CN1159059C - Medicine for abstinence of drugs and its prepn. - Google Patents

Abstract

The present invention relates to drug abstinence medicine which is characterized in that the drug abstinence medicine of the present invention is prepared from 30 portions of datura flower, 24 portions of semen momordicae, 24 portions of glaucousback threewingnut root bark, 12 portions of raw monk shood, 12 portions of raw kusnezoff monkshood root, 6 portions of hellebore, 30 portions of raw araceae, 30 of prepared pinellia, 20 portions of ledebouriella root, 20 portions of hemlock parsley and 24 portions of angelica by weight. A production process of the drug abstinence medicine of the present invention has the steps that first, the raw materials are sterilized, cleaned and are sterilized by microwaves; then, the raw materials are cut up; next, the raw monk shood, the raw kusnezoff monkshood root and the hellebore are soaked by 24 hours by clarified well water and are dried in the air; the processed hemlock parsley is soaked for 7 days by urina hominis and is dried in the air; the datura flower, the semen momordicae, the glaucousback threewingnut root bark, the raw araceae, the prepared pinellia, the ledebouriella root, the dahurian angelica and the angelica are dried in the air; the processed raw materials are mixed and are pulverized into 100 meshes of the drug abstinence medicine by a crusher. The drug abstinence medicine is processed into capsules by a conventional process. Products of the present invention have the advantages of outstanding curative effect on drug abstinence, no addiction dependence, high medication safety under the guidance of doctors, short course of treatment high cure rate, no relapse during a treatment period, short drug abstinence time (7 to 10 days) and low relapse rate.

Description

A kind of medicine that is used to quit drug abuse and preparation method thereof

(1) technical field: the present invention relates to a kind of anti-additive medicament that is used to give up Opium, heroin, Clausena lansium (Lour.) Skeels, cocaine, Fructus Cannabis, methamphetamine hydrochloride, head-shaking pill, morphine, dolantin and other analgesia medicine drug addiction, it is to be formed by the pure natural prepared from traditional Chinese medicines.

(2) background technology: overflow of drugs has been world's public hazards, is threatening human survival and development.The eighties in 20th century, the whole world causes 100,000 people's death because of drug abuse, and the nineties, only just there are 500,000 people in the U.S. because of the dead people of drug abuse every year.1999, the number of taking drugs that China Ministry of Public Security registers on the books reached 68.1 ten thousand people, and calendar year 2001 rises to 90.1 ten thousand people, and unregistered number of taking drugs is more surprising.In order to wipe out drugs, countries in the world are strengthened the hitting dynamics to the traffic in drugs personnel on the one hand, on the other hand the drug addict are given up taking addictive drugs by force.However, because unique allure of drugs, traffic in drugs, drug abuse phenomenon remain incessant after repeated prohibition, and become worse.The some people thinks drug rehabilitation really, or the household supervises its drug rehabilitation, because existing drug rehabilitation scheme is not good enough, and causes the patient to hang back.Medicine drug abstinences such as the methadone of being taked at present, naltrexone, buprenorphine, clonidine are not good, and big to the human body toxic and side effects, and the cycle is long, the relapse rate height.As methadone, its effect is an alternative medicine, the mild toxicity big poison of just often saying of generation, and its treatment must notice that as taking drugs the control patient produce new drug dependence early stage, can occur serious symptom after the drug withdrawal and rebound, this is to cause the major reason of reverting to take drugs.China Patent No. is: 90100203.8 patent of invention " drug rehabilitation spirit preparation method ", and its medication preparation complexity, and it is long to give up the course of treatment, is generally 7-30 days.With FUKANG PIAN, An Junning, set upright the drug rehabilitation of Chinese medicine such as health, curative effect is better.As it is peaceful to pacify monarch, is country's " 95 " emphasis tackling of key scientific and technical problems achievement, and this medicine does not have the addiction dependency, fast, safety, treating both the principal and secondary aspects of a disease.But its shortcoming is during suffering from treatment, prevent that the patient from inhaling while guarding against.

(3) summary of the invention: the objective of the invention is a kind of medicine that is used to quit drug abuse of developing at above problem, it is based on Chinese herbal medicine, this medicine is to be made by the raw material of following weight portion, Flos Daturae 30, Semen Momordicae 24, Cortex tripterygii hypoglauci radicis 24, Radix Aconiti 12, Rhizoma et radix veratri (Radix Rhizoma Veratri), Arisaema Cum Bile 30, Rhizoma Pinelliae 30, Radix Saposhnikoviae 20, the Radix Angelicae Dahuricae 20, Rhizoma Chuanxiong 50, Radix Angelicae Sinensis 24.The production technology of anti-additive medicament as previously discussed comprise the following steps: the first step with the sterilization earlier of medicine material Flos Daturae, Semen Momordicae, Cortex tripterygii hypoglauci radicis, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma et radix veratri (Radix Rhizoma Veratri), Arisaema Cum Bile, Rhizoma Pinelliae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, clean and use microwave sterilizating, cut medicine then; The clarifying well water of Radix Aconiti, Rhizoma et radix veratri (Radix Rhizoma Veratri) reuse that second step will handle soaked 24 hours, dried; The Rhizoma Chuanxiong that the 3rd step will handle soaked 7 days with urine of baby boys, dried; The 4th step was dried Flos Daturae, Semen Momordicae, Cortex tripterygii hypoglauci radicis, Arisaema Cum Bile, Rhizoma Pinelliae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis; The 5th step with second and third, raw material in four steps mixes, and is ground into 100 purpose drug-breaking medicine with pulverizer; Raw material during the 6th step went on foot the 5th processes routinely becomes capsule.This product is based on Chinese herbal medicine, has no side effect, and no addiction dependency does not have during treating and reverts to take drugs, and gives up in 7-10 days, and relapse rate is low.Treating 324 routine heroin, Clausena lansium (Lour.) Skeels, dolantin etc. with this product sucks or injects the addict, all drug rehabilitations voluntarily.Male 286 people, women 56 people, the half a year to eight time year of taking drugs, drug abuse every day amount 0.5-4 gram, the people who inhales 1 gram every day accounts for about 80%.Diagnostic criteria has history of drug abuse to continue in drug abuse, and drug abuse every day amount is more than 0.5 gram, and breaking produced the drug rehabilitation symptom in malicious 4-6 hour.As yawn, drop tears, sneeze, rhinorrhea is shaken, from head to foot the acid symptoms such as pain of itching.Urine toxicological analysis assay is positive, or network ketone urges addiction test to be positive, and its Therapeutic Method is: deprive the use of its drugs after the volunteer addict is admitted to hospital, oral above-mentioned anti-additive medicament capsule.The each 1.5-2 gram of heroin abuser was taken medicine once in 8 hours; After spending four, took medicine once in 12 hours; After spending seven, 24 hours clothes once ten days courses of treatment, are sucked the Clausena lansium (Lour.) Skeels person: clothes 2.5-3 gram, took medicine once in 8 hours; After spending four, took medicine once in 12 hours,, took medicine once in 24 hours too in the future, ten days courses of treatment.Its criterion of therapeutical effect is that treatment is: no drug abuse phenomenon in the treatment, through treatment in ten days, drug abuse desire and withdrawal symptom disappeared.Urged addiction to it with Allylnoroxymorphone injection intravenous injection respectively twice in 20-40 minute, no withdrawal symptom occurs, and patient's self-induction is cured, and is considered as fully recovering.In the middle of being in hospital, 342 examples are all cured.Pay a return visit 96 people, male 68 people, women 28 people after six months to 1 year.Male 55 people successfully quit drug abuse, cure rate 80.9%; Women 22 people do not have and revert to take drugs cure rate 78.6%.In sum, the present invention has the drug rehabilitation determined curative effect, no addiction dependency, drug safety under doctor's guidance, short treating period, the good effect that cure rate is high.

The pharmacology of this product is according to being: drugs such as heroin, morphine are the derivants of Opium, and Opium is then astringed the lung, astringing intestine to stop diarrhea, bundle gas contract blood, and the life shape of human body is all supplemented nutrition in QI and blood, suck or shoot up after, it is loose to be so incensed that to shrink vascular, circumfluence do not have to stagnate, make tired person tireless, weary person is no lack of, and spirit suddenly doubles, spirit and QI cleaning, glad incomparable, inhale suction again so thirst for one, form vicious cycle, energy and blood of human body is in by among hard pressed, lacks life.Opium puckery hardship, cold little fire is big, in its poison is gone into, at first invades the lung stomach.Sun is robbed in consumption Tianjin, causes the lung-heat dryness of the stomach, and phlegm retention is overweight, and visible dryness in the nasal cavity is thirsty, eats resembling of constipation less.Because of the diffusing gas of good and foul smells energy, the whole body QI and blood carries the baby and curbs Opium in addition again, and the visible fur of addict is sliding, and muscle does not moisten, muscles and bones is unstrong, a little less than the extremity fistula, and soreness of the waist and knees, cardiopalmus timidness due to deficiency of QI easily, all pathological changes are given birth to and gone out, and are heavy in the past as phlegm retention, and visible dryness in the nasal cavity is thirsty, eats resembling of constipation less.Opium to be again because of the good and foul smells energy gas that looses, and QI and blood all over the body carries the baby and curbs in addition, and the visible fur of addict is sliding, and muscle does not moisten, and muscles and bones is strong, a little less than the extremity flaccidity, and soreness of the waist and knees, cardiopalmus timidness due to deficiency of QI easily, all pathological changes are given birth to and are gone out, and as phlegm retention, gather dysentery, diseases such as asthenia.In case stop inhaling then QI and blood absent-mindedness, lax decadence, be difficult warming the interior and defend table.According to traditional Chinese medical science traditional theory, dialectical opinion is controlled, Flos Daturae, and Semen Momordicae, Cortex tripterygii hypoglauci radicis, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma et radix veratri (Radix Rhizoma Veratri) calming soporific upgrade brain mind; Arisaema Cum Bile, the Rhizoma Pinelliae drink that eliminates the phlegm; The heat clearing away of inducing sweat of Radix Saposhnikoviae, the Radix Angelicae Dahuricae; Rhizoma Chuanxiong is walked string and is invigorated blood circulation; Chinese angelica blood supplementing.Its mixture is eliminating evil to take stopgap measures, and sets upright to effect a permanent cure, and reaches the purpose of drug rehabilitation.

(5) specific embodiment: the present invention is described in further detail below in conjunction with embodiment.

Embodiment 1:

The first step, earlier medicine material Flos Daturae, Semen Momordicae, Cortex tripterygii hypoglauci radicis, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma et radix veratri (Radix Rhizoma Veratri), Arisaema Cum Bile, Rhizoma Pinelliae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Radix Angelicae Sinensis are sterilized, cleaning, microwave sterilizating, the raw material after will sterilize is then cut into slices;

Second goes on foot, Radix Aconiti 12 grams, Radix Aconiti Kusnezoffii 12 grams, Rhizoma et radix veratri (Radix Rhizoma Veratri) 6 grams is soaked with clarifying well water and dried in 7 days;

The 3rd goes on foot, Rhizoma Chuanxiong 50 grams is soaked with urine of baby boys liquid dried in 7 days;

The 4th step, 30 grams of the Rhizoma Pinelliae after will sterilize, Flos Daturae 30 grams, Semen Momordicae 24 grams, Cortex tripterygii hypoglauci radicis 24 grams, Arisaema Cum Bile 30 grams, Radix Saposhnikoviae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Angelicae Sinensis 24 restrain and dry;

The 5th goes on foot, the raw material in two, three steps is mixed, and is ground into 100 purposes, 282 gram drug-breaking medicine with pulverizer;

The 6th the step, with the 5th the step in drug-breaking medicine routinely processes become capsule, every 0.4 the gram;

The 7th step, packing, 100 every bottle.

This product has obtained good effect through clinical verification, below is illustrated with case.

Open * *, the man, 36 years old, over 10 years, once inhaled Clausena lansium (Lour.) Skeels, heroin is eaten more than 30 of good Lean stator one time and also often be can't fall asleep, and eats triazolam.This person Ceng Sanci drug rehabilitation is reverted to take drugs again.Think to quit drug abuse once more, lose the confidence.Before being admitted to hospital, suck heroin 1 gram every day.Say when the patient is admitted to hospital: he will violate addiction about 4 o'clock in the afternoon, and through routine check, the doctor gives 6 according to history of drug abuse and health afternoon 1: 30, patient 4 o'clock and do not have later on and recommit addiction in the afternoon, preceding four days, per 8 hours clothes once, each 6; In the time of 5-7 days, obey once 12 hours every days, each 6.Patient says that this drug effect is truly good, has not wanted to take drugs, and requires to leave hospital working.The doctor agrees, 18 of administrations are obeyed once each 6 after requiring to go home every night.Phone is paid a return visit after six days, determines to give up, and finish the course of treatment.

2, open * *, man, 40 years old.Because of catching drug addiction 5 years accidentally, once gave up to other narcotic house, all to revert to take drugs, every day, the amount of sucking reached more than 2 grams.Calendar year 2001, JIUYUE was admitted to hospital on the 24th, calendar year 2001 JIUYUE left hospital in 30th, nothing is reverted to take drugs.

3, poplar * *, man, 30 years old.Catch drug addiction accidentally because of making friends, inhale every day more than Clausena lansium (Lour.) Skeels 2 gram, produce the addiction shape in 6 hours, shed tears, watery nasal discharge, muscle and arthralgia, have Formica fusca to climb sense.Once drug addiction treatment under others helps, all failure was taken drugs 6 years.On March 9th, 2000 was admitted to hospital, and March 19 gave up.

4, Liu * *, man, 27 years old.Suck Clausena lansium (Lour.) Skeels more than 2 years, more than the every day amount of sucking 1 gram, because of curiosity, contamination before 2 years is difficult to self-control, does not take drugs and just aches all over, myasthenia of limbs.Calendar year 2001, JIUYUE was admitted to hospital on the 18th, calendar year 2001 JIUYUE left hospital in 27th, give up.

5, Lee * *, woman, 27 years old.Catch drug addiction when making friends accidentally, suck every day more than Clausena lansium (Lour.) Skeels 2 gram, do not suck and whole body pain just occurs, weak, spontaneous perspiration, restless can not be slept peacefully endocrine regulation round the clock.Calendar year 2001, JIUYUE was admitted to hospital on the 23rd, and leave hospital October 3 calendar year 2001.Give up.

Claims (2)

1, a kind of medicine that is used to quit drug abuse, it is characterized in that: this medicine is to be made by the raw material of following weight portion, Flos Daturae 30, Semen Momordicae 24, Cortex tripterygii hypoglauci radicis 24, Radix Aconiti 12, Rhizoma et radix veratri (Radix Rhizoma Veratri), Arisaema Cum Bile 30, Rhizoma Pinelliae 30, Radix Saposhnikoviae 20, the Radix Angelicae Dahuricae 20, Rhizoma Chuanxiong 50, Radix Angelicae Sinensis 24.

2, a kind of preparation method of a kind of medicine that is used to quit drug abuse as claimed in claim 1, it is characterized in that, it comprise the following steps: the first step with the sterilization earlier of medicine material Flos Daturae, Semen Momordicae, Cortex tripterygii hypoglauci radicis, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma et radix veratri (Radix Rhizoma Veratri), Arisaema Cum Bile, Rhizoma Pinelliae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, clean and use microwave sterilizating, cut medicine then; The clarifying well water of Radix Aconiti, Rhizoma et radix veratri (Radix Rhizoma Veratri) reuse that second step will handle soaked 24 hours, dried; The Rhizoma Chuanxiong that the 3rd step will handle soaked 7 days with urine of baby boys, dried; The 4th step was dried Flos Daturae, Semen Momordicae, Cortex tripterygii hypoglauci radicis, Arisaema Cum Bile, Rhizoma Pinelliae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis; The 5th step with second and third, raw material in four steps mixes, and is ground into 100 purpose drug-breaking medicine with pulverizer; Raw material during the 6th step went on foot the 5th processes routinely becomes capsule.