CN115711864A - Exhaled gas gastrointestinal tract disease determination system and method - Google Patents

Exhaled gas gastrointestinal tract disease determination system and method Download PDF

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CN115711864A
CN115711864A CN202211457514.0A CN202211457514A CN115711864A CN 115711864 A CN115711864 A CN 115711864A CN 202211457514 A CN202211457514 A CN 202211457514A CN 115711864 A CN115711864 A CN 115711864A
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gas
carbon dioxide
detection
exhaled
methane
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万志强
万江河
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Shandong Guoyu Biotechnology Co ltd
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Shandong Guoyu Biotechnology Co ltd
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Abstract

The invention discloses an exhaled gas gastrointestinal tract disease measuring system and method, belonging to the technical field of gastrointestinal tract disease measurement, wherein the measuring system comprises a microprocessor, a sample air bag, an air inlet pipe, a methane carbon dioxide laser detection mechanism, an air delivery pipe, a hydrogen detection mechanism, an exhaust pipe and a cleaning mechanism, wherein a constant temperature mechanism is arranged in the methane carbon dioxide laser detection mechanism, and the air delivery pipe is provided with an air inlet pump; the determination method comprises the steps of collecting exhaled gas, preheating a methane carbon dioxide laser detection mechanism, detecting the exhaled gas, processing detection data and cleaning a system after measurement. The gas content measuring instrument is simple in structure, scientific and reasonable in design and convenient to use, combines a traditional gas sensor and a laser gas sensor to measure the content of each gas in exhaled breath, and is high in measuring precision; the system is small in size and convenient to carry, the sample demand can be greatly reduced, the sampling difficulty is reduced, the breath measurement can be realized, the analysis time is short, and the measurement efficiency is greatly improved.

Description

Exhaled gas gastrointestinal tract disease determination system and method
Technical Field
The invention belongs to the technical field of gastrointestinal tract disease determination, and particularly relates to a system and a method for determining exhaled gastrointestinal tract diseases.
Background
The breath diagnosis technology for diagnosing the health condition of a human body by testing the composition of the exhaled gas of the human body has been rapidly developed in recent years. The gas exhaled by the human body contains much information which can reflect the health condition of the human body like the blood and urine of the human body. Experiments show that diseases such as small intestine bacterial overgrowth, methane-producing archaea, carbohydrate (sugar) intolerance and/or malabsorption, gastrointestinal transmission speed (time of mouth blindness), gastric acid secretion and the like can be found by simultaneously detecting the contents of methane, hydrogen and carbon dioxide in expiration.
At present, similar products enter into the breath diagnosis of clinical practical application at home and abroad, but in the breath test process, the collection of human alveolar gas cannot be carried out continuously in a large amount like environmental gas, so that the quantity of collected sample gas is very small, and the sample gas with small quantity and low concentration is very inconvenient to measure. The problem to be solved at present is that a gas chromatography-mass spectrometer is adopted to measure sample gas, the gas chromatography-mass spectrometer needs small sample amount and high measurement precision, but the gas chromatography-mass spectrometer has the following problems: firstly, the manufacturing cost is high, the operation and maintenance are complex, the cost is high, the equipment is huge and heavy, and the clinical popularization is not facilitated; secondly, the data analysis process is long in duration and low in efficiency.
Therefore, the invention provides a system and a method for determining exhaled breath gastrointestinal tract diseases, which solve the technical problems of low detection efficiency of exhaled breath or high cost of detection equipment and the like, and combine the traditional gas sensor and the laser gas sensor to determine the content of each gas in exhaled breath, so that the measurement precision is high; the system is small in size and convenient to carry, the sample demand can be greatly reduced, the sampling difficulty is reduced, the breath measurement can be realized, the analysis time is shortened to 15 seconds per sample, and the measurement efficiency is greatly improved.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: provides a system and a method for determining exhaled gas gastrointestinal tract diseases, and solves the technical problems of low exhaled gas detection efficiency or high cost of detection equipment and the like in the prior art.
In order to realize the purpose, the technical scheme adopted by the invention is as follows:
a gastrointestinal tract disease detecting system for exhaled breath comprises a microprocessor, at least one sample air bag for collecting and storing exhaled breath, an air inlet pipe connected with one sample air bag, a methane carbon dioxide laser detection mechanism connected with the air inlet pipe for detecting the contents of methane and carbon dioxide in the exhaled breath in one sample air bag, an air conveying pipe connected with the methane carbon dioxide laser detection mechanism, a hydrogen detection mechanism connected with the air conveying pipe for detecting the content of hydrogen in the exhaled breath in one sample air bag, an exhaust pipe connected with the hydrogen detection mechanism, and a cleaning mechanism connected with the air inlet pipe for cleaning the mechanisms after the completion, wherein a constant temperature mechanism is arranged in the methane carbon dioxide laser detection mechanism, an air inlet pump is arranged on the air conveying pipe, and the microprocessor is respectively connected with the methane carbon dioxide laser detection mechanism, the hydrogen detection mechanism, the constant temperature mechanism and the air inlet pump.
Furthermore, the air inlet pipe comprises an air inlet channel connected with the sample air bag and an air inlet main pipe connected with the air inlet channel, an air inlet electromagnetic valve and a switching electromagnetic valve are sequentially installed on the air inlet main pipe along the air flow direction, and the air inlet electromagnetic valve and the switching electromagnetic valve are respectively connected with the microprocessor.
Further, wiper mechanism connects out and inserts the washing gas input tube of being responsible for that admits air including the storage jar that stores the washing gas, from the storage jar, and the washing gas input tube is connected with the switching solenoid valve.
Further, methane carbon dioxide laser detection mechanism includes first detection chamber and locates laser methane sensor and the carbon dioxide sensor in the first detection chamber, and first detection chamber is responsible for from the admission and is connect out and insert the gas-supply pipe, and laser methane sensor and carbon dioxide sensor link to each other with microprocessor respectively.
Further, first detection chamber includes that the distribution of air current direction is followed and the first detection chamber A and the first detection chamber B that are linked together, and laser methane sensor is located first detection chamber A, and the carbon dioxide sensor is located first detection chamber B.
Furthermore, the constant temperature mechanism is arranged in the first detection cavity A and comprises a heater, a temperature sensor and a humidity sensor, and the heater, the temperature sensor and the humidity sensor are respectively connected with the microprocessor.
Further, the hydrogen detection mechanism comprises a second detection cavity and a hydrogen sensor arranged in the second detection cavity, the second detection cavity is connected out of the gas pipe and connected into the exhaust pipe, and the hydrogen sensor is connected with the microprocessor.
Further, the exhaust pipe is provided with an exhaust solenoid valve connected with the microprocessor.
An exhaled gastrointestinal disease assay method comprising the steps of:
step 1, collecting exhaled air by a sample air bag;
step 2, the microprocessor controls the constant temperature mechanism to preheat the methane carbon dioxide laser detection mechanism;
step 3, connecting the sample air bag to an air inlet pipe, controlling the air inlet pump to operate by the microprocessor, sequentially pumping exhaled air in the sample air bag into the methane carbon dioxide laser detection mechanism and the hydrogen detection mechanism for detection, and finally discharging the exhaled air through the exhaust pipe, wherein data in the methane carbon dioxide laser detection mechanism and the hydrogen detection mechanism are transmitted to the microprocessor in real time in the process;
step 4, the microprocessor calculates all the data to respectively obtain the concentrations of methane, carbon dioxide and hydrogen in the exhaled breath;
and 5, after the measurement is finished, opening the cleaning mechanism to convey cleaning gas, and cleaning each pipeline and each mechanism.
Further, in step 2, the purge gas is air or nitrogen.
Compared with the prior art, the invention has the following beneficial effects:
the gas content measuring instrument is simple in structure, scientific and reasonable in design and convenient to use, combines a traditional gas sensor and a laser gas sensor to measure the content of each gas in exhaled breath, and is high in measuring precision which can reach within 1 ppm; the system is small in size and convenient to carry, the sample demand can be greatly reduced, the sampling difficulty is reduced, the breath measurement can be realized, the analysis time is shortened to 15 seconds per sample, and the measurement efficiency is greatly improved.
The laser gas sensor is applied to the exhaled gas gastrointestinal tract disease detection, and has the characteristics of small volume, low manufacturing cost, low maintenance cost, linear output, low power consumption, high resolution, good repeatability, good accuracy and the like. The invention also carries out corresponding treatment on the interference gas in the exhaled breath, and adopts a constant temperature mechanism to carry out temperature and humidity compensation, thereby greatly reducing the measurement influence of the interference gas, and having high measurement precision and short measurement time.
Drawings
FIG. 1 is a schematic diagram of the present invention (microprocessor connections are not shown in detail).
FIG. 2 is a diagram of an embodiment of the present invention having multiple detection channels (the microprocessor connections are not shown in detail).
FIG. 3 is a structural diagram of a methane carbon dioxide laser detection mechanism according to the present invention.
FIG. 4 is a structural view of a hydrogen gas detecting mechanism according to the present invention.
FIG. 5 is a diagram of the connection of electrical devices according to the present invention.
Wherein, the names corresponding to the reference numbers are:
1-a sample air bag, 2-an air inlet pipe, 3-a methane carbon dioxide laser detection mechanism, 4-a cleaning mechanism, 5-an air inlet pipe, 6-a hydrogen detection mechanism, 7-an air outlet pipe, 8-a microprocessor, 9-a constant temperature mechanism, 10-an air inlet pump, 21-an air inlet channel, 22-an air inlet main pipe, 23-an air inlet electromagnetic valve, 24-a switching electromagnetic valve, 32-a laser methane sensor, 33-a carbon dioxide sensor, 34-a first detection cavity A, 35-a first detection cavity B, 41-a storage tank, 42-a cleaning gas input pipe, 61-a second detection cavity, 62-a hydrogen sensor, 71-an air outlet electromagnetic valve, 91-a heater, 92-a temperature sensor and 93-a humidity sensor.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the accompanying drawings. It should be apparent that the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation or be constructed and operated in a particular orientation, and thus, it should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; of course, mechanical connection and electrical connection are also possible; alternatively, they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood according to specific situations by those of ordinary skill in the art.
As shown in fig. 1-5, the system for determining gastrointestinal tract diseases by exhaled breath provided by the present invention comprises a microprocessor 8, at least one sample air bag 1 for collecting and storing exhaled breath, an air inlet tube 2 connected to one sample air bag 1, a methane carbon dioxide laser detection mechanism 3 connected to the air inlet tube 2 for respectively determining the contents of methane and carbon dioxide in exhaled breath, an air delivery tube 5 connected to the methane carbon dioxide laser detection mechanism 3, a hydrogen detection mechanism 6 connected to the air delivery tube 5 for determining the content of hydrogen in exhaled breath, an air outlet tube 7 connected to the hydrogen detection mechanism 6, and a cleaning mechanism 4 connected to the air inlet tube 2 for cleaning each mechanism after the completion, wherein a constant temperature mechanism 9 is arranged in the methane carbon dioxide laser detection mechanism 3, an air inlet pump 10 is arranged on the air delivery tube 5, and the microprocessor 8 is respectively connected to the methane carbon dioxide laser detection mechanism 3, the hydrogen detection mechanism 6, the constant temperature mechanism 9, and the air inlet pump 10. The invention solves the technical problems of low detection efficiency or high cost of detection equipment of the existing exhaled gas, combines the traditional gas sensor and the laser gas sensor to be used for determining the content of each gas in the exhaled gas, and has high measurement precision; the system is small in size and convenient to carry, the sample demand can be greatly reduced, the sampling difficulty is reduced, the breath measurement can be realized, the analysis time is shortened to 15 seconds per sample, and the measurement efficiency is greatly improved.
In order to further increase the detection efficiency, the present invention has at least one sample gas bag 1 for collecting and storing exhaled breath, and in some embodiments, the present invention is configured as a multiple sample channel, i.e., a plurality of sample gas bags 1. Every sample air pocket 1 has solitary measuring channel, is connected with corresponding intake pipe 2, methane carbon dioxide laser detection mechanism 3 and hydrogen detection mechanism 6, reaches the demand of many samples key operation simultaneous measurement, has reduced the artifical input cost greatly, has reduced the sampling degree of difficulty.
The air inlet pipe 2 comprises an air inlet channel 21 connected with the sample air bag 1 and an air inlet main pipe 22 connected with the air inlet channel 21, wherein an air inlet electromagnetic valve 23 and a switching electromagnetic valve 24 are sequentially arranged on the air inlet main pipe 22 along the air flow direction, and the air inlet electromagnetic valve 23 and the switching electromagnetic valve 24 are respectively connected with the microprocessor 8. The microprocessor 8 controls the air inlet electromagnetic valve 23 to input the expired air in the sample air bag 1 into the air inlet main pipe 22 through the air inlet channel 21, and the detection operation is started.
The cleaning mechanism 4 of the present invention includes a storage tank 41 for storing cleaning gas, and a cleaning gas input pipe 42 connected to the main gas inlet pipe 22 and connected from the storage tank 41, and the cleaning gas input pipe 42 is connected to the switching solenoid valve 24. The cleaning mechanism 4 can clean each mechanism and each pipeline after the detection is finished, and subsequent detection errors caused by the residual of the previous expired air are avoided. The purge gas stored in the storage tank 41 is nitrogen gas or filtered clean air. The microprocessor 8 controls the switching solenoid valve 24 to input the cleaning gas in the tank 41 from the inlet passage 21 into the inlet main pipe 22, and the cleaning operation is started.
The methane and carbon dioxide laser detection mechanism 3 comprises a first detection cavity, and a laser methane sensor 32 and a carbon dioxide sensor 33 which are arranged in the first detection cavity, wherein the first detection cavity is connected out of the air inlet main pipe 22 and is connected into the air conveying pipe 5, and the laser methane sensor 32 and the carbon dioxide sensor 33 are respectively connected with the microprocessor 8. The methane and carbon dioxide laser detection mechanism 3 can respectively detect methane and carbon dioxide in the exhaled breath. Methane is used as an important index for gastrointestinal tract disease diagnosis, the measurement accuracy of the methane greatly affects the diagnosis result, the laser methane sensor 32 is a sensor of a laser absorption spectrum method, the infrared absorption of the methane sensor is different from the infrared absorption of the traditional methane sensor, the laser absorption is selective to methane, the methane is not interfered by other various gases or water vapor, the influence of other interfering gases in exhaled air is avoided, and the measurement accuracy is greatly enhanced.
Because laser methane detects and receives the influence of environment humiture easily, and then causes the inaccurate problem of measurement, the detection condition of this methane is comparatively harsh. The invention separates the detection areas of methane and carbon dioxide, thereby reducing detection errors. Preferably, the first detection cavity 21 includes a first detection cavity a34 and a first detection cavity B35 which are distributed along the gas flow direction and are communicated with each other, the laser methane sensor 32 is located in the first detection cavity a34, and the carbon dioxide sensor 33 is located in the first detection cavity B35. The exhaled breath flows through the first detection chamber a34 and the first detection chamber B35 in this order to perform separate detection of methane and carbon dioxide.
In order to reduce the influence of the temperature and the humidity on the methane detection, the temperature and the humidity are compensated through the constant temperature mechanism 9. The constant temperature mechanism 9 is arranged in the first detection cavity A34 and comprises a heater 91, a temperature sensor 92 and a humidity sensor 93, the heater 91 can maintain the environment in the first detection cavity A34 at the optimal detection temperature of methane, and preferably, the heating temperature of the heater 91 is set to 35 ℃, so that the temperature and humidity compensation is correspondingly carried out, and the accuracy of methane concentration detection is ensured. And the temperature and humidity data in the detection environment are recorded in real time through the temperature sensor 92 and the humidity sensor 93, and are fed back to the microprocessor 8 for the temperature and humidity compensation calculation of the subsequent methane concentration.
Hydrogen is also an important indicator for the diagnosis of gastrointestinal disorders. The hydrogen detection mechanism 6 comprises a second detection cavity 61 and a hydrogen sensor 62 arranged in the second detection cavity 61, the second detection cavity 61 is connected out from the gas pipe 5 and connected into the exhaust pipe 7, and the hydrogen sensor 62 is connected with the microprocessor 8. The expired gas detected by the methane carbon dioxide laser detection mechanism 3 reaches the hydrogen detection mechanism 6 to be detected in the hydrogen concentration, and is finally discharged by the exhaust pipe 7. Preferably, the exhaust pipe 7 is provided with an exhaust solenoid valve 71 connected to the microprocessor 8, the microprocessor 8 controls the exhaust solenoid valve 71 to open to form an exhaust passage only when detecting operation is performed, and the exhaust solenoid valve 71 is a one-way valve to prevent external air from flowing back into the system.
An exhaled breath gastrointestinal disorder measurement system comprising the steps of:
step 1, collecting exhaled air by a sample air bag;
step 2, the microprocessor controls the constant temperature mechanism to preheat the methane carbon dioxide laser detection mechanism;
step 3, connecting the sample air bag to an air inlet pipe, controlling the air inlet pump to operate by the microprocessor, sequentially pumping exhaled air in the sample air bag into the methane carbon dioxide laser detection mechanism and the hydrogen detection mechanism for detection, and finally discharging the exhaled air through an exhaust pipe, wherein in the process, data in the methane carbon dioxide laser detection mechanism and the hydrogen detection mechanism are transmitted to the microprocessor in real time;
step 4, the microprocessor calculates all data to respectively obtain the concentrations of methane, carbon dioxide and hydrogen in the exhaled breath;
and 5, after the measurement is finished, opening a cleaning mechanism to convey cleaning gas, and cleaning each pipeline and each mechanism.
In the step 1, the collection of the exhaled breath is performed by mouth blowing, and the sample air bag is preferably configured to have a blowing port and a gas transmission port. The air blowing port is used for blowing and collecting the exhaled air and is screwed up and sealed through the sealing screw cap, the air conveying port is used for being connected with the air inlet pipe, the air conveying port is also provided with a sealing cover, the air input and the air output are separated, the operation is convenient, and the sanitation and cleanness are also ensured. When the detection is needed, the sealing cover of the air transmission port is opened rapidly to insert the air transmission port on the air inlet pipe in a sealing manner. The collection capacity of the expired air of the sample air bag is not lower than 100ML.
And in the step 3, the measurement data of the laser methane sensor and the carbon dioxide sensor of the methane and carbon dioxide laser detection mechanism and the temperature and humidity data of the temperature sensor and the humidity sensor are transmitted to the microprocessor in real time, and the hydrogen sensor of the hydrogen detection mechanism is transmitted to the microprocessor in real time.
In the step 4, the microprocessor processes the measured data of the carbon dioxide and the hydrogen to obtain the concentrations of the carbon dioxide and the hydrogen in the exhaled air respectively, and the measured data of the methane needs to be subjected to temperature and humidity compensation calculation and reprocessed according to the temperature and humidity data to obtain the concentration of the methane in the exhaled air. And then further analyzing the concentration of each gas to judge whether gastrointestinal diseases exist.
In the step 4, since a large amount of exhaled air remains in the system after the measurement is finished, the system is cleaned by a cleaning mechanism to avoid affecting the next measurement, and the cleaning air is pumped in by an air inlet pump and then discharged from an exhaust pipe. The cleaning gas is air or nitrogen, wherein the air is clean air after filtration treatment.
The invention can also be externally connected with a liquid crystal display screen through an interface, and the liquid crystal display screen is connected with the microprocessor and is used for displaying each measurement data, temperature and humidity data and finally the concentration of each measurement gas.
The microprocessor 8 of the present invention is preferably STM32F103ZE, and the liquid crystal display screen, the air intake pump 10, the air intake solenoid valve 23, the switching solenoid valve 24, the laser methane sensor 32, the carbon dioxide sensor 33, the hydrogen sensor 62, the air exhaust solenoid valve 71, the heater 91, the temperature sensor 92 and the humidity sensor 93 used in the microprocessor are all known electrical devices, and all of them can be purchased and used directly on the market, and their structures, circuits and control principles are known in the prior art, and therefore, the structures, circuits and control principles of the liquid crystal display screen, the air intake pump 10, the air intake solenoid valve 23, the switching solenoid valve 24, the laser methane sensor 32, the carbon dioxide sensor 33, the hydrogen sensor 62, the air exhaust solenoid valve 71, the heater 91, the temperature sensor 92 and the humidity sensor 93 are not described in detail herein.
Finally, it should be noted that: the above embodiments are only preferred embodiments of the present invention to illustrate the technical solutions of the present invention, but not to limit the technical solutions, and certainly not to limit the patent scope of the present invention; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention; that is, the technical problems to be solved by the present invention, which are not substantially changed or supplemented by the spirit and the concept of the main body of the present invention, are still consistent with the present invention and shall be included in the scope of the present invention; in addition, the technical scheme of the invention is directly or indirectly applied to other related technical fields, and the technical scheme is included in the patent protection scope of the invention.

Claims (10)

1. The exhaled gas gastrointestinal tract disease detection system is characterized by comprising a microprocessor (8), at least one sample air bag (1) for collecting and storing exhaled gas, a gas inlet pipe (2) connected with the sample air bag (1), a methane carbon dioxide laser detection mechanism (3) connected with the gas inlet pipe (2) and used for measuring the content of methane and carbon dioxide in the exhaled gas in the sample air bag (1), a gas conveying pipe (5) connected with the methane carbon dioxide laser detection mechanism (3), a hydrogen detection mechanism (6) connected with the gas conveying pipe (5) and used for measuring the content of hydrogen in the exhaled gas in the sample air bag (1), an exhaust pipe (7) connected with the hydrogen detection mechanism (6), and a cleaning mechanism (4) connected with the gas inlet pipe (2) and used for cleaning the mechanisms after the cleaning are finished, wherein a constant temperature mechanism (9) is arranged in the methane carbon dioxide laser detection mechanism (3), a gas conveying pipe (5) is provided with a gas inlet pump (10), and the microprocessor (8) is respectively connected with the methane carbon dioxide laser detection mechanism (3), the hydrogen detection mechanism (6), the constant temperature mechanism (9) and the gas inlet pump (10).
2. The exhaled gastrointestinal tract disease measurement system according to claim 1, wherein the air intake tube (2) comprises an air intake channel (21) connected to the sample air bag (1), and an air intake main tube (22) connected to the air intake channel (21), the air intake main tube (22) is sequentially provided with an air intake solenoid valve (23) and a switching solenoid valve (24) along an air flow direction, and the air intake solenoid valve (23) and the switching solenoid valve (24) are respectively connected to the microprocessor (8).
3. The system according to claim 2, wherein the purge mechanism (4) comprises a storage tank (41) for storing a purge gas, and a purge gas inlet pipe (42) connected to the main intake pipe (22) and connected to the storage tank (41), and the purge gas inlet pipe (42) is connected to the switching solenoid valve (24).
4. The exhaled gas gastrointestinal tract disease measurement system according to claim 2, wherein the methane carbon dioxide laser detection mechanism (3) comprises a first detection cavity, and a laser methane sensor (32) and a carbon dioxide sensor (33) which are arranged in the first detection cavity, the first detection cavity is connected out of the gas inlet main pipe (22) and is connected into the gas pipe (5), and the laser methane sensor (32) and the carbon dioxide sensor (33) are respectively connected with the microprocessor (8).
5. An exhaled breath gastrointestinal disorder measuring system according to claim 4, wherein the first detection chamber (21) comprises a first detection chamber A (34) and a first detection chamber B (35) which are distributed along the direction of the gas flow and are communicated with each other, the laser methane sensor (32) is located in the first detection chamber A (34), and the carbon dioxide sensor (33) is located in the first detection chamber B (35).
6. The exhaled gastrointestinal tract disease measurement system according to claim 5, wherein the thermostatic mechanism (9) is provided in the first detection chamber A (34) and comprises a heater (91), a temperature sensor (92) and a humidity sensor (93), and the heater (91), the temperature sensor (92) and the humidity sensor (93) are respectively connected to the microprocessor (8).
7. An exhaled breath gastrointestinal disease detection system according to claim 1, wherein the hydrogen detection mechanism (6) comprises a second detection chamber (61) and a hydrogen sensor (62) arranged in the second detection chamber (61), the second detection chamber (61) is connected to the gas pipe (5) and connected to the gas exhaust pipe (7), and the hydrogen sensor (62) is connected to the microprocessor (8).
8. An exhaled breath gastrointestinal disorder detection system according to claim 1, wherein the exhaust line (7) is fitted with an exhaust solenoid valve (71) connected to the microprocessor (8).
9. A method for determining exhaled gastrointestinal disease comprising the steps of:
step 1, collecting exhaled breath by a sample air bag;
step 2, the microprocessor controls the constant temperature mechanism to preheat the methane carbon dioxide laser detection mechanism;
step 3, connecting the sample air bag to an air inlet pipe, controlling the air inlet pump to operate by the microprocessor, sequentially pumping exhaled air in the sample air bag into the methane carbon dioxide laser detection mechanism and the hydrogen detection mechanism for detection, and finally discharging the exhaled air through the exhaust pipe, wherein data in the methane carbon dioxide laser detection mechanism and the hydrogen detection mechanism are transmitted to the microprocessor in real time in the process;
step 4, the microprocessor calculates all the data to respectively obtain the concentrations of methane, carbon dioxide and hydrogen in the exhaled breath;
and 5, after the measurement is finished, opening the cleaning mechanism to convey cleaning gas, and cleaning each pipeline and each mechanism.
10. The method of claim 9, wherein in step 2, the purge gas is air or nitrogen.
CN202211457514.0A 2022-11-21 2022-11-21 Exhaled gas gastrointestinal tract disease determination system and method Withdrawn CN115711864A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116660509A (en) * 2023-06-01 2023-08-29 青岛瑞谱乐医疗科技有限公司 Exhaled gas detection method
CN116660510A (en) * 2023-06-01 2023-08-29 青岛瑞谱乐医疗科技有限公司 Expired gas detection device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116660509A (en) * 2023-06-01 2023-08-29 青岛瑞谱乐医疗科技有限公司 Exhaled gas detection method
CN116660510A (en) * 2023-06-01 2023-08-29 青岛瑞谱乐医疗科技有限公司 Expired gas detection device

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