CN116763868A - Traditional Chinese medicine formula for treating obesity and preparation method thereof - Google Patents

Traditional Chinese medicine formula for treating obesity and preparation method thereof Download PDF

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Publication number
CN116763868A
CN116763868A CN202210223203.1A CN202210223203A CN116763868A CN 116763868 A CN116763868 A CN 116763868A CN 202210223203 A CN202210223203 A CN 202210223203A CN 116763868 A CN116763868 A CN 116763868A
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control module
concentration
traditional chinese
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邓寅
谢成
谢培增
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Guangdong New Journey Life Science Research Institute
Guangdong Xinzhengcheng Life Science Co ltd
Guangzhou New Journey Biotechnology Co ltd
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Guangdong New Journey Life Science Research Institute
Guangdong Xinzhengcheng Life Science Co ltd
Guangzhou New Journey Biotechnology Co ltd
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Publication of CN116763868A publication Critical patent/CN116763868A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C21/00Disintegrating plant with or without drying of the material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C4/00Crushing or disintegrating by roller mills
    • B02C4/02Crushing or disintegrating by roller mills with two or more rollers
    • B02C4/08Crushing or disintegrating by roller mills with two or more rollers with co-operating corrugated or toothed crushing-rollers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C4/00Crushing or disintegrating by roller mills
    • B02C4/28Details
    • B02C4/30Shape or construction of rollers

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Abstract

The invention relates to a traditional Chinese medicine formula for treating obesity and a preparation method thereof, and relates to the technical field of traditional Chinese medicines, wherein the traditional Chinese medicine formula comprises the steps of conveying raw materials with preset mass parts into a crusher for shearing and crushing to obtain traditional Chinese medicine granules; the smashed medicinal powder is controlled to be sent into a boiling machine for boiling; filtering the decocted liquid medicine, and sending the filtered liquid medicine into a concentration tank for concentration; the concentrated liquid medicine is conveyed to a bagging machine to be prepared into a traditional Chinese medicine concentrate, and the traditional Chinese medicine concentrate is obtained in real time, so that whether the medicine property in the traditional Chinese medicine is completely exerted is determined according to the state of the traditional Chinese medicine, and when the traditional Chinese medicine concentrate is prepared, the traditional Chinese medicine concentrate is crushed into medicine particles and the medicine particles are sent to a boiling machine to be boiled, the medicine liquid is filtered after the boiling is finished, and then the medicine liquid is concentrated into a prepared medicine, so that the medicine property in the traditional Chinese medicine can be completely exerted, the accuracy of controlling the process is improved, and the preparation efficiency is improved.

Description

Traditional Chinese medicine formula for treating obesity and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine formula for treating obesity and a preparation method thereof.
Background
The Chinese herbal medicine is a traditional treatment method in China, and has the following advantages: firstly, the Chinese herbal medicines are various, a doctor can carry out scientific compatibility according to the symptoms and physical signs of a patient, four diagnosis and comprehensive analysis, and then carry out treatment on the symptoms, which is a model of individual treatment, secondly, the Chinese herbal medicines are mostly purely natural substances, do not contain any artificial additives, and have higher safety and effectiveness, but because of the various Chinese herbal medicines, the mixing treatment of the medicinal materials is inconvenient.
Obesity has been cast as a major factor threatening human health in modern society, as obesity caused by irregular diet of people in daily life directly or indirectly causes unhealthy body and mind of people, aiming at obesity, people can choose drugs and exercises to treat, but the existing weight-losing drugs on the market are generally western drugs, the short-term treatment effect can reach very high speed, but the possibility of rebound exists, the health of the human body cannot be ensured, the exercise is fat-reducing, although the effect is not obvious enough, people are difficult to adhere, and the traditional Chinese medicine is taken as a drug for treating diseases of thousands of years, so that the effect and health of treating obesity can be ensured to the human body.
However, in the prior art, when preparing the traditional Chinese medicine for treating obesity, the preparation process cannot be accurately controlled, so that the preparation efficiency is low, and the effect of the prepared therapeutic medicine cannot be optimal.
Disclosure of Invention
Therefore, the invention provides an obesity traditional Chinese medicine formula and a preparation method thereof, which are used for solving the problem that the preparation efficiency is low because the preparation process cannot be accurately controlled in the prior art.
In order to achieve the above purpose, one embodiment of the invention provides the obesity traditional Chinese medicine formula, wherein the first mixed material comprises 5-8 parts of rose, 10-15 parts of yam and 6-10 parts of seaweed, which are respectively dried in an oven at 80 ℃;
4.5-7 parts of astragalus mongholicus, 6-10 parts of ground bone, 3-5 parts of hawthorn, 10-12 parts of rhizoma atractylodis and 5-9 parts of radix salviae miltiorrhizae after being soaked in warm water at 60 ℃.
The preparation method of the traditional Chinese medicine for treating obesity, disclosed by the other embodiment of the invention, comprises the following steps:
s1, a control module controls the raw material medicines with preset mass parts to be conveyed into a crusher for shearing and crushing to obtain traditional Chinese medicine granules;
s2, the control module controls the smashed medicinal powder to be sent into a boiling machine for boiling;
s3, the control module controls the boiled liquid medicine to be filtered, and the filtered liquid medicine is sent into a concentration tank for concentration;
s4, the control module conveys the concentrated liquid medicine to a bagging machine to prepare a traditional Chinese medicine concentrate;
in the step S1, when the bulk drug is delivered to a crusher for crushing, the control module sets the initial rotation speed of the crusher to Va1.
In the step S2, when the powder is boiled, the control module sets the boiling temperature of the boiling machine to be T, and performs ultrasonic vibration during the boiling process, and the control module determines the ultrasonic vibration frequency according to the average particle size of the Chinese medicine particles and the particle size during the boiling process;
in the step S3, when the filtered liquid medicine is concentrated, the control module obtains the evaporation amount of the concentration tank, and determines whether the concentration is completed according to the evaporation amount.
Further, in the step S2, when determining the ultrasonic frequency, the control module sets the average particle diameter and the ultrasonic vibration frequency corresponding to the preset average particle diameter in the control module,
wherein the control module is provided with a first preset average particle diameter R1, a second preset average particle diameter R2, a third average particle diameter R3, a first ultrasonic frequency P1, a second ultrasonic frequency P2 and a third ultrasonic frequency P3, wherein R1 is more than R2 and less than R3, P1 is more than P2 and less than P3,
when R is less than or equal to R1, the control module sets the ultrasonic vibration frequency to P1;
when R1 is more than R and less than or equal to R2, the control module sets the ultrasonic vibration frequency to P2;
when R2 is less than R and less than or equal to R3, the control module sets the ultrasonic vibration frequency to P3.
Further, in the step S2, when the control module controls the decocting machine to perform decoction, the control module obtains the concentration W of the liquid medicine when the decoction is performed for a time period of t0, determines whether the decoction is completed according to a comparison result of the concentration W and a preset concentration W0,
if W is less than W0, the control module judges that the boiling is not finished;
and if W is more than or equal to W0, the control module judges that the boiling is finished.
Further, when the control module determines that the boiling is not completed, the control module calculates a concentration difference Δw between the concentration and a preset concentration, sets Δw=w0-W, selects a corresponding adjustment coefficient according to a comparison result of the concentration difference and the preset concentration difference, adjusts the ultrasonic vibration frequency, and sets the adjusted ultrasonic vibration frequency as Pn ', and sets Pn' =pn×kpi, wherein Kpi is a frequency adjustment coefficient.
Further, in the step S2, when the adjustment of the ultrasonic vibration frequency is completed, the control module compares the adjusted ultrasonic frequency Pn' with the maximum ultrasonic frequency Pmax in the control module,
if Pn' > Pmax, the control module judges that the ultrasonic vibration frequency exceeds the standard;
and if Pn' is less than or equal to Pmax, the control module judges that the ultrasonic vibration frequency is qualified.
Further, when the control module determines that the ultrasonic vibration frequency exceeds the standard, the control module calculates a frequency difference value Δp between the ultrasonic vibration frequency Pn 'and the maximum ultrasonic frequency Pmax after adjustment, sets Δp=p' -Pmax, selects a corresponding compensation coefficient according to a comparison result of the frequency difference value and a preset frequency difference value to compensate the working time length of the crusher, and sets the working time length of the crusher after compensation as t ', sets t' =tχ Ktj, wherein t is the initial working time length of the crusher, and Ktj is a time length compensation coefficient.
Further, in the step S3, when the control module determines whether the concentration is completed according to the evaporation amount, the control module compares the evaporation amount Q of the concentration tank with a preset evaporation amount Q0, and determines whether the concentration is completed according to the comparison result,
if Q is more than or equal to Q0, the control module judges that concentration is finished;
and if Q is less than Q0, the control module judges that concentration is not finished.
Further, the control module calculates an evaporation amount difference Δq between the evaporation amount Q and a preset evaporation amount Q0, sets Δq=q0-Q, and selects a corresponding adjustment coefficient concentration temperature according to a comparison result of the evaporation amount difference and the preset evaporation amount difference to adjust, and sets the adjusted concentration temperature as Tz ', and sets Tz' =tz×xe, wherein Xe is a concentration temperature adjustment coefficient.
Further, when the liquid medicine is concentrated, the control module obtains the concentration N of the liquid medicine and determines the concentration temperature of the concentration tank according to the comparison result of the concentration and the preset concentration,
wherein the control module is also provided with a first preset concentration N1, a second preset concentration N2, a third preset concentration N3, a first concentration temperature T1, a second concentration temperature T2 and a third concentration temperature T3, wherein N1 is more than N2 and less than N3, T1 is more than T2 and less than T3,
when N is less than or equal to N1, the control module sets the concentration temperature of the concentration tank to be T1;
when N1 is more than N and less than or equal to N2, the control module sets the concentration temperature of the concentration tank to be T2;
when N2 is less than N and less than or equal to N3, the control module sets the concentration temperature of the concentration tank to be T3.
Compared with the prior art, the method has the beneficial effects that in the preparation process, the states of the traditional Chinese medicines in the preparation equipment are obtained in real time, so that whether the medicine property in the traditional Chinese medicines is completely exerted is determined according to the states of the traditional Chinese medicines, the control accuracy of the control process is improved, and the preparation efficiency is improved.
Particularly, in the preparation process, the raw material medicines are smashed into the medicine granules, the medicine granules are sent into a boiling machine for boiling, and the medicine liquid is filtered and concentrated into the prepared medicine after the boiling is finished, so that the medicine property of the raw material medicines can be fully exerted.
Furthermore, the control module is provided with a plurality of average particle sizes and corresponding ultrasonic frequencies, and when the bulk drugs are smashed and boiled, the ultrasonic vibration frequency during boiling is determined according to the average particle sizes of the smashed drug particles, so that the control precision of the preparation process is further improved, and the preparation efficiency is further improved.
Further, when the invention is used for boiling, whether the boiling is finished is determined according to the concentration of the obtained liquid medicine, and when the boiling is determined, the boiling is determined according to the comparison result of the actual concentration and the preset concentration, so that the aim of accurately controlling the preparation process is fulfilled.
Further, the control module is provided with a plurality of preset concentration differences and frequency adjustment coefficients, when the concentration of the mixture is determined to be incomplete according to the concentration determination result, the concentration differences of the actual concentration and the preset concentration are calculated, and the corresponding adjustment coefficients are determined according to the comparison result of the concentration differences and the preset concentration differences to adjust the ultrasonic frequency, so that the control precision of the preparation process is further improved, and the preparation efficiency is further improved.
Further, the invention also sets the maximum ultrasonic frequency, after adjusting the ultrasonic frequency, determines whether the ultrasonic frequency is qualified according to the comparison result of the adjusted ultrasonic frequency and the maximum ultrasonic frequency, and when the ultrasonic frequency is unqualified, selects the corresponding time length compensation coefficient according to the frequency difference value of the ultrasonic frequency and the maximum ultrasonic frequency and the comparison result of the preset frequency difference value to adjust the working time length of the crusher, so that the particle size of the crushed bulk drug is smaller, the drug property is better exerted, and the control precision of the preparation process is further improved, thereby further improving the preparation efficiency.
Drawings
FIG. 1 is a schematic diagram of the preparation equipment of the obesity traditional Chinese medicine;
fig. 2 is a flow chart of a preparation method of the traditional Chinese medicine for treating obesity.
Detailed Description
In order that the objects and advantages of the invention will become more apparent, the invention will be further described with reference to the following examples; it should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
Preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the present invention, and are not intended to limit the scope of the present invention.
It should be noted that, in the description of the present invention, terms such as "upper," "lower," "left," "right," "inner," "outer," and the like indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, which are merely for convenience of description, and do not indicate or imply that the apparatus or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Furthermore, it should be noted that, in the description of the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art according to the specific circumstances.
Referring to fig. 1, a schematic diagram of a preparation apparatus of the obesity traditional Chinese medicine according to the present invention is shown;
the invention relates to a preparation device for preparing obesity traditional Chinese medicine, which comprises a box body 1,
the crusher 2 is arranged in the box body 1 and comprises a crushing part for crushing the crude drug and a cleaning part for cleaning the crushed crude drug, the crushing part is a pair of crushing rollers 21 which are symmetrically arranged, and the cleaning part is a cleaning fan 22 arranged below the crushing rollers;
the boiling machine 3 is arranged right below the crusher 2 in the box body, and the boiling machine 3 comprises a boiling groove 31 for containing crushed medicine particles, a stirring rod 32 arranged in the boiling groove and used for stirring the medicine liquid by ultrasonic vibration, and a heating wire (not shown in the figure) arranged at the bottom of the boiling groove;
the condensing tank 4 is arranged at the middle lower part of the two boiling machines 3, and the condensing tank 4 comprises a condensing bin 41 for recovering the steam during condensing, a heating rod 42 for heating, and a liquid level meter (not shown in the figure) for detecting the steam quantity in the condensing bin.
And the control module 5 is arranged at the lower part of the concentration tank and is respectively connected with the crusher 2, the boiling machine 3 and the concentration tank 4.
5-8 parts of rose, 10-15 parts of yam slices and 6-10 parts of seaweed, which are respectively dried in an oven at 80 ℃;
4.5-7 parts of astragalus mongholicus, 6-10 parts of ground bone, 3-5 parts of hawthorn, 10-12 parts of rhizoma atractylodis and 5-9 parts of radix salviae miltiorrhizae after being soaked in warm water at 60 ℃.
The first embodiment comprises the following raw materials in parts by mass: 5 parts of rose, 4.5 parts of astragalus, 6 parts of ground bone, 10 parts of Chinese yam, 3 parts of hawthorn, 10 parts of rhizoma atractylodis, 5 parts of red sage root and 6 parts of seaweed.
In the second embodiment, the medicine comprises the following raw materials in parts by mass: 7 parts of rose, 6 parts of astragalus, 8 parts of ground bone, 12 parts of Chinese yam, 4 parts of hawthorn, 11 parts of rhizoma atractylodis, 8 parts of red sage root and 8 parts of seaweed.
The third embodiment comprises the following bulk drugs in parts by mass: 6 parts of rose, 5 parts of astragalus, 8 parts of ground bone, 12 parts of Chinese yam, 3.5 parts of hawthorn, 11 parts of rhizoma atractylodis, 7 parts of red sage root and 8 parts of seaweed.
The fourth embodiment comprises the following bulk drugs in parts by mass: 8 parts of rose, 7 parts of astragalus, 10 parts of ground bone, 15 parts of Chinese yam, 5 parts of hawthorn, 12 parts of rhizoma atractylodis, 9 parts of red sage root and 10 parts of seaweed.
Referring to fig. 2, a flowchart of a preparation method of the traditional Chinese medicine for treating obesity according to the present invention is shown;
the preparation method of the traditional Chinese medicine for treating obesity comprises the following steps:
s1, a control module controls the raw material medicines with preset mass parts to be conveyed into a crusher for shearing and crushing to obtain traditional Chinese medicine granules;
s2, the control module controls the smashed medicinal powder to be sent into a boiling machine for boiling;
s3, the control module controls the boiled liquid medicine to be filtered, and the filtered liquid medicine is sent into a concentration tank for concentration;
s4, the control module conveys the concentrated liquid medicine to a bagging machine to prepare a traditional Chinese medicine concentrate;
in the step S1, when the bulk drug is delivered to a crusher for crushing, the control module sets the initial rotation speed of the crusher to Va1.
In the step S2, when the powder is boiled, the control module sets the boiling temperature of the boiling machine to be T, and performs ultrasonic vibration during the boiling process, and the control module determines the ultrasonic vibration frequency according to the average particle size of the Chinese medicine particles and the particle size during the boiling process;
in the step S3, when the filtered liquid medicine is concentrated, the control module obtains the evaporation amount of the concentration tank, and determines whether the concentration is completed according to the evaporation amount.
In the preparation method of the obesity traditional Chinese medicine of the embodiment of the invention, in the step S2, when the ultrasonic frequency is determined, the control module sets the ultrasonic vibration frequency corresponding to the average particle size and the preset average particle size in the control module,
wherein the control module is provided with a first preset average particle diameter R1, a second preset average particle diameter R2, a third average particle diameter R3, a first ultrasonic frequency P1, a second ultrasonic frequency P2 and a third ultrasonic frequency P3, wherein R1 is more than R2 and less than R3, P1 is more than P2 and less than P3,
when R is less than or equal to R1, the control module sets the ultrasonic vibration frequency to P1;
when R1 is more than R and less than or equal to R2, the control module sets the ultrasonic vibration frequency to P2;
when R2 is less than R and less than or equal to R3, the control module sets the ultrasonic vibration frequency to P3.
In the preparation method of the obesity traditional Chinese medicine of the embodiment of the invention, in the step S2, when the control module controls the boiling machine to cook, the control module obtains the concentration W of the liquid medicine when the boiling time is up to t0, determines whether the boiling is completed according to the comparison result of the concentration W and the preset concentration W0,
if W is less than W0, the control module judges that the boiling is not finished;
and if W is more than or equal to W0, the control module judges that the boiling is finished.
Specifically, when the control module judges that the boiling is not finished, the control module calculates a concentration difference value delta W between the concentration and a preset concentration, sets delta W=W0-W, selects a corresponding adjusting coefficient to adjust the ultrasonic vibration frequency according to the comparison result of the concentration difference value and the preset concentration difference value,
wherein the control module is provided with a first preset concentration difference value delta W1, a second preset concentration difference value delta W2, a third preset concentration difference value delta W3, a first frequency adjustment coefficient Kp1, a second frequency adjustment coefficient Kp2 and a third frequency adjustment coefficient Kp3, wherein delta W1 is less than delta W2 and less than delta W3, kp1 is less than Kp2 and less than Kp3 is set,
when DeltaW is less than or equal to DeltaW 1, the control module selects a first frequency adjusting coefficient Kp1 to adjust the ultrasonic vibration frequency;
when DeltaW 1 is more than DeltaW and less than or equal to DeltaW 2, the control module selects a second frequency adjusting coefficient Kp2 to adjust the ultrasonic vibration frequency;
when DeltaW 2 is smaller than DeltaW and smaller than DeltaW 3, the control module selects a third frequency adjusting coefficient Kp3 to adjust the ultrasonic vibration frequency;
when the control module selects the ith frequency adjustment coefficient Kpi to adjust the ultrasonic vibration frequency, setting i=1, 2 and 3, and setting the adjusted ultrasonic vibration frequency as Pn ', and setting Pn' =pn×kpi.
In the method for preparing obesity according to the embodiment of the present invention, in the step S2, when the adjustment of the ultrasonic vibration frequency is completed, the control module compares the adjusted ultrasonic frequency Pn' with the maximum ultrasonic frequency Pmax in the control module,
if Pn' > Pmax, the control module judges that the ultrasonic vibration frequency exceeds the standard;
and if Pn' is less than or equal to Pmax, the control module judges that the ultrasonic vibration frequency is qualified.
Specifically, when the control module determines that the ultrasonic vibration frequency exceeds the standard, the control module calculates a frequency difference value delta P between the ultrasonic vibration frequency Pn 'and the maximum ultrasonic frequency Pmax after adjustment, sets delta p=p' -Pmax, selects a corresponding compensation coefficient to compensate the working time of the crusher according to the comparison result of the frequency difference value and the preset frequency difference value,
wherein the control film is provided with a first preset frequency difference value delta P1, a second preset frequency difference value delta P2, a third preset frequency difference value delta P3, a first time length compensation coefficient Kt1, a second time length compensation coefficient Kt2 and a third time length compensation coefficient Kt3, wherein delta P1 is more than delta P2 and less than delta P3, kt1 is more than 1 and less than Kt2 and less than Kt3 and less than 1.5,
when the delta P is less than or equal to delta P1, the control module selects a first time length compensation coefficient Kt1 to adjust the working time length of the crusher;
when delta P1 is smaller than delta P and is smaller than or equal to delta P2, the control module selects a second time length compensation coefficient Kt2 to adjust the working time length of the crusher;
when delta P2 is smaller than delta P and is smaller than or equal to delta P3, the control module selects a third time length compensation coefficient Kt3 to adjust the working time length of the crusher;
when the control module selects the j-th time length compensation coefficient Ktj to adjust the working time length of the crusher, j=1, 2 and 3 are set, the control module sets the working time length of the crusher after compensation to be t', and t=t× Ktj is set, wherein t is the initial working time length of the crusher.
In the preparation method of the obesity traditional Chinese medicine of the embodiment of the invention, in the step S3, when the control module determines whether concentration is completed according to the evaporation amount, the control module compares the evaporation amount Q of the concentration tank with the preset evaporation amount Q0 and determines whether concentration is completed according to the comparison result,
if Q is more than or equal to Q0, the control module judges that concentration is finished;
and if Q is less than Q0, the control module judges that concentration is not finished.
Specifically, when the control module determines that concentration is not completed, the control module calculates an evaporation amount difference delta Q between the evaporation amount Q and a preset evaporation amount Q0, sets delta q=q0-Q, selects a corresponding adjustment coefficient concentration temperature according to a comparison result of the evaporation amount difference and the preset evaporation amount difference, adjusts,
wherein the control module is provided with a first preset evaporation capacity difference value delta Q1, a second preset evaporation capacity difference value delta Q2, a third preset evaporation capacity difference value delta Q3, a first temperature adjustment coefficient X1, a second temperature adjustment coefficient X2 and a third temperature adjustment coefficient X3, wherein delta Q1 is less than delta Q2 and less than delta Q3, X1 is less than X2 and less than X3 is less than 1.2,
when the delta Q is less than or equal to delta Q1, the control module selects a first temperature adjustment coefficient X1 to adjust the concentration temperature;
when delta Q1 is smaller than delta Q and smaller than delta Q2, the control module selects a second temperature regulating coefficient X2 to regulate the concentration temperature;
when delta Q2 is smaller than delta Q and smaller than or equal to delta Q3, the control module selects a third temperature regulating coefficient X3 to regulate the concentration temperature;
when the control module selects the e-th temperature adjustment coefficient Xe to adjust the concentration temperature, e=1, 2,3 is set, and the control module sets the adjusted concentration temperature to Tz ', and sets Tz' =tz×xe.
Specifically, when the liquid medicine is concentrated, the control module obtains the concentration N of the liquid medicine and determines the concentration temperature of the concentration tank according to the comparison result of the concentration and the preset concentration,
wherein the control module is also provided with a first preset concentration N1, a second preset concentration N2, a third preset concentration N3, a first concentration temperature T1, a second concentration temperature T2 and a third concentration temperature T3, wherein N1 is more than N2 and less than N3, T1 is more than T2 and less than T3,
when N is less than or equal to N1, the control module sets the concentration temperature of the concentration tank to be T1;
when N1 is more than N and less than or equal to N2, the control module sets the concentration temperature of the concentration tank to be T2;
when N2 is less than N and less than or equal to N3, the control module sets the concentration temperature of the concentration tank to be T3.
Thus far, the technical solution of the present invention has been described in connection with the preferred embodiments shown in the drawings, but it is easily understood by those skilled in the art that the scope of protection of the present invention is not limited to these specific embodiments. Equivalent modifications and substitutions for related technical features may be made by those skilled in the art without departing from the principles of the present invention, and such modifications and substitutions will be within the scope of the present invention.
The foregoing description is only of the preferred embodiments of the invention and is not intended to limit the invention; various modifications and variations of the present invention will be apparent to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. The traditional Chinese medicine formula for treating obesity is characterized by comprising the following raw materials in parts by mass:
5-8 parts of rose, 10-15 parts of yam slices and 6-10 parts of seaweed, which are respectively dried in an oven at 80 ℃;
4.5-7 parts of astragalus mongholicus, 6-10 parts of ground bone, 3-5 parts of hawthorn, 10-12 parts of rhizoma atractylodis and 5-9 parts of radix salviae miltiorrhizae after being soaked in warm water at 60 ℃.
2. The method for preparing the traditional Chinese medicine for treating obesity according to claim 1, which is characterized by comprising the following steps:
s1, a control module controls the raw material medicines with preset mass parts to be conveyed into a crusher for shearing and crushing to obtain traditional Chinese medicine granules;
s2, the control module controls the smashed medicinal powder to be sent into a boiling machine for boiling;
s3, the control module controls the boiled liquid medicine to be filtered, and the filtered liquid medicine is sent into a concentration tank for concentration;
s4, the control module conveys the concentrated liquid medicine to a bagging machine to prepare a traditional Chinese medicine concentrate;
in the step S1, when the bulk drug is conveyed to a crusher for crushing, the control module sets the initial rotation speed of the crusher to Va1;
in the step S2, when the powder is boiled, the control module sets the boiling temperature of the boiling machine to be T, and performs ultrasonic vibration during the boiling process, and the control module determines the ultrasonic vibration frequency according to the average particle size of the Chinese medicine particles and the particle size during the boiling process;
in the step S3, when the filtered liquid medicine is concentrated, the control module obtains the evaporation amount of the concentration tank, and determines whether the concentration is completed according to the evaporation amount.
3. The method for preparing a traditional Chinese medicine for treating obesity according to claim 2, wherein in the step S2, when determining the ultrasonic frequency, the control module sets the ultrasonic vibration frequency corresponding to the average particle size and the preset average particle size in the control module,
wherein the control module is provided with a first preset average particle diameter R1, a second preset average particle diameter R2, a third average particle diameter R3, a first ultrasonic frequency P1, a second ultrasonic frequency P2 and a third ultrasonic frequency P3, wherein R1 is more than R2 and less than R3, P1 is more than P2 and less than P3,
when R is less than or equal to R1, the control module sets the ultrasonic vibration frequency to P1;
when R1 is more than R and less than or equal to R2, the control module sets the ultrasonic vibration frequency to P2;
when R2 is less than R and less than or equal to R3, the control module sets the ultrasonic vibration frequency to P3.
4. The method for preparing an obesity drug according to claim 3, wherein in the step S2, when the control module controls the decocting machine to perform the decoction, the control module obtains the concentration W of the drug solution when the decoction is performed for a time period of t0, determines whether the decoction is completed according to a comparison result of the concentration W and a preset concentration W0,
if W is less than W0, the control module judges that the boiling is not finished;
and if W is more than or equal to W0, the control module judges that the boiling is finished.
5. The method according to claim 4, wherein when the control module determines that the boiling is not completed, the control module calculates a concentration difference Δw between the concentration and a preset concentration, sets Δw=w0-W, and selects a corresponding adjustment coefficient according to a comparison result of the concentration difference and the preset concentration difference to adjust the ultrasonic vibration frequency, and the control module sets the adjusted ultrasonic vibration frequency as Pn ', and sets Pn' =pn×kpi, wherein Kpi is a frequency adjustment coefficient.
6. The method according to claim 5, wherein in the step S2, when the adjustment of the ultrasonic vibration frequency is completed, the control module compares the adjusted ultrasonic frequency Pn' with a maximum ultrasonic frequency Pmax in the control module,
if Pn' > Pmax, the control module judges that the ultrasonic vibration frequency exceeds the standard;
and if Pn' is less than or equal to Pmax, the control module judges that the ultrasonic vibration frequency is qualified.
7. The method according to claim 6, wherein when the control module determines that the ultrasonic vibration frequency exceeds the standard, the control module calculates a frequency difference Δp between the ultrasonic vibration frequency Pn 'and a maximum ultrasonic frequency Pmax after adjustment, sets Δp=p' -Pmax, selects a corresponding compensation coefficient according to a comparison result of the frequency difference and a preset frequency difference, compensates the working time of the crusher, and sets the working time of the crusher after compensation as t ', sets t' =t Ktj, where t is an initial working time of the crusher, and Ktj is a time compensation coefficient.
8. The method for preparing an obesity drug according to claim 7, wherein in the step S3, when the control module determines whether concentration is completed according to the evaporation amount, the control module compares the evaporation amount Q of the concentration tank with a preset evaporation amount Q0 and determines whether concentration is completed according to the comparison result,
if Q is more than or equal to Q0, the control module judges that concentration is finished;
and if Q is less than Q0, the control module judges that concentration is not finished.
9. The method according to claim 8, wherein the control module calculates an evaporation amount difference Δq between the evaporation amount Q and a preset evaporation amount Q0, sets Δq=q0-Q, and selects a corresponding adjustment coefficient concentration temperature according to a comparison result of the evaporation amount difference and the preset evaporation amount difference to adjust, and sets the adjusted concentration temperature as Tz ', and sets Tz' =tz×xe, wherein Xe is a concentration temperature adjustment coefficient.
10. The method according to claim 9, wherein the control module obtains the concentration N of the medicinal liquid when concentrating the medicinal liquid, and determines the concentration temperature of the concentration tank according to the comparison result of the concentration and the preset concentration,
wherein the control module is also provided with a first preset concentration N1, a second preset concentration N2, a third preset concentration N3, a first concentration temperature T1, a second concentration temperature T2 and a third concentration temperature T3, wherein N1 is more than N2 and less than N3, T1 is more than T2 and less than T3,
when N is less than or equal to N1, the control module sets the concentration temperature of the concentration tank to be T1;
when N1 is more than N and less than or equal to N2, the control module sets the concentration temperature of the concentration tank to be T2;
when N2 is less than N and less than or equal to N3, the control module sets the concentration temperature of the concentration tank to be T3.
CN202210223203.1A 2022-03-07 2022-03-07 Traditional Chinese medicine formula for treating obesity and preparation method thereof Pending CN116763868A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117064956A (en) * 2023-10-18 2023-11-17 康源博创生物科技(北京)有限公司 Pharmaceutical composition with osteoporosis resisting effect and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117064956A (en) * 2023-10-18 2023-11-17 康源博创生物科技(北京)有限公司 Pharmaceutical composition with osteoporosis resisting effect and preparation method thereof

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