CN116802174A - 用于治疗神经系统病症的苏拉明的鼻内施用 - Google Patents

用于治疗神经系统病症的苏拉明的鼻内施用 Download PDF

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Publication number
CN116802174A
CN116802174A CN202180085815.2A CN202180085815A CN116802174A CN 116802174 A CN116802174 A CN 116802174A CN 202180085815 A CN202180085815 A CN 202180085815A CN 116802174 A CN116802174 A CN 116802174A
Authority
CN
China
Prior art keywords
suramin
mice
weeks
patient
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180085815.2A
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English (en)
Chinese (zh)
Inventor
迈克尔·德比
扎卡里·罗梅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parks Medical Co ltd
Original Assignee
Parks Medical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parks Medical Co ltd filed Critical Parks Medical Co ltd
Publication of CN116802174A publication Critical patent/CN116802174A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN202180085815.2A 2020-10-22 2021-10-20 用于治疗神经系统病症的苏拉明的鼻内施用 Pending CN116802174A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063104350P 2020-10-22 2020-10-22
US63/104,350 2020-10-22
PCT/US2021/055908 WO2022087174A1 (en) 2020-10-22 2021-10-20 Intranasal administration of suramin for treating nervous system disorders

Publications (1)

Publication Number Publication Date
CN116802174A true CN116802174A (zh) 2023-09-22

Family

ID=81289355

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180085815.2A Pending CN116802174A (zh) 2020-10-22 2021-10-20 用于治疗神经系统病症的苏拉明的鼻内施用

Country Status (8)

Country Link
US (1) US20230390226A1 (enExample)
EP (1) EP4229035A4 (enExample)
JP (1) JP2023546923A (enExample)
CN (1) CN116802174A (enExample)
AU (1) AU2021366666A1 (enExample)
CA (1) CA3194818A1 (enExample)
IL (1) IL302223A (enExample)
WO (1) WO2022087174A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11080495B2 (en) * 2018-10-25 2021-08-03 Unified Information Devices, LLC Animal motion and temperature monitoring
CN116867487A (zh) * 2020-07-29 2023-10-10 完美日光有限公司 苏拉明的制造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110494140A (zh) * 2017-02-09 2019-11-22 完美日光有限公司 用于自闭症谱系障碍药物治疗的方法
US20200030265A1 (en) * 2017-02-08 2020-01-30 Csp Pharma, Inc. Antipurinergic compounds and uses thereof
CN114340597A (zh) * 2019-06-07 2022-04-12 帕克斯医学有限公司 用于治疗中枢神经系统障碍的组合物和方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200030265A1 (en) * 2017-02-08 2020-01-30 Csp Pharma, Inc. Antipurinergic compounds and uses thereof
CN110494140A (zh) * 2017-02-09 2019-11-22 完美日光有限公司 用于自闭症谱系障碍药物治疗的方法
CN114340597A (zh) * 2019-06-07 2022-04-12 帕克斯医学有限公司 用于治疗中枢神经系统障碍的组合物和方法

Also Published As

Publication number Publication date
US20230390226A1 (en) 2023-12-07
AU2021366666A1 (en) 2023-06-15
JP2023546923A (ja) 2023-11-08
EP4229035A4 (en) 2024-07-31
CA3194818A1 (en) 2022-04-28
IL302223A (en) 2023-06-01
WO2022087174A1 (en) 2022-04-28
AU2021366666A9 (en) 2024-02-08
EP4229035A1 (en) 2023-08-23

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Application publication date: 20230922