CN116635020A - 一种芳香化合物、其制备方法及应用 - Google Patents

一种芳香化合物、其制备方法及应用 Download PDF

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Publication number
CN116635020A
CN116635020A CN202280007535.4A CN202280007535A CN116635020A CN 116635020 A CN116635020 A CN 116635020A CN 202280007535 A CN202280007535 A CN 202280007535A CN 116635020 A CN116635020 A CN 116635020A
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China
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substituted
alkyl
mmol
independently
compound
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Pending
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CN202280007535.4A
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English (en)
Chinese (zh)
Inventor
娄军
陈永凯
张轶涵
郭晓丹
柳力
彭微
容飞
吴伟
王朝东
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Wuhan LL Science and Technology Development Co Ltd
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Wuhan LL Science and Technology Development Co Ltd
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Publication of CN116635020A publication Critical patent/CN116635020A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202280007535.4A 2021-01-27 2022-01-27 一种芳香化合物、其制备方法及应用 Pending CN116635020A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN202110113303 2021-01-27
CN2021101133034 2021-01-27
CN202110638504 2021-06-08
CN2021106385046 2021-06-08
CN202210055268X 2022-01-18
CN202210055268 2022-01-18
PCT/CN2022/074136 WO2022161416A1 (fr) 2021-01-27 2022-01-27 Composé aromatique, son procédé de préparation et son application

Publications (1)

Publication Number Publication Date
CN116635020A true CN116635020A (zh) 2023-08-22

Family

ID=82653024

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280007535.4A Pending CN116635020A (zh) 2021-01-27 2022-01-27 一种芳香化合物、其制备方法及应用

Country Status (3)

Country Link
CN (1) CN116635020A (fr)
TW (1) TW202239748A (fr)
WO (1) WO2022161416A1 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018528159A (ja) * 2015-06-10 2018-09-27 バイエル・ファルマ・アクティエンゲゼルシャフト 芳香族スルホンアミド誘導体
CN114984003A (zh) * 2016-05-03 2022-09-02 拜耳制药股份公司 芳族磺酰胺衍生物
WO2018104307A1 (fr) * 2016-12-09 2018-06-14 Bayer Pharma Aktiengesellschaft Dérivés de sulfonamide aromatiques et leur utilisation en tant qu'anatagon i sts ou des modulateurs allostériques négatifs de p2x4
WO2018104305A1 (fr) * 2016-12-09 2018-06-14 Bayer Pharma Aktiengesellschaft Sulfamoylbenzamides
WO2018210729A1 (fr) * 2017-05-18 2018-11-22 Bayer Pharma Aktiengesellschaft Dérivés de sulfonamide aromatiques utilisés en tant qu'antagonistes ou modulateurs allostériques négatifs du récepteur p2x4
CN111511720A (zh) * 2017-10-29 2020-08-07 拜耳股份公司 用于治疗缺血性中风的芳族磺酰胺衍生物

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Publication number Publication date
TW202239748A (zh) 2022-10-16
WO2022161416A1 (fr) 2022-08-04

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