CN115989411A - 生物芯片、其制造方法及其使用 - Google Patents

生物芯片、其制造方法及其使用 Download PDF

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Publication number
CN115989411A
CN115989411A CN202180052075.2A CN202180052075A CN115989411A CN 115989411 A CN115989411 A CN 115989411A CN 202180052075 A CN202180052075 A CN 202180052075A CN 115989411 A CN115989411 A CN 115989411A
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China
Prior art keywords
biochip
substrate
group
substance
immobilized
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Pending
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CN202180052075.2A
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English (en)
Chinese (zh)
Inventor
泽野惠梨香
高濑雄希
酒井悠
田代英夫
田代朋子
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Mitsubishi Gas Chemical Co Inc
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Mitsubishi Gas Chemical Co Inc
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Publication of CN115989411A publication Critical patent/CN115989411A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202180052075.2A 2020-09-07 2021-09-06 生物芯片、其制造方法及其使用 Pending CN115989411A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-150138 2020-09-07
JP2020150138 2020-09-07
PCT/JP2021/032732 WO2022050418A1 (ja) 2020-09-07 2021-09-06 バイオチップ、その製造方法及びその使用

Publications (1)

Publication Number Publication Date
CN115989411A true CN115989411A (zh) 2023-04-18

Family

ID=80492004

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180052075.2A Pending CN115989411A (zh) 2020-09-07 2021-09-06 生物芯片、其制造方法及其使用

Country Status (5)

Country Link
US (1) US20230241601A1 (https=)
EP (1) EP4212875A4 (https=)
JP (1) JPWO2022050418A1 (https=)
CN (1) CN115989411A (https=)
WO (1) WO2022050418A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022168870A1 (ja) * 2021-02-03 2022-08-11 積水化学工業株式会社 細胞培養用マイクロキャリア及び細胞の培養方法
CN115541895B (zh) * 2022-11-29 2023-05-19 天津德祥生物技术股份有限公司 一种提高微流控反定检测卡灵敏度的配方液及应用

Citations (5)

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JP2005509127A (ja) * 2000-11-27 2005-04-07 インテリジェント メディカル ディバイシーズ エル．エル． シー． 臨床的にインテリジェントな診断装置および方法
JP2009192232A (ja) * 2008-02-12 2009-08-27 Panasonic Corp 磁性粒子アレイの作製装置および磁性粒子アレイの作製方法
JP2012159335A (ja) * 2011-01-31 2012-08-23 National Institute Of Advanced Industrial & Technology 微粒子のアレイ化法および装置
CN110325858A (zh) * 2017-02-24 2019-10-11 三菱瓦斯化学株式会社 生物物质固定化方法及其利用
CN111033259A (zh) * 2017-09-07 2020-04-17 三菱瓦斯化学株式会社 生物芯片用基体、生物芯片、生物芯片的制造方法及其保存方法

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DE19782097T1 (de) * 1996-11-06 1999-10-14 Sequenom Inc Zusammensetzungen und Verfahren zur Immobilisierung von Nucleinsäuren an feste Träger
JP3945192B2 (ja) * 2001-06-27 2007-07-18 富士通株式会社 割引の組み合わせ方法および組み合わせプログラム
US20030044801A1 (en) * 2001-09-05 2003-03-06 Harvey Thomas B. Array using microspheres
JP2008231013A (ja) * 2007-03-20 2008-10-02 Kaneka Corp 固定化糖鎖体
JP5559465B2 (ja) 2008-06-17 2014-07-23 株式会社日立製作所 アビジン類結合担体、その製造方法及びその使用方法
JP2011053334A (ja) 2009-08-31 2011-03-17 Housetec Inc 成形構造体
US12379376B2 (en) * 2018-12-03 2025-08-05 University Of Notre Dame Du Lac Biosensor and method for detection of analytes
JP7346855B2 (ja) 2019-03-13 2023-09-20 富士電機株式会社 半導体装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005509127A (ja) * 2000-11-27 2005-04-07 インテリジェント メディカル ディバイシーズ エル．エル． シー． 臨床的にインテリジェントな診断装置および方法
JP2009192232A (ja) * 2008-02-12 2009-08-27 Panasonic Corp 磁性粒子アレイの作製装置および磁性粒子アレイの作製方法
JP2012159335A (ja) * 2011-01-31 2012-08-23 National Institute Of Advanced Industrial & Technology 微粒子のアレイ化法および装置
CN110325858A (zh) * 2017-02-24 2019-10-11 三菱瓦斯化学株式会社 生物物质固定化方法及其利用
CN111033259A (zh) * 2017-09-07 2020-04-17 三菱瓦斯化学株式会社 生物芯片用基体、生物芯片、生物芯片的制造方法及其保存方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
（英）（威尔逊）KEITH WILSON，（英）（沃克尔）JOHN WALKER编，屈伸主译: "实用生物化学原理和技术 第5版", 31 January 2006, 中国医药科技出版社, pages: 203 - 204 *
夏启中: "基因工程", 31 July 2007, 中国农业出版社, pages: 119 *
陈智毅 等: "分子影像学 基础与应用", 31 January 2013, 广东高等教育出版社, pages: 161 *

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WO2022050418A1 (ja) 2022-03-10
JPWO2022050418A1 (https=) 2022-03-10
US20230241601A1 (en) 2023-08-03
EP4212875A1 (en) 2023-07-19
EP4212875A4 (en) 2024-03-13

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