CN115777783A - Health beverage for preventing gastroesophageal reflux and preparation method thereof - Google Patents
Health beverage for preventing gastroesophageal reflux and preparation method thereof Download PDFInfo
- Publication number
- CN115777783A CN115777783A CN202210777685.5A CN202210777685A CN115777783A CN 115777783 A CN115777783 A CN 115777783A CN 202210777685 A CN202210777685 A CN 202210777685A CN 115777783 A CN115777783 A CN 115777783A
- Authority
- CN
- China
- Prior art keywords
- gastroesophageal reflux
- health
- percent
- water
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000021302 gastroesophageal reflux disease Diseases 0.000 title claims abstract description 28
- 235000013361 beverage Nutrition 0.000 title claims abstract description 21
- 230000036541 health Effects 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 30
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 22
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims abstract description 19
- 235000009467 Carica papaya Nutrition 0.000 claims abstract description 19
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract description 19
- 235000010413 sodium alginate Nutrition 0.000 claims abstract description 19
- 239000000661 sodium alginate Substances 0.000 claims abstract description 19
- 229940005550 sodium alginate Drugs 0.000 claims abstract description 19
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 15
- 241001116389 Aloe Species 0.000 claims abstract description 14
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 14
- 235000021552 granulated sugar Nutrition 0.000 claims abstract description 14
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 13
- 239000004376 Sucralose Substances 0.000 claims abstract description 13
- 235000010418 carrageenan Nutrition 0.000 claims abstract description 13
- 239000000679 carrageenan Substances 0.000 claims abstract description 13
- 229940113118 carrageenan Drugs 0.000 claims abstract description 13
- 229920001525 carrageenan Polymers 0.000 claims abstract description 13
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 13
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 13
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 13
- 235000019408 sucralose Nutrition 0.000 claims abstract description 13
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims abstract description 13
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims abstract description 13
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000006264 Asimina triloba Nutrition 0.000 claims abstract description 9
- 235000020185 raw untreated milk Nutrition 0.000 claims abstract description 9
- 235000017557 sodium bicarbonate Nutrition 0.000 claims abstract description 9
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract description 9
- 235000020197 coconut milk Nutrition 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 235000013305 food Nutrition 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims description 15
- 238000003756 stirring Methods 0.000 claims description 15
- 238000001816 cooling Methods 0.000 claims description 12
- 230000001954 sterilising effect Effects 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 11
- 238000000265 homogenisation Methods 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 10
- 240000006432 Carica papaya Species 0.000 claims description 9
- 235000010216 calcium carbonate Nutrition 0.000 claims description 8
- 238000009924 canning Methods 0.000 claims description 7
- 239000005457 ice water Substances 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 7
- 239000003292 glue Substances 0.000 claims description 6
- 238000002844 melting Methods 0.000 claims description 6
- 230000008018 melting Effects 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 240000004181 Eucalyptus cladocalyx Species 0.000 claims description 5
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 5
- 239000000084 colloidal system Substances 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 230000007935 neutral effect Effects 0.000 claims description 3
- 208000024891 symptom Diseases 0.000 abstract description 10
- 239000002253 acid Substances 0.000 abstract description 9
- 206010067171 Regurgitation Diseases 0.000 abstract description 7
- 201000006549 dyspepsia Diseases 0.000 abstract description 6
- 208000024798 heartburn Diseases 0.000 abstract description 5
- 230000035622 drinking Effects 0.000 abstract description 4
- 239000000796 flavoring agent Substances 0.000 abstract description 4
- 235000019634 flavors Nutrition 0.000 abstract description 4
- 235000016709 nutrition Nutrition 0.000 abstract description 3
- 230000002265 prevention Effects 0.000 abstract description 2
- 244000189799 Asimina triloba Species 0.000 abstract 1
- 230000035764 nutrition Effects 0.000 abstract 1
- 241000219173 Carica Species 0.000 description 9
- 230000000694 effects Effects 0.000 description 7
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 210000003238 esophagus Anatomy 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 238000010992 reflux Methods 0.000 description 5
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 4
- 239000004365 Protease Substances 0.000 description 4
- 229910001424 calcium ion Inorganic materials 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 235000013162 Cocos nucifera Nutrition 0.000 description 3
- 244000060011 Cocos nucifera Species 0.000 description 3
- 235000010410 calcium alginate Nutrition 0.000 description 3
- 239000000648 calcium alginate Substances 0.000 description 3
- 229960002681 calcium alginate Drugs 0.000 description 3
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 108010004032 Bromelains Proteins 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 206010030216 Oesophagitis Diseases 0.000 description 2
- 108090000526 Papain Proteins 0.000 description 2
- 235000019835 bromelain Nutrition 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 208000006881 esophagitis Diseases 0.000 description 2
- 210000003236 esophagogastric junction Anatomy 0.000 description 2
- 235000015203 fruit juice Nutrition 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 210000001156 gastric mucosa Anatomy 0.000 description 2
- 210000003736 gastrointestinal content Anatomy 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 229940055729 papain Drugs 0.000 description 2
- 235000019834 papain Nutrition 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 1
- 244000099147 Ananas comosus Species 0.000 description 1
- 235000007119 Ananas comosus Nutrition 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010015137 Eructation Diseases 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 206010061968 Gastric neoplasm Diseases 0.000 description 1
- 208000005577 Gastroenteritis Diseases 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 208000037147 Hypercalcaemia Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 241000199919 Phaeophyceae Species 0.000 description 1
- 108010064851 Plant Proteins Proteins 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 238000009098 adjuvant therapy Methods 0.000 description 1
- 229940006091 aloe polysaccharide Drugs 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 208000027687 belching Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003613 bile acid Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 239000001362 calcium malate Substances 0.000 description 1
- OLOZVPHKXALCRI-UHFFFAOYSA-L calcium malate Chemical compound [Ca+2].[O-]C(=O)C(O)CC([O-])=O OLOZVPHKXALCRI-UHFFFAOYSA-L 0.000 description 1
- 229940016114 calcium malate Drugs 0.000 description 1
- 235000011038 calcium malates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 238000005341 cation exchange Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 235000020510 functional beverage Nutrition 0.000 description 1
- 238000002523 gelfiltration Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000008821 health effect Effects 0.000 description 1
- 235000020627 health maintaining nutrition Nutrition 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 230000000148 hypercalcaemia Effects 0.000 description 1
- 208000030915 hypercalcemia disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000025402 neoplasm of esophagus Diseases 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 235000021118 plant-derived protein Nutrition 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000036186 satiety Effects 0.000 description 1
- 235000019627 satiety Nutrition 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Images
Abstract
The invention discloses a healthy beverage for preventing gastroesophageal reflux and a preparation method thereof. The raw materials comprise the following components in percentage by weight: 2.00-4.00% of white granulated sugar, 2.00-4.00% of sodium alginate, 1.00-2.00% of calcium carbonate, 1.00-2.00% of baking soda, 0.05-0.07% of sucralose, 35.00-50.00% of raw milk or 10.00-20.00% of coconut milk, 3.00-5.00% of aloe concentrated juice, 3.00-5.00% of pawpaw concentrated juice, 0.02-0.04% of carrageenan, 0.15-0.25% of microcrystalline cellulose, 0.05-0.20% of food essence, 0.07-0.10% of monoglyceride and the balance of water. The health beverage has the advantages of pleasant flavor, health and nutrition, convenient drinking, prevention of heartburn, acid regurgitation and other uncomfortable symptoms caused by gastroesophageal reflux and the like.
Description
Technical Field
The invention relates to a healthy beverage for preventing gastroesophageal reflux and a preparation method thereof, belonging to the technical field of functional beverages.
Background
Gastroesophageal reflux disease (GERD) refers to a disease in which the contents of the gastroduodenal tract reflux into the esophagus to cause heartburn, chest pain, acid regurgitation and other symptoms, and can cause esophagitis, damage to tissues outside the esophagus and other complications. The risk factors for the onset of GERD include age, sex, smoking, increased Body Mass Index (BMI), excessive alcohol consumption, drug use, etc. Overweight is an important risk factor for GERD, and weight loss can reduce reflux symptoms in GERD patients.
Sodium alginate is an edible macromolecular polysaccharide which is not digested by human bodies and is extracted from brown algae, and is widely applied to dairy products and beverages. The sodium alginate has the effects of water absorption, adsorption, cation exchange, gel filtration and the like in the stomach and intestine, and has unique regulation effect on the metabolism of a human body. The sodium alginate is combined with calcium ions to form calcium alginate gel which can protect gastric mucosa and form a gastroesophageal 'valve' to prevent the reflux of the stomach esophagus; besides, the sodium alginate also has the functions of reducing blood pressure, reducing blood fat, reducing cholesterol in a body and preventing fatty liver; increase satiety and lose weight healthily; accelerate gastrointestinal peristalsis and prevent constipation.
Aloe contains polysaccharides, anthraquinones, amino acids, enzymes, polypeptides, vitamins and minerals, and has health promoting effects. The aloe polysaccharide has better repairing effect on gastric mucosa injury caused by alcohol. Calcium malate in aloe has very good effect on suppressing acid regurgitation.
Papaya contains papain, an enzyme that helps break down proteins and carbohydrates. Bromelain is a proteolytic enzyme contained in pineapples and, like papain, it also promotes digestion of proteins. Bromelain also has anti-inflammatory activity, can help digestion, and has adjuvant treatment effect on gastroenteritis and dyspepsia.
At present, no report is available about the preparation of a healthy beverage with the efficacy of preventing gastroesophageal reflux by using the ingredients, and no such product exists in the market.
Disclosure of Invention
The purpose of the invention is: provides a healthy beverage for preventing gastroesophageal reflux and a preparation method thereof. White granulated sugar, sodium alginate, calcium carbonate, baking soda, sucralose, raw milk, coconut milk, matcha powder, fruit juice, carrageenan, microcrystalline cellulose, monoglyceride and essence for food are processed into the healthy beverage which has pleasant flavor, is healthy and nutritional and convenient to drink and can prevent the reflux of stomach and esophagus by a scientific and reasonable processing technology.
In order to achieve the purpose, the invention provides a health beverage for preventing gastroesophageal reflux, which comprises the following raw materials in percentage by weight: 2.00-4.00% of white granulated sugar, 2.00-4.00% of sodium alginate, 1.00-2.00% of calcium carbonate, 1.00-2.00% of baking soda, 0.05-0.07% of sucralose, 35.00-50.00% of raw milk, 10.00-20.00% of coconut milk, 3.00-5.00% of aloe concentrated juice, 3.00-5.00% of pawpaw concentrated juice, 0.02-0.04% of carrageenan, 0.15-0.25% of microcrystalline cellulose, 0.05-0.20% of food essence, 0.07-0.10% of monoglyceride and the balance of water.
Preferably, the health drink is a neutral drink having a pH of 6.0 to 8.5.
The invention also provides a preparation method of the health beverage for preventing gastroesophageal reflux, which comprises the following steps:
step 1: weighing the raw materials according to the composition proportion for later use;
step 2: glue melting: uniformly mixing weighed white granulated sugar, sodium alginate, carrageenan, microcrystalline cellulose and monoglyceride, adding the mixture into hot water while stirring, and stirring until colloid is fully mixed with water for later use, wherein the mass ratio of the mixture to the water is 1g;
and 3, step 3: and (3) secondary blending: adding weighed calcium carbonate, sodium bicarbonate, sucralose, raw milk, coconut pulp, matcha powder and papaya juice into the sugar gum solution obtained in the step 2, stirring until the materials are fully dissolved, adding water to a constant volume to obtain a required weight, and adding food essence;
and 4, step 4: homogenizing: heating the feed liquid prepared in the step 3, and carrying out secondary homogenization treatment;
and 5: canning: canning the homogenized feed liquid;
step 6: and (3) sterilization: sterilizing the canned feed liquid;
and 7: and (3) cooling: and (5) cooling the sterilized sample in an ice water bath to finish the preparation of the sample.
Preferably, the temperature of the hot water in the step 1 is 55-65 ℃; the heating temperature in the step 4 is 60-70 ℃, the pressure of the secondary homogenization is 30-50bar and 150-250bar respectively, and the temperature is 60-70 ℃.
Preferably, the sterilization conditions in step 6 are as follows: sterilizing in water bath at 85-95 deg.C for 20-40min; and (3) cooling the sterilized sample in the step (7) to 15-20 ℃ through an ice water bath.
The main action mechanism of the health beverage for preventing the backflow of the gastroesophageal is that after a neutral product is drunk, calcium carbonate in the stomach is dissolved in an acid environment to release calcium ions, sodium alginate and the calcium ions in the acid environment are combined to form calcium alginate gel which is not digested and absorbed by human bodies, baking soda locked in the gel releases carbon dioxide gas in the acid environment to enable the calcium alginate gel to float to the upper part of the stomach contents, and thus a layer of gel 'valve' is formed at the gastroesophageal part to prevent the stomach contents from flowing backwards to enter an esophagus tube, as shown in figure 1.
Compared with the prior art, the invention has the beneficial effects that:
(1) The health-care beverage with the effect of preventing gastroesophageal reflux is developed by utilizing the principle that sodium alginate, calcium carbonate and sodium bicarbonate form suspended gel under the gastric acidity condition and combining aloe juice, papaya juice, milk and the like, and is pleasant in flavor, healthy and nutritional, and convenient to drink;
(2) The invention is prepared by key processes of dissolving white granulated sugar, sodium alginate, calcium carbonate, baking soda, sucralose, raw milk, coconut milk, matcha powder, fruit juice, carrageenan, microcrystalline cellulose, monoglyceride and food essence by glue melting, blending, constant volume, homogenizing, filling, sterilizing and the like;
(3) The product prepared by the invention has the advantages of pleasant flavor, healthy nutrition, convenient drinking, prevention of heartburn, acid regurgitation and other uncomfortable symptoms caused by the reflux of the stomach and esophagus, and the like.
(4) The product of the invention is rich in dietary fiber, and the content of the white granulated sugar is reduced, thereby meeting the low-sugar high-fiber health life requirements of people at present.
Drawings
FIG. 1 is a schematic view illustrating the principle of the health drink for preventing backflow of the gastroesophageal junction according to the present invention;
fig. 2 is a flow chart of the preparation process of the health drink for preventing the backflow of the gastroesophageal junction.
Detailed Description
In order to make the invention more comprehensible, preferred embodiments are described in detail below with reference to the accompanying drawings.
Example 1
The formula of the milk-containing beverage-the health beverage for preventing the gastroesophageal reflux comprises the following components:
3.00 percent of white granulated sugar, 3.00 percent of sodium alginate, 1.50 percent of calcium carbonate, 1.00 percent of baking soda, 0.05 percent of sucralose, 40.00 percent of raw milk, 3.00 percent of aloe concentrated juice, 3.00 percent of pawpaw concentrated juice, 0.02 percent of carrageenan, 0.20 percent of microcrystalline cellulose, 0.06 percent of pawpaw essence, 0.07 percent of monoglyceride and the balance of water.
The manufacturing process is shown in fig. 2, and comprises the following steps:
the first step is as follows: weighing the raw materials according to the composition proportion for later use;
the second step is that: glue melting: uniformly mixing weighed white granulated sugar, sodium alginate, carrageenan, microcrystalline cellulose and monoglyceride, stirring while adding the mixture into hot water at the temperature of 60 ℃, wherein the ratio of the materials to the water is 1g:30g, stirring for 20min until the colloid is fully hydrated for later use.
The third step: and (3) secondary blending: adding weighed calcium carbonate, sodium bicarbonate, sucralose, raw milk, aloe juice and papaya juice into the sugar gum solution prepared in the second step, stirring for 15min until the materials are fully dissolved, setting the volume to 1kg, and adding papaya essence.
The fourth step: homogenizing: and (3) carrying out water bath on the feed liquid prepared in the third step to 70 ℃, and carrying out secondary homogenization treatment under the homogenization condition of 40bar/200bar at the temperature of 65 ℃.
The fifth step: canning: the homogenized material liquid was dispensed into 50mL glass bottles and capped.
And a sixth step: and (3) sterilization: the canned feed liquid is sterilized in water bath at 85 deg.C/30 min.
The seventh step: and (3) cooling: and cooling the sterilized sample to 20 ℃ through ice water bath, and finishing the sample preparation.
Example 2
The formula of the plant protein beverage-the health beverage for preventing the gastroesophageal reflux comprises the following components:
3.00 percent of white granulated sugar, 3.00 percent of sodium alginate, 1.50 percent of calcium carbonate, 1.00 percent of baking soda, 0.05 percent of sucralose, 10.00 percent of coconut milk, 3.00 percent of aloe concentrated juice, 3.00 percent of pawpaw concentrated juice, 0.03 percent of carrageenan, 0.25 percent of microcrystalline cellulose, 0.08 percent of coconut essence, 0.06 percent of pawpaw essence, 0.10 percent of monoglyceride and the balance of water.
The manufacturing process is shown in fig. 2, and comprises the following steps:
the first step is as follows: weighing the raw materials according to the composition proportion for later use;
the second step is that: glue melting: uniformly mixing weighed white granulated sugar, sodium alginate, carrageenan, microcrystalline cellulose and monoglyceride, stirring while adding the mixture into hot water at the temperature of 60 ℃, wherein the ratio of the materials to the water is 1g:30g, stirring for 20min until the colloid is fully hydrated for later use.
The third step: and (3) secondary blending: adding weighed calcium carbonate, sodium bicarbonate, sucralose, coconut milk, aloe juice and papaya juice into the sugar gum solution prepared in the second step, stirring for 15min until the materials are fully dissolved, fixing the volume to 1kg, and adding coconut essence and papaya essence.
The fourth step: homogenizing: and (3) carrying out water bath on the feed liquid prepared in the third step to 70 ℃, and carrying out secondary homogenization treatment under the homogenization condition of 40bar/200bar at the temperature of 65 ℃.
The fifth step: canning: the homogenized material liquid was dispensed into 50mL glass bottles and capped.
And a sixth step: and (3) sterilization: the canned feed liquid is sterilized in water bath at 85 deg.C/30 min.
The seventh step: and (3) cooling: and cooling the sterilized sample to 20 ℃ through ice water bath, and finishing the sample preparation.
Example 3
The formula of the plant beverage-health beverage for preventing gastroesophageal reflux comprises the following components:
3.00 percent of white granulated sugar, 3.00 percent of sodium alginate, 1.50 percent of calcium carbonate, 1.00 percent of baking soda, 0.05 percent of sucralose, 3.00 percent of aloe concentrated juice, 3.00 percent of pawpaw concentrated juice, 0.02 percent of carrageenan, 0.20 percent of microcrystalline cellulose, 0.04 percent of aloe essence, 0.06 percent of pawpaw essence and the balance of water.
The manufacturing process is shown in fig. 2, and comprises the following steps:
the first step is as follows: weighing the raw materials according to the composition proportion for later use;
the second step is that: glue melting: uniformly mixing weighed white granulated sugar, sodium alginate, carrageenan and microcrystalline cellulose, stirring and adding the mixture into hot water at the temperature of 60 ℃ according to a material-water ratio of 1g:30g, stirring for 20min until the colloid is fully hydrated for later use.
The third step: and (3) secondary blending: adding weighed calcium carbonate, sodium bicarbonate, sucralose, aloe juice and papaya juice into the sugar gum solution prepared in the second step, stirring for 15min until the materials are fully dissolved, fixing the volume to 1kg, and adding aloe essence and papaya essence.
The fourth step: homogenizing: and (3) carrying out water bath on the feed liquid prepared in the third step to 70 ℃, and carrying out secondary homogenization treatment under the homogenization condition of 40bar/200bar at the temperature of 65 ℃.
The fifth step: canning: the homogenized material liquid was dispensed into 50mL glass bottles and capped.
And a sixth step: and (3) sterilization: the canned feed liquid is sterilized in water bath at 85 deg.C/30 min.
The seventh step: and (3) cooling: and cooling the sterilized sample to 20 ℃ through ice water bath, and finishing the sample preparation.
Efficacy verification of healthy beverage for preventing gastroesophageal reflux
1. Research method
1.1 volunteer collection
The inventor collected 50 volunteers self-reported to have gastroesophageal reflux disease in the Ministry of Shanghai between 12 months and 2022 months in 2021, with the age of 25-45 years, unlimited nature and course of disease of 1-3 years.
1.2 volunteer's diagnosis and record
Patients have typical clinical symptoms including regurgitation, acid regurgitation, belching, heartburn, etc.;
western medicine diagnosis and disease classification of gastroesophageal reflux disease are mainly based on the expert consensus of gastroesophageal reflux disease in China 2020;
the traditional Chinese medicine diagnosis is based on the cold-heat mixed disease in the opinion on the combined diagnosis and treatment of gastroesophageal reflux disease;
relevant examination proves esophageal pH monitoring, esophageal bile acid monitoring and the like;
informed consent of the patient was obtained in the present study protocol
1.3 exclusion criteria
Patients with combined severe heart, liver, kidney disease;
patients with combined stomach and esophageal tumors and drug-induced esophagitis symptoms;
the product has high content of sodium ions and calcium ions, and people who need to limit the intake of calcium and sodium in diet;
hypercalcemia patients, renal calcification and recurring calcium-containing renal stones;
patients with severe allergic reactions to the study treatment;
2. test method
2.1 grouping of participants
The screened participants were randomly divided into two groups: the treatment group had 20 cases and the blank group had 20 cases. The data of age and disease condition of two groups are not significantly different and are comparable.
2.2 Drinking mode
2.2.1 the treatment group drunk the product beverage, one bottle (50 mL) in the morning, at noon and at night, and the specific drinking time is after meal. The treatment course is 7 days.
2.2.2 blank group drink placebo beverage one bottle (50 mL) each in the morning, evening and after a specific time meal. The treatment course is 7 days.
2.3 therapeutic criteria
And (3) healing: the clinical symptoms completely disappeared.
Improvement: the clinical symptoms are relieved, and the disease condition is controlled.
And (4) invalidation: the clinical symptoms are not obviously improved or aggravated.
2.4 therapeutic results
Wherein: total effective rate = cure rate + improvement rate
3. Conclusion of the experiment
The health beverage prepared by the invention can safely and effectively improve the discomfort symptoms such as acid regurgitation, heartburn and the like caused by gastroesophageal reflux, and has no toxic or side effect.
The above-described embodiments are only preferred embodiments of the present invention, and are not intended to limit the present invention in any way and substantially, it should be noted that those skilled in the art may make several modifications and additions without departing from the scope of the present invention, which should also be construed as a protection scope of the present invention.
Claims (5)
1. A health beverage for preventing gastroesophageal reflux is characterized in that the raw materials comprise the following components in percentage by weight: 2.00-4.00% of white granulated sugar, 2.00-4.00% of sodium alginate, 1.00-2.00% of calcium carbonate, 1.00-2.00% of baking soda, 0.05-0.07% of sucralose, 35.00-50.00% of raw milk or 10.00-20.00% of coconut milk, 3.00-5.00% of aloe concentrated juice, 3.00-5.00% of pawpaw concentrated juice, 0.02-0.04% of carrageenan, 0.15-0.25% of microcrystalline cellulose, 0.05-0.20% of food essence, 0.07-0.10% of monoglyceride and the balance of water.
2. The health drink according to claim 1, wherein the health drink is a neutral drink having a pH of 6.0 to 8.5.
3. The method for preparing a health drink for preventing gastroesophageal reflux according to claim 1 or 2, wherein the method comprises the steps of:
step 1: weighing the raw materials according to the composition proportion for later use;
step 2: glue melting: uniformly mixing weighed white granulated sugar, sodium alginate, carrageenan, microcrystalline cellulose and monoglyceride, adding the mixture into hot water according to a material-water ratio of 1g to 1g while stirring, and stirring until colloid is fully hydrated for later use;
and step 3: and (3) secondary blending: adding weighed calcium carbonate, sodium bicarbonate, sucralose, raw milk, coconut milk, matcha powder and papaya juice into the sugar gum solution obtained in the step 2, stirring until the materials are fully dissolved, adding water to a constant volume to a required weight, and adding food essence;
and 4, step 4: homogenizing: heating the feed liquid prepared in the step (3), and carrying out secondary homogenization treatment;
and 5: canning: canning the homogenized feed liquid;
step 6: and (3) sterilization: sterilizing the canned feed liquid;
and 7: and (3) cooling: and cooling the sterilized sample in an ice water bath to finish the preparation of the sample.
4. The method for preparing a health drink for preventing gastroesophageal reflux according to claim 3, wherein the temperature of the hot water in the step 1 is 55-65 ℃; the heating temperature in the step 4 is 60-70 ℃, the pressure of the secondary homogenization is 30-50bar and 150-250bar respectively, and the temperature is 60-70 ℃.
5. The method for preparing a health drink for preventing gastroesophageal reflux according to claim 3, wherein the sterilization conditions in the step 6 are: sterilizing in water bath at 85-95 deg.C for 20-40min; and (4) cooling the sterilized sample in the step (7) to 15-20 ℃ through an ice water bath.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210777685.5A CN115777783A (en) | 2022-07-04 | 2022-07-04 | Health beverage for preventing gastroesophageal reflux and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210777685.5A CN115777783A (en) | 2022-07-04 | 2022-07-04 | Health beverage for preventing gastroesophageal reflux and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115777783A true CN115777783A (en) | 2023-03-14 |
Family
ID=85431301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210777685.5A Pending CN115777783A (en) | 2022-07-04 | 2022-07-04 | Health beverage for preventing gastroesophageal reflux and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115777783A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4140760A (en) * | 1976-11-09 | 1979-02-20 | Reckitt & Colman Products Limited | Pharmaceutical compositions for use in the suppression of gastric reflux |
| US5213794A (en) * | 1990-11-17 | 1993-05-25 | Bayer Aktiengesellschaft | Antacid preparation having a prolonged gastric residence time |
| CN103249317A (en) * | 2010-08-13 | 2013-08-14 | 热尔韦法国达能公司 | Product for the upper gastric sphere |
| CN105764355A (en) * | 2013-11-25 | 2016-07-13 | 雀巢产品技术援助有限公司 | Milk based nutritional composition and gastric comfort |
| CN109432233A (en) * | 2018-12-07 | 2019-03-08 | 纽湃腾（北京）医药科技有限公司 | A kind of suppression reflux shield stomach composition and application containing Hericium erinaceus extract |
| CN109432232A (en) * | 2018-12-07 | 2019-03-08 | 纽湃腾（北京）医药科技有限公司 | It is a kind of to improve the alginate compositions for adjusting gastroesophageal reflux and application |
| CN111227156A (en) * | 2020-01-20 | 2020-06-05 | 陕西科技大学 | Solid beverage for inhibiting acid regurgitation and preparation method thereof |
| CN111264727A (en) * | 2019-04-04 | 2020-06-12 | 成都图径生物科技有限公司 | Cubilose-flavored suspended protein beverage and preparation method thereof |
| CN111388436A (en) * | 2020-04-20 | 2020-07-10 | 北京健讯医药科技有限公司 | Sodium alginate chewable tablet and preparation method thereof |
-
2022
- 2022-07-04 CN CN202210777685.5A patent/CN115777783A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4140760A (en) * | 1976-11-09 | 1979-02-20 | Reckitt & Colman Products Limited | Pharmaceutical compositions for use in the suppression of gastric reflux |
| US5213794A (en) * | 1990-11-17 | 1993-05-25 | Bayer Aktiengesellschaft | Antacid preparation having a prolonged gastric residence time |
| CN103249317A (en) * | 2010-08-13 | 2013-08-14 | 热尔韦法国达能公司 | Product for the upper gastric sphere |
| CN105764355A (en) * | 2013-11-25 | 2016-07-13 | 雀巢产品技术援助有限公司 | Milk based nutritional composition and gastric comfort |
| CN109432233A (en) * | 2018-12-07 | 2019-03-08 | 纽湃腾（北京）医药科技有限公司 | A kind of suppression reflux shield stomach composition and application containing Hericium erinaceus extract |
| CN109432232A (en) * | 2018-12-07 | 2019-03-08 | 纽湃腾（北京）医药科技有限公司 | It is a kind of to improve the alginate compositions for adjusting gastroesophageal reflux and application |
| CN111264727A (en) * | 2019-04-04 | 2020-06-12 | 成都图径生物科技有限公司 | Cubilose-flavored suspended protein beverage and preparation method thereof |
| CN111227156A (en) * | 2020-01-20 | 2020-06-05 | 陕西科技大学 | Solid beverage for inhibiting acid regurgitation and preparation method thereof |
| CN111388436A (en) * | 2020-04-20 | 2020-07-10 | 北京健讯医药科技有限公司 | Sodium alginate chewable tablet and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101700063B (en) | Preparation method of herbal yogurt with digestion promoting function | |
| CN108812909B (en) | Complementary food nutritional supplement for improving monophagia or anorexia and preparation method thereof | |
| CN110338402A (en) | A kind of compound probiotic powder and preparation method thereof | |
| CN101077208A (en) | Fruits concentrating multi-flavor beverage | |
| CN101720956A (en) | Banana drink and method for preparing same | |
| CN104509901A (en) | Nymphaea tetragona plant probiotic multi-flavor health beverage | |
| CN108740620A (en) | A kind of prune clear beverage and preparation method thereof | |
| CN102232598A (en) | Folium mori fermented drink | |
| CN114376237A (en) | Sea cucumber peptide composite powder and preparation method thereof | |
| CN112167639A (en) | Composition for bidirectionally regulating morning-onset intestinal fluid balance, preparation method and application thereof | |
| CN111820348A (en) | Saussurea involucrata culture ossein peptide composite fruit juice and preparation method thereof | |
| CN111647488A (en) | Medicinal and edible kidney tonifying wine and preparation method thereof | |
| CN115777783A (en) | Health beverage for preventing gastroesophageal reflux and preparation method thereof | |
| CN110559389A (en) | traditional Chinese medicine wine for treating hyperuricemia, gout and rheumatism and preparation method thereof | |
| CN106070636A (en) | A kind of free from lactose antihyperglycemic milk and production method thereof | |
| CN108143975A (en) | A kind of Chinese medicine composition, composite preparation and preparation method for treating children's having indigestion | |
| CN106800992A (en) | Mulberry fruit donkey-hide gelatin ginseng liquor and preparation method thereof | |
| CN109758568B (en) | A composition containing black-bone chicken egg white peptide, and its application in preparing medicines, antifatigue health food and food for treating dysmenorrhea | |
| CN1251278A (en) | Vinegar-honey cola drink and its preparation method | |
| CN113197268A (en) | Sobering and liver-protecting soft drink and preparation method thereof | |
| CN105876557A (en) | Radix Puerariae liver protecting beverage and preparation method thereof | |
| CN110679808A (en) | Colored jam and cubilose beverage and preparation method thereof | |
| CN110710623A (en) | Natural stevia rebaudiana functional health-care beverage | |
| EP1796696B1 (en) | Compounds, compositions, formulations and process for preparation thereof and method of treatment and management of acidity and related disorders | |
| KR20060064040A (en) | Emotional tea collagen vita citrus junos tea |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |