CN116035570A - Stretchable physiological monitor attached to earlobe and method thereof - Google Patents
Stretchable physiological monitor attached to earlobe and method thereof Download PDFInfo
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- CN116035570A CN116035570A CN202210380107.8A CN202210380107A CN116035570A CN 116035570 A CN116035570 A CN 116035570A CN 202210380107 A CN202210380107 A CN 202210380107A CN 116035570 A CN116035570 A CN 116035570A
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- 210000000624 ear auricle Anatomy 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title claims description 7
- 239000008280 blood Substances 0.000 claims abstract description 27
- 210000004369 blood Anatomy 0.000 claims abstract description 27
- 238000012545 processing Methods 0.000 claims abstract description 19
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000001301 oxygen Substances 0.000 claims abstract description 12
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 12
- 239000000758 substrate Substances 0.000 claims description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 5
- 238000001514 detection method Methods 0.000 claims description 5
- 239000008103 glucose Substances 0.000 claims description 5
- 125000001931 aliphatic group Chemical group 0.000 claims description 4
- 229920013822 aminosilicone Polymers 0.000 claims description 4
- 125000003118 aryl group Chemical group 0.000 claims description 4
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 4
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 4
- 229920000058 polyacrylate Polymers 0.000 claims description 4
- -1 polydimethylsiloxane Polymers 0.000 claims description 4
- 229920000728 polyester Polymers 0.000 claims description 4
- 229910000530 Gallium indium arsenide Inorganic materials 0.000 claims description 3
- 239000005021 flexible packaging material Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 3
- 229920005604 random copolymer Polymers 0.000 claims description 3
- 238000013461 design Methods 0.000 abstract description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 208000024172 Cardiovascular disease Diseases 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
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- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 206010049418 Sudden Cardiac Death Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 230000008569 process Effects 0.000 description 1
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- 239000011347 resin Substances 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 208000014221 sudden cardiac arrest Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
- A61B5/1072—Measuring physical dimensions, e.g. size of the entire body or parts thereof measuring distances on the body, e.g. measuring length, height or thickness
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
- A61B5/1075—Measuring physical dimensions, e.g. size of the entire body or parts thereof for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
- A61B5/1079—Measuring physical dimensions, e.g. size of the entire body or parts thereof using optical or photographic means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6814—Head
- A61B5/6815—Ear
- A61B5/6816—Ear lobe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
- A61B2562/164—Details of sensor housings or probes; Details of structural supports for sensors the sensor is mounted in or on a conformable substrate or carrier
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- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
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Abstract
The invention relates to a stretchable physiological monitor attached to an earlobe, which comprises a light-emitting unit, a detector unit, a temperature sensor, a humidity sensor, a flexible circuit, a flexible functional shell, a power supply module, a control module and a signal processing module, wherein the light-emitting unit is connected with the detector unit; the light-emitting unit, the detector unit, the temperature sensor, the humidity sensor, the power module, the control module and the signal processing module are all arranged on the flexible circuit; the flexible circuit is encapsulated inside the flexible functional housing. The invention can rapidly and accurately measure important physiological information of the measured personnel, such as blood oxygen saturation, blood sugar concentration and the like, the extensible attaching design can enable the monitor to be in close contact with the skin, the accuracy and the precision are improved, the double-sided temperature and humidity design and the detector distribution can be optimally laid out, the signal interference is reduced, and the invention has wide market prospect in the fields of flexible electronics and wearable medical treatment.
Description
Technical Field
The invention relates to the field of physiological monitoring, in particular to a stretchable physiological monitor attached to an earlobe and a method thereof.
Background
In China, the death caused by cardiovascular diseases accounts for about 40% of the total death composition ratio, and the health of people is greatly threatened. Cardiovascular disease is characterized by sudden and dangerous, but studies indicate that 72% of patients have significant discomfort before sudden cardiac arrest occurs, with 70% of patients having symptoms lasting more than 15 minutes. Therefore, the real-time electrocardiographic monitoring of the patient and the timely discovery of the electrocardiographic abnormal change are of great significance for preventing and treating cardiovascular diseases. The traditional medical intelligent physiological monitor has the defect of inconvenient use.
Disclosure of Invention
Therefore, the invention aims to provide a stretchable physiological monitor attached to an earlobe and a method thereof, which can be carried conveniently and realize real-time physiological monitoring.
In order to achieve the above purpose, the invention adopts the following technical scheme:
a stretchable physiological monitor attached to an earlobe comprises a light-emitting unit, a detector unit, a temperature sensor, a humidity sensor, a flexible circuit, a flexible functional shell, a power supply module, a control module and a signal processing module; the light-emitting unit, the detector unit, the temperature sensor, the humidity sensor, the power module, the control module and the signal processing module are all arranged on the flexible circuit; the flexible circuit is encapsulated inside the flexible functional housing.
Further, the light emitting unit includes 5 lasers of different wavelengths, including green light for measuring the thickness of the earlobe, red light for measuring the blood oxygen concentration, infrared light for measuring the blood glucose concentration, and two near infrared light.
Further, the detector unit includes two InGaAs detectors, one for receiving reflected signals of red light and near infrared light and one for receiving transmitted signals of green light, near infrared light and infrared light.
Further, the flexible functional shell comprises a flexible shading layer, a stretchable substrate and a flexible package which are sequentially arranged; two magnets are symmetrically arranged between the stretchable substrates; the two magnets are adsorbed together after the stretchable physiological monitor is bent.
Further, the temperature sensor comprises two units which are respectively arranged at two sides of the stretchable physiological monitor after being bent.
Further, the humidity sensor comprises two units which are respectively arranged at two sides of the stretchable physiological monitor after being bent.
Further, the control module is respectively connected with the control light-emitting unit, the detection unit, the temperature sensor, the humidity sensor, the power module and the signal processing module, and obtains and controls the data of each unit.
Further, the stretchable substrate material and the flexible packaging material adopt one or more of polydimethylsiloxane, aliphatic or aromatic random copolymerized polyester, polyacrylate, polymethyl silicone resin, amino silicone resin or fluorine silicone resin.
Furthermore, the 5 lasers of the light-emitting unit are all positioned on the front surface of the earlobe and are divided into three groups of red light, near infrared light, infrared light and green light, and the 5 wavelengths are not mutually intersected.
A control method of a stretchable physiological monitor fitting an earlobe, comprising the steps of:
step S1, properly stretching the stretchable physiological monitor, and respectively placing two magnets on the opposite front and back sides of the earlobe to loosen the two magnets, so as to fix the stretchable physiological monitor on the earlobe;
s2, converting the electric signals of the temperature sensor and the humidity sensor into temperature and humidity information by the signal processing module, analyzing the influence of temperature and humidity fluctuation on signal processing, converting the electric signals of the front detector into blood oxygen saturation signals, converting the electric signals of the back detector into earlobe thickness signals and partial blood sugar information, and calculating the blood sugar concentration value of the measured person according to the earlobe thickness, the blood oxygen saturation and the partial blood sugar information of the measured person;
and step S3, the acquired detection data are sent to the mobile terminal.
Compared with the prior art, the invention has the following beneficial effects:
the invention can rapidly and accurately measure important physiological information of the measured personnel, such as blood oxygen saturation, blood sugar concentration and the like, the extensible attaching design can enable the monitor to be in close contact with the skin, the accuracy and the precision are improved, the double-sided temperature and humidity design and the detector distribution can be optimally laid out, the signal interference is reduced, and the invention has wide market prospect in the fields of flexible electronics and wearable medical treatment.
Drawings
FIG. 1 is a schematic diagram of an apparatus according to an embodiment of the present invention;
FIG. 2 is a schematic view of a folded device according to an embodiment of the present invention;
FIG. 3 is a schematic diagram of a detection method according to an embodiment of the invention;
the device comprises a 1-luminous unit, a 2-detector unit, a 3-temperature sensor, a 4-humidity sensor, a 5-flexible circuit, a 6-flexible functional housing, a 7-power module, an 8-control module and a 9-signal processing module.
Detailed Description
The invention will be further described with reference to the accompanying drawings and examples.
Referring to fig. 1, the present invention provides a stretchable physiological monitor fitting an earlobe, comprising: the device comprises a light emitting unit, a detector unit, a temperature sensor, a humidity sensor, a flexible circuit, a flexible functional shell, a power module, a control module and a signal processing module.
In this embodiment, the light emitting unit includes 5 lasers with different wavelengths, which are respectively green light, red light, infrared light, and two near infrared lights, and the 5 wavelengths do not intersect with each other; green light is used to measure earlobe thickness, red light and one near infrared light are used to measure blood oxygen concentration, and the other near infrared light and infrared light are used to measure blood glucose concentration.
In this embodiment, the detector unit includes two InGaAs detectors, and 2 detectors are respectively located on the front and back sides of the earlobe, where the front detector is configured to receive reflected signals of red light and near infrared light, and the response band includes at least red light and near infrared light; the detector on the back side is used for receiving transmission signals of green light, near infrared light and infrared light. The reflected signals received by the front detector contain blood oxygen information, and the blood oxygen signals are converted into electric signals and fed back to the signal processing module. The transmission signal received by the detector on the back contains the thickness of the earlobe (green light signal) and partial blood sugar information (near infrared light and infrared light), and the thickness and blood sugar signals are converted into electric signals and fed back to the signal processing module.
In this embodiment, 2 sensors of the temperature sensor are respectively located on the front and back of the earlobe, so that temperatures near the light emitting unit and the detector unit can be monitored, and temperature information is converted into voltage signals and fed back to the signal processing module.
In this embodiment, 2 sensors of the humidity sensor are respectively located on the front and back of the earlobe, and are used for monitoring the humidity near the light emitting unit and the detector unit, converting the humidity information into a voltage signal, and feeding the voltage signal back to the signal processing module.
In this embodiment, the flexible circuit is a polymer/electrode/polymer sandwich structure, and the polymer provides protection and support for the electrode and may be one of polydimethylsiloxane, aliphatic or aromatic random copolymer polyester, polyacrylate, polymethyl silicone, amino silicone or fluorosilicone; the shape of the electrode is one of a first-order or second-order self-similar snake shape, a saddle shape, a semicircle shape and an ellipse shape.
In this embodiment, the flexible functional housing of the stretchable physiological monitor may be stretched and bent, and the stretchable substrate material and the flexible packaging material may be one or more of polydimethylsiloxane, aliphatic or aromatic random copolymer polyester, polyacrylate, polymethyl silicone, amino silicone or fluorosilicone; the flexible shading layer is black, so that the influence of ambient light on the performance of the monitor is prevented; the two magnets are positioned between the stretchable substrate and the light shielding layer, and the two magnets are arranged to be attracted together when being opposite to each other.
In this embodiment, the signal processing module is configured to process the measured electrical signal to obtain a blood oxygen saturation level, a blood glucose concentration, and a temperature and humidity value, and transmit the signal to other terminals.
The foregoing description is only of the preferred embodiments of the invention, and all changes and modifications that come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Claims (10)
1. The stretchable physiological monitor is characterized by comprising a light-emitting unit, a detector unit, a temperature sensor, a humidity sensor, a flexible circuit, a flexible functional shell, a power module, a control module and a signal processing module; the light-emitting unit, the detector unit, the temperature sensor, the humidity sensor, the power module, the control module and the signal processing module are all arranged on the flexible circuit; the flexible circuit is encapsulated inside the flexible functional housing.
2. The stretchable physiological monitor according to claim 1, wherein said light emitting unit comprises 5 lasers of different wavelengths, including green light for measuring the thickness of the earlobe, red light for measuring blood oxygen concentration, infrared light for measuring blood glucose concentration, and two near infrared light for measuring blood glucose concentration.
3. The conformable earlobe stretchable physiological monitor of claim 1 wherein the detector unit comprises two InGaAs detectors, one for receiving red and near infrared reflected signals and one for receiving green, near infrared and infrared transmitted signals.
4. The stretchable physiological monitor fitting an earlobe of claim 1, wherein the flexible functional housing comprises a flexible light shielding layer, a stretchable substrate and a flexible package arranged in sequence; two magnets are symmetrically arranged between the stretchable substrates; the two magnets are adsorbed together after the stretchable physiological monitor is bent.
5. The stretchable physiological monitor according to claim 4, wherein the temperature sensor comprises two units respectively disposed on two sides of the stretchable physiological monitor after being bent.
6. The stretchable physiological monitor according to claim 4, wherein the humidity sensor comprises two units respectively disposed on two sides of the stretchable physiological monitor after being bent.
7. The stretchable physiological monitor according to claim 1, wherein the control module is connected to the control lighting unit, the detection unit, the temperature sensor, the humidity sensor, the power module and the signal processing module, respectively, and obtains and controls data of each unit.
8. The stretchable physiological monitor according to claim 4, wherein the stretchable backing material and the flexible packaging material are one or more of polydimethylsiloxane, aliphatic or aromatic random copolymer polyester, polyacrylate, polymethyl silicone, amino silicone, and fluorosilicone.
9. The stretchable physiological monitor according to claim 1, wherein the 5 lasers of the light emitting unit are all located on the front surface of the earlobe, and are divided into three groups of red light, near infrared light, infrared light and green light, and the 5 wavelengths do not intersect each other.
10. A control method of a stretchable physiological monitor attached to an earlobe, comprising the steps of:
step S1, properly stretching the stretchable physiological monitor, and respectively placing two magnets on the opposite front and back sides of the earlobe to loosen the two magnets, so as to fix the stretchable physiological monitor on the earlobe;
s2, converting the electric signals of the temperature sensor and the humidity sensor into temperature and humidity information by the signal processing module, analyzing the influence of temperature and humidity fluctuation on signal processing, converting the electric signals of the front detector into blood oxygen saturation signals, converting the electric signals of the back detector into earlobe thickness signals and partial blood sugar information, and calculating the blood sugar concentration value of the measured person according to the earlobe thickness, the blood oxygen saturation and the partial blood sugar information of the measured person;
and step S3, the acquired detection data are sent to the mobile terminal.
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CN202210380107.8A CN116035570A (en) | 2022-04-12 | 2022-04-12 | Stretchable physiological monitor attached to earlobe and method thereof |
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CN202210380107.8A CN116035570A (en) | 2022-04-12 | 2022-04-12 | Stretchable physiological monitor attached to earlobe and method thereof |
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CN210044008U (en) * | 2019-02-22 | 2020-02-11 | 孙雁 | Blood sugar detector for children |
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CN111789600A (en) * | 2020-07-13 | 2020-10-20 | 闽江学院 | Structure of ultra-thin and ultra-sensitive blood oxygen monitor |
CN217987573U (en) * | 2022-04-12 | 2022-12-09 | 闽江学院 | Stretchable physiological monitor attached to earlobe |
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2022
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US5974337A (en) * | 1995-05-23 | 1999-10-26 | Kaffka; Karoly | Method and apparatus for rapid non-invasive determination of blood composition parameters |
JPH09215679A (en) * | 1996-02-09 | 1997-08-19 | Matsushita Electric Works Ltd | Concentration measuring apparatus for humor component |
CN1600271A (en) * | 2003-09-24 | 2005-03-30 | 株式会社日立制作所 | Optical measurement apparatus and blood sugar level measuring apparatus using the same |
CN205054226U (en) * | 2015-10-13 | 2016-03-02 | 黄世通 | Blood glucose monitoring analytical equipment |
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CN217987573U (en) * | 2022-04-12 | 2022-12-09 | 闽江学院 | Stretchable physiological monitor attached to earlobe |
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