CN115955969A - 用于口服治疗白血病的组合物和方法 - Google Patents
用于口服治疗白血病的组合物和方法 Download PDFInfo
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- CN115955969A CN115955969A CN202180038959.2A CN202180038959A CN115955969A CN 115955969 A CN115955969 A CN 115955969A CN 202180038959 A CN202180038959 A CN 202180038959A CN 115955969 A CN115955969 A CN 115955969A
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
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- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2021/027702 WO2022220841A1 (fr) | 2021-04-16 | 2021-04-16 | Composition et méthode de traitement oral de la leucémie |
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| JP (1) | JP7525638B2 (fr) |
| KR (1) | KR20230171854A (fr) |
| CN (1) | CN115955969A (fr) |
| AU (1) | AU2021440597A1 (fr) |
| CA (1) | CA3175637A1 (fr) |
| MX (1) | MX2022012945A (fr) |
| WO (1) | WO2022220841A1 (fr) |
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| US7648695B2 (en) * | 1998-08-06 | 2010-01-19 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
| KR20070022308A (ko) * | 2004-05-10 | 2007-02-26 | 로버트 에프 호프만 | 암 치료용 약제학적 조성물 |
| CN102482347B (zh) * | 2009-01-12 | 2017-04-26 | 希托马克斯医疗有限责任公司 | 修饰抗体组合物及其制备和使用方法 |
| US8765725B2 (en) * | 2012-05-08 | 2014-07-01 | Aciex Therapeutics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
| WO2018047917A1 (fr) * | 2016-09-09 | 2018-03-15 | 国立大学法人 東京大学 | Effet antitumoral synergétique d'une combinaison de la protéine hmg, de l'anticorps anti-cd4 ou d'un agent de contrôle de point de contrôle immunitaire |
| CA3059882A1 (fr) * | 2017-04-12 | 2018-10-18 | Aura Biosciences, Inc. | Polytherapie ciblee |
| AU2018254577B2 (en) * | 2017-04-21 | 2024-06-13 | Epizyme, Inc. | Combination therapies with EHMT2 inhibitors |
| EP3773548B1 (fr) * | 2018-05-16 | 2023-08-09 | Provectus Pharmatech, Inc. | Activité antitumorale in vitro et de xénogreffe d'un xanthène halogéné contre des tumeurs solides pédiatriques réfractaires |
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- 2021-04-16 EP EP21935450.3A patent/EP4117668A4/fr active Pending
- 2021-04-16 WO PCT/US2021/027702 patent/WO2022220841A1/fr unknown
- 2021-04-16 JP JP2022562946A patent/JP7525638B2/ja active Active
- 2021-04-16 CN CN202180038959.2A patent/CN115955969A/zh active Pending
- 2021-04-16 KR KR1020227039851A patent/KR20230171854A/ko active Search and Examination
- 2021-04-16 AU AU2021440597A patent/AU2021440597A1/en active Pending
- 2021-04-16 CA CA3175637A patent/CA3175637A1/fr active Pending
- 2021-04-16 MX MX2022012945A patent/MX2022012945A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP7525638B2 (ja) | 2024-07-30 |
| MX2022012945A (es) | 2023-03-16 |
| CA3175637A1 (fr) | 2022-10-20 |
| EP4117668A1 (fr) | 2023-01-18 |
| AU2021440597A1 (en) | 2022-11-10 |
| WO2022220841A1 (fr) | 2022-10-20 |
| EP4117668A4 (fr) | 2023-12-06 |
| KR20230171854A (ko) | 2023-12-21 |
| JP2023529262A (ja) | 2023-07-10 |
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