CN116355923A - New mutation site of congenital heart disease related DGKD gene and application thereof - Google Patents
New mutation site of congenital heart disease related DGKD gene and application thereof Download PDFInfo
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Abstract
The invention discloses a new mutation site of a congenital heart disease related DGKD gene and application thereof; the nucleotide sequence of the gene is shown as SEQ ID NO.1, the new mutation site is positioned at 35949 th site, rs542595931 is G-A and 80316 th site, and rs1345260651 is A-G. The invention relates to a method for detecting the nucleotide variation, which comprises the following steps: step one, collecting three family samples, and typing potential new mutation sites of the sequences; step two, the genetic variation at positions 35949 and 80316 was analyzed using Sanger sequencing. The invention lays a foundation for researching the relation between the new variation of the DGKD gene and the congenital heart disease, provides a molecular target for predicting the risk of suffering from the congenital heart disease, and simultaneously provides a theoretical basis for early screening of the congenital heart disease based on the gene.
Description
Technical Field
The invention belongs to the technical field of molecular diagnosis and gene detection, relates to new variation of congenital heart disease candidate genes and correlation of the new variation with congenital heart disease candidate genes, in particular to an identification and application method of the new variation of DGKD genes in the technical field of gene detection, and particularly relates to new variation sites of the related DGKD genes of the congenital heart disease and application of the new variation sites.
Background
Congenital heart disease (Congenital heart disease, CHD) is a major class of developmental deformities of the heart involving structural and functional defects of the heart, with an incidence of 0.5-1% in live infants. CHD is the most common birth defect in humans, severely jeopardizing infant health, where the bluish violet congenital heart disease is the leading cause of complex deformity and high mortality in infants. More than 10 tens of thousands of congenital heart disease infants born in China are born annually, of which about 80% are simple CHD without syndrome. Although modern genetics and imaging have made great progress in the study of the genetic and molecular mechanisms of CHD, a significant proportion of CHD patients are still unknown in their pathogenesis and are treated primarily by surgical means. Even if CHD patients survive through surgical correction, severe problems such as pulmonary arterial hypertension, heart failure complications and the like still occur in the future, and huge pains and economic burdens are brought to the patients and families thereof. The elucidation of CHD pathogenesis is the basis for improving early intervention, prevention and control and treatment of CHD, and has great scientific value and social significance for improving the health and birth population quality of children in China. Through large-scale complete genome sequencing of the CHD family and combination of clinical gene detection technology, the method is beneficial to perfecting the genomics and clinical data of the CHD in China and further elucidating the pathogenesis of the CHD, provides theoretical basis for molecular diagnosis thereof, and also provides a new idea for researching the etiology of similar diseases.
Factors known to cause CHD are mainly environmental and genetic factors. The environmental factors mainly comprise medicines taken in gestation period, virus infection, environmental pollution, radiation, etc. Compared with complex environmental factors, the genetic factors are easy to quantitatively analyze. Since the first demonstration of CHD induction by heterozygous mutations in the NKX2-5 gene, genetic factors have been increasingly gaining importance in CHD development. To date, tens of genes associated with simple CHD have been found in humans, including transcription and regulatory factor genes during cardiac formation (e.g., NKX2-5, tbx1 and GATA 4), developmental signaling pathway molecular genes (e.g., NOTCH2 and JAG 1), cardiac structural genes (e.g., ELN and MYH 6), and the like. Both loss of function (LOF) mutations and gain of function (GOF) mutations of related genes can lead to CHD. However, currently known single-gene variation can only explain 3-5% of simple CHD, and the discovery and identification of new CHD related genes are scientific problems to be solved urgently.
CHD is complex in etiology and has a variety of clinical phenotypes. For example: fallotetraia (Tetralogy of Fallot, TOF), pulmonary arterial occlusion/ventricular septal defect (Pulmonary atresia/ventricular septal defect, PA/VSD), perpetuating arterial trunk (Permanent truncus arteriosus, PTA), aortic arch dissection (interrupted aortic arch, IAA), aortic transposition (Transposition of the great arteries, TGA), right ventricular double outlet (Double outlet right ventricle, DORV), and the like. Elucidating the genetic characteristics and pathogenesis of different types of CHD will greatly promote the research of CHD etiology and provide theoretical support for molecular diagnosis and early intervention thereof. Because of the complex mechanism of onset of the congenital heart disease, it is particularly important to select a suitable sample in the family and to take a suitable strategy for research. The collection of the congenital heart disease families not only provides a favorable guarantee for exploring the occurrence mechanism of the congenital heart disease, but also can discover new disease phenotypes, reveal new functions of pathogenic genes and provide a direction for research of the pathogenic genes.
In recent years, the development of high-throughput sequencing technology brings new opportunities for research on genetic etiology of complex diseases such as CHD. Analysis of the full exome data of the largest scale CHD cohort (2871 pre-evidence, of which 2645 core families) to date showed that new variations of about 440 genes are associated with CHD, with new autosomal dominant genetic variations and autosomal recessive genetic variations accounting for 8% and 2%, respectively; page et al found that pathogenic variation significantly aggregated in NOTCH1 and FLT4 in 829 Fabry-Perot quadruple (TOF) patients by whole-exome sequencing technique, and that variation of these 2 genes could explain 6.9% of TOF cases enrolled by the study; liu et al, through sequencing studies of the complete exome of the aortic translocated infant and core family (trio), found that pathogenic mutations are enriched in cilia-related genes, and that some cases show either oligogenic or polygenic genetic patterns. However, current research into genetic causative factors of CHD has been focused mainly on the protein-encoding gene, and there are a large number of non-coding regions, which are closely related to the embryonic heart development process and are also key factors for CHD. The clinical samples can be analyzed by whole genome sequencing, so that common variation and rare variation can be detected, and variation information of a protein coding region and a non-coding region can be obtained simultaneously, thereby being a necessary path for comprehensively revealing the genetic etiology of CHD.
The DGKD gene encodes a cytoplasmic enzyme, diglyceride kinase, which phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerols and phosphatidic acids are two lipids that act as second messengers in signal tandem. Their cell concentration is regulated by the encoded protein and is therefore believed to play an important role in cell signaling. Furthermore, DGKD regulates, for example, PKC and EGF receptor signaling pathways by controlling the level of diacylglycerol and plays a key role in the development process. DGKD has been reported to play a possible role in the etiology of seizures. Although there have been many reports of the correlation of various types of variation on genes with congenital heart disease, there are no reports of the correlation of DGKD genes with congenital heart disease, and there are no reports of the correlation of new variation with congenital heart disease. Therefore, the invention provides the application value of the DGKD gene in screening congenital heart diseases for the first time, which not only has great significance for early intervention of congenital heart diseases, but also provides an important clue for exploring pathogenesis of congenital heart diseases.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide a novel mutation site of a congenital heart disease related DGKD gene and application thereof. The invention lays a foundation for researching the relation between the new variation of the DGKD gene and the congenital heart disease, provides a theoretical basis for early intervention of the congenital heart disease, and also provides an important clue for exploring the pathogenesis of the congenital heart disease.
The aim of the invention is achieved by the following technical scheme,
in a first aspect, the invention provides an isolated nucleotide containing a new mutation site, the sequence of the nucleotide is shown as SEQ ID NO.1, the new mutation site is located at 35949 th position rs542595931 as G-A and 80316 rd position rs1345260651 as A-G.
In a second aspect, the invention provides an isolated nucleotide having a sequence as set forth in SEQ ID NO:1, and 35949 is G while 80316 is A.
In a third aspect, the invention provides the use of the isolated nucleotide containing a new mutation site as a molecular marker of congenital heart disease, or in the preparation of a reagent or kit for assisting in screening or detecting congenital heart disease.
As one embodiment of the invention, the reagent comprises a primer, a probe, a chip, or an antibody.
As an embodiment of the invention, the kit contains one or more reagents selected from the group consisting of:
(a) Specific primers for detecting one or both of said novel mutation sites;
(b) A specific probe for detecting one or both of said novel mutation sites;
(c) A chip for detecting one or two of the new variation sites;
(d) And the specific antibody is used for detecting the mutation of one or two amino acids corresponding to the new mutation sites.
As one embodiment of the present invention, the new mutation site is located at 35949 th position, rs542595931 is g→a, and the primer is:
forward primer 5'-TCTGACAGATGCCAGCGTAG-3' SEQ ID No.2,
reverse primer 5'-ACTGTTGTTGACGTTTTTGGT-3' SEQ ID No.3;
the new mutation site is positioned at 80316 th site, rs1345260651 is A-G, and the primer is:
forward primer 5'-CATGGACCACTTCTCAGGGA-3' SEQ ID No.4,
the reverse primer 5'-CTCACGGCACACATTGCAGTA-3' SEQ ID No.5.
In a fourth aspect, the invention provides a kit for aiding in the screening or detection of congenital heart disease, said kit comprising: according to the sequence set forth in SEQ ID NO:1, and primer pairs designed at new mutation sites rs542595931 and rs1345260651 of the sequence shown in the formula 1.
As one embodiment of the present invention, the new mutation site is located at position 35949, rs542595931 is g→a, and the primer pair is:
forward primer 5'-TCTGACAGATGCCAGCGTAG-3' SEQ ID No.2,
reverse primer 5'-ACTGTTGTTGACGTTTTTGGT-3' SEQ ID No.3;
the new mutation site is positioned at 80316 th site, rs1345260651 is A-G, and the primer pair is:
forward primer 5'-CATGGACCACTTCTCAGGGA-3' SEQ ID No.4,
the reverse primer 5'-CTCACGGCACACATTGCAGTA-3' SEQ ID No.5.
In a fifth aspect, the present invention provides a method for using the kit for non-diagnostic purposes, comprising the steps of:
s1, extracting DNA of three family samples;
s2, amplifying by using the primer pair to obtain an amplified product;
s3, detecting whether new mutation sites rs542595931 and rs1345260651 shown in SEQ ID NO.1 exist in the family child sample by adopting a Sanger sequencing method.
As an embodiment of the present invention, step S3 includes the steps of: the sites rs542595931 and rs1345260651 of the samples taken are typed by using an ABI 3730XL PCR instrument, and whether genetic variation exists at 35949 th and 80316 th positions is detected.
As one embodiment of the present invention, in step S2, the length of the amplification product is 50-150bp.
As one embodiment of the present invention, in step S2, the length of the primer is 15-25bp.
As one embodiment of the present invention, in step S2, the total volume of the amplified amplification reaction system is 50. Mu.l, wherein,
as an embodiment of the present invention, in step S2, the amplification reaction conditions: 94 ℃ for 2mins;40× (94 ℃ 30s;58 ℃ 30s,72 ℃ 30 s); and at 72℃for 10mins.
In a sixth aspect, the invention provides a primer pair for detecting SNP loci of the nucleotides, wherein the sequence of the nucleotides is shown as SEQ ID NO. 1;
the new mutation site is positioned at 35949 th site, rs542595931 is G-A, and the primer pair is:
forward primer 5'-TCTGACAGATGCCAGCGTAG-3' SEQ ID No.2,
reverse primer 5'-ACTGTTGTTGACGTTTTTGGT-3' SEQ ID No.3;
the new mutation site is positioned at 80316 th site, rs1345260651 is A-G, and the primer pair is:
forward primer 5'-CATGGACCACTTCTCAGGGA-3' SEQ ID No.4,
the reverse primer 5'-CTCACGGCACACATTGCAGTA-3' SEQ ID No.5.
In a seventh aspect, the invention also provides an isolated DGKD amino acid sequence having one or more mutations selected from the group consisting of: amino acid Val (V) at position 59→Ile (I), amino acid Asn (N) at position 121→Thr (T).
Compared with the prior art, the invention has the following beneficial effects: the invention lays a foundation for researching the relation between the new variation of the DGKD gene and the congenital heart disease, provides a molecular target for predicting the risk of suffering from the congenital heart disease, and simultaneously provides a theoretical basis for early screening of the congenital heart disease based on the gene.
Detailed Description
The invention will be further illustrated with reference to specific examples. It is to be understood that these examples are illustrative of the present invention and are not intended to limit the scope of the present invention. The experimental procedure, which does not address specific conditions in the following examples, is generally followed by conventional conditions, such as molecular cloning by Sambrook et al: conditions described in the laboratory Manual (New York: cold Spring HarborLaboratory Press, 1989) or as recommended by the manufacturer.
Example 1
The invention relates to a screening and obtaining method of novel mutation at 35949 th and 80316 th positions of DGKD genes, and also relates to a detection method and related separated nucleotide and primer. The invention unexpectedly discovers that SNP rs542595931 and rs1345260651 on the exon region of the DGKD gene can be used as molecular markers of congenital heart disease through family analysis of whole genome sequencing, and the specific information of the gene is the DGKD gene LOCUS NG_029495, and the total length is 117605bp.
Specifically, the experiment used Illumina TruSeq Nano DNA library prep kit to construct a whole genome sequencing library and sequenced on the Illumina NovaSeq platform. The high quality sequencing data was analyzed by quality assessment and processing of the off-the-shelf data followed by the read recommended bwa+gatk analysis procedure. The method comprises the following specific steps:
a) Family genetic analysis: and analyzing different family genetic modes through sequencing variation data, and rescreening genes carrying new single nucleotide variation of a plurality of coding regions in a plurality of families, namely finding DGKD candidate genes.
B) DGKD gene mutation frequency and deleterious analysis: the frequency and harmfulness of the observed novel mutation in the DGKD gene were analyzed by evaluation of the GnomAD database and CADD software (Table 1, CADD >20 is usually highly harmful).
C) Comparison analysis of new mutation data: the novel mutation profile of the DGKD Gene was compared by comparing the novel mutation information provided by the Gene4denovo database (Table 2).
The invention adopts Sanger sequencing technology to detect the new SNP locus variation of the exon region of the DGKD gene, and discovers the missense mutation of G-A at 35949 th position of the DGKD gene, namely 59 th amino acid Val (V) -Ile (I) in the encoded protein sequence (NP-003639.2); and a 80316 A.fwdarw.G missense mutation, i.e., the 121 st amino acid Asn (N). Fwdarw.Thr (T) in the encoded protein sequence (NP-003639.2). The DGKD gene is located in the chromosome: homo sapiens Chromosome, GRCH38.p13 (233354494.. 233472098), SNP rs542595931 at chromosomal location chromoname 2:233390442,SNP rs1345260651 at chromosomal location chromoname 2:23344809. The specific nucleotide fragment sequence of the DGKD gene is shown as SEQ ID NO.1, wherein the new mutation sites are positioned at 35949 th and 80316 th positions of the sequence.
The invention designs a related primer pair aiming at the SNP rs542595931 and the SNP rs1345260651.
Specifically, primers are designed at the upstream and downstream of SNP rs542595931 and SNP rs1345260651 in the exon region of the DGKD gene, and the length of an amplified product is 50-150bp. And then typing the DGKD gene SNP loci rs542595931 and rs1345260651 of the obtained family sample by using an ABI 3730XL PCR instrument. It was found by analysis that SNP rs542595931 resulted in amino acid Val (V) to Ile (I) at position 59 in the protein sequence (NP-003639.2), whereas SNP rs1345260651 resulted in amino acid Asn (N) to Thr (T) at position 121 in the protein sequence (NP-003639.2). Since this is a substitution of amino acids of different nature, it results in a severe change in the activity of the protein encoded by the DGKD gene.
The invention has a great number of analysis techniques for detecting whether new variations exist at the sites in the DGKD gene's exon. These techniques include (but are not limited to): DNA sequencing and hybridization sequencing; enzymatic mismatch cleavage, heteroduplex analysis, dot hybridization, oligonucleotide arrays (DNA chips), mini-sequencing, molecular beacons, and the like, denaturing High Performance Liquid Chromatography (DHPLC). In another aspect, the detection methods of the invention are used to assess the relationship of the neonatal DGKD gene exon SNPs 542595931 and SNPs rs1345260651 to the development of congenital heart disease. The test sample used in the present invention is not particularly limited, and for detecting SNP, DNA or mRNA extracted from a sample such as blood, tissue or the like may be used. For the activity of the gene exon region of DGKD, any sample containing the gene exon region of DGKD, such as blood, etc., can be used.
By "isolated or purified" is meant that at the genomic DNA level, the gene sequence of each new mutation site is amplified using a primer pair and the amplified product is purified using a purification kit.
The following is a specific implementation procedure of the scheme of the invention:
samples used in this example were taken from 290 congenital heart disease patients (age 0-6 years, table 3) and from a parent blood sample from the Shanghai pediatric medical center, all participants were signed by family members in a formal informed consent form. The DGKD genomic sequences to which this example relates are obtained from GenBank and are listed in SEQ ID NO:1.
primer design: primers were designed using Primer-BLAST software and the sequence of the DGKD gene (ID: 8527) of the GenBank database as a template, and synthesized by Invitrogen corporation.
Primer information:
DNA sequence primer information of SNP rs542595931 locus of DGKD gene is amplified:
forward primer 5'-TCTGACAGATGCCAGCGTAG-3' (SEQ ID NO: 2)
Reverse primer 5'-ACTGTTGTTGACGTTTTTGGT-3' (SEQ ID NO: 3).
DNA sequence primer information of SNP rs1345260651 locus of DGKD gene is amplified:
forward primer 5'-CATGGACCACTTCTCAGGGA-3' (SEQ ID NO: 4)
Reverse primer 5'-CTCACGGCACACATTGCAGTA-3' (SEQ ID NO: 5).
PCR amplification conditions: (reagents for the system are supplied by ABI, also available from published sources), the total volume of the reaction system is 50. Mu.l, where:
PCR reaction conditions: 94 ℃ for 2mins;40× (94 ℃ 30s;58 ℃ 30s,72 ℃ 30 s); and at 72℃for 10mins.
The PCR reaction is carried out in a 96-well plate, and is placed in an ABI 3730XL PCR instrument, the mutation conditions of SNP loci rs542595931 and rs1345260651 of DGKD genes in each sample are read, and experimental results show that new mutation occurs in two families, as shown in Table 4.
It was found by analysis that SNP rs542595931 resulted in amino acid Val (V) to Ile (I) at position 59 in the protein sequence (NP-003639.2), whereas SNP rs1345260651 resulted in amino acid Asn (N) to Thr (T) at position 121 in the protein sequence (NP-003639.2). Since this is a substitution of amino acids of different nature, it results in a severe change in the activity of the protein encoded by the DGKD gene.
TABLE 1
| SNP | Base frequency number | Total number of bases | Homozygote | Base frequency | CADD |
| rs542595931 | 7 | 152176 | 0 | 0.000046 | 24.1 |
| rs1345260651 | 1 | 152194 | 0 | 0.00000657 | 22.8 |
TABLE 2
TABLE 3 Table 3
| Major diagnostics | Number of examples |
| Aortic stenosis, occlusion | 3 |
| Common arterial trunk | 5 |
| Atrial/ventricular septal defect | 12 |
| Pulmonary valve occlusion | 18 |
| Right ventricle dual outlet | 22 |
| Complete aortic translocation | 26 |
| Fallotetrad disease | 195 |
| Others | 9 |
TABLE 4 Table 4
In conclusion, the invention lays a foundation for researching the relationship between the new variation of the DGKD gene and the congenital heart disease, provides a molecular target for predicting the risk of suffering from the congenital heart disease, and simultaneously provides a theoretical basis for early screening of the congenital heart disease based on the gene.
The foregoing describes specific embodiments of the present invention. It is to be understood that the invention is not limited to the particular embodiments described above, and that various changes and modifications may be made by one skilled in the art within the scope of the claims without affecting the spirit of the invention.
Sequence listing
<110> Shanghai university of transportation
<120> mutation site of congenital heart disease related DGKD gene and application thereof
<130> DD17826
<141> 2021-12-24
<160> 5
<170> SIPOSequenceListing 1.0
<210> 1
<211> 117605
<212> DNA
<213> Homo sapiens
<400> 1
gcggtgcgcg cgctggcccg gcagcatggc ggcggcggcg ggcgcccctc cgccgggtcc 60
cccgcaaccg cctccgccgc cgccgcccga ggagtcgtcc gacagcgagc ccgaggcgga 120
gcccggctcc ccacagaagc tcatccgcaa ggtgtccacg tcgggtcaga tccgacagaa 180
ggtgagcccg cggcgcggcg gcccgggcgc gcgcccctca cgccgcggca gccccggccg 240
aggcccgtgg ccctgcccga gcggccgccc aggcccggct cggcccggcc cggggtcccg 300
cgggcgtcac cgcccctgtc gagcgtgccc cgccgctgta acgggccggc gccccgggcg 360
gagcgcgcgg cccccgacgg acggcgggcg gctgtggggc cgggcggggg gcgcgcaggt 420
gggcgccccg ggcgccgcgc gctgggcggg gggcgcgcgc cgagttgggc cgcgaggacc 480
cggaggaaac tgaggcctag atgcagggga ctgcgctcgt gccaccgagc gggtcccacg 540
cgggggctcc cggctgcgcc ccgcgggcgt ccgcggtccc caaaccccgg ttctgcacgt 600
ttctcaggag cggtcgggtg gtgtcccgcg agtgccctgc agacttccct gtggtgccct 660
cagaagtccg ctcggacccg ggtgcgaggg atcacccctt caccccttca tcccaaaagg 720
gaaggaaggg atgcgcgttc agtgaccgtc tctctcagca aagccgggac cgcgcacccg 780
cttggcaccc aactctccac ggagaactcc tgacgctaaa tgttagataa agacgcacgt 840
cctttttgca ggaggaaagt tgcaccgttt gttttcccat tgtgcttcct attgaaaaca 900
gcttacggtt tttgctccag gtgagcccgc ccggttagaa cactgcttcc tcaggcaggt 960
ggctggacag gtggctgcga gcaggctggg tccctggggc agctctggca gatccggttg 1020
gcacggactt tctcctcctg ctgcagtgcg cttttcctcc ggggcggatt aggttcagcc 1080
gttcccttca ccgtgggagc cttctcttct gtcagccttt gatacctgcg atgggggaac 1140
ctgaggtcct aacatgttac aaacaggttt gttgtgaagt gctccagtta ttcagcaaat 1200
aggtaccgaa cacctgcttt gttccgggta taacagtagc agtagtgatg ataatgatag 1260
caatagcaaa taacaattct ttaataagcc ttctatgtgc caggcacttt cttgggttag 1320
ctttacagca cttgacatgg ttagtttatt agtactggtg agaacccaat aagttggatg 1380
ctatcatctc cgtcttttgg aattggaata gaaatagaat caaggttaaa tgacttgccc 1440
agggtgtcac aggtcgtaaa tgtggatgtg tgttggaacc atggtcagga ccgtaagatg 1500
gaaggcagtt tctacaccta gggattctca gtctagttgg gagatggacg cctgtgcacc 1560
tgacatgaca acattgtaag tgccgcggaa actcggggca gagacctgcc ctggggaggc 1620
aggagtggtt tcctttaagg tgagatcttg agggataaag aattcaccag gctaagtggg 1680
taagaaatgg ccttctacat atttgaacct tgcgtctaga gctttaggca caactgcgaa 1740
atgatcagaa gttgggccag aggtggatca cgttgattag acttattagt tggaagggtt 1800
ggttagggct gaatttcgaa ggggtggtcc tttgaggggt ttgctttttg gccttgggca 1860
agaggtggcc acagaggatt gttcaaagta tgggggtgat ggatcagatg tgcttttggg 1920
aagatctcca catagcccta aatgatactg ataggagttg ctttctcctg ttgcccaggc 1980
aaggtactga ccagtgtggg gtagatcatg tgatttacaa ggttgattaa gatcaagatt 2040
gtgttgagag agatttgatt cctgggagat tccagtgttt agaattttgt tggttaggag 2100
gtgtttttgc tttccttctt ttttctccta aaacaatagc tgctatacca gctgttctgg 2160
ttgaggagga gtgatgggta gactgttaaa aatacacccc gaggacttag agtttctgaa 2220
tacagtcaca tctgctgtac agatagctta aggctgattt ttcttctgag ttgttaagag 2280
attgtcagaa tgtgggaatg cgaggttgac tgtatgtaat agctccattt tttttttttc 2340
cagcagataa gccattcaca aaattcctct ggtatctatg gtacataata gaaacatcaa 2400
aaatggtatg gggtagcagt ctgagtctaa aaagaaaaac agaactcacc ttaagtattt 2460
ggaacagaag gaatgtaatc taggggagtg gtcacacagg tgatgtgaga actgagaatg 2520
caggctgcaa tgaggcaagc cggagatgag gcaacaagca ggaaactgct gccaccccta 2580
agttggaggg tgaaggaagg agatggcatt tcagactcca gggacagctg tcacccacca 2640
aaaactgggg tcacaagggg tccatctggc agtggctgga gccttgcaag ggcacagctg 2700
ctgctgcgga tgtactgttc ccctcctgcc tgggaaccct ggccttgctg gggtcacctc 2760
ctccacaact tggactggag cagaaggaca aagaatggat ctgaggacaa gctggcccag 2820
gaccagaact gtatgtatgt caggctttta aaatattagt ctagtgcaag tcagagctgt 2880
cttaatgaag agaaaaacaa aagagaatgt cttagggcag tgctcctcaa attttaatgt 2940
gcagacacat ctcctaggga tcctgttaaa atgatgatta tggttgagta ggtctagggt 3000
gggtggggcc ttagaatgtg catttctttt tctttctttc tttctttttt tttttttttt 3060
ttgagacaag gtctcacttt gtcacccagg ctggagtgca gtggtgcgat ctcagctacg 3120
gcaacctttg cctcctgggc ttaagtgatt ttcctgcctc agcctcccaa gtagctggga 3180
ctacaggcaa atgccaccat gctggctaat ttttgtattt tgttgtagag atggagtttc 3240
cccatgttcc ccaggctggt ctcaaactcc tgagctcaag taatacaccc acctcagcct 3300
cccaaagtgc tgggattata agcttgagcc aatgcacctg gcagaatatg catttctaac 3360
aagctcccag aagatgctga tgctgctggt ccatggacca gactttgaaa aacaagacct 3420
tatggcacac atgtaaagag aagcctctcc aaacttcaaa taattcttca ggttatagat 3480
ctttagcata ttgaaaattt gatgtgtgca gatttgtgat ggccatttat cagtttagca 3540
tttcatgcat gtctgatttt ttaatatgtt cgagctcttt agagttgaag ctgtccacag 3600
caaagacatt acttcatttg tatttcctga ctacagtaca cagtaatgac tctgtagaac 3660
tgcatagcta gaatggaaag aaagaaaatg gagctaacac tccgaccagc acattcacca 3720
gcacattata aggtattttg aaatttcagt gaagaaccgt gtaattctgc aaagctatca 3780
gttaaaagag tttaatttat ttaaaagttt ctagaaagtt aacatttttt ggatatgagc 3840
atgaaagtgc ttggattcct gattttaaat ttaaacaaag cattttttcc attgtgaaat 3900
gaagactagt aaaaattagg taaagggttt aagttgtaaa aaacttaaaa aaatgcaccg 3960
cagttttatg agatataatt cacatgggat acagttcagt ggttgttagt atattcgctg 4020
ttttgcaacc atcaccacag tcaattttag aacattttca tcaccccgtt tcctctcaac 4080
tccctcaacc ataggcaaca agaatctact ttctgtctct gtgtttgctg attctggtca 4140
ttttacataa atggaatcat acaatatgtg gtctggcttc tttaacttag cataatattt 4200
ttaaggttca tccatgtcat ggcatgtatc ggtacttcat ttctttctgt tgctgggtaa 4260
tattccattc tacaggcaca ctgtatttta tttatccatt tatcagttga tggacatttg 4320
ggttatttct actttttggc tattctggat aatgctgctg tgaacattca tgcacatgtt 4380
tttgtgtgga cataggtttt catttatctt ggctatacac ctaggagtgg aagtgctggg 4440
ccatatggta atactaccgg actattttcc agctaaaaag ctgccgtaac attttacatt 4500
cccaccagct gtgtatgagg agggttccaa tttttccaca tccttgtcag taactgttat 4560
tatctctctt ttgatactag ccatcctagt agggatgaag taatgtaaaa ggtttttaat 4620
gccattttat tgtcggattt caaagtctaa actttggtgt cagatgaagt cacttcagac 4680
cctgcgcttc tagttatgaa gcatgcgatt gtggacaggg tgtctaaacc tcccttaaga 4740
cgtggtttcc tcatctgtaa acatggaaaa tattagttct tgggttggtt gtagtgaaag 4800
taaatgttaa ctctgtgttc ctgagtctca gtttccatgt ctgtaaaata gaaataacag 4860
ttgttatatc cataaaatag gaatggggat gttaactcat agaattaaat gggataattt 4920
gtgtagaaca cctaacatag tggctgatgt atagtaaatg atcactaaat ggttgctttt 4980
ggttattttt tgtctttctg attttttttt ttttttatcc cagataggaa tcatttccct 5040
gattccattt ttctccagct caggctggtc tgagtctcca tctctcggct ccagaagagc 5100
aaatacaaac aaatctggct gaaaattaac aaagaccatt ttttaaagaa atcgttaatt 5160
tattgagtac tagtgggaat accatgggct aggtattaca ttttgtattt cactggttca 5220
gtttaacagc aaatatttga gatcttaaca ttgttaactg ttgtgcgagg caccaggggt 5280
atcttattga gtaacaacaa aaatttttag agatgatagt ctagaagaca ttaataaaac 5340
aatcacacag ttaatatgaa gttgtgatgg ggacgggtgc tgatgaggag agggccagaa 5400
tactttgaga ggacatcata ggtgaatttg acctgatatc agggaggtct aggagggctt 5460
cttgaggcag tgactggctg ggtctggaag gtgagtaggg agcagtgcct tctgcttctg 5520
gcagtggtga gctgagtgac tgcagcgcca ctcttccaag cacagtctgc taataagatg 5580
atgctgaatt tctggactag gatctggggt ggctgaagat ctgtggaagt gagtgtggta 5640
tttggggctg cttttgacct tggaatctgt agtggcgtct gtagtggatt tggcatctct 5700
accaaatttg gtccacctag aacttcagga tgcccacata ataagatatt agttaaatat 5760
ctttaaaaaa attttttttc tttttttctg agacagggtc ttgctcggtc gtccaggctg 5820
gagtgcagtg gcatactgca gtctctggct gggctcaggc aatcctcctg cctcagccac 5880
ctgagtagct gggactccag atgcattcca tgatgcctgg ctaatttaaa aacacatttt 5940
tatggagacg agggtctcac tatgttgccc atgcttgggg tctcaaactc ctgggctcaa 6000
gcgatcctcc ccctttggct tcccaaagtg ctagaattac agacatgagc tactgtgcct 6060
ggccaaaatt ttttattttg agatagggtc ttgctatatt ccccaggctg gtctcaaact 6120
cctgggctca agtgatcctc ctgcttcagg cttctgagta gctgggagcg taggctcaag 6180
ccactgtgcc tggctaatta aagattttga gagtaaatca tcgtgaactt aggagaaact 6240
ctaaatccag tgttggtttc tttataagag gaaggggagg gagatttgga cagaaagaca 6300
tgttgggaaa aaggttatgg gaaaatagag ccggagatta gagttcgttg atgcaaacca 6360
aggaatgcct ggggccacca gaagctggaa gagataacag atggaatctc ccctagagcc 6420
tttagaggga gtgcggcctt ctgatccctt gatctccgac ttccagcccc cagagcagtg 6480
agacagtcaa gttttttttt tttttttttt tttccaagtt ttgttttaag ccttgaagtt 6540
ttatggcagc cctagggcag ccctggggaa agaacactgg gccctgaaca aaacatggga 6600
gccaagaggc tgagccctgt gagactgtct gagtgcctta gcagggctga ggtgccaggt 6660
tctgccaaag ggcaacagtc ctgggtgaca ccctcccctc acaatttgga ttgggatcca 6720
aagaagccac ttccaaggaa tgcgcaggag ccagaagtat tggaaggact gcagccctgc 6780
ttcaaatcac ctcagtcctc tgaaattaaa gtaatcccag tgtactagtg tctctagatt 6840
cccaacagaa gcaaacttta atcctctcta gagggagata tctccctcta atcctcccag 6900
ttatcaatgg aggcctctaa tgactttcac gagtctgttt gtacgttcat gattgtgcat 6960
acagtaaaaa aatagacatc aagggaggcg aggcacttga gctaaaacca gtcgaaacta 7020
caggctgtag acagacccac agggcttcca gactccagac ccagacttta taacaactgt 7080
gctcgttgtg ttggaggaga cacgagatca gatggagagt tttggcagag aactagaaac 7140
tatggaaaag aaccagatga aaattctagt ccacactggc cagatggctc acgcctataa 7200
tctcagcact tttggactga ggcaggtgga tcattggagg tcacgagttt gagaccagcc 7260
tggccaacat ggcaagatcc cgcctctact aaagatacta gacatttttt ttttctttta 7320
agacggagtc tcactcttgt cacccaggct gtagtgcagt ggcatgatct cagctcacta 7380
caacctttgc ctcctgggtt caagcaattc tcctgcctca gccccccgag tagctaggat 7440
tacaggtgcc catcaccacg cccagctaat tttttggtat ttttaataga gacggagtct 7500
taccatgtta gctaagctgg tctcgaactc ccaatctcag gtgatctgcc cgcctcggcc 7560
tcccaaagtg ctgggattac atgcgtgagc cacctcaccc agccaataaa agaaaattat 7620
aaaattgaaa aagcatagtg atcaaaatta actaaccaaa aaaagagcag attagaccca 7680
ggctgaaaaa attgtgtgaa ccagaagata gctcagaaga aaatacccac aaggaagcct 7740
ggagacataa aaaatggaaa aatttggaga gggtgggaga cagatatagt aagaaggtct 7800
tacttgtgtt taattgtcac aagagaggag aagtgagaga aaattgagga gacacaatat 7860
ttgaaaagat aatgtggcca ggtgcagtga ctcacgactg taatcccagc agttttggat 7920
gctgaggtgg gcggatcacc tgaggttagg agttcaagac cagcttggcc aacatggtga 7980
aaccctgtgt ctactaaaag tacaaaaatt agctgggtgt ggtggcagat gcctgtaatc 8040
ccagctactc gggaggctga ggcaggagca tcgcttgaac ctgggaagtg gaagttgcag 8100
tgagctgaga ccacaccatt acactacagc ctgggcgaca agagcgaaac tctgtattaa 8160
atagaaaaaa aagaaagaaa agtaatacct gagaattttc tacaacaaat aacaggtacc 8220
atgaacagat tcgatagccg tatgaactga aagaaccata tctaatcaat tcctggtaca 8280
cccttgtgct ctgcataatg atgtttccgg atgatgatcc acatggacaa aggtggtccc 8340
ataagattat aatgaagctg aaaaattcca attgtctagt gacgtggtag ctgttataat 8400
gttgtagggc aatgaattac ctatgtgttt gtggtgatgc tggtgtaaac agacctactg 8460
cactgcaagt ggtagaaaag tatagcacat acaagtatat acagtacata atagttgatg 8520
atgataataa acaactatgt tactggttta tgtatttact atctatactt tttattattt 8580
tagagtatat tcttcctact tatagaaaaa agaaaaacaa attgtaaaac agcctcaagc 8640
aggtccttca ggaggtatcc agaagaaggc attgttatca taggaggtga cagctccatg 8700
cacgtcattg tccctgaaga ccttccagtg ggataggatg tggaggcgga agataatgat 8760
actgatgatc ctgactctgt gtaggtctag gctaatgtgt gtgtttgttt cttagttttt 8820
aacaaaaata tttaagaagt aaaataatta aaaaaattaa aaatagaaaa aaggttatag 8880
aataaggata taaagaaaat acttttgtac aagtgtacag tgtgtgtttc aagctaaatg 8940
ttactacaaa agagtaaaaa attaaattaa aagtttataa agtaaaaata ttacagtaag 9000
ctaaggttaa tttgttattg aagaaagaaa gtctttcaaa aaataaatgt agtatagcct 9060
aagtgtacag tgtttacaaa gcatagagta ctggtcagta gtgtcctagg ccatcacatt 9120
cactcaccag tcattcactc actcatccag agcaacttcc agccctgcaa gctccagtta 9180
cggtaagtac cctatacagg tgtaccattt taaaaatctt ttatgacata tttttactgt 9240
actgtttcta tgtttagtta tatttagata cgcaaatact tgccgttgag ttatagttgc 9300
ctacagtgtc agcacagtga tgtgctctat gggtttgtag tccaagagca ataggtcatg 9360
ccatacagat gaggtgtgtg ccatctagat ttgtgaaagt acactctgtg atgttcacat 9420
aggatgaaat cacctcataa cacatttctc agaatatatg ctcattgtta agcaactgat 9480
aactgtagca ccgttgaaaa ccatagatga agagaaagag agaaaggcgg aggttgcagt 9540
gagtcgagat cacaccactg cactccagcc tgggcaacag agcgagactt tgcttctaaa 9600
aacaaaaacc aaacaaaaaa agaatgacag ctgtgttctt aacagaaata atggaaacca 9660
aaagtctatt gaaatttaag tcctcaaaga aagttactgt gaacccagaa ttctgtatgc 9720
agcaaaaatg tccttcagaa aatacagttg aaataaagat actttcatat aaacaaaaac 9780
aatgtttttg ccagcagacc cacactaaag gaaacattaa gtgttttttg tttgttttgg 9840
ctaaaggaaa atgctcaagt taagcgttag agttacagga aggaatagag acttaagggt 9900
ttctacgtgg gaaagaccaa atgattatta actataaaaa ttatgccttt gggtttaaat 9960
tatatagaat taaaatacat gacaacaatg tcctgtaggt tagaaaggag gcaaatagag 10020
tagaactttt ctaaagtctt tccatttcca ggaagaagaa caaagatcca attatattag 10080
acaagtcagg gatgcatgtt gtgtgtaatc tgtgtggtgg ccaccaaaat tgtgatagtg 10140
tgtgatagct aagctaaaca agaaaaatag aatcagagat tctaaatctg aaagaaggca 10200
agaaaggaga gaaaacactg aacaattggg acaaagagaa agcaaacagt aagttagtag 10260
actgaaatcc cagtatgtca gtaatcacat taaatctagg tggacttaaa tgctccagtt 10320
aaaatacaga gattgtgaga tgggatacaa aagcaaatcc tgactaggct atttgaaaga 10380
gatacgttta aaacataagg atattaaaag attgaaagta aaagaatagg aaaagatact 10440
atgcaaacac taaccaaaag aaacttggtg tagctatttt agtatcaaag tagattttaa 10500
gggcaaaatt attaataaag atatgctgat aaatgagaaa aagttcattt tggatataat 10560
aatttaaaat ttggaagtaa tgacttcaaa atatatagaa gaaaaattaa cacaattgta 10620
agggaaacaa attcataatc atagtgagat gttttaacac acctgtctta catgctgtat 10680
acatcaagta gacaaagaaa tttgtaaaag tgtagaattg aacaacacaa gaacggaact 10740
tttttttttt tttgggagac ggagtttcgc tctgttgccc agactggagt gtaatggtgc 10800
aatctctgct cactgcaacc tccacctccc aggttcaagt gattctcctg cctcagcctc 10860
cagagtagct gcgactacag gtgtccatca ccatgccacc atgcttggct aatttttgta 10920
tttttaatag agatggaggg ggggtctcac cgtcttggtt aggctggtct tgaactcctg 10980
acctcaggtg atccacctgc ctcggcctcc tgaagtgctg ggattacagg cgtgagccac 11040
tgcacctgcc acaagtacta aacttgacct aatggaaatg tatggaacac tgtacctaac 11100
aattgtagaa tctaagtttt tttccaatgc acaggcacat ttgtcgaaat tcactatatg 11160
ctggccataa cacaagtctc aacagctttc aaaagagttg aaattataga gtatgttctg 11220
acaacagaat taagccagga tcaataaaaa gaaaatctca atgtatttgg aaattttaga 11280
tgtctatttc taagtaattt atgagtcaca gaaagcttaa atattttgag ttgaacaata 11340
gcaaatatgt atatataaaa tggggtacag ctgaagtcat gtttagaggg aaatttatag 11400
cttaaaatac gtatattaga aaagaagaca tgctgaaaat caggtagtta gaagaatagc 11460
aacacattaa actcaaagga aatagagtat ttttttaaag gatttataga agaatgagga 11520
ggaggaggtt gctgatcaaa gaggtatgca aaggccctgt ggcaagaggg agcttgggga 11580
aatcttgggg ctgaaagaag gctgtggtgg ttagggctgg taagcatcgg gagcctttgg 11640
ttgggatctg acactggaga gggttggagg ctgtgttagg gagctctgcc tattttcccc 11700
cagattagtg ggatactatt gctttaagat tttaggaagg accatgacct aattggatcg 11760
tggttgaaaa gatggctcta gctgcgctgc ggttgcctga gtggatgctg gctgacccaa 11820
tgcagtgaaa gatgctggca gcctgggcct gtgctgtggc tgtggcgatg ggggaagtag 11880
ctggatttga gagatgctga ggaggtgaca ttgtgagaac tcagtgatgg tttggtgtgg 11940
gtgttggggg agaggaggtt tgtgattcct gtgatgagct ggataatgga actcttctct 12000
gatataagga gctgtggttg aggacagctt tggggatttt gctgttacct ggctctgctg 12060
catgctatcc tggaacctct tattctccac taccccagtt ttgccaatga acgacataga 12120
ttcagcagtt aggtggcttg ctagtgtgcc atgaagccat gtaggtctca ctgaacccag 12180
atagggcctc ctttgtccct tcctccccag cccccagtca tgcagcagca gtgaggatgg 12240
ttcatctgag cccgagagtg aggacagtgt gacggggtca gggcccgatt ggatgctggg 12300
gccgttggct tttaggaggt gggcagaaga ggaagaggag gactagtcaa agaaggaagg 12360
actggcaggg gaggagaaag aaagggggct gcagagaagc cccagaacca gcacagttta 12420
cctctaaata cctcagtgta tgtctccaca acatgaggat attttcttat ataacaatac 12480
cattatacct gaaaaaactt tttaacattt aatatccaga tcattttcaa atttccccag 12540
ttgaaccaga aatgccattt atgaccttcc ttttgggaac caggtaccca tcaagtttta 12600
cgcatcatct ttggttgttg ttatctcttt agtttgttaa attagaacag cttccactgt 12660
tctctcttcc cgttccctac ctgcctataa catcaacttt ttcaagagac aagggcagtt 12720
gtctggtatt aatgactttt tttttttttt gttcagacag aatctcactc tgtcgcccag 12780
actggagtgc agtggtgcga tctcggctca ctgcaacctc cgcctcccag gttcaaatga 12840
ttctcctgcc tcagcttccc aagcagctgg gactacaggc gcccgccacc atgcccggct 12900
gattttttta tttttagtag agacggggtt tcaccatgtt ggccaggctg gtctcgaacc 12960
catgacctca agtgatccgc ccacctcggc ctcccaaagt gttgggatga caggcatgag 13020
ccaccgcacc cagctgtatt aatgactttt aatggcaaaa acctccatta cttttgtacc 13080
aacctaataa tctttctgga tttttctgat tgttttccca tcattctttt acattgttgt 13140
tttatctcct atatttccta taaagtagaa gtaagcagtt tcaaagactc tcacttctat 13200
attttggttg acattttggg catatcccta aatatggaat gctctgtgct ctaccgcatc 13260
ccacttggag gtgggtgtgt cctgtcaggc tgtccccctc tgctgtgtca tcgcttggtt 13320
tacagatttc taggtctttt cttcctcttt tttttttctt tttttttttt tttttttaat 13380
agaagtggga tctccctacg ttaagccagt ctggtcttga actcctgacc taaagtgatc 13440
ctcctgcctt ggcctcccaa agttctggga ttacaggcat gagccacctt gcctgaccag 13500
atcttttcat tggagatgtg atttcccctt tacagttagg aagtaatagg tgattcctgg 13560
gcactgtgca aatatccttt accccaaatg gtttccatat tcatacacaa tacaggactt 13620
gcctgaagca attttattat aagagttttt aaaatggaga ttcctgccac ccccattgtg 13680
tcatttattc cacatttatc tgttggtgtt attctgtaaa gatattttct tggggccagg 13740
cgcggtggct catgcctgta atctcagcac tttgggaggc caaggctcag gcgatcactt 13800
gaggtcagga gttcgagacc agcctggccg atatggtaaa accccatctc tactaaaaat 13860
acaaaaaaat tagctgggca tcgtggtgga cacctgtaat cccagctact ccagaggccg 13920
aggcaggaga atcgcatgaa cccaggagga ggaggttgca gtgagccaag atcacaccac 13980
tgcactccag gctgggcgac agagcgagac tccatcaaaa aagtgaaaat aaaaggatat 14040
ttgctcactt caaccgagtt aaggaccaca gttcctccta aaaaggcagg tcaattgctg 14100
gattctttgt ttaattacca atgttcgagg taaggatttg gtaaatagtc atccccagta 14160
gaggcaaatg tttctctccc cccaacccta aacccccaca cccaccctga gtatcactat 14220
atggattcat ggcaattttt attcagtgtt ttacaatcag ttacagtcat tctttttgat 14280
gctaaaatta tcctgatttt cctggaaaca caccttcatc tggctctttg gtctttaaag 14340
gcttgcttgc tatgttgcga tctgttttca tcttctggat agagtcctgg agctggagtt 14400
tcaggtagaa gggacagtgt gcgtcctgtg gccgaggctg ccagcccaca gcgtgcattg 14460
ctgcccattt cctgccagtc ctgggacgag agtgcctagg agtttcaaga tttcaggctg 14520
gcaggtcttt gttttccttt tttggattgg cttaggttta gggttgtctc agcctcataa 14580
agtgagttgg gtagctttct gtgaggaagg cttttgtctc tgcctctcat attgcatctc 14640
catttatttt attttttggg gggaggttct catctgtagg ttagaccatc tgtctcctta 14700
ccactctgtc catctcagta tttttccctg tccactgtat ccatcagcat tctgggggcc 14760
tcagttttgt ctttttgcca ccagtgacat tttctgtaat gtacattttt ccctttgact 14820
ccttccagtt ggattttaat ttttccgtag tgtgattgtt tttgttttct aatcttggtc 14880
agcatcttag cttgttgtct tttaatttca acctattctc attttggtgc tccctgtctt 14940
ttaaaaacat tttaatttta actttttaaa taaaggccac gtcttcctgc atcttaggac 15000
aagaatcaca tcttttctaa aatggtcttc cattttctgc aatcattcat ttcaggtttg 15060
tgcatgtact ttatggcatg tttttccatc agcctctccc ctcccccttt ctgttctgat 15120
gtgatgttcc ttgaatggcg tttgccaggc tgcgggtttg aattgctgtt tcctggggac 15180
ttggctgggc acaatctggg gctggccgtg gggtgatcgg ccacgggccc aggctgtgtc 15240
tctgctgctc tgggcgggct ctcccctcac cttgaattca tgtgcaatgg ccccattttc 15300
cgtgtccatg tgtgttcctg agtagtgggt gtttgctgat cacctgctgc ccactctgct 15360
ggctctgctc ttctgtgtct gagggtaaag ggtgtctgcc tccctttccc ctgcaggaag 15420
ggctggactc tcatcccctg atgaatggtg ctttgtcctt atagaatgat ggaagaggga 15480
cactcttttt cttttaaacc tgctatttta accattttaa agtgcacagt taagtgccat 15540
taagtacatt aatggtattg tgtaaccatc acctctatct agtttgggaa cttctgtatc 15600
ccctacatgg aaatcccttc cccatcgtga gtcactcctc atttccccct cctcccagct 15660
gctgacaacc actaatctgc tttccatctc tatggatttg cctattctgg atatttcatt 15720
tattatttat ttatttttta gatacagtct tgctctttct ctcagggtgg agtgcagtgg 15780
ctcaatctca gctcactgca atctctgcct cccaggttca agcgatcctc tcacctcagc 15840
ccccccagta gctggcatta caggtgcact ccaccatgcc tggctaattt ttgtattttt 15900
agtacagagg gggtttcacc atgttgtggc caggctggtc tcccaattcc tgacctcaag 15960
tgatctgacc gccctggcct cccaaagtcc tgggattaca tgcgtgagcc accgcacccg 16020
gccactgagc actgtgtttt caaggcttat ttacgttgta cgtttcagaa cttcttcttt 16080
tttttttttt ttttttgttt gagtgaataa tactctgttc tgtcaatgta ccacattttg 16140
tttgctcatt catcggttga cagatatttg ggttgcttct accttttgac tattgtgaat 16200
agaactgctg tgaacattca tgtacaaatt attatttaaa tacctatttt catttatttt 16260
gtattttttt ttaaattttt gagacagggt ctctgtcacc caggctggag tgcagtggtg 16320
cagtcatggc tcactgcagc ctccacatct tgggctcaag cagtcctccc acctcagctt 16380
cccaagcagc tgtgactaca gatgtgtgcc accatgcctg gctaattttt taattttttg 16440
tagagatgag gtcttgctgt gttatccagg ttggtctcga acactcgggc tcaagtgatc 16500
ttcttgcctt ggcctcccag agtgctggga ttacaggtgt gagccactgt gcccagctga 16560
cctgttttca tttcttttgg gtacgtacat gtgagttaaa ttgctggata attctgtgtt 16620
tatcttattg aggagctgct aaaccacaaa ggctgcacca ttgtatgttc cctccagcag 16680
tgcatgagag ttctgatgtt tccacacttg ccaactcttg ttactttcca cttattataa 16740
tataaatgtt ataatattta ataatttaag aatattatat tattcagttc ctcaatgact 16800
aacaatgttg agcatcattt catatgttta ttgaccattt gtatatattt tttgaagaaa 16860
tacctattca ggtccattgc ccattttcca atcgggttgt cttcttgttg ttgaattgta 16920
agagtttttt atatattttg ggtactagaa ctttatcaga tacatgattt gcaaatattt 16980
cctctcattc tgtgagttgt gttttcactc tcttgatagt gtcctttgag gcacaaaagt 17040
tttgaatttt gatgaagtcc aatttttttc ttttgttgct cgtgcttttg gtgttatgct 17100
taagaaacca ttgcctaatc caaagacaag atttatacct atgttcttcc acgagttttg 17160
tagtttcagc tattattaat atatttagtc tttgatccat tttgagttat tttttgtatg 17220
tggtgtgagg tcaggttcca acttcattct tcctgtgtgg atgtgcagtt gctccagcac 17280
cagctgttga agaggagcgc tctccagttg gagtctgcct ccccagctgt gcagacagcc 17340
ctgcagtatt gaaaaacagc cacagagctc ctcaggagtg cttggaaatc tcaatggagt 17400
tcataaagtg attcttaata gaatcattct tatgtatggt tatgagacat ttacatattt 17460
aaagagttta aaaggaagta tctgcatttc agaattttta ctgccatgga actcatctac 17520
attttatttt gttttatttt atttttttca gacaggatct cactgtcacc caggctggag 17580
tgcagtggta tgatctccgt tcactgcagc ctctacctcc cgagctcaag tgatcctccc 17640
agtcagcctc ctgagtagct gggaccacaa gcatgcacca ccacacctgg gtaatttttg 17700
tattttttgt agagacgggt tcttgctatg ttgcctaggc tgtcctcgaa ttcctgggct 17760
caagcaatcc gcccgcctca gtctcccaaa gtggctagga ttacaggcgt gagctactga 17820
gcccagcctc ttctacattt tatgtttgag aatatggact tgattcagtt ctttttatag 17880
tttggtaaac ttgaaataac actcatctca ttaaatccag tctcatttga cattctcagt 17940
atttgaactc tgataaaaat ggactagtac tcagaagctg ggcagaaggg aagtctgaga 18000
agttgttctc tatctccttt ctctctgtgg ttgctgaaca tttttgtgtg cttcaagagg 18060
gcaagtagaa ccaggtttgt caagaattaa gacataagtc tttttttttt aatttttatt 18120
ttttttctta catttaaggg agatctggcc aatgtgtatt tttattgtcc attagtcaca 18180
attgtctgtg tttttatatc taactagtgt tttgtattat ttgctgtttg tagaaactcc 18240
ttggtagtta actgcagctt ctttgtcctc tggcagcaga aatgggtata accatttggg 18300
aaagtgactt agtgagtgtc tgaataactc caagagactc ttggtccaga attctaacac 18360
tgggactcta tcctgagaaa ataatcttaa atataaagct catgaacaac atgtttattg 18420
taccattaaa tataaaaagt tgcaagccac cccagtgtcc aagtccagct taggacaaac 18480
cccaccagaa cactccagtg taatgactca gtgagttaat gataatagct gataaaatgg 18540
gtactgcggg cgggtcccgt gctgtgctct gtgcgcgtgc tgtcccactt caccttcaca 18600
acttcatggt ggctgcacca ggtcacaaag ctggaaagtg gcaatgtgca tggctctcaa 18660
tgcctgaagc tgccagccag gtaattgagg aggtcagcaa cagggacggt actatgtgat 18720
gttggagaaa taaagaggcg aagctgtgtt tacagaatgc gtttcagcag tgtgtaaaac 18780
actggaaata agatggaata ggaaataaca cggaggaagt ttcttatgat attgtgggtc 18840
gggttaggtg gtgagatttg tattattttt atgtttacat ctgcttgcct gcattttcta 18900
aaatgagcat gtattatttt ataccaaagg aaacaaaaag gcataacatg cttcccgtca 18960
atggaagact cctaatggta agaggggctg tgttgtgacg tggagatgat tcagattgga 19020
gaagcagctg ccctcagcct tatctggaat gtcctaaaac agctgaaacg atactgttgg 19080
atcaaaacag attgaatttc aggagtcaaa tatacaaaag ggcatgcttg tgaaaataca 19140
ggatttaagt ttcataatat cctaataaat gggtacatta tatggaacga cttaattatg 19200
ttcccccttg tttgaacttt caactcctgt gttgaaatta aatctacact tacctaagaa 19260
gtgagctcaa ggtcttgata tgaataggat gtattttagc ttgagatgta aactgtttga 19320
tgcgtgcaat gttatcagtt ctttagataa tgttcataat gacattagca tccctaaaca 19380
tttgaataaa tgaaaaagaa ataacatata gaataataat acacaaagta aaagcagatc 19440
tagttgcagt atattgttgt ttggaaaagc aagttattga ataatttgta catcatgtaa 19500
ctccccttta tgtcttttag tttaattttt tttttttaca cagggttttt tttgtttttg 19560
tttgtttgtt tgtttttgag atgaagtctc gctctcaccc aggctggagt gcagtggtgt 19620
gatctcggct cactgcaacc tccacctccc gggttcaagt gattctcctg cctcagcctc 19680
ctgagtagct gggattacag gtgcctgcta cgatgcctgg ctagtttttg tattttcagc 19740
agagacaggg tttcaccatg ttggccaggc tgattacgaa ctcctgacct caagtgtgcc 19800
ttctgcctca gactcccaaa gtgctgggat tacaggcgtg agccactgcg cctggccttg 19860
acacggggtc tcgccctgtc acccaggctg gagtgcagtg gtgccatcat cactcactgc 19920
agccttggac tcttgggctc aggtgatttt cctgtcttgg cctccccaga ggctaggact 19980
acaggtatgg gccaccatgc ccagctaatt tttagatttt ttgtagagat ggcatctcac 20040
cgtgttgccc aggctggtct tgaactcctg ggcacaagtg atttgcccac ctctttctcc 20100
caaagtgctg agattacagg tgtgagccat agcacctgac aattttattt ttacattttt 20160
ctttttagag gcacggtctt gttctgtcat ccaggctgca gtgcagtggt tcagtcatag 20220
ctcactggag cctaaattcc tgggttcaag caacttttct gccccagttt ccttagtagc 20280
taggactgca ggcgtatgcc accataccca gccaatttta aaagttttta tagagataga 20340
gtctctataa aagcagaggg atactttact atgctatgtt gcccaggctg gtcttgaatt 20400
cctgggctca agtgatctgc ctgcctcgtc ctcccaaagt gctgagatta caggtgtgac 20460
ataccatgcc cagccccact tttctgtttt atttacacac ttgaaaacag atggagccgg 20520
gcgtggtggc tcatgcctgt aatcccagca ctttgggcgc ccaagtccgg tggatcaccc 20580
gatgtcagga gttcgagacc agcctggcca acatggtaaa atcctgtctc tactaaaaat 20640
aacaaaaatt ggccaggcgt gatggcacac gcccgtagtc ccagccactt gggaggctga 20700
ggcaggagaa tcgtttgaac ctgggaggtg gaggttgcag tgagccgaga tcgtgccacc 20760
gcgctccagc ctgggcgaca gaatgagact ctgtctcaaa aaaggaaaaa aaagaaaaaa 20820
aagaaagaaa acagatggga aggatgttat ctcggcatgt gaatagtagg tgttagcgtg 20880
gctgggctct tggtggtctt aagtaaataa aaagtaacct ccagcaaaca agtctgccat 20940
gagttgggcc atttaacaca ggactttatt ctccaaatgt cagaaaacag gtgaggaagc 21000
agctggttga gcacatgcca ggggagagga ggttgaatgc tgatagtggc agcactgccg 21060
cattgttctc aggtgctttt ctgtttggtg ccttgccctc tgaggtggga tccataggtc 21120
aggaagctgg ggaggctgcc tctagtccag gcagcaccag cttcaggcct ctggtgtgtt 21180
tcactgactt ccaagtttcc aaagcgccct gtctgcaccc ctcttatgac acttgaaaac 21240
aatttatgga aatttccaag cagacacgga agtagagacc gttgaattaa tcacatcagc 21300
ctgtgtcttt cttgtttcat ctgtctccac cccctaccca cacccctact tttctcctga 21360
gcattttaaa gcaaatactt ctggttcttc ctactgtcaa gtatccctct gatggagcag 21420
tttcctgaaa ggtcaagggt cgagtccctt tcactgtagt attgcaagcc acactcagca 21480
ctcaagtgtt caataaacat ttattgaaac agagtgattt cattccacag ctcgataggg 21540
agatggattt tgttctgtag gtttcgcaga agctgaatct ttcctacctt aatgaaccac 21600
agagcgcatg tgtgtatttt gggatgtcgc acctgctgct gggggttaag gtttgtttcg 21660
cctttggtgt gtagtggaga tgggtttgtg cataaattca ctttcagaaa aagtagggtg 21720
actggttatg gctataattt agtctgaact tgtacagaca aaaataatga aaagtaaatc 21780
ttccccagac ataaaaaatg tttttcattt gctgtctaag catggagaga gttgaaatca 21840
gacagatctg ggtctgaagt ccacatctgt cacttcactg tagatgtcta tgtcctctct 21900
ggaccccaat ttcttcatta gtaaaatggg gctataacta ttgtatgggg cagattaaat 21960
acagattcta cataagctcc tggcacatag taggcactcc ataaatactg attatttctt 22020
ctccttgccc atggttctgt gaaatgggaa tgtttcctgg gcctccctta ggaggtcatt 22080
gtatggattt ttttttaata tatatgtttt ttattatact ttaagttcta gggtcctttg 22140
tagggacatg gatgaagctg gaaaccatca ttctcagcaa actatcacaa ggacagaaaa 22200
accaaacacc gcatgttctc actcataggt gggaattgaa caatgagaac acttggacac 22260
aggaagggga acgttgtatg gattaaatga gtaatctttg gaaagtgctt acacctgagc 22320
ctggagcaag tcagagctca gcctcctggg tgctgctgcg ggtgctgccc ctgtcctggg 22380
agtcctttta aaatcatgtg tgtgccttcc ctgtctcatc taccctgttc cctttcccta 22440
gaggtaacca cttaaccatt tttattatta ttttggttaa tccttccatt gtttcttttt 22500
ggaaaaaaaa aactaagttt atcttcttca cacacaaaca atgtcctcct ttttacaaaa 22560
agatattaat agcgtagcat gttccttttt tttttttttt tttttggaga cggagtttca 22620
ctcttgtcac ccaggcagga gagcaatggc acgatctcgg ctcacttcaa cctccacctc 22680
ctgggttcaa acgattctct tgcttcagcc tcccgagtag ctgtgattac aggtgtgtgc 22740
caccactccc agctaatttt ttgtattttt agtagagacg gagtttcacc atgttggcca 22800
ggctggtctt gaactcctaa cctcaggtga tccacccgct tcggcctccc aaagtgctgg 22860
gattacaggc gtgagccact gcgcctggcc ccttaatagc atgttctatg catgttctgc 22920
acagttatct ttttacttgc tctgatttgg agaggttccg tagtgtataa aaatatcttc 22980
cacaatcctt gtatagttat atggtactcc atattttgaa tgtaccgtaa tttattcgac 23040
cactagcctg ttggtgggta tttgggttat tttcagtgtt ctgctataat agtttgtagc 23100
acatagcctt gtacaaactt ttttttctat tttgccaaag tgtcttttgg gatagattcc 23160
taggagtggg cttgctagat cagaagagta aatgcatgaa taactgctct ggattttgcc 23220
aaatgtttgt cttcagggcc atcccgtttt gcagtcgtgt tgagtgcctg tctccccgtt 23280
gccatagaag cagaatgtgt tgcctctttg gtttttttgt ttgtttgttt gttttgagat 23340
agagtcttgc tctgtcaccc aagttggagt acagtggtgc gatcacagct caccgcagca 23400
gcctcgacct cttgggctca ggtgatcctc ccacctcagc ctctcaagta gctggagcta 23460
taggtgcact aatttttaaa taattattat tattttttgt agagacaggg tctgtgttgc 23520
tcaggctggc cttgaactac tggtctcaag tgatcctctc acctcagcct cccaagtagc 23580
ttggaccaca ggtgtgcacc accacgccca gctatttttt ttttttttct aaatttgagg 23640
ccgggtgtgg tggctcacgc ctgtaatcct agcactttgg gaggccaagg cgggtggatt 23700
gcctgagctc aggaggtcga gactagcctg ggcaacatgg tgaaacccgt ctttactaaa 23760
atacaaaaat tagctggatg tggtggcggg cgcctgtagt cccagctact caggaggctg 23820
agacgggaga attgcttgaa ctggggaggc agaggttgca gtgagccgag attgtgccac 23880
tgcactccag cctgggcgat agagtgagac tccatctcaa aaaaaaaaaa aaaacttgta 23940
gagatggggc ctcactgtgt tgcctaggct ggtctcaaac tcctgggctc aagctatcct 24000
cccgcctcag cctcccgaag ttctgggatt acaggcgtga tccactgtgc tcagccttgt 24060
ttgttttttg tcagtctgat ggtgcaaata gtattttcac ttagttttgt ttttctcttc 24120
tgagctaggt tgagcatctt ttcctttgtt taagcgcctt ttgcattttt ttctgtcaaa 24180
tgttttcata ttttttgccc ctttttctac cagattttta gtctgttctc aatttttata 24240
atttctttaa agattaggga tattagccct ttgtagtatt ttgtaaaact tcctggcgag 24300
gtgtagtggc ttatgcctgc aataagggag gccaaggcct gaggattgcc tgagcaacat 24360
agtgagaccc cgcctctaca aagcaaagca aaacaaaaca aaacaagcgc acctgtagtc 24420
ctagctactt gggaggctga gatgggagga tctcttgagc ccaagaggtc aaggctgcgg 24480
tgagctgtga ttgagccact gtagcccagc ctggttggca gtgtgagaac ctgtttcaaa 24540
acaaaaacaa aacttcctga ggcactggcg tgattaagat aaataaaccc actgaacctg 24600
agggactgtt ggtctgggga gggagacagc ctcataatgg atgttcatgt acttgcaaag 24660
cggtgatagc tagttctgcc tggggggagg tgatagctag ttctgccttg ggggagtctg 24720
ggaagacttc ccgaaggtgg tggtatttga cttgggtctc aaagcttagt catttcccag 24780
ccaagagaag aggagctgag gatttccagg cggaggaaag agtatattca aaaaagtggg 24840
gaaataaaag gagttggttg tgtttgggtc aggtggttct gggaggggtg agagaggagc 24900
ctctcagatt gggaggagcc cggtgggcca cgtgaagcct tcctagatga caaggaaagc 24960
aaggagaggt ttgggagtgg gccctggctc tgagactgta tgcttcttcc agtcacctgg 25020
gagtttttaa cactgtggct ccctgccccc tcccacactg atgctcatca ctggtggggt 25080
ggggccagtg gtcactgttt ctcaaagctt gtcaggtaat tgtagtggca gttgggatga 25140
aatcctcccg ttgagagaat tgtggcagca ggttggagga aggatggaca gagaacaaac 25200
ttggtgtgct taggaaccac ctgggctctt ggcaaaaatt catatttcca aggctcagga 25260
ggttgggagt ggagcagtaa cttgcttttt ctttactttt ttattttatt ttatttctat 25320
attattattt taataacctg tattttgttt ttagagtagt ccagtgaagt agtgagaatg 25380
gggtagagaa tagagcaagg agttcagtct gtaactgatt gtgaaccatc gtttgagata 25440
gctcactgcc ttcaggccag cggtaacctg catttttaac aaacgttcca ggggttctga 25500
tgtggtggtc tgggtcacac gttgagaggc actgaggcag agacaagagg cagaacaact 25560
taagcctgag gtaggcggag ctgaagagga ggggcagaat cttccattat tttaacaaat 25620
acaatcaatg atcctaggta ggcaattaga aatggggagt gaaggaggaa aagagttgag 25680
cacctgctac ttcttttaga tttgatgatg ctattaatat taactaaaga ggaaacgtgg 25740
gggtcagtga acagtgagat gaggtacatt tcagtgtgga ggcctggccc ctggggacgc 25800
cagcctgcaa gactaggttg gattagcagt gatgctgaca gagcgggagt gaactcagcc 25860
aacccatcgt tatcagacag gaatgcattt ggctgtaggt tgatgtcatc aggacccaca 25920
ctggctacct tgtggcctca gcatggctgc tgcagcacta aatgttgtat gttcatttaa 25980
agcaaaggtg gcactgagac tacacgtgtt cccatatacc agccaagcac ttgcctacct 26040
ccccaccccc aacagaactg cttaggtctc cttgaccagt actggggcag tggggattag 26100
ccctatgatg aaaggtcccc cgcgaccacc acccccagtt cagaaacaag gtcctgtgag 26160
cagtgaggat gtgtgtgtgt gtgtgtgggg gggtgttaac accacatacc gcagcatacc 26220
gcagtaagag aagcgtcctg gctttaggaa agtgggtgtg aactccaaat gaggggcaga 26280
cctggagccg ctctcctggg ggtttgggca tacacatcgt tgccactttt tggctttttt 26340
gggtttggtc cttcctcaca ttagtggggg caggaatgag gtgtctctcc tcctgtcggt 26400
ggaggctttg gcataggagc tttgggacat ggtcgttttt aataatcctg gtggcagtgc 26460
attgaaaacc agggtagtgg caatggggaa attggattct cttgatgggt aagggaagga 26520
tgactgtcct ttttccatga gttggtgttt tggagtcttc agaaaaccta tgttgggttc 26580
ctttctgtca gagttagcac cagactcagg gcctggctct gcagagctga gcgggattct 26640
gcagtgcggc agttgcccgg tgcgctctct cctgctggcc gttggtgtca tgaagacgct 26700
gatgtggcac acactccgtt gccaccttgg gcgtgcacac tccctcagct tctgccagga 26760
tgcggtaaga tcagcttata ggtagacagg tggtgggtaa gttgcaggta gttcctgaat 26820
gaggatgaat ctgtgggtag tgttttgagt agatacagga atttaccttt gcttaattga 26880
tttaaatccg ttatcagcag acttttatgc tgaagtttta ttttgccaac aagtattatt 26940
gtctgggctc tggtgtgtca ttcattagcc aagtggcctt gggtgaatta cttaatcctc 27000
tggccctcag tttcgtaatg tgtaaagtgg gaatattacc accactttca aaattggtgt 27060
gaagattaaa agatgaaaat ggctcctact tgggtagtgg ctgtggtatg tgtgaagaag 27120
tgttggagat aacctggagg tctttgaata tgttttgcat gccttacgtt ttgtgaacaa 27180
attattttct gattgcttcc tatatgtgaa tcatggtgct tgtaaactgc aaaccacaga 27240
tgaagcttta gagatagaat tggagaggcc tgggatttct tttgtgacct gtcattagtt 27300
gttcaaccgg gcaagttact cagtctctct gtttaccagt tttcttattt gttaactgga 27360
atactagttt ctgtctcata gaccagaagt gtttgttctg ttaagaagac aagtaaatat 27420
aaaaatactc atgaaaattt aaagtgatat gcaaattggg ccaggtgcgg tggctcacgc 27480
ctgtgatccc agcactttgg gaggccgagg tgggtggatc acccaaagtc aggagttcga 27540
gaccagcctg gccaacatag tgaaaccctg tctctactaa aaatacaaaa aattaaccag 27600
gcatgtagtg cgcgcctgta atcccagcta ctcgggaggg tgaggcagga gaattgcttg 27660
aacctgggag gcggaggttg cagtgagcca agattgtggc actgcactcc agcctgggcg 27720
acagagcaag actctgtctc agaaaacaaa caaacaaaga gatatgcaaa ttgatagaaa 27780
taagtttacc agcttctttc cactgaaaca tttgtatgtt aattttttat tccagtattt 27840
ccacttttgg ggggctttgt gaatttgggt gatgttgctt aattaaccat agtcaggttt 27900
ctgttttacc tgcttttttg ttgttgttga aggaccgggg aagtctaaag gacagatagg 27960
tggctgaagt ggacatttgg ctaattttct ttcctttctg ctactttttt tttgtttccc 28020
tccccagttt cccagctgtc tgcctgcagc ccctctgtcc aggtcacctt gggcaggctg 28080
tggcttgctg ccctcagcct ctggacacga ctcttggtca gtcccctcca ttttcttcac 28140
ccccacgtgg cagctgtttt tcatttgttt gtcttttact gcgtaaatgt ggaaatcctc 28200
actccttaca tgctcaagac attaacacta atagtctgag attttacttc tatccttata 28260
ttgattaact atatttttcc ctttaccatt ttacatgcag aataatacat ggagtataca 28320
cataagttgt gaagcacagt cacggactgt gcacacgtgg acccacctgc gcggctgagt 28380
gccagggtgc tcttctgtgg catcctccag ggttaagcat cctttggggc ttagtctcca 28440
tttgacttac tcttctggta aatgccggtt cacacttttt acctattttc tctttggtgg 28500
tttttctttt ttatcattcc gtgggagttt ctttttttct ttctttcttt cttttttttt 28560
ttttgagagg gagtttcact cttgtcaccc aggcgggagt gcagtggcat gatctcggcc 28620
cactgcaacc tccgtctgct gggttcaagc gattcttatg tcccagccac cgaagtagct 28680
gggattacag gtatccgcca ccatgcccag ctaatttttg tatttttagt agagacaggg 28740
tttcgctgtg ttgcccaggc tggtctcgaa ctcctgacct caggtgatcc acctgcttcg 28800
gccttccaaa gtgctggaat tacaggcatg agccaccgcg cccagcccgt tccatgggag 28860
tttctgctat attctggtta ctggttactg actggctgtc agcagtagtg tacctttttt 28920
tcccaccttg gcttttcttt tatctctttc tgaggtgtct ttgatgagca gaaattctca 28980
attgcaatat agttgagttt agcagtcata gcttatatct aatatttttt tctattacat 29040
ttaagaaact cttcccaatt ccaaagtcat tggaaattct ctgtcgtctg ctggacgttt 29100
tgaagttctt ctgccttttg ctgtagcgca cccagagtct gccaggagct cacgcgtgtg 29160
gtgtccttgg ctaacctgcc atctcagccc ctttgctgaa gtccccctcc ctcccaaacc 29220
ctggtttgca gtgctgcctg ttacacatca agcttccaaa tctgcaaggg tctgtttctg 29280
ggctatcttt ggtccccaaa ttccgcttct cttaatttgc tttaaggata gttgaggaca 29340
taagcagata tttacttacg ggaatatcca ctgaagttct gatgatagca ttgagggaac 29400
gggaagcatt ctaaatgttc cggcagtggg aagcaggtga atgatggagg ggagggtgtg 29460
taggtgccgt gagatactct gtagccggta aaaatgcatt tgctgatgtg gctatatggt 29520
gataatatac atgacaaaaa aatagcaagg tcacataaca gtatgtacag tatggattcc 29580
acgttcataa aaagaaagtt gtaagttgaa aaaaacctgt tatcttgctt tctcctgtcc 29640
tggtcacact cagggtgatt tgatctggct tcgaccccat caggccacca tgtccgctct 29700
ggcaggtcct cggtgacccc ctggtggctg cttcctttat cctcagctca gttctcattt 29760
atgacctcgc tgctgcattg gacatcactg atgcgatctt ctcgacgtgc tctctgctct 29820
cctccgcttc tgcccacttt cttcttgttc tcctttctgg ctttccttcc ttggtattgg 29880
tgtccctggg ttcccatttc cctgggcctc cgtgtactcc atgctttctc ctttggggcc 29940
cttggcaagg catctcctgt gttaaaactt ctacatcaca gacctgcaga gctggccgtc 30000
gccttacact gaactcccct gacgtcctcg aggcccgcag agtcagcaca tccagaatga 30060
aacccacatc cccccactga gccacactct ttggaggcat ccaggatttc tgtcctgtct 30120
cctccccttc gcctcggtcg attctcacat ctttctgaac attcccatgc ctgtgtccat 30180
ctctcccctg ccaccccaga ctcttgtcat cagctccccc cttatgcgag tttctggagt 30240
gttctgccag cctccacatt tcacccctct tctttcccac actgtggcca cagtcagctt 30300
tccagagtgt atttctgagc caccaccggg ctctgtctgt agccccaggg agcagctgcc 30360
ggcctctgct tgcccagccc ctcctccctg gcctgctcag gtacctgttg tctcaggcag 30420
ctcccttatg gggcattgct cactgccctg tgccccacat cccagagcac tctggtgtgt 30480
acacatccgc cttcctctgg tctgagctcc tggccatgca gccctcagag cccagtgtag 30540
tgaccagcat ctggtgatgc agccacgtgt cagagagggg gcaacctcac cctgtgcttg 30600
ggcctgctag tgcctttcag acagagtcca ttctggactt tccctgcctc ctggtttgaa 30660
gcccttttca aggacattct cagagctgtc ttactgttaa gcaaggacca ctggagactt 30720
gcgcttcccc ccaagcagct gcacgtggta gtcttggacc tgtgggctgg gcatatgtct 30780
gtcgggtcag tgggtggccg tggaccacac tccagctcag gcccagtgct ctcgccaact 30840
tcctctgggg agcccagcac tgggattggt gtcttgcctg tgtttgctgg tgggcgcgtg 30900
ttcactttcc acctgctgct ctctgactgg agcttaagag ttttctcggt gctgtgtgtg 30960
ttgcaaattt gtctctgatt ggaataaggg tatcttagat ggcttgaacg acagttggcc 31020
cttttgtttg tgcatagaac ccaacaaagt gactctaaga gcccggtggc ccggcatggc 31080
ccgagcgaac tgtgcagggg cctggccctt tcactcctga ctctgctcta gggggcaagg 31140
agaggcctcg tcagcctagc agcatttcct gtgggtgcct ttcacagctg ccacgtgcaa 31200
aatacagcac attattttgg ggtgttattt tcttgaccac ttttggttca ttgcttttga 31260
ctaaatgttt aaaaatattc tgcagcatat ctatagtact cacaagcagc gaatcaggag 31320
aagaaatgca gtttctgaga aggcttcaaa gaaataatgg tctttatctt ttccccagcc 31380
ttttccgctg aaacccacca gtctttttct gagcactctt gttataaata aagcagcagc 31440
tctccttggg cagcccaaga tcgcagactc tcatccgccc tcagaaagat tgtgcgtgtg 31500
cgtgtgtgtg cgtgtgtgta agtatgtggt gcagtgagtt gtgttttaat tttgcttttc 31560
ttttatgtat gagatgtgta gcaggagatg caagaaaaaa tactccagca tctgtccttt 31620
aaagataact tataactttt ctgggttttg ggttgttggt tttgtctttt ttttttttcc 31680
catttaggga agagatggaa gtgattgctt tccccacaaa ggtaaggaag atgaatgggg 31740
ggccaggaga gacgtcttca cagtgaggcc tttgaggtca acagagaaag ggtctcgtgg 31800
tatatgtttc aggcttccat ggatggcatt gttctgtgca gatgtatttg aaatgagttt 31860
catccatgtg tacttggatg tgaaaaggat gtttggaaac aaataccatt tcccagtcct 31920
tcacactgaa gactggttta tatcctcgct accagaatcg gggtgggact ttctgtctgc 31980
cttggatcac ccttggtctg ttttggacgg gacctcagat gctaactgta tgctggggat 32040
ccccgctgtc tctaggggag ggggtggggg tggggaggtc acttctggca aacaagcgtc 32100
atcagaatgc ttgatcgttg gataatgttg ggctcctctc tttttccttc ctggcactct 32160
ttaattactg gggagagggt gggtgccttc ttcagaagtg tgaggtgaat gtataagcca 32220
agaatgagtc agtagattct tcagcagctc tgccctgcgc tgatcctcta gagttggaaa 32280
gggctgctgt tgtgccactg ggtcagtgcc aaaagcagag ttcaccatga ttggcacatg 32340
ctggtgagca agaagctctt ggaagtggtc gtgagtgcag ccagttcccc ccaacccagg 32400
aagggcacag tgaggatggc tggttgcggg ataaggagaa gagaccccta ggcagtttgc 32460
attggcctgt gctgtccggg tgtggtcctg gtgtccgtcc acatgttgat ggcgtgtcgg 32520
gctgggggct ttctgcagcc ttccctgttc cactgtctct cctgttgtga atgccggtgg 32580
atggaacagg cagcgcagtg ttctgcgctt gcattctggc ataggtgggg gacatgagcc 32640
tcctgtgtct tgcttttgct ggttttatct tagggagttt taagtgtttg tggatactta 32700
agaactttgt acatgcactg tttgaaacat ttacgtaaag tgcagagcta tatgagatta 32760
ggtagttaag caaaagcttc tctgaaccaa tgtgcttgtc tttgaacaga atttttagga 32820
agcctccctc catttccatg ctgaggctcc ttgtggactg ggcatttccg tgaggtggga 32880
tgtaacatag tgtgcgaacg ccgagagcca ggttcttgtc ttcatgcttg tcgtttattc 32940
tttttgattg tgttaatggc tccgagtacg tcaaaacatc tcatgaccaa gtagttagtt 33000
acgcatttga tgttttggtg gcatgggctg cgtaaggcgg gagagcagct ccgggagaag 33060
tagagccccc ttcattcttg gctttaattg agccaagatg agtggaccgt ataatccatt 33120
tctggattct cgtaagagaa cgtcttgtgt tggggtgaac tcatcagctt ttcgggttga 33180
gaggagtttt agtgtctgtg gccgaggcac tttcctctca tggtgtgtgc agatgcacac 33240
gccaggcctg tgagtggtgg gttgggctga gggcgcgggc ctggagcttc tgagccccag 33300
agccgctgac gtagacagct ttggcagcag catcctgaga aatggcaggg ggccagagaa 33360
cacagagaca gggccaagaa tagctgaaaa ataccaaatg ctgaagttgg agaatgcact 33420
ggccccgcgt cccagtgtcc tcccagctgc tgtgtactgt ggccctgtga gcctcagtgt 33480
cccttcttca tgtctgccag tgcgtccagg gcacaccctg ggcctcttga cacccccacc 33540
cacacaggca cacattgccc cttagaggac aggattggtg caacccccca tgcccccggc 33600
agcgtgctgg gcctgtgcat aggtcaaggt ctgttgagag tgtgagaaat attttctgtt 33660
agagacacga atatgtttca gccgcaacag gctgcgtttc agccggaaga gtgaaagggc 33720
accttgaaaa cgcaagttta tgaatatgtt tctgtacttt cagaccatca tcaaagaggg 33780
gatgctgacc aaacagaaca attcattcca gcgatcaaaa aggagatact ttaagcttcg 33840
agggcgaacg ctttactatg ccaaaacggc aaaggtgagg ccccatgcag gaaagcacac 33900
gcgaggacat cacaggagcc gtcccagggg aggaactggg ggtgctgagt ccttgtgtgg 33960
gaaaagcttc aattctcaga tctgttattg ccagtgagtt ttgtaacact ccacgctgtc 34020
aggttttact tgtctcaagg catgttttat ttcttatcaa aattaatttc tgttcatttt 34080
ccttttcttt aatgtcatcg gtaatgggga aaaggaaaaa agggtcacag agacagccgc 34140
gttacagctg gatatctctc tctcagaaag gcggagggaa tcacggggct atgaatttca 34200
tcttcttatt attaaataat ttttattctt taagtatatt gaagttcttt tttttttttt 34260
tttttttttt gagagggagt cttgctttgt cgtccaggct ggagtgcagt ggcgagatct 34320
cggctcatta caacctccgc ctcctgggtt caagcaattc tcctgcctca gcctcccaag 34380
tagctgggat tacaggtgcc tgcaaccacg cctggctaaa atttttatat ttgagtagag 34440
atggggtttc actatgtagg tcaagctggt ctcgaactcc tgacctcaaa tgatctgcct 34500
gcctctgcct cccaaagtgc tgggattaca ggcatgagcc accgtgcccg gcctagagat 34560
ggggtttcac cacattgccc aggctggtct tgaactcctg acctcaagta atctgcccgc 34620
cttggcctcc caaggtgctg ggattacagg catgagccac tgtgcccagc caaagtagaa 34680
ggagctgagc ttcttgatgt gtgaacagaa atgggaaatt ctttattttt aggctttcta 34740
gcaattaacc ttgtttctgt gtgccctatt gtaggtagat ttaaagctag aagcaccagg 34800
tgggtgctgc tggaggagga gcagccagtg aaagtcacag attactgcca tgtttaagcg 34860
gatgtggtgt tagacattca gacaccagtg tgttggctgg gattctgaat acctgtgttt 34920
tttatcagga ttggtgtcag tactaatatt ttggtattta agaaatctgg agtctgaata 34980
atttacattt tgagacatat ccctagaaag ttactgcatt aaaatttgaa atggaacaaa 35040
gcagcttgtt tagaaagggt tctgaccact tccctcaatt aaaaaaaaaa aaaaacacga 35100
caaaataacc ttttacagtt agttctggtg gtgcggggag gggaaaggtt acttaaaaga 35160
ttgagtttct tttctgagtt attagtttga ttttctccag ggttcctcat agagccatcg 35220
tagaatagag gggatggtat aagggaaaca ggaggcaggg gctgtgccgg gggaccctgt 35280
agggagtgga gagggagacg ggggaggtcc ccaggcctga ctcccagccc tgccctggag 35340
catctttctc tccaggacca ggatccttct gctctactcc cttgtttcct ttcacggcca 35400
gaccctttcc atttggacct gtctctcttc tccagaagaa tttgttttag ccaggacctt 35460
ccccctccat gtgctcgctg gaggaacaag ccaggaggac acggaatcct cagtccagac 35520
cccggccttc cctcagctaa aacactgtgt gagaacatac ttcacatgta aaagtgaata 35580
ctggtattga cagtagtaaa tacagaaata ccagcattgg gttgtttgct ttggttctct 35640
ctctttcttc cttcactaat gcaatgacaa tgtttgtaga tttttttaaa aaaatcatgg 35700
cactatacct gtgagcccga gcttttggtt agaagcaggt gggtgggtta atttggattg 35760
gcttattgat tggatgctac agtttcaagg tactggggct tctgtgggtg cttgttaggg 35820
atcattgggg tgtggtgggc agcgctggct agtgcttagg gatgtacctg tctttatgtg 35880
ccttagtccc tgtgtttgtc tctttctagt caatcatatt tgatgaggtg gatctgacag 35940
atgccagcgt agctgaatcc agtaccaaaa acgtcaacaa cagttttacg gtaagattcc 36000
tcagtcatgc ctttcttgat tcttcactga agttggcttt cctttttgat ctgaacatgt 36060
gtccaagcag ttcaaacgtt ttcattcttt tcttactgat tggaatgatt gctggtaaaa 36120
tttgaattta atgctgaaag taatactgtg gttggagaat aaccaagaat ttggcatgca 36180
taagcacaaa aggacaatag ggaccaaatg aaaaattttt atatgtgttt tggttcacgt 36240
ctgttttgtt ttttttgaga cggagtttgg ctcttgttgc ccaggctgga gtgcaatggc 36300
gtgatctcca gctcacagca acttccgcct cccgagttca agcgattctc ctgcctcagc 36360
ctcccgagta gctgggatta caggcatgtg ccaccacacc tggctaattt tgtattttta 36420
gtagagacag ggtttctccg tgttggtcag ggtggtctcg aactcccaac ctcaggtgat 36480
ccaccctcct tggcctccca aaatcctggg attacaggtg tgagccacca cgctttgctg 36540
gttcacatct tactacctct gtacagagtt ttgttttttg tgattaatgt agaaaatttg 36600
gaaaatgcag acaagtatgt taaagcaatt aaaaagcagc cataacagcc acctcaaaaa 36660
acattgaatg ttaatatttt ggtgtatttc tttttttttt ccttttttat gtttaaactt 36720
tcttccttcc aaatttataa aagttatgta ggactttctg caaaagttct aaatgcacag 36780
aatcatgtga tctcaccact tggaagtggc cagctgctta ctctacagtg tttatcttta 36840
tttctgtata tttatgtctt tacctacatg tacccatgag atcatgctga accttttggt 36900
ttacacctgt gtttttttcc ccccccagga caatttatag tagagagttg ctcatgtcag 36960
ctgatctaaa tgttcatgat attatttaat ggctatagta gcattttctt gtaggatttt 37020
ataatttagg ctttacgggc tgactttagc gcctgcctgt gtaaggtttg actctaataa 37080
cagcactaga acttttaaag ctgtttttct ttatgttatt aggccatccc atgtagacaa 37140
aaagtgtgta ccctaattaa aaaaattatt cttttataat tcagtcaagg tgagtaattt 37200
tcctcaagtt taggatctga tattttgggt tagtgctagt ttcaggtgct ttcaagtttt 37260
gttttatttt atttattgat ggattcattg ttgatgttgc caatacaaat gggattttcc 37320
tttctctgtc taaacctctg cttattttgt gttgattaac tgctcttatt ttacttggag 37380
tatttgtagt tttctctatt aatttatttt taccagctgg gaagagacat ttttaaccac 37440
ataaatagat ttttctttga ttcgtggttt ttagagtctt taataggagt aggtgttgaa 37500
tttctttgga gtgttctgag catcagttga ttaattaatg aatttttttg agatgttgtc 37560
tccctttgtc acccaggctg aagtgcggtg gtgtgatctc ggctcactgc aacctccgtc 37620
tcccaggttc aagggatcct catgcctcag cctccctagt agctgggatt atagtcgtgc 37680
accgttatgc ccagataatc ttcgtaattt tagtagagat ggggtttcac catattggcc 37740
aggctggtct caaactcctg gcctggagtg atctacccgc ctgaaccttc caaagtactg 37800
ggattacagg catgagccac tgtgcctggc cctgggcatt aatttagatg ttcattttgg 37860
tttcagttat ttgcatattt cctaataaaa aaattattct tggtaatgtt gaattttact 37920
cctttatctt gcaatttaga attttcccac tggtatgtat gcatttgttt tgggtgagaa 37980
tgtagcctta ttgcagtttt aaacaattgt tttttctgtt tttaatttta atggatacat 38040
aatagttgga catactgtgt tttgatttca gagttaaacc aaccccataa aattcattta 38100
gtaactttct atgagtttat gttttctgca acattttatg tagctttggg attggttgtt 38160
tcttaagttc gagagaattt attttaaatt atttgtcaag aagacttttt agggagataa 38220
ggctgtaata gaaataaatc ctaaaatatt tatttcttgc attttgatca ttttttgaac 38280
cttttcactt tttgagtcca catctgtaat ttactttccc acaaatttca caccttcaaa 38340
gttagtagcg tgtactgttg tgtagtttaa acacctgtgt ctctggttga atctcctttg 38400
catttctaat tttattagtt tagtttgctt ttcttgtcag atttcgtaaa ctctagcatt 38460
tttgttttct ttgtttttaa agagaactag ttcttagatt attgaacaat tctccttttc 38520
tgtttccttt tttatttttt tgagacggaa tcttgctctg ttgcccaggc tggaaggctg 38580
gagtgcaatg acgtgatctt ggctcactgc aacctccacc tcctgtgttc aagcgattct 38640
tctgcctcag cctcctgagt agctgggatt gcaggcacct gccaccacgc ccagctaatg 38700
tttttatatt ttcagttaga gacggggttt cgccatgttg gccaggctgt tctcaaactc 38760
ctgaccttga gtgatctgcc tgcctcagct tcccaaagtg ctgggattac aggtgtgagc 38820
caccacgcct ggcctgtttc cttttttttt tttttttttt tgagacaggg tcttgctctg 38880
ttgcccaggc tgcagtatag tgctgtgatc tcggctcatg gcaacctctt cttcctgggt 38940
taaagtgatt ctcctgcttc agcctcctga gtagctggga ttacaggtgt gtcccaccac 39000
gcctggctga tttttgtatt tttagttaga gatgggtttt cgccatgttg tctaggctgg 39060
tcttgacctc ctgacctcaa gtgatcctcc tgcctcagcc ttccaaagtg ctgggattac 39120
aggtgtaagg caccatgctg ggccctactt tcctgttttc taattcagtg tctgtattta 39180
tgtgtattgg tttttttttt ttttttttta gatggagtct tgctccgttg cccagggggg 39240
agtgtagtgg tgtggtctcg gctctctgca gcctccgcct cctgggttcc agtgattctc 39300
ctgcctcagc cttgggtagc tgggattaca gacacatgcc accatgccca gctaattttt 39360
ttatttttag tggagacagg gtttcaccgt gttggctagg ctggtctcga actcctgacc 39420
tcagtgccca ccttggccac ccaaaatgct gggattacag gtgtgagcca ccttgcccgg 39480
ctgtgtatta gtttttatct gttgtaactt acgaaatatg ttgttcaagt cctcttatga 39540
tcttgttttt tatcgcttga gcttccatag gctgttaatg aggagttaga atctctttca 39600
ggccagttac gtttaacact ttgttcatgt atttctaaca gttttcacct tctccatttt 39660
gaagctttgt taagcgtgta aatatttaaa aagataatac cttcaatatt gagtaatcat 39720
ttgttaataa agattaataa agtagtagct ttttttttct tctttcctag acaaggtctt 39780
gctctatcac ctgggttgga gtgaagtggc acaattatga ctcactgcag ccttaaactc 39840
ctgggctcca gtgatcctcc tgcctcagcc tcccagttag ctgggactac aggtgcttga 39900
taccatgcct ggctaatttt tacatttttt tgtagaagca aggtctcgct atgttgctca 39960
ggctggtctc aaactcctgg catcaagtga tcctcctgcc ttggcctccc aaagtgctgg 40020
gattaaagaa gatctttttc gcaatgagta gtttgtgtca ttaactgttc tctcatgtat 40080
attagtattt ctaagtcttc ttttctttgt tcagaattta cttgatatac atacccccca 40140
cccttttcca tcctaacttt tatctttagt tttccttatt attttgaatt taattccctt 40200
tttttttttt tttttttttt tttttttttt tagagatagg ctcttgctgt gttgctcagg 40260
ctggaatgcg gtggtacagt gttagctcac tgcagcctca aactcctggt ctcaagagat 40320
cttcctgcct caccctcccc agtagctgga accacaggca ttgtcaccac acccagctaa 40380
ttttttattt tttgtagaga tggggtctaa ctatgttgcc ttggctggtc tctaacttct 40440
ggccccaagt gatctgtctt ggtgtcctaa agtgttggta ttacaggcat gagccgatgt 40500
gccttgccta gatttaattc ttgtaaacag tatgttgtta gaatctgtct tattttagtc 40560
agaaaccctt tgccttgtaa atattgtgct tcagccattt tctgctgtca ggattcttgc 40620
atatctgatg cctgtgtttt gtggctgaat gtattgtgct ttcttgtttg tttgtttgtt 40680
tatttattta tttttgagac aaggtcttgc tctgtcaccc aggctggagt acagtggtgc 40740
agtcatggct cactgcagct tcgacctcct aggctcaagt aatcttccca cttcagcctt 40800
ctgggtagct gggactccag gcacatgtga ccatacccag ataatttttg tttttttgta 40860
gagaaggagt ttcaccatgt cacctaggct attcttgaac tttggggtgc aagtagtcca 40920
cccaccttgg ccttctgaag tgctgaggtt acaggcatga gccaccacac ccagccatgc 40980
tttcttattt taatggtctc ttggtacctc tcttctactt cccttctgtg ttgtctctta 41040
aacatttata gttcacagat tttctttttc ctttcttttc ttttcttttt tctcctcccc 41100
tcccctcctc tcctttcccc tcccctcccc gcttctctct ttttctatct tcctttcttt 41160
cctttttcct tttttttttt taatttaaat ttaagagaca ggtcttactc tgtcgcccgg 41220
gctggagtgc agtggcatga tcaccattta ccgcagcctt gaaatatcag gctcaagcga 41280
tccaccggcc tcagcctccc aaaatgttca gattacaggc atgagccacc atgcctggcc 41340
aagttcacaa attttattat gctagacctg tttgtagcca gcccatatgg tgacatcctt 41400
tttttggtca agctttgtgt attactgagg gtttagtcac agagaacatg ctactcaatg 41460
ctttgtttca ctagctctta ttcgattcat accaaaccat gaaaatgaaa aaggactgaa 41520
gaacatggaa gaaaaataat gcaaaatggt ctgttttcca gaaaggaatc aaatacgata 41580
ttttattagt gagctccgag aacatagtat ttcccaatgt tggtgttgca gggggttgtc 41640
gagagcaggc tcgatgctgt tgctgtcttt gaaggcattt ctgctcggag actcagagtt 41700
gccttctctc ttgtgcaatg cgggtttgct aactggttgg tctgggatag agcaagcctg 41760
atttcttcct cactccagtt tgggctttcc agctttgaaa aactgttttt tccttctttt 41820
ctcttacact tgaaaaaacg aattctggtt catgtgcttt gtcttgttct ttgggaattt 41880
ggctcgttta tttagtcatt gttttggcaa gcattttttt tggggtctac cgtgggccac 41940
acaccatgct gagtgcggtg ggtagaaatg gagaggagcc actctgcatc aagcttatat 42000
tctcgtggga gatcagataa gcacatacat agaaccttag ttacaggctg agacaagctc 42060
cgatggaaga gcagtacatg gtgcctgata tgtggaagac cccacctggc cttggggagg 42120
ggctgggcag tcttctcaga ggaagtgagg tctcatagct gagacatgaa gaatgatagt 42180
ggtaaatcca ctgagggaag catgagcctg agagggtatg tgtgtctgtg tgttggtgtg 42240
tgtctgtgtg tttctttgtg tgtgtctgtg tgtttcttgt gcaaataggc acctcgggga 42300
tggggcaggt ggagggacca gcagtgcgaa gaccttggga tggggacacc acgtggagtg 42360
tgcaaagtgg tggaagggcc agggtggctg atggaggcca gagcaagagg acaccagagg 42420
ggaccagcgt ggctgggggg ggccagagcg agaggacacc agaggggacc agggtggctg 42480
gggggggcag agcgagagga ctccagaggg gaccagggtg gctggggggg ggggcgccag 42540
agtgagagga ctccagaggg gaccagggtg gctggcagag gccagagtga gaggacacca 42600
gaggggagca gggtggctgg cagaggccag agtgagagga caccagaggg gaccagggtg 42660
gctgcggggg gggccagagt gagaggactc cagaggggac cagggtggct gggggggggg 42720
gggtgccaga gtgagaggac tccagagggg accagggtgg ctggcagagg ccagagtgag 42780
aggactccag aggggaccag ggtggctggg gggggggcca gagcgagagg acaccagagg 42840
ggaccagggt ggctgagggg ggcagcagag tgagaggact ccagagggga ccagggtggc 42900
tggcagaggc cagagtgaga ggactccaga ggggaccagg gtggctggca gaggccagag 42960
tgagaggaca ccagagggga gcagggtggc tggcgggggg ccagagcgag gcgagaggac 43020
accagagggg accagggtgg ctgggggggg ggggcagagt gagaggacac cagaggggac 43080
cagagtggct ggcagaggcc agagtgagag gactccagag gggaccaggg cagagcttgg 43140
gacttactcc tcaggacttg ggctgctgtt gaatagtttt atttggtgaa attctcagat 43200
ttgcaggtgt cagaaagttc tactctggct gtagggtgga gggtgaactg gaaggggagg 43260
gaggtttgta ggattgttag gagagagtgg agtggagagt gcggaggtgt ctagggggca 43320
gtgggcaggc tagtgatcag gtcagaaggg ggtggagtag atgaaggtgt cagggcttct 43380
gctgagtaca gcagcaggct ggttaagtga gctcaggagt ccagaagagg ggctgtgggg 43440
tggtggggga ggcttcttta tcttccatgt ctgtcacatt ctttagcctt attttattta 43500
atttgttggt ttttttccta gttctagtta tcaaagtttt tatattgttt gttactacat 43560
ttacttgcaa cctcccctcc cagctcccac cccccacccc cgattttggc atactttgta 43620
tttatcctgg cttattcttg tttgaaaggt aaaatttttt tttttttgag atggagtctc 43680
gctctgttgc ccaggctgga gtgcagtggt gcgatcttgg cttactgcaa gctccgcctc 43740
ccgggttcac gccattctcc tgcctcagcc tcctgagtgg ctgggagtac aggtgccgcc 43800
accacgcccg actaattttt tttttgtatt tttagtagag acggggtttc acagcgttag 43860
ccaggatggt ctcgatctcc tgacctcgtg atccgccggc ctcagcctcc caaagtgctg 43920
ggattaaagg tgtgagccac cgcgcccggc caataggtaa aatatttttt aaaagttttc 43980
tgtttaacaa agtcattccc tccagggaaa gattttcctt tgatcttctc cattttctct 44040
tgggttttca catgttttca ttgacttagg atttctcccc tgatttatta aactttgtgt 44100
tatagtaatt ttagttgttg tcttcaagtc ctacgcttgt ttgctttttt tgagacagtc 44160
tcactgtgtc gcccaggctg gagtgcagtg atgcgatctc agctcactgc aacttccacc 44220
ttctgggttc aagtgattct tgtgcctcag ccttccgagt agctgggatt acaggctccc 44280
gccaccacac ccggctaatt tttgtatttt tagtagagat gggtttcacc atgttggcca 44340
ggctggtctt gaactcctga gctcaagtga tctgcccgct tcagcctccc aaagtgctag 44400
gattacaggt gtgagccacc atgcccagtt ttatcatctt cccttagcag cctagagctg 44460
tggaacacta caagactgta gggtccattc gagttttatg cttttattta cttatttctc 44520
caagtcagtg tttttcatca tttttaaacc catgttctct tttgatgaag gattaatttt 44580
tattgcctca tttagttttt gaaatttcaa aatgcagcaa aaaggaatga aagcagtggg 44640
ctttattctc accctccctg accctcctgg agagtcattc ctacctgtat tccatttggt 44700
cttatttatt tataatatat gctacatgag agcaaggatt tttgtctgtt ttgttcatgg 44760
ctttacacca agttcccagc acacagtagg tgcacataac tctttgttga agagtggctt 44820
ggtcacctcc agttccagaa tgatttgggc cctgcccctc attgttcggc tctgcaggaa 44880
gcttcctggg accagatgct gggcctggct gcaagatcag gtcttccttc ctgcagggca 44940
cagtccatgt gcatcccagc agccacggca gggctgggga ggaactgatg tgggttgctt 45000
ctctgggcag ggcatggggg ttccctgcct gtggtggggg aagggggtac gtggctgtgg 45060
ggtggaaggg atgtttcttg ccagagggag tgggcgtggg aggtgcgctg ggtgagcagc 45120
ctctgaggca ggaagtgctt tccaggctgg ggtgggtttg ggcttttttg tcagagctgt 45180
gggaagccat taagatttta aagcagggtg gtaaagttgg gtttttgtta gaagagtctg 45240
tctgctgctg gaggcgagat ctgcagggaa gagttggcta ggtggatgag aaggggtgca 45300
gaggggcctt tcccccaaca tgaggatgtg gacagcctgg atgtgcttat ggaggtgaga 45360
gatggggcct gaggagagcc atgcactgca ggcgggcagg gtccatgctt ctgctgttgt 45420
tggtactttt atttgttttg ggtgactctg agaattaaat attaataaca gtgttgaagg 45480
aacatactgt atcattggcc atgatgcatg cctcctagaa agcagcgctg tacacagtga 45540
catgatcaca gcacccctgc aggactccag atgcacagtt tcttctcctc actgagagtg 45600
ttttggtatt gctggccttt ccagttctag aaatgtcccc tttgagactg acttcatggt 45660
ggctggtgtc agagtctgtg tcccttgtga aggaggcaga atcagagcta aattcaattt 45720
agcaaagatt ttctagacta agtaggaaga gggctcatca cccgaagtgg gcgtgggtgc 45780
tccccatagc caggctttgt ctacaggaca gcgggaggca gtcaaggcct gagccctggc 45840
caggtccctc ggagggcagg gagcctggag ctaggagaga gtggtgatgc agggtggcca 45900
tttccactcc cacagggccc tttgcccttc acacccagtg cccactgccc tgtctgagac 45960
gcctcatgct gtcctggcct gggcctccct ggccacctgc tggcatggcc tctcccattt 46020
gtgggggtgc cacttcctaa ctgcctctcc tctcacggct ctccttccgt gccccctacc 46080
ttgggcagga tgtgggtggg atatagtttg agtccatctc gggtgctggt tttatgaagc 46140
acacatttga ctccctcagt gggtggtgga gtgtgcagac ctgagctccc tgagctctct 46200
cgggtagccc tggtcacctc tcatgggcag ggctgcttgc acagctggag ggcaaggcct 46260
gagctgctgt tcccggagag ctagagctcg acaggcctgg actgcccagg aggcccgtgg 46320
aaaggctgat ccttcctcag ttgttgcagc tgagtgtgtg tggcctcctg atgctacatg 46380
ttcagttgcc ttttacttcc tttatgaggg aagttttatg ctacgcggta tttccaaagt 46440
gtgagctccc cagaggaatc agggactctg tctttgaatg tccagggtct gtgtatcctc 46500
taccagatag aagacccaag gcagcaggac tgggctcctt ctcttctttt gatctctgaa 46560
agtacgggac tctgcaaggt aacttcattc tttaaggcaa gccagagtgt gaatcctagc 46620
tcagcttctt ccaagcagat gactgggggc gagtcacagg acagctcgaa gcctccattt 46680
tctcatctga gaaatggggc tagtaacctg ccttgtgggg tggtttggtt gtaaggacta 46740
aatgagttaa tgaatgtagg catgatatat gtgtttgtgc ctattaacac tgtgattata 46800
ggcacttact gattattcag tgaatgaact gaaagcaata aaccaaattc atttattata 46860
tcatttggta tgtggaaaat tttcttctag tttggtgtac ttaacgtttc atactttctc 46920
tgtttactga ataataactt taattgaaca aaatcactac taattagtcc agatttcact 46980
gggcttcagt tagtctggct gtattattac tactccctgg gtcatggcaa ctgtagctga 47040
ggtgaacctt agagaggaaa gacaagtttt actggaatat gcctgaaata cagagccatt 47100
tagaagggtc atattctgcc cattgttaaa agcgctgtga actaaggctg ggcatggtgg 47160
ctaacacctg taatcccagt gctttgggaa gctgaggcgg tggttcaact gaggacagga 47220
attcaagacc agcctgacca acatgatgaa accccgtctc tactaaaaat ataaaaatta 47280
gacagacatg gtggcgggcg cctgtaatcc cagctactca ggaggctgag gcacaagaat 47340
cacttgaacc cgggaggcag aggttgcagt gagctgagat cgcatcattt cattccagcc 47400
tgggcgacag agtgagactc tgtctcaaaa aaaaaaaaaa aaaaaaaaaa aaaagcaagc 47460
actataaacc atcgaggggc ccctcgtttc ttacctaatg aagttcaggg tctggtcctc 47520
atgtgccctc ccagcctggc ctctccccag ccaagcccag tgcttcttag ggagctccct 47580
gtgtgtacgg gtcacctgct ggccctggtc tctgggggtc tgtttcccca aattctcccc 47640
accgaccctg tccgtttcct cctcagggaa gccttcctgt ttacatggtg ctcaggaaac 47700
tgccatatgc ttctgtggga ctgtggttct caaacttggc catgcccgag caccttttgg 47760
aactttcccc agaagtttgc aagtgggtgc tttttcaaag ctttccaaaa tcttagggta 47820
caaccacttt gggaccccct tcttgagggt actttgtgtc actcatgtga tgctacatta 47880
gcacaagctc cctagtaatg tgtacttggc cacaccttga gctcaaggcc atggagtgtc 47940
ttggcagctt agggtcccca gtgctctgcc ctttggggtg actatgtgta tgaatatgag 48000
ctggaagaag caggttctgt tgcttctttt tgttagcaca acagagagaa tgttgactca 48060
ccccttcctt ggcaagcccc gctgaagagg tgctcactat tgtggacccc tctgtgggcc 48120
aggctccccc ttttacaatt tcccagctca tgtccggccg gcagcttggg gacaaggtta 48180
gcccctgtgc tctgtgtgtg cgcttttagc gagtttgcca gctggaaaac ttgtttatcc 48240
cagagaatgg aggagtcatt tgacaagtaa ggcattaccc tggccaccta atttcaaatc 48300
agttggaaaa gatgcaagtt ttagaacttg ttattcctta tttgaactat cctgtatcac 48360
ggcaaactgt ctactgagtg cctgagggtg tacggggtag gtaagtgtgt tccctactct 48420
gggagacttc taacagtata taaagaagta gttctagtgc cctgtcataa gtagagtgga 48480
agaaggtaca aagtacagtt agagtggtgg tggttagcct tgggagggga ggtaagcttc 48540
tctgaggagc ggcatgagag ctggatgtgg ggacgggtcc cttttgcaga gaggactggg 48600
gaagagtcag ggagtcgggg acatccagga aataggtggt aggagtgtct gttcatgtga 48660
cacactagca gtgcctgctt tccaggtaca agtcctcctg tatggattca tttgttaact 48720
tagttcttaa agtgtttgaa tcttagtaat gattttaaag gaaatttaaa atagggagaa 48780
aatgggctgg gtgtgatggc tcacacccgt aatcccagca ctttgggagg ccgaggcagg 48840
cggatcacct gaggtcagga gttcaagacc agcctagcca acatggtgaa accctgtctc 48900
tactaaaaat acaaaaatta gctggatgtg gtggtgggcg cctgtaatcc cagctactca 48960
ggaggctgag gcagggagaa ttgcttcaac ccaggaggtg gaggttgcag tgagccaaga 49020
tcgcaccgtt gcactccagc ctgggcgaca gaacaagact ccatctcaaa aataaaaata 49080
aaagtaaaat agggagaaaa tgttcccaca gtagctctgc agttgttttc ttttttcatg 49140
tttctcttca gacttttttt tttttagatg gagtctcgct ctgttgccca ggccggagtg 49200
tagtggcgcg atttaggctc attgcaacct ctgcctcccg ggttcaagca attctcctgc 49260
ctcagcctcc tgagtagctg ggattatagg cgtgtgccac cacacccagc taattttttt 49320
gtatttttag tagagacggg gtttcaccat gctggccagg ccggtctcga actcctgacc 49380
tcgtgatccg cccaccttgg attcccaaag tgctgggatt acaggcgtga gccactgcgc 49440
ccttcctccc ttcagacttt ttaataggca cacattaaat tttacatgtg ttatatacat 49500
gtataatttt gtgttttgtg ttacaaagtt aaattttgtg ttttgtgtta caaaattaca 49560
ttttacatgt gttatataca tgtataattt tgtgtttaca tgtgttatat acatgtataa 49620
tttacatgtg ttatatacat gtataatttt gtattttggc tttatttgct gttttatcat 49680
aagattcccc atatcatgag tctctgtaat gatcgttttt tatggtggca gatatttcat 49740
tgtgtagatg tgtcatcact gatcagttaa actttatttg ctcactcttg cagcattagg 49800
aactgagaat gtttcagttt ttcctgttgg agataatgct agaatgtgca tttcagatca 49860
caggagggac atttagggag gtgagtttgt tctcccctgc agagcagctt ccatgctgag 49920
ccctgtttgc ccaggagagg gtgcagtttg cccttcagga gctgctttgg tttggtcttg 49980
ggttcctttt tgttacctgc cctgagagtt gagaagacaa aacttcctcc tgctttgggt 50040
gattctagtt tggttctggt ttacagcttt atttttgagt atttctgtat ttcagcttct 50100
atttacttta caccatttta gatagatcat catttgaact ttcagatatc ctaagcctcc 50160
agaatctcta gaggattggc atgtcacata actttaaaaa agcaatatca agaagaagtt 50220
gggtttgttg aagggaagtg gacagatcag gggactctgg cttatatggc taagctggtg 50280
gaggaagaca tgtgagcaga cattgggtga acgtctgctg ttccagtggc acatcctgga 50340
atgaggttgg gtggagggta ggtagagagc tgccccaggt atggaaggtg gtagaagaag 50400
agttgagtac acacttgcat gagggatggg gctggtttac aggaatggaa ccagcttgga 50460
aagaagacag aaggtgagaa gtgaatactt gttggtatca tgtaagaaca gagtgaagaa 50520
aaaggacagg ccggcccttg gtttattttt aaatttcagg aaaatggatt ggccaaataa 50580
tggggatcaa aaataaaggg tgtttttatt atgagccaag tgaaaattaa atttaagata 50640
tgtatgttgt tatggtttga ttgtgtcctc caaagttcat gtgttggaaa ctgaagcgcc 50700
agtgcaacag tattgagagg tagaaacttt aagaggtgat cagtgctggg tgcagtggct 50760
cacgcctgta atcccagcac tttgggaggc caaggcgggc agatcacctg aggtcgggag 50820
tttgagatca gcctgatcaa catggagaaa ccctgtctct actaaaaata caaaattagc 50880
tgggtgtgtt ggcacatgcc tgtaatccca gctactcagg aggctgaggc aggagaatca 50940
cttgaaccca ggaggcggag gttgcagtga gccgagattg tgccattgca ctccagcctg 51000
ggcaacaaga gtgaaactct gtctaaaaaa aaaaaaaaga aagaaaaaaa aagaggtgat 51060
caggccagga gggctctgct ctggggatgg attaatgctg ttattgtagg ggtcagttcc 51120
taataaaggg atgagttcat ctcctccccc ttgttctcac tgtcaccttt gacgcagcat 51180
gaagcccctc accagatgcc gcaccatgct cttagacttt cgaactatga ggcaaataaa 51240
cttctgttca tttaaaatta tctagtctgt ggtattctgt tacagcagcg caaaacagac 51300
taagacacat gtctagaggg ctgcttatgt gtaatagcta tataatactg catatataaa 51360
gggcagttta tatttaatgc tggtagaata tcatgaaggt agtgtatgtt agagttaggt 51420
ttagctactg tattagtttc tcatggcttc catagcaaat tatcagataa catgaaacag 51480
aagaaatgta attctatcac attcctggag gccagacatc tgaaatcatg gtgttggcag 51540
ggctggggtc ctaggagaga ctctgtgact tgcttttccc agctcctggt aattccaggc 51600
attccctggc ttgtggctgc atcgcttcaa gatctgcctc tgtctccaca tggccttttc 51660
ttccttcttc tgtgtcttct cctctgtttt cttaaacaga cacctgtcct tggatttagg 51720
gcccactcag ataatccagg atgatctcat ctcaagatcc ttaacttgat tacatctgca 51780
aagactgttt ttctaaataa ggtcacattc acaggttcca gagattagaa catggacata 51840
ccttttggag gccatcattc gatgccctat agctacaaat aagaatggtg tgaacaggca 51900
aggttttatt ctttcacacc aaagaaagta gtccttggtg agtatggtca ttctgcaagg 51960
tcgaccgagc ccttccagaa tgtgagtctt ctagtctaag aggctatgag gtgctagtca 52020
ccactgtgtc tcctgttgtt ggacggggag acgaggagag gagaaagtgt gttgcctggt 52080
aggagttcat aaccaggatt catggccccc tcaaagcggt ctgtggatat gactatattg 52140
tattaaaatt ggtttccact gtaatcataa gtattttatt tttggcactt agagaaattc 52200
tgagaaggag ttcataggcc tcaccagact gccagaaggg gtccatggca cagaacagac 52260
gaggagctct tgtatgactt ctccaaagtg tgacatggca cttctgcgga catcctcccg 52320
gttgatcttt agttatgtgc tcataccgta tagctctcag gatgcttgcc ctgaaataat 52380
catatcagaa taaccatgtt atgcagagag aagggtgatt tttcatgtct gtatttatga 52440
cttccttttc cccaagtaat atttttgaat agtttatggt atcaagaagt ttgatgaagt 52500
atatcataaa gaaggtcttc cttgttagct gtgtgaccta gggcagatac ttcatctttc 52560
tgagactcaa ttttctcatc tgtgaaatgg gataatactg gactgtatct caaaggtcat 52620
tggattggca cagaagtgcg ttctgaatgt ttcctagttt ctaatctcca ccaccagtca 52680
tctctactag taggaaagta atagggttta acttgctaac atgtaacagt tattctgatt 52740
tataggagtt tcaaaggatt tcaaacgagg ccaactttac agatatatta aaaatagctt 52800
ttgtagcaga agagtagata tccggaaaaa gttatcctta aaagttttca aggtataatc 52860
aatacaaaca ggaaaaataa aagttaaggg aaaaccaagt ataatttaac atataagatg 52920
cctttaattg gtagctaaat aaaaaggaag ctatgtaatg gatcagagta ttgcgtttaa 52980
atcttgtcat ggcagagcac ggtggctcat gcctgtaatc ccagcatttt gggagaccaa 53040
ggcaggagaa tcacttgagg ctaggagttt aagaccagcc tgggcagcat aacaagatcc 53100
tgtctctaca aaaaataaaa aaaattatcc aggtacggag gcatgcacct gtagtcccag 53160
ctacttggga ggctgaggcg ggaggatcac ttgagcccag gagttctagg ttgcagtgag 53220
ctgtgattgc accactgcac tccagcctgg gcaacagaga gagatcgtgt ctcaaaacat 53280
aaaataaatc ttgtccatgt ggcattcata tttgttgggt gaatgaaagt tccctagtag 53340
gcctacctag cgtgaaactg tggctgagtt tctcagctgt ttctaacaga catcagccca 53400
gaggatggtt aggactgctt cttgggtgag gaaccgtgat ctttatccag atttcatcat 53460
cagttttcct ttttagcatg tttggatttc agatattttc tgggcaaaat tcctaagcca 53520
gttaactttg gctcggagag aggaaaaact gttttttttt ttttttttca gatgagtctc 53580
actctgttgc ccaggctgga gtgccgtgct gcgctctcag ctcactgcaa cctccgcctc 53640
ccgggttcac gcagttctcc tgcctcagcc tcccaagtag ctgggactac aggcatgtac 53700
cactacacct ggcaaacttt gtatttttag tagagacagg gtttcaccat gttggccagg 53760
ctggtctcga actcctgacc tcaggtgatc cacccatctc ggcctcatgg gattacaggc 53820
gtgagccact gcgcccatcc agagaaactg tatataattg gcaaatgtct ctgcataaaa 53880
gactcttcct aattgctgca actgctggcc caggtctggg acagggagaa ttgtatttgt 53940
gggtcccaaa agtcctcttg agtgtgaagt gtctttgctc ttcctgttgg gaagccccac 54000
gttcgttagc agctcctgcc ccctgggctc acttctgcaa agcaagcctg cctctatttc 54060
tgctcaagtg cagtgttcca ggagaacctg actgcatgtc ccagctctgc cagctctcag 54120
tggtgggttc ttggccacct gtagcttcat tctcccatct gccaatgagg gtggtcctac 54180
ctagcacagc aatggtgggg cagtcgagca ccgggcagag taggtgctca gtgaatgaaa 54240
tactgtaatt attaacacat gccatggaca gcagtgcagg cctgcgggat caggtgcaga 54300
aggaagttaa cccagtgaat tccacacctg gtaatccaca ctgtgttctc aggttaaaga 54360
agcaggagga agcaggcatt gagtcaaatt ggtggctgtt tgctaagtgt ggggttttac 54420
tgaaggcagc acctgcttct gcagcacagc tggtctgaaa agccaggttg ctccttgtga 54480
gggcttaggg gtcggtttta acagtcactc caagcaggca cagggagaag atgctgtcct 54540
cttctggcag cctggctggt gagcagtgga accaattgtg gtgtctcttc tttagagttt 54600
ggggtgggag aagacgcagt tactcgtctg ggctgtttgt ttagattatc agtggggttt 54660
gcatttgtga aatctaagcc attttcacct tatgattgta tgtgtttgaa aaagtatttg 54720
tgttgttaac acttgttata cttgttaatt tttatgaaca agtgtagcgt acttgttaat 54780
tgtctttatt tacaaatggc agagaaaaca aagtggatag ttgagagact gtcattggat 54840
tatagtaatt tagtaaggga aagagttctt tgagaaaaga cctgggggga agatacatgg 54900
atttgattga attttttcct agggtgccta ggcagtgaat actttttagc catctttact 54960
cagtatgctt ttaaatgtgt cacggtgtga ttgagccaag ttccgtctgt ctggtttttt 55020
tttttccttg aaagttacaa aaatggtatc attctctagg aaatcatgtt aaaaaaaaat 55080
cccacgttcc cgtcccagaa taacctggtg tttcacagta catagtggta ggatcttttt 55140
atttccttga aacaacttgt tatcaaatta agataatttc ctgctctgtg gtagggagac 55200
tgctgtttat tgacccagtc cttcctcctc accacacaat tgaagaacct ggtttgaagt 55260
gtaaacctaa aaaacatgtg atccccccat accgtttttt tttttttttt tttttttttt 55320
tttaagacag gaggaggact gtgggagtgg ttatcagtag atctgtgcag aagggttggc 55380
cctgcagact gggtctggtg tagaatgtgc cctgtgggag ctgcctccag gcctgtggct 55440
gggtgtgtta atcagtgctg gacttcatac agaaaagtcg atgctgtttt cttttctttt 55500
tctttttttt aaatttggta gagatatgat ctcaccatgt tgtccaggct ggtcaacatg 55560
atccaatcct cctgccttgg cctcccaaag tgctgggatt acaggtgtga gccactgtgc 55620
ctggccaatg ctgttttctt tgtagctgaa ttgttcattg gctgcaaagc tatagagggt 55680
gggtcaagat aattagatgt ttggaaaata gttaagaggg ggattggctt ccaccccatt 55740
ctttgatttt ttttctcttt gaagaaagag ggggggctca agggacactg accttggagg 55800
caggagcctt ggggtttgtc ctgtgcccgt cattgaccgg gatcgcttcc ttttctgtaa 55860
atcaaggtca tgggcgcagc tgacttgcca aggctgttgc cagctctgcg ctgccttctg 55920
aggaacttga tggtttgctt cctgtgaaaa cttgatggtt tgctttaagg tatcactaga 55980
taccttgggg tgatatctaa tcacaccaat gaagagattg ggtatttgtt tttcccaaat 56040
ccctaagtgc tgatttctcc agggcagtac acaacctctt atctttagca ctcactttga 56100
cttgcataag tttcctggct tggatgataa gctatatggt caccctgctt attcagagaa 56160
aggttcatag tgttctttaa tgactattct aatacatgaa aaccattttt tgtgacttga 56220
gacataattg atgtacaata aactgcagta tttaaggtgt acagtttgat agtttttata 56280
cacacacact ttctctctct ctctctcata attacactga agctgtcacc atagtcagga 56340
taacatttcc atcaccctga gaatttcctt gtaatccttc cttctctgcc tcttcacagg 56400
caaacatgga tggatttgtt ttctgtcatt gtagattact ctgcatttta aaaagaatgc 56460
tatataaatt gagtaatgca gcatgtacta cttttttttt taatgtctgg cttctttcac 56520
tcagcataat ggttttgaga tttttcatgt tacgaatatc agtagtccat tgtatgcata 56580
ttccagcatt tgtctattct attggtgggc atttaggtag tttctagttt tgggttatta 56640
ctaataaaac tatgaacatt tgtatacaag tcttttgtgt ggacatattt tcatttctct 56700
tgggtaaaca ccttgaagtg gaatcgctgg atcatatagt aggtatatgt ttaacttctt 56760
aagaggctgc taaactgttt tctgaagtgg tgatccaatt ttatattccc accagcagtg 56820
tatagagagt tccagttgct ccacatcctc accaacactt ggtgtgatca gtctttttaa 56880
ttttatgtgt cctaatagtt atgtagtgtt accccattgt ggctttaatt tccatttccc 56940
tgatgactaa tgatgtcaac atcttttcat gtgtttgttg gtcatttgta tgtcttttgt 57000
gaaatgtgtg ctaggacatt tatccatttt tttaattggg ttcttattga gttgtaagac 57060
ttctttatgt attttggatg taagtccttt gtctgataca tgtgttgtga atgtttttct 57120
cagtctgtgg cttgtgtttt ctttaatgac acttttagaa cagaagtctt tctttttggt 57180
gaaattcaac ttatcagttt tttaaatggc tcattcttct agtattctat ccagaaaacc 57240
cttgtctacc tcggcttgca aagattttct tctataagtt ttgtagtttt aggttttaca 57300
gttgggatta ttattgatgt tcttcccccg acccccatat ggatattcag tttttgaggc 57360
agcgtttatt gaagatacat tccattcctc atttaattac ctttgctgcc ttttttcaaa 57420
agtcaattaa ccttttattt ttgagtctct ttccagattt tctattttgt tttattgaac 57480
tatattatgt ctgcctttac tgaaataatt ctacactttg ttgattactg tagttttata 57540
ggaagtgttg aaattagagt catctttgtt cttttctaac atagctttat tctaagtact 57600
tagcattttc atataaattt taatattagt ttgtcaattt ctataagtga ggcctgctag 57660
aattttgttt gagattgtgt taaatctgta gatcaatttg gggagaattg ctatcttaat 57720
aacattgaat ctttaatgat gttgagtttt ccagtacatt aacacgatct ctctctcttt 57780
atttaggtgc tttaaattta tctcagcagt gctttgtagt tttcagtgta gatgtcttta 57840
acgtcttttg ttagattcat ttcaatgtaa tttatgtttt tatttttatt aactaaatgg 57900
aatttataaa cattttatat ctgtttgctg ctaatatata agaatacagt ggattttgtg 57960
accttgcaaa atactgcttg tttaattcta gtagtcattg tgtagattcc ctagaaagtt 58020
ctatataaag ttgtatcatt tgcaaatagg gacagcttta cttcttcctt tctgactcac 58080
atgcctttta tttatttttc ttgcttcatt gcaaaggcta agattccagt acagtgttga 58140
ataggagtag cgaaggcagg aatccttcca ccttttccag tcttaacatg aaacagttcg 58200
gttttcatca ttaaatgtga tgttagctgt aggctttttg taggtatcct ttatcagttt 58260
gaggatgttc tttacttgat cgctgacagt tttaattatt aatgggtgtt gaattttgtc 58320
aaatgctttt ctgcatttat tgaagtgaac acatggtttt tttctccttt atattattaa 58380
aagggcaaat taaattggtt gattttcaaa tttaagacaa cttttcattc ttgggttaaa 58440
ccctatttgc tcataatatg ttttttattt attgttggat tcaatttgcc attattttgt 58500
taaggattgt tgcaccaata ttcatgaagg tattgatctg taatttattt ctctcccttt 58560
cttccctcat ttcttccttt ctgcctttgt caggttttgg tactttaaaa aatagagagt 58620
caggccagat gtggtggctc acgtccgtaa tccctgcatt ttgggaggcc gaagcaggtg 58680
gatcacttga ggctaggagt tcaagactgg cctggccaac atggtgaaac ctcatcccta 58740
ctaaaaatac atatatatgt agtgagtcag tgttaccccg cctctgtttt ctgataaagt 58800
ttgtgtaagc ttggtgttct ttctgaaata tttgctagag tttaccagtg aaatgatgta 58860
ggtatgcagt ttttttgggg taaagttttt gataataccc tgtgattttt tttttttaat 58920
gttcagattt tttgtttctt gtgtctgcag tgacattttc tgcattctct tccttttccc 58980
tctgatttat gtctgttgga tggagaagta gaaactttat gagagaaggg atatcatggg 59040
gcttgttgat ctgttttcat cccagcgccc ccgaaccatg cctggcacca aatagccaca 59100
ctgtaaatgc ctgtggggtt aattgatttg ttgttgctgt atctctattc cttggcacct 59160
ctgggaagca tttttgtctc cccccgtcca catgggaccg tgtcgtcact gtgctgtgac 59220
gggagctggc tgagtcaggc tggcaggctg tggctgccct gcatgccgtg ccctcccacg 59280
gtggctcttc aaattcttgg ctatgtgccc agcactggta cacagaccct ctgagtcagg 59340
gcttgccaat ggaaaaaata ttttcaacct tttttggtct tttaaaatat taaaacctat 59400
agttggaatt acttcttttc atttttacaa tgtacttgaa gtatcagagg aataaggaaa 59460
gccattgtaa gcttggttag tggaaaggga taaaccacct ctgagcatcc aaataaaatt 59520
aggaagcggg ggttctagat gagggaggac aattccagga ggctcttgac cttgtatatg 59580
attccctgac tgggaatgtg gtctgagatg ccctttcctg gacagattac aaatgacagc 59640
ccctggagca aacacatgaa tcagccaggg agttaaaaaa gaacagggta gtttggactg 59700
ggcctctctc tttcaggaca tgactgctgt ggctacagac tgcattcagg tccccagcat 59760
ctggaaggag tctgtgccca cttatccttt gcatcctaag gggactgggt ctttgtgcac 59820
cagcagcagc cgtagaggtt gggcttggga atcaggggct cccttatcaa agctgggaaa 59880
cttagaacaa cagctgtgcc gctcatggac ctgtagtctc tcctgttaag cagagtgctg 59940
agttcatgtg atagcaaaca cagctctgcc agaccacagg gtcaccaggc aggcactcca 60000
tccctccctc cagggggaga ccacggcatg ccttggatga ggtgacttgg ccaactgtct 60060
tgtggcccca gctcctgaca ttacaatgtg atgactgtga cacttggaag agaaatgtct 60120
caggtatcgt ggtcctgggt cctgtggtac aggaccttgt ctctgcggtc ctgtactttt 60180
gcttcacaat tagaagaatt gaaagcttca ggttgtttca ggtatgtttt ttcaagaagt 60240
gcaatagtag tgtgtttata gatgttttcc ttagagttag ttttggggga gagaagatga 60300
ctgcccttcc atcctgcagg tggattggct ggggaatgag gccatctctt ttcagagtga 60360
gcagtgaacc atttttgtct gtacactgac ctggggctga tttggcatcc tgaccttcca 60420
gtctgaggga gttggtaagg ggctggaagg gcccattctt tgtgtgtgtg ggtatttttt 60480
agagacgggg tcttgctgtg ttgcctgggc cggtctggag atcctgagtt caagcaatcc 60540
tcttgccttg gccttccgag tagctgagac tacaggtaca tgctggaccc acactttgga 60600
ctctgtccct gctggcctag ttctttgcca agagcaaaac ttgagagcac cctcacacag 60660
gtaacagtta gaccttgtca ggagacatgg ctgttttccc agacagctga gctttcagac 60720
taaagcacag aaaagttgga ggacatggga ctccttagcc cacaaaagaa actctatttt 60780
aattttccat gtgaaatagg agtagggtac gttagggtag ggcatcttgg ttatgagatg 60840
cctgcagcaa gtgccatcag ggtggctgcc agctgagtca tctccctcaa agagctttcc 60900
tggaaccact ctccccggtg atgtcagctc cttcacctcc attgctgtct ctagctgcag 60960
gggtggttgg agacccagta ttttagctag gccctgccag aggccattgg gatagcaggt 61020
caatggatga aggaggttgt ataggcaaat gggagtaatt atctctgatc ttgatttttg 61080
taggaaatag gcgtagatta aggcatagat aaatttgaaa aggcatagat acattaatta 61140
attaattaga gatgaggttt cactctgtcg ccctgtctga agtgcaatgg cgtgatcaag 61200
gttcattgca gctttgacct cctgggctca agtgattccc gcaccttagc ctactgagta 61260
gctgggacca caggcaggca ccaccattcc cagctaattt ataaattttt tttgtagaaa 61320
cagggtctca ctgtgttgcc caggctggtc ttgaacacct gggctcaagg gatcctcctg 61380
ctttggcctc ccaaagcact gattggcagg catgagctgc tgcgcccaac caggcataga 61440
taaatttaaa gacacctttt actgtagaca atttggaaaa tagagaaaac cagagggaaa 61500
agaaaaaaaa gaatctctca gtcctaccac ttgatgtgtg aacctccagt tttcccggct 61560
gcttgtgtcc tgcctttttt aaacacaata cgatgacatc agtatgtccc cctttccctc 61620
atttatgttt tattgtggta gaatactgtt ttattgtggt agaatacaca taacataaaa 61680
tttagcatct taaccatttt taagagtaca gtataaatat gcccttttat aaattacttg 61740
tttttccctc ctcgtgtggc tttgttttct gtgtggtagc cattctgtgg tttacttaac 61800
cactctaagt attgaacaca caaacaggct tgaatcaatt catttgaaaa ggtgtggaca 61860
agactttgtc ctaagggtga cacctggccc agccagcaga tgtgattgtt ctgccttggc 61920
caccttgctc tgggaaattg tattgcttag tcaggttgac cttcagtgac caaaaaagtg 61980
gatggtagtg tcaagggctt cgggtagctt atgaaactct ttttccttct catcttgtta 62040
ctttcctctt gatacttact tgttaactac agtgttacta tagacgcctt tgggtatatg 62100
cagatttacc attagttaat cccagagaaa aatggataaa ttatgacagc gtggtggctg 62160
tcagacttaa gaatgccaaa gcattcccgt ttctctccct ccaccccatc ccttccagac 62220
ttactaccag ggacctttgg tttgcctttc cttgtcacca ggactccgag gtctttcagc 62280
tccttgtttc ttctgttcag tagctgaagg atgcaggtac tctgccctcc tgctgtggtt 62340
tgtttctcta gcgagaagtc cagcagccca gctactgaaa gccaaggtca ctaacgcagg 62400
atgcagtcag cccaggagga gcacagccct ggacatgaag cttctggtct tacttctccc 62460
accttcctgc tacggtgtgc attgcagccg caagctctgc cttggaattg cttactgtgt 62520
cttagttcct gtgtgcattt ttttattttt tatttttttg agacagtctt gctctgtcat 62580
ccaggctgga gtgcagttgt gcgatcacag ctcattgcaa cctctgcctc ctgggttcaa 62640
ctgattctcc ctcctcagcc tcctgagtag ctgggactag aggcacccgc caccacgcct 62700
ggctaatttt tgtattttta gtagagatgg gatttcacca tgttggccag actggtcttg 62760
aactcctgat ctcaggtgat ttgcccacct cagcctccca gagggctggg attacagtca 62820
tgagcccctg cgcctagccc cccttgtgca ttttttaaaa ggtgcagttc tgtatttact 62880
gtagtgttta tgtggtaaaa tttgttcatt taaaaacatt taatattgct gttgttccct 62940
tgatgcttgg ttacaaattt gcataagttc tcagtggcct gccccagctt acctattccc 63000
atgggacttc tttttacttt tattgtgccc ttttgtagag tatgagggtt tttaggaact 63060
caaaaattgc attatggcaa aaatacctgg aaggttttcc tgatgctaag attcttttta 63120
attccccttt taatacaaat aacatgtatc attatagata attaagtgca gataacccaa 63180
acaaacaaaa accactcaaa agtcttatca ctgagattct agattaaaca ctattatata 63240
gacctgcgat tctcaaacat gggtagggat aaggcagtgg gggaggtgag attggcctga 63300
agaggacatt tggggactcc acactggttt gtcacagttg tgggtatgga gagcaggggt 63360
acgtgctgct gacacctagt tggtaaagtc cagggaagct gctcagtgtc cccagaggca 63420
caacagtgtt gtgcgacagc ctcacaacaa agaattattt ggctcaaaat gtcaatagtg 63480
ctgaggttga gaaaccctga tatggacaga tagttatggg gcctttttct gtgaatatta 63540
ttaaatacac tttagtttta caaaaatttg gattatttat acagactagt ttatgacctg 63600
cttttaaaac ttattacttc atgaacatct ttctgtgtcc atgactatgg gcctgtgaca 63660
taccattgtg tgagcatgtt ggagcttact tcaccagccc cctgtctgga gactgaggtg 63720
ctgccagcgt tttgctattg aaaccacatt tgtttgtatt ttgccttctg catgctggtt 63780
gactatggcc agcccatgtt ggggcaccag ctctacatct ggggtgcctt tcatgggtaa 63840
taatattccc ttcctgccag aggccccccc gccaaccatg gcagtcccca atctctagtt 63900
ttctcacagt tgaacataac tcaagcttaa tgaagtactg ttgaaatagt gaataggtaa 63960
gtaacacaat atttctgtca cgtttcattt ttaagtagaa ctttcacttt ttgcttcatt 64020
ttactttatg ggtttctaaa aaaataaata aattaaaaca acctatcttc tggtaggtta 64080
catgtgactt taacttcttg ccaagttggc tttgctccat acctgggctt cctgagttcc 64140
tggggaggca ggagtgggtc agatggagga tgccttgctc tgactgtgct gtgggtggca 64200
cctgtcagtt gtcatgctgg ggaccccctc cttcccccca aagctgctct gaggctgcag 64260
gtgagatgca gcccaggaga ggaagtgcat gacagctgtt tgggcccacg ttccctttta 64320
ggttgcagac agggcagcgt gcagagctgg tgggctgggc ggggtctgac acagtgctgt 64380
gcggagctca cccggacctg ggcactcagg ctctttctat atggggaact ccaagagctt 64440
gtttgtgtgg tggtgtctat ttttgtgttt tgtgtggtgc tctgtgagga agtctgttgt 64500
ctacgcacat cccagctgct ttgaatggtc tgtctctggg ggcttccagg tagggaattg 64560
tgtacgggga atccaggatt cgggcagcat cggaacagca ggatgtgagt aacaggaagt 64620
gacagaaatg acccagggcg ccagatgctt attctcggcc acctttccaa gcgctgcagc 64680
ccaggagcta tatttagcag agtgtttccg agtgcctcat cctgccccca gcaccgtccc 64740
tttgcccctc ttttggttgg tggctgattg cacggtactg atttgctgct ccagcgttcc 64800
tgctctactt cgtaatctgt aggctcttgc ccattgactt taacacccag tttttgtttg 64860
tgctgggtca cttcaatttt gatacacgtg gagcagctgg aaactgttct gagcaggaag 64920
ggcagcaggt aagagcccca ggggacagtg tgccatcata ctgggaggct gttgggtggt 64980
gagttcaagg tcagggtttg gaattaagcg gaaggaattg agcttccttg taagatgctc 65040
cagagggttg cttcttggct tgtatgtctt agaaatggaa ggctggaatt tttaaggtat 65100
aggctttgtg gtgtgacttt actcatgtgc tagaaacatt ctgtggttct cacctggcca 65160
gacagaaagc tgcaggtgga agaggcttgt gtgtggtgaa ttcctacagt ctgagctttg 65220
tcacgggaaa atttccctcc agtcccccaa agcaagcact acagagccca gatttgttct 65280
gctttgggtg tgggtggatt ttcaccttgt ctgtcgacgg tgcaggacct gtccctgtgt 65340
gctttgaggt ttctagggtg tgatgttggt ttgtggtttg tggaggggtg tgtgttggga 65400
gggaaggtgt ttttgctgtt ctcctctaaa agctcccttc tgagtggtcc cgccaggacc 65460
tccctttcct cccttcatga agcatccacc ttgttttcag acactcgagc tatttgggat 65520
tcaggaattg actctgggat gagaaatttg agagacaaat taggaacagt tgtgtctgcc 65580
atgagacgcg tggcagtcgg caggggcctg gtggggtgta taaaagccct gggaaccctg 65640
cataaagggg ttgggatggt aaaggagtga attccaggct caggcgctca ggagattccc 65700
ctcccccagt tccctcagca gagtctggct actggcatgg tttcaggctg acctgttaac 65760
cttccgtatg gctaaactac aaatataggg catggctata ttgtgtgtgt ctctagttct 65820
ggcttgggca tgttagcata tttttgtgcc aaaacattta aaacattcaa aaagtaacac 65880
atgaacccag ctatgactgc ttccagcctg agaaataaac ataatagata taacagaggc 65940
acttggaatt ctctttccta tcctcgtttc ttcctgctcc cccttccctg ggggcatcct 66000
aactttggtg tttgtcattt gttttcatgt ttatatactt ttttgataag tgtgtgtagg 66060
cataaacagt atatagcatt gttgaactgg ttctgaaatg tcgaataaat gttatcagac 66120
tggacagcca cagcattacg cttcctggat ttatccctgt ggctacatct agctttagtt 66180
aaatggttca aggtttaata caactgattc ctgattcctg gagttaaatc agaatttctg 66240
gggaacgagg catgaaccgc agagctcctg acaggcgcgg cctgagttga ggcccacgat 66300
gctggttttc gtggcctctg tagtgttcca gtacctaaga cgtcctgttg tggacgtaca 66360
ctttcccaga ttccctgtga tcagtagtgc tgctgtgaat atgcttatct tcgtcttctt 66420
ggcacatggg caagagtttc tctagaatgt gtttctaagg atagaattgc caggtgtgtg 66480
catcttcagc ttgactggtg atcgtcaaat tacctccaga actatcagca gcagtggtca 66540
cgtatgagtg atctcatttc tatagtgtct ttaagttttt cttttttaac ataccaaact 66600
gagggcaaga tgaagacctc atgagtgaga taagacattg gacattgctg agactttaat 66660
cgacaccgtg ccctcagcat gtccacacgg acctgctggc cctgccgcca ccccagctgt 66720
aaagcttgct tccacccaca gtgtcccctt cctgggatgg gagcagcacc cagccagctg 66780
ctcggaggtc actgtggact cctctctgtc tcaccctgtc ccgtctgctg tcctcagagc 66840
acatccagag cctgcccact ctcctcacca tcatctcgtg atggggttac tgaggagcct 66900
cccaaaaggt ttcctgcctt ctttcctgca tcttactgtc agctttcaat aaagcaacca 66960
gaatgatgct ttcaaaactt gagcttgcat ggcttcttat tttacgtgga gtaaaagcca 67020
aagttcttac acctgcatgg ccctctgtgg tcctgatgct tgcaggttgg cccctggccc 67080
ccttcctgat gccagcccca gccacgcacc acgcgcctgc ttctgctcag cccttcccac 67140
ctccttcctt gcttccttcc agtctctggc tccttcctcg cctcctcccc gtttttgctg 67200
tggagtcccc tggcccccag acctctcttt tctggtctcc cgtttttcca tagggcttgt 67260
caccagctac tactctccat gctgtgtaat tcacttcttt aataagtctt taatttactg 67320
cctgcattca aatgtaactt ccgcaggagc aggaatcttt tctgtttgct caagtgaaag 67380
actgcctgaa tttatttctg aggaagaaag aaagaatttg gagcccaatg atgaagatag 67440
cacaggagag aggaggtgaa gttgagggag cagtttctga cttgggaggt tggggggatg 67500
ggacaattac tggtctctgg gaggcagtgg cagaaggacc ttgaggcccc ctaagtgtgt 67560
agtaggaccc ccgaggggca tggccagtgg gctgtggggc tgcagaggca gcttcttttg 67620
gggccttgtc ttggcaccat ctcggccact cccagagcat acattggtat tgccgtagtg 67680
ggtgctgggc tggcccgccc cacccaggaa gtgcactact gtttgagggc aggagcctgc 67740
gattctgaca tcctctcttc atggctgagc tcctcaggtt acatagctcc actgattcct 67800
caagcactgt tgtgtttaga aatgaaacct tccatttcca gggccctgcc ttgtgcaggc 67860
tcaagtaccc aggccacgtg tcagagccca tagcaaaatg agcagctcaa ccggagggcg 67920
tggtccatga cactcctgcg tgtgcttgga ctcaggcgca gggacaggcg gggcagctgg 67980
catttctacc cacccctcct gacatagagg acctggtcct tttctttgag aatgtgtacc 68040
aaaggtgtgt cggctgtgtc cacataatat tttcttggcg tcagatgttt catgggttgc 68100
actaactaca aatacaggac tttagataag attacacttt taacttgcgc tgcccacata 68160
cgcccttgtc cttaagaaac acagcattgt tctggagtta ctccttggtt ttcccagttt 68220
aaacttaaat attgttgatg gtggttactt atttttaatt aaagctttta ttttgagatt 68280
ctttgtaccc tttacccagt tgcatgcagt ggtaacctct tgcacaactc cagtacaatg 68340
tcacacccag gatactaacc tcgttacagt ggagatgggt agcctccaag ccgcagagat 68400
tttccttgtg cccttttaca gcctcacaca tgtccctctg taacccctgg caaacactca 68460
tctggtctcc atttctataa tttggtcttt tcaagatgtg atataaatgg aatcttatag 68520
tatgtaacct ttggggttgg atttttcact cagcgtaatt ccctggagcc tcattgaggt 68580
tgatgagtct tatcagtggt tgttcctttt tattactgag tagtattcca cgggtgtacc 68640
acagtttgtt aatcatttac cccctgaagg gcatccgaat agtttccagc ttttggtgat 68700
catgaataaa gctgctgtaa acattcctgg gtaggtttcg gtgcaaacat gaatctccat 68760
ttctctggga taaatgctga agagtgtaat tgctgggtca tatgctagtc acatgcttgg 68820
ttttttaaga aactgccaaa ccgttttgca gagtggccgt aatgttttac atcccaccca 68880
acagtaagat ccactttctc catattctct ccagcaggtg gtgttggcac tagtttctgt 68940
tgtagccatc gtgataggtg cgtagggctc tctggttgtg gtttcagtgt gtttctctga 69000
tggctaagga tgttgagtat cttctgtgtg cttatttgcc gcttgcatat cctcttgtgc 69060
tgtcgggggt gaggactcat ttccaggtgg tataggagac atcccggctc tcagcttggc 69120
ctcctctgga tactctgtta ggtgagtgct ggagtgccta gctgcggcct gggagtgggg 69180
tgggcatggt tttttcttgt ggcgctggct ggagtaaggt gggtgttact gccgttgtca 69240
gtttctgtct tgtctgactg cccccttcct ggatccttgg cctggaagag caggcttttg 69300
ttggggcttt ccacccaccc ccccagtatc catcactgtt ttcggctgct gcttctttag 69360
ctccaagtct agggtatacc aggtaaaaag aaaacccaga gggccaccac agtgtcatcc 69420
ctttggacaa gacccttgtc aggctgccat cttctctcta cctttcaggg tctttttgtg 69480
ttgattttct gatgcccatg gttttcagtt ctcagtgaga ggagtgggga aaagtacctc 69540
cctgtcatct gaatttggac ccgtgaaaag tgaagagggg gtccattcag aatgttgtgc 69600
ctctacccat ccctgctcgc tcgtcatgac cgttggaccg ttgtggtccc cgggcctcac 69660
attaattact cttaggccct tttggtttgg cctgtggttt cagcgtgaca cagtttgctg 69720
gactttgatc ttttttgtca tttaaagtgt catttatgaa tgagatccac gtccagatcc 69780
ctgcatgtcc aaattcatgg ttagaaatgg ttggacagga catagccatt tgggtgctgt 69840
gattcagcct gatgtcaatc agtgaactgc ctttgtcatt atcctccaga tcttatttct 69900
ccaccttcta ttttgaactc ttgggaaacc tggtcagagt gggagggaca actagtcaga 69960
tgacttaatg agatgttggt atcgtccttg tgctgatcct ccaagccagt caccctgcca 70020
aaacggaaat gaaatgtgcc agacaccgct tgtactgagt gagcttggga gagctcgtgg 70080
tgagtgccag ttgcttccct gcctccggcc cactggccct ggtgtgaggc accacccaga 70140
tgaggagagg ctgcgggatg gaggtccagg gctccgcctg gagcccccct gcctggtgtc 70200
ctggccacat cagctcattt gctgtgggac tgtgagcagg cccctcagcc gggttcgtca 70260
ggttgtggag aagctgaatg gagcagataa cctggaaaac acgcggtgga ttgccgagac 70320
cttctttgtg cctcgcccat attagccaaa ctgtcccttg ttctatcagc tgccatgtgt 70380
gtgtaagcca gagtccaccc tcttttccat ttgagaaatc acgtctgcat gtctccagta 70440
tgtctccttt ttcaccatga tttctcagag atcactccct gcggtttaat aaccccctgg 70500
gctaattctt cccaggacat gggaggacat tttgtctggc ttggcaactc atttagagta 70560
gcaaggtatt ttctcatttc tcttggaaaa tcatgtactt gaatcaagaa tagaagccaa 70620
aattgttctt tcaaatagaa ttttaaagct ttttttttta atccttaaca tataaacgta 70680
agactttatt tttatttatt tatttatttt taagatggag tcacaccctg tcgcccaggc 70740
tggagtgcag tggcgtaatc ttggctcact gcaaattcca cctgccgggt tcacgccatt 70800
ctcctgcctc agcctcctga gtagctggga ccacaggcgc ccgccaccac gcctggctaa 70860
tttttttgta tttttaatag agacagggtt tcactgtgtt agccaggatg gtctcgatct 70920
cctgacctcg tgatttgccc gcctcagcct cccaaagtgc tgggattaca ggtgtgagcc 70980
actgtgcccg gccgacttta ttctttttta atagctcatt tttggattgg caacacatgc 71040
aagtggtaca gaaatcttaa ggctaaaaag atataaagtg tttcccagcc actcagaggt 71100
cctctcagtt agaggtgact aatattagtg ttttctctgt acccatactc ttcctgcaat 71160
tggcttttat ctattaacag tgtgtcttag aggttgttcc atataagaac atgtagagta 71220
gcttcagggg ttttagtggc tgcatagttt tctgttatat gaatgtactg tcattactgt 71280
agccagtctc taccagcctt atattgatca ctatttgttt ggtttcaaat attttgtctt 71340
tatagtgaat gccgccacaa ataaccttgt atatacagta tgtgatttct catgaagata 71400
caggagagga taaatttata gaagcatggt tgttgagaca caggtgtata ttttcaagtc 71460
tgacagattt taccaaatgg tttccataga ggttgtatta atttttgccc cagtgtatga 71520
gaatcagtag accatattat aaaacatttg atctctgtga atctggtagg ttaaaaaatg 71580
ggatctccta attttaactt gcatttgcct tataagacag cgttttttca taaacgttga 71640
aaatccattt ctaacactgt tttaacatag tgctgccaga ctctcatatt catgcttcat 71700
atttcatatt catattcatg tttccacctt tctctccctg tctcttgtac agttattttc 71760
taaccagatt ttatgcagga gtctgggcag ctctgcacac ttttcttttg agttatgtgg 71820
ttatgtgttt ttgagaaatc ccaagttctg tatccttttt gactgaggtg cagcattcac 71880
atggaggagt gtactcatta cagacgcaca gcttgatgca tgttcccgac cacggagaac 71940
actgcagccc ccggaatccc tcctgtgtgc ccctcctgtc aaagcagctg ctaggagaag 72000
ctagcatcta ataccataga ttagttatgt ctgttttttt aactttatgt aatgcataag 72060
gaaattacac agagtatatg tcgtcttgtg tcaggcttat ttctttcgct gttgtaagat 72120
tcattacatt attgcttgtc tcccaatgta tgagtatact acagtgtatt cactgtaggc 72180
ctgtttagag tagtgatgct atgaacattc tcgtatgctt tgatgaggaa ggtatgcgtt 72240
tgcatttctg tgggatgcgt gggtggaatt gctgagtcac agggtatata caagttcagc 72300
tgttttctga agtagttgca ccaaattgca ctgtcaccag cacttgatac tgtctgttac 72360
agctcagcca ttgtgagaga tgcatcaccc tgtagcttta atttgtactt ccctgatgac 72420
taatcaaatt gagcaccggg tcatgtgctt tattggccat ttgtgaaata gctattcaag 72480
tctttcgtcc attttactat tagtttgtct gctcttactg atttttaagt tctgttaccc 72540
tcaagagaat tccagcaggt gtgtaaaaat tcacatctgt ctatggctgt tctagcctgc 72600
ctcaggattc tgtgagaaat gcatccacca ttttatccac tcctcctctg tgacatcacg 72660
tttctttctc cagtcatcaa gcatcaagat ctgaggatat tttctctctc cagtgtgtag 72720
gtttccatgc agtcacctct gatgcagttc tgctccttct cttggtggga cgtcctgcag 72780
cctggccttt tgaatccctg ggatgtcatt catttgtcct gttgagttca gtttattgcc 72840
ctgctttttt tttttttttt tttttgagac agggtctcac tctgtcaccc aggctggagt 72900
gcagtggtgc aatcttggct cactgcaacc tccgcctccc aggttcaagt gatcctccca 72960
actcagcctc ccaagtagct gggattacag gtacatgcca ccacgtccag ctattttttg 73020
tatttttagt tagagatgga gttttaccat gttggccagg ctggtctcga actcctaacc 73080
tcaagtgatc tacctgcctc ggcctcccaa agtgctgaga ttataggcgt aagccactgc 73140
gcccagcctt attgccctgc ttctgatttg caattatctt ttaagttgat tcaggggtgt 73200
gaactgtttc ttatttaata catttgcttg aaaaatatga gccatctttt agtctccaaa 73260
gacttttctt tgtgaaggct ggattttgga gatagtttca gcttttttac accattcctt 73320
ggttgccagt agttatgata ctggctgcag tccagacata gggatgctct tagtattcct 73380
tagagcatct ccctgcaccc tgccacctgc cctggtgggc agggtgagca gccaggaagg 73440
catagcctga gggcctgtat ctagcccctg ctttctcgcc tgggtccttc ctacccatgc 73500
tgtctcccaa atcaagggat tgaataggaa gtgctgctca gaacatcccc cagaatcagc 73560
ctcccgaaga gactcaccct cccctaccag aggttgggct gtggctggtg ttaggggaac 73620
aggagtagga ggggagccag aggaggagga ggtgggccct tgcctaaggg gtgcctgctg 73680
gttggtgtgg gggctggagc tcgccaggag gggtgtgctg agaagatgga ggcatggcat 73740
ggaagtgtga gtcatggcaa atctcctgtg tgcagctggg gaccgacata gagaaggcag 73800
gcccagttgt gtcccctctg tgggcagcta agaaggatgg attctgactt atttggtggg 73860
actctcctgt gacatttctt gtggtttggg agagtggacc actgatacca gagcagtctt 73920
aagaaagatg ctcacatggg aaaggggtct cagcagtgtc aaatgatgac atcaaagctg 73980
agggcttcga ccccaaggta gcaccgatag tgacagtgcc cagaacatta tcaggttgca 74040
ccaactggca cctcacaaca acaaggctag gatgcgacac tgctcttaat agctccggtt 74100
ttcagatggg gcagtggagg cacagggcgg agaagcacct gctctaagtt acacagctag 74160
caagggcttc agactcaggg aatgtgccag gccctgtgca catttggtcc tgttcagtcc 74220
caccacagcc ctgcaggttg cttctagcat cacttttctt gacgagaagc aaagagggtc 74280
tgcccccatt tcgcaaattt atcagtggcc aggtaggatt cagatctggg tctctctcag 74340
gcttcttcac aacagaacag gcacaaataa gaggtttttt tttgttgttg ttgttgttgt 74400
tctgtttttt ccttagaagc caaaacccag gttctctgac atttatctgt tgctcagtgt 74460
ttattgtctg caaacaacag cacaggtgaa ggcaatgatg ccattggtca cttgtatctt 74520
aactcactgt ctttaaacct aatgcttttg tctataattt gctgtctagt agtgcccaat 74580
acccacaaag caattctagt acaccctctc cttcagtgtg tgggtcaggt gggcccaaag 74640
atccatcttc tcaaacgctg aggctgagtt ctggagcaaa gttggcactt cagctcgtaa 74700
aggctgccgt gggagtagta gactcaggac ctaaaacatc tccttgttgt cttctataaa 74760
tatcctgttg catgactcct aatataatcc ccgagttatg cacagtaagg tatattatct 74820
ttctcttact atatttacta tgctgacaaa agtgttcaaa tattaaaact cacccagggt 74880
gaacagttcg ggacgtgtgc tcagacttga taggtagaca gggacggtgc cgatgacatg 74940
cacccactcg gccttggcag ctcccagtct cccatgaccg tccctcagtg gctgtccaga 75000
gactccctga gtcccactct cagggcccac tttgtcgtct tcatggctga gtcagtgtgg 75060
gaaatagtta tctgcctgcc tctccacgct gtgagttctg tgaggggagg aactttgctc 75120
accatgttgt tagaatcccc agtctagagg agacacctag ccagcatctg ctgagccggg 75180
gggtgtcctc tggagggaga ggggctgttt gtggtgctct caagcttgaa cagcagcagg 75240
gcagaaggca gacggcccct ccgggcctgc ctttgccgtc tctccttcgc cctcactctc 75300
tcccagctct gctgcttccc acgcccagcc cggccccagg tgttcttctc ccaccaaccc 75360
aggatatgtg gaagaagaag cgaaccatgc agtggcgacc cagttccatt tatcccctct 75420
gcggtgaaac ttagtcactg gagaatctcc ctgtaaagca ctttctatgg tttctgagcc 75480
agaaacatgg tcatttaata atttaaattg ggtattccta aattgggtct tcttaatgta 75540
aattaaagct atgagatgtg ccgaaatcta aaagttaaat aacatatttt gtttttgaat 75600
ccatggggaa gcaagcattt tcctaacact gttggtgaga atgcaaaatg gtacaacccc 75660
tgtgggaata atttggcaat agctagcaaa attacatgtg catttactct ttgtcagggc 75720
aattctactt ctaggaattt accccagaga tacactggta aaaacaggaa aagatgcttg 75780
taaagataat tcacggcaac actatgagaa atcgcagaag aattttaaac agcacaaaat 75840
tcccatccat agggcgctgg ctgagtccta tacagtggag tactgtgcca ctgttgaaag 75900
aatgaggaag ccctggatat tgctaaggag tgatggccgg gatatgtaat taaatggaaa 75960
ggcaaaggtg gagaaaagtg tccatgctac tgttgacaaa agggacaatg tgatatacat 76020
gtttgcatgt atcttaaaaa tggaaggaga aaccttactt tctctctctc ttttttggta 76080
aagcagccta tgggaaccaa gataggggag agatataaaa gctagatttc taaatctacc 76140
ttgtttgtag atttgacttt ggaactccat cgctatatta taatcattat aaaacaaaat 76200
taagtaaaag gttatgaccc ttgaaaattt tgatatacac tatcaatttt ttctctaaaa 76260
agtttatacc ctgtttacct cctgtcagta cttgaggaga actctttttc ccccacatgt 76320
ttgtcagtac tggatagtca tcttttaaaa ctttgccaat cccatgggca aaaaatagat 76380
tgctattttc atttgcattc tctgatgact agagtgatta agcagctttt tacttgctta 76440
ttatccattt tgtatttctt ctgtgaggaa gtccaagcta gagcaatcaa acaacaacaa 76500
aaaaagaaat aaagggtatc caaattggaa aggaagaagt cagattatcc ttgtttgcag 76560
atgatgtgat cttatatttg gaaaagccta aagaccccac caaaaaaact attaaaactg 76620
ataaattcag tagagttgca ggatccaaaa tcaacatgca aaactcagta gcatttctgt 76680
atgtaccaac agtgcacaat ctgcaaaaga aatcaagaaa gtaatcccat ttacagtagt 76740
tgcaaataaa ataaaatacc taagaattaa ctgaagaagt gagagatttc tacaatgaat 76800
actacaaaac attgatgcaa gaaatggaag agaacacaca aaaaatggaa agatactcca 76860
cgttcatgga ctggaagaat caacattgtg aaaatgttcg tattacccaa agcagtctac 76920
agattcaatg caattcctat taaaatacca atgacattct tcacagaaat ggaaaaaata 76980
attctaaaat ttatatggat ccagaatagc caaaagaccc agaatagcca aaattctcct 77040
gatgaaaaat tggaggaatc acattttctg acttcacatt atactacaga gctatactaa 77100
cccaaacggc gtggtactgg cataaaaaca gacacagaac aatggaacag aatagagagc 77160
ccagaaataa attcatacat ccacagtgaa cacatttttg acaaacgtac caagaacata 77220
tactgaggaa aggacagtct cttcaataaa tggtgctggg aaaactggtt atccatatgc 77280
agaagaatga aactagactc ccatttattg ccatatgcaa atatcaaatc aaaatggatt 77340
aaagacttta agacctcaaa ctatgaaact gtgaaaacac tggggaaact ttctaggacg 77400
ttggactggg caaaggtttc ttgagtaatt cccacaagca caggcaacca aagcaaaaag 77460
tggacaaatg gttaaagctc ctgcattagc aatgcaggaa aaaagcagtg aaaaaaagct 77520
cctgttttta acaagttaaa aagttcctgc acagcaaagg aaacagtcaa caaagtgagg 77580
agacagccta cagaatggga gaaaatattt gcaaactgcc aggcgtggtg gctcatgcct 77640
gtaatcccag cactttggga ggccaaggtg ggcggatcac gaggtcagga gatcgtgacc 77700
atcctggcta acacggtgaa acctcgtctc tattaaaaat acaaaaaatt agccaggcgt 77760
ggttgctcac gcctgtaatc ccagcacttt gggaggccaa ggtgggcgga tcatgaggtc 77820
aggagattgt gaccctcctg gctaacatgg tgaaacctcg tctctactaa aaatacaaaa 77880
aattagccgg gcgtggttgc tcacgcctgt aatcccagca ctttggaagg ccaaggtggg 77940
cagatcatga ggtcaggaga tcgtgaccat cctggctaac acagtgaaac ctcgtctcta 78000
ctaaaaatac aaaaaattag ctgggtgtgg tggcgggcgc ctgtagtccc agctactcgg 78060
gaggctgagg caggagaatg gcatgaaccc aagaggcgga gtttgcagtg agcggagatt 78120
gcgccactgc acaccagcct gggggacaga gtgaggctcc gtctcaaaaa aacaaaacaa 78180
aacaaaacaa aaattgaaaa ctattcctct gacaagggat tataaccaga ataaatcgag 78240
agctcaaata attcaaaagg ggaaaaatct aatcatccag ttaaaaaata ggaaaagtag 78300
acatttctca aaagaagaca tacatatggc aagtaggtat atgaaaaagt gctcaatatc 78360
attgatcatc agagaaatgc aaataaaaat tacaatgaga taatgtctta ccccagttac 78420
aatgactttt atccaaaaga caggcaataa caaatgctgg cgaggatgtg gagaaaaggg 78480
aaccgtacac tgctggtagg attgtaaatt agcacagcca ccatggagaa cagtttggag 78540
gttcctcaaa aaagtcaaaa tacaattacc gtgtgatcca gcaatcccac tgctaggtat 78600
ataccaaaga gaaaggaaat cagtgtatcg aagagatgtc tgcactcatg tgattatagc 78660
agcactattc acaatagcca agatttggaa gcaacctaag tgttcatcaa cagacacatg 78720
gataaagaaa atgtacatat acacatggag tactatttag ccatgaaaaa gaatgagatc 78780
ctgtcatttg ccacaacatg gatggaacag gaggaccctt aatgttaagt gaagtaagcc 78840
aagcacagaa agacaaactt cacatgttct tatttgtggg agctaataaa aaaaaaaaga 78900
aaacagttga actaatggag ataggcagta gattgatggt taccagaggc tgggaagggt 78960
agtggggctg gggggatggt taataggtac aaaaatgtag ttagaataaa cgagatctag 79020
tatttgatag cacaacgggg tgacaacagt taataatttg ctgtacattt aaaaataact 79080
cagagtatac ttggattgtt tataacacag agaaaggata aatccttgag gcaatggata 79140
ccccatttac tctgtgatta ttctgtgcct gtattagagt gtctcatatg ccccataaat 79200
acatatacct accatgtacc cacaaaaaaa attaaaaaga acgttgatgt atttcttttg 79260
tgaaatgcaa gttcatagcc ttttttatat caggaagatt ttttttctac tgattgataa 79320
gaacccttta tatattatgg atatcatttt catttgttga ttattaccag gtcacagctt 79380
tatttccagt caagttgttc aggtcctgca tagtctgata ttgaggtttt ctacaagaac 79440
atttatatgt gatacatgct catggtattc cagacttaca gctgagcaga cttccctcaa 79500
ctgttcaaat gctggccatc actgtgggct ccctgaagca gtagcaactg tgtcttccac 79560
tgttcggaaa acaacagttg ttacttcttt ttttatttcc ttagggttta ctactgtgtc 79620
taagtagcaa gcaattataa atgtccactt aaattgattg ctgatgaata tataaaaact 79680
aaatttcact gtctttttgg tttgagatca ttcttatttt taatttttag tgatccttga 79740
taaccatttt tgttttcggt tcagtgtgaa tacctgaatg aaatagtaat ttttatgtct 79800
gtgtgaggtc ggttttaaga aagcgttcat agctatcagc acttgccttt tgttcatgga 79860
tctgttgaac ctgtttcttt ctctaggtca taactccatg caggaagctc atcttgtgtg 79920
ctgataacag aaaagaaatg gaagattgga ttgcagcatt aaagactgtg cagaacaggg 79980
agcactttga ggttaaaaaa gaaaataccc ttctccaaat gcctcctgtt gcctccctca 80040
ccccagtgtc tgctgtctga gtgtctccca cgtgcggacc cacagtctgg agctcacgtt 80100
cttagcatgt tctttataca attaaagctt attgcttgtc ctctcagcag acctgtcctt 80160
tataaacctt cctcctctcc tctcttggat actttgttta atcttgtcca agttactgca 80220
tttaacaatt taaaagagaa gtcttatctt tgccctcttg gtttcgttct tccagcccac 80280
ccagtacagc atggaccact tctcagggat gcacaattgg tacgcctgtt cccacgcgag 80340
gccgacctac tgcaatgtgt gccgtgaggc tctgtctggg gtcacgtcgc acgggctgtc 80400
ctgcgagggt acggatgtgc gtttgttatt ctgtcaggaa aggtggcctg gcattttact 80460
tgataaagcc ttggaaatcc aaacccagtc accataaata agccgttgtc acccatgtgg 80520
tcagtcaagg gcacagcgat ttctgtgatg ccattcttgt ttattttacc tgccgaagag 80580
tccttgataa atcatttttt atagtgctca gagtgaaaag ggaagtggtg ggtggcaaaa 80640
ggagaaatgg gaaatctaga gcacacagag ggaaaggcac tgaaggaaca gtggtcggcc 80700
cctgtgtctc acactctgca gccggggaaa cggggctgtg catatatgga ctgaaagtgt 80760
gttacagact tagaggtcag ggctgcaggg tttgggcaag ggcattcagt ctggtggcaa 80820
agcagtgggc tagagcaggg cttgttagct atagcctgga ccacaccctg cctctgcctg 80880
tttttgtaca gctcccacgc ttcagactgg cttttaaatt tttaaatgat tggaaaaaat 80940
caaaagaaga atcatatttt gtgacacatg aaaattacat gaaattcaaa tttgtgcccg 81000
taaaaaaaca ttgtctctgg ctgcttttgt gctacatgac agagttgatt agtggtgacg 81060
gaagctggtt gcgacctgca gagtctccac tgctcactct ctggcctgtt acagaaagct 81120
tactgatccc cagctttccc tgccgctgcc ggtcccaccg ccatcagcct ctaagcgtat 81180
cacagtagtt cacttataaa atgggagtgc cattggttcc ttccttgact tttctggagc 81240
tggacggttc tcacaacact gctcagcatg ggaagctctt ggcacagaca cagcttgtag 81300
gctcatgtgc cccttctctc acagtgtgca aatttaaggc ccacaagcgc tgtgctgtgc 81360
gtgcaaccaa taactgcaag tggaccacac tggcctcgat cgggaaggac atcattgaag 81420
atgcagatgg ggtatgttaa gaaataccac ctgtggggcc ctgagccagg gtcccccacc 81480
tgcacggccc catgcaagcc tcctccctgc cctccctgcc actgtttcat ttgagatggt 81540
cacactggca ttgggtggca cagtggaaat tatatgcggt ctccgtgtgg ttgtcgcacc 81600
cccgagctcc atcctgtccc tgtgagtctt gtttgcacct ccgacaggtg ctatgggtag 81660
atggtacttc acaggccctg ccatcccttc cctcactggc catcagggaa ggagcttgtt 81720
ctgggaagaa tgccttggct gagttcacaa cgagcatttc ctggctgccc tggacgtgga 81780
accttgggag cgtccctagt gcgtgcctct gtttggttgc agattgcaat gccccaccag 81840
tggttggaag gaaacctacc tgtgagcgcc aagtgcactg tgtgcgacaa gacctgtggc 81900
agtgtgctgc gcctgcagga ctggcgctgc ctctggtgca aggccatggt gagtgtgggc 81960
cctgcgcccg ggctggaggg gagggcttgc tccctaccgt gcccatgcgg gccttgcggc 82020
tccgcatgat ctgctggatc ctggtaaatt aatcccagag gcccctccgg ctgagagtgg 82080
gtttttgaac tgttgggtca ttctccttct tagctatgtt ttggggtatt tcttcctttt 82140
gcatttattc ctgtctttag acatatgcag atgtgtattg ttatgacaga tgtcaccctg 82200
catcatgcgg cactgtagcc gggttgtgag gggtcacctg ggacaattga gctggccgcc 82260
tctgtggtgt ggaagcagga aagctgtaga ggccatttgg agcggcgttg gctctgggca 82320
gtgttgacag tgagcacagc catgtggaag gggtgcagcc cagtggcctc ctgccaggtc 82380
ctgggtctca tcgttgctct gggtggtgag atgtgcttcc agggagagac tcagggagcc 82440
tccatgtact tgcttctggg ttggtcattg tgaagtggct gctgcagtca cttgcctagc 82500
acatctggct gccaggagga agccaagaca caggggacac atagaggcac atggccccag 82560
gagccctcac cctcgtcctg aaagtttgag gtagctgtgg tcgaagggcc agaaggttgg 82620
gtacaggact gtagctcaca cggtgtgaag catgactggc tcctgccggg tatttccgtg 82680
ttatgccttc tcaagtgcaa agccagggcc cagggccccc gatgatagca ggccggccca 82740
gggcccctga tggtagcagg ccagcccagc tctgaaatca cctgcctccc ccgaggccag 82800
ctcatcagct acagggcagg aggatttctg gtgtgtgtga aggatgccag tgacccttgg 82860
tgacgcgggg actcttgttt caggttcaca catcgtgtaa agaatccttg ctgaccaagt 82920
gcccacttgg cctgtgcaaa gtgtcagtca tcccacccac ggctctcaac agcatcgact 82980
ccgatggtgg gtaccacaca tgcttatcct tctcatgcac gcccacacgc ttccttctcc 83040
acgcactttc tcttctccag ctctggagtt ggttatcttg gtgagatgtc agcaagaggt 83100
caggcacagc tgttgggggt gctggaggag ttgcacagag cggcacacgg cgccctgatg 83160
ctgcggcatt gcccttagat gggccagaga cccaagcctg gcacttgacg tggaggtgat 83220
gctgttgagt ggcacccagg cttagacagg cctgagaccc gagcctggca cttgacgtgg 83280
aggtgatgct gttgagtgca acccaggtct ggggccttct ccgtcatgag ccattgaagc 83340
tgtgccccat ctctgcctag cacatgctgg cacactggct tgcagctgct ctcatgtctg 83400
gctgggacat ggtggcacct gttgacaagt actggtggaa agggggatgt ggggtacatg 83460
gctcagagga gatcaagaag agaagacagc agaaaggtgg catttggaca gcttgtgaat 83520
gtggaggtca gatggatggg gctcccggcc tcacacatgg agaccggctg tggggaactg 83580
ttcactgacc tcctcctgac ttacaggtgt gcatgtgtca ggtgtgtgtc ctttgggggg 83640
gtctgctgct gctgattcca tcagtggtgc cctcagcgtc ttccgtggcc tatatatttt 83700
cttctgttcg ttcttgcgtc cagggttctg gaaggccagc tgtcctcctt cttgcacaag 83760
cccactgttg gtcttcgtca attcaaaaag tggggacaac cagggtgtga agttcctcag 83820
aagattcaaa cagctactaa accccgccca ggtcttcgac ctcatgaacg gaggcccaca 83880
cctcgggtag gaagcttgta aaatatatct ttcttggagt tttaaaaatt gtgtagatag 83940
tgtgtgcttg ttaaaaaaaa aaagttcaaa gacacaaagc tttaaatagg aaagaaaagt 84000
tgaactgctt ccttcccaaa ttgcacttgc agaggtgccc actcttaata gaggtgcatg 84060
gccttccaac tttgaacaca gtgcgcgtgt gcacacacgt acatacatcc atgtacacac 84120
acccatgcac gtgcatcttt tgagccaatc aggattcttc tttacctgcc gttgcacaaa 84180
tgccttctgt atgtgtctgc atacaacgtt gtgggtgtat tttctttcat tttataattt 84240
tttatttatc tgtctatcta tcatctatct atctatctat ctatctatct atctatctat 84300
ctatctatct atctatctat ctgtgggtgt attttcctgg cgtgcctcgt tctttgtaac 84360
agctgcctaa cattgaggaa gaagctgtcc tgcagcgagg ccaggaggag tgtttgctga 84420
gaggcacagg aggccgctcg gtgtgcaggt gctgcaaggc aggaacacgt aagggcggcg 84480
ttgggccaga gcgatttcca ctgtgcatca gcagcacaga gattagactg ttcctctgct 84540
tgctggagag ccatgtgtgt tctttgtagt tttttacttt tcataagttt gtagaaaaca 84600
tttgcctttg tgaattttgc catttgaatg aatttcttcc tctggaagca tcagttccag 84660
gtcggagctc taagaggact tgctggcact gccggagatg tccaggatac ccgtagtggg 84720
aagtgcctgc agagcctgtg gtctggcctg tatttctctg ggaggagtca gtggggtctg 84780
tgtattagga gccaggggct actctgatgt gaacctcggc cagctccctg cgtgtccttg 84840
gcgtacatgc cagggtaaga ggaacatgct gctcgtcgtt ggtcctgtgg gtgtcttctg 84900
tgttgctcat ccccactcac agccaggcgc agtcggagag cagtcacaga tggcagcatt 84960
ccagcctgct tccgcaaagg cagtactccc acattttctg tagaaagact tcttatctga 85020
atggtggagg attgcattca ctagtaggct gatcaagata ttttaatttt aattttactg 85080
ttttttgaga caagagtctt gctaggttac ccaggctgag tacactggtg caatcctggc 85140
tcacagcagc ctcaacctcc tgggctcaaa ccaccctcct gccttagcct cctgagtagc 85200
tgggactaca ggtgtgtacc actatgccca gctaattttt tttttttatg ttttgttgag 85260
cctcacaaaa cttttaaaat gttttgtaga gtggtctcac tgtgttgtcc aggttggttt 85320
caaactcctg gagccaaatg atcctcttgc ctcagcctct caagagtgtt ggattacact 85380
gcctggcaaa gaaataattt tagttaaaaa gtggggaaag tggagatata atacgtctgt 85440
tatcacaatg caccaagcag gctgaggttg ttattaaaca tggtaccagg ggtgttggag 85500
gaatgctgtg aaatggctgt gggcagggca ggttacacag ctgaactcga gaataacgaa 85560
atattcattt tggtgtgcaa gcaaaacccc atgtttcgta gtgggagtta agtatgagat 85620
gggatgattt aggaagcccc cacagcggcg taaggggagt tgagtcgtca tttaccattt 85680
ctggaagcag ctcatctcac acagctcaca gcagaatctg gagctactgc ttcatgttcc 85740
agttcctggc cttgacctgt cacctcttct cccgagagca gggggcctta caggtgtcag 85800
tgttctgtgt ggagcctggg cttggtgccg catcacctat gcctgtctgt cttctgagca 85860
ctcattctgg gtcagacact gagctcgagg cagggtgcgc aggtgagcca ggcggggagt 85920
gcagatgcag ggaatgggta ggagcacacg cagggtcccc cggcacttca gtgggggtga 85980
cacagcttct ctgggaaccc ggtgggggca gggtcgcaag tcaaactggg cgtccttcca 86040
cgtctccccg agctggcatc cgaggagctc tagtgttctg aaggctgcag ggaggcggga 86100
ggcttctggg ctgagggcac cgcttgtgca gaggcgaggc aagagggaat gcagtggggc 86160
caggccaggc agcagcagaa aggtggcacc tgccgtcagg gagggctgcg ggtgctggcc 86220
aagaggttcg actccttcct gcaaatgagg ggcagcctca taaagcaagg cccgtggcca 86280
ggctcgtgtt ttagaaaggt cttcctggaa ctcatgggga gctttcagga agggtgtcaa 86340
ggtgactgag gctcctgtgg gactctgcga gagcacggtg gtgacctgag cgggtggctg 86400
ggttgggtgt ggaggagagg ctgccaggag gggctgggtc ggctgcaggc tgagaggagg 86460
tgggtctggc ctctggactg ggttggtggt cgagctacca ttctccgagt agggatgtgt 86520
cctgttggat gtgccctggg ataccagagt ggtgtgttct ggaggacagg tgcaagtgtt 86580
ggctttcagg agtggcctgg gggctgttga tccagagtca cctgtgtggt ccttgaaact 86640
ggatgtggtc acacaggaag aggatgagga gtgagcagaa gcggcactgg tctcctgagt 86700
ggggacgctg ctgggcaggg gcagggggag cccaggaagg aaggaaaccg aggagttagg 86760
agggtaggag gcgtgggtca catcaccgga ggactgagtg ggcccaggca tatgtgctgc 86820
agtggggaca cgcagcccgc agcaggtcag gcagcctggg gctccagggt gaccagaaca 86880
agggccaggg cggaagccag actgtggccc agggccgggg agtgccaaga ctgagggtgc 86940
agggtgatgc aggcagccca gagggcatgc tgggaaggct ggcaggggcc acatgtggat 87000
ggggcaggga cagtgacgca gggtgggctc acatggttag gggccacggc aggctgtgcc 87060
cgtgagcctg gcaggggatg cagttttggc ccaccacttt gcctgtgatg tctgcagagc 87120
gtgcagtggc tcaccaagct gagtggtctt gtcgctgggt ggggcgtggc tggtgggagc 87180
agttggctgg accccagtgc tgctgtcgtc cctttgacaa agtggaccct gagtggaggc 87240
ggctggtgtc acgtggcagg gcctgtgcgt gctctgcctc tggtgcaggt cagccatgag 87300
gagcacaggt ggcccctcag ccccgtactg acaagcctgt catttgtcct gtggaatgga 87360
tgtcatttca cggcctttct cttttctctg cagcttacgg ttattccaga agtttgacac 87420
attccggatt ctggtttgtg gcggggatgg aagtgttggc tgggtcctct ccgaaatcga 87480
cagcctcaac cttcataaac aggtaccagg acaggaggga gcccagccag gagcagagag 87540
ggtgcggagg ttagagggaa atcatgcagt ctcagctcct gttcatctcg gagcacctgt 87600
tctcaggcca gaaaccattg gtggttttgg ggagtgtgca gtttggtggc cagggcagag 87660
aggggagagc ctgggccacc ccctggcatt gtggaggccc gggggctctg gccatgatgt 87720
atgaggggga cctgaaggga gctacgaaaa gaattgccca caaaggaccc acatggggag 87780
cagggctggg tggggctgtt gctttactgg gtaatttttg tcttgaggcc tcttgcttgt 87840
gagaagggga cggcagtata cttgagtttc tcaagtcaga gtcatggttc attggactta 87900
gttttttgta ttaaaataaa aatagatttt cctgattgtg tataaaaatg ttcatatagt 87960
catttaattt ccacaccaag ccacggcctc cccaggtgat cagccagtgc caacattttg 88020
ctgtctctga cctctcttga tcacagtaca tacaatgcac agtgcacttg taatttaaac 88080
gggctattct gttactgctt ttgttgttgt tgtttttgtt tttgtttttt tgaggtggag 88140
tcttgctctg ttgctgggct ggagtgcagt ggtgcgatct cggctcacta caacctctgc 88200
ctccccggtt caagtgattc tcctgcctca gcctcctaaa tagctgggat tacaggcgca 88260
cgctaccacg cccagctaat ttttgtattt ttagtagaga cagggtttct ccatgttggc 88320
caggatggtc tcgatctctt gacctcatga tccgcccacc ttggcctccc aaagtgctgg 88380
gattacaggc atgagccacc gcgcccggcc tgttactgct tttaaaaaac cactaattaa 88440
gatgttgcag acaccttgtg cctgtgtctg taagtaggca tctgtgtgtc gttttccact 88500
ggacacaccc gggagcccag ggccagctca cctccatgtg tgagcacgga gatcacttcc 88560
cagtggtctc ctctctgagc gcacccaagc ttaagtattg aaatgtgctg acaaactgcc 88620
tttcctcagg gctgtgccag cttccatgcc tgatgccttt aaagctgtct ttccccgtgc 88680
accatccaag ctgttcatct ctttagtttt tgtccagcta agtagaccaa aaaatgtctg 88740
acctttactt ctttaattcc tggtgaagtt gaacgcctcc tcagttggtt atgaagtttt 88800
aaataaatca cctgttcata tttttttttg cctcattttc tctttgagta ttcacctttt 88860
tttcctttaa aaatgggtgt gtgaggatta ttgttacatt aacttcttat ctgtcactgc 88920
agatattttt ttcccggttt gtcgtttgtc agttcaacat cctttttggg gggtggtctt 88980
ttctttcatg atttttgtca acgtctgtca tatttgcagc tgcctacacc ccaagattaa 89040
gatttgcatc tgtattttct tatgtttatt atggccccat ttttaaaaaa ttcagtcttc 89100
tgtgtgacgt ggatgtattt ttcagtgatt ctgtggtgcc tacccagctc tgctcacttg 89160
gtagtatttc caggtgggtg gatttgacag ctcgggccgt gaggccagtg gctcaggagg 89220
agaagtggtg ccgcctgctg gtggattagc atagactact ctaatttttg attttgtgta 89280
ttacttgcaa gttcactgtc actagttagg aagacagtgg aaccttgtgg ctgattttca 89340
tacgttcagc caaggtcagc acacatttct ctcccctgcg tctctttgac acctgatgtg 89400
gtggccatgc cttcgctggg cccctgccgc ctcggggttt cttgtcttcc tggctgctac 89460
tgctccatgg tggcctctcc ctccttaccc ttcccttaac gctgtgtcct cagagccttg 89520
ctggggcctc tcctccttcg cttttgaacg ctcagcgact tgcagggctt ctgctgtcgt 89580
ctctctcctg ggggcgcctc aattgatagc tgagccttgg gcctctctgg atgtctccta 89640
gtgcctcgag tttccaacac tacaccacgt tcagccccca ccctgcgttc ctttccttcg 89700
agtctgaaaa catcatccat ctagatgtct gagccaggaa atcggacagt tgttcttggt 89760
tcgtccgtct cttcctcctg cctgtttctc actaattgtg tcctcagtcc tgccacccac 89820
agtaccctgg cctctgtcca tctgcagctc acccaggcga cctttcccgg ggcatttctg 89880
cctgtgcacc ccccaagcac gatgcttctg ggaaaagtcc agacctttaa gagtcccagc 89940
tttgcctcct gcttgcttct ctgcctgtct gcctcctgtt tcctcgctgt cctcctcttc 90000
actgagctct gccttgcccc ctcccagtgg tgtctccctg cctggagcac catccatgcc 90060
tgctgtgcgc tgctctcctt ttcctttaag gctccaggaa gccctcgcgg agtcctcaga 90120
ccctctgggc acccttcagc actgggttct ctccatctag tgtgtcggct ccggtgtcct 90180
ggcctgctcg ctcctgcctc ccctactgcc aaatgtcccc ttggtgaggc aggaccttcc 90240
ctggtgtttg ctgtccccac aggcggcagg gcctcaagca tggtcacctc cacctggtgg 90300
gcagagggct gtacggtgct gtaggctgga ccacggcagg tttcctgcct caaggacagt 90360
aacgcctccc cacacactcc accgcagcct tcatggccct ggtcactctg ttgtcagagt 90420
caaaggctgg tgagctctgg gcagtgggca ttttaagagg cctcctaagc aatggaatgg 90480
tgtagtggga tctcattgga gctctgaaat gggaatccag gtggagggtg aggcctgagt 90540
aatgcatgag gtctcttcct ggaacagcag gcaggcgggc agaggctgag ctctggcaag 90600
gctccagggt agcctccaga ctgaggatgg tcctggcacc ttttttggat aggatttaga 90660
ggagagaagt gatactagtg atgtttttgg aagaagaatt tggcattagt gagtgagatg 90720
ctgtagtgga tggagggacg ggtggcgagg catcagagtg attccttggg gctgtggtca 90780
cggtggtgaa aatgggaagc agagggattt gggagacaga tcagagaggg tgtgaggggc 90840
tgaccatcaa gatgtgatga cagctgagag atggacctgt ggctcatcca tttctcccag 90900
aagcagcatc ttatctcaag ggcagtcatg tttctgtctc attgccaagg aaaatgccat 90960
ctgtcccctc cagtgggctc tgcctgtaat gtgtaagctg cgtggtttta ggtcacgtcc 91020
ccacattgct aacgtaaccc tcacggtggg ggacaaggag ggctgcgggc tgggaagtgg 91080
cccctgcccc caggtgtttg cctgcgcatc gtcccccatg tttccttagt gtcagctggg 91140
agtgctgccg ctcggcacag ggaacgactt ggcccgagta ctgggctggg gctcagcctg 91200
cgatgacgac acccagctcc cccagatctt ggagaagttg gagagagcca gcaccaagat 91260
gctggacagg tgagtgggga tgtgctccgg tgccgtatga ggagactttg agagacaggt 91320
ccctttgacc aggtgttctt aacctggggt ctgtggaaaa catgggccct ctgaaattat 91380
ttgtaaagat ttgacctgag tatatattcg gatagtcttt gatatttggt cagattatga 91440
caaggataaa aacaaaacag gttaagaacc agccatgccc taggatgatc cagtcttccc 91500
agaaggccaa gcctgagtgt gtcagggccg tggagaaggc agctgtgcca tctttggctg 91560
cttcagcccg agatctaata cccatcggaa gaatgctcct tgtcgtttac ttgaacagtt 91620
tcattttctc atattctgtt cccagaagaa gttttgggaa attatcctct agtgcctaaa 91680
gccactgtga caccttccct gagtaaggta ctgttgtccc gagtgacaca cttggcactc 91740
actgaccaca tgcctgtggc acatggggtg ctgatgagat gcctcctagc cttcctagtt 91800
gctcccagaa gcctggagtt ctgagcacag ttgtggtttt gcaatgcccc caccatttca 91860
ggcctcctct gtgtgccttg gggcctgtga aatgctcatc tcactgggcc agctggctga 91920
gccatttgca gctctcttga ggagggtaaa tccatttctc ccagaagcag catcttatct 91980
caaggtagcc atttatggga gaccttcctc tctttatgga gctgtactgc cgttagttgt 92040
ggagtgcaga catttgttct cagccaagtt atgggacaga gtcaagacca agggcctaaa 92100
aatgaagtca gaaacggtgt aaagatcaag gctgccagcc gtgaaagcgg acggcgcagg 92160
gttcaccctt gtgggcctgc acgtcttgcc gcctgtgcag ctgaccttgt gtgtgcaggt 92220
ggagcgtcat ggcatacgag gccaagctcc cccggcaggc ctcctcctct accgtcaccg 92280
aagacttcag cgaggattcc gaggtattgc tggcctgttc ttcacaccct gctcgcatgc 92340
tgatgtgatc agaactgtcc tgtcagcggt ttgcatcacc tcccttgcag agacgcctcc 92400
cctttggtgt tggggtgtca cagtcaggcc tgcggaggcg cagggtgaac ccatggctga 92460
gaggattctc actccccttg gcaggggcct tttgggcttt gtgaccctct aggggcttcc 92520
tggggttgtc ataggccctg ccgggtggtg gggtggtcct cctaatggcc tttccaccct 92580
gtccgtgcat ctcctcagct gcgcagtgag ccccaaacgg tgcgcgcccg ttccctcccc 92640
cgccgcggtg cccacgtgcc tggaatgctc tagccggctc tgccgcggct ctcccctagc 92700
cccccggctc ctgccccgtc ccacctctct gtggcgtctg cagctgccct tcgctcaggc 92760
tcctctagtc cagctggtgg ttcttttcat ttggtgattg ttactgttgt gtttaacgct 92820
cctacagttt ccctcagaga acagactttg tctttagttt ctattttgtg ctggtgcagt 92880
gctgggtggg gtagtacaaa gaggtgagct tttgtcaggg gctagggcaa cggtcagcaa 92940
acaaggcctg caggccagat gtgcctgggc ccacggcctt gcaagcgaag actggtttgt 93000
acatttttta tttttccttt ttttaaaaaa aaattttttt tttgagagga agagtgtgtg 93060
ggggaagccc agaatattcg ctgtctggcc agtagtgaag tttgcgaccc tggggctggg 93120
tcctaaggac agcagggatc ccacagggat agggctgccc ttctgacagc cagaacagat 93180
ggtgggggca ggagtgtgtg tccagatggg gctcacagcc aggtggaaac agcctctgct 93240
gcaaacggac ccaaacctgg agccgacccg ccagcatgcc gctgtcagga tgagtagggg 93300
tcaggacgga agctcctagc acaggccgtg ctgggatcgc agactgaagg agattcattt 93360
gcagtttgcc tgcagcttga cgaagctttt aaaatctctc acctagcact aggtgagtcc 93420
cagattagcg ttagaagtga gttgaggctt ggctgggtca gacagtgtct gttaggagag 93480
actcatcttt cccagcttgt gctggcaagg aagtggctga cagagtcact gggactgtca 93540
tggagcttgc tgtcacagag accaacagtc ctggccattt ggggtgattg caggtacagc 93600
agattctctt ctatgaagac tcggttgcag cccacctttc taaaatcctc acctcggacc 93660
agcactcggt ggtcatctcc tcggccaagt gagtgcctgg tggccctggg gagggcatgg 93720
tgccctggcc cccagcctgg agctgcctct ctagaagggt ctttctgttt ttctccccac 93780
agagtgctct gtgagacggt gaaggacttc gtggcacggg tggggaaggc ctatgagaag 93840
acgaccgaga gctcggagga gtcagaggtc atggccaaga aggtctgttc ccgtgccctg 93900
ggtgggaggg gcattgaggc agcgagaagc ttgctctgtc accagcagag ggccgtgact 93960
gcaggttgtc caggttcttg gtgatttgaa caaagaatta gacaaaacgc acagtaaagg 94020
aagacaagaa tgaagcaaca aagaacgaag gcagggattt attgaaaatg aaagtacact 94080
ccacactgtg ggagctgccc gagcagcggc tcaagggtcc agacacagaa tcttcttggg 94140
tccaaatacc ccctagaagt atcccattgg ccacttcatg ctcacctcat gtaaatgaag 94200
tggtagcttg cattcagtct gattggtggc agaaagcagc caaccagagg ctgaagtggt 94260
tacaaaggtc acactcctgt gcaaacatct gattggttgc aaaaagcaac caatcagagg 94320
ctaaggtgaa gttacaaagt tgcatttcta tgcagactaa gactcagctc gcaatcagta 94380
tggttggttg tggacagcca atttccccaa tttcccacct gccagggcgg gaaaggtggg 94440
gatttgcaaa gggagtagcc tctggtcttt ttgttactta ggcgtggaga gttaggattt 94500
tccttttgat cgagttctag gaagtctggg tgaaatggcc tgaggttccc tgcctgcaga 94560
ccctgttctc ctgcctcagc tctgcatgcc atttcctttc cttgttcagt gctctgtcct 94620
gaaagagaag ctggattccc ttctcaagac cttggacgat gagtcccagg cctcgtcctc 94680
tctgcccaac ccgcccccca ccattgccga ggaggctgaa gatggagatg ggtcgggcag 94740
catctgcggt tccaccggag accgcttggt ggcatcagct tgcccggccc ggccgcagat 94800
attccggcct cgagaacagc tcatgctgag agccaacagc ctgaagaaag caattcgtca 94860
gatcatagaa cacacagaaa aaggtaactg gccttgtgat gaggaggggc tttcctcagg 94920
ccagcactgg gcatgcccag cgtcccctga acacggagat gacagaaggg tgcatgttga 94980
gaaaacctcc actgcggccc tctccaccca tgtccaggca ccagaccccc aacgagttcg 95040
cttgccctcc ttccacccct cctctcacac cctcagaccc cttcatgctg cctcccctcg 95100
acctctttcc tggccctcat tgacttcact ataagcgtct cactcccgtg agagccttga 95160
ggtcacggcc tcacacccgc acacctgcgt gtccatgcag ccgctcctcc cgcttgcagc 95220
cctccagcct gcgccaggct cctctgcatc ccttgccttc ccctgcaagg gttccagacc 95280
tcccagcctg ttagcaggga cgccctgccc cagtgccagg accaggggga agatgggtgg 95340
gggtggggtt tcggagtcca agcctttagc cagaggttgt ttgaggaaga tcaggccgtg 95400
gggtgaggat gaggggccct ccacccagcc tgacagcgcc cttggctttg cacccgcgtg 95460
ctcagccgca cacactctcc ttgcacagct gtcgatgagc agaatgccca gacccaggag 95520
caggagggct tcgtcctggg cctctctgag tcagaggaga agatggacca cagagtgtgc 95580
ccaccactgt cccacagcga gagcttcggg gtccccaagg ggaggagcca gcgcaaaggt 95640
acttgtgcct ccacctccct ctgcgcaccg tcgtgtgctt ggttttggtg agacgtagcg 95700
ggcttgccag gggaggtttt agggcacttt ctcatagttg ctttggccac ttggttacat 95760
aaaaattgag cgcccaaggc ctgtttctgt gcatctcctg tgcgcgccct tgaggtgggt 95820
gtgtgcggtc tgtcttggtg gacagcagta gaacccgcga gaccccctcc atcagggcga 95880
ggactgcctc cctgaggagc acttgcgtcc tgccctcact gcttccttgg aaccacactg 95940
ggccccagaa ctgctcagaa ggggctgtgt ctggcagagg gaaggcgggt gggtgagcgt 96000
gggccttctt tgtccttgcc cctcctggaa cagcccacag cgcaggccct ggtggagggc 96060
acccccagcc tgtgcaggct gctgggaggc ccatgctcag aactgaccca tggccactgc 96120
atggccacca ctgagagctc tgctgtgtgt gtgctccgcc tcccacagcc cggactgact 96180
gggctcaccc ctccctccag cgctgccacc tgtggcctgt gttaacctct ccatgagccc 96240
agccccccaa acatgtgcac ccactcggtc ctccgccccc ttctttgtcc cacacacttc 96300
acgcaactgc ctgtggtttg cagccctccc tcctcagccc tcccacctgc tcgtgtcgct 96360
aaggaccccc caggatttca cagtctctat tccacacagc tgtaaggttt tctgctgtgt 96420
tgttacagtg tcgaaatctc cgtgtgaaaa gctgatcagc aaagggagtc tgtccctagg 96480
cagttctgct tcccttccgc cccagccggg aagccgggac ggcctgcctg cgctcaacac 96540
caagatcctg tacccaagtg agtggcggcc agcaggaggg actggtgggg gccctagcac 96600
aacactggtc ccgtcaaact gaaagagatg ggctcgctgc cctcggagag tttacaggcc 96660
cctgagaaag ataggtggaa ttgaaaaatt tacacgactg tatgaaaagt gctttttttt 96720
tttttttaaa aacaaaaaac aaaaaacaaa agccagatag tacccaaata accacccaag 96780
gagcccagga ggcgccattg aggaggtgat gctcgagtcg gggttggaag aattaaggaa 96840
ttatctgagt ggaaaaggga ggtggccggc ctgatgaggg aacccgaggg accatcccgt 96900
gcttctagcg tggtcgcagg aggcgcaggg agggtgaggt cctggccgcc tggagcattc 96960
cttgatattc attccttagg aaggcagcct tataaagcct taagcctcaa ctctcagaga 97020
tcattttggt ggagtggctt acatttaatg agaacatgaa aactgactct ataagccttt 97080
tttttttttt ttaaaagagg gtctctctct attgcccagg ctggagtgca gtgatgtggt 97140
catggcacac tgcagcttga cctcctggac tcaagtgatc ctccccactc agcctcccaa 97200
atatctggga ccacaggcac acaccttaga agccattttt ttgtgtgttt tgtaggtgtt 97260
ggtttctgcc acccagtatg gtttctttgt tccagtgatt tttgacctaa gactattggc 97320
aaaatttgga catggttata cataatttta gaaacattta attataataa cgttctgcag 97380
aataccggtc caccagcttc agagacacga gcttctccta aggctgtagc tcctgaccag 97440
caccacctct ttcttgtatc tcctttacag atgtccgggc tggaatgtct ggttccttac 97500
ccggtggctc agtcatcagt cgcctgttaa ttaatgctga tcccttcaac tctgaaccag 97560
aaaccctgtg agtatgaggg ataaaccgag tgggcatatt gttacatggc tgctagtgca 97620
tagaaaacag atctcaggat taactagaga aattagtgag cagttgccca gctggtggta 97680
gctgataagg aaggctgaga agtcgtggag attccactta aggagtggag ctggaaacca 97740
ctactgcaca tctgctgcag aggcaaagcg cacgcctccc atctccttcc caaggtccca 97800
cggtgcttgc ttgacgtccc ctgagcctgc atgcccttct gaggcttttc acaggctcag 97860
ctactcctgc caggagctgc ccttgtgctg ctcttcgtgg tcactctccc atgatcttgg 97920
ctggacctca ctgacttctg cttacagcct gccatcttcc tcttgccatc ccttccctct 97980
gctttcctct aacacctgct ctccttgttg gtgatgcaga accacagact ctgagctgga 98040
gggtcctctg tgtgtctccc ttgtgtctcc gagcacctta gggagacact agcctgtgct 98100
gaggcttata agggctgctg cgtgcctgcg tgctgatact gctactcctt gggggacaag 98160
gccttcttcc tctgctggcc tgtaaggcag tgaggacatg tatatagcag tttaatgcag 98220
tcttcctagg tattggagtc cattttggag acaagtggtg ttttgaaaac ctgtttttct 98280
gcactcatct ttatgctggc tgattgcagg ttctgggcag ctggtggcag ttggttaaat 98340
gtggccagcc atttttctgg agtggtgacg gacagtgaca ggaagaaatg tgcggttcac 98400
agaggctctg ggtttgggaa agtggacccc tagattccag gtgctggcct ggtacagcac 98460
ttcagtgtcc ctgttcctgg cctggtctac tcctcccctg gggctgcgtg gggctccagt 98520
tctcagccct cctgaggctt ttttccttgg ggaggccaga gctgtagtcc tatagtgagc 98580
actgtcccta gaggcccctg aactggatat ctcctttgtc tccttcatct gagactggaa 98640
cttccacttc tgttgctcag ctgggtggtc tcatctcttc ttttcacctg gggagacaaa 98700
gctgtgcttt gctgccttcc tgctgtggtg tgtgcctggg ccgtattgtg tgggccccat 98760
tgtagctggg cctgagcagc ccctggtacc ctgtcctctc ccactgcccc agccactgcc 98820
gcccctcctg ctccaggccc ctgagcccag tctctgctgc cttccctcat ctctttgtcc 98880
tgtttctctc cgttggatct ctctcttttc ccaggaccta tacatgctgg ccaggcactt 98940
ggtcttcccc ctggtaaaca gttttgtccc agagctttgc tctggctcag ctgtcgggca 99000
cttgaattag atggatcata aatacactga cacatgctgg ttgttctcag atctggcggc 99060
actggctcag taagctaaag tgtgtcagaa ttctggcccg agcaatgttc ccaagcccat 99120
ccacccattg agtttctttg ggaacttcca gaacatcctc ttctcctggc tgcagcctct 99180
gggtggagga acaggggttc ctcccttcat ccacttgccc tcggggggaa accccagtgt 99240
gaccctgggg ttggggaggg tgaaggccag gctgggcttt cccagcagct gggggagctg 99300
caggagcagg acttccagct gggtggggag aagaaacttg aatgagtctc ttctcgtctg 99360
tcgcacacgg ggaaaaggaa gccttgtgct gtggggctgg gatggatgtt ttcaagtcat 99420
tttccttttt aatttggcaa cagctttgct tgtaactagg gatgtttgag aaatgttttg 99480
agatccagag ttgaaatgtg tgagtttctg tgccataaac atatcttcag gtttggtgct 99540
gctggtggag tgtaagatgg gcagctgctg tggggaatag tccagcagct ctgccggagg 99600
ttcagcccag agctgctgtg tgaccagcag gcgcagaact gccgggccat gtgggattga 99660
actgaaaaca tgtccacgct agaagctgta tgcaaatgtt cctaaatgat aaccaaaacg 99720
tggaacatcc cagtgtccgt ctgctgatga gcaggtcaat agatgcaggt tagccacgca 99780
gtggagtatt atttggtaat aaaaatgaag cgctaacaca tgttataaca tggatgaact 99840
ttgaaaacat cgtcctgagg aagagaaagg agccagacac agagcccacg accgcatgat 99900
cccattcctg tgaactgcct agaagaggcg cctccgtgga ggtggaaagt agacgagagg 99960
cgccagggat ggtgaggatg gagagttagt tgctgatggc aggagtacag gctttctctt 100020
tagggggatg aaatgctcta aaatcgatta tctagtgatg gttaaatgac tctgaatata 100080
ctaaaaataa ttgaattgta cattttaaat tggtaaatta tctagtgtat atcttaataa 100140
atctcttagc agacaaaaaa gaaaaagtta ccagttttcc ccaaggaaga gaaatgctga 100200
gaggttggga gtctgaaata agactgctca gcagggctgt tgtaattgat ttaaaactca 100260
cctttgcaga gagtattaca cggagaaatg tgtcatgaac aactattttg gcattggcct 100320
ggatgcgaag atatccctgg actttaacaa caagcgcgat gagcacccag agaagtgcag 100380
gtaggtaaca ggctcaggag cacgtctgtc ttttgcgtct ttgtggcttc tccttccaga 100440
cagtagcaga tttctggagt cagcaggtta aagaacgtgc agaatgctaa ggcggggggc 100500
agaaatggag cccagatcgc cttgtcagaa gcacgggtgc tttcagagat ggaagggaag 100560
cacctctcgg gctggccagg tcaagggaaa ttcaacatcg gaaaaccagt gatggtggtc 100620
attggaatgg cggcatctct taatgagagc cccaagtccg tgatactaca gaaaagcggc 100680
aggtgtgcca agaagctatt gcacctattg cgtaagtgcc cagcattgtt tgtgggaggg 100740
tctgtgtgtt catcaccacc ctagctggcc ctcccccatc acacccgagc ctgcccacaa 100800
ggcccttgag tccaacctct gcaggaagac gggagcgtgg gagccccaag gggcatcact 100860
gggggtttca gtttttttcc tctaaaatta ctggatactc agtcctggcc tgaagagagg 100920
atggagaaaa atgagaaggg tccctcttct caagcttttc ttcctgggct gatgtagaat 100980
tctctcttgt ctgtgaaaca caagaagtga gggagaaatg tctccctccc caccccacag 101040
taataatcag agaggccatt cagctttgac atgattagaa ctacagagag ggagaaatga 101100
gtgtgggggt tgacggtgtt tgtgcagaga acagcccttg acccagaagc tgggagaccc 101160
ttgctggagt cttcgtccgc tgagtcagga tgggcttgaa tgaaccaagc cacgtggccc 101220
cctgtggcct cgccctcctc atggcgtcac tgccaccttg cggggagcca tgctgacacc 101280
tgagggtcca gctttagtca ttgctcaggt tacatgtagt tgaaaatttc taggaaaaca 101340
aaagcatcag aactgaaaga acttttgact ctgaggctct tccatgcagg agaaaatggc 101400
tcaggggccc cagggacata tccctgtaca gcacaggatg gtaacgtcag atcatttaaa 101460
aatccctgtt agtccaaaaa tcactgggaa aagtattaaa atacacatac tttagcaggg 101520
taaaataagt agttgaggaa caggggcatg cataatacat ttctagagct ttggaaccct 101580
ggtcaaacct ctcttgagtt tgtattgaga gctttgaaaa gttctcctga gaaaaattcc 101640
acttgtacaa atgtcattgg aaatttctgc agaagtcatt ggaaatgttg gttgacgtag 101700
gtacgaaggg actcctagcg tgtcatttcc agagctcagg catggggcgg aggagtgtaa 101760
tcaaggggat tggttcgata agctgtggta gagcagtgcc cggctgagga tggccacatc 101820
tgcagagagc gtgtggccac agaaggaagc attgccggcg cagggtaaag tggaccaagt 101880
aggtcgtgaa actgtaaaca agttactgca actggaaatt aatatgcaaa gaagactgag 101940
gaaatacata gcagcacttg gcatttgtca ttagcacgtg tggagggtgc ctacaggtgc 102000
tggattatgc atggaggatt atgaggagtg tcttctcctt ggtgcttttc tatattttcc 102060
agtttttcta tggtaagcat aattttttag ccagaaaaaa tcaggatgtg tagaagtttt 102120
tttatagggt tctataatgt tttaacttta tgtatttacc tttcagggta tgattacttt 102180
cttggcaaaa tgttactatt gagcaaaatt tcctattggt aaacgtatct ttttatgcat 102240
atctgcaaaa acaaaaatgt gtccttcaga tgttactgct gtaaataatt gctaaatgta 102300
gctgatttgt gggtcagatg ctgttcccag ctttcacaga aatgactctg gttaactata 102360
cgaagaaagc ccagacctat ggcaagtctt tgcttctgtt tctaggagcc gaaccaagaa 102420
catgatgtgg tatggagttc ttggaaccaa agagttgctg cacagaacct acaagaacct 102480
ggagcaaaag gtcttgctgg aggtgagtgg gagggtcctt gtcacctgca ggctggcctc 102540
catccatcag cagactgcca ggcctattgc ttctcctgtt gaccatttcc tccatgcaca 102600
gggacttgcc tggggatgcc ctggccacgg ctgtgctcct gagcccctgg cggtgggaag 102660
ctggtagaga aggaggggct gactcatacc tttctctttt cttttgttct gtgtctctgc 102720
tgctcagtgt gacgggcgac ccatcccact ccccagtctt cagggaattg ctgtccttaa 102780
cattcccagc tatgccggag gaaccaactt ctgggggggt accaaggaag atgatgtatg 102840
tatggggtgt gagcgggtgg gcctgagctc agtggggaag agctgtctga gagcaggggg 102900
gtgttctgct gtggctgggg tggatccagc tcttctgttg tgccagcagt ggggttgccg 102960
tggagaacaa gatagacagg gtcccccacc cagctcatcg tctagagggc tgagcagagc 103020
agttgtgtca gtgaaggtgg tcagtgaggg tctgtggtca gcagatgtgg tcagcgggtg 103080
tgacgtggaa ggagggtcag ggaaggtgtc tgggaggcca agacctgaag gatgagttgg 103140
agttggctaa gttaggtggg cagaggagag ggggaggctg ttccaggcag agagaattgc 103200
acagatgaag gctcagagtc aagacagggc aggcacatgg aggatgggag agaggtgccc 103260
cgactgcagt gggcagcagg ggcgtggaga gacaggagag ggctgcaggg cctgggtcac 103320
actgggctgt gtgagctggg gaagaagttt ggaatttgtg ttaagaactg tgggaaggtg 103380
ttgataggtt taaacctggt ttaaaccttc ctttgtacgt aatagcgaat agaagtattc 103440
agcgcttcct gcacacgtgg tgtgtgctgg ccccagtcct ggcactctgc agcgttaact 103500
cacttggccc tactgatggc cctggaggag cgtgccgtta gtttccccat tttacgcatg 103560
aggaaatggg ggagagagag attcagtaac tttgccgaga tgagagctgg gatttggtcc 103620
caggcagctg gtttcagggc ctgcaacatg aagcccgtca ggagtgcagt tacctggtaa 103680
cttctcgcca gctaggaggg gctgaccccc agagggaggg agtgagggta ggggcggcct 103740
gtgctcgggg atgtgtggag tggtggtcag ctctaacgtg tcccttgcag actttcgcag 103800
ctccatcatt cgatgacaag attctggagg tggtcgccgt gttcggcagc atgcagatgg 103860
ccgtctctcg agtcatcagg ctacagcatc atcggatcgc ccaggtagtg gccatggtcc 103920
tggggtgtct ggccgagtcc ccagcccgga gtgtgctaaa ttctggggca gtgcatggag 103980
cctgggaggg tgggcgcttt ccagggccat gtggctgcct catgtcctgt cctggacagc 104040
tcgtggcccc acttcctggg ccagagccct ttccttgtgc tatgcttgac agttaaattc 104100
tcaagataac tctttttaat tttttttttt ttttttgaga cagagtcttg ctctgttgcc 104160
caggctggag tgcagtggtg caatctcggc ttgctgcaac ctccacctcc ctggttcaag 104220
tgattctccc gcctcagcct tccgagtagc tgggactaca agtgcccacc accattccca 104280
gctaattttt gtacttcacc atgttggcca ggctggtctc gaactcctga cctcaaatga 104340
tccacccacc ttggcctccc aaagtgttgg gattacaggt gtgagccact gcacccggcc 104400
aagataactc tttcaaaatg tgtatcctgc ttgaaccaca gccttgcctg tcccctctga 104460
ggtgggatga gatagagcag acccaggctg gactctgccc gtgtctgcag ctgtcaaagc 104520
cgcagtgggg acggagccca tggctctgat gtggggtgtg ggaggatttc cagctggggc 104580
cctcgatcat ggttctgagg ccgagtggtg aagggctggg ggtgccccca tggcttattt 104640
ctgacagcag cgatgggctg agggcagtct ttctgtgagg atggggcagg actctgtacc 104700
caggcacagg cactggggcg ggggagggtg ctgatgacac ccactggctg aaccccaccc 104760
tgcgactgtc tggtgtcttc cagcactctg tctaccctta gctgtaggct gcttgaagtt 104820
cacaattttc actctttggc aatgtttgtt gttgaaaagg aggaacggga tgatgatgga 104880
tggctcatcg tcatccactg tgccatctgc tcttttctag gggtgttttc acgtggcagg 104940
ggcccagtgg cttctgggag ctacaacacc cctgcccctg ggttctgaca cctgttgtct 105000
cagcaccaag gtctcctgca ctgactgctc agtgagggga tggggcggga tggggcggga 105060
cagtgggaga acagaccctc ggttgagtga cacaacagca gaaggctagc tgcaggcgga 105120
gcgccatccc agaggcagag gtggggtgtc ctgcaaggca gggacgggtg tgtggagcag 105180
gaaggtcatg gtggtgctga tagcactttt aaacccctgg gggttttggc tcagcatgag 105240
taatggctat gatgtctgct cagtgtcgca cggtgaagat ctccatcctt ggggatgagg 105300
gcgtgcctgt gcaggtggac ggagaggcct gggtccagcc gccagggtac attcggattg 105360
tccacaagaa ccgggcacag acactgacca gagacagggt aagagcggct gcccgcggta 105420
cctgggtggg gtacagggct cacctgtggg ctcttgtgtg cactgttaag agctggagct 105480
ttttgtgttt tgttctagga tttttttttt ttttaagaca caatgattaa gctaataggg 105540
cagtaatttc taggaccatc tccttcccct aatgttaaaa aaaaaaaaaa gtcctatttg 105600
tctctttcta gttgtgatct cgttggcatc cccatagtgt ctgtcgcagt cagatgcatg 105660
cttcagagca gcaggtgtaa ttgggctttc gggtccatag gcatttgaga gcaccctgaa 105720
gtcctgggaa gacaagcaga agtgcgagct gccccgccct ccatcctgtt ccctgcaccc 105780
ggagatgctg tccgaggagg aggccaccca gatggaccag tttgggcagg cagcaggggt 105840
cctcattcac aggtgggctc ctacccctct gcgttgcgca tgagcctccc ccagggtccc 105900
tgggactgca ctcttccaag gcccctgggg cgtggagctg ctgctcctga cttttgtggg 105960
gtctgcatta cccatgaggg ccgagcctgt ttatgtgccc tcagctctgg ctcatttccc 106020
cagtggtctt tcagaactcg cctggagttt acatggctgg aacctaaagc ccactgtgat 106080
tttcaggacc actcgtttaa aacctgcccg ggctcagccg ggcgcggtgg ctcacgcctg 106140
taatcccagc actttgggag gccaaggtgg gcagatcaca aggtcaagag attgagacca 106200
ttctggctaa catggtgaaa ccccgtctct actaaaaata caaaaaaatt tagctgggtg 106260
tggtggcggg cgcctgtagt cccagctact ctggaggctg aagcagcaga atcagtcgaa 106320
ccccagaggc ggaggttgca gtgagccgag atagcgccac tgcactccaa cctgggcgac 106380
agagcaagac tctgcctcaa aaacaaacaa aacaaaacaa aaaaaccctg ccctggctcc 106440
cgagggcagc ccgctgacag ccgccttcac tttgccctcg ttttaccctg agaacaggct 106500
tgctctttgt tctcaagttt actttaaaaa aaaaaaaaaa aaagacaact gctggggcat 106560
ttcctctcac ctgccttcta gaaacacccc tggagccact gtgtccctcg tggctggtgg 106620
tcagcattgt ctgccattcc tgctcctcgc ccgccaggtg cgggttccgc ctgtgagtcc 106680
ctcccagccg gcagctgtgc tgctccgccg gtgcggggcc tgcctgcatt ctccccccgt 106740
ggccgcacgc tggctggtgc cctggtgtcc ctttcttgtt tcccctgggc tccttcttct 106800
cctggctgtg gacaggtgca cccgtcggtt ttgtgcccgg catgccgtgt gcccttccag 106860
gcagcctgcc cagccctggc gtgcagatgg atcgtctgtg ccagccttcg gctcttgtcg 106920
agcaggtggt cgctgtccca gtcatcaccg gcgttcctcg ctctgcactt ccataccggc 106980
tgcagtcctt cctggcgctg cattctctgc cccaggagtt ggtgccactg cggcccctgt 107040
cctcgtctct cccccacccc acccagatca gtgatggggc tggaggactt cagttcagct 107100
aattccttgc cgtgcagtgg gcttctggtg gcctcccctg gaaagccatt accctgtccc 107160
ctcaaagccc atggtggccc ctctggcctg cctggaaggt gcacttgcac agcactgcag 107220
gaagctgctg gcagcggcct gtttccacag ggtcaggaca ggctggcccc gctgcctttg 107280
cttgcactgc tcctatagtc tctgtccccc gatctcacct gcctgagcca catctcagcc 107340
tccctgggac ctggtgtgac ttgtgctctc accgtcttcc ctatgagggc tgctatctgg 107400
ggtctggctc agagcccatc actgcaccag gattgtcctg ttcagatgag ggtccttttg 107460
tccccaggga cagaccggcc agttacaggt tccagcaagg ctgtggggat tgtgccttac 107520
tgcagcagtc tctgcagtgg gcctgtgcac actgtcactt gcccactggc cgttttacag 107580
gttgtaagcc tcattttgta catttctctc cctggaaaat cttggatttt gacgtcagat 107640
ttctcgtgga agccctccca tttgctgtgg gtcatcctgt gcccaagctt gtgactgaac 107700
ggtcgctggg ctgagccacg atccctgtcg tcctgctggg cctgccctcc acatcagccc 107760
tccaggtggt acctgggccg tgttcagatg cgtattgtga aaggctgccc ttccatttgg 107820
cctgacatct gcccgtgctt ctcttcctct ctagtatccg agaaatagct cagtctcacc 107880
gggacatgga gcaggaactg gcccacgccg tcaatgccag ctccaagtcc atggaccgtg 107940
tgtatggcaa gcccagaacc acagaggtag ctattctggc cttttcagtc ctggcttctt 108000
ctcagtgtct gccgccctcg gccctccccg tgcgtgttca ttcccccgcc tccccggtgc 108060
atgttcggcc ctcccagtgc ttgttccctg cccctaaccg tgcatgttcg gccccccgcc 108120
cccatgcata tttgcctggt ttcttctagg ggctcaactg cagcttcgtc ctggaaatgg 108180
tgaataactt cagagctctg cgcagtgaga cggagctgct gctgtctggg aagatggccc 108240
tggtaagctg gtgccccagg gacagcaggg ctcgggctgt gtgtgaaacg actgctgtcg 108300
ccaggttgct gggcacacag ggcagcacac tttagtccag agttcccggt cttaaggaat 108360
gggccgcaga ggtcatttgg tttgttgtgc ggctggtgcc cacccctgct ggcaacccct 108420
cagtcaggtt gtctcaagca tgcgagaagc gcttgcagcg gaaacaccct tgtcgtcgtg 108480
gacagaagat gcttttctgc cttagaagcc tgtagtgcag agtcctgctc ctgccgagag 108540
ctggccacac tctcaggcac cttccatgct cagccctgca aaaccggctg atatggcagc 108600
tgtggggctg ttactgaatc acaggggcta gaacagggag aggcctgaga gactgactgg 108660
ccagccttct ggttttaaag atgaggagga aggggcttga taaagattgg gcaactggag 108720
aaccgcccca ggtgtggttt cccagccctc cactccgcac gccactcacc tcctcactgc 108780
acgcgtctcc tcactgcacg catcacctca ctccacacat cacctcactc cacacatctc 108840
ctcactgcac gcatctcact ccacacatca cctcactcca cacatctcct cactccacac 108900
atctcctcac tccacgcatc tcctcactcc acgcatctcc tcactccacg catctcctca 108960
ctccacgcat gtcctcactg cacgcatgtc ctcactgcac gcatgtcctc actgcacgca 109020
tgtcctcact ccacgcatct cctcactcca cgcatctcct cactccacgc atctcctcac 109080
tccacgcatc tcctcactcc acgcatctcc tcactccacg catctcctca ctccacgcat 109140
ctcctcactc cacgcatgtc ctcactgcac gcatctcctc actccacgca tcacctcact 109200
ccacgcatca cctcactcca cagaaatcct cactctacgc atctccttat cccatgcctc 109260
ccctcgtccc acgtcccgtg gtcacacgcg tgtcctcact gcacacctcc tgctgcctcc 109320
tgcaaggttc gactgctgac tttgcttccc acagcatttc cactgcttga cacaggtgaa 109380
tggctccgac cccatttctg acagagggac acaagcaggt cagttgtcag ccttgctcta 109440
tgtgaattca tcgttgactg atggacagtt ttattctctc accagcacta cttagaaagt 109500
gaggttctgg gtttggttcc ttttctggtg ctctgggact tcgtttctgg aaagtgagct 109560
ccctgatcag agcagagcag agccctggag cggacctcac ccccctgggc ctcgcgctga 109620
tcagcagtgc acactctcca tttctctctc cctccctccg cctggagcag cagctggatc 109680
cgcctcagaa ggagcagctg gggagtgctc ttgccgagat ggaccgacag ctcaggaggc 109740
tggcagacac cccgtggctc tgccagtccg cagagcccgg cgacgaagag gtatgtggct 109800
catagggctg tgcctgggtc tcccggacat ggtggctctc gcctgaagtg cctgtgttcc 109860
ttgtgacccg tgtggctctg ggatcaagat cgtgtcgctc cggcagcccc tgaggggcct 109920
tctccagact tcgctattaa aatgctcttt aaggcaggga gggacagcag gtaggaagga 109980
gttctgggct gggattaaga gtgccccttg aggaccaggg acctgttgtc ctctgaaaca 110040
gaactgcagg gcttcctgga cagtgggtag aaggaaggct gagcccagcc ccacagcctc 110100
ccccgagggt ggagatgtat catgggataa atggcagcct tttgggatcc cgctgtggac 110160
agggcgcagt tggtgtgcgc cactccccac tcacactctc ttcctgtgtg aacagaaaga 110220
ctccagctcg tcgcaggtct gggagggacc cgaggacgca gggcatagcg gaccctgggg 110280
tggagtcaca ttcttctgca gggagtgctg gctgaaggag ccctggagag ggccgtgtct 110340
ggacaaggac aaaccccagc ctgtctcttg gcttccctgc ttcagagata gaacacagag 110400
gggccctgag gaaagctcat cttgggcagt acagttgcag aaggcaaata actgcaagac 110460
gccaaacctg ggcacccctg cccagtgggg tttgtgagac ctgtgggcag cagtaaggcg 110520
aggggacaga ggtgggcagc tgcacaacag caccctcttt ccggggccct ggggcgtttt 110580
ttgacgcatg caatcctttc atgggaaact gactcaggca ctccagccga tggatgaaac 110640
tcagcagctt ctcagtgagg gcacttgggt ataaaaggac agggcaagct cctcaaaatc 110700
cattaaataa ttcattgtaa aggtgattaa gaaattttac ccaaaattac aaaaataata 110760
atatacaatg attcaacaga tgtcacagtg acatagccct ataataccag attaaattaa 110820
ggccagtaaa gtgggcagtg aggtgagagg ctgggaagag gacatggacg gggggaggaa 110880
agcatgttaa attcctcctc ttacagtgga agaacgttac aaacaacatt cttgactttc 110940
atacttggag aaatacagag tcaataatgt ttttagggtc aagagtggtg gctcgcacct 111000
gtaatcccag cactttggaa ggccaaggtg ggaggatcac gttagccgag gagttcaaga 111060
ccaggctcgg caacatagtg agaccctgtc tctattaaaa aaaaattttt ttttaaactt 111120
aaaggtaatt tctaatagag ctgaaaagat ttatatcttc caaattgcca ccaaggacaa 111180
aaataaaata caatttatat tgtaaaagaa agtaaaggac cagcaagggt atcgctaaca 111240
gcatgaaaat aagataacag aaaaatgaca tggctttctc ttaaaagtaa attcttaggt 111300
tgtgttttaa aagaaaccta accatatatt gctcacaaga gccctgtttt tttttctcat 111360
actcctaata aaaatttatg atacagaaag attaataata attaaaacac cataaaaaat 111420
ccaaagtaac aatataaaaa taaaattgca tatgtaagac aataaatgat aaaaagagga 111480
tcactttaca ttggtaaaat acaataattg ttatgtatag tcatcaactt atgacagtta 111540
taatagtcac gaaactgtgc caaataataa gcatctaaat tagctgttca agactatgtt 111600
ttttattccc taacttcatt ttactgtgct ccaagcaatg gtctgtatgt tactagtcct 111660
ttgaaatgta ctgaggtgag acttgcccaa taggtggttt ttgtaaatgt atcttgtatg 111720
cagttgtgtt tacatcatta agttcctact gaaatttttt ttgtcttctt gatagatcag 111780
ttaactctaa taccataatt gtagatgtct cagtttatct ttgtggttat gtgtattttt 111840
gcttcatgta ttttgaggct atgttattgg gtacccatag gttttatcat tatataatga 111900
tccttttatc tttagtaatt ctttttatct tcaagtctac ttgcttgcta tattttttca 111960
tagttttact ttcaagcttt atttggagtg tctcttataa agagtgcatc acagagtgag 112020
gcagtgttac ctccgtgcat ctcagggagt gctgtgtgga gaggctgccg ccgccgatgg 112080
ctgtcaagag cagaggccga gcctctgtgt ggctccgctc ttcacccttc ctctgctctt 112140
ctgcctcagg gagtggatcg caaggaaaga atgcaaagtg caggagagtt ttcattagac 112200
agatactcgt aatactaaga atcaaagccc agcaatccaa cactagaaga ttggctaaag 112260
aggttatttt aataattttt gtttagatac tgatatttat gatattttca aaaagttttt 112320
aaatctcatg agaaacgcac atgtaaagtg aaggaagtag aatatgataa aaatagacac 112380
tatgatcact ttgaaaccac tttaacactc actaaaatca acactaaata caagaatcaa 112440
taagggagag aagccctttc aggcacaaga ggtctttccc agctcccgct catctcagcc 112500
ctgcctgccc tcccagcctc tctggtggag atgggcatga ggccgtgatc agttgcagcc 112560
tgattctcag tattcctcat tctccccaac agagtgtgat gctggatctt gccaagcgca 112620
gtcgcagtgg taaattccgc ctcgtgacca agtttaaaaa ggagaaaaac aacaagaaca 112680
aagaagctca cagtagcctg ggagccccgg gtacctgcct ctctcccgcg tgtgtttctg 112740
gccgtccacg cctgctggat cggccccgtt cccctggtct ctgctttctc ccttggcctt 112800
gcagctcctc cctcttggtc cctgtgctgt aacccccggt cctgcgacca cacttgtctg 112860
ttggtagctg cagccctcca ccctgcctgc ttcccctctg accgttgtca cacccggccc 112920
tgacgtgctc tctggctttc tgcctgccct gagttggggg attcgaggtg gggaggaaga 112980
cagcagtaga gtggtgacaa gacaaacttg gagacacaaa gctctggact caggccgtgc 113040
tggggcatgc cctgcctgct ccctcctggg ctgctggttc ctgataaatt gatgcattgg 113100
tcgaggttcc tgtgctggga agcccaggcc accagagatt gtgggtgatg aaatcaatcg 113160
aatatggtcc tgaaggacat tgttcctttg ggtcagtaaa ttggagctaa actctctgtc 113220
tgaaggatca gccctgaata cccaggccat atccagtgct gtcaggggct ggagaggcct 113280
ccaagcctgg atattgggac tggtgtttgc cgccagtcag ggcagctcct gtgggttttt 113340
cttctttgca tgtttgtcca gaaatggggt ttctgttaat aatggtggct ctgactatgt 113400
gaattgaaat ctctgctcgt ttcctttcct gctatggtcc agaagtgaaa tttaaccctt 113460
ctagaagctg gaggaaaagc tggctttggc cacaatcatg aggacatttc cctcatattt 113520
ggtggtggta aatccctcct gggacacggg gaaatgacca gaggctggcg gcccacctgg 113580
caggaacaga tgccagctct gctgcagcca tcgccccttg agcgggtggc tctgtgcctc 113640
tttctgcact gctggtgggt ggtgctgttg gctgggtgat ggataccggc tgccagagat 113700
ggctcaggtg ccagctgctg ggctatctca ggcactggct gctgggctat ctcgggtgcc 113760
ggctgctggg ctatctcagg cgctggctgc tgctgggctg tctcgggtgc tggctgttgg 113820
gacgtctcct gtcctggcac tgggctctcg ggtgctgggt gccagctgct gcctaccttg 113880
cactgggctc tgggcactca ctgcactcgt gcttttccat ctccgacagt tcacctctgg 113940
gggacagagg aggttgctgc ctggctggag cacctcagtc tctgtgagta taaggacatc 114000
ttcacacggc acgacatccg gggctctgag ctcctgcacc tggagcggag ggacctcaag 114060
gtacttccat aggcgtctcc ctggaacctg cacttgggct tgcacgcagc tcccttctct 114120
tccatcctct cccccgacct ggccatgtcc cagcatcacg attcttctca ggctttcgtg 114180
tatacctcag gtgggggcgg ctgtggccct catctaggca gtgatggctc cacccaccac 114240
aaccagagga agccaggagc agacataatg gggggcagag ccttggttat cttaggctac 114300
tcagacaagg actgtcttcg tgttaaaaac actatgaggg gacacagacc ctgaagcaca 114360
gtcacacacg actgtcccca tgctgctcct gggcgggtgc tgccactcgt ctgcagggag 114420
cattgggagg ggtggttggg tgccaggcct cggtctatgc caggcctcac gccacatctt 114480
gcaggcccat gcccctgccc aggttggcct caacgggcca acccctgggt gttgaatcac 114540
tggctgagtc ccgagagggc aaaaggccac tgtgggtgtc ctggacagtg gctctcatga 114600
ggtcacttgt catccacttg cttttaggcc tgtgttttgt ctttgtcttg gatttgtcct 114660
tgctgatggt agtgactaga atgcaggaac aatgggccag gcatctgtat ggttgttact 114720
tttaagctgt ttccatcttg ttttaccgtt tttgtcattt tggctctcat ttgtgttcac 114780
aagccgaatg ggaagggccg ttgtggcagg cctgctgtgg agccctctgg ccctggctgt 114840
cttctcggca tccatggcgg tgtcttctct gttgcaggac ctgggcgtga ccaaggtggg 114900
ccacatgaag aggatcctgt gtggcatcaa ggagctgagc cgcagcgccc ccgccgtcga 114960
ggcctagcct ctgtcctctc agcctgtggc ctccacatcc ccgccgccga ggcctagcct 115020
ccgccctctc agcctgtggc ctctgcgcct cctgccactg aggccctggg cagatgctgc 115080
agcccgcccc cttctcatgg tgctacttcc tctgtcagct acagaaagcc tccgtgacac 115140
cgtccaccag agctctgggg tctcgaacat aacaacacag ctacctttga aacaacactt 115200
tctccagctc agagtcacct ggggcacatg tgtcacggcc actcagctct cgcccgcctg 115260
tgctgtgggc cagggaatcc agcggcgtct ggcctcctgg gcactgcttg cctggcctcg 115320
tgcttggatt gtcccggggg ctcctctccg tgtgtccttc tgtggccgca ccgtgtggct 115380
ccgcctcctg gcccccagcc agttctcaga aacgtggctg gggcccagca cagcagcctg 115440
caagggcccc tgtttgttga tgcagctttt gttgaacaaa aatcgtgctc tttcctggtt 115500
tgaaagtagc atggatgttt ccagtcttgt tgattgtaat ttgacgtgaa gagaaaaaaa 115560
aattcctcct gcgtgagcca aggcagcggg tgctgtttcc caggcgggga gcccctccct 115620
gggtgtcaca gggcctgtgc tcctccctcc tccatcctct ctcctcccgc tcctccctcc 115680
ccccactgtg ggctggggac gcctgccctt ctgtctccgg acgctctagg cgagttcagc 115740
ttggggtgtg agtgagacag cttgccagct gcatccctgc agacagagga tgtgtgtcca 115800
catgagtgtt tctgtgtggg aaatgcttcc tggctctggg aaactttttc tgcccattct 115860
gtggttccca gggagcgtgg ccctggtggg ccaggggtgg tttgacctct tcagcccgtc 115920
cggtggcctg gaggccggag gctctcctga gtgtctgccc ctgcagtggc ttcttgtcgc 115980
ctgctgctgg gcgtgatgtc gctggaggtg ctggcaggga ctctgatttg gtggtccgcg 116040
ctgcccctgc cctgcctctg tcctggctct gaactagtag atgatggtgc cagagggcag 116100
ggagctcgcc tggggagagg gctgtgcccc gtagggacag tgcccaggtg aaggatgccc 116160
ctggtcctcc agggcactga ctttgccctt ttttcccgtt gatagtcatg gctcagaggt 116220
gcttgtaaat gtcttgggaa gaggtttctg taacccctgc cctggtgtga ggaggaaatg 116280
gctctggcct ggctgcctgg ccgtggcttc tctttggctc ccaaagagaa ggacagtgtt 116340
gggagtatct gccgtggctt ctctttggct cccaaagaga aggacagtgt tgggagtatc 116400
tgccggcgct gtccaggtcc tttagtcagc gtcactccat ctgatgtgca gaagctgggc 116460
tgcacctgcg ggggtgggca tagaccgggc tgggtctgca gcagcccctg gtcctgagca 116520
ggcggcagtg aacagcactg gcccacctcc cactcacagc ccctctgtcc cctctgcagt 116580
gcacccaggt gggcccctct gcgtgccttt gggtgctccc ctctcgtggt cgttctggcc 116640
cgaggccctt agagtatgga ggctgagcca ggccttgggt ttccccagca cagcctcctg 116700
tcgctgcatg cgacgtgttg ggatttttgg atgaaagact ctcccacgct ctgttggtgg 116760
acttagctgc ctcactggaa gtgatgtggg tggaaggtgg ttgtatgtta ccttttccac 116820
ctctcattgt tttccccaga acattgtaga tgggggttgg cagagggaga aataagccag 116880
ccacggcagt cgcttggttt cccaggtgga atgggctaac acaggagatg atgggaacct 116940
gtcccgcagt ccctgcatga ccattggccc tgctggcctg gcgatgtggg catcctgggg 117000
ttcttagggt cccagaacaa gccccaggca agctggaact tgggtgggga ggggacatga 117060
ggaggataaa cagctgactg tggcttcaag gacatcaggg ccaccccaag tcctcagtgt 117120
cctactcctg gcaaggagtt gggtttggat caaaagtgtt taaaattaat atgttgtcag 117180
tgattagaac aacactgttt acataaaaac catttttcta attctaacaa gttagaatgt 117240
gaggaaggaa tgaacatgag tgtttaggaa cctgcccttt ggtgctgggc tggcgtcccg 117300
cactggggtg tcctcgctgt ctgggggctg ctctgctgcc ccggcccagg tccccttgtg 117360
gtgttgccag acgggcctca tggtctgctg tgcagagaga ggcaggaagg atccctgaag 117420
agtcttggag aaaaggttct gtgccctcag gtggggctta ccccctcgta tttataatct 117480
taatttatat agtgaccacc gtggaaacaa acgcctcttg tattgtcatg tacatagtcc 117540
atacctgagt gctgtacata agttgttctg tgtataaata aaacaagcct gtttttgatc 117600
ttcca 117605
<210> 2
<211> 20
<212> DNA
<213> Artificial Sequence
<400> 2
tctgacagat gccagcgtag 20
<210> 3
<211> 21
<212> DNA
<213> Artificial Sequence
<400> 3
actgttgttg acgtttttgg t 21
<210> 4
<211> 20
<212> DNA
<213> Artificial Sequence
<400> 4
catggaccac ttctcaggga 20
<210> 5
<211> 21
<212> DNA
<213> Artificial Sequence
<400> 5
ctcacggcac acattgcagt a 21
Claims (10)
1. An isolated nucleotide containing a new mutation site, the sequence of the nucleotide is shown as SEQ ID NO.1, the new mutation site is located at 35949 th position rs542595931 as G-A and 80316 rd position rs1345260651 as A-G.
2. Use of the isolated nucleotide containing a new mutation site according to claim 1 as a molecular marker for congenital heart disease or for the preparation of a reagent or kit for assisting in screening or detecting congenital heart disease.
3. The use according to claim 2, wherein the reagent comprises a primer, a probe, a chip or an antibody.
4. The use according to claim 2, wherein the kit contains one or more reagents selected from the group consisting of:
(a) Specific primers for detecting one or both of said novel mutation sites;
(b) A specific probe for detecting one or both of said novel mutation sites;
(c) A chip for detecting one or two of the new variation sites;
(d) And the specific antibody is used for detecting the mutation of one or two amino acids corresponding to the new mutation sites.
5. The use of claim 3 or 4, wherein the new mutation site is located at position 35949, rs542595931 is g→a, and the primer is:
forward primer 5'-TCTGACAGATGCCAGCGTAG-3' SEQ ID No.2,
reverse primer 5'-ACTGTTGTTGACGTTTTTGGT-3' SEQ ID No.3;
the new mutation site is positioned at 80316 th site, rs1345260651 is A-G, and the primer is:
forward primer 5'-CATGGACCACTTCTCAGGGA-3' SEQ ID No.4,
the reverse primer 5'-CTCACGGCACACATTGCAGTA-3' SEQ ID No.5.
6. A kit for aiding in the screening or detection of congenital heart disease, said kit comprising: primer pairs designed according to the new mutation sites rs542595931 and rs1345260651 of the sequence shown as SEQ ID No. 1.
7. The kit of claim 6, wherein the new mutation site is located at position 35949, rs542595931 is g→a, and the primer pair is:
forward primer 5'-TCTGACAGATGCCAGCGTAG-3' SEQ ID No.2,
reverse primer 5'-ACTGTTGTTGACGTTTTTGGT-3' SEQ ID No.3;
the new mutation site is positioned at 80316 th site, rs1345260651 is A-G, and the primer pair is:
forward primer 5'-CATGGACCACTTCTCAGGGA-3' SEQ ID No.4,
the reverse primer 5'-CTCACGGCACACATTGCAGTA-3' SEQ ID No.5.
8. A method of using the kit of claim 6 or 7 for non-diagnostic purposes, comprising the steps of:
s1, extracting DNA of three family samples;
s2, amplifying by using the primer pair to obtain an amplified product;
s3, detecting whether new mutation sites rs542595931 and rs1345260651 shown in SEQ ID NO.1 exist in the family child sample by adopting a Sanger sequencing method.
9. The method of claim 8, wherein the total volume of the amplified amplification reaction system is 50. Mu.l, wherein,
amplification PCR reaction conditions: 94 ℃ for 2mins;40× (94 ℃ 30s;58 ℃ 30s,72 ℃ 30 s); and at 72℃for 10mins.
10. A special primer pair for detecting SNP locus containing new variation locus nucleotide is characterized in that the nucleotide sequence is shown as SEQ ID NO.1,
the new mutation site is positioned at 35949 th site, rs542595931 is G-A, and the primer pair is:
forward primer 5'-TCTGACAGATGCCAGCGTAG-3' SEQ ID No.2,
reverse primer 5'-ACTGTTGTTGACGTTTTTGGT-3' SEQ ID No.3;
the new mutation site is positioned at 80316 th site, rs1345260651 is A-G, and the primer pair is:
forward primer 5'-CATGGACCACTTCTCAGGGA-3' SEQ ID No.4,
the reverse primer 5'-CTCACGGCACACATTGCAGTA-3' SEQ ID No.5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111631423.XA CN116355923A (en) | 2021-12-28 | 2021-12-28 | New mutation site of congenital heart disease related DGKD gene and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111631423.XA CN116355923A (en) | 2021-12-28 | 2021-12-28 | New mutation site of congenital heart disease related DGKD gene and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116355923A true CN116355923A (en) | 2023-06-30 |
Family
ID=86911325
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111631423.XA Pending CN116355923A (en) | 2021-12-28 | 2021-12-28 | New mutation site of congenital heart disease related DGKD gene and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116355923A (en) |
-
2021
- 2021-12-28 CN CN202111631423.XA patent/CN116355923A/en active Pending
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