CN115942944A - 使用颤螺旋菌科微生物胞外囊泡治疗疾病和障碍的组合物和方法 - Google Patents

使用颤螺旋菌科微生物胞外囊泡治疗疾病和障碍的组合物和方法 Download PDF

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Publication number
CN115942944A
CN115942944A CN202180042020.3A CN202180042020A CN115942944A CN 115942944 A CN115942944 A CN 115942944A CN 202180042020 A CN202180042020 A CN 202180042020A CN 115942944 A CN115942944 A CN 115942944A
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pharmaceutical composition
mev
strain
cancer
smev
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Pending
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CN202180042020.3A
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English (en)
Chinese (zh)
Inventor
A·巴洛克
L·弗朗西斯科-安德森
M·西佐娃
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Epiva Biosciences Inc
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Epiva Biosciences Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
CN202180042020.3A 2020-06-11 2021-06-11 使用颤螺旋菌科微生物胞外囊泡治疗疾病和障碍的组合物和方法 Pending CN115942944A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063037771P 2020-06-11 2020-06-11
US63/037771 2020-06-11
PCT/US2021/036978 WO2021252877A1 (en) 2020-06-11 2021-06-11 Compositions and methods for treating diseases and disorders using oscillospiraceae microbial extracellular vesicles

Publications (1)

Publication Number Publication Date
CN115942944A true CN115942944A (zh) 2023-04-07

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180042020.3A Pending CN115942944A (zh) 2020-06-11 2021-06-11 使用颤螺旋菌科微生物胞外囊泡治疗疾病和障碍的组合物和方法

Country Status (13)

Country Link
US (1) US20230263838A1 (pt)
EP (1) EP4164664A1 (pt)
JP (1) JP2023530413A (pt)
KR (1) KR20230038476A (pt)
CN (1) CN115942944A (pt)
AR (1) AR122610A1 (pt)
AU (1) AU2021287978A1 (pt)
BR (1) BR112022025128A2 (pt)
CA (1) CA3180044A1 (pt)
CO (1) CO2023000114A2 (pt)
MX (1) MX2022015630A (pt)
TW (1) TW202214274A (pt)
WO (1) WO2021252877A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240131083A1 (en) * 2020-12-22 2024-04-25 Evelo Biosciences, Inc. Compositions comprising animal hemoglobin
WO2023158204A1 (en) * 2022-02-15 2023-08-24 Enterobiome Inc. Pharmaceutical composition for preventing or treating cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101833502B1 (ko) * 2016-12-16 2018-03-05 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 위암 진단방법
KR101833504B1 (ko) * 2016-12-26 2018-03-05 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 폐암 진단방법
JP7369690B2 (ja) * 2017-09-08 2023-10-26 エヴェロ バイオサイエンシズ，インコーポレーテッド 細菌の細胞外小胞
US10493113B2 (en) * 2017-11-14 2019-12-03 Evelo Biosciences, Inc. Compositions and methods for treating disease using a Blautia strain
WO2019152667A1 (en) * 2018-01-31 2019-08-08 Evelo Biosciences, Inc. Compositions and methods for treating immune disorders using lachnospiraceae bacteria
WO2021146523A1 (en) * 2020-01-17 2021-07-22 Evelo Biosciences, Inc. Solid dosage forms with improved disintegration profiles

Also Published As

Publication number Publication date
JP2023530413A (ja) 2023-07-18
TW202214274A (zh) 2022-04-16
KR20230038476A (ko) 2023-03-20
EP4164664A1 (en) 2023-04-19
AU2021287978A1 (en) 2023-02-02
CA3180044A1 (en) 2021-12-16
WO2021252877A1 (en) 2021-12-16
AR122610A1 (es) 2022-09-21
CO2023000114A2 (es) 2023-01-16
MX2022015630A (es) 2023-01-11
BR112022025128A2 (pt) 2023-01-17
US20230263838A1 (en) 2023-08-24

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