CN115919941A - Medicine for regulating intestinal flora by using citrus reticulata blanco extract as main component and preparation method - Google Patents

Medicine for regulating intestinal flora by using citrus reticulata blanco extract as main component and preparation method Download PDF

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Publication number
CN115919941A
CN115919941A CN202310017937.9A CN202310017937A CN115919941A CN 115919941 A CN115919941 A CN 115919941A CN 202310017937 A CN202310017937 A CN 202310017937A CN 115919941 A CN115919941 A CN 115919941A
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parts
extract
medicine
hawthorn
intestinal flora
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高海峰
叶兴乾
陈健乐
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Hangzhou Joyful Biotechnology Co ltd
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Hangzhou Joyful Biotechnology Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention discloses a medicine for regulating intestinal flora by taking an orange collaterals extract as a main component, which comprises the following components in parts by weight: 15-20 parts of tangerine pith extract, 4-6 parts of codonopsis pilosula, 3-4 parts of bighead atractylodes rhizome, 4-5 parts of kudzuvine root, 5-8 parts of astragalus membranaceus, 2-3 parts of hawthorn, 4-6 parts of cinnamon, 3-4 parts of liquorice, 4-6 parts of hericium erinaceus and 3-4 parts of honey. The preparation method comprises the following steps of taking traditional Chinese medicinal materials in corresponding parts: steaming 4 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 4 parts of kudzuvine root, 6 parts of astragalus root, 4 parts of cinnamon, 3 parts of liquorice and 4 parts of hericium erinaceus for 30 minutes by using steam, and putting the steamed products into a stirring machine for stirring; putting the crushed Chinese medicinal materials into a heating kettle, sequentially adding purified water, decocting with strong fire for 20 minutes, and slowly decocting with slow fire for 60-80 minutes; after the decoction is finished, the mixture is cooled and kept stand for 2 to 3 hours in an environment with the temperature of 4 ℃, and the traditional Chinese medicine residues are filtered; peeling and removing kernels of hawthorn, drying in the sun, and grinding into powder for later use; adding micromolecular pectin, citrus flavone, hawthorn powder and honey into the liquid medicine, and uniformly stirring.

Description

Medicine for regulating intestinal flora by using citrus reticulata blanco extract as main component and preparation method
Technical Field
The invention relates to the technical field of application of citrus reticulata extract, in particular to a medicine for regulating intestinal flora by taking the citrus reticulata extract as a main component and a preparation method thereof.
Background
The tangerine pith, also called tangerine peel and tangerine tendon, is the tendon and the channel in the fruit peel of citrus of Rutaceae, and the traditional Chinese medical science believes that the tangerine pith has the functions of dredging channels, reducing phlegm, guiding qi downward, activating blood circulation and resisting cancer, and meanwhile, the tangerine pith is not only a good food therapy product for patients with chronic diseases such as chronic bronchitis, coronary heart disease and the like, but also has an auxiliary treatment effect on uncomfortable chest and hypochondrium pain caused by chronic cough; modern nutriology researches believe that the tangerine pith contains a substance called rutin, and the rutin can keep normal elasticity and compactness of blood vessels, reduce brittleness and permeability of blood vessel walls and has the effects of preventing cerebral hemorrhage of hypertension patients and retinal hemorrhage of diabetes patients. For people who have a tendency to bleed at ordinary times, especially the old people who have a tendency to angiosclerosis, eating the tangerine pith is more beneficial and harmless.
Researches also find that the tangerine pith and the tangerine pith extract can promote and improve the original drug effect of the Chinese herbal medicine, reduce the generation of side effects of the Chinese herbal medicine, lead the drug effect to tend to be mild and shorten the treatment effect when being combined with other Chinese herbal medicines.
The application is directed to patients with intestinal function and intestinal flora disorders.
Disclosure of Invention
The invention provides a medicine for regulating intestinal flora by taking an orange collaterals extract as a main component and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical means:
a medicine for regulating intestinal flora mainly comprises Mandarin orange collaterals extract,
the medicine comprises the following components in parts by weight: 15-20 parts of tangerine pith extract, 4-6 parts of codonopsis pilosula, 3-4 parts of bighead atractylodes rhizome, 4-5 parts of kudzuvine root, 5-8 parts of astragalus, 2-3 parts of hawthorn, 4-6 parts of cinnamon, 3-4 parts of liquorice, 4-6 parts of hericium erinaceus, 3-4 parts of honey and 15-20 parts of purified water;
the tangerine pith extract is composed of micromolecular pectin and citrus flavone prepared by physically separating the extract of the citrus fiber concentrated solution formed after squeezing and filtering
Preferably, the first and second liquid crystal materials are,
the medicine comprises the following components in parts by weight: 15 parts of tangerine pith extract, 4 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 4 parts of kudzu root, 6 parts of astragalus membranaceus, 2 parts of hawthorn, 4 parts of cinnamon, 3 parts of liquorice, 4 parts of hericium erinaceus, 3 parts of honey and 15 parts of purified water.
Preferably, the first and second liquid crystal materials are,
the preparation comprises the following medicinal components in parts by weight: 20 parts of tangerine pith extract, 6 parts of codonopsis pilosula, 4 parts of bighead atractylodes rhizome, 5 parts of kudzu root, 8 parts of astragalus membranaceus, 3 parts of hawthorn, 6 parts of cinnamon, 4 parts of liquorice, 6 parts of hericium erinaceus, 4 parts of honey and 20 parts of purified water.
In a preferred embodiment of the method of the invention,
the optimal mixture ratio of the medicine components and the parts is as follows: 18 parts of tangerine pith extract, 5 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 5 parts of kudzu root, 6 parts of astragalus membranaceus, 3 parts of hawthorn, 5 parts of cinnamon, 4 parts of liquorice, 5 parts of hericium erinaceus, 3 parts of honey and 20 parts of purified water.
A preparation method of a medicine for regulating intestinal flora by taking an orange collaterals extract as a main material,
taking traditional Chinese medicinal materials in corresponding parts: steaming 4 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 4 parts of kudzuvine root, 6 parts of astragalus root, 4 parts of cinnamon, 3 parts of liquorice and 4 parts of hericium erinaceus for 30 minutes by using steam, naturally cooling, and putting into a pulper for crushing;
step two, putting the crushed Chinese medicinal materials into a heating kettle, sequentially adding purified water, decocting for 20 minutes with strong fire, and then slowly decocting for 60-80 minutes with slow fire;
step three, after the decoction is finished, the decoction is refrigerated and kept stand for 2 to 3 hours in an environment with the temperature of 4 ℃, and the traditional Chinese medicine residues are filtered for later use;
step four, removing peel and kernels of hawthorn, drying in the sun, and grinding into powder for later use;
and step five, sequentially adding the tangerine pith extract, the hawthorn powder and the honey into the filtered liquid medicine, uniformly stirring, and sealing for storage.
Preferably, the first and second liquid crystal materials are,
the dregs obtained by filtering in the third step can be externally applied to navel for use.
The pharmacological action of each component is as follows:
the codonopsis pilosula has the effects of tonifying middle-jiao and Qi, harmonizing stomach and promoting fluid production and weakness of spleen and stomach;
the bighead atractylodes rhizome has the effects of tonifying spleen and stomach, eliminating dampness and promoting diuresis, and is used for treating weakness of spleen and stomach;
radix Puerariae has effects in expelling pathogenic factors from muscles, relieving fever, promoting eruption, promoting salivation, quenching thirst, invigorating yang, and relieving diarrhea;
astragalus root, radix astragali, benefiting vital qi, strengthening spleen and stomach, discharging pus and relieving pain;
hawthorn, fructus crataegi, for resolving food stagnation and dissipating blood stasis;
cinnamon has the functions of warming the middle-jiao and tonifying the kidney, and dispelling cold and relieving pain, and is used for treating cold pain of waist and knees, deficiency cold stomachache, chronic dyspepsia, abdominal pain, vomiting and diarrhea;
licorice root, used for deficiency-cold of spleen and stomach, peptic ulcer, poisoning;
hericium erinaceus is beneficial to five internal organs and helps digestion.
The medicine for conditioning intestinal flora mainly by using the citrus reticulata blanco extract and the preparation method have the beneficial effects that:
through various traditional Chinese medicinal materials with mild temperament, the tangerine pith extract and beneficial substances contained in the tangerine pith extract, the side effects of the original traditional Chinese medicine can be improved, the drug effect of the traditional Chinese medicine is improved, the honey and the hawthorn are added, the taste of the traditional Chinese medicine can be improved, the traditional Chinese medicine is convenient to take regularly and quantitatively, the functions of a gastrointestinal system can be greatly improved, and the intestinal flora can be recuperated;
meanwhile, the preparation is convenient, the storage is convenient, the batch preparation is suitable, the carrying and the use are convenient, and the taking and the use are convenient;
the medicine liquid is taken orally, and the medicine dregs are externally applied, so that the treatment effect is better while the utilization rate of the medicinal materials is improved.
Detailed Description
The technical solutions of the present invention will be described clearly and completely below, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate orientations or positional relationships based on the illustrated orientations or positional relationships, and are only used for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in a specific case to those of ordinary skill in the art.
A medicine for regulating intestinal flora mainly comprises Mandarin orange collaterals extract,
the medicine comprises the following components in parts by weight: 15-20 parts of tangerine pith extract, 4-6 parts of codonopsis pilosula, 3-4 parts of bighead atractylodes rhizome, 4-5 parts of kudzuvine root, 5-8 parts of astragalus, 2-3 parts of hawthorn, 4-6 parts of cinnamon, 3-4 parts of liquorice, 4-6 parts of hericium erinaceus, 3-4 parts of honey and 15-20 parts of purified water;
the tangerine pith extract is composed of micromolecular pectin and citrus flavone prepared by physically separating the extract of the citrus fiber concentrated solution formed after squeezing and filtering
In the first embodiment, the preparation method of the medicine is as follows:
taking traditional Chinese medicinal materials in parts: steaming 4 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 4 parts of kudzuvine root, 5 parts of astragalus, 4 parts of cinnamon, 3 parts of liquorice and 4 parts of hericium erinaceus for 30 minutes by using steam, naturally cooling, and putting into a pulper for crushing;
step two, putting the crushed Chinese medicinal materials into a heating kettle, sequentially adding purified water, decocting for 20 minutes with strong fire, and then slowly decocting for 60 minutes with slow fire;
step three, after the decoction is finished, the decoction is refrigerated and kept stand for 2 hours in an environment with the temperature of 4 ℃, and the traditional Chinese medicine residues are filtered for later use;
step four, taking 2 parts of hawthorn, peeling, removing kernels, drying in the sun, and grinding into powder for later use;
and step five, sequentially adding the micromolecule pectin and 15 parts of citrus flavone, the hawthorn powder and 3 parts of honey into the filtered liquid medicine, uniformly stirring, and sealing for storage.
Example two, when the medicament is prepared, the preparation method is as follows:
taking traditional Chinese medicinal materials in corresponding parts: 6 parts of codonopsis pilosula, 4 parts of bighead atractylodes rhizome, 5 parts of kudzuvine root, 8 parts of astragalus, 6 parts of cinnamon, 4 parts of liquorice and 6 parts of hericium erinaceus, steaming for 30 minutes by using steam, naturally cooling, and putting into a pulper for crushing;
step two, putting the crushed Chinese medicinal materials into a heating kettle, sequentially adding purified water, decocting for 20 minutes with strong fire, and then slowly decocting for 60-80 minutes with slow fire;
step three, after the decoction is finished, refrigerating and standing for 3 hours at the temperature of 4 ℃, and filtering the traditional Chinese medicine residues for later use;
taking 3 parts of hawthorn, peeling, removing kernels, drying in the sun, and grinding into powder for later use;
and step five, sequentially adding 20 parts of small molecular pectin and citrus flavone, 4 parts of hawthorn powder and 4 parts of honey into the filtered liquid medicine, uniformly stirring, and sealing and storing.
In the third embodiment, the preparation method of the combined preparation is as follows:
taking traditional Chinese medicinal materials in parts: steaming 5 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 5 parts of kudzuvine root, 6 parts of astragalus root, 5 parts of cinnamon, 4 parts of liquorice and 5 parts of hericium erinaceus for 30 minutes by using steam, naturally cooling, and putting into a pulper for crushing;
step two, putting the crushed Chinese medicinal materials into a heating kettle, sequentially adding purified water, decocting for 20 minutes with strong fire, and then slowly decocting for 80 minutes with slow fire;
step three, after the decoction is finished, refrigerating and standing for 3 hours at the temperature of 4 ℃, and filtering the traditional Chinese medicine residues for later use;
step four, taking 3 parts of hawthorn, peeling, removing kernels, drying in the sun, and grinding into powder for later use;
and step five, sequentially adding 18 parts of micromolecular pectin and citrus flavone, 3 parts of hawthorn powder and 3 parts of honey into the filtered liquid medicine, uniformly stirring, and sealing and storing.
Through the integrated use of various traditional Chinese medicinal materials with mild temperament, the tangerine pith extract and beneficial substances contained in the tangerine pith extract, the taste of the medicine for taking can be improved, the medicine for taking is convenient to take regularly and quantitatively, the problem of soreness caused by scapulohumeral periarthritis or shoulder and neck strain can be greatly relieved, and the life quality is improved;
meanwhile, the preparation is convenient, the storage is convenient, and the preparation method is suitable for batch preparation and popularization and use;
the medicine liquid is taken orally, and the medicine dregs are externally applied, so that the treatment effect is better while the utilization rate of the medicinal materials is improved.
The present invention is illustrated by way of example and not by way of limitation. It will be apparent to those skilled in the art that other variations and modifications may be made in the foregoing disclosure without departing from the spirit or essential characteristics of all embodiments, and that all changes and modifications apparent from the above teachings are within the scope of the invention.

Claims (6)

1. The medicine for regulating intestinal flora mainly comprises an extract of citrus reticulata blanco,
the medicine comprises the following components in parts by weight: 15-20 parts of tangerine pith extract, 4-6 parts of codonopsis pilosula, 3-4 parts of bighead atractylodes rhizome, 4-5 parts of kudzuvine root, 5-8 parts of astragalus, 2-3 parts of hawthorn, 4-6 parts of cinnamon, 3-4 parts of liquorice, 4-6 parts of hericium erinaceus, 3-4 parts of honey and 15-20 parts of purified water;
the tangerine pith extract is composed of micromolecular pectin and citrus flavone which are prepared by physically separating an extract of a citrus fiber concentrated solution formed after squeezing and filtering.
2. The medicine mainly takes the citrus reticulata extract as the main ingredient to regulate intestinal flora and is characterized in that,
the medicine comprises the following components in parts by weight: 15 parts of tangerine pith extract, 4 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 4 parts of kudzu root, 6 parts of astragalus membranaceus, 2 parts of hawthorn, 4 parts of cinnamon, 3 parts of liquorice, 4 parts of hericium erinaceus, 3 parts of honey and 15 parts of purified water.
3. The drug for regulating intestinal flora mainly comprising citrus reticulata extract according to claim 1,
the preparation comprises the following medicinal components in parts by weight: 20 parts of tangerine pith extract, 6 parts of codonopsis pilosula, 4 parts of bighead atractylodes rhizome, 5 parts of kudzu root, 8 parts of astragalus membranaceus, 3 parts of hawthorn, 6 parts of cinnamon, 4 parts of liquorice, 6 parts of hericium erinaceus, 4 parts of honey and 20 parts of purified water.
4. The medicine for regulating intestinal flora mainly comprising citrus reticulata extract according to claim 1,
the optimal mixture ratio of the medicine components and the parts is as follows: 18 parts of tangerine pith extract, 5 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 5 parts of kudzu root, 6 parts of astragalus membranaceus, 3 parts of hawthorn, 5 parts of cinnamon, 4 parts of liquorice, 5 parts of hericium erinaceus, 3 parts of honey and 20 parts of purified water.
5. A preparation method of a medicine for regulating intestinal flora mainly by using an orange collaterals extract is characterized in that,
taking traditional Chinese medicinal materials in parts: steaming 4 parts of codonopsis pilosula, 3 parts of bighead atractylodes rhizome, 4 parts of kudzuvine root, 6 parts of astragalus root, 4 parts of cinnamon, 3 parts of liquorice and 4 parts of hericium erinaceus for 30 minutes by using steam, naturally cooling, and putting into a pulper for pulping;
step two, putting the crushed Chinese medicinal materials into a heating kettle, sequentially adding purified water, decocting for 20 minutes with strong fire, and then slowly decocting for 60-80 minutes with slow fire;
step three, after the decoction is finished, the decoction is refrigerated and kept stand for 2 to 3 hours in an environment with the temperature of 4 ℃, and the traditional Chinese medicine residues are filtered for later use;
peeling and removing kernels of the hawthorns, drying in the sun, and grinding into powder for later use;
and step five, sequentially adding the tangerine pith extract, the hawthorn powder and the honey into the filtered liquid medicine, uniformly stirring, and sealing for storage.
6. The method for preparing a drug for regulating intestinal flora mainly comprising citrus reticulata blanco extract according to claim 5,
the dregs obtained by filtering in the third step can be externally applied to navel for use.
CN202310017937.9A 2023-01-06 2023-01-06 Medicine for regulating intestinal flora by using citrus reticulata blanco extract as main component and preparation method Pending CN115919941A (en)

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CN108042631A (en) * 2017-04-01 2018-05-18 杭州络通生物科技有限公司 A kind of new citrus rag extract and preparation method thereof and the medical usage for improving intestinal flora effect
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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CN108042631A (en) * 2017-04-01 2018-05-18 杭州络通生物科技有限公司 A kind of new citrus rag extract and preparation method thereof and the medical usage for improving intestinal flora effect
CN108244620A (en) * 2018-04-18 2018-07-06 中国农业科学院特产研究所 A kind of Hericium erinaceus stomach nourishing granule and preparation method thereof
CN112274565A (en) * 2020-11-24 2021-01-29 南京博医源健康信息咨询有限公司 Formula and preparation method of medicinal and edible herbal tea capable of tonifying qi, invigorating spleen and protecting stomach
CN113143954A (en) * 2021-03-26 2021-07-23 哈尔滨百世普康生物科技有限公司 Novel citrus reticulata extract, preparation method thereof and medical application of novel citrus reticulata extract in improving intestinal flora

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