CN115943961A - Bactericide composition containing chlorofluoromethane and oxine-copper and application thereof - Google Patents
Bactericide composition containing chlorofluoromethane and oxine-copper and application thereof Download PDFInfo
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- CN115943961A CN115943961A CN202211194620.4A CN202211194620A CN115943961A CN 115943961 A CN115943961 A CN 115943961A CN 202211194620 A CN202211194620 A CN 202211194620A CN 115943961 A CN115943961 A CN 115943961A
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- Prior art keywords
- oxine
- copper
- pesticide
- mass
- bactericide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 54
- MMUFAGXJPKNAHT-UHFFFAOYSA-N copper;quinolin-8-ol Chemical compound [Cu].C1=CN=C2C(O)=CC=CC2=C1 MMUFAGXJPKNAHT-UHFFFAOYSA-N 0.000 title claims abstract description 48
- 239000000203 mixture Substances 0.000 title claims abstract description 44
- 239000003899 bactericide agent Substances 0.000 title claims abstract description 31
- XWCDCDSDNJVCLO-UHFFFAOYSA-N Chlorofluoromethane Chemical compound FCCl XWCDCDSDNJVCLO-UHFFFAOYSA-N 0.000 title description 20
- 239000000575 pesticide Substances 0.000 claims abstract description 42
- 201000010099 disease Diseases 0.000 claims abstract description 38
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 38
- 244000061456 Solanum tuberosum Species 0.000 claims abstract description 35
- 235000002595 Solanum tuberosum Nutrition 0.000 claims abstract description 35
- 240000008067 Cucumis sativus Species 0.000 claims abstract description 23
- 230000001954 sterilising effect Effects 0.000 claims abstract description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 4
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims description 24
- 240000003768 Solanum lycopersicum Species 0.000 claims description 24
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 9
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 6
- 239000002562 thickening agent Substances 0.000 claims description 5
- 239000002270 dispersing agent Substances 0.000 claims description 4
- 230000000855 fungicidal effect Effects 0.000 claims description 4
- 239000000417 fungicide Substances 0.000 claims description 4
- 230000000361 pesticidal effect Effects 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 230000002335 preservative effect Effects 0.000 claims description 4
- 239000000080 wetting agent Substances 0.000 claims description 4
- 229960002842 clobetasol Drugs 0.000 claims 3
- CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 claims 3
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 claims 1
- 230000002528 anti-freeze Effects 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 29
- 230000002265 prevention Effects 0.000 abstract description 8
- 239000004480 active ingredient Substances 0.000 abstract description 6
- 244000052616 bacterial pathogen Species 0.000 abstract description 6
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- 230000007246 mechanism Effects 0.000 abstract description 2
- 241000198596 Alternaria tomatophila Species 0.000 abstract 1
- 235000009849 Cucumis sativus Nutrition 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 29
- 239000003814 drug Substances 0.000 description 26
- 239000003795 chemical substances by application Substances 0.000 description 20
- -1 4-chlorophenoxy Chemical group 0.000 description 18
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- 230000003902 lesion Effects 0.000 description 18
- 241000196324 Embryophyta Species 0.000 description 13
- 238000000034 method Methods 0.000 description 11
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- 238000011282 treatment Methods 0.000 description 9
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- 239000002518 antifoaming agent Substances 0.000 description 7
- 239000010949 copper Substances 0.000 description 7
- 229910052802 copper Inorganic materials 0.000 description 7
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- 235000010493 xanthan gum Nutrition 0.000 description 6
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 5
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 5
- 150000002148 esters Chemical class 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 238000011835 investigation Methods 0.000 description 5
- 229910052710 silicon Inorganic materials 0.000 description 5
- 239000010703 silicon Substances 0.000 description 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical group CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000375 suspending agent Substances 0.000 description 4
- 238000010998 test method Methods 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- 241000233679 Peronosporaceae Species 0.000 description 3
- 231100000674 Phytotoxicity Toxicity 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
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- 238000003860 storage Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- JERZEQUMJNCPRJ-UHFFFAOYSA-N 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(C(F)(F)F)C=1C(O)(C)CN1C=NC=N1 JERZEQUMJNCPRJ-UHFFFAOYSA-N 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 description 2
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 2
- 239000013043 chemical agent Substances 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 239000003337 fertilizer Substances 0.000 description 2
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- 229920005646 polycarboxylate Polymers 0.000 description 2
- 150000003852 triazoles Chemical class 0.000 description 2
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 description 1
- CCLNWKPQPZBSEI-UHFFFAOYSA-N 2,3-diethoxypropan-1-ol Chemical compound CCOCC(CO)OCC CCLNWKPQPZBSEI-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 101710172072 Kexin Proteins 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 239000005811 Myclobutanil Substances 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 244000183278 Nephelium litchi Species 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- PCKPVGOLPKLUHR-UHFFFAOYSA-N OH-Indolxyl Natural products C1=CC=C2C(O)=CNC2=C1 PCKPVGOLPKLUHR-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
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- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 244000203593 Piper nigrum Species 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000005820 Prochloraz Substances 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- YKTSYUJCYHOUJP-UHFFFAOYSA-N [O--].[Al+3].[Al+3].[O-][Si]([O-])([O-])[O-] Chemical compound [O--].[Al+3].[Al+3].[O-][Si]([O-])([O-])[O-] YKTSYUJCYHOUJP-UHFFFAOYSA-N 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 229910000323 aluminium silicate Inorganic materials 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
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- 238000009835 boiling Methods 0.000 description 1
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 description 1
- 229920005551 calcium lignosulfonate Polymers 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 1
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
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- 230000015556 catabolic process Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- KYKAJFCTULSVSH-UHFFFAOYSA-N chloro(fluoro)methane Chemical compound F[C]Cl KYKAJFCTULSVSH-UHFFFAOYSA-N 0.000 description 1
- JLOULEJYJNBUMX-UHFFFAOYSA-L copper;quinoline-2-carboxylate Chemical compound [Cu+2].C1=CC=CC2=NC(C(=O)[O-])=CC=C21.C1=CC=CC2=NC(C(=O)[O-])=CC=C21 JLOULEJYJNBUMX-UHFFFAOYSA-L 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
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- 238000010520 demethylation reaction Methods 0.000 description 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 1
- MOTZDAYCYVMXPC-UHFFFAOYSA-N dodecyl hydrogen sulfate Chemical compound CCCCCCCCCCCCOS(O)(=O)=O MOTZDAYCYVMXPC-UHFFFAOYSA-N 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000003255 drug test Methods 0.000 description 1
- 230000002888 effect on disease Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 229910021485 fumed silica Inorganic materials 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- JYGFTBXVXVMTGB-UHFFFAOYSA-N indolin-2-one Chemical compound C1=CC=C2NC(=O)CC2=C1 JYGFTBXVXVMTGB-UHFFFAOYSA-N 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 235000019691 monocalcium phosphate Nutrition 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- LCRMGUFGEDUSOG-UHFFFAOYSA-N naphthalen-1-ylsulfonyloxymethyl naphthalene-1-sulfonate;sodium Chemical compound [Na].C1=CC=C2C(S(=O)(OCOS(=O)(=O)C=3C4=CC=CC=C4C=CC=3)=O)=CC=CC2=C1 LCRMGUFGEDUSOG-UHFFFAOYSA-N 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
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- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000000447 pesticide residue Substances 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 1
- 229910052939 potassium sulfate Inorganic materials 0.000 description 1
- 235000011151 potassium sulphates Nutrition 0.000 description 1
- TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 description 1
- 229930185107 quinolinone Natural products 0.000 description 1
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- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 1
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- 230000009885 systemic effect Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
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Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a pesticide composition containing oxine-copper and chlorofluoromethrin and application thereof, wherein the pesticide composition contains active ingredient chlorofluoromethrin and active ingredient oxine-copper, and the mass ratio of the two is 1-50. According to the application, the cloroxen-conazole and the oxine-copper are compounded, so that the cloroxen-conazole and the oxine-copper can generate a synergistic effect, and the formed pesticide bactericide has a good sterilization effect and has good activity on diseases such as potato diseases, early blight of tomatoes, target spot of cucumbers and the like; the action mechanisms of the effective components in the bactericidal composition are different from each other, so that the action sites of the effective components are increased, the prevention and control spectrum is expanded, the single selection pressure on pathogenic bacteria is reduced, the generation speed of the drug resistance of diseases is favorably delayed, the dosage is low, the cost is low, and meanwhile, the side effect of the bactericidal composition is low, and the safety, the yield and the like of crops are not influenced.
Description
Technical Field
The invention relates to the technical field of pesticides, and particularly relates to a pesticide bactericide composition containing clofafen and oxine-copper for preventing and treating diseases such as potato, tomato early blight, cucumber target spot and the like and application thereof.
Background
Early blight of potato (A) (Alternaria solani) Usually in the form of pathogenic spores in plant disease residues, seed potatoes or diseased soil. Pathogenic bacteria are spread by wind and rain, and invade from skin holes, stomata or injured parts of the potato leaves in the coming year to generate conidia, so that plants are infected with diseases; the potato early blight can damage plant leaves, petioles, stalks and tubers. Generally, when the potato is invaded by the early blight, the old lower leaves of the potato are infected first, and the disease can also damage new tender leaves until the potato growing period is about, so that a large number of leaves are withered and even die too early, and the yield of the potato is seriously damaged; in recent years, early blight can be seen in most potato planting areas in China, the damage degree is gradually increased, the yield of potatoes in China is greatly reduced, the quality of the potatoes is greatly reduced, and the production of the potatoes in China is greatly influenced.
The target spot of cucumber is due to the multiple major clavispora of Deuteromycotina (A)Corynespora cassiicola(Berk & Curt) Wei) causing fungiThe disease is reported for the first time in the last 60 th century in China, and because the disease is rare, the disease does not draw enough attention. In recent years, the growing scale of cucumber cultivation facilities is increasing, the disease is becoming more and more serious, and the disease becomes one of the main diseases in cucumber production; tomato early blight (C)Alternaria solani) The ring spot is also called as ring spot and is one of the important diseases of tomatoes, the ring spot occurs all over the country, generally starts to occur at the flowering stage or the initial stage of fruiting of the tomatoes, and damages leaves, leafstalks, stems and fruits of the tomatoes, thus causing fallen leaves, fallen flowers, fallen fruits, rotten fruits and broken branches and having serious influence on the growth of the tomatoes.
At present, diseases such as potato early blight, cucumber target spot disease, tomato early blight and the like are mainly prevented and controlled by chemical agents, but pesticide residues are easily caused by using a large amount of chemical agents, harm is caused to human health, and meanwhile, drug resistance is easily caused by long-term application of single chemical pesticide.
In view of the severity of three diseases and the harmfulness of chemical pesticides, the invention provides the aims of utilizing different action mechanisms of active ingredients in a combined compound, increasing action sites, enlarging a control spectrum, reducing single selection pressure on pathogenic bacteria, being beneficial to delaying the generation speed of disease resistance, having low dosage and low cost, and simultaneously having low side effect and not influencing the safety, the yield and the like of crops.
Chlorofloxacin (mefentrifluconazole) is the first triazole bactericide containing an isopropanol structure and has the chemical name of (2 RS) -2- [4- (4-chlorophenoxy) -alpha, alpha-trifluoro-o-tolyl]-1- (1H-1, 2, 4-triazol-1-yl) propan-2-ol having CAS number 1417782-03-6 and molecular formula C 18 H 15 ClF 3 N 3 O 2 The relative molecular mass is 397.8, and the molecular structural formula of the chlorofluoromethane is shown as formula 1. The chlorofluoromethane can be dissolved in water and an organic solvent, the solubility of the chlorofluoromethane in water is 0.81mg/L at the temperature of 20 ℃, the water solubility is lower, the volatility is lower, and the chlorofluoromethane cannot enter underground water through leaching; the solubilities in organic solvents of acetone, ethyl acetate, xylene and 1, 2-dichloroethane were 93.2, 116.2, 8.5 and 55.3mg/L, respectively. Chlorofloxacin has a melting point of 1The degradation point is 300 ℃ at 26 ℃, and the material can be decomposed in a boiling state but is not easy to burn.
The chlorofluoromethane is a novel isopropyl alcohol triazole bactericide which has broad spectrum, high efficiency and systemic effect and has the functions of eradicating and protecting, and belongs to sterol demethylation inhibitors. Different from the widely used triazole bactericide, the chlorofluoromethane contains an isopropanol structure, so that the mutation of pathogenic bacteria can be reduced, and the drug resistance of the pathogenic bacteria can be delayed.
The oxine-copper is a broad-spectrum, high-efficiency and low-toxicity chelated organic copper bactericide, has excellent prevention and treatment effects on crop fungi and bacterial diseases, has double bactericidal effects of the organic quinoline and the copper bactericide, has multiple target sites, is not easy to generate resistance to germs after multiple use, is high-efficiency on resistant strains of conventional bactericides, and has long medicament duration. In the prior production, the oxine-copper is mainly applied to preventing and treating bacterial or fungal diseases such as tomato early blight, bacterial canker, pepper phytophthora blight, canker, scab, downy mildew, cucumber target spot and bacterial leaf spot, downy mildew of litchi, watermelon downy mildew, anthracnose, bacterial fruit spot, potato early blight and the like.
Because the prevention and control difficulty of potato, tomato early blight and cucumber target spot disease is high, the harm is serious, the commonly used prevention and control medicaments such as prochloraz and the like are old medicaments with long time and high resistance, and the prevention and control effect is poor, in the published report, the activities of the clofaflurazole and the oxine-copper on the potato, the tomato early blight and the cucumber target spot disease are not deeply researched, and the compounding of the clofaflurazole and the oxine-copper is not reported at present. Therefore, in the prior art, different medicaments are combined to control diseases, but the effect of the combination of different medicaments is uncertain, and the combination of different medicaments can produce synergistic effect and antagonistic effect. And the effect of combinations of different agents on different diseases is uncertain.
Disclosure of Invention
In order to solve the technical problems in the background art, the application provides a pesticide bactericide containing chlorofluoromethane and oxine-copper for preventing and treating diseases such as potato, tomato early blight, cucumber target spot and the like.
The purpose of the invention is realized by the following technical scheme:
the pesticide bactericide containing the meperflutonazole and the oxine-copper comprises the active ingredients of the meperflutonazole and the oxine-copper, and is characterized in that: the mass ratio of the chlorofluoroether azole to the oxine-copper is 1 to 50 to 1.
The mass of the chlorofluoromethrin accounts for 1-40% of that of the pesticide bactericide; the mass of the oxine-copper accounts for 1-45% of the mass of the pesticide bactericide.
As a preferable technical solution, the method is characterized in that: the mass of the chlorofluoromethrin accounts for 10% of that of the pesticide bactericide; the mass of the oxine-copper accounts for 30% of that of the pesticide bactericide.
As a preferable technical solution, the method is characterized in that: the bactericidal composition further comprises the following substances in percentage by mass: 1 to 9 percent of dispersant, 3 to 5 percent of wetting agent, 0.1 to 2.5 percent of thickening agent, 0.1 to 4 percent of preservative, 1 to 8 percent of antifreezing agent and the balance of water.
Compared with the prior art, the invention has the following beneficial effects:
in the published reports, the activities of the chlorofluoromethane and the oxine-copper on diseases such as potato, tomato early blight, cucumber target spot and the like are not deeply researched, and the compounding of the chlorofluoromethane and the oxine-copper is not reported at present. The bactericide composition containing the chlorofluoroethaneconazole and the oxine-copper is compounded, has obvious synergistic effect, can effectively improve the control effect on diseases such as potato, tomato early blight, cucumber target spot and the like, can reduce the using dosage of active ingredients, reduces the production cost and reduces the environmental pollution.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
The embodiment of the invention provides a pesticide bactericide, wherein the raw materials of active ingredients of the pesticide bactericide comprise chlorofluoromethane and oxine-copper. The embodiment of the invention specifically selects the chlorofluoromethane and the oxine-copper for compounding, and the chlorofluoromethane and the oxine-copper can generate synergistic action, so that the formed pesticide bactericide has good bactericidal effect and a large control spectrum, and particularly has good control effect on potato early blight and cucumber target spot.
The components in the embodiment of the invention are as follows:
the wetting and dispersing agent can be one or two selected from TERSPERSE 4894, TERSPERSE 2500, phosphate ester type anionic surfactant, polyoxyethylene type nonionic surfactant, alkylphenol polyoxyethylene phosphate, fatty acid polyoxyethylene ether, alkyl naphthalene sulfonate mixture, polycarboxylate, alkyl naphthalene sulfonate mixture, sodium methylene dinaphthalene sulfonate, lauryl sulfuric acid, sodium, phosphate potassium salt, calcium lignosulfonate, ammonium sulfate, polysulfate, polycarboxylate, calcium dodecylbenzene sulfonate, nekal BX, alkylphenol polyoxyethylene ether, alkylphenol formaldehyde resin polyoxyethylene ether and TERSPERSE 2280;
the thickener may be selected from any one or more of xanthan gum, carboxymethyl cellulose, sodium polyacrylate, magnesium aluminium silicate, fumed silica or attapulgite.
The antifreezing agent can be one or more of ethylene glycol, propylene glycol, glycerol-diethyl ether diglycol or methyl propylene diglycol according to any proportion;
the stabilizer may be any one or more selected from 2, 6-di-tert-butyl-4-methylphenol (BHT), citric acid or Butyl Hydroxyanisole (BHA).
The preservative may be sodium benzoate.
The bactericide provided by the invention is used for preventing and treating diseases of crops including but not limited to potato, tomato early blight and cucumber target spot, and the pesticide bactericide has better effect on preventing and treating the potato, tomato early blight and cucumber target spot. In addition, the pesticide bactericide can not influence the normal growth of plants. The pesticide bactericide is a liquid preparation, preferably a suspending agent, and it should be noted that the embodiment of the invention only exemplifies the suspending agent, but it is understood that other types of liquid preparations are also within the scope of the embodiment of the invention.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment of the invention provides a bactericidal composition, the effective components of which are respectively meperflutonazole and oxine-copper, and the mass ratio of the meperflutonazole to the oxine-copper is 10.
Example 2
The embodiment of the invention provides a bactericidal composition, the effective components of which are respectively meperflutonazole and oxine-copper, and the mass ratio of the meperflutonazole to the oxine-copper is 10.
Example 3
The embodiment of the invention provides a bactericidal composition, the effective components of which are respectively meperflutonazole and oxine-copper, and the mass ratio of the meperflutonazole to the oxine-copper is 10.
Example 4
The embodiment of the invention provides a bactericidal composition, the effective components of which are respectively meperflutonazole and oxine-copper, and the mass ratio of the meperflutonazole to the oxine-copper is 10.
Example 5
The embodiment of the invention provides a sterilization composition, which comprises the effective components of chlorofluoromethane and oxine-copper, wherein the mass ratio of the chlorofluoromethane to the oxine-copper is 10.
Example 6
The embodiment provides a bactericidal composition, which comprises the following components in percentage by mass:
TABLE 1 fungicidal compositions
| Name of ingredient | Content (%) |
| Chlorofloxacin hydrochloride | 10 |
| Quinolinic copper | 5 |
| Alkyl phenol polyoxyethylene phosphate ester | 3 |
| Fatty acid polyoxyethylene ether | 1 |
| Xanthan gum | 0.2 |
| Magnesium aluminum silicate | 1.6 |
| Sodium benzoate | 0.5 |
| Ethylene glycol | 4 |
| Organic silicon defoaming agent | 0.2 |
| Water (W) | Make up the surplus |
Example 7
The embodiment provides a bactericidal composition, which comprises the following components in percentage by mass:
TABLE 2 dosage ratio of each component in the bactericidal composition
| Name of ingredient | Content (%) |
| Chlorofloxacin (CFR) azole | 10 |
| Quinolinic copper | 10 |
| Alkyl phenol polyoxyethylene phosphate ester | 4 |
| Fatty acid polyoxyethylene ether | 2 |
| Xanthan gum | 0.15 |
| Magnesium aluminum silicate | 2 |
| Sodium benzoate | 0.5 |
| Ethylene glycol | 4 |
| Organic silicon defoaming agent | 0.2 |
| Water (W) | Make up the surplus |
Example 8
The embodiment provides a bactericidal composition, which comprises the following components in percentage by mass:
TABLE 3 the ratio of the components in the bactericidal composition
| Name of ingredient | Content (%) |
| Chlorofloxacin hydrochloride | 10 |
| Quinolinic copper | 15 |
| Alkyl phenol polyoxyethylene phosphate ester | 4 |
| Fatty acid polyoxyethylene ether | 2.5 |
| Xanthan gum | 0.2 |
| Magnesium aluminum silicate | 1.7 |
| Sodium benzoate | 0.6 |
| Ethylene glycol | 4 |
| Organic silicon defoaming agent | 0.2 |
| Water (W) | Make up the balance |
Example 9
The embodiment provides a sterilization composition, which comprises the following components in percentage by mass:
TABLE 4 composition of bactericidal composition
| Name of ingredient | Content (%) |
| Chlorofloxacin hydrochloride | 10 |
| Quinolinic copper | 20 |
| Alkyl phenol polyoxyethylene phosphate ester | 4.5 |
| Fatty acid polyoxyethylene ether | 3 |
| Xanthan gum | 0.2 |
| Magnesium aluminum silicate | 1.2 |
| Sodium benzoate | 0.5 |
| Ethylene glycol | 4.5 |
| Organic silicon defoaming agent | 0.2 |
| Water (W) | Make up the balance |
Example 10
The embodiment provides a bactericidal composition, which comprises the following components in percentage by mass:
TABLE 5 composition of the composition
| Names of ingredients | Content (%) |
| Chlorofloxacin (CFR) azole | 10 |
| Quinolinic copper | 30 |
| Alkyl phenol polyoxyethylene phosphate ester | 5 |
| Fatty acid polyoxyethylene ether | 4 |
| Xanthan gum | 0.15 |
| Magnesium aluminum silicate | 0.5 |
| Sodium benzoate | 0.6 |
| Ethylene glycol | 4.5 |
| Organic silicon defoaming agent | 0.2 |
| Water (W) | Make up the balance |
The invention provides a method for preparing the pesticide composition into a pesticide suspending agent, which comprises the following steps: the copper quinolate and the chlorofluroxypyr are mixed with a wetting agent, a dispersing agent, an antifreezing agent, a preservative, part of a thickening agent (50-70% of the total mass), part of a defoaming agent (50-70% of the total mass), water and the like to be uniformly ground, when the particle size is 4 mu m, the grinding is stopped, and the rest thickening agent and the defoaming agent are added to be uniformly regulated to prepare the suspending agent.
Experimental example 1 biological Activity test
According to the indoor bioassay test criteria NY/T1156.2-2006 and NY/T1156.6-2006 of the pesticide, the optimal mixing mass ratio of the two bactericides is screened by determining the effect of the chlorofluoromethane and oxine-copper on the potato early blight by mixing the chlorofluoromethane and the oxine-copper according to different mass ratios.
A. Early blight of potato (A) (Alternaria solani) Provided by the plant pathology laboratory of Qingdao agricultural university.
B. The test agents were 97% chlorofluoromethane technical (from Pasteur Europe), 98% oxine-copper technical (from Xinglong agriculture Co., ltd.)
C. Chlorofloxacin: the mixing ratio of the oxine-copper is as follows: 4:
TABLE 6 dosage ratio of each substance of the bactericidal composition
D. Virulence test method
Activating the preserved potato early blight bacteria, culturing at 25 deg.C in dark for 5 days, punching hypha blocks with diameter of 5mm from the edge of the cultured colony with sterilized puncher, transferring onto flat culture medium with medicine, and repeating for 3 times. Culturing in a constant temperature incubator at 25 ℃, measuring the diameter of the colony by adopting a cross method when the diameter of the contrast colony is about 2/3 of the diameter of the culture dish, and calculating the average value of the diameter of the colony and the hypha growth inhibition rate. The average bacteriostasis rate of 3 repetitions is converted into a few values, the medicament concentration is converted into a logarithmic value, and the virulence index, the cotoxicity coefficient and the like of each medicament are calculated according to the Sun cloud Peel method.
Using DPS statistical software to carry out regression analysis on the treatment concentration logarithmic value and the corresponding inhibition rate probability value of each single agent and the mixed combination with different proportions, and calculating a toxicity regression curve and EC 50 Value, correlation coefficient, and calculating co-toxicity coefficient (CTC value) of the mixture according to Sun cloud Peel method.
The co-toxicity coefficient (CTC value) of the mixture is calculated according to the formula (1), the formula (2) and the formula (3):
in the formula:ATI-measured virulence index of the mixture;
SEC of standard fungicides 50 In milligrams per liter (mg/L);
MEC of admixtures 50 In milligrams per liter (mg/L).
In the formula:TTI-the theoretical virulence index of the cocktail;
A-a agent virulence index;
P A the percentage of the agent A in the mixture is in percentage (%);
B-B agent virulence index;
P B the percentage of the B agent in the mixture is in percentage (%).
In the formula: CTC-co-toxicity coefficient; ATI-measured toxicity index of mixed agent; TTI-theoretical virulence index of the mixture.
The co-toxicity coefficient (CTC) of the compound combination is more than or equal to 120, which shows a synergistic effect; CTC is less than or equal to 80 and shows antagonism; 80 < CTC < 120 showed additive effects.
E. Test results tables 7 and 8:
TABLE 7 toxicity test results of CFR, quinolinone and 7 ratios
TABLE 8 measurement results of combined toxicity of CFR (chlorofluorocarbon Ether-myclobutanil) and oxine-copper mixture on potato early blight
Studies have shown (table 8) that effective inhibition of potato early blight by 7 formulated combinations (chlorofluroxypyr: oxindole =4:1, 3, 1,2, 1, 3, 1, 4) at concentrations of 0.7838, 0.8534, 0.9618, 1.2368, 1.5792, 1.9501 and 2.4948mg/L, respectively, and a co-toxicity coefficient (CTC) of 133.28
129.34, 126.71, 124.45, 132.25, 130.35, 117.15, it can be seen that the ratios of chlorofluoromethane and oxine-copper are 4, 1,2, 1.
Experimental example 2 field drug effect test
The first field pesticide effect test: the bactericidal composition prepared in the application example 10 is used for preventing and controlling early blight of potatoes in fields.
1. Test method
The test agents are shown in table 9 below:
TABLE 9 Scale for each drug test
Guo Jia Zhuang village (northern latitude 36.433217, east longitude 120.4822) in Jimo area of Qingdao city. The test field area is 2 mu, the pH value of the soil is 6.4, and the organic matter content is 1.8%. The test crop is potato, kexin No. 1, and the row spacing of the plants is 60 multiplied by 20cm. Early blight of potatoes occurs in nearly three years, and the early blight of potatoes is prevented and controlled by the pesticide every year. The soil type is yellow cotton soil, the pH value is neutral, 1000kg of farmyard manure, 40kg of urea, 25kg of common calcium superphosphate and 30kg of potassium sulfate are applied to each mu of land, watering is carried out for 1 time, and the management level is general. And (5) sowing the potatoes in summer. All the test plots have the same cultivar and the same management condition, and the test target is potato early blight. The application method is that the conventional spraying method is used for applying the pesticide for the 1 st time at the early stage of the potato early blight (7 months and 5 days), the pesticide for the 2 nd time is applied at intervals of 7 days and 7 months and 12 days, and the pesticide is applied for 2 times in the test.
The liquid medicine is sprayed by a common pressure storage type manual sprayer (commercially available), a conical nozzle can be adjusted, the pressure is 0.3MPa, the spraying speed is 0.6 liter/min, and the liquid medicine usage amount per hectare is 600 liters; the method comprises the following steps of field investigation of the incidence condition of potato early blight before the first pesticide application, investigation 7 days after the last pesticide application, sampling 5 points in each plot, investigating 3 plants in each plot, investigating all leaves in each plant, and dividing disease grades according to the percentage of lesion areas on the leaves to the whole leaf area:
the classification criteria were as follows:
level 0: no disease spots;
level 1: the lesion area accounts for less than 5% of the whole leaf area;
and 3, level: the lesion area accounts for 6 to 10 percent of the whole leaf area;
stage 5: the lesion area accounts for 11% -20% of the whole leaf area;
and 7, stage: the lesion area accounts for 21-50% of the whole leaf area;
and 9, stage: the lesion area accounts for more than 51 percent of the whole leaf area;
2. test results
The control effect of different medicament treatments on potato early blight is shown in table 10 below.
TABLE 10 prevention and treatment of early blight of potato with different agents
According to the table, the results of the control effect survey show that in example 10, the control effect is the best when the dosage of the preparation is 60 ml/mu, the control effect is 85.80%, and the control effect is remarkably superior to that of two single-dose control medicaments. Through field observation, the test agent and the control agent are safe to test crop potatoes, and no phytotoxicity symptoms (such as dwarfing, chlorosis, deformity and the like) are found.
And (2) field efficacy test II: the bactericidal composition prepared in the application example 10 is used for preventing and controlling cucumber target spot in the field.
1. Test method
The test agents are shown in table 11 below:
TABLE 11 Scale for testing each drug
The method comprises the steps of carrying out 1 st pesticide application in the early stage of the target spot disease of the cucumber (5 month and 28 days), carrying out 7 days and 2 nd pesticide application in 6 months and 4 days in 6 months in the conventional spraying method, wherein the 1 st pesticide application is carried out in the conventional spraying method in the initial stage of the target spot disease of the cucumber (5 month and 28 days), and the 2 nd pesticide application is carried out in the conventional spraying method, and the experiments are carried out for 2 times in total.
The liquid medicine is sprayed by a common pressure storage type manual sprayer (commercially available), a conical nozzle can be adjusted, the pressure is 0.3MPa, the spraying speed is 0.6 liter/minute, and the liquid medicine usage amount per hectare is 750 liters; the disease condition of cucumber target spot disease is investigated in field before the first pesticide application, the investigation is carried out 7 days after the last pesticide application, 5 surveys are randomly taken from each plot, 5 plants are investigated from each plot, all leaves are investigated from each plant, the total leaf number and the leaf number of each stage of disease in the investigation are recorded, and the disease stage is divided according to the percentage of the area of the disease spot on each leaf in the whole leaf area:
the classification criteria are as follows:
level 0: no lesion spots;
stage 1: the lesion area accounts for less than 5% of the whole leaf area;
and 3, level: the lesion spot area accounts for 6-10% of the whole leaf area;
stage 5: the lesion area accounts for 11% -20% of the whole leaf area;
and 7, stage: the lesion area accounts for 21-40% of the whole leaf area;
and 9, stage: the lesion spot area accounts for more than 40% of the whole leaf area;
2. test results
The control effect of different medicament treatments on cucumber target spot disease is shown in table 12 below.
TABLE 12 prevention and treatment effects of different agents on cucumber target spot
According to the table, the results of the control effect survey show that in example 10, the control effect is the best when the dosage of the preparation is 60 mL/mu, the control effect is 87.12%, and the control effect is remarkably superior to that of two single-dose control medicaments. Through field observation, the tested medicament and the control medicament are safe to cucumber serving as a test crop, and no phytotoxicity symptoms (such as dwarfing, chlorosis, deformity and the like) are found.
And (3) field efficacy test: the bactericidal composition prepared in the application example 10 is used for preventing and controlling tomato early blight in fields.
1. Test method
The test agents are shown in Table 13 below
TABLE 13 Scale for testing each drug
The Kao Jiazhuang village (36.467832 north latitude, 120.4412 east longitude, 2 mu of test field area, 6.4 soil pH value and 1.8% organic matter content) in the Jimo area of Qingdao city, wherein the test crops are tomatoes, chaoqiang, 11-day seedlings at 06 and 11 days of 2021 year, 03-day soil preparation at 07 and 03 days of 2021 year, 30kg of compound fertilizer (15-15-15) is used as base fertilizer per mu, and the Kao Jiazhuang village is artificially transplanted at 07 and 05 days of 2021 year, wherein 3000 plants per mu, the plant spacing is 30cm, and the row spacing is 50cm.
The cultivation management conditions meet the local agricultural production practice. The test target is tomato early blight. The application method is that the conventional spraying method is used for applying the first time at the initial stage (8 months and 10 days) of the tomato early blight, applying the second time at intervals of 7 days and 8 months and 17 days, and the application time of the test is 2 times.
The liquid medicine is sprayed by a common pressure storage type manual sprayer (commercially available), a conical spray head can be adjusted, the pressure is 0.3MPa, the spraying speed is 0.6 liter/minute, and the liquid medicine usage amount per hectare is 600 liters; the method comprises the following steps of investigating the tomato early blight on site in the field before the first pesticide application, investigating 7 days after the last pesticide application, randomly taking 5 points for each district, investigating 2 plants at each point, investigating 10 leaves at each plant, recording the total leaf number and the leaf number of each stage of disease in the investigation, and dividing the disease stage according to the percentage of the lesion area on each leaf in the whole leaf area:
the classification criteria are as follows:
stage 0: no disease spots;
level 1: the lesion area accounts for less than 5% of the whole leaf area;
and 3, stage: the lesion area accounts for 6 to 10 percent of the whole leaf area;
stage 5: the lesion spot area accounts for 11-20% of the whole leaf area;
and 7, stage: the lesion area accounts for 21-50% of the whole leaf area;
and 9, stage: the lesion area accounts for more than 51 percent of the whole leaf area;
2. test results
The control effect of different medicament treatments on tomato early blight is shown in table 14 below.
TABLE 14 prevention and treatment of tomato early blight by different drug treatments
According to the table, the results of the control effect survey show that in example 10, the control effect is the best when the dosage of the preparation is 60 mL/mu, the control effect is 87.41%, and the control effect is remarkably superior to that of two single-dose control medicaments. Through field observation, the test agent and the control agent are safe to test crops, namely tomatoes, and no phytotoxicity symptoms (such as dwarfing, chlorosis, deformity and the like) are found.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (6)
1. A pesticide bactericide containing chlorofluoroether oxazole and oxine-copper is characterized in that: the pesticide bactericide is used for preventing and treating diseases such as potato, tomato early blight, cucumber target spot and the like.
2. The pesticidal fungicide containing clobetasol and oxine-copper according to claim 1, characterized in that: the mass ratio of the chlorofluoroether azole to the oxine-copper is 1 to 50 to 1.
3. The pesticidal fungicide containing clobetasol and oxine-copper according to claim 1, characterized in that: the mass of the chlorofluoromethrin accounts for 1-40% of that of the pesticide bactericide; the mass of the oxine-copper accounts for 1-45% of that of the pesticide bactericide.
4. The pesticidal fungicide containing clobetasol and oxine-copper according to claim 1, characterized in that: the mass of the chlorofluoromethrin accounts for 10% of that of the pesticide bactericide; the mass of the oxine-copper accounts for 30% of that of the pesticide bactericide.
5. The bactericidal composition containing meperflutonazol and oxine-copper according to any one of claims 1 to 4, wherein: the dosage form of the sterilization composition is a liquid preparation.
6. The bactericidal composition containing cloflufen-azole and oxine-copper according to claim 5, wherein: the bactericidal composition further comprises the following substances in percentage by mass: 1 to 9 percent of dispersant, 3 to 5 percent of wetting agent, 0.1 to 2.5 percent of thickening agent, 0.1 to 4 percent of preservative, 1 to 8 percent of antifreeze and the balance of water.
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| CN105050406A (en) * | 2012-12-20 | 2015-11-11 | 巴斯夫农业公司 | Compositions comprising a triazole compound |
| CN111988995A (en) * | 2018-03-26 | 2020-11-24 | Upl有限公司 | Fungicidal combinations |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105050406A (en) * | 2012-12-20 | 2015-11-11 | 巴斯夫农业公司 | Compositions comprising a triazole compound |
| CN111988995A (en) * | 2018-03-26 | 2020-11-24 | Upl有限公司 | Fungicidal combinations |
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| Title |
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| DISCLOSED ANONYMOUSLY: "Use of pesticidal compositions comprising mefentrifluconazole", pages: 252 - 258 * |
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