CN116764104A - System and method for regulating and controlling head and neck lymph - Google Patents
System and method for regulating and controlling head and neck lymph Download PDFInfo
- Publication number
- CN116764104A CN116764104A CN202310570503.1A CN202310570503A CN116764104A CN 116764104 A CN116764104 A CN 116764104A CN 202310570503 A CN202310570503 A CN 202310570503A CN 116764104 A CN116764104 A CN 116764104A
- Authority
- CN
- China
- Prior art keywords
- stimulation
- information
- head
- lymphatic
- neck
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000002751 lymph Anatomy 0.000 title claims abstract description 62
- 238000000034 method Methods 0.000 title claims abstract description 24
- 230000001105 regulatory effect Effects 0.000 title description 9
- 230000001276 controlling effect Effects 0.000 title description 7
- 230000000638 stimulation Effects 0.000 claims abstract description 145
- 230000001926 lymphatic effect Effects 0.000 claims abstract description 66
- 230000033228 biological regulation Effects 0.000 claims abstract description 54
- 238000012545 processing Methods 0.000 claims abstract description 37
- 238000001514 detection method Methods 0.000 claims abstract description 9
- 238000009826 distribution Methods 0.000 claims description 22
- 230000010365 information processing Effects 0.000 claims description 10
- 238000002604 ultrasonography Methods 0.000 claims description 9
- 230000010354 integration Effects 0.000 claims description 8
- 238000003709 image segmentation Methods 0.000 claims description 4
- 238000013507 mapping Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 21
- 230000009471 action Effects 0.000 abstract description 12
- 210000004556 brain Anatomy 0.000 abstract description 10
- 210000004698 lymphocyte Anatomy 0.000 abstract description 6
- 210000005036 nerve Anatomy 0.000 abstract description 2
- 210000003128 head Anatomy 0.000 description 55
- 210000001165 lymph node Anatomy 0.000 description 34
- 210000001365 lymphatic vessel Anatomy 0.000 description 21
- 238000005516 engineering process Methods 0.000 description 10
- 210000004324 lymphatic system Anatomy 0.000 description 8
- 230000006870 function Effects 0.000 description 6
- 210000000987 immune system Anatomy 0.000 description 6
- 230000003993 interaction Effects 0.000 description 5
- 238000012544 monitoring process Methods 0.000 description 5
- 210000004204 blood vessel Anatomy 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 238000009169 immunotherapy Methods 0.000 description 3
- 210000003563 lymphoid tissue Anatomy 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000012806 monitoring device Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 210000004761 scalp Anatomy 0.000 description 3
- 230000008685 targeting Effects 0.000 description 3
- 210000004881 tumor cell Anatomy 0.000 description 3
- 208000024827 Alzheimer disease Diseases 0.000 description 2
- 102000013455 Amyloid beta-Peptides Human genes 0.000 description 2
- 108010090849 Amyloid beta-Peptides Proteins 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 230000036760 body temperature Effects 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 210000005073 lymphatic endothelial cell Anatomy 0.000 description 2
- 210000005210 lymphoid organ Anatomy 0.000 description 2
- 238000007726 management method Methods 0.000 description 2
- 210000002569 neuron Anatomy 0.000 description 2
- 238000013421 nuclear magnetic resonance imaging Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 206010033675 panniculitis Diseases 0.000 description 2
- 230000000258 photobiological effect Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 208000014644 Brain disease Diseases 0.000 description 1
- 108090000312 Calcium Channels Proteins 0.000 description 1
- 102000003922 Calcium Channels Human genes 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 102000000634 Cytochrome c oxidase subunit IV Human genes 0.000 description 1
- 108090000365 Cytochrome-c oxidases Proteins 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 102000009520 Vascular Endothelial Growth Factor C Human genes 0.000 description 1
- 108010073923 Vascular Endothelial Growth Factor C Proteins 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 238000013170 computed tomography imaging Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000002567 electromyography Methods 0.000 description 1
- 238000002001 electrophysiology Methods 0.000 description 1
- 230000007831 electrophysiology Effects 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000012905 input function Methods 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 210000004880 lymph fluid Anatomy 0.000 description 1
- 230000003692 lymphatic flow Effects 0.000 description 1
- 210000004373 mandible Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003739 neck Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 230000004770 neurodegeneration Effects 0.000 description 1
- 208000015122 neurodegenerative disease Diseases 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 210000002741 palatine tonsil Anatomy 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000008844 regulatory mechanism Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 230000003238 somatosensory effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 238000004148 unit process Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
- A61B5/33—Heart-related electrical modalities, e.g. electrocardiography [ECG] specially adapted for cooperation with other devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/067—Radiation therapy using light using laser light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0652—Arrays of diodes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Pulmonology (AREA)
- Optics & Photonics (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The application relates to the technical field of nerve regulation, in particular to a head and neck lymph regulation system and a head and neck lymph regulation method. The system comprises a detection module, a data processing module, a control module and a stimulation module, wherein the stimulation module utilizes noninvasive external stimulation of a light source to regulate and control the superficial lymph of the brain, so that lymphatic drainage is promoted, and lymphocyte activity and function are enhanced. In addition, the characteristics of easy control of the light source action range and simple equipment are utilized, the accuracy of lymph regulation and control is improved, the use cost is reduced, and the application range of the system is enlarged.
Description
Technical Field
The application relates to the technical field of nerve regulation, in particular to a head and neck lymph regulation system and a head and neck lymph regulation method.
Background
The lymphatic system is an important component of the human immune system, and has the effects of maintaining humoral balance and participating in immune response. In anatomy, the system specifically includes lymphatic vessels, lymphoid tissues and lymphoid organs, wherein lymphoid organs consist of lymph nodes, thymus, spleen, tonsils, etc. To assist venous return and to participate in the immune process, the fluid located in the lymphatic vessels and in the lymphatic sinuses of the lymph nodes, lymph, plays an important role.
Researchers have concluded that lymphatic drainage techniques can increase lymphatic return rate by deeply knowing the anatomy of the lymphatic system in combination with clinical edema cases, thereby reducing the extent of edema in patients. Besides promoting the flow of lymph and improving circulation, the lymphatic drainage can also enhance the activity and the function of lymphocytes and improve the efficiency of an immune system.
In 2015, researchers at the university of virginia medical school discovered that the brain of mice would be directly coupled to the immune system through lymphatic vessels, which linked the lymphatic system to the brain's mechanisms of operation and brain disease. Further, it was found that lymphatic drainage of the brain has a remarkable effect in promoting apoptosis of tumor cells. In 2020, akikoIwasaki et al found that lymphatic drainage driven by vascular endothelial growth factor C can promote the growth and expansion of lymphatic vessels around brain tumors, increase lymphatic drainage, increase the degree of immune cell infiltration, and further promote the removal of tumor cells and inhibit the growth of tumor cells. In addition to tumor-related brain lymphatic drainage studies, there are teams that find brain lymph to be associated with Alzheimer's disease. As the most common cause of dementia, alzheimer's disease is characterized by the massive deposition of toxic Amyloid β (aβ) in the brain, and currently the more effective treatment is passive immunotherapy using monoclonal antibodies against Amyloid β.2021, sandroDaMesquita et al found that meningeal lymphatic drainage played a critical role in sediment removal and anti-amyloid β immunotherapy, and that by activating meningeal lymphatic vessels, the patient's response to immunotherapy could be enhanced, improving efficacy.
Thus, a series of products or methods for stimulating head and neck lymph by external action, such as head lymph massage apparatus, have been devised. The massage device utilizes the drainage pump and the inflatable head sleeve to conduct push type drainage on lymphatic system at the front, back and lower jaw of human ears, thereby realizing the purpose of promoting lymphatic flow. However, the product also has obvious defects: firstly, the air pump is adopted to press the inflatable head cover to be in contact with the skin, so that discomfort of a user can be caused, or the risk of infection is increased, and the adaptability of the head cover is also a problem due to individual variability; secondly, the action position and the action depth of the stimulation method are limited, so that the stimulation method can only act on part of lymphoid tissues, and the drainage effect is poor; finally, the operation of pressing by using the air pump makes the time resolution and the space resolution of the device lower, and the time cannot be controlled accurately or the local lymphatic stimulation can be completed.
Aiming at the problems of easy personnel discomfort, limited action mode, low space-time resolution and the like, researchers develop a technology for regulating and controlling lymph by using a physical field. As an emerging neuroscience technology, the basic idea of physical field regulation is to act on brain neurons through a non-invasive physical field to achieve control of brain neural activity. At present, main physical field regulation and control technologies comprise magnetic stimulation, ultrasonic stimulation, electric stimulation and the like, and have the advantages that on one hand, the stimulation can directly act on target cells, and the accurate control of neuron activity can be realized by regulating parameters; on the other hand, the technology has the characteristics of non-invasiveness, repeatability, adjustability and the like, and avoids potential risks and adverse effects possibly brought by the traditional treatment methods such as surgery and the like. Therefore, the physical field regulation and control technology is applied to the lymphatic drainage scene, so that the adaptability of a user can be improved, drainage can be completed by safer and more comfortable means, the adjustability of stimulation parameters can be improved, and higher space-time resolution and accurate stimulation effect can be achieved.
Currently, the part of researchers using physical fields for lymphatic regulation is mainly concentrated at the limb lymphatic vessels instead of the head and neck, which is related to the reasons of complicated head and neck lymphatic regulation mechanism and the like, so that the physical field regulation technology is limited to the part and only applied to specific lymphatic positions. Although teams realize physical field regulation of meningal lymph by using magnetic stimulation and ultrasonic stimulation, the method uses electromagnetic coils or ultrasonic transducers and the like as stimulus sources, and the area regulated by a single stimulus source is larger, so that the accuracy of lymph regulation is lower. In addition, when the instrument with fixed stimulus distribution is used for lymphatic regulation, the instrument can be influenced by the lymphatic distribution difference among different individuals, and the regulation accuracy is further reduced. Meanwhile, the device for executing the stimulation is complex, the device is narrow in adaptation scene due to the characteristics of high manufacturing cost and more use precautions, and the device cannot meet the existing requirements and needs to be solved.
Disclosure of Invention
The present application aims to overcome the deficiencies of the prior art and to solve at least one of the drawbacks of the prior art described above.
In order to achieve the above purpose, the present application provides the following technical solutions:
in a first aspect of the application, there is provided a head and neck lymphatic regulation system comprising: the detection module is used for collecting head and neck lymphatic image information; the data processing module is used for acquiring lymphatic distribution information according to the head and neck lymphatic image information; the control module is used for acquiring stimulation information according to the lymphatic distribution information, wherein the stimulation information comprises infrared light stimulation selection and/or visible light stimulation selection; and a stimulation module for executing stimulation operation according to the stimulation information.
In some embodiments, the head and neck lymph regulation system further comprises an information feedback module for collecting user feedback information and transmitting the user feedback information to the data processing module.
In some embodiments, the data processing module comprises: an image data processing unit for processing the head and neck lymphatic image information; the feedback information processing unit is used for processing the user feedback information; and a data integration unit integrating the information of the image data processing unit and the feedback information processing unit and outputting data to the control module.
In some embodiments, the image data processing unit performs image segmentation on the head and neck lymph image information to obtain the position, size, shape and number of head and neck lymph.
In some embodiments, the infrared light stimulus comprises a near infrared light stimulus having a wavelength of 800-1100 nm; and the visible light stimulus comprises a red light stimulus with a wavelength of 622-760nm and/or a blue light stimulus with a wavelength of 450-490 nm.
In some embodiments, the stimulation module is an array of light emitting diodes and/or lasers.
In some embodiments, the stimulation information further includes an ultrasound stimulation selection, and the stimulation module performs ultrasound stimulation in accordance with the ultrasound stimulation selection.
In some embodiments, the stimulation information further comprises: stimulus intensity, stimulus frequency, stimulus duration, stimulus period, temperature, and/or pulse width.
In some embodiments, the control module includes: and the illness state information processing unit is used for identifying the user category through the user illness state information and outputting the stimulus information to the stimulus module according to the mapping relation between the user category and the stimulus information.
In a second aspect of the present application, a method for regulating and controlling head and neck lymph comprises: collecting head and neck lymphatic image information; obtaining lymphatic distribution information according to the head and neck lymphatic image information; obtaining stimulation information according to the lymphatic distribution information, wherein the stimulation information comprises infrared light stimulation selection and/or visible light stimulation selection; and performing a stimulation operation according to the stimulation information.
Compared with the prior art, the application has the beneficial effects that,
(1) The head and neck lymph regulation system and the head and neck lymph regulation method provided by the application utilize the photo-biological regulation therapy to regulate and control the head and neck shallow lymph, so that the activity and the function of lymphocytes are enhanced while the lymph flow is promoted and the circulation is improved, and the efficiency of an immune system is improved.
(2) The head and neck lymph regulation and control system provided by the application is provided with the light stimulation device, and the targeting of stimulation to the action area is improved by utilizing the characteristic that the action range of the light source is easy to control, so that the lymph regulation and control accuracy is improved.
(3) The head and neck lymph regulation system provided by the application adopts light-emitting diodes or lasers and other light stimulation devices which are simpler, has low manufacturing cost and simple and convenient use, so that the system has wider application scenes, and provides a new idea for the portable development of lymph regulation.
(4) The head and neck lymph regulation and control system provided by the application is provided with the detection module and the data processing module, and the distribution information of the data such as lymph position, size and dimension is obtained by collecting the lymph image information and carrying out image segmentation and other algorithm processing on the lymph image information, so that the targeting property, the accuracy and the regulation and control effect of lymph regulation and control are improved.
(5) The head and neck lymph regulation system provided by the application is provided with the data integration unit in the data processing module, the data integration unit integrates the lymph distribution information and the user feedback information to make an optimal decision, and outputs the stimulation mode and the stimulation parameter information to the control module to guide the execution of the follow-up stimulation module.
(6) The head and neck lymph regulation system provided by the application is provided with a plurality of mode selection functions in the control module, and a proper stimulation mode is selected according to individual demand difference to execute stimulation, so that the individual adaptability of the system is improved.
Drawings
FIG. 1 is a block diagram of a head and neck lymphatic regulation system in one embodiment;
FIG. 2 is a block diagram of a data processing module in one embodiment;
FIG. 3 is a block diagram of a control module in one embodiment;
fig. 4 is a flowchart of a method of head and neck lymphatic regulation in an embodiment.
Detailed Description
The technical solutions of the present patent will be described in further detail below with reference to specific embodiments, and it should be noted that the following detailed description is exemplary, and is intended to provide further explanation of the present application. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.
The lymphatic stimulation area in the embodiment of the application comprises the superficial lymph of the head and neck, namely lymph nodes and lymphatic vessels which are mainly distributed on the superficial parts of the human body of skin and subcutaneous tissue.
As an important component of the lymphatic system, the lymph nodes are internally provided with abundant lymphocytes and lymphoid tissues and are connected with a plurality of lymphatic vessels, and the positions of the lymph nodes are relatively fixed. The superficial lymph nodes of the head and neck part according to the embodiment of the application are mainly divided into the following four areas: the first group of submandibular lymph nodes positioned at the junction of the mandible and the neck can be divided into a left group and a right group, and is one of the largest lymph node groups in the head and neck lymphatic system; secondly, the lymph node group of the throat which is positioned on the anterior midline of the neck and distributed along the midline of the throat and the neck can be divided into annular retropharyngeal lymph nodes, sublaryngeal lymph nodes, lymph nodes at the boundary of the trachea and esophagus, and the like; third, a cervical lymph node group located on the side of the neck, including upper cervical lymph node, posterior cervical lymph node, anterior cervical lymph node, posterior cervical triangle lymph node, etc.; fourth, the group of head lymph nodes located on the lateral and posterior sides of the head, including the retroauricular lymph nodes, occipital lymph nodes, forehead lymph nodes, and the like.
Accordingly, the superficial lymphatic vessels of the head and neck are mainly divided into the following four categories: firstly, a superficial lymphatic vessel of the face, which is positioned in the tissue under the skin of the face, is distributed along the blood vessel of the face and is converged into a lymph node of the face; secondly, the superficial lymphatic vessels of the scalp are positioned in subcutaneous tissue of the scalp, distributed along scalp blood vessels and converged into cervical lymph nodes; thirdly, a pharyngeal superficial lymphatic vessel which is positioned in a pharyngeal submucosal tissue and distributed along pharyngeal blood vessels to be converged into pharyngeal lymph nodes; and fourthly, superficial lymphatic vessels of the neck, which are positioned in the skin and the sub-fascia tissues of the neck, are distributed along the blood vessels of the neck and are converged into cervical lymph nodes.
The embodiment of the application provides a head and neck lymph regulation system and a head and neck lymph regulation method based on the distribution characteristics of human lymphatic vessels and lymph nodes. The system and the method realize the regulation and control of the head and neck shallow lymph by collecting and analyzing the lymph distribution condition of the target area, selecting proper stimulation modes and corresponding parameters and executing stimulation operation. In addition, the accuracy of lymph regulation and control is improved by setting the light stimulation mode, the use cost is reduced, and the whole application range is enlarged.
Example 1:
as shown in fig. 1, the embodiment provides a head and neck lymph regulation system, which comprises a detection module, a data processing module, a control module, a stimulation module, an information feedback module and a power management module.
The detection module is used for acquiring image information of lymphatic distribution and transmitting data to the data processing module, the data processing module converts the data into various data of lymphatic vessels and lymph nodes by using an algorithm, and converts the data into proper stimulation modes and stimulation parameters by the control module, so that a stimulation effect is generated under the action of the stimulation module. The information feedback module is an auxiliary module and is used for feeding back subjective information of a user, further fine-tuning part of stimulation parameters, and the power management module is used for managing the power supply of the system so as to ensure stable operation of the system.
Specifically, the detection module in this embodiment adopts ultrasonic contrast imaging technologies such as B-mode ultrasound and color doppler ultrasound to perform detection so as to acquire head-neck shallow lymph image data, and may also acquire data by methods such as electronic computed tomography and nuclear magnetic resonance imaging technologies. The module improves the accuracy of the stimulation target area on one hand, has good controllability on the other hand, and can flexibly control various parameters according to the target area, so that the system has higher safety and better stimulation effect.
The data processing module receives the information of the detection module and the information feedback module, performs calculation integration, and further transmits data to the control module. The structure of the module is shown in fig. 2, and comprises an image data processing unit, a feedback information processing unit and a data integration unit. The image data processing unit calculates and analyzes various information such as the position, the size, the shape, the number, the blood flow and the like of lymph by utilizing the acquired head and neck image information through image processing algorithms such as preprocessing of a microprocessor, image segmentation and the like; the feedback information processing unit processes and analyzes the content fed back by the user by utilizing the microcontroller so as to obtain information such as somatosensory and the like; the data integration unit analyzes and integrates the information of the image data processing unit and the feedback information processing unit to form a three-dimensional stimulation navigation image, and then adjusts the control module. In addition, a man-machine interaction interface can be further arranged to visualize the data results of the image data processing unit and the data integration unit so as to display the information such as the positions, the sizes, the shapes, the number and the like of the lymphatic vessels and the lymph nodes of the user, and further the data processing mode is manually interfered. Meanwhile, the data processing module may specifically include one or more terminal devices.
The control module is a main control module of the system and is used for receiving the information of the data processing module to adjust the stimulation parameters and transmitting the data to the stimulation module to realize the regulation and control of the physical field on the head and neck shallow lymph. The structure of the control module is shown in fig. 3, and comprises a microprocessor, an ultrasonic control unit, an infrared control unit, a visible light control unit, a man-machine interaction interface and the like. And the microprocessor respectively controls corresponding ultrasonic stimulation, infrared stimulation and visible light stimulation according to the instruction output by the data processing module. In addition, the control module may specifically include one or more terminal devices, or may use one or more terminal devices together with the data processing module.
Meanwhile, the control module is provided with a man-machine interaction interface and bears input functions such as inputting feedback information and the like so as to perform manual intervention on each control unit, wherein the intervention content comprises mode selection, parameter setting and the like. And in particular may include, but is not limited to, infrared light stimulation modes, visible light stimulation modes, ultrasound stimulation modes, etc., as well as parameters such as stimulation intensity, stimulation frequency, stimulation duration, stimulation period, temperature, and light pulse width.
Furthermore, the control module can be further provided with a disease information processing unit, the unit collects disease data and lymph information such as diagnosis reports, medical records and physical examination reports of the user through a manual interaction interface, analyzes and processes the disease data and lymph information to determine the category of the user, and further realizes automatic selection of a stimulation mode and stimulation parameters according to the mapping relation between the category of the user and stimulation to guide execution of a follow-up stimulation module. The mapping relationship between the user category and the stimulation mode and parameters can be preset manually or can be determined by analyzing a large amount of illness state data. It should be noted that, the weights of the data items in the illness state information of the user may be different, and some data items with a great influence on health or safety may have a great weight, for example, a certain user is allergic to infrared stimulation, and the stimulation mode corresponding to the user may only be a visible light stimulation mode or an ultrasonic stimulation mode.
The stimulation module is used for generating non-invasive physical stimulation, and the target area is the superficial lymphatic system of the head and neck and lymph nodes or other positions. The stimulation module utilizes the physical field to stimulate the target position, and can specifically adopt a light stimulation device or an ultrasonic stimulation device, or can adopt the light stimulation device and the ultrasonic stimulation device at the same time. In addition to the stimulation performed in a plurality of modes, when the stimulation is performed in a plurality of modes, the stimulation in different modes can be performed independently, or can be performed alternately or simultaneously, for example, the optical stimulation and the ultrasonic stimulation are applied alternately to the user.
In particular, the main area targeted by the different stimulation devices may vary. The light stimulation device in this embodiment adopts a light emitting diode array and a laser, the light emitting diode arrays are arranged closely according to the distribution position of lymphatic vessels, the laser mainly acts in the area where lymph nodes are enriched, and the rest part adopts a hollowed-out or breathable design with good heat dissipation. Besides, the distribution rule of lymphatic vessels and lymph nodes can be followed, so that the light emitting diode array completely covers common lymphatic vessels and lymph nodes and the like. The mode of utilizing the light stimulus to carry out lymph regulation has the characteristics of adjustable stimulus source action range, reduced volume, simple device and the like, on one hand, the targeting property of stimulus to an action area is improved, the accuracy of lymph regulation is improved, on the other hand, the manufacturing cost is reduced, the use convenience is improved, the system has wider application scenes, and the potential of developing towards portable equipment is shown. Also, similar to the distribution of lasers, ultrasonic stimulation is also applied to areas where lymph nodes are more concentrated.
In addition, the light stimulation device for photo bio-modulation therapy may output infrared light stimulation and/or visible light stimulation, such as near infrared light having a wavelength of 800-1100nm, red light having a wavelength of 622-760nm, blue light having a wavelength of 450-490nm, etc. Under the action of the light source, various lymphatic regulation and control effects can be generated, for example, the shape and the function of lymphatic vessels are influenced by utilizing the photo-thermal effect or the photo-biological effect generated by near infrared light with the wavelength of 808nm, and the proliferation and the expansion of lymphatic endothelial cells are promoted, so that the lymphatic circulation and the lymphatic fluid removal capacity are promoted; light with the wavelength of 600-850nm is utilized to act on cytochrome C oxidase, so that intracellular ATP generation is promoted, and the cell activity is improved; the light with the wavelength of 900-1100nm is utilized to act on a calcium ion channel on the surface of the cell, so as to promote the inflow of calcium ions and regulate the electrical activity of the cell; red light is utilized to improve blood flow, increase tissue metabolism and promote the flow of lymph fluid; stimulating lymphatic endothelial cells by using blue light, promoting the flow of lymphatic fluid and improving anti-inflammatory effect; in addition, lymphatic drainage and the like can be promoted by photo-thermal effect. Therefore, the lymphatic regulation and control by using the light stimulation can promote lymphatic drainage, enhance lymphocyte activity and function, improve immune system efficiency, improve individual health level and assist in treating neurodegenerative diseases. When the ultrasonic stimulation device is adopted, the ultrasonic wave with the frequency of 1-10MHz can be selected for regulation and control according to the acoustic effect and biological effect of the ultrasonic stimulation device.
In addition, the stimulation module can be a wearable stimulation device with any shape, such as a hat-shaped flexible shell and the like, so that comfort and experience of a user in the regulation and control process are improved. In specific application, the LED, the laser or the array element transducer and the like can be assembled in the flexible shell, so that the flexible shell has the characteristic of being wearable.
The information feedback module can complete information feedback by matching with a human-computer interaction interface based on subjective information of a user which is inquired by a professional, such as stimulus intensity, heat and whether discomfort exists. However, the situation that misjudgment is possible to occur is completely relied on subjective feeling of a user, so that the embodiment is further provided with an electrophysiological monitoring unit and a body temperature monitoring unit, and closed-loop information feedback is realized by means of modern medical means. The electrophysiological monitoring unit is specifically an electroencephalogram monitoring device, an electrocardiographic monitoring device, an electromyography monitoring device and the like, such as a conventional 12-lead electrocardiogram and a multichannel electroencephalogram. Parameters such as heart rate, blood oxygen and blood oxygen saturation can be calculated based on data such as brain electricity, electrocardio, myoelectricity and body temperature fed back by the two monitoring units. User feedback information acquired by the information feedback module is transmitted to the data processing module and the control module, so that on one hand, the user feedback information can be displayed through display equipment such as a display screen and the like, the physiological state of the user can be known in time, and on the other hand, the stimulation parameters can be adjusted in real time according to the feedback parameters, the stimulation effect is improved, and personalized stimulation is realized.
Example 2:
as shown in fig. 4, the present embodiment provides a method for regulating and controlling head and neck lymph, which is executed by the above-mentioned head and neck lymph regulating and controlling system, and includes S1, collecting head and neck lymph image information;
s2, acquiring lymphatic distribution information according to the head and neck lymphatic image information; s3, acquiring stimulation information such as infrared light stimulation selection and/or visible light stimulation selection according to the lymphatic distribution information; s4, executing the stimulation operation according to the stimulation information.
Specifically, the step of S1, acquiring the head and neck lymphatic image information refers to acquiring the head and neck shallow lymphatic image data by using an ultrasonic contrast imaging technology, an electronic computer tomography, a nuclear magnetic resonance imaging technology and the like.
S2, acquiring lymphatic distribution information according to the head and neck lymphatic image information refers to calculating and analyzing various information such as the position, the size, the shape, the number, the blood flow and the like of the lymph by utilizing the acquired head and neck lymphatic image information through an image processing algorithm of a microprocessor.
S3, acquiring stimulation information according to the lymphatic distribution information refers to selecting a proper stimulation mode and stimulation parameters by utilizing the acquired position information. Specifically, the method can be selected from infrared light stimulation selection, visible light stimulation selection, ultrasonic stimulation selection and the like, and parameters such as stimulation intensity, stimulation frequency, stimulation duration, stimulation period, temperature, pulse width and the like are selected.
S4, performing stimulation operation according to the stimulation information refers to non-invasive physical stimulation to the target area by utilizing a light source or ultrasonic waves, wherein specific targets comprise superficial lymphatic vessels of the head and neck and superficial lymphatic systems of lymph nodes or other positions.
Further, the method for regulating and controlling the head and neck lymph can further comprise S5, acquiring feedback parameters and adjusting stimulation information in a closed loop mode according to the feedback parameters, specifically, acquiring feedback indexes by acquiring subjective responses of users or monitoring the user information by utilizing electrophysiology, so as to adjust stimulation modes and stimulation parameters.
In summary, the application provides a head and neck lymph control system and a head and neck lymph control method, which utilize noninvasive external stimulation of a light source to control the superficial cerebral lymph, promote lymphatic drainage, enhance lymphocyte activity and function, promote immune system efficiency and improve individual health level. In addition, the characteristics of easy control of the light source action range and simple equipment are utilized, the accuracy of lymph regulation and control is improved, the use cost is reduced, and the application range of the system is enlarged.
The foregoing are merely some embodiments of the application. It will be apparent to those skilled in the art that various modifications and improvements can be made without departing from the spirit of the application.
Claims (10)
1. A head and neck lymphatic regulation system, comprising:
the detection module is used for collecting head and neck lymphatic image information;
the data processing module is used for acquiring lymphatic distribution information according to the head and neck lymphatic image information;
the control module is used for acquiring stimulation information according to the lymphatic distribution information, wherein the stimulation information comprises infrared light stimulation selection and/or visible light stimulation selection; and
and the stimulation module is used for executing stimulation operation according to the stimulation information.
2. The head and neck lymphatic regulation system according to claim 1, further comprising:
and the information feedback module is used for collecting user feedback information and transmitting the user feedback information to the data processing module.
3. The head and neck lymphatic regulation system of claim 2, wherein the data processing module comprises:
an image data processing unit for processing the head and neck lymphatic image information;
the feedback information processing unit is used for processing the user feedback information; and
and the data integration unit integrates the information of the image data processing unit and the feedback information processing unit and outputs data to the control module.
4. The head and neck lymph control system according to claim 3, wherein the image data processing unit performs image segmentation on the head and neck lymph image information to obtain the position, size, shape and number of head and neck lymph.
5. The head and neck lymphatic regulation system according to any of claims 1-4, wherein said infrared light stimulus comprises a near infrared light stimulus having a wavelength of 800-1100 nm; and
the visible light stimulus comprises a red light stimulus with a wavelength of 622-760nm and/or a blue light stimulus with a wavelength of 450-490 nm.
6. The head and neck lymphatic regulation system according to claim 5, wherein the stimulation module is an array of light emitting diodes and/or a laser.
7. The head and neck lymphatic regulation system of claim 6, wherein the stimulation information further comprises an ultrasound stimulation selection, the stimulation module performing ultrasound stimulation in accordance with the ultrasound stimulation selection.
8. The head and neck lymphatic regulation system according to claim 7, wherein the stimulation information further comprises:
stimulus intensity, stimulus frequency, stimulus duration, stimulus period, temperature, and/or pulse width.
9. The head and neck lymphatic regulation system of claim 8, wherein the control module comprises:
and the illness state information processing unit is used for identifying the user category through the user illness state information and outputting the stimulus information to the stimulus module according to the mapping relation between the user category and the stimulus information.
10. A method of lymphatic regulation in the head and neck, comprising:
collecting head and neck lymphatic image information;
obtaining lymphatic distribution information according to the head and neck lymphatic image information;
obtaining stimulation information according to the lymphatic distribution information, wherein the stimulation information comprises infrared light stimulation selection and/or visible light stimulation selection; and
and executing the stimulation operation according to the stimulation information.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310570503.1A CN116764104A (en) | 2023-05-19 | 2023-05-19 | System and method for regulating and controlling head and neck lymph |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310570503.1A CN116764104A (en) | 2023-05-19 | 2023-05-19 | System and method for regulating and controlling head and neck lymph |
Publications (1)
Publication Number | Publication Date |
---|---|
CN116764104A true CN116764104A (en) | 2023-09-19 |
Family
ID=87992062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310570503.1A Pending CN116764104A (en) | 2023-05-19 | 2023-05-19 | System and method for regulating and controlling head and neck lymph |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN116764104A (en) |
-
2023
- 2023-05-19 CN CN202310570503.1A patent/CN116764104A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20150174418A1 (en) | Device and Methods for Noninvasive Neuromodulation Using Targeted Transcranial Electrical Stimulation | |
US11986667B2 (en) | Methods and devices for photobiomodulation | |
US9486389B2 (en) | Apparatus and method for calibrating non-invasive desynchronizing neurostimulation | |
CN103284878B (en) | Intelligent massage appliance | |
CN105431201B (en) | System and method for providing phototherapy and adjusting circadian rhythm | |
US11730960B2 (en) | Ultrasound systems and associated devices and methods for modulating brain activity | |
CN108187236B (en) | Multifunctional hair growth instrument and system | |
US20230285772A1 (en) | Head wearable light therapy device | |
CN110801580A (en) | Brain light stimulation regulation and control device | |
CN110269993A (en) | A kind of application method of sleep guidance device, system and system | |
CN115253072A (en) | Multi-mode deep electroencephalogram stimulation accurate nerve regulation and control system and method | |
WO2022197937A1 (en) | Methods and devices for photobiomodulation | |
CN115212469A (en) | Light therapy device for treating psychological disorders including depression | |
CN115887857A (en) | Multi-physical-factor stimulation nerve regulation and control device and method combining biofeedback | |
WO2021032803A1 (en) | Method for identifying an acupuncture point and/or a meridian | |
RU2336916C2 (en) | Device for physiotherapeutic treatment of various etiology diseases | |
US20220379142A1 (en) | Systems and methods for brain imaging and stimulation using super-resolution ultrasound | |
CN116764104A (en) | System and method for regulating and controlling head and neck lymph | |
Toomim et al. | Hemoencephalography: photonbased blood flow neurofeedback | |
CN114042257A (en) | Biological rhythm regulator for auxiliary treatment | |
TWI773944B (en) | Body physiotherapy machine | |
KR20220121108A (en) | High frequency high temperature curator having user's body feeling effect | |
CN116764092A (en) | Lymph node regulation and control system and method | |
CN219398616U (en) | Portable depression therapeutic instrument based on photobiological regulation effect | |
Ivanova et al. | Possibilities of Eeg Diagnostics For Evaluation of The Massage Effects |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |