CN115698249A - 样本前处理系统 - Google Patents

样本前处理系统 Download PDF

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Publication number
CN115698249A
CN115698249A CN202080102113.6A CN202080102113A CN115698249A CN 115698249 A CN115698249 A CN 115698249A CN 202080102113 A CN202080102113 A CN 202080102113A CN 115698249 A CN115698249 A CN 115698249A
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module
container
sample
cover
pipetting
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高建东
李景
孙强
赵学江
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MGI Tech Co Ltd
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MGI Tech Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B25HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25JMANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
    • B25J11/00Manipulators not otherwise provided for
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/22Means for packing or storing viable microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34Purifying; Cleaning
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0403Sample carriers with closing or sealing means
    • G01N2035/0405Sample carriers with closing or sealing means manipulating closing or opening means, e.g. stoppers, screw caps, lids or covers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0406Individual bottles or tubes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0418Plate elements with several rows of samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Robotics (AREA)
  • Clinical Laboratory Science (AREA)
  • Computer Hardware Design (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

一种样本前处理系统(1),包括样本存储模块(10)、样本转移模块(20)、脱合盖模块(30)、传输模块(40)、移液模块(50)和控制模块。样本存储模块(10)存储装载有生物样本的容器(2)。样本转移模块(20)抓取位于样本存储模块(10)的容器(2)并转移至传输模块(40)上。传输模块(40)将容器(2)分别传输至脱合盖模块(30)以及移液模块(50)。脱合盖模块(30)对传输模块(40)上的容器(2)的识别码进行扫描,还将容器(2)的盖体(202)与容器(2)本体分离。移液模块(50)将传输模块(40)上容器(2)内的生物样本进行分杯。脱合盖模块(30)还在生物样本被分杯后,将抓取的盖体(202)重新盖合于传输模块(40)上的容器本体(201)上。样本转移模块(20)还在盖体(202)被重新盖合后,将传输模块(40)上的容器(2)转移回样本存储模块(10)。控制模块控样本转移模块(20)、脱合盖模块(30)、传输模块(40)和移液模块(50)协同作业。

Description

PCT国内申请,说明书已公开。

Claims (15)

  1. PCT国内申请,权利要求书已公开。
CN202080102113.6A 2020-07-23 2020-07-23 样本前处理系统 Pending CN115698249A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2020/103896 WO2022016475A1 (zh) 2020-07-23 2020-07-23 样本前处理系统

Publications (1)

Publication Number Publication Date
CN115698249A true CN115698249A (zh) 2023-02-03

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CN202080102113.6A Pending CN115698249A (zh) 2020-07-23 2020-07-23 样本前处理系统

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Country Link
US (1) US20230288441A1 (zh)
EP (1) EP4186970A4 (zh)
CN (1) CN115698249A (zh)
WO (1) WO2022016475A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114733589A (zh) * 2022-03-03 2022-07-12 济南市疾病预防控制中心 一种自动移液站
CN114887680A (zh) * 2022-05-05 2022-08-12 耐优生物技术(嘉兴)有限公司 一种基于文本识别的移液方案构建方法
CN114935662A (zh) * 2022-07-21 2022-08-23 湖南慧泽生物医药科技有限公司 一体化生物样品处理系统

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
EP2538225A1 (en) * 2011-06-20 2012-12-26 F. Hoffmann-La Roche AG System for processing closed sample tubes
CN107255731A (zh) * 2011-09-09 2017-10-17 简·探针公司 自动化样品处理仪器、系统、过程和方法
CN108738348B (zh) * 2016-02-17 2023-09-01 贝克顿·迪金森公司 用于相同的诊断测试的自动化样品制备系统
CN105865870B (zh) * 2016-04-12 2018-07-10 曹汝安 标本预处理设备
US11199560B2 (en) * 2016-04-22 2021-12-14 Becton Dickinson And Company Automated diagnostic analyzer and method for its operation
JP7118901B2 (ja) * 2016-06-20 2022-08-16 ジェネシス テクノロジーズ リミティド 自動化された細胞加工システム及び方法
CN106367343B (zh) * 2016-08-29 2018-09-21 杭州键一生物科技有限公司 一种全自动智能细胞培养装置及其控制方法
WO2018053783A1 (zh) * 2016-09-23 2018-03-29 深圳华大智造科技有限公司 一种用于制备基因测序样本的系统及其应用
CN108408670B (zh) * 2017-02-10 2020-02-07 深圳华大智造科技有限公司 开盖装置及开盖系统
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CN208995474U (zh) * 2018-10-25 2019-06-18 威海百博医疗智能机器人有限公司 开盖装置
CN109342140A (zh) * 2018-10-30 2019-02-15 济南百博生物技术股份有限公司 一种高效微生物样本前处理系统
CN110579389B (zh) * 2019-11-08 2020-03-13 烟台艾德康生物科技有限公司 一种全自动样本前处理系统

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US20230288441A1 (en) 2023-09-14
EP4186970A1 (en) 2023-05-31
WO2022016475A1 (zh) 2022-01-27
EP4186970A4 (en) 2024-03-20

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