CN116723869A - 增强胆固醇的基于线粒体的流动和分解代谢 - Google Patents

增强胆固醇的基于线粒体的流动和分解代谢 Download PDF

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Publication number
CN116723869A
CN116723869A CN202180080530.XA CN202180080530A CN116723869A CN 116723869 A CN116723869 A CN 116723869A CN 202180080530 A CN202180080530 A CN 202180080530A CN 116723869 A CN116723869 A CN 116723869A
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protein
leu
cholesterol
ala
gly
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穆拉德·托珀斯
里森
吉列尔梅·切尔曼·佩尔迪冈·德·奥利维拉
马克·里迪拉
戴维·麦肯齐-刘
加勒特·斯特劳
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Repair Biotechnology Co
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Repair Biotechnology Co
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CN202180080530.XA 2020-12-08 2021-12-08 增强胆固醇的基于线粒体的流动和分解代谢 Pending CN116723869A (zh)

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US202063122886P 2020-12-08 2020-12-08
US63/122,886 2020-12-08
PCT/US2021/062389 WO2022125653A1 (en) 2020-12-08 2021-12-08 Enhancing mitochondrial-based flow and catabolism of cholesterol

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CN116723869A true CN116723869A (zh) 2023-09-08

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US (1) US20240050592A1 (https=)
EP (1) EP4259802A4 (https=)
JP (1) JP2023552800A (https=)
CN (1) CN116723869A (https=)
AU (1) AU2021394760A1 (https=)
CA (1) CA3203461A1 (https=)
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US11612619B2 (en) 2018-11-01 2023-03-28 National Institute Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs), U.S. Government Compostions and methods for enabling cholesterol catabolism in human cells
US12544402B2 (en) 2020-02-28 2026-02-10 Repair Biotechnologies, Inc. Targeted expression of microbial cholesterol catalysis genes reduces excess lipid

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US6903183B1 (en) * 1996-06-07 2005-06-07 Texas Tech University Health Services Center Compositions and methods for regulation of steroidogenesis
CA2349761A1 (en) * 1998-11-06 2000-05-18 Incyte Pharmaceuticals, Inc. Corticosteroid synthesis-associated genes
AU2003253606A1 (en) * 2002-05-20 2003-12-12 Regents Of The University Of California Methods and compositions for regulation and manipulation of steroidogenesis
JP2005531305A (ja) * 2002-06-10 2005-10-20 エヴォテック ニューロサイエンシス ゲゼルシャフト ミット ベシュレンクテル ハフツング ステロイド産生急性調節タンパク質の神経変性疾患に関する診断的および治療的使用
US11612619B2 (en) * 2018-11-01 2023-03-28 National Institute Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs), U.S. Government Compostions and methods for enabling cholesterol catabolism in human cells

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EP4259802A1 (en) 2023-10-18
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US20240050592A1 (en) 2024-02-15
WO2022125653A1 (en) 2022-06-16
CA3203461A1 (en) 2022-06-16

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