WO2020130571A1

WO2020130571A1 - Non-invasive blood testing device and method

Info

Publication number: WO2020130571A1
Application number: PCT/KR2019/017876
Authority: WO
Inventors: 이성철; 한철구; 박원기; 김경국; 권순환; 노범래; 이원석; 임광균; 최희정
Original assignee: 전자부품연구원
Priority date: 2018-12-19
Filing date: 2019-12-17
Publication date: 2020-06-25

Abstract

According to a non-invasive blood testing apparatus of the present invention, a blood testing method in the non-invasive blood testing apparatus of the present invention supports a dual mode such that selection of any one test mode between a transmittance test mode and a reflectance test mode is possible in accordance with the composition of the blood.

Description

Non-invasive blood test apparatus and method

The present invention relates to a technique for inspecting minute components such as blood sugar, urea and cholesterol in blood in a non-invasive manner using light.

Currently, a representative method for testing components such as blood sugar in blood is an invasive method in which a blood sample is extracted and measured using a dedicated tester. Unlike this invasive method, a non-invasive blood test technique for solving psychological stability, test duration, and discomfort of patients who need to check blood conditions such as blood sugar at all times is currently being actively researched.

Among non-invasive blood test techniques, there is a non-invasive technique using light.

As a non-invasive blood tester, a detection method using an infrared light source is known. In this detection method, when the infrared wavelength that reacts with Glucose in the blood is irradiated to the blood, the blood state is detected by comparing the intensity of the transmitted infrared rays with normal human blood and diabetic blood. In this method, it is implemented as an optical module (hereinafter referred to as an optical non-invasive blood test apparatus) using a single photodiode element and a plurality of LED elements.

The optical non-invasive blood test apparatus can be largely classified into a reflective type and a transmissive type according to its operating principle.

The reflective optical non-invasive blood test device has a disadvantage in that it is very difficult to set a reference point for a measured value due to different light reflection characteristics according to an individual's skin condition (color, thickness, etc.).

The transmissive optical non-invasive blood test apparatus has a drawback that it is difficult to secure its precision due to various optical attenuation and noise sources existing inside the human body such as subcutaneous fat.

For this reason, currently, non-invasive blood test products using light have a disadvantage that it is difficult to apply to other components such as blood sugar and urea except simple tests such as oxygen saturation or pulse.

To overcome these drawbacks, a high-precision optical blood test apparatus using a continuous light source such as a halogen lamp has been recently developed. However, this inspection device requires expensive parts such as a spectrum analyzer, and since the size of the measurement device is large, it is limited to be utilized by an individual or implemented as a wearable device.

The present invention is to solve the above-mentioned problems and can be implemented at a small size and low cost for use as a wearable device, and to provide a non-invasive blood test apparatus and method for reducing errors in measurement values. There is this.

The above-mentioned objects and other objects, advantages and features of the present invention, and methods for achieving them will be clarified through the embodiments described below in detail with reference to the accompanying drawings.

In the blood test method of the non-invasive blood test apparatus of the present invention, among the first and second optical modules facing each other with a specific body part therebetween, the first LED element included in the first optical module is the first light Outputting a signal; A photodiode element included in a first optical module receiving the first optical signal reflected on the specific body part; A second LED element included in the first optical module outputting a second optical signal; Receiving the second optical signal transmitted through the specific body part by a photodiode element included in the first optical module; A step in which the control IC included in the first optical module converts the first and second optical signals received by the photodiode element into reflected data and transmitted data in digital form, respectively; And analyzing the blood component by analyzing the reflection data and the transmission data by the control IC.

The non-invasive blood test apparatus of the present invention includes first and second optical modules facing each other with a specific body part interposed therebetween, wherein the first optical module includes a first LED element, a first photodiode element and a control IC. Including, the second optical module includes a second LED element and a second photodiode element, the first photodiode element, the first optical signal output from the first LED element to the specific body part Receiving the reflected first optical signal, the second optical signal output from the second LED element receives the second optical signal transmitted through the specific body part, respectively, the control IC, the first photo The first and second optical signals received by the diode element are respectively converted into reflection data and transmission data in digital form, and blood components are examined using the reflection data and the transmission data.

According to the non-invasive blood test apparatus of the present invention, a dual mode is supported to enable selection of any one of the transmissive test mode and the reflective test mode according to blood components, and measurement data measured in one test mode By using as the data for correcting the measured data measured in different inspection modes, it is possible to improve the reliability of the measured data.

In addition, according to the non-invasive blood test apparatus of the present invention, unlike a conventional method in which a single photodiode element and a plurality of LED elements are mounted on a substrate and implemented as a module, a plurality of LED elements are appropriately numbered. By separating and implementing with two modules, the board size can be reduced, and accordingly, it can be designed as a wearable device.

In addition, according to the non-invasive blood test apparatus of the present invention, the LED elements separated and mounted in two modules emit light sources of different wavelengths, thereby selectively measuring various blood components using light sources of various wavelengths. Can.

1 is a cross-sectional view of a non-invasive blood test apparatus according to an embodiment of the present invention.

Figure 2 is a block diagram of a non-invasive blood test apparatus according to an embodiment of the present invention.

3 is a block diagram showing the internal configuration of a control IC according to an embodiment of the present invention.

Figure 4 is a flow chart showing a non-invasive blood test method according to an embodiment of the present invention.

The present invention can be applied to various changes and can have various embodiments, and specific embodiments will be illustrated in the drawings and described in detail. However, this is not intended to limit the present invention to specific embodiments, and should be understood to include all modifications, equivalents, and substitutes included in the spirit and scope of the present invention.

The terms used in this application are only used to describe specific embodiments, and are not intended to limit the present invention. Singular expressions include plural expressions unless the context clearly indicates otherwise. In this application, the terms "include" or "have" are intended to indicate the presence of features, numbers, steps, actions, components, parts or combinations thereof described in the specification, but one or more other features. It should be understood that the existence or addition possibilities of fields or numbers, steps, operations, components, parts or combinations thereof are not excluded in advance.

Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by a person skilled in the art to which the present invention pertains. Terms such as those defined in a commonly used dictionary should be interpreted as having meanings consistent with meanings in the context of related technologies, and should not be interpreted as ideal or excessively formal meanings unless explicitly defined in the present application. Does not.

The present invention relates to a method for implementing an optical module, which is designed with two optical modules, and each module operates in a dual mode consisting of a transmissive inspection mode and a reflective inspection mode, and utilizes measurement results in each mode as a cross reference Therefore, there is a difference from the prior art in improving the reliability of measurement results. At this time, the light emitting elements dispersedly disposed in each optical module may analyze various blood components according to various wavelengths by outputting light signals (light sources) having various wavelengths. That is, by configuring the characteristic wavelength of a component to be measured among blood components in a singular or plural number, various blood components can be analyzed with multiple reaction wavelengths such as blood sugar, urea, cholesterol, and oxygen saturation. In addition, the present invention can be realized by miniaturization by distributing semiconductor-based low-cost optical elements in two optical modules, and can measure various body parts such as earlobe and hand, so that personalized health care is possible. ).

1, the non-invasive blood test apparatus 300 according to an embodiment of the present invention includes two optical modules (100, 200).

The two

optical modules

100 and 200 are disposed in a direction facing each other with the measurement object 10 representing a specific body part of a person interposed therebetween. The specific body part may be, for example, an ear ball, a finger, or the like.

The first optical module 100 includes a first substrate 110 and a light emitting element 111 and a light receiving element 113 mounted on the first substrate 110. The first substrate 110 may be a printed circuit board (PCB). The light emitting element 111 includes a plurality of LED elements. For simplicity of the drawing, only one LED element is shown in FIG. 1. The light receiving element 113 may be a photodiode element. A plurality of LED elements output light signals (light sources) having different wavelengths, respectively. The photodiode element 113 may receive an optical signal in which the optical signal output from each LED element is reflected on the measurement object 10. Also, the photodiode element 113 may receive an optical signal from which the light signal (light source) output from the light emitting element 211 included in the second optical module 200 passes through the measurement object 10. A case where the photodiode element 113 receives the reflected optical signal is defined as a'reflective inspection mode', and a case where the photodiode element 113 receives the transmitted optical signal is referred to as a'transmissive inspection mode'. define. In FIG. 1, a dotted line arrow indicates a movement path of the optical signal in the reflective inspection mode, and a solid line arrow indicates a movement path of the optical signal in the transmission inspection mode. The photodiode element 113 converts the optical signal received in the reflective inspection mode or the transmissive inspection mode into an electrical signal. The converted electrical signal is used to test blood components such as oxygen saturation, blood sugar, and urea.

Similar to the first optical module 100, the second optical module 200 includes a second substrate 210 and a light emitting element and a light receiving element mounted on the second substrate 210. The second substrate 210 may be a printed circuit board. The light emitting element 211 includes a plurality of LED elements. For simplicity of the drawing, only one LED element is shown in FIG. 1. The light receiving element 213 may be a photodiode element. A plurality of LED elements output light signals (light sources) having different wavelengths, respectively. The photodiode element 213 may receive an optical signal in which the optical signal output from each LED element is reflected on the measurement object 10. Also, the photodiode element 213 may receive an optical signal from which the light signal (light source) output from the light emitting element 111 included in the second optical module 200 passes through the measurement object 10. A case where the photodiode element 213 receives the reflected optical signal is defined as a'reflective inspection mode', and a case where the photodiode element 213 receives the transmitted optical signal is referred to as a'transmissive inspection mode'. define. The photodiode element 213 converts the optical signal received in the reflective inspection mode or the transmissive inspection mode into an electrical signal. The converted electrical signal is used to test blood components such as oxygen saturation, blood sugar, and urea.

As such, the non-invasive blood test apparatus according to an embodiment of the present invention is implemented with two

optical modules

100 and 200, unlike the conventional non-invasive blood test apparatus implemented with one optical module.

That is, the conventional non-invasive blood test apparatus is designed as one optical module including one photodiode element and a plurality of LED elements mounted on one substrate, while the non-invasive type according to an embodiment of the present invention The blood test apparatus 300 is configured to include two

optical modules

100 and 200 in which a plurality of LED elements are dispersedly disposed on two substrates and one photodiode is mounted on each substrate.

In the present invention, since the optical elements are dispersedly disposed on two substrates, the substrate size can be reduced, thereby miniaturizing the product and designing it as a wearable device.

Hereinafter, a non-invasive blood test apparatus according to an embodiment of the present invention will be described in more detail with reference to FIG. 2.

2 is a block diagram of a non-invasive blood test apparatus according to an embodiment of the present invention.

2, the non-invasive blood test apparatus according to an embodiment of the present invention includes two physically separated

optical modules

100 and 200 and a connecting member 150 connecting them. In this case, the connecting member may include a flexible cable for electrically connecting the two

optical modules

100 and 200.

As described in FIG. 1, each optical module includes a plurality of LED elements and a photodiode element. In this embodiment, the number of LED elements mounted in each optical module is limited to three. However, the present invention is not limited thereto, and the number of LED elements mounted in each optical module may be determined to be four or more by appropriately considering design variables such as design cost and substrate size.

The first optical module 100 includes a first substrate 110, first to first 1-3

LED elements

111A, 111B, and 111C mounted on the first substrate 110 and a first photodiode The devices 113 and PD1 are included, and further, a control IC 119 is further mounted on the first substrate 110. In this embodiment, the control IC 119 is described as being included in the first optical module 100, but may be included in the second optical module 200. That is, the control IC 119 may be mounted on the second substrate 210 of the second optical module 210.

The second optical module 200 includes a second substrate 210, 2-1 to 2-3

LED elements

111A, 111B, and 111C mounted on the second substrate 210 and a second photodiode And devices 213 and PD2.

The 1-1 to 1-3

LED elements

111A, 111B and 111C included in the first optical module 100 and the first photodiode element 113 are signals patterned on the first substrate 110. It is electrically connected to the control IC 119 by wiring.

The 2-1 to 2-3

LED elements

211A, 211B and 211C included in the second optical module 200 and the second photodiode element 213 are signals patterned on the second substrate 110 The control IC 119 is electrically connected to the wiring, the flexible cable included in the connecting member 150, and the signal wiring patterned on the first substrate 110.

The

LED elements

111A, 111B, 111C, 211A, 211B, and 211C are light emitting elements and output optical signals having different specific wavelengths, respectively. To this end, although not shown, each LED element may be configured to include a base substrate, an LED chip disposed on the base substrate, and a filter layer disposed on the LED chip. The LED chip includes an upper semiconductor layer, an active layer and a lower semiconductor layer. The active layer may be made of a gallium nitride-based compound to emit light. The filter layer may be a filter layer for selectively transmitting optical signals of a specific wavelength band. In this embodiment, by the filter layer, the spectral width of light emitted from the active layer may be set to the specific wavelength band (eg, 10 nm or less) centering on a specific wavelength. The filter layer may be implemented as, for example, a short-wave pass filter layer, a long-wave pass filter layer, or a bandpass filter layer.

Each of the first and

second photodiode devices

113 and 213 is a light-receiving device, and an indium gallium arsenide (InGaAs) or silicon-based photodiode device may be used. In the case of an InGaAs-based photodiode device, an optical signal of 700 to 1800 nm is received, and for a silicon-based photodiode, an optical signal of 400 to 1000 nm is received. Accordingly, the optical signal selectively output from each LED element is set to a wavelength within the above range.

The control IC 119 controls the overall operation (eg, dual mode, operation timing) of the

LED elements

111A, 111B, 111C, 211A, 211B, and 211C and the

photodiode elements

113, 213 at the same time. , Analyze the measurement data measured by the optical elements.

Hereinafter, the control IC 119 will be described in detail with reference to FIG. 3.

Referring to FIG. 3, the control IC 119 according to an embodiment of the present invention includes an input interface 31, a processor 32, a driving unit 33, an A/D conversion unit 34, a communication unit 35, and a memory (36).

The input interface 31 generates an ON signal indicating the start of the operation of the non-invasive blood test apparatus 300 in response to a user input, and inputs it to the processor 32.

The processor 32 controls and manages the overall operation of the peripheral components 31, 33, 34, 35 and 36. The processor 32 includes timing control logic 32A, data compensation logic 32B, and data analysis logic 32C.

The timing control logic 32A controls the operation timing of the

LED elements

111A, 111B, 111C, 211A, 211B and 211C and the

photodiode elements

113 and 213 in response to the on signal input from the input interface. do. Here, the operation timing includes an operation timing corresponding to the reflective inspection mode and an operation timing corresponding to the transmissive inspection mode. The operation timing corresponding to the reflective inspection mode and the operation timing corresponding to the transmissive inspection mode may alternately occur.

The operation timing corresponding to the reflective inspection mode may be divided into an operation timing of the first optical module 100 and an operation timing of the second optical module 200. At the operation timing of the first optical module 100 in the reflective inspection mode, the

LED elements

111A, 111B and 111C and the photodiode element 113 are activated, and the

LEDs

211A, 211B and 211C and the photodiode element 213 is deactivated. In addition, at the operation timing of the first optical module 100 in the reflective inspection mode, the

LED elements

111A, 111B, and 111C sequentially emit optical signals having different wavelengths at regular time intervals, and photodiodes. The element 113 sequentially receives the light signals emitted by the

LED elements

111A, 111B, and 111C reflected on a specific body part (10 in FIG. 1). Here, when the optical signals are simultaneously emitted, interference between the optical signals may occur. Therefore, in order to eliminate interference between optical signals, it is preferable that the

LED elements

111A, 111B and 111C are controlled to sequentially emit the optical signals.

Similarly, at the operation timing of the second optical module 200 in the reflective inspection mode, the

LED elements

111A, 111B and 111C and the photodiode element 113 are deactivated, and the

LED elements

211A, 211B and 211C ) And photodiode element 213 are activated. In addition, at the operation timing of the second optical module 200 in the reflective inspection mode, the

LED elements

211A, 211B, and 211C sequentially emit optical signals having different wavelengths at regular time intervals, and photodiodes The element 213 sequentially receives the light signals emitted by the

LED elements

211A, 211B, and 211C, reflected by a specific body part. The operation timing of the first optical module 100 and the operation timing of the second optical module 200 may alternately occur.

At the first operation timing corresponding to the transmissive inspection mode, the

LED elements

111A, 111B, 111C of the first optical module 100 and the photodiode element 213 of the second optical module 200 are activated, and The photodiodes 113 of the 1 optical module 100 and the

LED elements

211A, 211B, 211C of the second optical module 200 are deactivated. In the second operation timing corresponding to the transmissive inspection mode, on the contrary, the

LED elements

111A, 111B, 111C of the first optical module 100 and the photodiode element 213 of the second optical module 200 are deactivated, The photodiodes 113 of the first optical module 100 and the

LED elements

211A, 211B, 211C of the second optical module 200 are activated. The first and second operation timings corresponding to the transmissive inspection mode may alternately occur.

The timing control logic 32A inputs a timing signal corresponding to the operation timing corresponding to each inspection mode to the driver 33.

The driver 33 responds to the timing signal input from the timing control logic 32A, and displays the first driving signal corresponding to the reflective inspection mode and the second driving signal corresponding to the transmissive inspection mode as

LED elements

111A, 111B, 111C, 211A, 211B and 211C) and

photodiode elements

113 and 213. At this time, the driving unit 33 may alternately output the first and second driving signals according to the operation timing determined by the timing control logic.

The A/D conversion unit 34 includes a first electrical signal corresponding to the optical signal measured by the first photodiode element 113 and a second electrical signal corresponding to the optical signal measured by the second photodiode according to the operation timing. The signals are sequentially received, and the first and second electrical signals are sampled to generate first and second measurement data in digital form, and input them to the data compensation logic 32B in the processor 32.

Here, each of the first and second measurement data includes data measured in a reflective inspection mode (hereinafter, reflected data) and data measured in a transmissive inspection mode (transmissive data). Further, each of the reflected data and the transmitted data includes three measurement data corresponding to three optical signals (light sources) having different wavelengths.

The data compensation logic 32B in the processor 32 compensates the first and second measurement data inputted from the A/D conversion unit 34, and inputs the compensated measurement data to the data analysis logic 32C. . The compensation method may compensate, for example, transmission data included in the first measurement data using reflection data included in the first measurement data. For example, after calculating a difference value between a measurement value representing reflection data and a measurement value representing transmission data, the calculated difference value is set as a weight, and the measured value or transmission data representing reflection data is set using the set weight. The measured value indicated can be compensated. Alternatively, the average value between the measured value representing the reflected data and the measured value representing the transmitted data may be used as data for compensating the first measured data. In a similar way, the second measurement data can also be compensated. As described above, measurement data collected from each photodiode can be compensated to improve measurement reliability.

The data analysis logic 32C analyzes blood components based on the first and second measurement data compensated by the data compensation logic 32B. At this time, since each of the compensated measurement data is measured based on an optical signal having different wavelengths, multiple blood components can be analyzed by using multiple wavelengths as characteristic wavelengths of different blood. As described above, when combining optical signals having different wavelengths for the measurement of the same biological material, it can be used as a quasi-spectrum analyzer to further improve measurement reliability.

The analysis result data obtained by analyzing the compensated first and second measurement data by the data analysis logic 32C may be temporarily or permanently stored in the memory 36.

When the analysis result data is temporarily stored in the memory 36, the temporarily stored analysis result data is updated with the analysis result data obtained at the next measurement.

In addition, the analysis result data is input to the communication unit 35, the communication unit 35 wirelessly transmits the analysis result data to the user terminal in a wireless communication method, and the user is based on the analysis result data provided through the user terminal. Health status can be monitored. The wireless communication method may be short-range wireless communication such as Bluetooth or Wi-Fi. The communication unit 35 may be configured to include hardware components such as a modulator, an amplifier, and a filter to support wireless communication.

4 is a flowchart illustrating a non-invasive blood test method according to an embodiment of the present invention.

Referring to FIG. 4, first, in step S410, among the first and second

optical modules

100 and 200 facing each other with a specific body part 10 therebetween, the agent included in the first optical module 100 1 LED element 111 outputs a first optical signal.

Here, the first LED element 111 may include a plurality of LED elements, in which case, the plurality of LED elements output a plurality of optical signals having different wavelengths for various blood component tests, and the optical signals In order to prevent the interference of the liver, the on/off of the plurality of LED elements may be controlled by the control IC 119 according to an operation timing in which a plurality of optical signals are sequentially output (emitted).

Subsequently, in step S420, the photodiode element 113 included in the first optical module 100 receives the first optical signal reflected by the specific body part.

Subsequently, in step S430, the second LED element 211 included in the second optical module 200 outputs the second optical signal. Here, the second LED element 211 may also be composed of a plurality of LED elements, and in order to prevent interference between optical signals, the plurality of LEDs according to an operation timing in which a plurality of optical signals are sequentially output (emitted). The on/off of the elements can be controlled by the control IC 119.

Subsequently, in step S440, the photodiode element 113 included in the first optical module 100 receives the second optical signal transmitted through the specific body part 10.

Subsequently, in step S450, the control IC 119 included in the first optical module converts the first and second optical signals received by the photodiode element 113 into reflection data and transmission data in digital form, respectively. do.

Subsequently, in step S460, the control IC 119 analyzes the reflected data and the transmitted data to check blood components. Here, the control IC 119 may compensate the transmission data using the reflection data, or compensate the reflection data using the transmission data, and use the compensated reflection data or the compensated transmission data Analyze the blood components. As described above, as described above, the difference between the measured value representing the reflected data and the measured value representing the transmitted data is used as a weight to compensate for the measured value representing the reflected data or the measured value representing the transmitted data. Can.

The present invention can be implemented with hardware components, software components, and/or combinations of hardware components and software components. For example, the devices and components described in the embodiments may include, for example, processors, controllers, arithmetic logic units (ALUs), digital signal processors (micro signal processors), microcomputers, field programmable gate arrays (FPGAs). , A programmable logic unit (PLU), microprocessor, or any other device capable of executing and responding to instructions, may be implemented using one or more general purpose computers or special purpose computers.

The software may include a computer program, code, instruction, or a combination of one or more of these, and configure the processing device to operate as desired, or process independently or collectively You can command the device. Software and/or data may be interpreted by a processing device, or to provide instructions or data to a processing device, of any type of machine, component, physical device, virtual equipment, computer storage medium or device. , Or may be permanently or temporarily embodied in the transmitted signal wave. The software may be distributed on networked computer systems and stored or executed in a distributed manner. Software and data may be stored in one or more computer-readable recording media.

As described above, although the embodiments have been described by a limited embodiment and drawings, those skilled in the art can make various modifications and variations from the above description. For example, the described techniques are performed in a different order than the described method, and/or the components of the described system, structure, device, circuit, etc. are combined or combined in a different form from the described method, or other components Alternatively, proper results can be achieved even if replaced or substituted by equivalents. Therefore, other implementations, other embodiments, and equivalents to the claims are also within the scope of the following claims.

It is applicable to wearable devices and can be used for medical devices that analyze various blood components.

Claims

In a blood test method in a non-invasive blood test device,

Among the first and second optical modules facing each other with a specific body part therebetween, the first LED element included in the first optical module outputs a first optical signal;

A photodiode element included in a first optical module receiving the first optical signal reflected on the specific body part;

Outputting a second optical signal by a second LED element included in the second optical module;

Receiving the second optical signal transmitted through the specific body part by a photodiode element included in the first optical module;

The control IC included in the first optical module converts the first and second optical signals received by the photodiode device into reflection data and transmission data in digital form.

Converting each; And

The control IC analyzing the reflected data and the transmitted data to test blood components;

Blood test method in a non-invasive blood test device comprising a.
In claim 1,

The first and second LED elements include a plurality of LED elements,

The step of outputting the first optical signal by the first LED element,

Outputting the first optical signal including a plurality of optical signals having different wavelengths from the plurality of LED elements,

The step of outputting the second optical signal by the second LED element,

Outputting the second optical signal including the plurality of optical signals having different wavelengths from the plurality of LED elements.

A blood test method in a non-invasive blood test apparatus that is.
In claim 2,

The plurality of LED elements are sequentially turned on / off, the blood test method in a non-invasive blood test apparatus that sequentially outputs the plurality of optical signals.
In claim 1,

The step of examining the blood component,

Compensating the transmitted data using the reflected data or compensating the reflected data using the transmitted data; And

And analyzing the blood component using the compensated reflection data or the compensated transmission data.
The first and second optical modules facing each other with a specific body part therebetween,

The first optical module includes a first LED element, a first photodiode element and a control IC, and the second optical module includes a second LED element and a second photodiode element,

The first photodiode element,

The first optical signal output from the first LED element receives the first optical signal reflected on the specific body part, and the second optical signal output from the second LED element transmits the specific body part. Each receiving a second optical signal,

The control IC,

A ratio of converting the first and second optical signals received by the first photodiode device into reflection data and transmission data in digital form, respectively, and examining blood components using the reflection data and the transmission data. Invasive blood test device.
In claim 5,

Each of the first and second LED elements includes a plurality of LED elements,

The plurality of LED elements is a non-invasive blood test apparatus that outputs a plurality of optical signals having different wavelengths.
In claim 5,

The plurality of LED elements is a non-invasive blood test apparatus that sequentially outputs the plurality of optical signals.
In claim 5,

The control IC,

Compensating the transmission data using the reflection data, or compensating the reflection data using the transmission data, and examining the blood component using the compensated reflection data or the compensated transmission data. Type blood test device.