CN116270948A - 一种治疗关节病的中药组合物及其制备方法和应用 - Google Patents
一种治疗关节病的中药组合物及其制备方法和应用 Download PDFInfo
- Publication number
- CN116270948A CN116270948A CN202111585518.2A CN202111585518A CN116270948A CN 116270948 A CN116270948 A CN 116270948A CN 202111585518 A CN202111585518 A CN 202111585518A CN 116270948 A CN116270948 A CN 116270948A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- chinese medicine
- traditional chinese
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 50
- 239000003814 drug Substances 0.000 title claims abstract description 46
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 208000036487 Arthropathies Diseases 0.000 title claims abstract description 10
- 208000012659 Joint disease Diseases 0.000 title claims abstract description 10
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 35
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 19
- 229940116229 borneol Drugs 0.000 claims abstract description 19
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 19
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 19
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 18
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 18
- 241000903946 Clematidis Species 0.000 claims abstract description 17
- 241000239226 Scorpiones Species 0.000 claims abstract description 17
- 208000020084 Bone disease Diseases 0.000 claims abstract description 14
- 239000004863 Frankincense Substances 0.000 claims abstract description 14
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 10
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 10
- 241000255789 Bombyx mori Species 0.000 claims abstract description 9
- 235000003717 Boswellia sacra Nutrition 0.000 claims abstract description 9
- 240000007551 Boswellia serrata Species 0.000 claims abstract description 9
- 235000012035 Boswellia serrata Nutrition 0.000 claims abstract description 9
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 9
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 9
- 244000273928 Zingiber officinale Species 0.000 claims abstract description 9
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 9
- 235000008397 ginger Nutrition 0.000 claims abstract description 9
- 241000382455 Angelica sinensis Species 0.000 claims abstract description 8
- 235000002566 Capsicum Nutrition 0.000 claims abstract description 8
- 244000018716 Impatiens biflora Species 0.000 claims abstract description 8
- 235000015912 Impatiens biflora Nutrition 0.000 claims abstract description 8
- 244000170916 Paeonia officinalis Species 0.000 claims abstract description 8
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 8
- 239000006002 Pepper Substances 0.000 claims abstract description 8
- 235000016761 Piper aduncum Nutrition 0.000 claims abstract description 8
- 235000017804 Piper guineense Nutrition 0.000 claims abstract description 8
- 235000008184 Piper nigrum Nutrition 0.000 claims abstract description 8
- 235000005155 Tanacetum balsamita Nutrition 0.000 claims abstract description 8
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 8
- 235000011477 liquorice Nutrition 0.000 claims abstract description 8
- 244000203593 Piper nigrum Species 0.000 claims abstract 4
- 238000002156 mixing Methods 0.000 claims description 27
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 14
- 241000180649 Panax notoginseng Species 0.000 claims description 14
- 241000951473 Schizonepeta Species 0.000 claims description 13
- 239000011259 mixed solution Substances 0.000 claims description 13
- 238000002791 soaking Methods 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 10
- 238000000227 grinding Methods 0.000 claims description 9
- 238000005303 weighing Methods 0.000 claims description 9
- 241001506371 Kadsura Species 0.000 claims description 7
- 241000112528 Ligusticum striatum Species 0.000 claims description 6
- 240000005717 Dioscorea alata Species 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 4
- 244000061520 Angelica archangelica Species 0.000 claims description 3
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 2
- 206010028289 Muscle atrophy Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 208000002193 Pain Diseases 0.000 abstract description 33
- 230000036407 pain Effects 0.000 abstract description 31
- 230000017531 blood circulation Effects 0.000 abstract description 18
- 239000008280 blood Substances 0.000 abstract description 16
- 210000004369 blood Anatomy 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 15
- 210000002435 tendon Anatomy 0.000 abstract description 10
- 230000003213 activating effect Effects 0.000 abstract description 9
- 230000008961 swelling Effects 0.000 abstract description 7
- 230000002040 relaxant effect Effects 0.000 abstract description 4
- 230000004089 microcirculation Effects 0.000 abstract description 3
- 210000003205 muscle Anatomy 0.000 abstract description 3
- 241001506304 Kadsura japonica Species 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 description 14
- 241000522620 Scorpio Species 0.000 description 10
- 208000014674 injury Diseases 0.000 description 10
- 239000009490 scorpio Substances 0.000 description 10
- 208000006820 Arthralgia Diseases 0.000 description 8
- 201000008482 osteoarthritis Diseases 0.000 description 7
- 230000008736 traumatic injury Effects 0.000 description 7
- 206010042674 Swelling Diseases 0.000 description 6
- 241000717739 Boswellia sacra Species 0.000 description 5
- 208000005392 Spasm Diseases 0.000 description 5
- 210000000988 bone and bone Anatomy 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 241000255791 Bombyx Species 0.000 description 4
- 241000628997 Flos Species 0.000 description 4
- 240000003889 Piper guineense Species 0.000 description 4
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 208000034783 hypoesthesia Diseases 0.000 description 3
- 208000008035 Back Pain Diseases 0.000 description 2
- 241001522633 Betula utilis subsp. albosinensis Species 0.000 description 2
- 239000008830 Carthamus tinctorius Honghua extract Substances 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 241001632410 Eleutherococcus senticosus Species 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010019345 Heat stroke Diseases 0.000 description 1
- 235000017443 Hedysarum boreale Nutrition 0.000 description 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 206010023232 Joint swelling Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010050031 Muscle strain Diseases 0.000 description 1
- 206010029174 Nerve compression Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 244000236658 Paeonia lactiflora Species 0.000 description 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 229920000175 Pistacia lentiscus Polymers 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 235000017276 Salvia Nutrition 0.000 description 1
- 240000007164 Salvia officinalis Species 0.000 description 1
- 241000434639 Speranskia tuberculata Species 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 229940126673 western medicines Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
本发明公开了一种治疗关节病的中药组合物及其制备方法和应用，中药组合物包括以下重量份组份：威灵仙40‑60、红花40‑60、川乌40‑60、草乌40‑60、甘草40‑60、冰片40‑60、骨碎补40‑60、黄芩40‑60、当归40‑60、全蝎40‑60、僵蚕40‑60、丹参30‑50、全虫40‑60、干姜30‑50、乳香30‑50、三七30‑50、透骨草20‑40、海风藤20‑40、独活20‑40、川芎30‑50、白芍30‑50、荆芥30‑50、穿山龙30‑50、五加皮30‑50、络石滕30‑50。本申请的治疗关节骨病的中药组合物，其具有舒筋通络、消肿止痛、活血化瘀、改善微循环的作用。
Description
技术领域
本发明涉及医药健康保健技术领域，特别涉及一种治疗关节病的中药组合物及其制备方法和应用。
背景技术
关节骨病多是由于外伤、恶劣天气或自身姿势不正确的情况下，多年积累而造成的，轻则内伤淤痛，关节疼痛，重则行动不便，甚至瘫痪。
目前常见的治疗方法是针灸理疗、中西药物或是手术，这些治疗方案中或是治标不治本、或是治疗时间长，或是产生药物副作用，或是伤者行动受限，影响正常生活。
因此，需要一款能够满足需要的药物。
发明内容
本发明所要解决的技术问题是提供一种治疗关节病的中药组合物及其制备方法和应用，其有舒筋通络、消肿止痛、活血化瘀、改善微循环的作用。
本发明所要解决的技术问题是通过以下技术方案来实现的：
一种治疗关节病的中药组合物，包括以下重量份组份：威灵仙40-60、红花40-60、川乌40-60、草乌40-60、甘草40-60、冰片40-60、骨碎补40-60、黄芩40-60、当归40-60、全蝎40-60、僵蚕40-60、丹参30-50、全虫40-60、干姜30-50、乳香30-50、三七30-50、透骨草20-40、海风藤20-40、独活20-40、川芎30-50、白芍30-50、荆芥30-50、穿山龙30-50、五加皮30-50、络石滕30-50。
优选地，包括以下重量份组份：威灵仙45-55、红花45-55、川乌45-55、草乌45-55、甘草45-55、冰片45-55、骨碎补45-55、黄芩45-55、当归45-55、全蝎45-55、僵蚕45-55、丹参35-45、全虫45-55、干姜35-45、乳香35-45、三七35-45、透骨草25-35、海风藤25-35、独活25-35、川芎35-45、白芍35-45、荆芥35-45、穿山龙35-45、五加皮35-45、络石滕35-45。
优选地，包括以下重量份组份：威灵仙50、红花50、川乌50、草乌50、甘草50、冰片50、骨碎补50、黄芩50、当归50、全蝎50、僵蚕50、丹参40、全虫50、干姜40、乳香40、三七40、透骨草30、海风藤30、独活30、川芎40、白芍40、荆芥40、穿山龙40、五加皮40、络石滕40。
优选地，还包括医学上可以接受的辅料。
一种治疗关节病的中药组合物的制备方法，包括以下步骤：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮20-40min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀，即得中药组合物。
一种药酒，该药酒包含权利要求1-4任一所述的中药组合物，所述药酒的制备方法如下：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮20-40min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀；
(5)向将步骤(4)的混合液中加入白酒，密闭浸泡6个月后，过滤，获得药酒。
使用时将上述药酒涂于患处即可。
一种中药组合物在制备用于治疗各种关节骨病药物或腰肌劳损症药物中的应用。
本申请的药效特征如下：
威灵仙：辛、微苦、性温、小毒、归膀胱、肝经、具有祛风除湿、通经止痛的功能，主治风湿痹痛、肢体麻木、筋脉经软。
红花：苦、湿，具有活血化痰、通经止痛的功能，主治痛经、恶露不行、症瘕痞块、跌打损伤。与威灵仙搭配具有活血养血，祛风通络之功。
川乌：辛、苦、热，祛风除湿，用于风寒湿痹、关节疼痛、心腹冷痛。与威灵仙、红花搭配，可治疗局部疼痛，关节炎。
草乌：祛风除湿，温经止痛。
甘草：热解毒之功。
冰片：清香宣散，具有开窍醒神，清热散毒。与川芎搭配，行气开郁，祛除风燥湿，活血止痛。配全蝎及冰片，可用于通络止痛。
骨碎补：具有散瘀止痛、接骨续筋。与乳香搭配可治疗跌打损伤，筋骨损伤，活血化瘀，消肿止痛。
黄芩：清热燥湿，泻火解毒，止血。与荆芥搭配，治疗风湿。
当归：补血；活血，肌肤麻木。与威灵仙搭配具有活血止痛之功。配独独活祛邪以除痹痛，当归养血以荣经脉。二药合用，使荣气内充，风邪外解，而经脉清和，营血灌注。
全蝎：息风镇痉，通络止痛，攻毒散结。配冰片，可用于通络止痛。
僵蚕：息风止痉，祛风止痛，化痰散结。
丹参：活血祛瘀，通经止痛。配当归，可活血化瘀。
全虫：息风镇痉，通络止痛，攻毒散结。配当归，活血散瘀。
干姜：温中散寒，回阳通脉，温肺化饮。配威灵仙、冰片，可用于治疗膝关节肿痛。
乳香：活血行气止痛，消肿生肌。骨破碎配乳香可治疗跌打损伤，筋骨损伤，活血化瘀，消肿止痛。
三七：具有散瘀止血，消肿定痛的功能，主治咯血、吐血、便血、崩漏、补伤出血、胸腹刺痛、跌打肿痛。
透骨草：祛风除湿，该品辛温，辛能行散，温胜寒湿。舒筋活络，活血止痛。
海风藤：用于风寒湿痹，肢节疼痛，筋脉拘挛，屈伸不利。海风藤与三七、红花同用，可用于跌打损伤，瘀肿疼痛者。
独活：祛风除湿，通痹止痛。配荆芥，可祛湿，而止疼痛，同时祛风散寒化湿，经络宜通。
川芎：行气开郁，祛除风燥湿，活血止痛。配全蝎及冰片，可用于通络止痛。
白芍：养血调经、柔肝止痛，敛阴止汗、平抑肝阳。配当归、红花，可养血、不学以及活血之功效。
荆芥：解暑、发汗发热、防治中暑。治疗风湿，以荆芥配黄芩为最。
穿山龙：祛风除湿；活血通络；止咳。主风湿痹前；肢体麻木；胸痹心痛；慢性气管炎；跌打损伤。穿山龙配独活，散风祛湿，善治下部风湿，祛风散寒力胜；穿山龙配络石藤，二药合用，能祛风湿，入肝经活血通络，常用于风湿痹痛，腰腿疼痛，肢体麻木。
五加皮：有祛风湿，补益肝肾，强筋壮骨，利水消肿的作用。配川芎，强筋壮骨。
络石滕：用于风湿热痹，筋脉拘挛，腰膝酸痛，喉痹，跌扑损伤。络石藤配五加皮，可治疗关节炎。
本发明上述技术方案，具有如下有益效果：
本申请的治疗关节骨病的中药组合物，其具有舒筋通络、消肿止痛、活血化瘀、改善微循环的作用。
本申请的配方严格按照中医理论组合，配方合理，君臣佐使搭配合理，配方之间可以协同增效发挥作用，且中药组合物无毒副作用。
本申请的配方制备方法简单，可根据需要制成多种剂型，如口服剂型、外敷剂型、膏药剂型等等，使用方便。
具体实施方式
下面对本发明的具体实施例进行详细描述，以便于进一步理解本发明。
以下实施例中所有使用的实验方法如无特殊说明，均为常规方法。以下实施例中所用的材料、试剂等，如无特殊说明，均可通过商业途径获得。
实施例1
一种治疗关节骨病的中药组合物，包括以下重量组份(单位为g)：威灵仙40、红花60、川乌40、草乌60、甘草40、冰片60、骨碎补40、黄芩60、当归40、全蝎60、僵蚕40、丹参50、全虫40、干姜50、乳香30、三七50、透骨草20、海风藤40、独活20、川芎50、白芍30、荆芥50、穿山龙30、五加皮50、络石滕30。
上述治疗关节病的中药组合物的制备方法，包括以下步骤：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮20min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀，即得中药组合物。
实施例2
一种治疗关节骨病的中药组合物，包括以下重量组份(单位为g)：威灵仙60、红花40、川乌60、草乌40、甘草60、冰片40、骨碎补60、黄芩40、当归60、全蝎40、僵蚕60、丹参30、全虫60、干姜30、乳香50、三七30、透骨草40、海风藤60、独活40、川芎30、白芍50、荆芥30、穿山龙50、五加皮30、络石滕50。
上述治疗关节病的中药组合物的制备方法，包括以下步骤：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮40min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀，即得中药组合物。
实施例3
一种治疗关节骨病的中药组合物，包括以下重量组份(单位为g)：威灵仙45、红花55、川乌45、草乌55、甘草45、冰片55、骨碎补45、黄芩55、当归45、全蝎55、僵蚕45、丹参45、全虫45、干姜45、乳香35、三七45、透骨草25、海风藤35、独活25、川芎45、白芍35、荆芥45、穿山龙35、五加皮45、络石滕35。
包含上述治疗关节病的中药组合物的药酒的制备方法，包括以下步骤：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮30min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀。
(5)向将步骤(4)的混合液中加入白酒，密闭浸泡6个月后，过滤，获得药酒。
实施例4
一种治疗关节骨病的中药组合物，包括以下重量组份(单位为g)：威灵仙55、红花45、川乌55、草乌45、甘草55、冰片45、骨碎补55、黄芩45、当归55、全蝎45、僵蚕55、丹参35、全虫55、干姜35、乳香45、三七35、透骨草35、海风藤25、独活35、川芎35、白芍45、荆芥35、穿山龙45、五加皮35、络石滕45。
包含上述治疗关节病的中药组合物的药酒的制备方法，包括以下步骤：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮30min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀。
(5)向将步骤(4)的混合液中加入白酒，密闭浸泡6个月后，过滤，获得药酒。
实施例5
一种治疗关节骨病的中药组合物，包括以下重量组份(单位为g)：威灵仙50、红花50、川乌50、草乌50、甘草50、冰片50、骨碎补50、黄芩50、当归50、全蝎50、僵蚕50、丹参40、全虫50、干姜40、乳香40、三七40、透骨草30、海风藤30、独活30、川芎40、白芍40、荆芥40、穿山龙40、五加皮40、络石滕40。
上述治疗关节病的中药组合物的制备方法，包括以下步骤：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮20-40min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀，即得中药组合物。
以上述实施例5所制备的中药组合物进行药效判断，7天为一疗程，每日三次，每次100毫升。
选取80位志愿者进行药物治疗，志愿者治疗前症状如表1所示，治疗效果如表2所示：
表1：治疗前症状
表2：治疗后效果
典型病例：
1.张某，男，40岁，长期电脑前伏案工作，姿势不正确，造成严重颈椎疼痛，出现头晕现象，无法正常工作生活，服用本中药7天，疼痛感消失。
2.李某，女，55岁，长年体力劳动，造成严重腰椎疼痛，无法正常行走，服用本中药10天，疼痛感消失，恢复正常行走。
上述的志愿者中，病患症状较轻的关节骨病，例如颈椎、腰椎、膝盖、肩周等疼痛，一个疗程见效。症状较重的如压迫神经等，需要2-3个疗程。
实施例5的中药组合物配合外敷使用的药酒(实施例3或4)一起使用，效果更好，疗程也可缩短1-2天。
虽然本发明已以实施例公开如上，然其并非用于限定本发明，任何本领域技术人员，在不脱离本发明的精神和范围内，均可作各种不同的选择和修改，因此本发明的保护范围由权利要求书及其等同形式所限定。
Claims (7)
1.一种治疗关节病的中药组合物，其特征在于，包括以下重量份组份：威灵仙40-60、红花40-60、川乌40-60、草乌40-60、甘草40-60、冰片40-60、骨碎补40-60、黄芩40-60、当归40-60、全蝎40-60、僵蚕40-60、丹参30-50、全虫40-60、干姜30-50、乳香30-50、三七30-50、透骨草20-40、海风藤20-40、独活20-40、川芎30-50、白芍30-50、荆芥30-50、穿山龙30-50、五加皮30-50、络石滕30-50。
2.根据权利要求1所述的治疗关节病的中药组合物，其特征在于，包括以下重量份组份：威灵仙45-55、红花45-55、川乌45-55、草乌45-55、甘草45-55、冰片45-55、骨碎补45-55、黄芩45-55、当归45-55、全蝎45-55、僵蚕45-55、丹参35-45、全虫45-55、干姜35-45、乳香35-45、三七35-45、透骨草25-35、海风藤25-35、独活25-35、川芎35-45、白芍35-45、荆芥35-45、穿山龙35-45、五加皮35-45、络石滕35-45。
3.根据权利要求2所述的治疗关节病的中药组合物，其特征在于，包括以下重量份组份：威灵仙50、红花50、川乌50、草乌50、甘草50、冰片50、骨碎补50、黄芩50、当归50、全蝎50、僵蚕50、丹参40、全虫50、干姜40、乳香40、三七40、透骨草30、海风藤30、独活30、川芎40、白芍40、荆芥40、穿山龙40、五加皮40、络石滕40。
4.根据权利要求3所述的治疗关节病的中药组合物，其特征在于，还包括医学上可以接受的辅料。
5.根据权利要求1-4任一所述的治疗关节病的中药组合物的制备方法，其特征在于，包括以下步骤：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮20-40min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀，即得中药组合物。
6.一种药酒，其特征在于，该药酒包含权利要求1-4任一所述的中药组合物，所述药酒的制备方法如下：
(1)按量称取组合物中各组分，研磨粉碎；
(2)将川乌、冰片、荆芥、三七以外的各组分混合，浸泡2-3h后大火煎开，再改小火煎煮10-25min，得煎煮液；
(3)将川乌单独煎煮20-40min后，将其加入步骤(2)的煎煮液中混合；
(4)将冰片、荆芥、三七放入步骤(3)的混合液中混合均匀；
(5)向将步骤(4)的混合液中加入白酒，密闭浸泡6个月后，过滤，获得药酒。
7.根据权利要求1-4任一所述的中药组合物在制备用于治疗各种关节骨病药物或腰肌劳损症药物中的应用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111585518.2A CN116270948A (zh) | 2021-12-20 | 2021-12-20 | 一种治疗关节病的中药组合物及其制备方法和应用 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111585518.2A CN116270948A (zh) | 2021-12-20 | 2021-12-20 | 一种治疗关节病的中药组合物及其制备方法和应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116270948A true CN116270948A (zh) | 2023-06-23 |
Family
ID=86780179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111585518.2A Pending CN116270948A (zh) | 2021-12-20 | 2021-12-20 | 一种治疗关节病的中药组合物及其制备方法和应用 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116270948A (zh) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156048A (zh) * | 1996-11-22 | 1997-08-06 | 王义学 | 一种颈腰宁药物及其制备方法 |
| CN1181254A (zh) * | 1996-11-01 | 1998-05-13 | 戴光臻 | 一种风湿膏及其制备方法 |
| CN2794482Y (zh) * | 2005-02-18 | 2006-07-12 | 徐腾蛟 | 中药热敷治疗袋 |
| CN103211933A (zh) * | 2013-04-07 | 2013-07-24 | 柴八锋 | 一种治疗骨质增生的中药 |
| CN104116915A (zh) * | 2014-08-07 | 2014-10-29 | 上海中医药大学附属龙华医院 | 用于治疗骨关节退行性病变的中药 |
| CN106692942A (zh) * | 2017-03-31 | 2017-05-24 | 姜水胜 | 筋骨膏及其制备方法 |
-
2021
- 2021-12-20 CN CN202111585518.2A patent/CN116270948A/zh active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1181254A (zh) * | 1996-11-01 | 1998-05-13 | 戴光臻 | 一种风湿膏及其制备方法 |
| CN1156048A (zh) * | 1996-11-22 | 1997-08-06 | 王义学 | 一种颈腰宁药物及其制备方法 |
| CN2794482Y (zh) * | 2005-02-18 | 2006-07-12 | 徐腾蛟 | 中药热敷治疗袋 |
| CN103211933A (zh) * | 2013-04-07 | 2013-07-24 | 柴八锋 | 一种治疗骨质增生的中药 |
| CN104116915A (zh) * | 2014-08-07 | 2014-10-29 | 上海中医药大学附属龙华医院 | 用于治疗骨关节退行性病变的中药 |
| CN106692942A (zh) * | 2017-03-31 | 2017-05-24 | 姜水胜 | 筋骨膏及其制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110464826A (zh) | 一种中药泡脚药包 | |
| CN100512847C (zh) | 一种内服治疗颈椎病的中药组合物 | |
| CN105267389A (zh) | 一种用于活血消肿的外用药物 | |
| CN101019976B (zh) | 治疗骨关节病症的热敷药袋 | |
| CN102626505B (zh) | 基于中草药的按摩膏及其制备方法 | |
| CN102048900A (zh) | 用于治疗腰椎间盘突出症的中药制剂 | |
| CN103877517A (zh) | 一种治疗肺炎的中药 | |
| CN103623157A (zh) | 一种治疗面瘫的药物 | |
| CN103550345A (zh) | 一种治疗风湿疼痛的药酒 | |
| CN105832947A (zh) | 一种养生保健的泡脚中草药粉 | |
| CN107823280A (zh) | 一种治疗疼痛的中药组合物及其制备方法 | |
| CN103330798A (zh) | 一种治疗风湿病的中药制剂 | |
| CN112755169A (zh) | 一种治疗风湿骨痛的中药贴膏 | |
| CN116270948A (zh) | 一种治疗关节病的中药组合物及其制备方法和应用 | |
| CN105381399B (zh) | 追风祛湿骨刺胶囊 | |
| CN106421255B (zh) | 一种外用中草药组合物及其应用 | |
| CN105770251A (zh) | 一种治疗颈椎病、腰椎病和关节炎的通宁胶囊 | |
| CN105267703A (zh) | 一种治疗颈椎病中药 | |
| CN104645223A (zh) | 一种治疗坐骨神经痛的中药组合物 | |
| CN111265644A (zh) | 一种活骨止痛贴膏及其制备方法 | |
| CN109908245A (zh) | 一种用于治疗颈肩腰腿痛病的中药组合物 | |
| CN103736013B (zh) | 一种治疗肺结核的中药 | |
| CN111760008B (zh) | 一种外用骨质疏松药物及其制备方法 | |
| CN102847059A (zh) | 一组散瘀镇痛补肝肾药片 | |
| CN116270946A (zh) | 一种治疗关节疾病的膏药及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |