能量打开,让儿童、青少年原本的系统又重新焕发生机勃勃的功能。桔梗还有宣发肺气的作用,儿童、青少年在发育过程中肺常不足,使用的陈皮、桔梗、藿香的搭配份数,芳香化湿健脾温中,能把上焦和下焦之间沟通的枢纽给打开连接起来,转开消化系统。莲子、淡竹叶和薄荷搭配的组方,可以清心降虚火,降虚火的作用可以让儿童、青少年在成长过程中,面对外界压力时不至于躁郁、冲动,它能把人体的邪火给泄掉,有解结、散结的作用,散开之后给人体留出空间,再结合上面芳香化湿健脾温中的组方,就能从肝肾,从根上给儿童、青少年进行精气神的补充,但是都知道要补充人体的精气神,先天后天形成一个生生不息的循环,供到机体大脑神经系统,帮助儿童、青少年健康发育,身心舒展。
具体实施方式
下面将结合实施例对本发明的实施方案进行详细描述,但是本领域技术人员将会理解,下列实施例仅用于说明本发明,而不应视为限制本发明的范围,实施例中未注明的具体条件,按照常规条件或者制造商建议的条件进行,所用试剂或仪器未注明生产厂商者,均为可以通过市售购买获得的常规产品。
实施例1:
一种促进脑和身高发育兼具抑制性早熟的制剂,所述制剂由以下质量份数的原料制备得到:
百合9克、薄荷4克、砂仁1克、酸枣仁4克、陈皮6克、覆盆子0.5克、龙眼肉3克、黑枣4克、黄精0.5克、藿香0.5克、桔梗9克、莲子5克、桑椹5克、山楂1克、桃仁0.6克、杏仁0.6克、益智仁4克、郁李仁4克、淡竹叶4克、紫苏2克和核桃8克。
实施例2:
一种促进脑和身高发育兼具抑制性早熟的制剂,所述制剂由以下质量份数的原料制备得到:
百合30克、薄荷25克、砂仁20克、酸枣仁25克、陈皮27克、覆盆子18克、龙眼肉22克、黑枣23克、黄精18克、藿香18克、桔梗30克、莲子26克、桑椹26克、山楂20克、桃仁16克、杏仁16克、益智仁25克、郁李仁23克、淡竹叶23克、紫苏21克和核桃28克。
实施例3:
一种促进脑和身高发育兼具抑制性早熟的制剂,所述制剂由以下质量份数的原料制备得到:
百合14克、薄荷9克、砂仁5克、酸枣仁9克、陈皮11克、覆盆子4克、龙眼肉7克、黑枣8克、黄精4克、藿香4克、桔梗14克、莲子10克、桑椹10克、山楂5克、桃仁1克、杏仁1克、益智仁9克、郁李仁8克、淡竹叶8克、紫苏6克和核桃13克。
实施例4:
一种促进脑和身高发育兼具抑制性早熟的制剂,所述制剂由以下质量份数的原料制备得到:
百合25克、薄荷20克、砂仁15克、酸枣仁20克、陈皮22克、覆盆子14克、龙眼肉17克、黑枣18克、黄精14克、藿香14克、桔梗25克、莲子21克、桑椹21克、山楂15克、桃仁11克、杏仁11克、益智仁20克、郁李仁18克、淡竹叶18克、紫苏16克和核桃24克。
实施例5:
一种促进脑和身高发育兼具抑制性早熟的制剂,所述制剂由以下质量份数的原料制备得到:
百合19克、薄荷14克、砂仁10克、酸枣仁14克、陈皮16克、覆盆子9克、龙眼肉12克、黑枣13克、黄精9克、藿香9克、桔梗19克、莲子15克、桑椹15克、山楂10克、桃仁6克、杏仁6克、益智仁14克、郁李仁13克、淡竹叶13克、紫苏11克和核桃18克。
一种促进脑和身高发育兼具抑制性早熟的制剂的制备方法,包括如下步骤:
选取百合、薄荷、砂仁、酸枣仁、陈皮、覆盆子、龙眼肉、黑枣、黄精、藿香、桔梗、莲子、桑椹、山楂、桃仁、杏仁、益智仁、郁李仁、淡竹叶、紫苏、核桃分别经干燥、磨粉后,水提分别获得提取物后;
按照相应质量份数选取百合提取物、薄荷提取物、砂仁提取物、酸枣仁提取物、陈皮提取物、覆盆子提取物、龙眼肉提取物、黑枣提取物、黄精提取物、藿香提取物、桔梗提取物、莲子提取物、桑椹提取物、山楂提取物、桃仁提取物、杏仁提取物、益智仁提取物、郁李仁提取物、淡竹叶提取物、紫苏提取物和核桃提取物的所有提取物,混合后加入固型剂,搓丸,完成。
所述磨粉时控制温度为5-10℃。
所述固型剂为炼蜜。
所述固型剂是采用蜂蜜在90-100℃下熬制至冒泡粘稠状即可。
所述熬制时长为2-3min。
所述固型剂与所有提取物混合总重量的比为0.5-0.8:1。
一种促进脑和身高发育兼具抑制性早熟的制剂的应用,所述制剂在制备儿童、青少年制剂产品中的应用。
最后应说明的是:以上所述仅为本发明的优选实施例而已,并不用于限制本发明的保护范围。凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。
Claims (10)
1.一种促进脑和身高发育兼具抑制性早熟的制剂,其特征在于,所述制剂主要由以下质量份数的原料制备得到:
百合9-30份、薄荷4-25份、砂仁1-20份、酸枣仁4-25份、陈皮6-27份、覆盆子0.5-18份、龙眼肉3-22份、黑枣4-23份、黄精0.5-18份、藿香0.5-18份、桔梗9-30份、莲子5-26份、桑椹5-26份、山楂1-20份、桃仁0.6-16份、杏仁0.6-16份、益智仁4-25份、郁李仁4-23份、淡竹叶4-23份、紫苏2-21份、核桃8-28份。
2.根据权利要求1所述的一种促进脑和身高发育兼具抑制性早熟的制剂,其特征在于,所述制剂主要由以下质量份数的原料制备得到:
百合14-25份、薄荷9-20份、砂仁5-15份、酸枣仁9-20份、陈皮11-22份、覆盆子4-14份、龙眼肉7-17份、黑枣8-18份、黄精4-14份、藿香4-14份、桔梗14-25份、莲子10-21份、桑椹10-21份、山楂5-15份、桃仁1-11份、杏仁1-11份、益智仁9-20份、郁李仁8-18份、淡竹叶8-18份、紫苏6-16份、核桃13-24份。
3.根据权利要求2所述的一种促进脑和身高发育兼具抑制性早熟的制剂,其特征在于,所述制剂主要由以下质量份数的原料制备得到:
百合19份、薄荷14份、砂仁10份、酸枣仁14份、陈皮16份、覆盆子9份、龙眼肉12份、黑枣13份、黄精9份、藿香9份、桔梗19份、莲子15份、桑椹15份、山楂10份、桃仁6份、杏仁6份、益智仁14份、郁李仁13份、淡竹叶13份、紫苏11份、核桃18份。
4.一种如权利要求1-3任一项所述的促进脑和身高发育兼具抑制性早熟的制剂的制备方法,其特征在于,包括如下步骤:
选取百合、薄荷、砂仁、酸枣仁、陈皮、覆盆子、龙眼肉、黑枣、黄精、藿香、桔梗、莲子、桑椹、山楂、桃仁、杏仁、益智仁、郁李仁、淡竹叶、紫苏、核桃分别经干燥、磨粉后,水提分别获得提取物后;
按照相应质量份数选取百合提取物、薄荷提取物、砂仁提取物、酸枣仁提取物、陈皮提取物、覆盆子提取物、龙眼肉提取物、黑枣提取物、黄精提取物、藿香提取物、桔梗提取物、莲子提取物、桑椹提取物、山楂提取物、桃仁提取物、杏仁提取物、益智仁提取物、郁李仁提取物、淡竹叶提取物、紫苏提取物和核桃提取物的所有提取物,混合后加入固型剂,搓丸,完成。
5.根据权利要求4所述的一种促进脑和身高发育兼具抑制性早熟的制剂的制备方法,其特征在于,所述磨粉时控制温度为5-10℃。
6.根据权利要求4所述的一种促进脑和身高发育兼具抑制性早熟的制剂的制备方法,其特征在于,所述固型剂为炼蜜。
7.根据权利要求6所述的一种促进脑和身高发育兼具抑制性早熟的制剂的制备方法,其特征在于,所述固型剂是采用蜂蜜在90-100℃下熬制至冒泡粘稠状即可。
8.根据权利要求7所述的一种促进脑和身高发育兼具抑制性早熟的制剂的制备方法,其特征在于,所述熬制时长为2-3min。
9.根据权利要求4所述的一种促进脑和身高发育兼具抑制性早熟的制剂的制备方法,其特征在于,所述固型剂与所有提取物混合总重量的比为0.5-0.8:1。
10.一种如权利要求1-3任一项所述的促进脑和身高发育兼具抑制性早熟的制剂的应用,其特征在于,所述制剂在制备儿童、青少年制剂产品中的应用。
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