CN115697998A - 一种具有大范围斯托克斯位移的新型荧光化合物 - Google Patents

一种具有大范围斯托克斯位移的新型荧光化合物 Download PDF

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Publication number
CN115697998A
CN115697998A CN202180042636.0A CN202180042636A CN115697998A CN 115697998 A CN115697998 A CN 115697998A CN 202180042636 A CN202180042636 A CN 202180042636A CN 115697998 A CN115697998 A CN 115697998A
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fluorescent compound
group
solution
stokes shift
compound
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CN202180042636.0A
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陈锦森
张有福
李竑
王建鹏
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Nanjing Jinsirui Science and Technology Biology Corp
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Nanjing Jinsirui Science and Technology Biology Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

本发明涉及荧光染料领域，具体涉及一种具有大范围斯托克斯位移的新型荧光化合物，所述荧光化合物可用于核酸和多肽修饰，且斯托克斯位移最大可达到约190nm，即最大发射波长与最大激发波长有了较大波长差，从而解决了测量中因串扰以及后向散射效应带来的自淬灭和测量误差的问题。

Description

PCT国内申请，说明书已公开。

Claims (25)

  1. PCT国内申请，权利要求书已公开。
CN202180042636.0A 2020-06-15 2021-06-15 一种具有大范围斯托克斯位移的新型荧光化合物 Pending CN115697998A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2020105406040 2020-06-15
CN202010540604 2020-06-15
PCT/CN2021/100087 WO2021254321A1 (zh) 2020-06-15 2021-06-15 一种具有大范围斯托克斯位移的新型荧光化合物

Publications (1)

Publication Number Publication Date
CN115697998A true CN115697998A (zh) 2023-02-03

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CN202180042636.0A Pending CN115697998A (zh) 2020-06-15 2021-06-15 一种具有大范围斯托克斯位移的新型荧光化合物

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CN (1) CN115697998A (zh)
WO (1) WO2021254321A1 (zh)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE519172C2 (sv) * 2000-06-07 2003-01-21 Lightup Technologies Ab Fastfas syntes av cyaninfärgämnen
US7776567B2 (en) * 2005-03-17 2010-08-17 Biotium, Inc. Dimeric and trimeric nucleic acid dyes, and associated systems and methods

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WO2021254321A1 (zh) 2021-12-23

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