CA3183883A1 - Combination of an antibody-drug conjugate and an antibody-saponin conjugate - Google Patents

Combination of an antibody-drug conjugate and an antibody-saponin conjugate

Info

Publication number
CA3183883A1
CA3183883A1 CA3183883A CA3183883A CA3183883A1 CA 3183883 A1 CA3183883 A1 CA 3183883A1 CA 3183883 A CA3183883 A CA 3183883A CA 3183883 A CA3183883 A CA 3183883A CA 3183883 A1 CA3183883 A1 CA 3183883A1
Authority
CA
Canada
Prior art keywords
binding
molecule
saponin
xyl
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3183883A
Other languages
English (en)
French (fr)
Inventor
Ruben POSTEL
Guy Hermans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sapreme Technologies BV
Original Assignee
Sapreme Technologies BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sapreme Technologies BV filed Critical Sapreme Technologies BV
Publication of CA3183883A1 publication Critical patent/CA3183883A1/en
Pending legal-status Critical Current

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Classifications

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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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US7256257B2 (en) * 2001-04-30 2007-08-14 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
EP1623715B1 (en) * 2004-07-13 2012-09-19 Charité - Universitätsmedizin Berlin A composition comprising a pharmacologically active agent coupled to a target cell specific component, and a saponin
KR102256410B1 (ko) * 2008-04-08 2021-05-26 슬로안-케테링인스티튜트퍼캔서리서치 트리테르펜 사포닌, 그의 합성 방법, 및 그의 용도
JP6685924B2 (ja) * 2014-04-11 2020-04-22 メディミューン，エルエルシー システイン操作抗体を含むコンジュゲート化合物
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ES3056941T3 (en) * 2019-07-25 2026-02-25 Sapreme Tech Bv Saponin derivatives with improved therapeutic window
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JP2023532679A (ja) 2023-07-31

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