CN116600903A - Liquid injection tool for living body - Google Patents

Abstract

The invention provides a medical liquid injection tool for organisms, which can make the medical liquid finer and spray the medical liquid into a body cavity. The nozzle of the biological medicine liquid injection tool of the invention comprises: a tubular chemical liquid discharge unit (discharge tube (13)) provided at the tip end portion (head portion (12)) of the nozzle and discharging the chemical liquid located in the internal space; and a gas ejection unit (12 f) located in the vicinity of the discharge tube (13) and spraying the chemical liquid discharged from the discharge tube (13) with a mist by ejecting gas. An inflow opening (slit (13 b)) is formed in the discharge tube (13) on the side of the gas discharge portion (12 f), and an outflow opening (slit (13 c)) is formed on the side opposite to the side of the gas discharge portion (12 f). The gas ejection unit (12 f) ejects the gas in a direction intersecting the direction in which the chemical liquid is ejected from the ejection tube (13). The slits (13 b, 13 c) are formed on the extension line of the injection direction of the gas (G) injected by the gas injection part (12 f).

Description

Liquid injection tool for living body

Technical Field

The present invention relates to a medical fluid injection device for living body for spraying a medical fluid onto an affected part of a living body.

Background

In general, treatment or therapy in a living body is performed by: the trocar is passed through a hole formed in the abdomen or the like, and the nozzle is passed through the inside of the trocar to introduce the chemical solution into the body cavity.

Patent document 1 discloses the following technique: even in a state where the placement of the nozzle is restricted by the trocar, the chemical solution can be ejected to a wide area by the nozzle.

The biological chemical injection tool described in patent document 1 (in this document, a biological tissue adhesive applicator) can spray a plurality of chemical solutions and a gas that mixes these chemical solutions obliquely with respect to the axial direction of the nozzle. In this way, when the chemical liquid is sprayed obliquely to the axial direction of the nozzle, the chemical liquid can be sprayed over a wide range by rotating the nozzle around the axial direction.

Prior art literature

Patent literature

Patent document 1: japanese patent laid-open No. 2013-74988

Disclosure of Invention

Technical problem to be solved by the invention

In the biological drug solution injection tool disclosed in patent document 1, distal end portions of both the gas ejection path and the drug solution flow path are formed obliquely with respect to the axial direction of the nozzle, thereby spraying the drug solution and the gas.

In this biological fluid injection tool, when a gas is supplied to the medical fluid at a high pressure (for example, 0.1 MPa), it is necessary to prevent the sheet such as the tissue adhesive sheet to be sprayed from being displaced by the wind pressure.

When the supply pressure of the gas is reduced (for example, 0.07 MPa) to prevent this positional shift, there is room for improvement in that the gas is used to reduce the particle size of the chemical solution, so that the chemical solutions can be easily mixed and effectively applied to the leeward.

The present invention has been made in view of the above-described problems, and an object thereof is to provide a medical fluid injection device for living body, which can be atomized and sprayed into a body cavity.

Means for solving the technical problems

The biological drug solution injection tool of the present invention is characterized by comprising: a main body portion; and a nozzle extending from the main body, the nozzle including: a tubular chemical liquid discharge portion provided at a distal end portion of the nozzle and discharging chemical liquid located in the internal space; and a gas ejection portion located in the vicinity of the chemical liquid ejection portion, the chemical liquid being sprayed in a mist form by ejecting gas onto the chemical liquid ejected from the chemical liquid ejection portion, an inflow opening being formed on a peripheral wall of the chemical liquid ejection portion on a side of the gas ejection portion, and an outflow opening being formed on a side opposite to the side of the gas ejection portion, the gas ejection portion ejecting gas in a direction intersecting with an ejection direction of the chemical liquid ejected from the chemical liquid ejection portion, the inflow opening and the outflow opening being formed on an extension line of the ejection direction of the gas ejected through the gas ejection portion.

ADVANTAGEOUS EFFECTS OF INVENTION

According to the present invention, a medical fluid injection device for living body, which can be atomized and sprayed into a body cavity, can be provided.

Drawings

Fig. 1 is a perspective view showing a living tissue adhesive applicator and peripheral devices according to the present embodiment.

Fig. 2 is an enlarged perspective view showing a head portion located at a front end portion of the nozzle of fig. 1.

Fig. 3 is a cross-sectional view showing a front end portion of the nozzle in a vertical section through a central axis of the discharge pipe and the gas discharge portion.

Fig. 4 is a front view of the head.

Fig. 5 is a graph showing wind force at each air pressure of the feed gas with respect to the comparative example and the embodiment.

Fig. 6 is a graph showing the particle sizes of the spray chemicals of the comparative example and the example.

Fig. 7 is a diagram showing a head according to a modification example, and is a cross-sectional view showing a tip portion of a nozzle in a vertical cross-section through a central axis of a discharge pipe and a gas discharge portion.

Detailed Description

Hereinafter, embodiments of the biological fluid injection tool according to the present invention will be described with reference to the drawings.

The embodiments described below are merely examples for facilitating understanding of the present invention, and do not limit the present invention. That is, the shape, size, arrangement, etc. of the components described below can be changed or modified without departing from the gist of the present invention, and the present invention naturally includes equivalents thereof.

In all the drawings, the same constituent elements are denoted by the same reference numerals, and overlapping description is omitted as appropriate. In the following, the side from which the drug solution is discharged (the side away from the operator) of the biological drug solution injection tool is referred to as the front side or the distal side, and the opposite side is referred to as the rear side or the proximal side, and is also referred to as the front side or the proximal side, respectively.

Summary of the invention

First, an outline of the present invention will be described mainly with reference to fig. 1 to 3.

Fig. 1 is a perspective view showing a living tissue adhesive applicator 1 and peripheral devices thereof according to the present embodiment. Fig. 2 is an enlarged perspective view showing the head 12 positioned at the front end of the nozzle X in fig. 1, and fig. 3 is a cross-sectional view showing the front end of the nozzle X in a vertical section through the central axes of the discharge pipe 13 and the gas discharge portion 12f.

As shown in fig. 1, the biological chemical solution injection device (biological tissue adhesive application device 1) includes a main body 2 and a nozzle X extending from the main body 2.

The nozzle X includes: a tubular chemical liquid discharge portion (discharge tube 13) provided at a distal end portion (head portion 12) of the nozzle X and discharging the chemical liquid 10 located in the internal space; and a gas ejection portion 12f located in the vicinity of the discharge tube 13, for ejecting gas (gas feed gas G) to the chemical solution 10 discharged from the discharge tube 13, thereby spraying the chemical solution 10 in a mist form.

An inflow opening (slit 13 b) is formed in the peripheral wall 13a of the discharge tube 13 on the side of the gas discharge portion 12f, and an outflow opening (slit 13 c) is formed on the side opposite to the side of the gas discharge portion 12f.

The gas ejection unit 12f ejects the gas G in a direction intersecting the ejection direction of the chemical solution 10 ejected from the ejection tube 13.

The slits 13b and 13c are formed on an extension line of the injection direction in which the gas injection unit 12f injects the gas G.

In the discharge tube 13 according to the present embodiment, the inlet opening through which the gas feed gas G flows in is described as the slit 13b, and the outlet opening through which the gas feed gas G flows out is described as the slit 13 c.

That is, the "inflow opening portion" and the "outflow opening portion" in the discharge tube 13 may be such that the gas supply G can be introduced into the medicine liquid discharge portion (discharge tube 13) to divide the medicine liquid 10. Therefore, the "inflow opening" and the "outflow opening" are not limited to the slits 13b and 13c formed in long dimensions, and may be circular holes or lattice-shaped holes.

The plurality of these may be provided, or a mesh-like member may be bonded to the distal end portion of the chemical liquid discharge portion (discharge tube 13).

The following structure will be described: the discharge pipe 13 extends parallel to the extending direction of the nozzle X, and the gas discharge portion 12f extends in a direction intersecting the extending direction of the discharge pipe 13 to discharge the gas G to the chemical solution 10 discharged from the discharge pipe 13.

However, the present invention is not limited to this configuration, and the opposite configuration (that is, the configuration in which the gas discharge portion 12f extends parallel to the extending direction of the nozzle X and the discharge pipe 13 extends in a direction intersecting the extending direction of the gas discharge portion 12 f) may be adopted.

According to the above configuration, the chemical solution 10 supplied to the chemical solution discharge pipe 13 can be atomized and sprayed by the configuration in which the gas supply G is injected so as to pass through the inflow opening (slit 13 b) and the outflow opening (slit 13 c) formed in the chemical solution discharge portion (discharge pipe 13).

< concerning the overall structure >)

The overall structure of a living tissue adhesive applicator 1 and its peripheral devices, which is a living body liquid injection device according to the present invention, will be described mainly with reference to fig. 1 and 2.

The biological chemical solution injection device (biological tissue adhesive applicator 1) according to the present invention is a device for injecting (applying/spraying) a chemical solution into a body. The chemical solution 10 (see fig. 3) to be injected in the biological chemical solution injection tool according to the present invention may be one type, or two or more types of chemical solutions 10 may be sprayed in the biological tissue adhesive application tool 1 according to the present embodiment. The living tissue adhesive applicator 1 has a function of spraying and mixing a plurality of chemical solutions 10 to be described later at the discharge site, and applying the mixture as an adhesive to organs and the like in a living body.

The living tissue adhesive applicator 1 includes a main body 2 having a space 2s therein, and a nozzle X communicating with the space 2s of the main body 2 and extending distally.

The nozzle X includes an extension portion 11 which communicates with the space 2s inside the main body 2 and extends from the front end side of the main body 2, and a head portion 12 which is attached to the front end of the extension portion 11.

A syringe attachment port 2d is provided at a proximal end portion of the main body 2 so as to protrude toward the proximal end. The chemical solution 10 is supplied from the syringe 17 attached to the syringe attachment port 2d and the plunger 7 to the discharge tube 13 through the body 2.

The main body 2 is filled with the gas G (see fig. 3) through the gas injection portion 2G. The gas supply gas G filled in the main body 2 is supplied to the gas discharge portion 12f.

The main body 2 is provided with a gas injection portion 2G for injecting a gas G (see fig. 3) into the space 2s therein. Specifically, the gas injection portion 2g is formed at a projection of a portion formed on the main body portion 2 that projects upward and rearward (proximal side) obliquely.

The gas discharge portion 12f, which will be described later in detail, discharges the gas G supplied from the gas injection portion 2G into the space 2s inside the main body 2, and mixes the chemical solution 10 discharged from the discharge tube 13 as a mist spray.

An air supply hose 31 for introducing an air supply gas G for spraying the chemical solution 10 into the main body 2 is connected to the biological tissue adhesive applicator 1. The air supply hose 31 is connected to the regulator 30 for regulating the amount of the air supply gas G, and is connected to the main body 2 via the air filter 9.

Specifically, the air supply hose 31 is connected to the regulator 30 by a connector 31a provided on the base end side, and is connected to the connection port 9a of the air filter 9 by a connector 31b provided on the tip end side. The air filter 9 is passed through the feed gas G supplied from the regulator 30 to remove dust and foreign bacteria from the feed gas G.

The gas supply gas G is introduced from the regulator 30 through the gas supply hose 31, the air filter 9, and the gas injection portion 2G, and fills the space 2s inside the main body 2.

Further, two plungers 7 and syringes 17 for introducing different chemical solutions into the main body 2 (more specifically, hoses (not shown) that are positioned in the main body 2 and connected to the discharge tube 13) through the syringe mounting ports 2d are mounted on the main body 2.

Specifically, at both side end portions of the rear surface of the main body 2, two portions protrude rearward, and a syringe attachment port 2d as a chemical liquid injection portion is formed at the rear end of these portions. The two syringe mounting ports 2d are connected to syringes 17, respectively. The chemical solutions 10 respectively filled in the two syringes 17 are pushed into the syringes 17 by the plungers 7, and are supplied to the discharge tube 13 through the syringe mounting ports 2d via a hose, not shown, in the main body 2.

The living tissue adhesive applicator 1 is provided with a plunger holder 8 for simultaneously pressing the two plungers 7 against the syringe 17. The plunger holder 8 is formed in a size that can abut against the base end sides of the two plungers 7.

The extension 11 of the nozzle X is provided to ensure a length for disposing the head 12 attached to the distal end of the extension 11 in the body cavity. For example, the living tissue adhesive applicator 1 is used in a thoracoscopic operation.

For example, when an operation is performed by an EAS (endoscope assisted surgery: endoscope-assisted operation) by inserting a trocar (not shown), it is necessary to apply the chemical solution 10 to the insertion site of the trocar. In this case, since the nozzle X includes the extension portion 11, the nozzle X can be extended in the axial direction, and the reachable position of the head 12, which is the portion where the chemical 10 is sprayed, can be extended according to the application position of the chemical 10.

Structure related to head circumference

Next, the head 12 and the structure around the head 12 will be described mainly with reference to fig. 4, in addition to fig. 1 to 3. Fig. 4 is a front view of the head 12.

As shown in fig. 2 and 3, the head 12 according to the present embodiment includes a head main body 12b, two tubular discharge pipes 13, and two gas discharge portions 12f located in the vicinity of the discharge pipes 13 and injecting the gas G into the chemical solution 10 discharged from the discharge pipes 13.

A fitting portion 12h to be fitted to the front end of the extension 11 is formed at the rear end of the head body 12 b. The fitting portion 12h has an outer surface smaller in diameter than the other portions of the head main body 12b, and is fitted in a state of being opposed to the inner surface of the extension portion 11.

[ discharge tube ]

The discharge pipe 13 extends distally from the head main body 12 b. The chemical solution 10 is sprayed in a mist form by the gas-supplying gas G injected from the gas-injecting section 12f.

A distal end portion of a chemical flow tube, not shown, is connected to a proximal end portion of the discharge tube 13, and the chemical flow tube communicates with the syringe attachment port 2d. Two kinds of chemical solutions to be mixed are discharged from the two discharge pipes 13.

In the present embodiment, one of the discharge pipes 13 discharges a chemical solution containing fibrinogen or the like. The other of the discharge pipes 13 is configured to circulate a chemical solution containing thrombin or the like, which acts on fibrinogen or the like to function as a binder.

A surrounding portion 13d formed around the entire circumference is formed on the liquid medicine discharge portion (discharge tube 13) on the end side (the base end side on the head main body 12b side) of the inflow opening portion (slit 13 b) and the outflow opening portion (slit 13 c).

That is, the discharge tube 13 according to the present embodiment has a portion (a portion having a circular cross section) that does not intersect with the slits 13b and 13c in the circumferential direction.

According to the above configuration, by forming the surrounding portion 13d, the decrease in rigidity of the chemical liquid discharge portion (discharge tube 13) due to the inflow opening (slit 13 b) and the outflow opening (slit 13 c) can be suppressed.

As shown in fig. 4, the opening width W2 on the outer peripheral side of the inflow opening (slit 13 b) is wider than the opening width W1 on the inner peripheral side.

Here, the "width" refers to a length in a direction orthogonal to the ejection direction of the gas ejection portion 12f when the head 12 of the nozzle X is viewed from the axial direction (the direction shown in fig. 4). The outer peripheral side and the inner peripheral side of the inflow opening have the same meaning as the outer peripheral side and the inner peripheral side of the discharge tube 13.

According to the above configuration, the opening width W2 of the inflow opening (slit 13 b) on the outer peripheral side is wider than the opening width W1 of the inner peripheral side, so that the flow rate of the gas G introduced into the discharge tube 13 can be increased while the gas G is introduced into the discharge tube 13 over a wide range. Therefore, the chemical solution 10 supplied to the inside of the discharge tube 13 is sheared by the gas supply G, and is easily atomized.

As shown in fig. 4, the opening width W2 of the inflow opening (slit 13 b) on the outer peripheral side is wider than the flow path diameter D of the gas discharge portion 12f.

When the gas supply gas G injected from the gas injection unit 12f is discharged from the gas injection unit 12f, the spray area of the gas supply gas G becomes wider as it is separated from the gas injection unit 12f.

According to the above configuration, the opening width W2 of the slit 13b is wider than the flow path diameter D of the gas discharge portion 12f, so that the gas G discharged from the gas discharge portion 12f and diffused can be taken in widely from the slit 13 b.

Conversely, the channel diameter D of the gas discharge portion 12f is formed smaller than the opening width W2 on the outer peripheral side of the slit 13 b. As described above, the flow path diameter D is narrowed, so that the flow path area of the gas discharge portion 12f is reduced, and the pressure loss due to contact with the wall surface of the gas discharge portion 12f can reduce the wind pressure of the gas supply gas G supplied from the gas discharge portion 12f and increase the wind speed. Therefore, the occurrence of variation in the spray area of the chemical solution 10 can be suppressed.

The opening width W1 of the inflow opening (slit 13 b) on the inner peripheral side is smaller than the flow path diameter D of the gas discharge portion 12f.

According to the above configuration, the flow rate of the gas supply G is increased to take the gas supply G into the discharge tube 13, and the chemical solution 10 supplied into the discharge tube 13 is sheared to be easily atomized.

The opening width W4 of the outflow opening (slit 13 c) on the outer peripheral side is wider than the opening width W3 on the inner peripheral side.

The liquid medicine 10 flowing into the discharge tube 13 is discharged to the outside through the outflow opening (slit 13 c) having the opening width W4 on the outer peripheral side wider than the opening width W3 on the inner peripheral side, whereby the atomized liquid medicine can be discharged.

Conversely, the opening width W3 of the slit 13c on the inner peripheral side is narrower than the opening width W4 of the slit 13b on the outer peripheral side. With this configuration, the liquid medicine 10 before atomization can be prevented from dropping downward through the opening width W3.

At least one of the inflow opening (slit 13 b) and the outflow opening (slit 13 c) is formed in a slit shape and is formed long in the extending direction of the chemical liquid discharge portion (discharge tube 13).

In the present embodiment, as described above, the inflow opening and the outflow opening are both formed in a slit shape. However, only one of them may be a circular hole or a rectangular hole instead of the slit-like shape.

As described above, if at least one of the inflow opening and the outflow opening is a slit 13b or 13c extending parallel to the extending direction of the discharge tube 13 in the flow path direction of the chemical solution 10, it is preferable from the viewpoint that the chemical solution 10 can be divided over a wide range in the flow path direction by passing the gas G through the slit 13b or 13c even in the chemical solution 10 having a high flow rate.

As shown in fig. 2, when the outer surface of the discharge tube 13 is viewed in the radial direction, the bottoms of the edge surfaces on the proximal sides of the slits 13b and 13c are formed in an arc shape. That is, the slits 13b and 13c have circular arc-shaped edge portions.

By forming the slit 13b in this manner, the gas-sending gas G injected from the gas-injecting section 12f is easily received inside the discharge pipe 13.

The bottoms of the slits 13b and 13c are formed so as to be widely opened toward the outer peripheral side. By configuring the slits 13b and 13c in this manner, the gas G flows in more easily even in the axial direction of the discharge tube 13, and expands easily when flowing out.

As shown in fig. 3, the chemical liquid discharge portion (discharge tube 13) protrudes to extend further toward the distal end side than the gas discharge portion 12f.

The discharge opening 12m of the gas discharge portion 12f is formed obliquely with respect to a virtual plane orthogonal to the extending direction of the discharge tube 13 so as to protrude toward the tip end side of the discharge tube 13 as it is separated from the discharge tube 13 in the radial direction.

In other words, the surface on which the discharge opening 12m is formed (in the present embodiment, the orthogonal surface 12n formed so as to be orthogonal to the discharge direction of the gas feed G) is formed so as to protrude toward the tip end side of the discharge tube 13 as it moves away from the discharge tube 13 in the radial direction with respect to a virtual plane orthogonal to the extending direction of the discharge tube 13.

In this way, the orthogonal surface 12n is formed so as to be inclined with respect to the virtual plane, and the upper end of the discharge opening 12m is positioned closer to the discharge pipe 13 than the front end opening diameter of the discharge pipe 13.

According to the above configuration, the discharge opening 12m of the gas discharge portion 12f protrudes toward the front end side of the discharge tube 13, so that the flow rate of the supplied gas G to the discharge tube 13 can be easily maintained at a high level.

The discharge tube 13 according to the present embodiment is separate from a chemical flow tube, not shown, passing through the body 2, but the present invention is not limited to this configuration and may be integrally formed.

The direction in which the discharge tube 13 is extended as the discharge direction of the chemical solution 10 is not necessarily parallel to the axial direction of the nozzle X, as long as the chemical solution 10 can be sprayed in the direction intersecting the axial direction of the nozzle X.

[ gas discharge portion ]

The gas discharge portion 12f is a portion for discharging the gas G to be supplied from the gas injection portion 2G into the space 2s in the body portion 2 at the distal end portion of the head portion 12.

The gas ejection portion 12f according to the present embodiment is provided with two through holes extending so as to face the discharge points of the chemical solution 10 discharged through the two discharge tubes 13, respectively. Specifically, the gas discharge portion 12f extends obliquely downward toward the distal end side so as to intersect the axial direction of the nozzle X (and the discharge tube 13).

Since the discharge tube 13 and the gas discharge portion 12f each extend in such an orientation, the direction of discharge of the gas supply G can be oriented by rotating the living tissue adhesive applicator 1 around the axis of the nozzle X, and thus the direction of spraying of the chemical solution 10 can be adjusted. Hereinafter, the discharge direction refers to a vector directed to the distal end side with reference to the gas discharge portion 12f.

Further, if the spraying direction of the chemical solution 10 is not required to be adjusted by the rotation of the living tissue adhesive applicator 1, the gas discharge portion 12f may be extended parallel to the extending direction of the nozzle X, and the discharge tube 13 may be extended in a direction intersecting the extending direction of the gas discharge portion 12f, as described above.

As shown in fig. 3, the discharge opening 12m of the gas discharge portion 12f is formed on a surface (orthogonal surface 12 n) orthogonal to the discharge direction of the gas supply G.

According to the above configuration, the gas supply gas G is easily injected from the injection opening 12m at the same timing symmetrically with respect to the central axis of the gas injection unit 12f, and the chemical solution 10 induced while being sheared by the gas supply gas G is easily uniformly sprayed.

The opening area of the gas ejection portion 12f is smaller than the opening area of the chemical liquid ejection portion (ejection tube 13).

The "opening area" refers to the area of the opening on the plane where the opening is formed. That is, the opening area of the gas discharge portion 12f is an area of an opening in the orthogonal surface 12n extending in a direction orthogonal to the discharge direction of the gas supply gas G. The opening area of the discharge tube 13 is the area of an opening (an opening other than the slit 13b and the slit 13c, in the present embodiment, a circular portion shown in fig. 4) on the front end surface of the discharge tube 13.

According to the above configuration, since the opening area of the gas discharge portion 12f is smaller than the opening area of the chemical liquid discharge portion (discharge tube 13), the pressure loss (energy loss) of the feed gas G can be increased, the wind force can be reduced, and the wind speed can be increased. By spraying and supplying such a gas G to the chemical solution 10, the chemical solution 10 can be promoted to be formed into a fine mist.

The gas discharge portion 12f has a flow path diameter of 0.3mm or more and 0.6mm or less.

In this way, the flow path diameter of the gas discharge portion 12f is 0.3mm or more and 0.6mm or less, whereby the discharge amount of the gas feed G can be ensured, and the flow rate can be increased, so that the particles of the chemical solution 10 to which the gas feed G is injected can be thinned.

[ eave portion ]

The head 12 further includes an edge 12i at its distal end through the gas discharge portion 12f, and the edge 12i is provided at a position opposite to the position where the discharge pipe 13 is provided.

The eave portion 12i is provided so as to cover the gas discharge portion 12f and the distal end of the discharge tube 13, and is formed so as to protrude further toward the distal end side than the distal end of the discharge tube 13 with reference to the discharge direction of the chemical solution 10. In particular, the eave 12i is formed in a gentle pointed shape.

Specifically, the eave 12i is formed as follows: the central portion in the width direction (in the direction in which the two discharge tubes 13 are aligned in parallel in the present embodiment) protrudes most toward the distal end side, and the amount of protruding from the head main body 12b decreases as it goes toward both sides in the width direction.

More specifically, the brim 12i protrudes from the head main body 12b by a length of 2 times or more the length of the discharge pipe 13 protruding from the head main body 12 b.

The eave portion 12i thus formed functions as a partition wall that separates the gas discharge portion 12f and the discharge pipe 13 from the surrounding environment. Therefore, the eave portion 12i can suppress the influence of the supplied gas G discharged from the gas discharge portion 12f from the surrounding environment, and can maintain the flow-straightening property of the spray of the chemical solution 10.

Further, by the eave portion 12i, it is possible to suppress clogging of the gas ejection portion 12f or the discharge tube 13 due to body fluid or the like adhering to the discharge tube 13 for discharging the chemical solution 10 by contact with an organ or the like. Further, by forming the brim 12i into a pointed shape, the nozzle X is easily inserted from the head 12 into a trocar, not shown.

< concerning spray results >)

Next, a spray result (example) of the chemical solution 10 by the living tissue adhesive applicator 1 according to the present embodiment and a spray result (comparative example) of the chemical solution 10 by a conventional living tissue adhesive applicator not shown will be described mainly with reference to fig. 5 and 6.

Fig. 5 is a graph showing the wind force for each air pressure of the gas G for the comparative example and the example, and fig. 6 is a graph showing the particle size of the spray chemical for the comparative example and the example.

The comparative example shows a living tissue adhesive applicator, not shown, in which a slit is not formed in the discharge tube and the gas discharge portion does not protrude from the head main body 12 b.

The wind force shown in fig. 5 is a load measured when the gas supply gas G is vertically injected from the gas injection unit 12f to the measuring instrument disposed at a position 5cm away from the gas injection unit 12f.

The detailed values shown in the graph of fig. 5 are shown in table 1.

TABLE 1

As shown in fig. 5 and table 1, in the example of the biological tissue adhesive applicator 1, the wind power can be suppressed to about 0.5 to about 0.6 times that of the comparative example.

In the spray test shown in fig. 6, in the example, the chemical solution 10 having fine particle size was applied to the target surface even when the air pressure of the feed gas G injected from the gas injection unit 12f was as low as 0.07MPa, compared to the comparative example.

< modification >

In the head 12 of the above embodiment, the slit 13b and the slit 13c are formed to have the same length in the axial direction of the discharge tube 13, but the present invention is not limited to this configuration.

Next, the head 23 according to the modification will be described mainly with reference to fig. 7. Fig. 7 is a diagram showing the head 23 according to a modification, and is a cross-sectional view showing the tip of the nozzle X in a vertical section through the central axes of the discharge pipe 23 and the gas discharge portion 12f.

The slit 23c as the outflow opening according to this example is formed to have a shorter length than the slit 13c as the inflow opening, and a base end portion of the slit 23c is provided on an extension line connecting a lower end of the gas discharge portion 12f and a base end of the slit 13 c.

That is, the slit 23c is formed on the extension line of the gas supply G that is injected from the gas injection portion 12f and passes through the slit 13 c.

By forming the discharge pipe 23 in this manner, the ratio of the flow of the chemical solution 10 sheared by the gas feed G passing through the slit 13b to the flow of the chemical solution 10 that has not been sheared out of the slit 23c can be increased. With this structure, the liquid droplets of the chemical solution 10 before atomization can be suppressed from dropping.

The biological tissue adhesive applicator 1 according to the present embodiment includes chemical flow passages formed in the two discharge tubes 13.

However, the biological fluid injection tool according to the present invention is not limited to this configuration, and may have a larger number of fluid flow paths, or may be one. Similarly, the number of the gas discharge units 12f is not limited to two, and may be more than two, or may be one.

In the above embodiment, the configuration in which the gas supply G is sprayed in parallel from the two gas discharge portions 12f is described. Even in this structure, the diameter of the discharge pipe 13 is small and the cross-sectional area of the chemical solution 10 passing through the discharge pipe 13 is sufficiently small, so that the two types of chemical solutions 10 can be properly mixed.

However, the present invention is not limited to this structure, and may be structured as follows: in order to promote mixing of the two chemical solutions 10, the two gas ejection portions 12f extend in directions intersecting each other so that the ejection points of the gas-feed gas G ejected from the two gas ejection portions 12f intersect. In this case, the discharge pipe 13 and the inflow opening and the outflow opening formed in the discharge pipe 13 may be provided at the injection site of the supplied gas.

The above embodiment includes the following technical ideas.

(1)

A biological liquid injection tool is characterized by comprising:

a main body portion; a kind of electronic device with high-pressure air-conditioning system

A nozzle extending from the main body portion,

the nozzle is provided with:

a tubular chemical liquid discharge portion provided at a distal end portion of the nozzle and configured to discharge the chemical liquid in the internal space; a kind of electronic device with high-pressure air-conditioning system

A gas spraying part located near the chemical liquid spraying part, spraying the chemical liquid in mist form by spraying gas on the chemical liquid sprayed from the chemical liquid spraying part,

an inflow opening is formed in the peripheral wall of the chemical liquid discharge portion on the gas discharge portion side, and an outflow opening is formed on the opposite side to the gas discharge portion side,

the gas spraying part sprays the gas in a direction crossing the spraying direction of the liquid medicine sprayed from the liquid medicine spraying part,

the inflow opening portion and the outflow opening portion are formed on an extension line of the injection direction of the gas injected by the gas injection portion.

(2)

The biological chemical injection device according to (1), wherein,

the liquid medicine discharge portion has a surrounding portion formed around the entire circumference on an end side of the inflow opening and the outflow opening.

(3)

The biological chemical solution injection tool according to (1) or (2), wherein,

the opening width of the inflow opening on the outer peripheral side is wider than the opening width of the inflow opening on the inner peripheral side.

(4)

The biological chemical injection device according to (3), wherein,

the opening width of the inflow opening on the outer peripheral side is wider than the flow path diameter of the gas ejection section.

(5)

The biological chemical solution injection tool according to (3) or (4), wherein,

the opening width of the inflow opening on the inner peripheral side is smaller than the flow path diameter of the gas discharge portion.

(6)

The biological chemical injection device according to any one of (1) to (5), wherein,

the opening width of the outflow opening portion on the outer peripheral side is wider than the opening width of the outflow opening portion on the inner peripheral side.

(7)

The biological chemical injection device according to any one of (1) to (6), wherein,

at least one of the inflow opening and the outflow opening is formed in a slit shape and is formed to be long in the extending direction of the chemical liquid discharge portion.

(8)

The biological chemical injection device according to any one of (1) to (7), wherein,

the opening area of the gas ejection portion is smaller than the opening area of the chemical liquid ejection portion.

(9)

The biological chemical injection device according to any one of (1) to (8), wherein,

the liquid medicine discharge portion extends and protrudes toward the distal end side than the gas discharge portion,

the discharge opening of the gas discharge portion is formed so as to be inclined with respect to a virtual plane orthogonal to the extending direction of the chemical liquid discharge portion so as to protrude toward the distal end side of the chemical liquid discharge portion as it is separated from the chemical liquid discharge portion.

(10)

The biological chemical injection device according to (9), wherein,

the ejection opening is formed on a surface orthogonal to the ejection direction of the gas.

(11)

The biological chemical injection device according to any one of (1) to (10), wherein,

the gas discharge portion has a flow path diameter of 0.3mm or more and 0.6mm or less.

Industrial applicability

According to the present invention, a medical fluid injection device for living body, which can be atomized and sprayed into a body cavity, can be provided.

Description of the reference numerals

1-biological tissue adhesive applicator (biological chemical injection tool), 2-body part, 2 d-syringe mounting port, 2G-gas injection part, 2 s-space, 7-plunger, 8-plunger holder, 9-air filter, 9 a-connection port, 10-chemical, 11-extension, 12-head (tip), 12 b-head body, 12 f-gas ejection part, 12 h-fitting part, 12 i-eaves, 12 m-ejection opening, 12 n-orthogonal face, 13-ejection tube (chemical ejection part), 13 a-peripheral wall, 13 b-slit (inflow opening), 13 c-slit (outflow opening), 13 d-surrounding part, 17-syringe, 22-head (tip), 23-ejection tube, 23 c-slit (outflow opening), 30-regulator, 31-air supply hose, 31a, 31 b-connector, G-gas (gas), X-nozzle.

Claims (11)

1. A biological liquid injection tool is characterized by comprising:

a main body portion; a kind of electronic device with high-pressure air-conditioning system

A nozzle extending from the main body portion,

the nozzle is provided with:

a tubular chemical liquid discharge portion provided at a distal end portion of the nozzle and discharging chemical liquid located in the internal space; a kind of electronic device with high-pressure air-conditioning system

A gas spraying part located near the chemical liquid spraying part, spraying the chemical liquid in mist form by spraying gas on the chemical liquid sprayed from the chemical liquid spraying part,

an inflow opening is formed in the peripheral wall of the chemical liquid discharge portion on the gas discharge portion side, and an outflow opening is formed on the opposite side to the gas discharge portion side,

the gas spraying part sprays the gas in a direction crossing the spraying direction of the liquid medicine sprayed from the liquid medicine spraying part,

the inflow opening portion and the outflow opening portion are formed on an extension line of the injection direction of the gas injected by the gas injection portion.

2. The biological chemical injection device according to claim 1, wherein,

the liquid medicine discharge portion has a surrounding portion formed around the entire circumference on an end side of the inflow opening and the outflow opening.

3. The biological fluid injection tool according to claim 1 or 2, wherein,

the opening width of the inflow opening on the outer peripheral side is wider than the opening width of the inflow opening on the inner peripheral side.

4. The medical fluid injection device for living body according to claim 3, wherein,

the opening width of the inflow opening on the outer peripheral side is wider than the flow path diameter of the gas ejection section.

5. The biological chemical injection device according to claim 3 or 4, wherein,

the opening width of the inflow opening on the inner peripheral side is smaller than the flow path diameter of the gas discharge portion.

6. The biological fluid injection device according to any one of claims 1 to 5, wherein,

the opening width of the outflow opening portion on the outer peripheral side is wider than the opening width of the outflow opening portion on the inner peripheral side.

7. The biological fluid injection tool according to any one of claims 1 to 6, wherein,

at least one of the inflow opening and the outflow opening is formed in a slit shape and is formed to be long in the extending direction of the chemical liquid discharge portion.

8. The biological fluid injection tool according to any one of claims 1 to 7, wherein,

the opening area of the gas ejection portion is smaller than the opening area of the chemical liquid ejection portion.

9. The biological fluid injection tool according to any one of claims 1 to 8, wherein,

the liquid medicine discharge portion extends and protrudes toward the distal end side than the gas discharge portion,

the discharge opening of the gas discharge portion is formed so as to be inclined with respect to a virtual plane orthogonal to the extending direction of the chemical liquid discharge portion so as to protrude toward the distal end side of the chemical liquid discharge portion as it is separated from the chemical liquid discharge portion.

10. The biological chemical injection device according to claim 9, wherein,

the ejection opening is formed on a surface orthogonal to the ejection direction of the gas.

11. The biological fluid injection tool according to any one of claims 1 to 10, wherein,

the gas discharge portion has a flow path diameter of 0.3mm or more and 0.6mm or less.