CN111789600A - Structure of ultra-thin and ultra-sensitive blood oxygen monitor - Google Patents
Structure of ultra-thin and ultra-sensitive blood oxygen monitor Download PDFInfo
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
Abstract
The invention provides a structure of an ultrathin and ultrasensitive blood oxygen monitor, wherein the monitoring structure of the monitor is a flexible packaging sheet body; the middle part of the monitoring surface of the flexible packaging sheet body is a soft luminous piece; soft photoelectric detection pieces are arranged around the light-emitting piece in a surrounding manner; the invention has novel structure, the structural design that the detection area surrounds the light emitting area can reduce the optical loss, reduce the power consumption of a light emitting device and improve the sensitivity of the detector, and meanwhile, the OLED and the two-dimensional photoelectric detector are combined, the thickness of the whole device can be greatly reduced, the whole thickness of the device is less than micrometer, the device can be tightly attached to the skin of a human body, and the carrying and the use are convenient.
Description
Technical Field
The invention relates to the technical field of monitoring instruments, in particular to a structure of an ultrathin and ultrasensitive blood oxygen monitor.
Background
The World Health Organization (WHO) emphasizes the medical science of the 21 st century in the 21 st century challenge report, should not continue to focus on diseases as the main field, should focus on human health as the main direction of development of medical science. "Chronic non-infectious disease has become a major threat to human health and illness, and is the global medical crisis facing the current society, e.g., approximately 1790 million people die of cardiovascular-related diseases each year, accounting for 31% of the total number of deaths worldwide. In order to control the development of non-inductive chronic diseases, the medical mode is gradually changed from diagnosis to prevention, from hospitalization to daily prevention and health monitoring, and the physiological information of a human body is dynamically monitored in real time through organic integration of devices and the human body. However, human body and tissue thereof are mostly non-developable surfaces, and the traditional photoelectric device based on semiconductor material cannot be tightly attached to the human body due to the rigid characteristic thereof, and a breakthrough is needed in key problems of convenience, continuous monitoring and the like.
The flexible inorganic electronic device integrates the inorganic functional unit on the flexible substrate, and fully utilizes the high performance of the semiconductor device and the flexibility of the organic material, so that the flexible inorganic electronic device has extensible flexibility, conformal bonding and biocompatibility. Due to the advantages of the flexible inorganic electronic device in the aspects of human body signal acquisition, management, utilization and the like, the flexible inorganic electronic device is widely applied to the field of health monitoring, and a large number of prototype devices are also emerged. However, due to the existence of the inorganic functional unit, the thickness and flexibility of the whole device are limited, which greatly affects the experience and comfort of users. Meanwhile, the semiconductor processing equipment is expensive, the process is complex, the preparation time is long, and the commercial development is not facilitated.
The main product on the market at present is a clip type pulse oximeter, which has a large volume and very high requirement on the stability of a monitored object, and meanwhile, a plurality of flexible inorganic blood oxygen detectors reported in literatures can be attached to a human body to measure blood oxygen. However, these devices all use a single or several micro-detectors, and can only receive reflected light in a single direction, and most of the light emitted by the LED is lost after being reflected by the blood tissue of the human body and is not detected by the detector. This will undoubtedly reduce the sensitivity of the device, while also not contributing to reducing the power consumption of the LED. How to improve the structural design of the blood oxygen detector and improve the flexibility and the sensitivity of the device is a problem which needs to be solved urgently.
Disclosure of Invention
The invention provides a structure of an ultrathin and ultrasensitive blood oxygen monitor, which is novel in structure, the structural design that a detection area surrounds a light emitting area can reduce light loss, reduce the power consumption of a light emitting device and improve the sensitivity of a detector, meanwhile, the OLED and a two-dimensional photoelectric detector are combined, the thickness of the whole device can be greatly reduced, the whole thickness of the device is less than microns, the device can be tightly attached to human skin, and the carrying and the use are convenient.
The invention adopts the following technical scheme.
The structure of the ultra-thin and ultra-sensitive blood oxygen monitor is characterized in that the monitoring structure of the monitor is a flexible packaging sheet body; the middle part of the monitoring surface of the flexible packaging sheet body is a soft luminous piece; and soft photoelectric detection pieces are arranged around the light-emitting piece in a surrounding manner.
The light emitting piece comprises a red light OLED light emitting piece and an infrared light OLED light emitting piece; the red light OLED light-emitting piece and the infrared light OLED light-emitting piece are arranged side by side or stacked in the middle of the monitoring surface of the flexible packaging sheet body; the non-monitoring surface of the flexible packaging sheet body is covered with a soft shading layer.
The soft photoelectric detection piece is an annular graphene photoelectric detector.
The flexible packaging sheet body forms a packaging structure by PDMS packaging material; the shading layer is formed by a black adhesive tape, and the red OLED light emitting part and the infrared OLED light emitting part are OLED devices of a multilayer structure.
The thickness of the flexible packaging sheet body is less than 1 micron; the area of the illuminating part in the top view direction is less than 1mm2The whole area of the oximeter is less than 1cm2The thickness is between 50nm and 1000 nm;
the red OLED light-emitting component can emit red light with the wavelength of 500-700 nm; the infrared OLED light-emitting piece can emit infrared light with the wavelength of 700-1000 nm.
When the monitor monitors the blood oxygen of a person to be monitored, the monitoring surface is tightly attached to the surface of a human body, the graphene photoelectric detector is connected with an external analysis module, and the red light OLED light-emitting piece and the infrared light OLED light-emitting piece alternately emit detection light to human tissues according to a preset frequency; after the alternately emitted detection light is reflected by human tissues, a monitoring signal which can be received by the graphene photoelectric detector surrounding the reflection area is formed; after the monitoring signal is analyzed by the external analysis module, the blood oxygen saturation and the pulse parameters of the person to be detected can be obtained.
The preparation method of the monitoring structure comprises the following steps;
step A1, sequentially spin-coating a hole transport layer PEDOT, namely PSS, a red light emitting layer DCJTB or an infrared light emitting layer NZ2TPA and an electron transport layer Alq3 on the ITO film in sequence, and then sputtering a layer of cathode Ca/Al with the thickness of 50nm to form a patterned light emitting region to be used as a light emitting element;
step A2, preparing a ring-shaped graphene detection material at the periphery of a luminous zone by a transfer printing method, and sputtering a layer of gold electrode on the inner side and the outer side of a ring to form a ring-shaped detection zone which is used as a soft photoelectric detection piece;
a3, adhering a black adhesive tape on the back of the ITO film to form a shading layer;
and A4, spin-coating a layer of PDMS solution on the front surface, and curing at 80 ℃ for 2 hours to complete flexible packaging.
The anode or the cathode of the luminous region is prepared by a magnetron sputtering or evaporation method; the electron/hole transport layer, the light emitting layer and the electron/hole injection layer in the light emitting region are prepared by a spin coating method, wherein the light emitting layer is made of one or more of rhodamine dyes, DCM, DCT, DCJT, DCJTB, DCJTI, TPBD, Alq3 and derivatives thereof, poly (p-phenylene vinylene) (PPV) and derivatives thereof, Polythiophene (PT) and derivatives thereof, and poly (PPP) and derivatives thereof.
The annular graphene photoelectric detector is a two-dimensional photoelectric detector, a detection material is arranged in the middle of the annular structure, the detection material is two-dimensional materials such as graphene, carbon nano tubes, black phosphorus, molybdenum disulfide and the like or a mixed material thereof, and metal material electrodes or alloy material electrodes are arranged on two sides of the annular structure, wherein the metal material can be gold, silver, platinum, palladium, aluminum, nickel, copper, titanium, chromium, tin, iron, manganese, molybdenum, tungsten or vanadium; the alloy material can be selected from aluminum alloy, titanium alloy, magnesium alloy, beryllium alloy, copper alloy, zinc alloy, manganese alloy, nickel alloy, lead alloy, tin alloy, cadmium alloy, bismuth alloy, indium alloy, gallium alloy, tungsten alloy, molybdenum alloy, niobium alloy or tantalum alloy;
the detection material in the middle of the annular structure is prepared by a transfer printing method, and the electrodes on two sides of the annular structure are prepared by a magnetron sputtering or evaporation method.
Transparent flexible protective layers are coated on the monitoring surface, which are positioned on the light-emitting part and the photoelectric detection part, and the flexible protective layers can be made of polydimethylsiloxane, aliphatic or aromatic random copolymer polyester, polyacrylate, polymethyl silicone resin, amino silicone resin or fluorine silicone resin; the light shielding layer material of the non-monitoring surface can be black light shielding adhesive tape or black aluminum foil.
The whole monitor is novel in structure, the light loss can be reduced due to the structural design that the detection area surrounds the light emitting area, the power consumption of a light emitting device is reduced, the sensitivity of the detector is improved, meanwhile, the thickness of the whole device can be greatly reduced due to the combination of the OLED and the two-dimensional photoelectric detector, the whole thickness of the device is smaller than microns, the device can be tightly attached to the skin of a human body, the carrying and the use are convenient, and the monitor has the following advantages.
(1) The characteristics of ultra-thin and ultra-light are as follows: the device has millimeter-sized and micron-sized thickness, and the human body can hardly feel the existence of the device.
(2) Possesses super high monitoring sensitivity: the device adopts the structural design that the detector surrounds the luminous zone, most of the emitted light is detected by the detector after being reflected by blood tissues, and the sensitivity of the device is improved.
(3) Ultra-low operating power consumption: because the device can be tightly attached to a human body when in work, the luminous power of the OLED does not need to be high, a better reflected light signal can be obtained, and the detector is arranged around the luminous zone, so that the power consumption of the device in work is further reduced.
Drawings
The invention is described in further detail below with reference to the following figures and detailed description:
FIG. 1 is a schematic illustration of a monitoring surface of the present invention;
FIG. 2 is a schematic structural view of the present invention;
FIG. 3 is a schematic view of a glowing member of the present invention;
FIG. 4 is a schematic representation of the use of the present invention;
in the figure: 1-a light emitting member; 2-a photoelectric detector; 3-packaging the structure; 4-red OLED lighting; 5-infrared light OLED light emitting piece; 6-a light shielding layer; 7-monitoring surface; 8-non-monitoring surface; 9-human tissue.
Detailed Description
As shown in fig. 1-4, a structure of an ultra-thin and ultra-sensitive blood oxygen monitor, the monitoring structure of the monitor is a flexible packaging sheet; the middle part of the monitoring surface 7 of the flexible packaging sheet body is a soft luminous element 1; the periphery of the light-emitting piece is provided with a soft photoelectric detection piece 2 in a surrounding way.
The light emitting members comprise a red OLED light emitting member 4 and an infrared OLED light emitting member 5; the red light OLED light-emitting piece and the infrared light OLED light-emitting piece are arranged side by side or stacked in the middle of the monitoring surface of the flexible packaging sheet body; and the non-monitoring surface 8 of the flexible packaging sheet body is covered with a soft shading layer 6.
The soft photoelectric detection piece is an annular graphene photoelectric detector.
The flexible packaging sheet body forms a packaging structure 3 by PDMS packaging material; the shading layer is formed by a black adhesive tape, and the red OLED light emitting part and the infrared OLED light emitting part are OLED devices of a multilayer structure.
The thickness of the flexible packaging sheet body is less than 1 micron; the area of the illuminating part in the top view direction is less than 1mm2The whole area of the oximeter is less than 1cm2The thickness is between 50nm and 1000 nm;
the red OLED light-emitting component can emit red light with the wavelength of 500-700 nm; the infrared OLED light-emitting piece can emit infrared light with the wavelength of 700-1000 nm.
When the monitor monitors the blood oxygen of a person to be monitored, the monitoring surface is tightly attached to the surface of a human body, the graphene photoelectric detector is connected with an external analysis module, and the red light OLED light-emitting piece and the infrared light OLED light-emitting piece alternately emit detection light to human tissues 9 according to a preset frequency; after the alternately emitted detection light is reflected by human tissues, a monitoring signal which can be received by the graphene photoelectric detector surrounding the reflection area is formed; after the monitoring signal is analyzed by the external analysis module, the blood oxygen saturation and the pulse parameters of the person to be detected can be obtained.
The preparation method of the monitoring structure comprises the following steps;
step A1, sequentially spin-coating a hole transport layer PEDOT, namely PSS, a red light emitting layer DCJTB or an infrared light emitting layer NZ2TPA and an electron transport layer Alq3 on the ITO film in sequence, and then sputtering a layer of cathode Ca/Al with the thickness of 50nm to form a patterned light emitting region to be used as a light emitting element;
step A2, preparing a ring-shaped graphene detection material at the periphery of a luminous zone by a transfer printing method, and sputtering a layer of gold electrode on the inner side and the outer side of a ring to form a ring-shaped detection zone which is used as a soft photoelectric detection piece;
a3, adhering a black adhesive tape on the back of the ITO film to form a shading layer;
and A4, spin-coating a layer of PDMS solution on the front surface, and curing at 80 ℃ for 2 hours to complete flexible packaging.
The anode or the cathode of the luminous region is prepared by a magnetron sputtering or evaporation method; the electron/hole transport layer, the light emitting layer and the electron/hole injection layer in the light emitting region are prepared by a spin coating method, wherein the light emitting layer is made of one or more of rhodamine dyes, DCM, DCT, DCJT, DCJTB, DCJTI, TPBD, Alq3 and derivatives thereof, poly (p-phenylene vinylene) (PPV) and derivatives thereof, Polythiophene (PT) and derivatives thereof, and poly (PPP) and derivatives thereof.
The annular graphene photoelectric detector is a two-dimensional photoelectric detector, a detection material is arranged in the middle of the annular structure, the detection material is two-dimensional materials such as graphene, carbon nano tubes, black phosphorus, molybdenum disulfide and the like or a mixed material thereof, and metal material electrodes or alloy material electrodes are arranged on two sides of the annular structure, wherein the metal material can be gold, silver, platinum, palladium, aluminum, nickel, copper, titanium, chromium, tin, iron, manganese, molybdenum, tungsten or vanadium; the alloy material can be selected from aluminum alloy, titanium alloy, magnesium alloy, beryllium alloy, copper alloy, zinc alloy, manganese alloy, nickel alloy, lead alloy, tin alloy, cadmium alloy, bismuth alloy, indium alloy, gallium alloy, tungsten alloy, molybdenum alloy, niobium alloy or tantalum alloy;
the detection material in the middle of the annular structure is prepared by a transfer printing method, and the electrodes on two sides of the annular structure are prepared by a magnetron sputtering or evaporation method.
Transparent flexible protective layers are coated on the monitoring surface, which are positioned on the light-emitting part and the photoelectric detection part, and the flexible protective layers can be made of polydimethylsiloxane, aliphatic or aromatic random copolymer polyester, polyacrylate, polymethyl silicone resin, amino silicone resin or fluorine silicone resin; the light shielding layer material of the non-monitoring surface can be black light shielding adhesive tape or black aluminum foil.
The light-emitting piece is in a circular, square, triangular or other polygonal structure in the overlooking direction, and a space is arranged between the light-emitting piece and the annular graphene photoelectric detector.
Example (b):
the middle circular area of the monitoring surface is a light emitting area with the diameter of 1mm, the left part of the light emitting area is a red light OLED, and the right part of the light emitting area is an infrared light OLED.
A circle of ring is graphite alkene photoelectric detector around sending out the district, and the external diameter is 8mm, and the internal diameter is 1mm, adopts PDMS packaging material, and the light shield layer is black sticky tape, and the whole thickness of device is 500 nm.
When the device works, in a period of time (about 3 s), the red light OLED emits light, the emitted light enters blood tissues of a human body, is received by the graphene photoelectric detectors in all directions after being reflected, then the infrared light OLED emits light within 3s, the emitted light is also received by the detector after being reflected, the two red light/infrared light alternately emit light, light signals received by the detector comprise blood oxygen and pulse information, and the blood oxygen saturation and pulse parameters can be obtained through analysis processing.
It should be noted that in the drawings or description, the same drawing reference numerals are used for similar or identical parts. Implementations not depicted or described in the drawings are of a form known to those of ordinary skill in the art. Additionally, while exemplifications of parameters including particular values may be provided herein, it is to be understood that the parameters need not be exactly equal to the respective values, but may be approximated to the respective values within acceptable error margins or design constraints. Directional phrases used in the embodiments, such as "upper", "lower", "front", "rear", "left", "right", etc., refer only to the direction of the attached drawings and are not intended to limit the scope of the present invention.
The above-mentioned embodiments are intended to illustrate the objects, technical solutions and advantages of the present invention in further detail, and it should be understood that the above-mentioned embodiments are only exemplary embodiments of the present invention and are not intended to limit the present invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. The utility model provides a structure of ultra-thin ultrasensitive blood oxygen monitor which characterized in that: the monitoring structure of the monitor is a flexible packaging sheet body; the middle part of the monitoring surface of the flexible packaging sheet body is a soft luminous piece; and soft photoelectric detection pieces are arranged around the light-emitting piece in a surrounding manner.
2. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 1, wherein: the light emitting piece comprises a red light OLED light emitting piece and an infrared light OLED light emitting piece; the red light OLED light-emitting piece and the infrared light OLED light-emitting piece are arranged side by side or stacked in the middle of the monitoring surface of the flexible packaging sheet body; the non-monitoring surface of the flexible packaging sheet body is covered with a soft shading layer.
3. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 2, wherein: the soft photoelectric detection piece is an annular graphene photoelectric detector.
4. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 3, wherein: the flexible packaging sheet body forms a packaging structure by PDMS packaging material; the shading layer is formed by a black adhesive tape, and the red OLED light emitting part and the infrared OLED light emitting part are OLED devices of a multilayer structure.
5. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 3, wherein: the thickness of the flexible packaging sheet body is less than 1 micron; the area of the illuminating part in the top view direction is less than 1mm2The whole area of the oximeter is less than 1cm2The thickness is between 50nm and 1000 nm;
the red OLED light-emitting component can emit red light with the wavelength of 500-700 nm; the infrared OLED light-emitting piece can emit infrared light with the wavelength of 700-1000 nm.
6. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 3, wherein: when the monitor monitors the blood oxygen of a person to be monitored, the monitoring surface is tightly attached to the surface of a human body, the graphene photoelectric detector is connected with an external analysis module, and the red light OLED light-emitting piece and the infrared light OLED light-emitting piece alternately emit detection light to human tissues according to a preset frequency; after the alternately emitted detection light is reflected by human tissues, a monitoring signal which can be received by the graphene photoelectric detector surrounding the reflection area is formed; after the monitoring signal is analyzed by the external analysis module, the blood oxygen saturation and the pulse parameters of the person to be detected can be obtained.
7. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 4, wherein: the preparation method of the monitoring structure comprises the following steps;
step A1, sequentially spin-coating a hole transport layer PEDOT, namely PSS, a red light emitting layer DCJTB or an infrared light emitting layer NZ2TPA and an electron transport layer Alq3 on the ITO film in sequence, and then sputtering a layer of cathode Ca/Al with the thickness of 50nm to form a patterned light emitting region to be used as a light emitting element;
step A2, preparing a ring-shaped graphene detection material at the periphery of a luminous zone by a transfer printing method, and sputtering a layer of gold electrode on the inner side and the outer side of a ring to form a ring-shaped detection zone which is used as a soft photoelectric detection piece;
a3, adhering a black adhesive tape on the back of the ITO film to form a shading layer;
and A4, spin-coating a layer of PDMS solution on the front surface, and curing at 80 ℃ for 2 hours to complete flexible packaging.
8. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 3, wherein: the anode or the cathode of the luminous region is prepared by a magnetron sputtering or evaporation method; the electron/hole transport layer, the light emitting layer and the electron/hole injection layer in the light emitting region are prepared by a spin coating method, wherein the light emitting layer is made of one or more of rhodamine dyes, DCM, DCT, DCJT, DCJTB, DCJTI, TPBD, Alq3 and derivatives thereof, poly (p-phenylene vinylene) (PPV) and derivatives thereof, Polythiophene (PT) and derivatives thereof, and poly (PPP) and derivatives thereof.
9. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 3, wherein: the annular graphene photoelectric detector is a two-dimensional photoelectric detector, a detection material is arranged in the middle of the annular structure, the detection material is two-dimensional materials such as graphene, carbon nano tubes, black phosphorus, molybdenum disulfide and the like or a mixed material thereof, and metal material electrodes or alloy material electrodes are arranged on two sides of the annular structure, wherein the metal material can be gold, silver, platinum, palladium, aluminum, nickel, copper, titanium, chromium, tin, iron, manganese, molybdenum, tungsten or vanadium; the alloy material can be selected from aluminum alloy, titanium alloy, magnesium alloy, beryllium alloy, copper alloy, zinc alloy, manganese alloy, nickel alloy, lead alloy, tin alloy, cadmium alloy, bismuth alloy, indium alloy, gallium alloy, tungsten alloy, molybdenum alloy, niobium alloy or tantalum alloy;
the detection material in the middle of the annular structure is prepared by a transfer printing method, and the electrodes on two sides of the annular structure are prepared by a magnetron sputtering or evaporation method.
10. The ultra-thin ultra-sensitive blood oxygen monitor structure according to claim 3, wherein: transparent flexible protective layers are coated on the monitoring surface, which are positioned on the light-emitting part and the photoelectric detection part, and the flexible protective layers can be made of polydimethylsiloxane, aliphatic or aromatic random copolymer polyester, polyacrylate, polymethyl silicone resin, amino silicone resin or fluorine silicone resin; the light shielding layer material of the non-monitoring surface can be black light shielding adhesive tape or black aluminum foil.
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