CN116941700A - Throat-clearing and throat-moistening candy rich in vitamin C and preparation method thereof - Google Patents
Throat-clearing and throat-moistening candy rich in vitamin C and preparation method thereof Download PDFInfo
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- CN116941700A CN116941700A CN202310956057.8A CN202310956057A CN116941700A CN 116941700 A CN116941700 A CN 116941700A CN 202310956057 A CN202310956057 A CN 202310956057A CN 116941700 A CN116941700 A CN 116941700A
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- Prior art keywords
- throat
- concentrated juice
- moistening
- clearing
- moistening candy
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title claims abstract description 64
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 title claims abstract description 29
- 229930003268 Vitamin C Natural products 0.000 title claims abstract description 29
- 239000011718 vitamin C Substances 0.000 title claims abstract description 29
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- 238000002360 preparation method Methods 0.000 title claims abstract description 17
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/40—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the fats used
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a throat-clearing and throat-moistening candy rich in vitamin C and a preparation method thereof, belonging to the technical field of foods. The invention takes mesona chinensis benth, liquorice, chrysanthemum, fructus momordicae, honeysuckle, platycodon grandiflorum, dried orange peel, dwarf lilyturf tuber, natural menthol and roxburgh rose concentrated juice as main materials, white granulated sugar, glucose syrup, maltodextrin, phospholipid and beeswax are added as auxiliary materials, citric acid monohydrate and citric acid concentrated juice are added to prepare the throat-clearing and throat-moistening candy, and the throat-moistening candy has moderate sweet taste, unique flavor of roxburgh rose, reliable throat-clearing and throat-moistening efficacy, high stability and long shelf life.
Description
Technical Field
The invention belongs to the technical field of foods, and particularly relates to a throat-clearing and throat-moistening candy rich in vitamin C and a preparation method thereof.
Background
In daily life, improper habits such as excessive throat use, stay up, eating spicy and irritating food, smoking alcoholism and the like, and long-term environments filled with chemical gas and dust can cause pharyngeal discomfort, and common symptoms are pharyngeal pain, dryness, foreign body sensation, pharyngeal itch and the like. Pharyngeal discomfort affects daily communication and even the quality of work and life, and therefore clearing the pharynx has become an urgent need for many people with pharyngeal discomfort. To alleviate pharyngeal discomfort, consumers often use throat-moistening products to alleviate. The throat-moistening candy in the current market is various in variety, is mostly prepared by adding one or more Chinese herbal medicines into sugar such as sucrose, maltose and the like, can relieve the discomfort of throat, and is convenient to eat. The food added with the Chinese herbal medicines has the advantages of high safety, obvious effect, suitability for long-term eating and the like, and is popular with consumers. Therefore, the product prepared by taking the Chinese herbal medicines as raw materials has outstanding effects and market advantages, and can fully meet the needs of consumers.
Chinese patent CN104664011A discloses a composition with throat-clearing and health-care functions and a preparation method thereof, wherein the composition is prepared from chrysanthemum, honeysuckle, platycodon grandiflorum, dark plum, fructus momordicae, liquorice, natural menthol, white granulated sugar, glucose syrup and maltodextrin, and has the throat-clearing and health-care functions.
Chinese patent CN103704450A discloses a throat-moistening candy and a preparation method thereof, the throat-moistening candy comprises isomaltulose alcohol, natural menthol, mesona chinensis, liquorice, chrysanthemum, fructus momordicae and honeysuckle, the obtained throat-moistening candy has good taste and high stability, has the effects of clearing heat, detoxicating and clearing throat, meets the requirements of most consumers, and is suitable for obesity and diabetes patients.
However, the existing throat-wetting products have various types, but have uneven quality, and have many defects in the aspects of single flavor and taste, poor storage stability and the like, and cannot meet the demands of consumers. There is therefore a need for improvements over existing throat-moistening products.
The roxburgh rose enjoys the reputation of 'the king of VC, the king of VP and the king of SOD' of three king, has higher nutritive value and unique flavor, and can be used in throat-moistening products. However, the current Rosa roxburghii products mainly comprise common foods such as beverages, preserved fruits and the like, the added value is low, the Rosa roxburghii is extremely sour and astringent, and the taste of the foods can be influenced when the Rosa roxburghii products are added into the foods, so that the market of the Rosa roxburghii is limited. Chinese patent CN107467338A discloses a throat-moistening candy and a preparation method thereof, wherein the throat-moistening candy comprises fructus Rosae Normalis, rhizoma polygonati officinalis, mulberry, fresh cogongrass rhizome, gardenia, lotus leaf, honeysuckle and chrysanthemum, and has the effects of clearing heat from throat and benefiting throat. However, the throat-moistening candy needs to be boiled at high temperature in the preparation process, the vitamin C content is reduced due to long-time heating of the components such as the roxburgh rose, and the formability and the stability of the throat-moistening candy are affected. Therefore, in order to expand the market of Rosa roxburghii, it is necessary to improve the existing throat-wetting products.
Disclosure of Invention
The invention aims at overcoming the defects of the prior art and provides a throat-clearing and throat-moistening candy rich in vitamin C and a preparation method thereof. The preparation method is simple, and the obtained throat-clearing and throat-moistening candy is sweet and moderate in taste, has the unique flavor of the roxburgh rose, and is reliable in throat-clearing and throat-moistening effects and high in storage stability.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows:
a throat-clearing and throat-moistening candy rich in vitamin C comprises throat-moistening candy concentrated juice, adjuvants, menthol, fructus Rosae Normalis concentrated juice, citric acid monohydrate, citric acid concentrated juice and adjuvants; wherein,,
the raw materials in the throat-moistening candy concentrated juice comprise mesona chinensis benth, liquorice, chrysanthemum, fructus momordicae, honeysuckle, platycodon grandiflorum, dried orange peel and dwarf lilyturf tuber;
the auxiliary materials comprise white granulated sugar, glucose syrup, phospholipid and beeswax.
Further, the vitamin C-enriched throat-clearing and moistening candy comprises the following components in parts by weight: 2-7 parts of throat-moistening candy concentrated juice, 0.3-0.6 part of natural menthol, 4-7 parts of roxburgh rose concentrated juice, 1-2 parts of citric acid monohydrate, 0.5-1 part of citric acid concentrated juice and 100-300 parts of auxiliary materials; the throat-moistening candy concentrated juice comprises 50-55% of mesona chinensis benth, 20-25% of liquorice, 10-15% of chrysanthemum, 5-10% of fructus momordicae, 1-5% of honeysuckle, 2-4% of platycodon grandiflorum, 1-2% of dried orange peel and 1-3% of dwarf lilyturf tuber by weight.
Further, the vitamin C-enriched throat-clearing and moistening candy comprises the following components in parts by weight: 3-4 parts of throat-moistening candy concentrated juice, 0.3-0.4 part of natural menthol, 4-5.5 parts of roxburgh rose concentrated juice, 1-1.5 parts of citric acid monohydrate, 0.7-1 part of citric acid concentrated juice and 200-300 parts of auxiliary materials; the throat-moistening candy concentrated juice comprises 52-53% of mesona chinensis, 20-21% of liquorice, 12-13% of chrysanthemum, 8-9% of fructus momordicae, 2-3% of honeysuckle, 2-3% of platycodon grandiflorum, 1-1.5% of dried orange peel and 1-2% of dwarf lilyturf tuber by weight.
Preferably, the vitamin C-enriched throat-clearing and moistening candy comprises the following components in parts by weight: 3.5 parts of throat-moistening candy concentrated juice, 0.3 part of natural menthol, 4.1 parts of roxburgh rose concentrated juice, 1.25 parts of citric acid monohydrate, 0.9 part of citric acid concentrated juice and 240 parts of auxiliary materials; the throat-moistening candy concentrated juice comprises 53% of mesona chinensis benth, 21% of liquorice, 12% of chrysanthemum, 8% of fructus momordicae, 2% of honeysuckle, 2% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber by weight.
Further, the mass ratio of the dried orange peel to the dwarf lilyturf tuber to the platycodon root is 1:1-1.5:1-2.
Preferably, the mass ratio of the dried orange peel to the dwarf lilyturf tuber to the platycodon root is 1:1:2.
Further, the mass ratio of the white granulated sugar, the glucose syrup, the phospholipid and the beeswax in the auxiliary materials is 10:20-30:0.4-1:0.1-0.2.
Preferably, the mass ratio of the white granulated sugar, the glucose syrup, the phospholipid and the beeswax in the auxiliary materials is 10:24:0.6:0.15.
The invention also provides a preparation method of the throat-clearing and throat-moistening candy rich in vitamin C, which comprises the following steps:
(1) Extracting herba Mesonae chinensis, glycyrrhrizae radix, flos Chrysanthemi, fructus Siraitiae Grosvenorii, flos Lonicerae, radix Platycodi, pericarpium Citri Tangerinae and radix Ophiopogonis with water twice, precipitating with ethanol, and concentrating to obtain throat moistening sugar concentrated juice;
(2) Dissolving the auxiliary materials in water, decocting in vacuum, adding natural menthol, fructus Rosae Normalis concentrated juice, citric acid monohydrate, citric acid concentrated juice and the throat-moistening sugar concentrated juice obtained in the step (1), mixing uniformly to obtain concentrated sugar solution, and finally molding.
Further, in the step (1), the water extraction step is as follows: extracting herba Mesonae chinensis, glycyrrhrizae radix, flos Chrysanthemi, fructus Siraitiae Grosvenorii, flos Lonicerae, radix Platycodi, pericarpium Citri Tangerinae and radix Ophiopogonis with 6-8 times of water for 2-3 times, mixing the mixed solution, filtering, concentrating to obtain concentrated solution with Baume degree of 11-13Be at 70-90deg.C.
Preferably, in the step (1), the water extraction step is as follows: extracting herba Mesonae chinensis, glycyrrhrizae radix, flos Chrysanthemi, fructus Siraitiae Grosvenorii, flos Lonicerae, radix Platycodi, pericarpium Citri Tangerinae and radix Ophiopogonis with water twice, the first time with 7-8 times of hot water at 80-90deg.C for 1-2 hr, the second time with 5-6 times of water at 40-50deg.C for 0.5-1 hr, mixing the two extractive solutions, filtering, and concentrating to obtain concentrated solution with Baume degree of 12Be at 80deg.C.
Further, in the step (1), the alcohol precipitation step is as follows: adding 93-95% ethanol solution into the concentrated solution for ethanol precipitation to make the ethanol content in the concentrated solution Be 63-75%, standing for 24-36h, collecting supernatant, recovering ethanol, concentrating to obtain throat-moistening sugar concentrated juice, and making Baume degree Be 37-39Be at 65-75deg.C.
Preferably, in the step (1), the alcohol precipitation step is: adding 95% ethanol solution into the concentrated solution for ethanol precipitation to make the ethanol content in the concentrated solution Be 63%, standing for 30h, collecting supernatant, recovering ethanol, concentrating to obtain throat-moistening candy concentrated juice, wherein the Baume degree is 38Be at 70deg.C.
Further, in the step (2), the mass ratio of the auxiliary materials to the water is 1:0.5-2; preferably, the mass ratio of the auxiliary materials to the water is 1:1.
Further, in the step (2), the dissolution temperature is 90-100 ℃; preferably, the dissolution temperature is 100 ℃.
Further, in the step (2), the vacuum boiling temperature is 135-150 ℃; preferably, the vacuum cooking temperature is 140 ℃.
Further, in the step (2), the adding step of the roxburgh rose juice concentrate comprises the following steps: 30-50% of the total mass of the roxburgh rose concentrated juice is added, and the rest roxburgh rose concentrated juice is added after uniform mixing.
Further, in the step (2), the molding mode is bar molding or casting molding, preferably bar molding.
Compared with the prior art, the invention has the following beneficial effects:
(1) The invention takes the mesona chinensis benth, the chrysanthemum, the honeysuckle and the like as main materials to prepare the throat-clearing and throat-moistening candy, the preparation method is simple, the obtained throat-moistening candy has moderate sweet taste, has the unique flavor of the roxburgh rose, and has reliable throat-clearing and throat-moistening effects and high storage stability;
(2) The invention is beneficial to improving the sensory quality of the throat-clearing and throat-moistening candy and improving the throat-clearing effect by regulating and controlling the content of each component;
(3) The roxburgh rose juice concentrate is added into the throat-moistening candy, so that the throat-moistening candy is rich in vitamin C and has the unique flavor of roxburgh rose; compared with the addition of the roxburgh rose fruit powder, the roxburgh rose fruit is selected to be added in the form of pear concentrated juice, so that the formability and the storage stability of the throat-moistening candy can be improved; the roxburgh rose juice and the throat-moistening sugar juice are added after being boiled in vacuum in sugar liquid, the roxburgh rose juice and the throat-moistening sugar juice are used as acidic substances, the reducing sugar conversion of white granulated sugar can be increased through high temperature in an acidic environment, the reducing sugar is too high, the melting of sugar and the change of water are easily caused, the deformation of a product is caused, and the quality of the product is influenced, so that the roxburgh rose juice and the throat-moistening sugar juice are added after being boiled, high-temperature treatment is avoided, and the formability and the storage stability of the throat-moistening sugar can be improved;
(4) The platycodon grandiflorum, the dried orange peel and the dwarf lilyturf tuber have certain cooperative use, are beneficial to increasing the throat clearing efficacy of the throat-moistening candy, improving the storage stability and prolonging the shelf life;
(5) The phospholipid and the beeswax are added into the auxiliary materials, so that the formability of the phospholipid and the beeswax is improved, and the yield of finished products is increased; the proportion of auxiliary materials is controlled, so that the stability of the throat-moistening candy is further improved, the throat-moistening candy is not deformed in the storage process, and the storage time is long.
Drawings
FIG. 1 is a flow chart of the method for preparing the throat-clearing and moistening candy of the embodiment 1;
FIG. 2 is a flow chart of the method for preparing the throat-moistening candy concentrated juice of the invention in example 1.
Detailed Description
The following non-limiting examples will enable those of ordinary skill in the art to more fully understand the invention and are not intended to limit the invention in any way. The following is merely exemplary of the scope of the invention as claimed and many variations and modifications of the invention will be apparent to those skilled in the art in light of the disclosure, which are intended to be within the scope of the invention as claimed.
The invention is further illustrated by means of the following specific examples. The various chemical reagents used in the examples of the present invention were obtained by conventional commercial means unless otherwise specified.
Example 1
A vitamin C-rich throat-clearing and moistening candy comprising: 3.5 parts of throat-moistening candy concentrated juice, 0.3 part of natural menthol, 4.1 parts of roxburgh rose concentrated juice, 1.25 parts of citric acid monohydrate, 0.9 part of citric acid concentrated juice and 240 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 53% of mesona chinensis benth, 21% of liquorice, 12% of chrysanthemum, 8% of fructus momordicae, 2% of honeysuckle, 2% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber by weight.
The auxiliary materials comprise white granulated sugar, glucose syrup, phospholipid and beeswax in a mass ratio of 10:24:0.6:0.15.
The embodiment also provides a preparation method of the vitamin C-enriched throat-clearing and moistening candy (the flow chart is shown in figure 1), which comprises the following steps:
(1) Weighing herba Mesonae chinensis, glycyrrhrizae radix, flos Chrysanthemi, fructus Siraitiae Grosvenorii, flos Lonicerae, radix Platycodi, pericarpium Citri Tangerinae and radix Ophiopogonis according to formula, extracting with water twice, firstly with 8 times of hot water at 90deg.C for 1 hr, secondly with 6 times of water at 50deg.C for 0.5 hr, mixing the two extractive solutions, filtering, concentrating to Baume degree of 12Be (80deg.C), and collecting concentrated solution; adding 95% ethanol into the concentrated solution for ethanol precipitation to make the ethanol content of the concentrated solution 63%, standing for 30h, collecting supernatant, recovering ethanol, concentrating to Baume degree of 38Be (70deg.C) to obtain throat-moistening sugar concentrated juice (the preparation method of throat-moistening sugar concentrated juice is shown in figure 2); the yield is 28%;
(2) Mixing the auxiliary materials with purified water according to the same mass, stirring and dissolving the mixture slightly at 100 ℃ to obtain an initial sugar solution, boiling the initial sugar solution in vacuum at 140 ℃ to obtain a concentrated sugar solution, adding 40% of the total mass of the throat-moistening sugar concentrated juice, the natural menthol and the roxburgh rose concentrated juice in the step (1), citric acid monohydrate and citric acid concentrated juice, uniformly mixing the materials, adding the rest roxburgh rose concentrated juice, finally bracing and forming the mixture to obtain the throat-moistening sugar, and packaging the throat-moistening sugar according to the specification of 2.8 g/granule and 10 granule/bag.
Example 2
The difference from example 1 is that the vitamin C-enriched throat-clearing and moistening candy comprises:
2 parts of throat-moistening candy concentrated juice, 0.6 part of natural menthol, 7 parts of roxburgh rose concentrated juice, 2 parts of citric acid monohydrate, 1 part of citric acid concentrated juice and 180 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 50% of mesona chinensis benth, 25% of liquorice, 10% of chrysanthemum, 10% of momordica grosvenori, 1% of honeysuckle, 2% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber by weight;
the auxiliary materials are white granulated sugar, glucose syrup, phospholipid and beeswax in a ratio of 10:20:0.4:0.1.
Example 3
The difference from example 1 is that the vitamin C-enriched throat-clearing and moistening candy comprises:
3 parts of throat-moistening candy concentrated juice, 0.4 part of natural menthol, 5.5 parts of roxburgh rose concentrated juice, 1.5 parts of citric acid monohydrate, 1 part of citric acid concentrated juice and 270 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises, by weight, 52% of mesona chinensis benth, 20% of liquorice, 12% of chrysanthemum, 8% of fructus momordicae, 2% of honeysuckle, 2.5% of platycodon grandiflorum, 1.5% of dried orange peel and 2% of radix ophiopogonis;
the auxiliary materials are white granulated sugar, glucose syrup, phospholipid and beeswax in a ratio of 10:30:1:0.2.
Example 4
The difference from example 1 is that the vitamin C-enriched throat-clearing and moistening candy comprises:
4 parts of throat-moistening candy concentrated juice, 0.3-part of natural menthol, 4 parts of roxburgh rose concentrated juice, 1 part of citric acid monohydrate, 0.7 part of citric acid concentrated juice and 200 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 53% of mesona chinensis benth, 21% of liquorice, 12% of chrysanthemum, 8% of fructus momordicae, 2% of honeysuckle, 2% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber by weight;
the auxiliary materials are white granulated sugar, glucose syrup, phospholipid and beeswax in a ratio of 10:24:0.6:0.15.
Example 5
The difference from example 1 is that the vitamin C-enriched throat-clearing and moistening candy comprises:
7 parts of throat-moistening candy concentrated juice, 0.3 part of natural menthol, 4 parts of roxburgh rose concentrated juice, 1 part of citric acid monohydrate, 0.5 part of citric acid concentrated juice and 280 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 55% of mesona chinensis benth, 25% of liquorice, 10% of chrysanthemum, 5% of momordica grosvenori, 1% of honeysuckle, 2% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber by weight;
the auxiliary materials are white granulated sugar, glucose syrup, phospholipid and beeswax in a ratio of 10:24:0.6:0.15.
Comparative example 1
The difference from example 1 is that the vitamin C-enriched throat-clearing and moistening candy comprises:
1 part of throat-moistening candy concentrated juice, 0.7 part of natural menthol, 8 parts of roxburgh rose concentrated juice, 3 parts of citric acid monohydrate, 0.5 part of citric acid concentrated juice and 280 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 58% of mesona chinensis benth, 15% of liquorice, 5% of chrysanthemum, 12% of momordica grosvenori, 6% of honeysuckle, 2% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber by weight;
the auxiliary materials are white granulated sugar, glucose syrup, phospholipid and beeswax in a ratio of 10:24:0.6:0.15.
Comparative example 2
The difference from example 1 is that the vitamin C-enriched throat-clearing and moistening candy comprises:
8 parts of throat-moistening candy concentrated juice, 0.1 part of natural menthol, 2 parts of roxburgh rose concentrated juice, 0.5 part of citric acid monohydrate, 0.5 part of citric acid concentrated juice and 280 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises, by weight, 45% of mesona chinensis benth, 30% of liquorice, 18% of chrysanthemum, 3% of momordica grosvenori, 1% of honeysuckle, 1% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber;
the auxiliary materials are white granulated sugar, glucose syrup, phospholipid and beeswax in a ratio of 10:24:0.6:0.15.
Comparative example 3
The difference with the example 1 is that the mass ratio of the dried orange peel, the dwarf lilyturf tuber and the platycodon root is 1:0.5:0.5; the total amount of the dried orange peel, the dwarf lilyturf tuber and the platycodon root in the throat-moistening candy concentrated juice is unchanged.
Comparative example 4
The difference with the example 1 is that the mass ratio of the dried orange peel, the dwarf lilyturf tuber and the platycodon root is 1:2:3; the total amount of the dried orange peel, the dwarf lilyturf tuber and the platycodon root in the throat-moistening candy concentrated juice is unchanged.
Comparative example 5
The difference from example 1 is that the orange peel is replaced by an equal amount of exocarpium Citri rubrum.
Comparative example 6
The difference from example 1 is that the same amount of radix asparagi is used instead of radix Ophiopogonis.
Comparative example 7
The difference from example 1 is that the auxiliary materials comprise white granulated sugar, glucose syrup, phospholipid and beeswax in a mass ratio of 10:24:2:0.3.
Comparative example 8
The difference from example 1 is that the auxiliary materials comprise white granulated sugar, glucose syrup, phospholipid and beeswax with the mass ratio of 10:24:0.2:0.05.
Comparative example 9
The difference from example 1 is that no beeswax is added to the adjuvant.
Comparative example 10
The difference from example 1 is that no phospholipid is added to the adjuvant.
Comparative example 11
The difference from example 1 is that the roxburgh rose fruit powder is used in place of the roxburgh rose juice concentrate in equal amounts.
Comparative example 12
The difference from example 1 is that the concentrated juice of Rosa roxburghii is added before the sugar is boiled in vacuum.
Comparative example 13
The difference from example 1 is that in the water extraction process of mesona chinensis benth, liquorice, chrysanthemum, fructus momordicae, honeysuckle, platycodon grandiflorum, dried orange peel and dwarf lilyturf tuber, the water temperature used in the two water extraction processes is 50 ℃. The yield of the throat-moistening candy concentrated juice is 20.8%.
Comparative example 14
The difference from example 1 is that in the process of preparing the throat-moistening candy concentrated juice, the centrifugation method is used for purifying and separating instead of alcohol precipitation, and the rotation speed of centrifugation is 1000r/min and the time is 20min. The yield of the throat-moistening candy concentrated juice is 18.2%.
Experimental example 1
The yield of the finished product was calculated from the ratio of the actual yield (pellet) to the theoretical yield (pellet) of the throat-clearing and throat-moistening saccharides of examples 1 to 5 and comparative examples 1 to 14, and the results are shown in Table 1 below.
TABLE 1 yield of finished products
| Group of | Yield of finished product | Group of | Yield of finished product |
| Example 1 | 86.69 | Comparative example 6 | 85.11 |
| Example 2 | 86.16 | Comparative example 7 | 85.15 |
| Example 3 | 84.84 | Comparative example 8 | 82.22 |
| Example 4 | 84.37 | Comparative example 9 | 67.22 |
| Example 5 | 86.02 | Comparative example 10 | 65.71 |
| Comparative example 1 | 83.74 | Comparative example 11 | 76.57 |
| Comparative example 2 | 84.05 | Comparative example 12 | 78.22 |
| Comparative example 3 | 85.51 | Comparative example 13 | 80.15 |
| Comparative example 4 | 84.40 | Comparative example 14 | 80.03 |
| Comparative example 5 | 84.37 | —— | —— |
The results show that the finished product yield of the throat-clearing and wetting sugar obtained in the examples 1-5 is higher than 84%, and the finished product yield is high and the formability is good; the yield of the finished products of the throat-clearing and throat-moistening sugar obtained in the comparative examples 9 and 10 is lower than that of the finished products of the throat-clearing and throat-moistening sugar obtained in the example 1, and the forming property can be improved by adding phospholipid and beeswax into auxiliary materials; the yield of the finished products of the throat-clearing and throat-moistening sugar obtained in the comparative examples 11 and 12 is lower than that of the example 1, and compared with the roxburgh rose fruit powder, the throat-clearing and throat-moistening sugar is added in the form of roxburgh rose juice concentrate, and the addition of the roxburgh rose juice concentrate after sugar boiling is controlled, so that the influence of high temperature is avoided, and the formability is improved; the yield of the finished products of the throat-clearing and throat-moistening sugar obtained in the comparative examples 13 and 14 is lower than that of the finished products of the example 1, and the conditions of extraction, purification and separation in the preparation process of the throat-moistening sugar concentrated juice can be seen to influence the formability of the products.
Experimental example 2
Product quality
The sensory index, physicochemical property and microorganism index of the throat-moistening candy were measured by referring to the method described in Q/WLJ0003S-2019 using the throat-clearing throat-moistening candy obtained in examples 1-5 and comparative examples 1-14 as samples, the evaluation criteria are shown in Table 2 below, and the results are shown in Table 3.
TABLE 2 evaluation criteria
TABLE 3 physicochemical Properties and marking composition test results
The results show that the throat-clearing and throat-wetting sugar meets the regulations on sensory indexes, physicochemical properties and marking components, and the total colony content in the throat-clearing and throat-wetting sugar is less than 10CFU/g, the coliform group content is less than 30MPN/100g, the mould is less than 10CFU/g and the yeast is less than 10CFU/g in terms of microbial indexes, thereby meeting the regulations. Compared with the throat-moistening sugar obtained in the comparative examples 11 and 12, the L (+) -ascorbic acid content is lower than that of the examples, and compared with the throat-moistening sugar added in the form of roxburgh rose fruit powder or the roxburgh rose juice concentrate before sugar boiling, the throat-moistening sugar disclosed by the invention is added in the form of the roxburgh rose juice concentrate after sugar boiling, so that the loss of L (+) -ascorbic acid in the processing process can be reduced, and the quality of products can be improved; the content of L- (+) -ascorbic acid and chlorogenic acid which are the marking components of the throat-moistening sugar obtained in comparative examples 13 and 14 are lower than those of the examples, and the conditions of extraction, separation and purification in the preparation process of the throat-moistening sugar concentrated juice can influence the product quality of the throat-moistening sugar.
Experimental example 3
Animal experiment with throat clearing function
1 material:
1.1 sample: the throat drops obtained in the embodiment 1 and the comparative examples 1 to 4 of the present invention were used as samples, the recommended oral dosage for human body was 12 grains/day, and the dosage of the samples was 0.56/kg.bw calculated according to the weight of 60kg of an adult.
1.2 experimental animals: SPF-grade SD male rats weighing 150-220g, purchased from Peking Vietnam De Liwa laboratory animal research center.
1.3 experimental grouping and sample administration: male rats were randomly divided into 7 experimental groups and 1 blank control group, 10 experimental groups were administered with test substances at a dose of 5.6 g/kg.bw (equivalent to 10 times the recommended dose for human body), and the gavage volume was 1.0mL/100 g.bw, and the control group was administered with equal volume of distilled water for 30 consecutive days.
2 Experimental methods
2.1 rat Cotton ball implantation experiments
The autoclaved cotton balls were implanted at the groin on both sides of the rats 8 days before the end of the experiment, with a mass of about 22mg, and then the subjects were continued to be administered. On the day of the end of the experiment, after 1h of the test, the rats were sacrificed, the cotton bud tissue was removed, weighed, dried at 60 ℃ for 1 hour and then weighed again, and the net granuloma amount was calculated.
Net granuloma (mg) =dry cotton granuloma weight after drying-raw cotton weight
2.2 rat toe swelling experiment
On the day of the end of the experiment, after 1h of the test, the volume of the hind limb toe of the rat was measured and recorded as the initial toe volume, then 4 ten thousand 0.1mL of dextran with the concentration of 1% was injected under the skin of the hind limb toe of the rat, the toe volumes of the rat were measured after 1, 2, 4 and 6 hours respectively, the difference between the toe volumes of the rat measured at different times and the toe volume before the action of the inflammatory agent was taken as the swelling value, and the toe swelling rate was calculated by the following calculation formula:
toe swelling ratio (%) =swelling value/pre-inflammatory toe volume×100%.
3 results
Statistical analysis was performed using Spss software and the results are shown in tables 4-5 below.
TABLE 4 influence of throat-clearing and throat-wetting sugar on rat and mouse body weight
The results show that in the experiments of cotton ball implantation and ear swelling of rats, the weight of each group of rats is increased, and no obvious difference exists among the groups, which indicates that the tested drugs have no obvious toxic or side effect.
TABLE 5 Experimental results of rat cotton ball implantation and toe swelling
Note that: compared with blank group, p is less than 0.05
The results show that in the rat cotton ball implantation experiment, the granuloma net amount corresponding to the example 1 and the comparative example is obviously reduced compared with the blank control, and the granuloma net amount corresponding to the comparative example is obviously higher than that of the example 1; in toe swelling experiments, the toe swelling rate of rats was significantly reduced at 4h and 6h after inflammation, and there was a significant difference compared with the blank control group. Therefore, the throat-moistening candy provided by the invention is administrated to rats by oral gavage for 30 days at a dosage of 5.6 g/kg.bw, has the effect of intervening acute and chronic inflammation on animals, namely has the function of clearing throat on animals, controls the types and the proportions of all components, and is beneficial to improving the throat-clearing function of the throat-moistening candy.
Experimental example 4
Human body test feeding experiment with throat clearing function
1 subject:
patients with acute and chronic pharyngitis and throat discomfort, which are aged 17-56 and have no major viscera diseases such as barycenter, liver, kidney, etc., are selected as 106 subjects, and subjective symptoms of the subjects include pharyngalgia, itching throat, dry throat, foreign body sensation, phlegm distress, etc., and are scored according to the symptom degree (1-10 points). At least one of pharyngeal mucosal edema, mucosal congestion, pharyngeal wall lymphoproliferation and secretion attachment is examined. Of these, 55 men and 51 women.
2 groups of experiments and administration of samples to be tested
Subjects were randomized into 2 groups of 53 per group by symptom. Wherein the control group takes the throat tablet of the throat according to the instruction, 1 tablet each time is taken 2 times per day; the experiment group takes the throat-clearing and wetting candy of the invention, and 1 tablet is taken twice a day.
2 efficacy criterion: reference is made to the guidelines for clinical study of new Chinese medicine issued by the Ministry of health.
The effect is shown: the symptoms are relieved or disappeared, the pharyngeal signs are relieved by 2 grades, and the single scoring of the symptoms is reduced by more than or equal to 4 grades;
the method is effective: symptoms are relieved, pharyngeal signs are relieved by 1-2 grades, and single-item scores of symptoms are reduced by 2-3 grades;
invalidation: symptoms and signs are unchanged, and single scoring of the symptoms is reduced by less than 2.
3 results of experiments
The results of the overall effect evaluation and symptom improvement are shown in tables 6 to 7 below.
TABLE 6 evaluation results of overall effects
| Group of | Example number (example) | Display effect (example) | Effective (example) | Invalidation (example) | Total effective rate (example) |
| Control group | 53 | 13 | 30 | 10 | 81.13 |
| Experimental group | 53 | 23 | 28 | 2 | 96.22** |
Note that: p < 0.01 compared to control group
TABLE 7 symptomatic improvement Condition
Note that: p < 0.05, p < 0.01 compared to control group
The results show that the throat-moistening throat sugar provided by the invention can improve the discomfort condition of throat, has obvious improvement effects on symptoms such as pharyngalgia, itching throat, dry throat, foreign body sensation, phlegm and the like, and especially has obvious improvement effects on the itching throat, foreign body sensation and phlegm and the like, and the effective rate is more than 90%.
Experimental example 5
Stability test:
the throat drops obtained in examples 1 to 5 and comparative examples 1 to 14 were accelerated for 1, 2, 3 and 6 months in an environment with a temperature of 40℃and a relative humidity of 75%, and were sampled and compared after the completion of the experiment, and the results are shown in tables 8 to 9 below.
TABLE 8 marker components
The results show that after the throat-clearing and throat-moistening candy obtained in the example 1 is accelerated to be examined for 1-6 months in an environment with the temperature of 40 ℃ and the relative humidity of 75%, the contents of L- (+) -ascorbic acid and chlorogenic acid are not obviously reduced, which indicates that the stability is good and the storage time is long; the throat-clearing and throat-moistening candy of comparative examples 3-12 starts to decrease in content of L- (+) -ascorbic acid and chlorogenic acid after accelerated examination for 3 qualified months, and has a remarkable difference from example 1 after 6 months. Therefore, the tangerine peel, the dwarf lilyturf tuber and the platycodon root have a certain synergistic effect, which is beneficial to improving the storage stability of the throat-moistening candy, so that the L- (+) -ascorbic acid content and the chlorogenic acid content of the throat-moistening candy cannot be obviously reduced in the long-term storage process, and the shelf life of the throat-moistening candy is prolonged; in addition, the addition modes and the sequence of the specific auxiliary material components and the specific auxiliary material proportions are favorable for improving the stability of the product.
TABLE 9 physicochemical Properties
As a result, in the accelerated investigation process of 6 months, the variation amplitude of the total sugar content, the reducing sugar content and the moisture content of the throat-moistening sugar of comparative examples 9-12 is obviously higher than that of example 1, and the selection of specific auxiliary material proportion and the addition mode and sequence of the roxburgh rose are beneficial to improving the storage stability of the throat-moistening sugar and prolonging the shelf life.
In addition, experiments show that the throat drops of examples 1-5 and comparative examples 1-14 have no obvious change in microbial indexes in the accelerated investigation process of 6 months, the total colony content is less than 10CFU/g, the coliform group content is less than 30MPN/100g, the mould is less than 10CFU/g, and the yeast is less than 10CFU/g, so that the requirements are met; in terms of sensory indexes, the throat-moistening sugar of examples 1-5 is not deformed and adhered in the accelerated investigation process of 6 months, while the throat-moistening sugar obtained in comparative examples 11 and 12 is deformed and adhered, and the fact that the addition of the roxburgh rose juice concentrate before sugar boiling can lead to the product quality of the throat-moistening sugar caused by overhigh reducing sugar in a high-temperature state of later sugar liquid boiling, so that the throat-moistening sugar is easy to deform in the storage process, and the addition of the roxburgh rose juice concentrate after boiling can avoid the product deformation in the storage process of the throat-moistening sugar, so that the stability is improved; the throat-moistening sugar obtained in the comparative examples 7 and 8 is adhered, which shows that the throat-moistening sugar product is not deformed in the storage process by selecting the auxiliary materials with specific proportions.
The previous description of the embodiments is provided to facilitate a person of ordinary skill in the art in order to make and use the present invention. It will be apparent to those skilled in the art that various modifications can be readily made to these embodiments and the generic principles described herein may be applied to other embodiments without the use of the inventive faculty. Therefore, the present invention is not limited to the above-described embodiments, and those skilled in the art, based on the present disclosure, should make improvements and modifications without departing from the scope of the present invention.
Claims (15)
1. A throat-clearing and throat-moistening candy rich in vitamin C is characterized by comprising throat-moistening candy concentrated juice, auxiliary materials, menthol, roxburgh rose concentrated juice, citric acid monohydrate, citric acid concentrated juice and auxiliary materials; wherein,,
the raw materials in the throat-moistening candy concentrated juice comprise mesona chinensis benth, liquorice, chrysanthemum, fructus momordicae, honeysuckle, platycodon grandiflorum, dried orange peel and dwarf lilyturf tuber;
the auxiliary materials comprise white granulated sugar, glucose syrup, phospholipid and beeswax.
2. The vitamin C enriched throat-clearing and moistening candy of claim 1, comprising, in parts by weight: 2-7 parts of throat-moistening candy concentrated juice, 0.3-0.6 part of natural menthol, 4-7 parts of roxburgh rose concentrated juice, 1-2 parts of citric acid monohydrate, 0.5-1 part of citric acid concentrated juice and 100-300 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 50-55% of mesona chinensis benth, 20-25% of liquorice, 10-15% of chrysanthemum, 5-10% of fructus momordicae, 1-5% of honeysuckle, 2-4% of platycodon grandiflorum, 1-2% of dried orange peel and 1-3% of dwarf lilyturf tuber by weight.
3. The vitamin C enriched throat-clearing and moistening candy of claim 2, comprising, in parts by weight: 3-4 parts of throat-moistening candy concentrated juice, 0.3-0.4 part of natural menthol, 4-5.5 parts of roxburgh rose concentrated juice, 1-1.5 parts of citric acid monohydrate, 0.7-1 part of citric acid concentrated juice and 200-300 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 52-53% of mesona chinensis benth, 20-21% of liquorice, 12-13% of chrysanthemum, 8-9% of fructus momordicae, 2-3% of honeysuckle, 2-3% of platycodon grandiflorum, 1-1.5% of dried orange peel and 1-2% of dwarf lilyturf tuber by weight.
4. The vitamin C enriched throat-clearing and moistening candy of claim 3, comprising, in parts by weight: 3.5 parts of throat-moistening candy concentrated juice, 0.3 part of natural menthol, 4.1 parts of roxburgh rose concentrated juice, 1.25 parts of citric acid monohydrate, 0.9 part of citric acid concentrated juice and 240 parts of auxiliary materials;
the throat-moistening candy concentrated juice comprises 53% of mesona chinensis benth, 21% of liquorice, 12% of chrysanthemum, 8% of fructus momordicae, 2% of honeysuckle, 2% of platycodon grandiflorum, 1% of dried orange peel and 1% of dwarf lilyturf tuber by weight.
5. The vitamin C-enriched throat-clearing and moistening candy according to claim 1, wherein the mass ratio of the dried orange peel, the dwarf lilyturf tuber and the platycodon root is 1:1-1.5:1-2.
6. The vitamin C-enriched throat-clearing and moistening candy of claim 5, wherein the mass ratio of the dried orange peel, the dwarf lilyturf tuber and the platycodon root is 1:1:2.
7. The vitamin C-enriched throat-clearing and moistening candy according to claim 1, wherein the mass ratio of the white granulated sugar, glucose syrup, phospholipid and beeswax in the auxiliary materials is 10:20-30:0.4-1:0.1-0.2.
8. The vitamin C-enriched throat-clearing and moistening candy according to claim 7, wherein the mass ratio of white granulated sugar, glucose syrup, phospholipids and beeswax in the auxiliary material is 10:24:0.6:0.15.
9. A process for the preparation of a vitamin C enriched throat drop as claimed in any one of claims 1 to 8 comprising the steps of:
(1) Extracting herba Mesonae chinensis, glycyrrhrizae radix, flos Chrysanthemi, fructus Siraitiae Grosvenorii, flos Lonicerae, radix Platycodi, pericarpium Citri Tangerinae and radix Ophiopogonis with water twice, precipitating with ethanol, and concentrating to obtain throat moistening sugar concentrated juice;
(2) Dissolving the auxiliary materials in water, decocting in vacuum, adding natural menthol, fructus Rosae Normalis concentrated juice, citric acid monohydrate, citric acid concentrated juice and the throat-moistening sugar concentrated juice obtained in the step (1), mixing uniformly to obtain concentrated sugar solution, and finally molding.
10. The method of claim 9, wherein the water extraction step is: extracting herba Mesonae chinensis, glycyrrhrizae radix, flos Chrysanthemi, fructus Siraitiae Grosvenorii, flos Lonicerae, radix Platycodi, pericarpium Citri Tangerinae and radix Ophiopogonis with 6-8 times of water for 2-3 times, mixing the mixed solution, filtering, concentrating to obtain concentrated solution with Baume degree of 11-13Be at 70-90deg.C.
11. The method of claim 10, wherein the water extraction step is: extracting herba Mesonae chinensis, glycyrrhrizae radix, flos Chrysanthemi, fructus Siraitiae Grosvenorii, flos Lonicerae, radix Platycodi, pericarpium Citri Tangerinae and radix Ophiopogonis with water twice, the first time with 7-8 times of hot water at 80-90deg.C for 1-2 hr, the second time with 5-6 times of water at 40-50deg.C for 0.5-1 hr, mixing the two extractive solutions, filtering, and concentrating to obtain concentrated solution with Baume degree of 12-13Be at 80deg.C.
12. The method of claim 9, wherein the alcohol precipitation step is: ethanol with the mass fraction of 93-95% is added into the concentrated solution for ethanol precipitation, the ethanol content in the concentrated solution is 63-75%, the concentrated solution is kept stand for 24-36h, the supernatant is taken for recovering ethanol, and the concentrated solution of the throat-moistening candy is obtained after concentration, and the Baume degree is 37-39Be at 65-75 ℃.
13. The method of claim 12, wherein the alcohol precipitation step is: adding 95% ethanol into the concentrated solution for ethanol precipitation to make the ethanol content in the concentrated solution Be 63%, standing for 30h, collecting supernatant, recovering ethanol, concentrating to obtain throat-moistening candy concentrated juice, wherein the Baume degree is 38Be at 70deg.C.
14. The method of claim 9, wherein in step (2), the step of adding the concentrated juice of the rosa roxburghii is: 30-50% of the total mass of the roxburgh rose concentrated juice is added, and the rest roxburgh rose concentrated juice is added after uniform mixing.
15. The method of claim 9, wherein the molding is bar molding or cast molding.
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