CN116324424A - 流式细胞仪、细胞分选仪、光学信息生成方法和程序 - Google Patents

流式细胞仪、细胞分选仪、光学信息生成方法和程序 Download PDF

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Publication number
CN116324424A
CN116324424A CN202180055235.9A CN202180055235A CN116324424A CN 116324424 A CN116324424 A CN 116324424A CN 202180055235 A CN202180055235 A CN 202180055235A CN 116324424 A CN116324424 A CN 116324424A
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China
Prior art keywords
flow path
signal detection
optical signal
light
optical
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CN202180055235.9A
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English (en)
Chinese (zh)
Inventor
今井亨
安达启晃
户田圭亮
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New Xite Corp
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New Xite Corp
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Publication of CN116324424A publication Critical patent/CN116324424A/zh
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N15/1436Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484Optical investigation techniques, e.g. flow cytometry microstructural devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N2015/0294Particle shape
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1447Spatial selection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497Particle shape

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN202180055235.9A 2020-10-15 2021-10-15 流式细胞仪、细胞分选仪、光学信息生成方法和程序 Pending CN116324424A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2020-174037 2020-10-15
JP2020174037 2020-10-15
JP2021110063 2021-07-01
JP2021-110063 2021-07-01
PCT/JP2021/038306 WO2022080492A1 (ja) 2020-10-15 2021-10-15 フローサイトメータ、セルソータ、光学情報生成方法、及びプログラム

Publications (1)

Publication Number Publication Date
CN116324424A true CN116324424A (zh) 2023-06-23

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CN202180055235.9A Pending CN116324424A (zh) 2020-10-15 2021-10-15 流式细胞仪、细胞分选仪、光学信息生成方法和程序

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Country Link
US (1) US20230266229A1 (https=)
EP (1) EP4230995A4 (https=)
JP (1) JPWO2022080492A1 (https=)
CN (1) CN116324424A (https=)
WO (1) WO2022080492A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024066938A (ja) * 2022-11-02 2024-05-16 シスメックス株式会社 光学システムおよび検体分析装置
JP2026507735A (ja) * 2022-12-20 2026-03-05 ビット グループ フランス 単一の非コヒーレント光源から発せられるビームを分割することによって蛍光及び散乱を測定する光学フローサイトメータ

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090059223A1 (en) * 2007-09-04 2009-03-05 Sony Corporation Light irradiation method, light irradiation device, and fine particle analyzing apparatus
EP2085763A2 (en) * 2008-01-30 2009-08-05 Palo Alto Research Center Incorporated Obtaining Sensing Results and/or Data in Response to Object Detection
CN102439416A (zh) * 2009-03-20 2012-05-02 伯乐实验室有限公司 串行线扫描编码多色荧光显微术及成像流式细胞仪
CN104136939A (zh) * 2012-02-28 2014-11-05 皇家飞利浦有限公司 用于使正电子发射断层摄影(pet)检测器模块同步的方法和系统
CN105008895A (zh) * 2012-10-15 2015-10-28 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
US20190302000A1 (en) * 2016-06-10 2019-10-03 The Regents Of The University Of California Image-based cell sorting systems and methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH073419B2 (ja) * 1986-10-07 1995-01-18 東亜医用電子株式会社 流体中の細胞分析方法および装置
US9134221B2 (en) * 2009-03-10 2015-09-15 The Regents Of The University Of California Fluidic flow cytometry devices and particle sensing based on signal-encoding
JP5534214B2 (ja) 2009-10-05 2014-06-25 ベイバイオサイエンス株式会社 フローサイトメータおよびフローサイトメトリ方法
EP3198243B1 (en) 2014-09-30 2020-07-22 The Regents of the University of California Imaging flow cytometer using spatial-temporal transformation
GB2592113B (en) * 2018-06-13 2023-01-11 Thinkcyte Inc Methods and systems for cytometry
DE102019107327A1 (de) 2019-03-21 2020-09-24 Specs Surface Nano Analysis Gmbh Vorrichtung und Verfahren zum Elektronentransfer von einer Probe zu einem Energieanalysator und Elektronen-Spektrometervorrichtung
JP7496689B2 (ja) 2020-01-10 2024-06-07 Jfe建材株式会社 保護具

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090059223A1 (en) * 2007-09-04 2009-03-05 Sony Corporation Light irradiation method, light irradiation device, and fine particle analyzing apparatus
EP2085763A2 (en) * 2008-01-30 2009-08-05 Palo Alto Research Center Incorporated Obtaining Sensing Results and/or Data in Response to Object Detection
CN102439416A (zh) * 2009-03-20 2012-05-02 伯乐实验室有限公司 串行线扫描编码多色荧光显微术及成像流式细胞仪
CN104136939A (zh) * 2012-02-28 2014-11-05 皇家飞利浦有限公司 用于使正电子发射断层摄影(pet)检测器模块同步的方法和系统
CN105008895A (zh) * 2012-10-15 2015-10-28 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
US20190302000A1 (en) * 2016-06-10 2019-10-03 The Regents Of The University Of California Image-based cell sorting systems and methods

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EP4230995A1 (en) 2023-08-23
WO2022080492A1 (ja) 2022-04-21
JPWO2022080492A1 (https=) 2022-04-21
EP4230995A4 (en) 2024-11-13
US20230266229A1 (en) 2023-08-24

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