CN115884799A - 一种生物能量活性材料及其应用 - Google Patents
一种生物能量活性材料及其应用 Download PDFInfo
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- CN115884799A CN115884799A CN202280004789.0A CN202280004789A CN115884799A CN 115884799 A CN115884799 A CN 115884799A CN 202280004789 A CN202280004789 A CN 202280004789A CN 115884799 A CN115884799 A CN 115884799A
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- Prior art keywords
- hydroxybutyrate
- bioenergy
- active material
- bone
- copolyester
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Abstract
本发明公开了一种生物能量活性材料及其应用，具体公开一种生物能量活性材料，其为生物可降解聚合物；所述生物能量活性材料的降解产物为三羧酸循环和/或糖酵解途径中的代谢中间产物，或者为能够转换生成三羧酸循环和/或糖酵解途径中代谢中间产物的聚合物单体，或者为能够转换生成乙酰辅酶A的聚合物单体。该生物能量活性材料的降解产物经过三羧酸代谢循环或者糖酵解途径为组织细胞提供生物能量，解决传统生物可降解材料无法持续提高细胞中ATP的稳定性和相关生物质活性的问题，在骨组织再生领域尤其是在大段骨缺损修复方面表现出广阔的应用前景。
Description
PCT国内申请，说明书已公开。
Claims (19)
- PCT国内申请，权利要求书已公开。
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| PCT/CN2022/109458 WO2023006113A1 (zh) | 2021-07-30 | 2022-08-01 | 一种生物能量活性材料及其应用 |
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| CN115444985B (zh) * | 2022-09-19 | 2023-09-26 | 中鼎凯瑞科技成都有限公司 | 三磷酸腺苷基高能骨修复材料及其制备方法 |
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| CN112773940A (zh) * | 2021-01-26 | 2021-05-11 | 深圳市创想三维科技有限公司 | 一种3d打印用人工骨支架材料及其制备方法和应用 |
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| CN102936407B (zh) * | 2012-10-19 | 2015-09-30 | 华中科技大学 | 一种基于三羧酸循环的能量生物材料及其制备方法 |
| CN103785059B (zh) * | 2014-01-03 | 2015-12-02 | 朱小龙 | 一种骨修复再生材料及其制备方法 |
| US10113160B2 (en) * | 2014-01-30 | 2018-10-30 | Easel Biotechnologies, Llc | Carbon dioxide fixation via bypassing feedback regulation |
| CN105771000B (zh) * | 2016-02-26 | 2019-07-09 | 华中科技大学 | 一种提供能量的骨修复可降解多孔支架及制备方法、应用 |
| CN107375934B (zh) * | 2017-08-10 | 2020-05-22 | 浙江大学 | 含有果糖-1，6-二磷酸的组合物在制备抗肿瘤药物中的应用 |
| RU2708396C1 (ru) * | 2018-12-19 | 2019-12-06 | Федеральное государственное бюджетное учреждение науки Институт высокомолекулярных соединений Российской академии наук | Биосовместимый биоразлагаемый остеокондуктивный полимерный композиционный материал для регенерации костной ткани |
| CN109676915B (zh) * | 2019-02-15 | 2022-02-15 | 复旦大学 | 一种车轮状多孔支架及其制备方法与应用 |
| CN113546213A (zh) * | 2021-07-30 | 2021-10-26 | 深圳先进技术研究院 | 一种生物能量活性材料及其应用 |
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2021
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| CN112773940A (zh) * | 2021-01-26 | 2021-05-11 | 深圳市创想三维科技有限公司 | 一种3d打印用人工骨支架材料及其制备方法和应用 |
Non-Patent Citations (1)
| Title |
|---|
| 冯静，等: "几种高分子材料的生物降解研究进展", 塑料科技, vol. 39, no. 2, pages 95 - 96 * |
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