CN104940763A - Traditional Chinese medicine preparation for treating primary pulmonary tuberculosis - Google Patents
Traditional Chinese medicine preparation for treating primary pulmonary tuberculosis Download PDFInfo
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- CN104940763A CN104940763A CN201510376746.7A CN201510376746A CN104940763A CN 104940763 A CN104940763 A CN 104940763A CN 201510376746 A CN201510376746 A CN 201510376746A CN 104940763 A CN104940763 A CN 104940763A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating primary pulmonary tuberculosis. The preparation comprises the following traditional Chinese medicine components in parts by weight: 10-25 parts of platycodon root, 10-20 parts of heartleaf houttuynia herb, 10-30 parts of sessile stemona root, 10-30 parts of cochinchnese asparagus root, 5-15 parts of ripe Chinese date seed, 10-30 parts of unibract fritillary bulb, 10-30 parts of dwarf lilyturf tuber, 10-20 parts of Chinese wolfberry root-bark, 10-30 parts of common anemarrhena rhizome, 10-30 parts of common bletilla pseudobulb, 10-25 parts of lotus rhizome node and 5-15 parts of liquorice root. The traditional Chinese medicine preparation can achieve the effect of obviously improving the symptoms of patients, such as cough, profuse phlegm due to breathlessness, phlegm stench and hoarseness, and achieve the functions of tonifying the lung and promoting tissue regeneration, strengthening the spleen and benefiting qi, moistening the lung by nourishing yin and resolving phlegm and relieving cough. The traditional Chinese medicine preparation is precise in composition, uses fewer medicines, has specific effects and has good curative effects on pulmonary tuberculosis.
Description
Technical field
The invention belongs to medicine field, relate to a kind of Chinese medicine preparation for the treatment of primary pulmonary tuberculosis.
Background technology
Typical case's pulmonary tuberculosis onset is slow, and the course of disease is longer, has low grade fever, asthenia, inappetence, cough and spits blood on a small quantity.But most of patients focus is slight, without remarkable symptom, be occasionally found when x-ray physical examination.Also having so spits blood with sky is just made a definite diagnosis, and reviewing its medical history can have slight General Symptoms.Small number of patients because of unexpected onset and outstanding signs of toxicity and respiratory symptom, and confirms as acute military tuberculosis or caseous pneumonia through x-ray inspection.The primary pulmonary tuberculosis course of disease is all generally optimum.Morbidity starts after 3 ~ June to absorb or scleroma, can absorb recovery from illness and calcification in 2 years.But under human body internal and external environment unfavorable conditions, pathological changes can be in progress or even worsen.More common person has following several: 1. scorching around primary tumor or the large subordinate of perilymphadenitis is optimum, can absorb within 3 ~ June; 2. there is pleural effusion; 3. tuberculosis spreads in bronchus and causes endobronchial tuberculosis to mostly occur just to contaminate in latter 6 months at infant.Lack effective medicine at present.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of primary pulmonary tuberculosis and preparation method thereof, it is simple, evident in efficacy that this Chinese medicine preparation has preparation, effectively can treat pulmonary tuberculosis.
The technical solution adopted in the present invention is as follows:
A kind of Chinese medicine preparation for the treatment of primary pulmonary tuberculosis, raw material is made up of the Chinese medicinal components of following weight portion: Radix Platycodonis 10 ~ 25 parts, Herba Houttuyniae 10 ~ 20 parts, the Radix Stemonae 10 ~ 30 parts, Radix Asparagi 10 ~ 30 parts, ripe Semen Ziziphi Spinosae 5 ~ 15 parts, Bulbus Fritillariae Cirrhosae 10 ~ 25 parts, Radix Ophiopogonis 10 ~ 30 parts, Cortex Lycii 10 ~ 20 parts, the Rhizoma Anemarrhenae 10 ~ 30 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 30 parts, Nodus Nelumbinis Rhizomatis 10 ~ 25 parts, Radix Glycyrrhizae Preparata 5 ~ 15 parts;
Its preparation method is:
(1) get Radix Platycodonis, Herba Houttuyniae, the Radix Stemonae, Radix Asparagi, ripe Semen Ziziphi Spinosae, Bulbus Fritillariae Cirrhosae, Radix Ophiopogonis, Cortex Lycii, the Rhizoma Anemarrhenae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Nodus Nelumbinis Rhizomatis, Radix Glycyrrhizae Preparata respectively, clean, dry;
(2) take by weight: Radix Platycodonis 10 ~ 25 parts, Herba Houttuyniae 10 ~ 20 parts, the Radix Stemonae 10 ~ 30 parts, Radix Asparagi 10 ~ 30 parts, ripe Semen Ziziphi Spinosae 5 ~ 15 parts, Bulbus Fritillariae Cirrhosae 10 ~ 25 parts, Radix Ophiopogonis 10 ~ 30 parts, Cortex Lycii 10 ~ 20 parts, the Rhizoma Anemarrhenae 10 ~ 30 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 30 parts, Nodus Nelumbinis Rhizomatis 10 ~ 25 parts, Radix Glycyrrhizae Preparata 5 ~ 15 parts;
(3) by after the mixing of load weighted Chinese medicine, the ratio being 1:10 in the ratio of medicine and water decocts;
(4) (3) gained is boiled liquid to filter, obtain solution, obtain extractum by concentrated for gained solution, then gained extractum is dissolved in the concentration of extractum weight 4 ~ 12 times of weight is in the ethanol water according to weighing scale 96%, be uniformly mixed, quantitative separating, obtain oral liquid formulations.
The above a kind of Chinese medicine preparation for the treatment of primary pulmonary tuberculosis, raw material is preferably made up of the Chinese medicinal components of following weight portion: Radix Platycodonis 15 ~ 20 parts, Herba Houttuyniae 15 ~ 20 parts, the Radix Stemonae 15 ~ 25 parts, Radix Asparagi 15 ~ 25 parts, ripe Semen Ziziphi Spinosae 5 ~ 10 parts, Bulbus Fritillariae Cirrhosae 10 ~ 15 parts, Radix Ophiopogonis 15 ~ 25 parts, Cortex Lycii 10 ~ 15 parts, the Rhizoma Anemarrhenae 10 ~ 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 15 parts, Nodus Nelumbinis Rhizomatis 10 ~ 20 parts, Radix Glycyrrhizae Preparata 5 ~ 10 parts; The best is preferably made up of the Chinese medicinal components of following weight portion: Radix Platycodonis 15 parts, Herba Houttuyniae 20 parts, the Radix Stemonae 25 parts, Radix Asparagi 25 parts, ripe Semen Ziziphi Spinosae 10 parts, Bulbus Fritillariae Cirrhosae 10 parts, Radix Ophiopogonis 15 parts, Cortex Lycii 10 parts, the Rhizoma Anemarrhenae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Nodus Nelumbinis Rhizomatis 10 parts, Radix Glycyrrhizae Preparata 10 parts.
The above preparation method technique is simple, and can remain the effective ingredient in medical material completely, and the efficacy of a drug is lasting, and be convenient to take, mouthfeel is good.
The pharmaceutical characteristic of each raw material is as follows:
Radix Platycodonis: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Herba Houttuyniae: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Control pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.
The Radix Stemonae: root is used as medicine, outward for parasite killing, antipruritic, delousing; For oral administration have lung moistening, cough-relieving, the effect of eliminating the phlegm.
Radix Asparagi: YIN nourishing and the production of body fluid promoting, diphtheria.Relieve internal heat anticancer, clear gesture reduced phlegm, nourshing Yin and drynsessmoistening prescription, record in " not Lu ": Baoding lung qi, cold removing heat, supports skin, physical strength profiting, diuresis, cold and can mend.
Bulbus Fritillariae Cirrhosae: for the deficiency of the lung, chronic cough, cough due to consumptive disease, cough caused by dryness-heat, dry cough few expectorant, sputum with blood, lung abscess, scrofula, carbuncle, acute mastitis.
Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Cortex Lycii: removing heat from blood removes and steams, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.Interior-heat is quenched one's thirst.
The Rhizoma Anemarrhenae: nourishing YIN to lower pathogenic fire, moisturizes laxation.Control dysphoria with smothery sensation to quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.
The Pseudobulbus Bletillae (Rhizoma Bletillae): astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Nodus Nelumbinis Rhizomatis: Compendium of Material Medica: repercussive blood, relieving heat toxin." book on Chinese herbal medicine is looked for the truth ": Nodus Nelumbinis Rhizomatis puckery.With Radix Rehmanniae juice urine of baby boys.It is kind that only all tell epistaxis disease." Bencao Congxin ": relieving heat toxin, repercussive blood, treatment blood in puerperal is vexed.
Radix Glycyrrhizae Preparata: Radix Glycyrrhizae has antiinflammatory, anti-allergic effects, can protect throat and the tunica mucosa tracheae of inflammation.Radix Glycyrrhizae extractum and glycyrrhizic acid have the Detoxication of similar glucuronic acid to some poisonous substance.
The present invention is on the basis of Chinese medicine traditional theory, in conjunction with medication experience among the people, uses modern scientific theory formulated.In formula, Herba Houttuyniae, Bulbus Fritillariae Cirrhosae, Radix Ophiopogonis, Cortex Lycii, the Rhizoma Anemarrhenae are mainly used in heat-clearing and toxic substances removing, cool the blood dissipate blood stasis, subduing swelling and relieving pain, astringing to arrest bleeding, benefiting qi and raising yang; Add and join the Radix Stemonae, Radix Platycodonis, Bulbus Fritillariae Cirrhosae be mainly used in removing heat-phlegm, sending down the abnormal ascending QI cough-relieving; Join again Radix Asparagi, Radix Ophiopogonis, for removing heat from blood pathogenic fire purging, nourshing Yin and drynsessmoistening prescriptionly to promote the production of body fluid, astringing lung QI for relieving asthma, nourishing YIN and moistening the lung; Finally add with Radix Glycyrrhizae Preparata, reach antiinflammatory, antiallergic, throat and the tunica mucosa tracheae of inflammation can be protected, alleviate pain relieving.All medicines share to be played altogether, obviously can improve patient's cough, excessive phlegm out of breath, expectorant is stench, the symptom such as hoarseness, reaches tonifying the lung tissue regeneration promoting, invigorating the spleen and benefiting QI, nourishing YIN and moistening the lung, the effects such as preventing phlegm from forming and stopping coughing.Prescription of the present invention is rigorous, parum drug and centralize the power, has good curative effect to pulmonary tuberculosis.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, but do not limit the scope of the invention and range of application:
One, a kind of Chinese medicine preparation for the treatment of primary pulmonary tuberculosis makes the preparation method of oral liquid
1. EXPERIMENTAL DESIGN:
This test 5 embodiments are prepared into oral liquid respectively, and design parameter refers to table 1.
Table 1 embodiment preparation parameter table
| Embodiment | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
| Radix Platycodonis (part) | 15 | 15 | 20 | 10 | 25 |
| Herba Houttuyniae (part) | 20 | 15 | 20 | 20 | 10 |
| The Radix Stemonae (part) | 25 | 15 | 25 | 10 | 30 |
| Radix Asparagi (part) | 25 | 25 | 15 | 10 | 30 |
| Ripe Semen Ziziphi Spinosae (part) | 10 | 5 | 10 | 5 | 15 |
| Radix Ophiopogonis (part) | 15 | 15 | 25 | 30 | 10 |
| Bulbus Fritillariae Cirrhosae | 10 | 15 | 20 | 10 | 15 |
| Cortex Lycii (part) | 10 | 10 | 15 | 20 | 10 |
| The Rhizoma Anemarrhenae (part) | 15 | 10 | 15 | 10 | 30 |
| The Pseudobulbus Bletillae (Rhizoma Bletillae) (part) | 15 | 10 | 15 | 30 | 10 |
| Nodus Nelumbinis Rhizomatis (part) | 10 | 20 | 10 | 10 | 25 |
| Radix Glycyrrhizae Preparata (part) | 10 | 5 | 10 | 15 | 5 |
| Ethanol water (doubly) | 6 | 5 | 4 | 7 | 8 |
2. operating procedure:
(1) get Radix Platycodonis, Herba Houttuyniae respectively, the Radix Stemonae, Radix Asparagi, ripe Semen Ziziphi Spinosae, Bulbus Fritillariae Cirrhosae, Radix Ophiopogonis, Cortex Lycii, the Rhizoma Anemarrhenae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Nodus Nelumbinis Rhizomatis, Radix Glycyrrhizae Preparata, clean, dry;
(2) take by table 1 weight portion: Radix Platycodonis, Herba Houttuyniae, the Radix Stemonae, Radix Asparagi, ripe Semen Ziziphi Spinosae, Bulbus Fritillariae Cirrhosae, Radix Ophiopogonis, Cortex Lycii, the Rhizoma Anemarrhenae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Nodus Nelumbinis Rhizomatis, Radix Glycyrrhizae Preparata;
3) by after the mixing of load weighted Chinese medicine, the ratio being 1:10 in the ratio of medicine and water decocts;
(4) (3) gained is boiled liquid to filter, obtain solution, obtain extractum by concentrated for gained solution, then gained extractum is dissolved in the ethanol water of 96%, is uniformly mixed, and quantitative separating obtains oral liquid formulations.
Two, clinical trial:
(1) clinical data
The present inventor in 2004 so far, carries out clinical observation treatment to 80 routine lungers, wherein man 32 example, and female 48 example, the age is between 5 ~ 40 years old.
(2) Therapeutic Method
Oral, three times on the one, each 5 ~ 20ml, one after each meal.Calculate treatment time according to conditions of patients weight, patients with mild takes about 4 months, and severe case serve on 10 months and can fully recover.
(3) curative effect determinate standard:
Cure: symptom all disappears; Main Physico-chemical tests index is normally.
Effective: symptomatology is eliminated or cardinal symptom is eliminated; Physico-chemical tests index is normal.
Effective: cardinal symptom disappears substantially; Main Physico-chemical tests index makes moderate progress.
Invalid: main Physico-chemical tests index is front unchanged with treatment.
(4) clinical effectiveness
Clinical cure 62 example (77.5%), effective 10 examples (12.5%), effective 4 examples (5%), invalid 2 examples (2.5%), total effective rate is 97.5%.
Be below several model case:
Case 1 Huang, female, 38 years old.Cough and expectoration, chest pain, half a year out of breath are many, send a telegraph certain examination in hospital, are diagnosed as primary pulmonary tuberculosis.Take the embodiment of the present invention 1 sample, a 15ml, 4 times on the one, serve on 7, cough is gradually few, breathes and takes a turn for the better, and continues medication 1 month, and above symptom is eliminated, and hospital carries out Physico-chemical tests, and result is normal, recovery from illness.
Case 2, Chen, man, 5 years old, low grade fever, cough, excessive phlegm out of breath over 1 month, expectorant was smelt as of rotten fish, and lack of appetite, becomes thin gradually, to certain examination in hospital, is diagnosed as pulmonary tuberculosis.Take the embodiment of the present invention 1 sample, a 5ml, 3 times on the one, serve on cough purulent sputum on the 7th and reduce, to breathe and suitable, diet increases, and muscle power is gradually multiple.After continuing to take 4 months, recovery from illness.
Claims (3)
1. treat a Chinese medicine preparation for primary pulmonary tuberculosis, it is characterized in that: raw material is made up of the Chinese medicinal components of following weight portion:
Radix Platycodonis 10 ~ 25 parts, Herba Houttuyniae 10 ~ 20 parts, the Radix Stemonae 10 ~ 30 parts, Radix Asparagi 10 ~ 30 parts, ripe Semen Ziziphi Spinosae 5 ~ 15 parts, Radix Ophiopogonis 10 ~ 30 parts, Bulbus Fritillariae Cirrhosae 10 ~ 20 parts, Cortex Lycii 10 ~ 20 parts, the Rhizoma Anemarrhenae 10 ~ 30 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 30 parts, Nodus Nelumbinis Rhizomatis 10 ~ 25 parts, Radix Glycyrrhizae Preparata 5 ~ 15 parts;
Its preparation method is:
(1) get Radix Platycodonis, Herba Houttuyniae, the Radix Stemonae, Radix Asparagi, ripe Semen Ziziphi Spinosae, Bulbus Fritillariae Cirrhosae, Radix Ophiopogonis, Cortex Lycii, the Rhizoma Anemarrhenae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Nodus Nelumbinis Rhizomatis, Radix Glycyrrhizae Preparata respectively, clean, dry;
(2) take by weight: Radix Platycodonis 10 ~ 25 parts, Herba Houttuyniae 10 ~ 20 parts, the Radix Stemonae 10 ~ 30 parts, Radix Asparagi 10 ~ 30 parts, ripe Semen Ziziphi Spinosae 5 ~ 15 parts, Bulbus Fritillariae Cirrhosae 10 ~ 25 parts, Radix Ophiopogonis 10 ~ 30 parts, Cortex Lycii 10 ~ 20 parts, the Rhizoma Anemarrhenae 10 ~ 30 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 30 parts, Nodus Nelumbinis Rhizomatis 10 ~ 25 parts, Radix Glycyrrhizae Preparata 5 ~ 15 parts;
(3) by after the mixing of load weighted Chinese medicine, the ratio being 1:10 in the ratio of medicine and water decocts;
(4) (3) gained is boiled liquid to filter, obtain solution, obtain extractum by concentrated for gained solution, then gained extractum is dissolved in the concentration of extractum weight 4 ~ 12 times of weight is in the ethanol water according to weighing scale 96%, be uniformly mixed, quantitative separating, obtain oral liquid formulations.
2. a kind of Chinese medicine preparation for the treatment of primary pulmonary tuberculosis according to claim 1, it is characterized in that: raw material is made up of the Chinese medicinal components of following weight portion: Radix Platycodonis 15 ~ 20 parts, Herba Houttuyniae 15 ~ 20 parts, the Radix Stemonae 15 ~ 25 parts, Radix Asparagi 15 ~ 25 parts, ripe Semen Ziziphi Spinosae 5 ~ 10 parts, Radix Ophiopogonis 15 ~ 25 parts, Bulbus Fritillariae Cirrhosae 10 ~ 15 parts, Cortex Lycii 10 ~ 15 parts, the Rhizoma Anemarrhenae 10 ~ 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 15 parts, Nodus Nelumbinis Rhizomatis 10 ~ 20 parts, Radix Glycyrrhizae Preparata 5 ~ 10 parts.
3. a kind of Chinese medicine preparation for the treatment of primary pulmonary tuberculosis according to claim 1 or 2, it is characterized in that: raw material is made up of the Chinese medicinal components of following weight portion: Radix Platycodonis 15 parts, Herba Houttuyniae 20 parts, the Radix Stemonae 25 parts, Radix Asparagi 25 parts, ripe Semen Ziziphi Spinosae 10 parts, Bulbus Fritillariae Cirrhosae 10 parts, Radix Ophiopogonis 15 parts, Cortex Lycii 10 parts, the Rhizoma Anemarrhenae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Nodus Nelumbinis Rhizomatis 10 parts, Radix Glycyrrhizae Preparata 10 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110841016A (en) * | 2019-12-10 | 2020-02-28 | 姚建远 | Traditional Chinese medicine formula for treating pediatric pulmonary portal lymphoid tuberculosis and preparation method thereof |
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