CN115884766A - 用于使用中链甘油三酯治疗婴儿痉挛的方法 - Google Patents
用于使用中链甘油三酯治疗婴儿痉挛的方法 Download PDFInfo
- Publication number
- CN115884766A CN115884766A CN202180038956.9A CN202180038956A CN115884766A CN 115884766 A CN115884766 A CN 115884766A CN 202180038956 A CN202180038956 A CN 202180038956A CN 115884766 A CN115884766 A CN 115884766A
- Authority
- CN
- China
- Prior art keywords
- composition
- infantile spasms
- day
- administered
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063032111P | 2020-05-29 | 2020-05-29 | |
| US63/032,111 | 2020-05-29 | ||
| US202163176747P | 2021-04-19 | 2021-04-19 | |
| US63/176,747 | 2021-04-19 | ||
| PCT/US2021/034883 WO2021243226A1 (en) | 2020-05-29 | 2021-05-28 | Methods for the treatment of infantile spasms using medium chain triglycerides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115884766A true CN115884766A (zh) | 2023-03-31 |
Family
ID=78744111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180038956.9A Pending CN115884766A (zh) | 2020-05-29 | 2021-05-28 | 用于使用中链甘油三酯治疗婴儿痉挛的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230181512A1 (https=) |
| EP (1) | EP4157250A4 (https=) |
| JP (1) | JP2023527454A (https=) |
| KR (1) | KR20230018462A (https=) |
| CN (1) | CN115884766A (https=) |
| AU (1) | AU2021281426A1 (https=) |
| CA (1) | CA3184353A1 (https=) |
| WO (1) | WO2021243226A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3595638A4 (en) * | 2017-03-15 | 2020-09-16 | Cerecin Inc. | PHARMACEUTICAL COMPOSITIONS WITH HIGH DRUG LOADS BASED ON MEDIUM-CHAIN TRIGLYCERIDES AND RELATED METHODS |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1649839A (zh) * | 2002-04-30 | 2005-08-03 | 三得利株式会社 | 虾青素中链脂肪酸酯、其制造方法、以及含有其的组合物 |
| CN1972697A (zh) * | 2004-06-17 | 2007-05-30 | 威斯康星校友研究基地 | 治疗发作和发作性疾病的化合物和方法 |
| US20140057885A1 (en) * | 2012-08-21 | 2014-02-27 | Sage Therapeutics, Inc. | Methods of treating epilepsy or status epilepticus |
| US20150342902A1 (en) * | 2014-05-29 | 2015-12-03 | Insys Pharma, Inc. | Stable cannabinoid formulations |
| WO2017204986A1 (en) * | 2016-05-27 | 2017-11-30 | Insys Development Company, Inc. | Stable cannabinoid formulations |
| US20190091178A1 (en) * | 2017-09-26 | 2019-03-28 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
| US20190255003A1 (en) * | 2016-10-24 | 2019-08-22 | University Of South Florida | Delaying latency to seizure by combinations of ketone supplements |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2986268C (en) * | 2015-05-28 | 2024-01-02 | Insys Development Company, Inc. | Stable cannabinoid formulations |
| EP3481387A4 (en) * | 2016-08-11 | 2020-04-08 | Ovid Therapeutics Inc | METHOD AND COMPOSITIONS FOR TREATING EPILEPTIC DISEASES |
| CN110678173B (zh) * | 2017-04-10 | 2023-03-28 | 维塔弗洛国际有限公司 | 用于治疗癫痫的组合物 |
-
2021
- 2021-05-28 JP JP2022573444A patent/JP2023527454A/ja active Pending
- 2021-05-28 EP EP21813824.6A patent/EP4157250A4/en active Pending
- 2021-05-28 WO PCT/US2021/034883 patent/WO2021243226A1/en not_active Ceased
- 2021-05-28 AU AU2021281426A patent/AU2021281426A1/en active Pending
- 2021-05-28 CA CA3184353A patent/CA3184353A1/en active Pending
- 2021-05-28 CN CN202180038956.9A patent/CN115884766A/zh active Pending
- 2021-05-28 US US17/926,472 patent/US20230181512A1/en active Pending
- 2021-05-28 KR KR1020227046044A patent/KR20230018462A/ko active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1649839A (zh) * | 2002-04-30 | 2005-08-03 | 三得利株式会社 | 虾青素中链脂肪酸酯、其制造方法、以及含有其的组合物 |
| CN1972697A (zh) * | 2004-06-17 | 2007-05-30 | 威斯康星校友研究基地 | 治疗发作和发作性疾病的化合物和方法 |
| US20140057885A1 (en) * | 2012-08-21 | 2014-02-27 | Sage Therapeutics, Inc. | Methods of treating epilepsy or status epilepticus |
| CN104736159A (zh) * | 2012-08-21 | 2015-06-24 | 萨奇治疗股份有限公司 | 治疗癫痫或癫痫持续状态的方法 |
| US20150342902A1 (en) * | 2014-05-29 | 2015-12-03 | Insys Pharma, Inc. | Stable cannabinoid formulations |
| WO2017204986A1 (en) * | 2016-05-27 | 2017-11-30 | Insys Development Company, Inc. | Stable cannabinoid formulations |
| US20190255003A1 (en) * | 2016-10-24 | 2019-08-22 | University Of South Florida | Delaying latency to seizure by combinations of ketone supplements |
| US20190091178A1 (en) * | 2017-09-26 | 2019-03-28 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
Non-Patent Citations (1)
| Title |
|---|
| ADAM L. NUMIS等: "The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms", EPILEPSY RESEARCH, 22 June 2011 (2011-06-22), pages 172 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20230181512A1 (en) | 2023-06-15 |
| CA3184353A1 (en) | 2021-12-02 |
| AU2021281426A1 (en) | 2023-02-02 |
| WO2021243226A1 (en) | 2021-12-02 |
| EP4157250A1 (en) | 2023-04-05 |
| JP2023527454A (ja) | 2023-06-28 |
| EP4157250A4 (en) | 2024-06-19 |
| KR20230018462A (ko) | 2023-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |