CN115804824A - Traditional Chinese medicine prescription for eliminating phlegm and relieving cough - Google Patents
Traditional Chinese medicine prescription for eliminating phlegm and relieving cough Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine prescription for eliminating phlegm and relieving cough, belonging to the field of traditional Chinese medicine preparations. The invention comprises the following raw materials by weight: 20-45 parts of bulbus fritillariae cirrhosae, 35-45 parts of semen raphani, 20-30 parts of fructus momordicae, 25-30 parts of radix stemonae, 70-75 parts of cortex mori radicis, 50-72 parts of pinellia ternate, 60-66 parts of radix asteris, 1-4 parts of fructus forsythiae, 20-25 parts of pumice, 3-6 parts of liquorice, 5-10 parts of wintersweet and 20-35 parts of semen cassiae.
Description
Technical Field
The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine formula for eliminating phlegm and relieving cough.
Background
Cough and excessive phlegm are common symptoms of respiratory diseases, and the cough is caused by inflammation, foreign matters, physical or chemical stimulation of trachea, bronchial mucosa or pleura, is protective respiratory reflex action of a human body for removing secretions or foreign matters in respiratory tracts, and is two most common symptoms of patients with respiratory diseases. Severe long-term coughing can lead to respiratory tract bleeding. Has many main treatment functions of chemical drugs and traditional Chinese medicines, and has the effects of relieving cough, eliminating phlegm and resisting inflammation.
At present, the treatment medicines for eliminating phlegm and relieving cough can be divided into two categories of western medicines and traditional Chinese medicines, wherein the western medicines are divided into central cough-relieving medicines, peripheral cough-relieving medicines or both of the central cough-relieving medicines and the peripheral cough-relieving medicines according to different action mechanisms. The central antitussive medicine is used to suppress cough center and selectively suppress cough reflex. The peripheral antitussives are mainly used for relieving cough through local anesthesia of bronchus, and have the function of relieving cough slightly. The traditional Chinese medicine has the advantages of mild medicine property and small side effect in the treatment process, and is widely applied.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine prescription for reducing phlegm and relieving cough, which aims to solve the problems in the background technology.
The purpose of the invention can be realized by the following technical scheme:
a traditional Chinese medicine prescription for eliminating phlegm and relieving cough comprises the following raw materials in parts by weight: 20-45 parts of bulbus fritillariae cirrhosae, 35-45 parts of semen raphani, 20-30 parts of fructus momordicae, 25-30 parts of radix stemonae preparata, 70-75 parts of cortex mori, 50-72 parts of pinellia ternate, 60-66 parts of radix asteris, 1-4 parts of fructus forsythiae, 20-25 parts of pumice, 3-6 parts of liquorice, 5-10 parts of wintersweet and 20-35 parts of semen cassiae.
Further, the prescription comprises the following raw materials in percentage by weight: 30-40 parts of bulbus fritillariae cirrhosae, 37-42 parts of semen raphani, 22-24 parts of fructus momordicae, 25-28 parts of radix stemonae, 72-74 parts of cortex mori, 65-70 parts of pinellia ternate, 62-64 parts of radix asteris, 2-3 parts of fructus forsythiae, 20-22 parts of pumice, 3-5 parts of liquorice, 5-7 parts of wintersweet and 25-30 parts of semen cassiae.
Further, the preparation method of the prescription comprises the following steps:
(1) Removing impurities from Raphani semen, radix Stemonae, rhizoma Pinelliae and radix Asteris, cleaning, parching with slow fire to dark yellow, and taking out;
(2) Oven drying Bulbus Fritillariae Cirrhosae, fructus Siraitiae Grosvenorii, and Pumex at low temperature, pulverizing, and sieving;
(3) Adding the Chinese medicinal materials processed in the steps (1) and (2) into a container, adding cortex mori radicis, fructus forsythiae, liquorice, wintersweet and semen cassiae, adding 5-10 times of water, decocting for 2 times, filtering, combining the filtrates, standing, filtering again, concentrating the filtrate, and drying to obtain the formula.
Further, the drying temperature in the step (2) is controlled to be 80-100 ℃, and the time is 20-30 minutes.
Further, sieving by a sieve with 80-120 meshes in the step (2).
Further, in the step (3), the decoction is carried out for the first time until the volume of the solution is 0.2 to 0.5 times of the volume of the original solution, water is supplemented to the initial position, and the decoction is concentrated for the second time until the volume of the solution is 0.2 to 0.3 times of the volume of the original solution.
Further, the specific steps of the first decoction are boiling with strong fire and then decocting with slow fire.
Further, the second decocting step comprises boiling with strong fire, decocting for 25-35min, and decocting with slow fire to 0.2-0.3 times of the original volume.
Advantageous effects
The traditional Chinese medicine formula for reducing phlegm and relieving cough is prepared by taking bulbus fritilariae, semen raphani, momordica grosvenori, radix stemonae, cortex mori radicis, pinellia ternate, aster, fructus forsythiae, pumice, liquorice, wintersweet and semen cassiae as raw materials through a preparation method of frying and decocting. The traditional Chinese medicine components are reasonably configured according to the principle of monarch, minister, assistant and guide, so that the traditional Chinese medicine composition has no toxic or side effect on human bodies, has the effects of diminishing inflammation and eliminating phlegm, is clinically used for treating symptoms such as cough caused by exogenous wind-heat, unsmooth expectoration and the like, and has a remarkable curative effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A traditional Chinese medicine prescription for eliminating phlegm and relieving cough comprises the following raw materials in parts by weight: 20 parts of bulbus fritillariae cirrhosae, 35 parts of semen raphani, 20 parts of fructus momordicae, 25 parts of radix stemonae, 70 parts of cortex mori, 50 parts of pinellia ternate, 60 parts of radix asteris, 1 part of fructus forsythiae, 20 parts of pumice, 3 parts of liquorice, 5 parts of wintersweet and 20 parts of semen cassiae.
The preparation method of the prescription comprises the following steps:
(1) Removing impurities from Raphani semen, radix Stemonae, rhizoma Pinelliae and radix Asteris, cleaning, parching with slow fire to dark yellow, and taking out;
(2) Taking bulbus fritilariae, fructus momordicae and pumice, drying at 80 ℃ for 20 minutes, crushing and sieving with a 80-mesh sieve;
(3) Adding the Chinese medicinal materials treated in the steps (1) and (2) into a container, adding cortex mori radicis, fructus forsythiae, liquorice, wintersweet and semen cassiae, adding 10 times of water, decocting for 2 times, boiling with strong fire for the first time, decocting with small fire until the volume of the original solution is 0.2 times that of the original solution, supplementing water to an initial position, boiling with strong fire for the second time, continuing decocting for 25min, turning to the small fire until the volume of the original solution is 0.2 times that of the original solution, filtering, combining the filtrates, standing, filtering, concentrating the filtrate, and drying to obtain the formula.
Example 2
A traditional Chinese medicine prescription for eliminating phlegm and relieving cough comprises the following raw materials in parts by weight: 45 parts of bulbus fritillariae cirrhosae, 45 parts of semen raphani, 30 parts of fructus momordicae, 30 parts of radix stemonae, 75 parts of cortex mori, 72 parts of pinellia ternate, 66 parts of radix asteris, 4 parts of fructus forsythiae, 25 parts of pumice, 6 parts of liquorice, 10 parts of wintersweet and 35 parts of semen cassiae.
The preparation method of the prescription comprises the following steps:
(1) Removing impurities from Raphani semen, radix Stemonae, rhizoma Pinelliae and radix Asteris, cleaning, parching with slow fire to dark yellow, and taking out;
(2) Taking bulbus fritilariae, fructus momordicae and pumice, controlling the drying temperature at 100 ℃, drying for 30 minutes, crushing and sieving with a 120-mesh sieve;
(3) Adding the Chinese medicinal materials treated in the step (1) and the step (2) into a container, adding cortex mori radicis, fructus forsythiae, liquorice, wintersweet and semen cassiae, adding 10 times of water, decocting for 2 times, decocting with strong fire for the first time until the mixture is boiled with small fire until the volume of the solution is 0.5 times of the volume of the original solution, supplementing water to the initial position, decocting with strong fire for the second time until the mixture is boiled with large fire for the second time until the mixture is boiled with small fire until the volume of the solution is 0.3 times of the volume of the original solution, filtering, combining the filtrates, standing, filtering, concentrating and drying the filtrate to obtain the formula.
Example 3
A traditional Chinese medicine prescription for eliminating phlegm and relieving cough comprises the following raw materials in parts by weight: 30 parts of bulbus fritillariae cirrhosae, 37 parts of semen raphani, 22 parts of momordica grosvenori, 25 parts of radix stemonae, 72 parts of cortex mori radicis, 65 parts of pinellia ternate, 62 parts of aster, 2 parts of fructus forsythiae, 20 parts of pumice, 3 parts of liquorice, 5 parts of wintersweet and 25 parts of semen cassiae.
The preparation method of the prescription comprises the following steps:
(1) Removing impurities from Raphani semen, radix Stemonae, rhizoma Pinelliae and radix Asteris, cleaning, parching with slow fire to dark yellow, and taking out;
(2) Taking bulbus fritilariae, fructus momordicae and pumice, drying at 80 ℃ for 20 minutes, crushing and sieving with a 80-mesh sieve;
(3) Adding the Chinese medicinal materials treated in the step (1) and the step (2) into a container, adding cortex mori radicis, fructus forsythiae, liquorice, wintersweet and semen cassiae, adding 10 times of water, decocting for 2 times, decocting with strong fire for the first time until the mixture is boiled with small fire until the volume of the solution is 0.2 times of the volume of the original solution, supplementing water to the initial position, decocting with strong fire for the second time until the mixture is boiled with large fire for the second time until the mixture is boiled with small fire until the volume of the solution is 0.2 times of the volume of the original solution, filtering, combining the filtrates, standing, filtering, concentrating and drying the filtrate to obtain the formula.
Example 4
A traditional Chinese medicine prescription for eliminating phlegm and relieving cough comprises the following raw materials in parts by weight: 40 parts of bulbus fritillariae cirrhosae, 42 parts of semen raphani, 24 parts of momordica grosvenori, 28 parts of radix stemonae, 74 parts of cortex mori radicis, 70 parts of pinellia ternate, 64 parts of aster, 3 parts of fructus forsythiae, 22 parts of pumice, 5 parts of liquorice, 7 parts of wintersweet and 30 parts of semen cassiae.
The preparation method of the prescription comprises the following steps:
(1) Removing impurities from Raphani semen, radix Stemonae, rhizoma Pinelliae and radix Asteris, cleaning, parching with slow fire to deep yellow, and taking out;
(2) Taking bulbus fritilariae, fructus momordicae and pumice, controlling the drying temperature at 100 ℃, drying for 30 minutes, crushing and sieving with a 80-mesh sieve;
(3) Adding the Chinese medicinal materials treated in the step (1) and the step (2) into a container, adding cortex mori radicis, fructus forsythiae, liquorice, wintersweet and semen cassiae, adding 10 times of water, decocting for 2 times, decocting with strong fire for the first time until the mixture is boiled with small fire until the volume of the solution is 0.2 times of the volume of the original solution, supplementing water to the initial position, decocting with strong fire for the second time until the mixture is boiled with large fire for the second time until the mixture is boiled with small fire until the volume of the solution is 0.2 times of the volume of the original solution, filtering, combining the filtrates, standing, filtering, concentrating and drying the filtrate to obtain the formula.
Testing and detecting:
the application of the phlegm-eliminating prescription (examples 1-4) obtained by the invention is as follows:
1. test materials:
taking 150 mice, each half of the mice are male and female, the weight of the mice is 18-22 g, and the mice are randomly divided into 10 groups: blank control group (1 group), positive control group (1 group), traditional Chinese medicine low dose group (4 groups) and traditional Chinese medicine high dose group (4 groups), each group contains 15. All mice were placed in mouse metabolism cages and fed in SPF-level environment. After 3 days of acclimation, each group of mice was gavaged 1 time per day for 7 consecutive days. Groups of mice were intragastrically administered according to the dosing schedule of table 1 below. Ammonium chloride was produced by gonghong honghe pharmaceutical company, llc, under the national drug standard H51021409.
Table 1:
after the last administration for 0.5h, each mouse was intraperitoneally injected with 0.1ml (5 mg)/10 g of phenol red solution, and after 30min, the animals were sacrificed, the tissues around the trachea were dissected off, a section of trachea from the thyroid cartilage to the tracheal branch was cut off, placed in a 2ml physiological saline tube, and then 0.1ml sodium hydroxide solution was added, and the OD value was measured at 546nm using a 721 type spectrophotometer. A standard curve was prepared using phenol red, and the phenol red content (. Mu.g/ml) was calculated from the curve. The results are shown in Table 2.
Table 2:
as can be seen from tables 1-2, the phlegm eliminating prescription provided by the invention can remarkably promote the excretion of phenol red, and the effect of eliminating phlegm is close to that of ammonium chloride, thus indicating that the phlegm eliminating prescription provided by the invention has remarkable effect of eliminating phlegm.
In the description of the specification, reference to the description of "one embodiment," "an example," "a specific example" or the like means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing is illustrative and explanatory only, and it will be appreciated by those skilled in the art that various modifications, additions and substitutions can be made to the embodiments described without departing from the scope of the invention as defined in the appended claims.
Claims (8)
1. A traditional Chinese medicine prescription for eliminating phlegm and relieving cough is characterized in that: the prescription comprises the following raw materials in percentage by weight: 20-45 parts of bulbus fritillariae cirrhosae, 35-45 parts of semen raphani, 20-30 parts of fructus momordicae, 25-30 parts of radix stemonae, 70-75 parts of cortex mori radicis, 50-72 parts of pinellia ternate, 60-66 parts of radix asteris, 1-4 parts of fructus forsythiae, 20-25 parts of pumice, 3-6 parts of liquorice, 5-10 parts of wintersweet and 20-35 parts of semen cassiae.
2. The traditional Chinese medicine prescription for resolving phlegm and relieving cough according to claim 1, characterized in that: the prescription comprises the following raw materials in percentage by weight: 30-40 parts of bulbus fritillariae cirrhosae, 37-42 parts of semen raphani, 22-24 parts of momordica grosvenori, 25-28 parts of radix stemonae, 72-74 parts of cortex mori, 65-70 parts of pinellia ternate, 62-64 parts of aster, 2-3 parts of fructus forsythiae, 20-22 parts of pumice, 3-5 parts of liquorice, 5-7 parts of wintersweet and 25-30 parts of semen cassiae.
3. The traditional Chinese medicine prescription for resolving phlegm and relieving cough according to claim 1, characterized in that: the preparation method of the prescription comprises the following steps:
(1) Removing impurities from Raphani semen, radix Stemonae, rhizoma Pinelliae and radix Asteris, cleaning, parching with slow fire to deep yellow, and taking out;
(2) Oven drying Bulbus Fritillariae Cirrhosae, fructus Siraitiae Grosvenorii, and Pumex at low temperature, pulverizing, and sieving;
(3) Adding the Chinese medicinal materials treated in the steps (1) and (2) into a container, adding cortex mori radicis, fructus forsythiae, liquorice, wintersweet and semen cassiae, adding 5-10 times of water, decocting for 2 times, filtering, combining filtrates, standing, filtering again, concentrating the filtrate and drying to obtain the formula.
4. The traditional Chinese medicine prescription for resolving phlegm and relieving cough according to claim 3, characterized in that: in the step (2), the drying temperature is controlled to be 80-100 ℃ and the time is 20-30 minutes.
5. The traditional Chinese medicine prescription for resolving phlegm and relieving cough according to claim 3, characterized in that: and (3) sieving by using a sieve of 80-120 meshes in the step (2).
6. The traditional Chinese medicine prescription for resolving phlegm and relieving cough according to claim 3, characterized in that: in the step (3), the decoction is carried out for the first time until the volume of the solution is 0.2 to 0.5 times of the volume of the original solution, water is supplemented to the initial position, and the decoction is concentrated for the second time until the volume of the solution is 0.2 to 0.3 times of the volume of the original solution.
7. The traditional Chinese medicine formula for resolving phlegm and stopping coughing according to claim 6, wherein: the first decoction specifically comprises the steps of boiling with strong fire and then decocting with small fire.
8. The traditional Chinese medicine prescription for resolving phlegm and relieving cough as claimed in claim 6, wherein the second decoction comprises boiling with strong fire, decocting for 25-35min, and decocting with slow fire to 0.2-0.3 times of the original solution volume.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116077601A (en) * | 2023-04-07 | 2023-05-09 | 江西草珊瑚药业有限公司 | Lozenge for clearing heat, relieving cough and reducing sputum and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109589381A (en) * | 2017-09-30 | 2019-04-09 | 徐宏亮 | A kind of Chinese medicinal formulae of preventing phlegm from forming and stopping coughing |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109589381A (en) * | 2017-09-30 | 2019-04-09 | 徐宏亮 | A kind of Chinese medicinal formulae of preventing phlegm from forming and stopping coughing |
Non-Patent Citations (1)
| Title |
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| 寅生;: "润肺止咳饮治疗顽固性久咳56例", 内蒙古中医药, no. 32, pages 19 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116077601A (en) * | 2023-04-07 | 2023-05-09 | 江西草珊瑚药业有限公司 | Lozenge for clearing heat, relieving cough and reducing sputum and preparation method thereof |
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