CN116249553A - 抗体-药物缀合物和抗体-皂苷缀合物的组合 - Google Patents
抗体-药物缀合物和抗体-皂苷缀合物的组合 Download PDFInfo
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- CN116249553A CN116249553A CN202180051961.3A CN202180051961A CN116249553A CN 116249553 A CN116249553 A CN 116249553A CN 202180051961 A CN202180051961 A CN 202180051961A CN 116249553 A CN116249553 A CN 116249553A
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2025905 | 2020-06-24 | ||
| NL2025905 | 2020-06-24 | ||
| PCT/NL2021/050391 WO2021261995A1 (en) | 2020-06-24 | 2021-06-22 | Combination of an antibody-drug conjugate and an antibody-saponin conjugate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
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| WO2023038517A1 (en) | 2021-09-09 | 2023-03-16 | Sapreme Technologies B.V. | Semicarbazone-based saponin conjugate |
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| US7256257B2 (en) * | 2001-04-30 | 2007-08-14 | Seattle Genetics, Inc. | Pentapeptide compounds and uses related thereto |
| EP1623715B1 (en) * | 2004-07-13 | 2012-09-19 | Charité - Universitätsmedizin Berlin | A composition comprising a pharmacologically active agent coupled to a target cell specific component, and a saponin |
| KR102256410B1 (ko) * | 2008-04-08 | 2021-05-26 | 슬로안-케테링인스티튜트퍼캔서리서치 | 트리테르펜 사포닌, 그의 합성 방법, 및 그의 용도 |
| JP6685924B2 (ja) * | 2014-04-11 | 2020-04-22 | メディミューン,エルエルシー | システイン操作抗体を含むコンジュゲート化合物 |
| SG11202106603UA (en) * | 2018-12-21 | 2021-07-29 | Sapreme Tech Bv | Biologically active cluster of molecules |
| ES3056941T3 (en) * | 2019-07-25 | 2026-02-25 | Sapreme Tech Bv | Saponin derivatives with improved therapeutic window |
| EP4003425A2 (en) * | 2019-07-25 | 2022-06-01 | Sapreme Technologies B.V. | Bioactive saponin linked to a functional moiety |
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| US20230248845A1 (en) | 2023-08-10 |
| WO2021261995A1 (en) | 2021-12-30 |
| AU2021297636A1 (en) | 2023-02-23 |
| EP4171642A1 (en) | 2023-05-03 |
| KR20230044195A (ko) | 2023-04-03 |
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| JP2023532679A (ja) | 2023-07-31 |
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Country or region after: Netherlands Address after: Utrecht Applicant after: Saprami Technology Co.,Ltd. Address before: Holland Bilthoven Applicant before: Saprami Technology Co.,Ltd. Country or region before: Netherlands |