CN116585398A - 一种具有提神防晕车功能的组合物 - Google Patents
一种具有提神防晕车功能的组合物 Download PDFInfo
- Publication number
- CN116585398A CN116585398A CN202310656891.5A CN202310656891A CN116585398A CN 116585398 A CN116585398 A CN 116585398A CN 202310656891 A CN202310656891 A CN 202310656891A CN 116585398 A CN116585398 A CN 116585398A
- Authority
- CN
- China
- Prior art keywords
- essential oil
- oil
- essence
- refreshing
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 32
- 201000003152 motion sickness Diseases 0.000 title claims abstract description 24
- 239000000341 volatile oil Substances 0.000 claims abstract description 66
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 14
- 235000001405 Artemisia annua Nutrition 0.000 claims abstract description 11
- 240000000011 Artemisia annua Species 0.000 claims abstract description 11
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000020334 white tea Nutrition 0.000 claims abstract description 11
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 10
- 239000002826 coolant Substances 0.000 claims abstract description 10
- 229940041616 menthol Drugs 0.000 claims abstract description 10
- 239000002904 solvent Substances 0.000 claims abstract description 10
- 244000024873 Mentha crispa Species 0.000 claims abstract description 9
- 235000014749 Mentha crispa Nutrition 0.000 claims abstract description 9
- 241000758794 Asarum Species 0.000 claims abstract description 7
- 240000007926 Ocimum gratissimum Species 0.000 claims abstract description 7
- 235000004066 Ocimum gratissimum Nutrition 0.000 claims abstract description 7
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 10
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims description 10
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims description 10
- 229940116229 borneol Drugs 0.000 claims description 10
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 235000004347 Perilla Nutrition 0.000 claims description 8
- 239000001926 citrus aurantium l. subsp. bergamia wright et arn. oil Substances 0.000 claims description 7
- 239000000284 extract Substances 0.000 claims description 7
- 239000003921 oil Substances 0.000 claims description 7
- 235000019198 oils Nutrition 0.000 claims description 7
- DCSCXTJOXBUFGB-JGVFFNPUSA-N (R)-(+)-Verbenone Natural products CC1=CC(=O)[C@@H]2C(C)(C)[C@H]1C2 DCSCXTJOXBUFGB-JGVFFNPUSA-N 0.000 claims description 6
- DCSCXTJOXBUFGB-SFYZADRCSA-N (R)-(+)-verbenone Chemical compound CC1=CC(=O)[C@H]2C(C)(C)[C@@H]1C2 DCSCXTJOXBUFGB-SFYZADRCSA-N 0.000 claims description 6
- 240000002319 Citrus sinensis Species 0.000 claims description 6
- 235000005976 Citrus sinensis Nutrition 0.000 claims description 6
- 239000010502 orange oil Substances 0.000 claims description 6
- DCSCXTJOXBUFGB-UHFFFAOYSA-N verbenone Natural products CC1=CC(=O)C2C(C)(C)C1C2 DCSCXTJOXBUFGB-UHFFFAOYSA-N 0.000 claims description 6
- 244000014047 Polianthes tuberosa Species 0.000 claims description 5
- 235000016067 Polianthes tuberosa Nutrition 0.000 claims description 5
- ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical compound C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 claims description 5
- 235000021028 berry Nutrition 0.000 claims description 5
- 239000008164 mustard oil Substances 0.000 claims description 5
- 244000124853 Perilla frutescens Species 0.000 claims description 4
- 239000001738 pogostemon cablin oil Substances 0.000 claims description 4
- 240000000560 Citrus x paradisi Species 0.000 claims description 3
- 239000010634 clove oil Substances 0.000 claims description 3
- 239000010649 ginger oil Substances 0.000 claims description 3
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 claims 2
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 claims 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 claims 1
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 claims 1
- 239000005456 alcohol based solvent Substances 0.000 claims 1
- 229930007744 linalool Natural products 0.000 claims 1
- 239000000686 essence Substances 0.000 abstract description 41
- 230000000694 effects Effects 0.000 abstract description 28
- 238000000222 aromatherapy Methods 0.000 abstract description 13
- 238000001816 cooling Methods 0.000 abstract description 6
- 230000002045 lasting effect Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 3
- 230000008569 process Effects 0.000 abstract description 3
- 239000002304 perfume Substances 0.000 description 8
- 241000196324 Embryophyta Species 0.000 description 7
- 206010047700 Vomiting Diseases 0.000 description 7
- 230000001737 promoting effect Effects 0.000 description 7
- 230000002929 anti-fatigue Effects 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
- 206010016256 fatigue Diseases 0.000 description 6
- 244000062730 Melissa officinalis Species 0.000 description 5
- 235000010654 Melissa officinalis Nutrition 0.000 description 5
- -1 ether alcohols Chemical class 0.000 description 5
- 239000000865 liniment Substances 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 230000008673 vomiting Effects 0.000 description 5
- 101100186820 Drosophila melanogaster sicily gene Proteins 0.000 description 4
- 206010028813 Nausea Diseases 0.000 description 4
- 241000229722 Perilla <angiosperm> Species 0.000 description 4
- 125000003118 aryl group Chemical group 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 230000008693 nausea Effects 0.000 description 4
- 235000013599 spices Nutrition 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 240000005636 Dryobalanops aromatica Species 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 230000008451 emotion Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000003205 fragrance Substances 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000002147 killing effect Effects 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- 230000001953 sensory effect Effects 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 240000000572 Blumea balsamifera Species 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 230000001914 calming effect Effects 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 210000002249 digestive system Anatomy 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 230000027119 gastric acid secretion Effects 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000002889 sympathetic effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- DTGKSKDOIYIVQL-NQMVMOMDSA-N (1s,4r,6r)-1,7,7-trimethylbicyclo[2.2.1]heptan-6-ol Chemical compound C1C[C@]2(C)[C@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-NQMVMOMDSA-N 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 206010019133 Hangover Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 241000218195 Lauraceae Species 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 240000002505 Pogostemon cablin Species 0.000 description 1
- 235000011751 Pogostemon cablin Nutrition 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 244000178231 Rosmarinus officinalis Species 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 244000250129 Trigonella foenum graecum Species 0.000 description 1
- 235000001484 Trigonella foenum graecum Nutrition 0.000 description 1
- 239000002269 analeptic agent Substances 0.000 description 1
- 230000000922 anti-bactericidal effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 238000009661 fatigue test Methods 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000005176 gastrointestinal motility Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 210000005037 parasympathetic nerve Anatomy 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 1
- 235000019633 pungent taste Nutrition 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 230000001846 repelling effect Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 238000013077 scoring method Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000001256 steam distillation Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 235000001019 trigonella foenum-graecum Nutrition 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Toxicology (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
本发明公开了一种具有提神防晕车功能的组合物,包括:0.1‑45重量百分比的清凉剂,所述清凉剂包括天然樟脑、薄荷脑;0.2‑25重量百分比的精油,所述精油包括白茶精油、青蒿精油、丁香罗勒精油、留兰香精油、细辛精油;0.1‑20重量百分比的溶剂;0.2‑10重量百分比的香精。本技术方案所提供的一种具有提神防晕车功能的组合物,含有多种清凉组分,在使用过程中可以发挥清凉、提神醒脑的功能,作用持久,不仅如此,本技术方案结合芳香疗法,组分中含有多种精油及香精,所制备的组合物能够多方位综合提神、兼具防晕车效果、并增加了用户体验。
Description
技术领域
本发明涉及日用化工技术领域,特别涉及一种具有提神防晕车功能的组合物。
背景技术
随着人们生活节奏的加快,工作压力的增大,大脑长期处于高度紧张状态,经常会出现犯困、打盹的现象,严重影响工作。近年来,通过香料愉悦精神、稳定情绪的芳香疗法(香薰)逐渐普及,芳香疗法对人体大脑具有镇静、清醒、兴奋等作用,已通过测定脑电波等实验方法被证实,芳香疗法也在世界各地被广泛用于临床,现代芳香疗法多采用香水、鼻烟等形式,其中的挥发成分经由鼻粘膜吸收产生嗅觉,经过肺部气体交换进入人体循环,共同促发中枢神经镇定或兴奋,但芳香疗法的提神效果一般较为温和,提神醒脑效果欠佳。因此,现有芳香疗法进行提神的技术方案具有提神醒脑效果欠佳的技术缺陷。
发明内容
针对以上技术缺陷,本发明实施例提供了一种具有提神防晕车功能的组合物,旨在解决现有芳香疗法进行提神的技术方案具有提神醒脑效果欠佳的技术缺陷。
本发明实施例所提供的一种具有提神防晕车功能的组合物,包括:
0.1-45重量百分比的清凉剂,所述清凉剂包括天然樟脑、薄荷脑;
0.2-25重量百分比的精油,所述精油包括白茶精油、青蒿精油、丁香罗勒精油、留兰香精油、细辛精油;
0.1-20重量百分比的溶剂;
0.2-10重量百分比的香精。
其中,所述清凉剂还包括冰片。
其中,所述精油还包括芳樟油、5倍甜橙油、生姜油、佛手柑油、紫苏提取液、丁香油、广藿香油、芥末油、马鞭草酮中的一种或多种组合。
其中,所述溶剂为醇类、醚醇类溶剂中的一种。
其中,所述香精为柏林少女香精、晚香玉香精、浆果盛典香精、西西里的蓝香精、费洛蒙香精、和风蜜柚香精的一种或多种组合。
本发明实施例所提供的一种具有提神防晕车功能的组合物,包括:0.1-45重量百分比的清凉剂,所述清凉剂包括天然樟脑、薄荷脑;0.2-25重量百分比的精油,所述精油包括白茶精油、青蒿精油、丁香罗勒精油、留兰香精油、细辛精油;0.1-20重量百分比的溶剂;0.2-10重量百分比的香精。本技术方案所提供的一种具有提神防晕车功能的组合物,含有多种清凉组分,在使用过程中可以发挥清凉、提神醒脑的功能,作用持久,不仅如此,本技术方案结合芳香疗法,组分中含有多种精油及香精,多方位综合提神、兼具防晕车效果、并增加了用户体验。
具体实施方式
为使本发明实施例的目的、技术方案和优点更加清楚,下面对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例是本发明的一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动的前提下所获得的所有其他实施例,都属于本发明保护的范围。
本发明实施例中各原料介绍:
天然樟脑,购于河北冠朗生物科技有限公司,CAS号为464-49-3;
薄荷脑,购于河北贞田食品添加剂有限公司,CAS号为1490-04-6;
冰片,购于江西源上草香料有限公司,CAS号为464-45-9;
白茶精油,购于吉安市青原区文源香料有限公司;
青蒿精油,购于深圳市国鑫香精香料有限公司,货号为GX-046;
丁香罗勒精油,购于吉安博锐香料油有限公司,货号为BR-J064;
留兰香精油,购于颇黎芳香医药科技实力供应商,PES0602;
细辛精油,购于深圳市鼎诚植物香料有限公司,货号为DC-116;
芳樟油,购于深圳市鼎诚植物香料有限公司,货号为DC-066;
5倍甜橙油,购于深圳市鼎诚植物香料有限公司,货号为DC-063;
生姜油,购于江西万香萃生物科技有限公司,货号为WXC-004-1;
佛手柑油,购于颇黎芳香医药科技实力供应商,货号为PEB0601;
紫苏提取液,购于深圳市国鑫香精香料有限公司,货号为GX-060;
丁香油,购于江西亿森源植物香料有限公司,货号为DF0021;
广藿香油,购于江西亿森源植物香料有限公司,货号为gb1;
芥末油,购于江西亿森源植物香料有限公司,货号为df00013;
马鞭草酮,购于颇黎芳香医药科技实力供应商,货号为OER0401;
柏林少女香精,购于曼氏香精香料有限公司,货号为E23000755;
晚香玉香精,兰汐生物科技(山东)集团有限公司,货号为20211105023;
浆果盛典香精,购于曼氏香精香料有限公司,货号为E22015293;
西西里的蓝香精,购于曼氏香精香料有限公司,货号为W1634715;
费洛蒙香精,厦门费洛蒙香水有限公司,货号为flmxj-02;
和风蜜柚香精,购于曼氏香精香料有限公司,货号为E21116662;
乙醇,购于常州市启迪化工有限公司,CAS号为64-17-5;
风油精,购于山东星美生物科技有限公司;
应当理解,当在本说明书和所附权利要求书中使用时,术语“包括”和“包含”指示所描述特征、整体、步骤、操作、元素和/或组件的存在,但并不排除一个或多个其它特征、整体、步骤、操作、元素、组件和/或其集合的存在或添加。
还应当理解,在本发明说明书中所使用的术语仅仅是出于描述特定实施例的目的而并不意在限制本发明。如在本发明说明书和所附权利要求书中所使用的那样,除非上下文清楚地指明其它情况,否则单数形式的“一”、“一个”及“该”意在包括复数形式。
还应当进一步理解,在本发明说明书和所附权利要求书中使用的术语“和/或”是指相关联列出的项中的一个或多个的任何组合以及所有可能组合,并且包括这些组合。
本发明公开了一种具有提神防晕车功能的组合物,包括:
0.1-45重量百分比的清凉剂,所述清凉剂包括天然樟脑、薄荷脑;薄荷脑,也叫薄荷醇,是一种萜类有机化合物,有薄荷的特殊香气,味初灼热后清凉,在医药上用作刺激药,作用于皮肤或粘膜,有清凉止痒作用,可以刺激人体交感神经引起交感神经兴奋,从而抑制副交感神经兴奋,并起到提神醒脑、解除疲劳以及清凉解晕等作用,以防止晕车时出现的头晕、呕吐等症状;天然樟脑,樟科植物的枝、干、叶及根部,经提炼制得的颗粒状结晶,是萜类化合物,具有通关窍、利滞气、杀虫止痒、消肿止痛、缓解恶心的作用功效,气味相对清香,可做香料,还有一定的药效。
0.2-25重量百分比的精油,所述精油包括白茶精油、青蒿精油、丁香罗勒精油、留兰香精油、细辛精油;青蒿精油是从黄花蒿中提取得到的挥发油,现代研究已证明青蒿挥发油具有抗菌、抗癌、抗病毒、抗炎、驱蚊、杀虫、抗氧化等功效。白茶精油源自白茶中,一般采用超分子萃取法进行提取,实验研究表明,白茶精油具有抗炎、抗菌、抗病毒、抗氧化、促细胞新生、美白等功效。丁香罗勒精油为罗勒精油与丁香精油的混合物,罗勒精油又名紫苏精油,治偏头痛,助消化及呼吸系统,抗痉挛,杀菌,促进血液循环,还有提神,改善功能失调,稳定情绪,抗沮丧的作用;丁香精油有益于消化系统,可以缓解呕吐反胃。留兰香精油有助于解决消化方面的问题,例如呕吐、胀气、便秘与腹泻,似可放松胃壁肌肉,缓解打嗝与恶心的感觉,有助于减轻旅途劳累以及晕车的一些症状。
0.1-20重量百分比的溶剂,溶剂可使各组分充分溶解并发挥功效。
0.2-10重量百分比的香精,香精的引入是受到芳香疗法的启发,通过香料愉悦精神、稳定情绪的作用已人所共知,其镇静、清醒、兴奋作用也逐渐根据测定脑电图等被证实,芳香疗法(香薰)也在世界各地被广泛地应用。
其中,所述清凉剂还包括冰片。冰片,又名片脑、桔片、艾片、龙脑香、梅花冰片、羯布罗香、梅花脑、冰片脑、梅冰等,是由菊科艾纳香茎叶或樟科植物龙脑樟枝叶经水蒸汽蒸馏并重结晶而得,气清香,味辛、凉,具有挥发性。
其中,所述精油还包括芳樟油、5倍甜橙油、生姜油、佛手柑油、紫苏提取液、丁香油、广藿香油、芥末油、马鞭草酮中的一种或多种组合。5倍甜橙油对于紧张状态下的肠胃道具有安抚作用,能改善因为不安而造成的腹泻、便秘等消化系统的不适,还能刺激胆汁分泌,让食欲不振的问题获得改善,此外,宿醉的恶心、晕车反胃,也能利用柑橘类的清甜香味来舒缓。佛手柑油中含有有机酸,而且气味芳香,在食用后一般能够促进胃酸的分泌,从而对于胃酸分泌减少所引起的胃肠蠕动慢以及消化不良能够起到改善的作用。紫苏提取液由紫苏提取而来,紫苏味辛,能行气解中宽,和胃止呕,可用于治疗中焦气滞所致的胸闷、恶心、呕吐。广藿香油来源于广藿香,广藿香有解热止呕的功效,据中医方中所说,广藿香甘辛温而味苦,有除烦生津、健胃止吐、清热利水等作用,广藿香油具有清热利湿、消炎止痛之功效,对痢疾以及肺结核等病症有良好的治疗和疗效。马鞭草酮,是酮类的迷迭香,含有氧化物,氧化物属于挥发性物质,对晕车头晕,精神不振等都有帮助,也有很好的消炎杀菌能力。
其中,所述溶剂为醇类、醚醇类溶剂中的一种。
其中,所述香精为柏林少女香精、晚香玉香精、浆果盛典香精、西西里的蓝香精、费洛蒙香精、和风蜜柚香精的一种或多种组合。
表1实施例1-4中各组分的配料比
实施例1 | 实施例2 | 实施例3 | 实施例4 | |
天然樟脑 | 17.5% | 17.5% | 17.5% | 17.5% |
薄荷脑 | 17.5% | 17.5% | 17.5% | 17.5% |
冰片 | 10% | 10% | 10% | 10% |
白茶精油 | 5% | 5% | 5% | 6% |
青蒿精油 | 5% | 5% | 5% | 6% |
丁香罗勒精油 | 3% | 3% | 3% | 3% |
留兰香精油 | 3% | 3% | 3% | 3% |
细辛精油 | 3% | 3% | 3% | 3% |
芳樟油 | 2% | / | / | 1% |
5倍甜橙油 | / | 2% | / | / |
生姜油 | / | / | 2% | / |
佛手柑油 | / | / | 2% | / |
紫苏提取液 | / | 2% | / | / |
丁香油 | / | 2% | / | / |
广藿香油 | 2% | / | / | 1% |
芥末油 | 2% | / | / | 1% |
马鞭草酮 | / | / | 2% | 1% |
柏林少女香精 | / | / | / | 10% |
晚香玉香精 | / | / | 10% | / |
浆果盛典香精 | / | 5% | / | / |
西西里的蓝香精 | / | 5% | / | / |
费洛蒙香精 | 5% | / | / | / |
和风蜜柚香精 | 5% | / | / | / |
乙醇 | 20% | 20% | 20% | 20% |
按表1中各组分的配比分别将清凉剂、精油、香精溶于乙醇溶剂中,并充分混合制备实施例1-4中的组合物,通过相关实验对实施例1-4中组合物进行分析检测。
测试例1,功效评价:
为验证本技术方案所制备的组合物的提神醒脑功效,将实施例4中所制备的组合物进行人群试用比较实验。随机选取某工厂车间人员,各组观察45人,其中操作部一组工人9人、操作部二组工人9人、操作部三组工人9人、品质部一组工人9人、品质部二组工人9人,每人分别用装有风油精及实施例4中组合物的滚珠瓶在太阳穴和人中穴涂擦6圈,立即计时,共观察60分钟,空白对照组选用无色无香湿巾。
评分方法:A为清凉醒脑起效时间,10秒内起效记满分,每延迟10秒减1分,最高10分;B为提神抗疲劳持续时间,持续时间6min记1分,持续60min记满分,最高10分,权重值4;C舒适度,最高10分,权重值3;分数取45人打分的平均值,总分为A、B、C分数之和,以总分最高者为最佳,计算方法同上,结果见表2。
表2本技术方案所提供组合物与市场近似产品的使用效果比较表
序号 | A | B | C | 综合评分 |
阴性对照组(无色无香湿巾) | 0 | 1 | 5 | 6 |
阳性对照组(风油精) | 8 | 2 | 2 | 12 |
实施例4中的组合物 | 7 | 5 | 9 | 21 |
实验表明,本技术方案所提供组合物得分最高,提神抗疲劳持续时间以及舒适度较好的,起效时间稍弱。
测试例2,抗疲劳测试:
为验证本技术方案所制备的组合物的抗疲劳功效,将实施例4中所制备的组合物进行人群试用比较实验。
实验对象:选取某设计公司办公室工作人员,随机抽取三组成员,各组观察每组15人,其中,设计部一部6人,设计部二部6人,采购部3人;A1组为对照组,A2组为实验组,A3组为空白组,三组成员平均年龄相仿,在同一公司工作,具有齐同可比性。
分组后,选取下午1:30-3:00时间区间分别对A1组、A2组、A3组的成员进行测试,其中:对A1组的成员分别使用市售风油精,取其喷雾0.5ml涂抹在手心上,并分别涂抹在各成员的的人中、耳朵后背、眉心、太阳穴等处,随后进行工作等活动,记录抗疲劳的持续时间,并收集各成员的感官测试效果反馈;对A2组的成员分别使用实施例4中的组合物进行涂抹,记录抗疲劳的持续时间,并收集各成员的感官测试效果反馈;对A3组的成员分别使用纯净水进行涂抹,记录抗疲劳的持续时间,并收集各成员的感官测试效果反馈,实验结果记录如表3所示。
表3本技术方案所提供组合物与市场近似产品的抗疲劳效果比较表
实验表明,本技术方案所提供组合物气味接受程度得分最高,提神持续时间以及舒适度较好,提神生效时间与市售同类产品相差不大。
本发明实施例所提供的一种具有提神防晕车功能的组合物,包括:0.1-45重量百分比的清凉剂,所述清凉剂包括天然樟脑、薄荷脑;0.2-25重量百分比的精油,所述精油包括白茶精油、青蒿精油、丁香罗勒精油、留兰香精油、细辛精油;0.1-20重量百分比的溶剂;0.2-10重量百分比的香精。本技术方案所提供的一种具有提神防晕车功能的组合物,含有多种清凉组分,在使用过程中可以发挥清凉、提神醒脑的功能,作用持久,不仅如此,本技术方案结合芳香疗法,多方位综合提神,且增加产品的用户体验效果,是一种应用广泛、兼具提神、防晕车、抗疲劳的精油组合物。
以上所述,仅为本发明的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,可轻易想到各种等效的修改或替换,这些修改或替换都应涵盖在本发明的保护范围之内。因此,本发明的保护范围应以权利要求的保护范围为准。
Claims (5)
1.一种具有提神防晕车功能的组合物,其特征在于,包括:
0.1-45重量百分比的清凉剂,所述清凉剂包括天然樟脑、薄荷脑;
0.2-25重量百分比的精油,所述精油包括白茶精油、青蒿精油、丁香罗勒精油、留兰香精油、细辛精油;
0.1-20重量百分比的溶剂;
0.2-10重量百分比的香精。
2.根据权利要求1所述的一种具有提神防晕车功能的组合物,其特征在于,所述清凉剂还包括冰片。
3.根据权利要求1所述的一种具有提神防晕车功能的组合物,其特征在于,所述精油还包括芳樟油、5倍甜橙油、生姜油、佛手柑油、紫苏提取液、丁香油、广藿香油、芥末油、马鞭草酮中的一种或多种组合。
4.根据权利要求1所述的一种具有提神防晕车功能的组合物,其特征在于,所述溶剂为醇类、醚醇类溶剂中的一种。
5.根据权利要求1所述的一种具有提神防晕车功能的组合物,其特征在于,所述香精为柏林少女香精、晚香玉香精、浆果盛典香精、西西里的蓝香精、费洛蒙香精、和风蜜柚香精的一种或多种组合。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310656891.5A CN116585398A (zh) | 2023-06-05 | 2023-06-05 | 一种具有提神防晕车功能的组合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310656891.5A CN116585398A (zh) | 2023-06-05 | 2023-06-05 | 一种具有提神防晕车功能的组合物 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN116585398A true CN116585398A (zh) | 2023-08-15 |
Family
ID=87611651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310656891.5A Pending CN116585398A (zh) | 2023-06-05 | 2023-06-05 | 一种具有提神防晕车功能的组合物 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN116585398A (zh) |
-
2023
- 2023-06-05 CN CN202310656891.5A patent/CN116585398A/zh active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105504966B (zh) | 一种平版胶印油墨 | |
CN106318038A (zh) | 一种水性uv油墨 | |
CN110339331A (zh) | 一种植物舒缓精油 | |
CN106727032A (zh) | 一种多功能纯露及其制备方法 | |
KR100795993B1 (ko) | 아토피성 피부용 화장료 조성물 | |
CN104206450A (zh) | 一种中药与表面活性剂复配的电热蚊香液及制备方法 | |
CN111297948B (zh) | 一种治疗蠕形螨睑缘炎的眼贴和制备方法 | |
CN116585398A (zh) | 一种具有提神防晕车功能的组合物 | |
CN106336730A (zh) | 一种环保水性黑色油墨 | |
CN110724601A (zh) | 炮仗花复合香精及其在牙膏中的应用 | |
JPWO2002028404A1 (ja) | 点眼剤 | |
CN100355413C (zh) | 一种祛屑的姜洗发液 | |
CN104740444A (zh) | 具有提神功效的复方精油喷雾剂 | |
KR101715076B1 (ko) | 석창포를 주재료로 하는 기능성 샴푸 및 그 제조방법 | |
CN109432318B (zh) | 复方精油、其应用以及复方精油产品 | |
CN112891504A (zh) | 一种以生姜药渣为基材的四季护肤防疫生姜膏及制备方法 | |
JPH11343497A (ja) | 化粧料 | |
CN109939209A (zh) | 一种快速通鼻乳膏 | |
CN111388619B (zh) | 一种桢楠中药动香及其制备方法 | |
CN106318037A (zh) | 一种天然水性油彩墨水 | |
CN106118220A (zh) | 一种改良型印刷油墨 | |
CN105691257A (zh) | 一种负离子驱蚊型汽车座椅头枕及应用该头枕的汽车座椅 | |
CN116602879A (zh) | 一种除螨组合物、含有该组合物的除螨添加剂及其制备方法及应用 | |
CN104924936A (zh) | 驱蚊防菌型汽车座椅头枕及应用该头枕的汽车 | |
CN117883324A (zh) | 一种精油组合物及应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |