CN115956573A - Novel bactericidal composition containing chlorothalonil - Google Patents
Novel bactericidal composition containing chlorothalonil Download PDFInfo
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- CN115956573A CN115956573A CN202211614651.0A CN202211614651A CN115956573A CN 115956573 A CN115956573 A CN 115956573A CN 202211614651 A CN202211614651 A CN 202211614651A CN 115956573 A CN115956573 A CN 115956573A
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- 239000005747 Chlorothalonil Substances 0.000 title claims abstract description 86
- CRQQGFGUEAVUIL-UHFFFAOYSA-N chlorothalonil Chemical compound ClC1=C(Cl)C(C#N)=C(Cl)C(C#N)=C1Cl CRQQGFGUEAVUIL-UHFFFAOYSA-N 0.000 title claims abstract description 86
- 239000000203 mixture Substances 0.000 title claims abstract description 59
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 57
- 230000002195 synergetic effect Effects 0.000 claims abstract description 43
- 239000008139 complexing agent Substances 0.000 claims abstract description 42
- -1 polyhexamethylene guanidine hydrochloride Polymers 0.000 claims abstract description 30
- 239000000645 desinfectant Substances 0.000 claims abstract description 21
- 239000006068 taste-masking agent Substances 0.000 claims abstract description 21
- 239000004094 surface-active agent Substances 0.000 claims abstract description 20
- 241000209140 Triticum Species 0.000 claims abstract description 16
- 235000021307 Triticum Nutrition 0.000 claims abstract description 16
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 12
- 239000008367 deionised water Substances 0.000 claims description 11
- 229910021641 deionized water Inorganic materials 0.000 claims description 11
- 239000011550 stock solution Substances 0.000 claims description 10
- RUPBZQFQVRMKDG-UHFFFAOYSA-M Didecyldimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC RUPBZQFQVRMKDG-UHFFFAOYSA-M 0.000 claims description 9
- 229960004670 didecyldimethylammonium chloride Drugs 0.000 claims description 9
- 235000020221 chamomile extract Nutrition 0.000 claims description 8
- 229940119217 chamomile extract Drugs 0.000 claims description 8
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 8
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 8
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 claims description 8
- 235000019982 sodium hexametaphosphate Nutrition 0.000 claims description 8
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims description 8
- 229960000686 benzalkonium chloride Drugs 0.000 claims description 5
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims description 5
- UMGXUWVIJIQANV-UHFFFAOYSA-M didecyl(dimethyl)azanium;bromide Chemical compound [Br-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC UMGXUWVIJIQANV-UHFFFAOYSA-M 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 235000005979 Citrus limon Nutrition 0.000 claims description 4
- 244000131522 Citrus pyriformis Species 0.000 claims description 4
- 230000000855 fungicidal effect Effects 0.000 claims description 4
- 229930182470 glycoside Natural products 0.000 claims description 4
- 235000006408 oxalic acid Nutrition 0.000 claims description 4
- 229940069521 aloe extract Drugs 0.000 claims description 3
- LQPLDXQVILYOOL-UHFFFAOYSA-I pentasodium;2-[bis[2-[bis(carboxylatomethyl)amino]ethyl]amino]acetate Chemical group [Na+].[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC(=O)[O-])CCN(CC([O-])=O)CC([O-])=O LQPLDXQVILYOOL-UHFFFAOYSA-I 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 22
- 238000002360 preparation method Methods 0.000 abstract description 13
- 239000000575 pesticide Substances 0.000 abstract description 4
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 13
- VKTHZHSHTVVWPN-UHFFFAOYSA-N [Na].[Na].[Na].[Na].[Na].CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.NCCNCCN Chemical group [Na].[Na].[Na].[Na].[Na].CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.NCCNCCN VKTHZHSHTVVWPN-UHFFFAOYSA-N 0.000 description 7
- 230000002265 prevention Effects 0.000 description 6
- 239000003899 bactericide agent Substances 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- VYTBPJNGNGMRFH-UHFFFAOYSA-N acetic acid;azane Chemical compound N.N.CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O VYTBPJNGNGMRFH-UHFFFAOYSA-N 0.000 description 3
- MMUFAGXJPKNAHT-UHFFFAOYSA-N copper;quinolin-8-ol Chemical compound [Cu].C1=CN=C2C(O)=CC=CC2=C1 MMUFAGXJPKNAHT-UHFFFAOYSA-N 0.000 description 3
- 230000000361 pesticidal effect Effects 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 208000031888 Mycoses Diseases 0.000 description 2
- 230000000711 cancerogenic effect Effects 0.000 description 2
- 231100000357 carcinogen Toxicity 0.000 description 2
- 239000003183 carcinogenic agent Substances 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 230000002538 fungal effect Effects 0.000 description 2
- 229940071089 sarcosinate Drugs 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- OWEFQTXQEHYDEJ-UHFFFAOYSA-N 2,3-dihydroxypropanal diphosphono hydrogen phosphate Chemical compound OCC(O)C=O.OP(O)(=O)OP(O)(=O)OP(O)(O)=O OWEFQTXQEHYDEJ-UHFFFAOYSA-N 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 231100000674 Phytotoxicity Toxicity 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000014104 aloe vera supplement Nutrition 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 239000000447 pesticide residue Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000012747 synergistic agent Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the field of pesticides, and particularly discloses a novel bactericidal composition containing chlorothalonil and a preparation method thereof, wherein the composition contains polyhexamethylene guanidine hydrochloride and chlorothalonil, and the mass ratio of the polyhexamethylene guanidine hydrochloride to the chlorothalonil is 100:15-25; further, the coating comprises the following components in parts by weight: 100 parts of polyhexamethylene guanidine hydrochloride, 15-25 parts of chlorothalonil, 5-10 parts of synergistic disinfectant, 4-8 parts of complexing agent, 2-4 parts of synergistic complexing agent, 1-2 parts of surfactant and 5-10 parts of taste masking agent; the novel bactericidal composition containing chlorothalonil disclosed by the invention can greatly reduce the using amount of the chlorothalonil and reduce the cost under the condition of not reducing the bactericidal effect of the chlorothalonil, and the composition is convenient to prepare, good in solubility, convenient to use and good in effect of preventing and treating leaf rust of wheat.
Description
Technical Field
The invention belongs to the field of pesticides, and particularly discloses a novel bactericidal composition containing chlorothalonil and a preparation method thereof.
Background
Wheat is one of the main grain crops planted in China. The current bactericide varieties used for preventing and treating the field diseases of main grain crops such as wheat and the like have the defects of large using amount and strong drift; and the long-term single use of the bactericide can cause the increase of the drug resistance of various field diseases, and secondly, the use cost of the existing bactericide is high.
Chlorothalonil, also known as 2,4,5, 6-tetrachloro-1, 3-benzenedinitrile, is an organic compound having the chemical formula C8Cl4N2, and is a broad-spectrum protective fungicide. The chlorothalonil can act with glyceraldehyde triphosphate dehydrogenase in fungal cells, and is combined with protein containing cysteine in the enzyme, so that the activity of the enzyme is damaged, and the metabolism of the fungal cells is damaged and loses vitality. Chlorothalonil has no internal absorption and conduction effects, but has good adhesion on the body surface after being sprayed on plants, and is not easy to be washed away by rainwater, so the pesticide effect period is longer. Chlorothalonil is a high-efficiency low-toxicity broad-spectrum bactericide, has a prevention effect on various crop fungal diseases, and has stable pesticide effect and long residual effect period. The chlorothalonil can be used for crops such as wheat, rice, vegetables, fruit trees, peanuts, tea leaves and the like, particularly can be used for wheat to prevent leaf rust, but the reference of the primary arrangement of carcinogen lists published by the international cancer research institution of the world health organization is provided, and the chlorothalonil is in a class 2B carcinogen list, so that the increase of a synergistic agent can be considered to reduce the dosage of the chlorothalonil. CN202010441472.6 discloses a oxine-copper and chlorothalonil compound bactericidal composition and application thereof, wherein the oxine-copper and chlorothalonil are compounded for use, and compared with the existing single preparation, the composition has an obvious synergistic control effect, can control multiple field phytotoxicity simultaneously, is low in dosage, reduces the pollution of pesticide residues to the environment, and plays a positive role in protecting the ecological environment. However, in the above composition, oxine-copper is relatively low in toxicity, but is relatively expensive, insoluble in most solvents, and easily decomposed and deteriorated at high temperatures, and thus is significantly limited in practical use.
Disclosure of Invention
In order to solve the problems, the invention discloses a novel bactericidal composition containing chlorothalonil.
The technical scheme of the invention is as follows:
a novel bactericidal composition containing chlorothalonil, which contains polyhexamethylene guanidine hydrochloride and chlorothalonil, wherein the mass ratio of the polyhexamethylene guanidine hydrochloride to the chlorothalonil is 100:15-25.
In some embodiments, the novel bactericidal composition containing chlorothalonil in the scheme has a good control effect on leaf blight and leaf rust, and particularly the control effect on leaf rust is over 90%.
Further, the novel bactericidal composition containing chlorothalonil comprises the following components in parts by weight:
in the scheme, the complexing agent and the synergistic complexing agent play a role in coordination, so that the polyhexamethylene guanidine hydrochloride and the chlorothalonil are co-dissolved in a coexistence manner, no precipitation occurs, and the application is easy.
Further, according to the novel bactericidal composition containing chlorothalonil, the synergistic disinfectant is one or more of benzalkonium chloride, didecyldimethyl ammonium chloride and didecyldimethyl ammonium bromide in parts by weight.
Further, the novel bactericidal composition containing chlorothalonil is characterized in that the synergistic disinfectant is one or more of benzalkonium chloride, didecyldimethyl ammonium chloride and didecyldimethyl ammonium bromide.
Furthermore, the complexing agent is selected from one of diamine tetraacetic acid disodium, sodium hexametaphosphate and oxalic acid.
Furthermore, the novel bactericidal composition containing chlorothalonil is characterized in that the synergistic complexing agent is selected from pentasodium diethylenetriaminepentaacetate.
Further, in the novel bactericidal composition containing chlorothalonil, the surfactant is one or more selected from alkyl glycoside, cocamidopropyl betaine and N-acyl sarcosinate.
Further, the novel bactericidal composition containing chlorothalonil is characterized in that the taste masking agent is one or more selected from lemon extract, chamomile extract and aloe extract. The use of taste masking agents can mask the smell of pesticides that are too intense.
Further, the novel bactericidal composition containing chlorothalonil comprises the following components in parts by weight:
in some embodiments, compared with the method of completely using chlorothalonil or completely using polyhexamethylene guanidine hydrochloride or reducing the use of chlorothalonil, the method has the advantages that the control effects on wheat leaf blight and leaf rust are greatly improved, and the chlorothalonil and the polyhexamethylene guanidine hydrochloride in the novel bactericidal composition have an excellent synergistic effect, so that the use amount of the chlorothalonil can be greatly reduced, and a better control effect can be achieved.
Further, the preparation method of the novel bactericidal composition containing chlorothalonil comprises the following steps:
putting polyhexamethylene guanidine hydrochloride, chlorothalonil, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, adding deionized water with the weight being 10-20 times that of the components, and preparing into a stock solution. The preparation method is only needed at normal temperature, does not need special equipment, has low preparation cost and is easy to popularize.
Furthermore, the novel bactericidal composition containing chlorothalonil is applied to the control of wheat leaf rust.
Compared with the prior art, the invention has the following beneficial effects:
the invention discloses a novel bactericidal composition containing chlorothalonil, wherein polyhexamethylene guanidine hydrochloride and chlorothalonil are matched for use, so that the low-cost polyhexamethylene guanidine hydrochloride can greatly promote the bactericidal effect of the chlorothalonil, and particularly, the combined effect of the polyhexamethylene guanidine hydrochloride and the chlorothalonil is great and the effect of respectively using the polyhexamethylene guanidine hydrochloride or the chlorothalonil aiming at the fungal disease of leaf rust of wheat; the composition can greatly reduce the using amount of chlorothalonil, better exerts the antifungal effect of the chlorothalonil, and has good solubility in water, convenient use and low cost.
Drawings
FIG. 1 is a comparison of the control effects of the bactericidal composition on wheat leaf blight in the test examples;
FIG. 2 is a comparison of the control effect of the bactericidal composition on wheat leaf rust in the test examples.
Detailed Description
A novel bactericidal composition containing chlorothalonil is characterized by comprising the following components in parts by weight:
the synergistic disinfectant is one or more selected from benzalkonium chloride, didecyl dimethyl ammonium chloride and didecyl dimethyl ammonium bromide.
The complexing agent is selected from one of diamine tetraacetic acid disodium, sodium hexametaphosphate and oxalic acid.
The synergistic complexing agent is selected from diethylenetriamine pentaacetic acid pentasodium.
The surfactant is selected from one or more of alkyl glycoside, cocamidopropyl betaine and N-acyl sarcosinate.
The taste masking agent is selected from one or more of lemon extract, chamomile extract and aloe extract.
The preparation method of the novel bactericidal composition containing chlorothalonil comprises the following steps:
putting polyhexamethylene guanidine hydrochloride, chlorothalonil, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, and adding deionized water with the weight being 10-20 times that of the components to prepare a stock solution.
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
The reagents or instruments used in the examples of the present invention are not indicated by manufacturers, and are all conventional reagent products commercially available.
Example 1
A novel bactericidal composition containing chlorothalonil comprises the following components in parts by weight:
the synergistic disinfectant is selected from benzalkonium chloride.
The complexing agent is selected from diamine tetraacetic acid disodium.
The synergistic complexing agent is selected from diethylenetriamine pentaacetic acid pentasodium.
The surfactant is selected from alkyl glycosides.
The taste-masking agent is selected from lemon extract.
The preparation method of the novel bactericidal composition containing chlorothalonil comprises the following steps:
putting polyhexamethylene guanidine hydrochloride, chlorothalonil, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, and adding deionized water with the weight being 10 times that of the components to prepare a stock solution.
Example 2
A novel bactericidal composition containing chlorothalonil comprises the following components in parts by weight:
the synergistic disinfectant is selected from didecyl dimethyl ammonium chloride.
The complexing agent is selected from sodium hexametaphosphate.
The co-complexing agent is selected from diethylenetriamine pentaacetic acid pentasodium.
The surfactant is selected from cocamidopropyl betaine.
The taste-masking agent is selected from chamomile extract.
The preparation method of the novel bactericidal composition containing chlorothalonil comprises the following steps:
putting polyhexamethylene guanidine hydrochloride, chlorothalonil, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, and adding deionized water with the weight 15 times that of the components to prepare a stock solution.
Example 3
A novel bactericidal composition containing chlorothalonil comprises the following components in parts by weight:
the synergistic disinfectant is selected from didecyl dimethyl ammonium bromide.
The complexing agent is selected from oxalic acid.
The synergistic complexing agent is selected from diethylenetriamine pentaacetic acid pentasodium.
The surfactant is selected from N-acyl sarcosinates.
The taste masking agent is selected from aloe vera extract.
The preparation method of the novel bactericidal composition containing chlorothalonil comprises the following steps:
putting polyhexamethylene guanidine hydrochloride, chlorothalonil, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, adding deionized water with the weight being 20 times that of the components, and preparing a stock solution.
Comparative example 1
A novel bactericidal composition containing chlorothalonil comprises the following components in parts by weight:
the synergistic disinfectant is selected from didecyl dimethyl ammonium chloride.
The complexing agent is selected from sodium hexametaphosphate.
The synergistic complexing agent is selected from diethylenetriamine pentaacetic acid pentasodium.
The surfactant is selected from cocamidopropyl betaine.
The taste masking agent is selected from chamomile extract.
The preparation method of the novel bactericidal composition containing chlorothalonil comprises the following steps:
putting chlorothalonil, the synergistic disinfectant, the complexing agent, the synergistic complexing agent, the surfactant and the taste masking agent into a stirrer, uniformly mixing, and adding deionized water with the weight being 15 times that of the components to prepare a stock solution.
This comparative example differs from example 2 in that 100 parts of chlorothalonil are used instead of 100 parts of polyhexamethyleneguanidine hydrochloride.
Comparative example 2
The novel bactericidal composition comprises the following components in parts by weight:
the synergistic disinfectant is selected from didecyl dimethyl ammonium chloride.
The complexing agent is selected from sodium hexametaphosphate.
The synergistic complexing agent is selected from diethylenetriamine pentaacetic acid pentasodium.
The surfactant is selected from cocamidopropyl betaine.
The taste-masking agent is selected from chamomile extract.
The preparation method of the novel bactericidal composition comprises the following steps:
putting polyhexamethylene guanidine hydrochloride, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, and adding deionized water 15 times the weight of the components to prepare a stock solution.
This comparative example differs from example 2 in that 20 parts of polyhexamethyleneguanidine hydrochloride are used instead of 20 parts of chlorothalonil.
Comparative example 3
A novel bactericidal composition containing chlorothalonil comprises the following components in parts by weight:
the synergistic disinfectant is selected from didecyl dimethyl ammonium chloride.
The complexing agent is selected from sodium hexametaphosphate.
The synergistic complexing agent is selected from diethylenetriamine pentaacetic acid pentasodium.
The surfactant is selected from cocamidopropyl betaine.
The taste-masking agent is selected from chamomile extract.
The preparation method of the novel bactericidal composition containing chlorothalonil comprises the following steps:
putting deionized water, chlorothalonil, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, and adding deionized water with the weight 15 times that of the components to prepare a stock solution.
This comparative example differs from example 2 in that 100 parts of polyhexamethyleneguanidine hydrochloride are replaced by 100 parts of deionized water.
Test example 1
The stock solutions prepared in examples 1 to 3 and comparative examples 1 to 3 were used to test the control effects on wheat leaf blight and leaf rust.
The method comprises the following specific steps: the bactericidal compositions of examples 1-6 and comparative examples 1-2 are sprayed in different planting areas, wherein the application amount of the bactericidal compositions of examples 1-3 and comparative examples 1-3 is 100 raw solution g/mu, the area of the planting area of each bactericidal composition is 1 mu when being tested, the bactericidal composition is diluted by water until the spraying amount per mu is 50L when being applied, and meanwhile, the bactericidal composition is sprayed by clear water as a blank treatment, and other planting conditions of all the planting areas are basically the same except that the bactericidal composition is applied according to the scheme. The control effect of leaf rust on wheat is investigated 30 days after application of the pesticide, and the specific test method is carried out according to the pesticide effect experimental criteria among agricultural crops. Sampling is carried out at random for 5 points in each planting area, 25 columns of wheat are investigated in each planting area, the prevention and control effects of leaf blight and leaf rust of the wheat in various planting areas are investigated, the disease index is calculated according to the formula (1), and the prevention and control effects are calculated according to the formula (2). Specific results are shown in table 1:
disease index = (all levels of diseased plant or leaf tree x represents number)/∑ (plant or leaf tree x highest representative level value) × 100% formula (1)
Control effect = (control area after epidemic situation prevention index-treatment area after epidemic situation prevention index)/control area after epidemic situation prevention index x 100% formula (2)
TABLE 1 control Effect on wheat leaf blight and leaf rust
From the data of examples 1 to 3, comparative examples 1 to 3 and blank controls, the novel bactericidal composition containing chlorothalonil disclosed by the invention has better control effects on leaf blight and leaf rust, particularly the control effect on leaf rust is over 90%, and compared with the method of completely using chlorothalonil (comparative example 1), completely using polyhexamethylene guanidine hydrochloride (comparative example 2) or reducing the use amount of chlorothalonil (comparative example 3), the invention has great improvement, so that the chlorothalonil and the polyhexamethylene guanidine hydrochloride in the novel bactericidal composition generate excellent synergistic effect, the using amount of chlorothalonil can be greatly reduced, and the better control effect is obtained.
There are a limited number of preferred embodiments of the invention which are described in greater detail and detail, but are not to be construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.
Claims (10)
1. The novel bactericidal composition containing chlorothalonil is characterized by comprising polyhexamethylene guanidine hydrochloride and chlorothalonil, wherein the mass ratio of the polyhexamethylene guanidine hydrochloride to the chlorothalonil is 100:15-25.
2. The novel bactericidal composition containing chlorothalonil according to claim 1, which is characterized by consisting of the following components in parts by weight:
polyhexamethylene guanidine hydrochloride 100 parts
Chlorothalonil 15-25 parts
5-10 parts of synergistic disinfectant
4-8 parts of complexing agent
2-4 parts of synergistic complexing agent
1-2 parts of surfactant
5-10 parts of taste masking agent.
3. The novel bactericidal composition containing chlorothalonil according to claim 2, wherein the synergistic disinfectant is selected from one or more of benzalkonium chloride, didecyldimethylammonium chloride and didecyldimethylammonium bromide.
4. The novel chlorothalonil-containing fungicidal composition according to claim 2, wherein the complexing agent is selected from one of disodium ethylenediaminetetraacetate, sodium hexametaphosphate and oxalic acid.
5. The novel chlorothalonil-containing bactericidal composition according to claim 2, wherein the co-complexing agent is selected from pentasodium diethylenetriaminepentaacetate.
6. The novel bactericidal composition containing chlorothalonil according to claim 2, wherein the surfactant is selected from one or more of alkyl glycosides, cocamidopropyl betaine, and N-acyl sarcosinates.
7. The novel bactericidal composition containing chlorothalonil according to claim 2, wherein the taste masking agent is selected from one or more of lemon extract, chamomile extract and aloe extract.
8. The novel bactericidal composition containing chlorothalonil according to claim 2, which is characterized by comprising the following components in parts by weight:
polyhexamethylene guanidine hydrochloride 100 parts
Chlorothalonil 15-25 parts
5-10 parts of didecyl dimethyl ammonium chloride
4-8 parts of sodium hexametaphosphate
2-4 parts of diethylene triamine pentaacetic acid pentasodium salt
1-2 parts of cocamidopropyl betaine
5-10 parts of chamomile extract.
9. The method for preparing a novel fungicidal composition containing chlorothalonil according to any one of claims 1 to 8, comprising the steps of:
putting polyhexamethylene guanidine hydrochloride, chlorothalonil, a synergistic disinfectant, a complexing agent, a synergistic complexing agent, a surfactant and a taste masking agent into a stirrer, uniformly mixing, adding deionized water with the weight being 10-20 times that of the components, and preparing into a stock solution.
10. Use of the novel fungicidal composition containing chlorothalonil according to any one of claims 1 to 8 for the control of wheat leaf rust.
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| CN1883896A (en) * | 2006-06-13 | 2006-12-27 | 上海大不同木业科技有限公司 | Wood protective agent |
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| CN108366565A (en) * | 2015-09-25 | 2018-08-03 | 弗莱克西格专利有限责任公司 | New plant protection composition and its application |
| CN111449072A (en) * | 2020-05-22 | 2020-07-28 | 利民化学有限责任公司 | Oxine-copper and chlorothalonil compound sterilization composition and application thereof |
| CN114931138A (en) * | 2021-10-13 | 2022-08-23 | 深圳市华宝生物材料科技有限公司 | Sterilization disinfectant and preparation method thereof |
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| CN1883896A (en) * | 2006-06-13 | 2006-12-27 | 上海大不同木业科技有限公司 | Wood protective agent |
| CN103098817A (en) * | 2012-12-30 | 2013-05-15 | 湖南农大海特农化有限公司 | Pesticidal composition of biguanide trioctyl alkylbenzene sulfonate and chlorothalonil |
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