CN116603002A - Traditional Chinese medicine composition for treating furuncle and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating furuncle and preparation method thereof Download PDF

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CN116603002A
CN116603002A CN202310482238.1A CN202310482238A CN116603002A CN 116603002 A CN116603002 A CN 116603002A CN 202310482238 A CN202310482238 A CN 202310482238A CN 116603002 A CN116603002 A CN 116603002A
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chinese medicine
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furuncle
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马成
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/648Myriapods, e.g. centipedes or millipedes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract

The application discloses a traditional Chinese medicine composition for treating furuncle and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The preparation method comprises the following steps: centipede, kuh-seng and honeysuckle stem; the medicines are mixed according to the corresponding proportion; the prepared medicines are prepared into decoction and powder. The composition has the effects of clearing heat and detoxicating, resolving carbuncles and resolving hard mass, promoting blood circulation and removing obstruction in channels to relieve pain, has obvious curative effect on furuncle, and is not easy to relapse.

Description

Traditional Chinese medicine composition for treating furuncle and preparation method thereof
Technical Field
The application relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating furuncle.
Background
Furuncle, for short, is an acute suppurative disease with rapid onset, easy change and high risk. It is often found on the face and hands and feet. The clinical characteristics are that although the sore shape is small, the root and the foot are hard, the disease state is rapid to change like a spike, and the toxic evil is easy to break away. If not properly treated, furuncles on the face are easy to yellow and life-threatening; furuncle on the hands and feet can damage bones and tendons to affect limb functions. As early as in the theory of Su Wen and Sheng Qi Tong Tian Lun, there is a description of "sorghum Chang, zu Sheng Dading". "surgical Authentic furuncle theory" is: the patient suffering from furuncle is also a rapid surgical disease. The hair is dying immediately, the hair is dying along with the hair, the hair is not dying for three or five days, and the hair is dying for one month and half month. So people have the theory of walking on horses to see furuncle, so that the user can not feel wrong in treating furuncle. The disease is equivalent to Western furuncles, carbuncles, gas gangrene, skin anthrax, acute lymphangitis and the like. Traditional Chinese medicine considers that the toxic heat is mainly caused by fire heat. The occurrence of the traditional Chinese medicine is often related to the thick taste of the paste, pungent and roasted product, unclean skin, mosquito bite, invasion of fire toxin after the penetration and other factors, and the basic pathogenesis is accumulation of fire toxin in the skin and stagnation of qi and blood in channels and collaterals.
The main methods for treating furuncle are antibiotics, traditional Chinese medicine, acupuncture and surgery. Although the antibiotic treatment has a certain effect, the problems of abuse phenomenon, great side effect, high cost and the like exist, and after suppuration, a part of patients need to be cut open for drainage, the treatment period is long, and especially the scar is left on the face. The traditional Chinese medicine has long treatment history, has outstanding clinical effects through internal and external treatment methods, acupuncture and moxibustion and other treatment methods, and most scholars recognize that the disease distinguishes internal heat syndrome and fire toxin accumulation is the main cause, and the clinical treatment mainly has the effects of clearing heat and detoxicating, resolving carbuncles and removing furuncles, promoting blood circulation and removing blood stasis and the like, but has complicated and complicated methods, high cost, weak clinical replicability and easy relapse of most people. Therefore, the medicine for treating furuncle has the advantages of simple and convenient method, definite curative effect, economy, small side effect, difficult recurrence, strong operability and the like.
Disclosure of Invention
Aiming at the defects in the prior art, the application aims to provide a traditional Chinese medicine composition for treating furuncle and a preparation method thereof, and the traditional Chinese medicine composition has the effects of clearing heat and detoxicating, resolving carbuncles and removing furuncles, and activating blood and dissolving stasis, has remarkable effects for treating furuncle, and can effectively and rapidly solve the problem of easy recurrence of furuncle.
The application also aims to provide a preparation method of the traditional Chinese medicine composition for treating furuncle, which is prepared into powder or capsules, and is convenient for patients with recurrent attacks to take for a long time, and removes roots.
In order to achieve the above purpose, the application adopts the following technical scheme:
the first aspect of the application provides a traditional Chinese medicine composition for treating furuncle, which consists of centipede, kuh-seng and honeysuckle stem.
Among the above technical schemes, the more specific technical scheme is: the weight portions of the raw materials are as follows:
1-10 parts of centipede, 3-20 parts of radix sophorae flavescentis and 4-20 parts of honeysuckle stem.
Further, the weight portions of the raw materials are as follows:
2 parts of centipede, 4 parts of kuh-seng and 4 parts of honeysuckle stem.
Furthermore, the traditional Chinese medicine composition for treating furuncle is prepared into decoction for oral administration.
Further, the preparation method of the traditional Chinese medicine composition for treating furuncle comprises the following steps:
(1) the medicines are mixed according to a proportion;
(2) placing the well-matched medicines into a medicine tank, firstly adding 6-8 times of water medicine materials to soak for more than 30 minutes, decocting for 30-40 minutes, filtering out, adding 4-6 times of water to decoct for 30-40 minutes, filtering out, finally adding 2-4 times of water to decoct for 30-40 minutes, filtering out, combining the three filtrates, and collecting medicine soup.
The second aspect of the application provides a traditional Chinese medicine composition for treating furuncle, which comprises the following raw materials in parts by weight:
10 parts of centipede, 20 parts of radix sophorae flavescentis and 20 parts of honeysuckle stem.
Furthermore, the traditional Chinese medicine composition for treating furuncle is prepared into powder or capsules for oral administration.
Further, the preparation method of the traditional Chinese medicine composition for treating furuncle comprises the following steps:
(1) the medicines are mixed according to a proportion;
(2) cleaning and drying the medicines, and performing sterilization treatment;
(3) pulverizing the above materials by pulverizer, sieving with 80-120 mesh sieve to ensure that the powder is dry, loose, uniform and uniform in color;
(4) mixing the above powders, stirring, and packaging in dry glass bottle or capsule.
The third aspect of the application provides the application of the traditional Chinese medicine composition in preparing medicines for treating furuncle.
In mild and early patients, the preparation form of the traditional Chinese medicine composition is preferably decoction.
Patients who are refractory and repeatedly take medicines for a long time, preferably, the traditional Chinese medicine composition is in a capsule or powder form. More preferably, the traditional Chinese medicine composition is in a decoction form.
The common pharmacological effects of the selected drug raw materials in the field are as follows:
scolopendra is dry body of Scolopendra subspinipes spinosus of Centipedae of Centipeda. Pungent taste and warm nature; enter liver meridian. Has the effects of calming endogenous wind and relieving spasm, eliminating toxin and resolving masses, and dredging collaterals and relieving pain, and modern medical researches show that the traditional Chinese medicine has the effects of resisting bacteria and diminishing inflammation, enhancing immunity and dredging the pain. The preparation is mainly used for treating spasmodic tic caused by various reasons; sores and ulcers, scrofula and tuberculosis; chronic arthralgia due to wind-dampness and arthralgia; intractable migraine; the venomous snake bites. The centipede has the effects of resisting bacteria and diminishing inflammation, and modern pharmacological researches prove that the centipede water extract has an inhibiting effect on tuberculosis, staphylococcus, sarcina, pseudomonas aeruginosa, candida albicans and the like; can also inhibit the permeability of capillary vessels, thereby playing a role in detumescence; in addition, scolopendra can be used for enhancing immunity, dredging collaterals and relieving pain.
The kuh-seng is the dry root of kuh-seng of leguminous plants, has bitter taste, cold property, returns to heart, liver, stomach, large intestine and bladder meridian, has the functions of clearing heat, drying dampness, killing parasites and promoting urination, and is used for treating heat dysentery, hematochezia, jaundice and uroschesis, leucorrhea with reddish discharge, swelling and itching of yin, eczema, wet sore, skin itch, mange leprosy and external treatment of trichomonas vaginitis. The matrine has anticancer activity, leukocyte increasing effect, antiallergic effect, immunosuppression effect, diuretic effect, and antibacterial effect.
Honeysuckle stem, chinese medicine name. Also called ficus pumila, salicornia salicifolia, stephania japonica, perennial evergreen winding shrubs, hollow stems, dense young branches and short and soft hairs. Sweet in flavor and cold in nature, enter lung and stomach meridians. Has effects of clearing heat and detoxicating, dispelling pathogenic wind and dredging collaterals. Can be used for treating epidemic febrile disease, skin sore, carbuncle, toxic swelling, dysentery with blood, rheumatic arthralgia, and joint redness, swelling and pain. Modern medical research shows that it has certain inhibiting effect on detumescence and stasis-removing of various arthritis, and also on bacterial infection. The honeysuckle stem has certain therapeutic effect on some infectious hepatitis, can relieve symptoms of hepatitis, and can improve some indexes of liver function injury.
The application has the beneficial effects that:
the application relates to a clinical experience self-fitting prescription, which consists of centipede, kuh-seng and honeysuckle stem; in the prescription, centipede has the functions of counteracting toxic substances and relieving pain, and resolving masses and dredging collaterals and treating sore as a monarch drug; kuh-seng has the effects of clearing heat and drying dampness, removing toxicity and cooling blood, and assisting monarch drug in strengthening the effect of detoxification; honeysuckle stem is sweet in flavor, cold in nature, has the effects of removing toxic substances, clearing heat, dredging collaterals and relieving pain, and has the effects of relieving swelling and resolving masses. The whole prescription has the effects of clearing heat and detoxicating, resolving masses and detumescence, cooling blood and removing obstruction in channels to relieve pain, and has simple prescription and special medicine essence, so that heat toxin stasis and furuncle are dissipated, and the immunity is improved.
The centipede is added in the application, and is caused by the invasion of furuncle due to pathogenic stagnation of fire heat and toxin in the skin, so the centipede is pungent in taste, has strong pungent and scattering property, and has the effects of activating blood circulation to dissipate blood stasis, and counteracting toxic substances and resolving hard mass. Modern medical research shows that the Chinese medicinal composition has the effects of resisting bacteria, diminishing inflammation, enhancing immunity, and relieving pain. The preparation is mainly used for treating spasmodic tic caused by various reasons; sores and ulcers and other sores.
The kuh-seng is added, so that the effects of clearing heat, drying dampness and detoxifying are enhanced, the defect of the effects of centipede on eliminating dampness and clearing heat is overcome, the kuh-seng has the effects of tonifying qi, supporting healthy qi, resisting cancer, increasing leucocyte, resisting allergy, inhibiting immunity, promoting urination and resisting bacteria, and has good sterilization effect on skin diseases.
The honeysuckle stem is added, so that the honeysuckle stem is sweet in taste and cold in nature, and enters lung and stomach meridians. Strengthen the curative effects of clearing heat and detoxicating, dispelling wind and dredging collaterals. It has effects of removing toxic substances, detumescence and removing blood stasis for sore, carbuncle and toxic swelling, and also has certain inhibiting effect for some bacterial infections.
The application has strict prescription, special medicine, obvious and quick curative effect, low price, difficult recurrence and obvious popularization value.
Description of the embodiments
The present application will be further described in detail with reference to the following specific examples
Example 1-Chinese medicinal composition for treating furuncle
The raw materials of the material are as follows:
2 parts of centipede, 4 parts of kuh-seng and 4 parts of honeysuckle stem.
The preparation method comprises the following steps:
(1) the medicines are mixed according to a proportion, and the dosage of 1 part is 5 g;
(2) placing the well-matched medicines into a medicine tank, firstly adding 6-8 times of water for soaking for more than 30 minutes, placing on fire, striking fire to turn on middle fire, decocting for 30-40 minutes, filtering, adding 4-6 times of water for decocting for 30-40 minutes, filtering, finally adding 2-4 times of water for decocting for 30-40 minutes, filtering, combining three filtrates, and collecting medicine soup;
(3) the collected soup is divided into three parts, and is taken after being heated to proper temperature each time, three times a day, and 6 days are continuously taken.
Example 2-Chinese medicinal composition for treating furuncle
The raw materials of the material are as follows:
10 parts of centipede, 20 parts of radix sophorae flavescentis and 20 parts of honeysuckle stem.
The preparation method comprises the following steps:
(1) the medicines are mixed according to a proportion, and the dosage of 1 part is 5 g;
(2) cleaning and drying the medicines, and performing sterilization treatment;
(3) pulverizing the above materials by pulverizer, sieving with 80-120 mesh sieve to ensure that the powder is dry, loose, uniform and uniform in color;
(4) mixing the above powders, stirring, and packaging in dry glass bottle or capsule, wherein 6g crude drug is administered three times per day.
Comparative example 1, which is based on example 1, was performed with little centipede. The preparation method is the same as that of example 1.
Comparative example 2, which is based on example 1, uses less kuh-seng as one of the drugs. The preparation method is the same as that of example 1.
Comparative example 3, which is based on example 1, uses little honeysuckle stem as the drug. The preparation method is the same as that of example 1.
Results of clinical trials
1 clinical data
1.1 general data 150 patients with furuncle at the clinic of Hui nationality hospitals in the group of 6 months in 2013 to 10 months in 2022 are selected, the ages of 23-63 years, and the patients are divided into 5 groups of 30 persons according to clinical study requirements by a random number method.
1.2 diagnostic criteria reference "Chinese clinical dermatology" and "Chinese medical science": it is common in the summer and autumn, which is common to adults in four seasons; is good for facial and hand and foot parts; the first part has a maize-like sore head and is associated with itching; then, the inflammatory swelling and pain is caused, the root and the foot are deeper, hard like nails, swelling and pain are hot, and the reaction is severe; after pus is formed, the furuncle root is broken and removed, and the swelling and pain is gradually eliminated along with the pus going out; general symptoms such as aversion to cold, fever, thirst, constipation, and dark urine are often accompanied; when serious, the patient is easy to get yellow, and the tendons and bones are damaged.
1.3 methods of treatment the first to fourth groups were orally administered with the agents prepared in examples 1 to 3, respectively, and methods of administration. The fifth group is orally administered with cefradine capsule, 0.25-0.5g at a time, 1 time every 6 hours, and 7 days.
1.4 The curative effect judgment standard is used for judging the curative effect according to the traditional Chinese medicine disease diagnosis curative effect standard. And (3) healing: the whole body symptoms disappear, the tumor dissipates, and the wound heals; improvement: the whole body symptoms are relieved or disappeared, and the local induration is not completely dissipated; the method is characterized in that: the local and systemic symptoms are not improved or developed into furuncle, yellow running and injury of bones and muscles.
2. The treatment effect is as follows:
the application is taken for 1 week for treatment, the clinical observation shows that the treatment effect of the example 1 and the treatment effect of the example 2 are prominent, and the follow-up statistics show no obvious discomfort and side effects, and the specific table is shown in the table 1.
As is clear from the above table, the composition of the embodiment 1 and the embodiment 2 is reasonable, has the effects of clearing heat and detoxicating, eliminating carbuncles and resolving hard mass, promoting blood circulation and removing obstruction in channels to relieve pain, has obvious effects on treating furuncle, has no residue and is not easy to relapse.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.

Claims (11)

1. A Chinese medicinal composition for effectively treating furuncle is characterized by comprising centipede, kuh-seng and honeysuckle stem.
2. The traditional Chinese medicine composition for treating furuncle according to claim 1, which is characterized by comprising the following raw materials in parts by weight:
1-10 parts of centipede, 3-20 parts of radix sophorae flavescentis and 4-20 parts of honeysuckle stem.
3. The traditional Chinese medicine composition for treating furuncle according to claim 2, which is characterized by comprising the following raw materials in parts by weight:
2 parts of centipede, 4 parts of kuh-seng and 4 parts of honeysuckle stem.
4. The traditional Chinese medicine composition for treating furuncle according to claim 2, wherein the weight parts of the raw materials are as follows.
5. 10 parts of centipede, 20 parts of radix sophorae flavescentis and 20 parts of honeysuckle stem.
6. The traditional Chinese medicine composition for treating furuncle according to claim 1 or 2 or 3 or 4, wherein: the traditional Chinese medicine composition for treating furuncle is prepared into decoction, powder or capsules for oral administration, and each dose is 5g.
7. The traditional Chinese medicine composition for treating furuncle according to claim 3, wherein the preparation method of the traditional Chinese medicine composition for treating furuncle comprises the following steps:
(1) the medicines are mixed according to a proportion;
(2) placing the well-matched medicines into a medicine tank, firstly adding 6-8 times of water medicine materials to soak for more than 30 minutes, decocting for 30-40 minutes, filtering out, adding 4-6 times of water to decoct for 30-40 minutes, filtering out, finally adding 2-4 times of water to decoct for 30-40 minutes, filtering out, combining the three filtrates, and collecting medicine soup.
8. A method for preparing a medicament for treating furuncle as claimed in claim 2, 3 or 4, wherein said medicament is prepared
The medicine comprises the following steps:
(1) the medicines are mixed according to a proportion;
(2) cleaning and drying the medicines, and performing sterilization treatment;
(3) pulverizing the above materials by pulverizer, sieving with 80-120 mesh sieve to ensure that the powder is dry, loose, uniform and uniform in color;
(4) mixing the above powders, stirring, and packaging in dry glass bottle or capsule.
9. The traditional Chinese medicine composition according to claim 3 and 6, wherein the traditional Chinese medicine composition is in the form of decoction.
10. The traditional Chinese medicine composition according to claim 4 and 7, wherein the traditional Chinese medicine composition is in the form of powder or capsule.
11. Use of a traditional Chinese medicine composition according to any one of claims 1-8 for preparing a medicament for treating furuncle.
CN202310482238.1A 2023-04-29 2023-04-29 Traditional Chinese medicine composition for treating furuncle and preparation method thereof Pending CN116603002A (en)

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