CN115683792A - Position adjusting mechanism, dyeing device and push sheet dyeing machine - Google Patents

Position adjusting mechanism, dyeing device and push sheet dyeing machine Download PDF

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Publication number
CN115683792A
CN115683792A CN202110877372.2A CN202110877372A CN115683792A CN 115683792 A CN115683792 A CN 115683792A CN 202110877372 A CN202110877372 A CN 202110877372A CN 115683792 A CN115683792 A CN 115683792A
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China
Prior art keywords
positioning
dyeing
staining
unit
cassette
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CN202110877372.2A
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Chinese (zh)
Inventor
胡国松
华德运
卢江涛
吴照栋
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Shenzhen Reetoo Biotechnology Co Ltd
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Shenzhen Reetoo Biotechnology Co Ltd
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Priority to CN202110877372.2A priority Critical patent/CN115683792A/en
Publication of CN115683792A publication Critical patent/CN115683792A/en
Pending legal-status Critical Current

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Abstract

The application provides a positioning mechanism, dyeing apparatus and push jack dyeing machine, positioning mechanism includes: a first power unit; the stopping piece is connected with the first power unit, so that the first power unit drives the stopping piece to move to a conveying path of the dyeing box, and the dyeing box is provided with a first positioning part; the positioning unit is provided with a second positioning part, the second positioning part is used for being matched with the first positioning part, the position accuracy of the dyeing box is improved, and the dyeing liquid is prevented from being injected into the dyeing box to fail, so that the dyeing failure is caused.

Description

Position adjusting mechanism, dyeing device and push sheet dyeing machine
Technical Field
The application relates to the technical field of medical instruments, in particular to a position adjusting mechanism, a dyeing device and a push piece dyeing machine.
Background
In the disease diagnosis and treatment, a sample is coated on a glass slide, and then microscopic detection is carried out to obtain a detection result, so that a reference basis is provided for a doctor to diagnose the disease. For example, microscopic examination of blood smears is a basic method for blood cytology, has wide application, and especially has great value in diagnosis of various blood diseases.
Before a sample is detected, the sample is usually required to be dyed, a slide coated with the sample is generally placed in a dyeing box, and then a dyeing solution is injected into the dyeing box, so that the dyeing box is required to be positioned, and the situation that the dyeing solution cannot be injected to cause dyeing failure is prevented.
Disclosure of Invention
This application mainly provides a positioning mechanism, dyeing apparatus and push jack dyeing machine, improves the position accuracy of dyeing box, avoids the dye liquor to pour into the failure, and then leads to the condition of dyeing failure.
In order to solve the technical problem, the application adopts a technical scheme that: there is provided a positioning mechanism comprising: a first power unit; the stopping piece is connected with the first power unit, so that the first power unit drives the stopping piece to move to a conveying path of a dyeing box, and the dyeing box is provided with a first positioning part; and the positioning unit is provided with a second positioning part which is used for being matched with the first positioning part.
In order to solve the above technical problem, another technical solution adopted by the present application is: the dyeing device comprises a transmission unit and the positioning mechanism, wherein the transmission unit is used for conveying the dyeing box, so that the slide in the dyeing box is dyed on the transmission unit.
In order to solve the above technical problem, the present application adopts another technical solution: the slide-pushing dyeing machine comprises a slide-pushing device and the dyeing device, wherein the slide-pushing device is used for coating a sample on the slide.
The beneficial effect of this application is: different from the situation of the prior art, the positioning mechanism provided by the application comprises: a first power unit; the stopping piece is connected with the first power unit, so that the first power unit drives the stopping piece to move to a conveying path of the dyeing box, and the dyeing box is provided with a first positioning part; the positioning unit is provided with a second positioning part, the second positioning part is used for being matched with the first positioning part, the position accuracy of the dyeing box is improved, and the dyeing liquid is prevented from being injected into the dyeing box to fail, so that the dyeing failure is caused.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the description below are only some embodiments of the present application, and it is obvious for those skilled in the art that other drawings may be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic perspective view of an embodiment of a dyeing apparatus provided herein;
FIG. 2 is a schematic block diagram of one embodiment of the dyeing apparatus of FIG. 1;
FIG. 3 is a schematic block diagram of another embodiment of the dyeing apparatus of FIG. 1;
FIG. 4 is a schematic block diagram of another embodiment of the dyeing apparatus of FIG. 1;
FIG. 5 is a schematic perspective view of an embodiment of the first transmission unit of FIG. 1;
FIG. 6 is a schematic perspective view of the first drive mechanism of FIG. 5;
FIG. 7 is a schematic front view of the bracket of FIG. 5;
FIG. 8 is a perspective view of the carriage mechanism of FIG. 5;
FIG. 9 is a schematic perspective view of another embodiment of the first transport unit of FIG. 1;
FIG. 10 is a schematic front view of an embodiment of the stand of FIG. 9;
FIG. 11 is a schematic front view of another embodiment of the bracket of FIG. 9;
FIG. 12 is a perspective view of the support mechanism of FIG. 9;
FIG. 13 is a schematic front view of the carriage mechanism of FIG. 12 assembled with the bracket of FIG. 11;
fig. 14 is a schematic perspective view of a second transmission unit provided in the present application;
FIG. 15 is a schematic perspective view of an embodiment of the positioning mechanism of FIG. 1;
FIG. 16 is a schematic perspective view of the dyeing cassette of FIG. 1;
FIG. 17 is an enlarged schematic view of section E of FIG. 15;
FIG. 18 is a schematic perspective view of another embodiment of the positioning mechanism of FIG. 1;
FIG. 19 is a schematic view of the positioning unit of FIG. 18 in a state of being released from the positioning;
FIG. 20 is a schematic view of the positioning state of the positioning unit in FIG. 18;
figure 21 is a perspective view of an embodiment of a push piece dyeing machine provided herein;
FIG. 22 is a schematic block diagram of the push piece dyeing machine of FIG. 21;
fig. 23 is a schematic flow diagram of an embodiment of a dyeing method provided herein.
Detailed Description
The present application is described in further detail below with reference to the accompanying drawings and embodiments. In particular, the following embodiments are merely illustrative of the present application, and do not limit the scope of the present application. Likewise, the following embodiments are only some embodiments of the present application, not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present application.
The terms "first", "second" and "third" in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or as implying a number of indicated technical features. Thus, a feature defined as "first," "second," or "third" may explicitly or implicitly include at least one of the feature. In the description of this application, "plurality" means at least two, in a manner such as two, three, etc., unless specifically limited otherwise. All directional indicators in the embodiments of the present application (such as up, down, left, right, front, rear \8230;) are only used to explain the relative positional relationship between the components, the motion, etc. at a particular attitude (as shown in the drawings), and if the particular attitude changes, the directional indicator changes accordingly. Furthermore, the terms "comprising" and "having," as well as any variations thereof, are intended to cover non-exclusive inclusions. A process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
Referring to fig. 1, fig. 2 and fig. 3 together, fig. 1 is a schematic perspective view of an embodiment of a staining apparatus 10 provided in the present application, and fig. 2 is a schematic block diagram of an embodiment of the staining apparatus 10 in fig. 1, in which the staining apparatus 10 in the present embodiment includes a slide receiving area R1, a first staining area R2 and a staining box transmission area R3 connected end to end in sequence.
The slide receiving area R1 and the staining box transmission area R3 are respectively provided with a first transmission unit 11, and the first staining area R2 is provided with a second transmission unit 12.
Further, the first transfer unit 11 in the slide receiving area R1 is configured to transfer the staining cassette 120 after receiving the slide 110 to the first staining area R2, specifically, the staining cassette 120 is transferred to the slide receiving area R1 when the slide 110 is not loaded, then the staining cassette 120 receives the slide 110 gripped by the slide gripping mechanism, and finally the first transfer unit 11 in the slide receiving area R1 transfers the staining cassette 120 after receiving the slide 110 to the first staining area R2 along the transfer direction A1, so that the slide 110 is stained in the first staining area R2.
The second transfer unit 12 in the first staining region R2 is configured to transfer the staining cassette 120 to the staining cassette transfer region R3, specifically, the second transfer unit 12 in the first staining region R2 receives the staining cassette 120 after receiving the slide 110 transferred from the slide receiving region R1, and when the slide 110 is completely stained in the first staining region R2, the second transfer unit 12 in the first staining region R2 transfers the staining cassette 120 to the staining cassette transfer region R3 along the transfer direction B1.
The first transport unit 11 in the staining cassette transport region R3 is configured to transport the staining cassette 120 to the slide receiving region R1, and specifically, the first transport unit 11 in the staining cassette transport region R3 receives the staining cassette 120 transported from the first staining region R2, then transports the staining cassette 120 to the slide receiving region R1 along the transport direction C1, and finally, as described above, the staining cassette in the slide receiving region R1 receives the slide 110 again, and the above cycle is repeated, so that the staining cassette 120 can be reused, without manual operation, the degree of automation is high, the whole device layout is reasonable, and the space utilization rate of the instrument is high.
Referring to fig. 3, fig. 3 is a schematic block diagram of another embodiment of the staining apparatus 10 in fig. 1, wherein in the another embodiment, the staining apparatus 10 further includes a second staining region R4, a second transmission unit 12 is disposed in the second staining region R4, the slide receiving region R1, the first staining region R2, the staining cassette transmission region R3, and the second staining region R4 are sequentially connected end to end, the first transmission unit 11 of the staining cassette transmission region R3 is configured to transmit the staining cassette 120 to the second staining region R4, and the second transmission unit 12 of the second staining region R4 is configured to transmit the staining cassette 12 to the slide receiving region R1.
Specifically, after the first transport unit 11 of the slide receiving area R1 transports the staining cassette 120 after receiving the slide 110 to the first staining area R2 along the transport direction a21, the slide 110 is partially stained in the first staining area R2, then the second transport unit 12 of the first staining area R2 transports the staining cassette 120 to the staining cassette transport area R3 along the transport direction B21, the first transport unit 11 of the staining cassette transport area R3 transports the staining cassette 120 to the second staining area R4 along the transport direction a22, so that the slide 110 completes another partial staining in the second staining area R4, so that the slide 110 completes the complete staining, and after the slide 110 completes the complete staining, the slide 110 is taken away by the slide gripper, at this time, the second transport unit 12 of the second staining area R4 transports the empty staining cassette 120 to the slide receiving area R1 again along the transport direction B22, so that the slide cassette 120 can be reused.
It can be understood that, since many samples, such as blood samples, are stained more, in the above another embodiment, by the arrangement of the first staining region R2 and the second staining region R4, not only the recycling of the staining cassette 120 is achieved, but also the situation that if all staining is performed in one staining region, the length of the staining region in the layout is longer, and the occupied space of the whole apparatus is larger is avoided.
Referring to fig. 4, fig. 4 is a schematic block diagram of another embodiment of the dyeing apparatus 10 in fig. 1, in the another embodiment, the staining cassette transmission area R3 includes a first staining cassette transmission area R31 and a second staining cassette transmission area R32, the slide receiving area R1, the first staining cassette transmission area R2, the first staining cassette transmission area R31 and the second staining cassette transmission area R2 are sequentially connected end to end, the first staining cassette transmission area R31 is provided with a first transmission unit 11, the second staining cassette transmission area R32 is provided with a second transmission unit 12, the second transmission unit 12 of the first staining cassette transmission area R2 is used for transmitting the staining cassette 120 to the first staining cassette transmission area R31, the first transmission unit 11 of the first staining cassette transmission area 31 is used for transmitting the staining cassette 120 to the second staining cassette transmission area R32, and the second transmission unit 12 of the second staining cassette transmission area R32 is used for transmitting the staining cassette 120 to the slide receiving area R1.
Specifically, after the first transfer unit 11 of the slide receiving area R1 transfers the staining cassette 120 after receiving the slide 110 to the first staining area R2 along the transfer direction a21, the slide 110 is stained in the first staining area R2, after the slide staining is completed, the slide 110 is taken away from the staining cassette 120 by the slide clamping mechanism, then the second transfer unit 12 of the first staining area R2 transfers the empty staining cassette 120 to the first staining cassette transfer area R31 along the transfer direction B21, the first transfer unit 11 of the first staining cassette transfer area R31 transfers the empty staining cassette 120 to the second staining cassette transfer area R32 along the transfer direction B22, and the second transfer unit 12 of the second staining cassette transfer area R32 transfers the empty staining cassette 120 to the slide receiving area R1 along the transfer direction B22, so that the staining cassette 120 can be reused.
Referring to fig. 5-8 together, fig. 5 is a schematic perspective view illustrating an embodiment of the first transmission unit 11 in fig. 1, fig. 6 is a schematic perspective view illustrating the first driving mechanism 111 in fig. 5, fig. 7 is a schematic front view illustrating the bracket 113 in fig. 5, and fig. 8 is a schematic perspective view illustrating the carrying mechanism 112 in fig. 5.
For example, in the above-mentioned another embodiment, the height of the first staining cassette receiving end of the slide receiving area R1 in the vertical direction is smaller than the height of the second staining cassette ejecting end of the second staining area R4, so as to reduce the difficulty of the slide receiving area R1 receiving the staining cassette 120 transmitted from the second staining area R4, and the height of the first staining cassette ejecting end of the slide receiving area R1 in the vertical direction is greater than the height of the second staining cassette receiving end of the first staining area R2, so as to reduce the difficulty of the first staining area R2 receiving the staining cassette 120 transmitted from the slide receiving area R1.
The first transmission unit 11 includes a first driving mechanism 111 and a carrying mechanism 112, the dyeing box 120 is carried on the carrying mechanism 112, and the first driving mechanism 111 is connected to the carrying mechanism 112 for transmitting the dyeing box 120.
The first driving mechanism 111 includes a first motor 1111, a first driving wheel 1112, a plurality of first driven wheels 1113 and a first transmission belt 1114, the first driving wheel 1112 is disposed on an output shaft of the first motor 1111, the first transmission belt 1114 is connected to the carrying mechanism 112 and respectively wound around the first driving wheel 1112 and the plurality of first driven wheels 1113, so that the first transmission belt 1114 is disposed in a polygon shape.
Optionally, the first driving mechanism 111 further includes a first tensioning wheel 1115, and the first tensioning wheel 1115 is pressed on the first conveyor belt 1114 to increase the tensioning degree of the first conveyor belt 1114.
Further, the carrying mechanism 112 is provided with a first carrying portion 112a, the first carrying portion 112a includes a first carrying body 1121 and a second carrying body 1122, the first carrying body 1121 and the second carrying body 1122 are disposed in an inclined manner relative to the second carrying body 1122, so as to form a carrying groove 1123 as shown in fig. 8, and the dyeing box 120 is carried in the carrying groove 1123, so as to improve the stability of the transportation process of the dyeing box 120.
Further, the first transmission unit 11 further includes a bracket 113, and the first driving mechanism 111 is mounted on the bracket 113.
The bracket 113 includes a first guiding surface 1131, and the first guiding surface 1131 includes a first dyeing box receiving end M1 and a first dyeing box pushing end M2 that are arranged along an extending direction D1 of the first guiding surface 1131.
In practical applications, the first dyeing section R2 and the second dyeing section R4 in the above another embodiment, or the first dyeing section R2 and the second dyeing box transmission section R32 in the above another embodiment are generally horizontally disposed, that is, the heights of the second dyeing box receiving end and the second dyeing box pushing end in the vertical direction Z are the same, therefore, in this embodiment, the first guiding surface 1131 is disposed in an inclined manner with respect to the horizontal direction X, so that the height of the first dyeing box receiving end M1 in the vertical direction Z is smaller than that of the second dyeing box pushing end, and the height of the first dyeing box pushing end M2 in the vertical direction Z is larger than that of the second dyeing box receiving end.
Further, the bearing mechanism 112 is disposed on the first guiding surface 1131, so that when the first driving mechanism 111 drives the bearing mechanism 112 to move, the bearing mechanism 112 moves from the first dyeing box receiving end M1 to the first dyeing box pushing end M2 along the extending direction C1 of the first guiding surface 1131.
Optionally, a slide rail 1132 is disposed on the first guide surface 1131, an extending direction of the slide rail 1132 is the same as an extending direction of the first guide surface 1131, and the bearing mechanism 112 is mounted on the slide rail 1132 and moves along the slide rail 1132.
Further referring to fig. 1, the first transmission unit 11 of the present embodiment further includes a pushing mechanism 114, the pushing mechanism 114 includes a first power element 1141 and a pushing member 1142, the pushing member 1142 is connected to the first power element 1141, the first power element 1141 is configured to drive the pushing member 1142 to push the dye cartridge 120 out of the first dye cartridge push-out end M1, for example, the first power element 1141 of the slide receiving area R1 pushes the dye cartridge 120 out of the first dye region R2, or the first power element 1141 of the dye cartridge transmission area R3 pushes the dye cartridge 120 out of the second dye region R4.
Referring to fig. 9, fig. 9 is a schematic perspective view of another embodiment of the first transmission unit 11 in fig. 1, where the first transmission unit 11 in the another embodiment includes a first driving mechanism 11a, a bracket 11b and a carrying mechanism 11c, where the first driving mechanism 11a is the same as the first driving mechanism 111 in the above embodiment, and is not described herein again.
Referring to fig. 10 and 11 together, fig. 10 is a front view of an embodiment of the bracket 11b in fig. 9, fig. 11 is a front view of another embodiment of the bracket 11b in fig. 9, in which the bracket 11b includes a first guide surface 111a and a second guide surface 111b, the first guide surface 111a includes a first dyeing box receiving end M1 and a first dyeing box pushing end M2 and is disposed in an inclined manner with respect to a horizontal direction, and the second guide surface 111b is disposed opposite to the first guide surface 111a to form a guide channel 111c.
Alternatively, as shown in fig. 10, in an embodiment, the second guiding surface 111b is disposed parallel to the first guiding surface 111a, that is, the extending direction D2 of the second guiding surface 111b is the same as the extending direction D1 of the first guiding surface 111a, and both are disposed obliquely with respect to the horizontal direction, so that the width H of the guiding channel 111c in the direction from the first dyeing box receiving end M1 to the first dyeing box pushing end M2 is the same, that is, the distance between the second guiding surface 111b and the first guiding surface 111a is kept constant in the direction from the first dyeing box receiving end M1 to the first dyeing box pushing end M2.
Alternatively, as shown in fig. 11, in another embodiment, the extending direction D2 of the second guiding surface 111b is disposed to intersect with the extending direction D1 of the first guiding surface 111a, that is, the second guiding surface 111b is disposed to be non-parallel to the first guiding surface 111a, for example, the extending direction D1 of the first guiding surface 111a is disposed to be inclined with respect to the horizontal direction, and the extending direction D2 of the second guiding surface 111b is the same as the horizontal direction, so that the width H of the guiding channel 111c gradually increases from the first dyeing box receiving end M1 to the first dyeing box pushing end M2.
Referring to fig. 9, 12 and 13 together, fig. 12 is a schematic perspective view of the carrying mechanism 11c in fig. 9, fig. 13 is a schematic front view of the carrying mechanism 11c in fig. 12 and the bracket 12a in fig. 11 assembled together, the carrying mechanism 11c is disposed in cooperation with the guiding channel 111c, so that when the carrying mechanism 11c reciprocates between the first dyeing box receiving end M1 and the first dyeing box pushing end M2, the stability of the carrying mechanism 11c in the motion process is increased through the guiding channel 111c.
The bearing mechanism 11c includes a base 112a and a supporting component 112b for bearing the dyeing box 120, the base 112a is attached to the second guiding surface 111b and connected to the first driving mechanism 11a, the supporting component 112b is attached to the first guiding surface 111a and slidably connected to the base 112a, an elastic component 112c is disposed between the supporting component 112b and the base 112a, and the elastic component 112c is respectively abutted to the supporting component 112b and the base 112a, so that the bearing mechanism 11c can always keep being matched with the guiding channel 111c when moving, that is, the supporting component 112b can always be attached to the first guiding surface 111a, and the base 112a can always be attached to the second guiding surface 111b.
Further, the supporting component 112b comprises a supporting member 1121a and a rolling member 1121b, the supporting member 1121a is slidably connected with the base 112a, and the rolling member 1121b is rotatably connected with the supporting member 1121a and is attached to the first guiding surface 111a, so that when the carrying mechanism 11c reciprocates in a direction from the first dyeing box receiving end M1 to the first dyeing box pushing end M2, friction generated between the rolling member 1121b and the first guiding surface 111a is rolling friction, and resistance of the first guiding surface 111a to the carrying mechanism 11c in the motion process is reduced. Referring to fig. 10 or fig. 11, a receiving positioning slot 111d and a pushing positioning slot 111e are disposed on a side of the bracket 11b close to the first guiding surface 111a, and the rolling member 1121b is disposed at the receiving end M1 of the first dyeing box and the pushing end M2 of the first dyeing box and is respectively matched with the receiving positioning slot 111d and the pushing positioning slot 111e, so as to improve the position accuracy of the dyeing box 120 when receiving the slide 110 and pushing the dyeing box 120.
Referring to fig. 14, fig. 14 is a perspective view of the second transmission unit 12 provided in the present application, in which the second transmission unit 12 in the present embodiment includes a second motor 121, a second driving wheel 122, a plurality of second driven wheels 123 and a second transmission belt 124, the second driving wheel 122 is connected to an output shaft of the second motor 121, and the second transmission belt 124 is respectively wound around the second driving wheel 122 and the plurality of second driven wheels 123, so that the second motor 121 transmits the dyeing box 120 through the second transmission belt 124.
Further, the second conveying unit 12 further includes a second tensioning wheel 125, and the second tensioning wheel 125 is pressed on the second conveying belt 124 to increase the tensioning degree of the second conveying belt 124.
Referring to fig. 1, 15 and 16 together, fig. 15 is a schematic perspective view of an embodiment of the positioning mechanism 14 in fig. 1, fig. 16 is a schematic perspective view of the staining cassette 120 in fig. 1, the staining apparatus 10 in this embodiment further includes a liquid injection mechanism 13, the liquid injection mechanism 13 is configured to inject a staining reagent into the staining cassette 120 in the first staining region R2, so that the slide 110 is stained in the first staining region R2, it can be understood that, when the staining apparatus 10 further includes the second staining region R4 as in the above another embodiment, the liquid injection mechanism 13 also injects the staining reagent into the staining cassette 120 in the second staining region R4.
Wherein, the number of the liquid injection mechanism 13 is the same as the number of the types of the staining reagents, for example, when the blood cell sample is coated on the slide 110, the staining procedure of the blood cell sample specifically comprises: the cell is fixed, the first dyeing, the second dyeing, the first cleaning, the third dyeing, the second cleaning and the drying, therefore, the dyeing reagent includes a fixing solution, a first dyeing solution, a first mixed solution formed by mixing the first dyeing solution and a buffer solution, a first cleaning solution, a second mixed solution formed by mixing the second dyeing solution and the buffer solution and a second cleaning solution which respectively correspond to the processes, namely, the liquid injection mechanism 13 needs to sequentially inject six dyeing reagents into the dyeing box 120, therefore, the number of the liquid injection mechanisms 13 is also six, different dyeing reagents are injected into the dyeing box 120 by different liquid injection mechanisms 13, and the cross contamination is avoided. In another embodiment, the number of the liquid injection mechanisms 13 may be different from the number of the types of the staining reagents, for example, the number of needles in the liquid injection mechanism is increased so that the number of the liquid injection mechanisms is smaller than the number of the staining reagents. It is understood that the number of the liquid injection mechanisms 13 and the number of the types of the staining reagents may be the same or different according to the design, and are not limited herein.
Further, the staining cassette 120 is provided with a second support part 120a, and a liquid injection groove 120b and a staining groove 120c that are communicated with each other are formed, and the second support part 120a is mounted on the support mechanism 112. In the present embodiment, the second support part 120a is mounted in the support groove 1123, the slide 110 is inserted into the staining groove 120c, and the liquid injection mechanism 13 injects the staining reagent into the liquid injection groove 120b, so that the staining reagent flows into the staining groove 120c to stain the slide 110, and this arrangement can prevent the liquid injection mechanism 13 from colliding with the slide 110 during liquid injection and damaging the liquid injection mechanism 13 or the slide.
The liquid injection mechanism 13 includes a second power element 131, a liquid injection pipe 132, a liquid discharge pipe 133, and a cleaning pipe 134, and the second power element 131 is respectively communicated with the liquid injection pipe 132, the liquid discharge pipe 133, and the cleaning pipe 134, so as to sequentially inject the dyeing reagent into the dyeing box 120, discharge the dyeing reagent, and clean the dyeing box 120 through the liquid injection pipe 132, the liquid discharge pipe 133, and the cleaning pipe 134.
Further, the dyeing apparatus 10 in the present embodiment further includes a positioning mechanism 14, and the positioning mechanism 14 includes a first power unit 141, a stopper 142, and a positioning unit 143.
Wherein, the stopper 142 is connected with the first power unit 141, so that the first power unit 141 drives the stopper 142 to move to the conveying path of the staining box 120.
Specifically, after the second transmission unit 12 of the first dyeing region R2 and/or the second dyeing region R4 receives the dyeing cassette 120 loaded with the slide 110, the dyeing cassette 120 is transported by the second transmission unit 12 to be in a moving state, and when the liquid injection mechanism 13 injects the dye solution into the dyeing cassette 120, the dyeing cassette 120 needs to stop moving.
Alternatively, in the present embodiment, the first power unit 141 drives the stopper 142 to move onto the conveying path of the staining cassette 120 in the vertical direction Z.
Alternatively, the first power unit 141 is a screw motor, but in other embodiments, the first power unit 141 may also be another power unit, such as an air cylinder.
Further, the staining box 120 is provided with a first positioning portion 1201, optionally, the first positioning portion 1201 is a positioning groove, and in other embodiments, the first positioning portion 1201 may also be a positioning protrusion.
The first positioning portion 1201 is disposed on one side of the staining box 120 facing the opening direction of the staining bath 120 c.
Optionally, in this embodiment, the number of the first positioning portions 1201 is two, one of the first positioning portions 1201 is a circular groove, and the other one is a strip-shaped groove, and the two first positioning portions 1201 are respectively disposed on two opposite sides of the dyeing bath 120 c.
Referring to fig. 17, fig. 17 is an enlarged schematic view of a portion E in fig. 15, the positioning unit 143 is provided with a second positioning portion 143a, and the second positioning portion 143a is configured to cooperate with the first positioning portion 1201, so that the dye box 120 is positioned by the first positioning portion 1201 and the second positioning portion 143a, the position accuracy of the dye box 120 is improved, and the liquid injection stability of the liquid injection mechanism 13 is further improved.
Optionally, the second positioning portion 143a is a positioning protrusion engaged with the positioning groove, and in other embodiments, the second positioning portion 143a may also be a positioning groove.
In the present embodiment, the positioning unit 143 is connected to the stopper 142, so that the first power unit 141 drives the positioning unit 143 to approach the dyeing cassette 120, so that the positioning protrusion of the second positioning portion 143a is inserted into the positioning groove of the first positioning portion 1201.
Specifically, when the first power unit 141 drives the stopper 142 to move, the stopper 142 stops the dyeing box 120, and the dyeing box 120 stops moving, at this time, the first power unit 141 continues to drive the stopper 142 to move, and the positioning unit 143 connected to the stopper 142 continues to move along with the stopper 142 until the positioning protrusion of the second positioning portion 143a is inserted into the positioning groove of the first positioning portion 1201, so as to complete the positioning of the dyeing box 120.
Furthermore, the end of the second positioning portion 143a is provided with an inclined guiding surface 1431, and the positioning protrusion of the second positioning portion 143a is inserted into the positioning groove of the first positioning portion 1201 under the guiding action of the inclined guiding surface 1431, so as to improve the accuracy of inserting the positioning protrusion into the positioning groove.
In the present embodiment, the number of the positioning units 143 is two, and the two positioning units 143 can position three positions of the dye cartridge 120 with the stoppers 142, thereby improving the positioning accuracy of the dye cartridge 120.
Further, the stopper 142 includes a stopper body 1421 and a connecting body 1422, the stopper body 1421 is connected to the first power unit 141 to stop the dyeing box 120 under the driving of the first power unit 141, the connecting body 1422 is connected to the stopper body 1421 in a bending manner, and the positioning unit 143 is installed on the connecting body 1422.
Wherein, in this embodiment, the number of connecting body 1422 is two, and two locating unit 143 are installed respectively on two connecting body 1422, and two connecting body 1422 intervals set up to make form between two locating unit 143 and annotate the liquid space, thereby make annotate liquid mechanism 13 and can inject the dyeing reagent into dyeing box 120 through this annotate liquid space.
Furthermore, the positioning mechanism 14 further comprises a bracket 144, and the first power unit 141 and the liquid injection mechanism 13 are both mounted on the bracket 144, so that the first power unit 141 and the liquid injection mechanism 13 share one bracket 144, the occupied space of the positioning mechanism 14 and the liquid injection mechanism 13 is reduced, and the layout rationality of the device is improved.
Referring to fig. 18, fig. 18 is a schematic perspective view of another embodiment of the positioning mechanism 14 in fig. 1, in which the positioning mechanism 14 in the another embodiment includes a first power unit 14a, a stopping member 14b, a positioning unit 14c and a second power unit 14d, where the first power unit 14a, the stopping member 14b and the positioning unit 14c are respectively the same as the first power unit 141, the stopping member 142 and the positioning unit 143 in the above embodiment, and are not described again.
The second power unit 14d is used for driving the positioning unit 14c to approach the dyeing box 120, so that the second positioning portion 143a and the first positioning portion 1201 are cooperatively disposed.
Further, the positioning unit 14c is movably connected to the stopper 14b, the second power unit 14d includes a power element 140a and a pushing assembly 140b, the power element 140a is connected to the pushing assembly 140b to drive the pushing assembly 140b to push the positioning unit 14c to move relative to the stopper 14b, so that the second positioning portion 143a is disposed in cooperation with the first positioning portion 1201 during the movement of the positioning unit 14c relative to the stopper 14 b.
In this embodiment, the positioning unit 14c is rotatably connected to the stop member 14b, so that when the positioning unit 14c rotates relative to the stop member 14b, the second positioning portion 143a is disposed in cooperation with the first positioning portion 1201, for example, the second positioning portion 143a is a positioning protrusion, the first positioning portion 1201 is a positioning groove, and when the positioning unit 14c rotates relative to the stop member 14b, the positioning protrusion is inserted into the positioning groove, so that not only the dye cartridges 120 can be positioned, but also the dye cartridges 120 can be shifted by the positioning protrusion during the insertion of the positioning protrusion into the positioning groove, so that the position of the dye cartridges 120 is changed under the shifting action of the positioning protrusion.
It will be appreciated that in other embodiments, the positioning unit 14c and the stop member 14b may be movably connected, such as slidably connected.
Referring to fig. 19 and 20 together, fig. 19 is a schematic view illustrating a state where the positioning unit 14c in fig. 18 is separated from the positioning, fig. 20 is a schematic view illustrating a positioning state of the positioning unit 14c in fig. 18, the positioning mechanism 14 in this embodiment further includes an elastic restoring member 14e, the elastic restoring member 14e is respectively connected to the stopper 12b and the positioning unit 14c, when the second power unit 14d pushes the positioning unit 14c to rotate from the initial state shown in fig. 19 to a state where the second positioning portion 143a shown in fig. 20 is engaged with the first positioning portion 1201, the positioning unit 14c rotates in the direction K1, and during the rotation, the positioning unit 14c needs to overcome the elastic force of the elastic restoring member 14e, so that when the second power unit 14d is far away from the positioning unit 14c, the positioning unit 14c rotates in the direction K2 under the elastic force of the elastic restoring member 14e, and thus rotates from the engaged state shown in fig. 20 to the initial state shown in fig. 19, that is the positioning unit 14c is separated from the positioning box 14c, and thus the positioning unit 14c can continuously perform multiple cycles of the positioning.
Referring to fig. 18, the pushing assembly 140b in this embodiment includes a connecting member 1401 and a pushing member 1402, the connecting member 1401 is fixedly connected to the power element 140a, and the pushing member 1402 is rotatably connected to the connecting member 1401, so that when the power element 140a drives the pushing assembly 140b to push the positioning unit 14c to rotate, the pushing member 1402 rotates relative to the connecting member 1401, the resistance between the pushing member 1402 and the positioning unit 14c is reduced, and the operation reliability of the mechanism is improved.
Referring to fig. 21 and 22 together, fig. 21 is a schematic perspective view of an embodiment of a push piece dyeing machine 20 provided in the present application, and fig. 22 is a schematic block diagram of the push piece dyeing machine 20 in fig. 21, wherein the push piece dyeing machine 20 in the present embodiment includes a push piece device 21 and a dyeing device 10 in the above embodiment.
The slide pusher 21 is used to apply the specimen to the slide 110, and then the staining apparatus 10 stains the slide 110.
Further, the slide-pushing dyeing machine 20 in this embodiment further includes a controller 22, the controller 22 is configured to control the first transmission unit 11 of the slide receiving area R1 to transmit the dyeing cassette 120 after receiving the slide 110 to the first dyeing area R2, the second transmission unit 12 of the first dyeing area R2 to transmit the dyeing cassette 120 to the first dyeing box transmission area R3, the first transmission unit 11 of the dyeing box transmission area R3 to transmit the dyeing cassette 120 to the slide receiving area R1, and the controller 22 is further configured to control the first power unit to drive the stop member to move on the transmission path of the dyeing cassette, and the second positioning portion of the positioning unit is configured to cooperate with the first positioning portion.
Referring to fig. 23, fig. 23 is a schematic flow chart of an embodiment of a dyeing method provided in the present application, in which the dyeing method includes:
s1: the first transmission unit of the slide receiving area receives the slide and transmits the staining box after receiving the slide to the first staining area;
s2: staining the slide in a first staining area;
s3: the second transmission unit of the first dyeing area transmits the dyeing box to the dyeing box transmission area;
s4: a first transport unit of the staining cassette transport zone transports the staining cassette to the slide receiving zone.
It is understood that the specific working principle of the above steps can refer to the embodiment of the dyeing apparatus 10, and will not be described herein.
Different from the situation of the prior art, the dyeing device provided by the embodiment of the application comprises a slide receiving area, a first dyeing area and a dyeing box transmission area which are sequentially connected end to end, wherein the slide receiving area and the dyeing box transmission area are respectively provided with a first transmission unit, and the first dyeing area is provided with a second transmission unit; wherein, the first transmission unit in slide receiving area is used for carrying the dyeing box after receiving the slide to first dyeing district, the second transmission unit in first dyeing district is used for carrying the dyeing box to dyeing box transmission area, the first transmission unit in dyeing box transmission area is used for carrying the dyeing box to the slide receiving area, make to dye the box and can reuse, do not need manual operation, degree of automation is high, whole device cloth is reasonable, the space utilization of instrument is high, and compare in the mode of disc conveying, the transmission quantity of dyeing box has been improved, the efficiency of dyeing is improved.
The above description is only a part of the embodiments of the present application, and not intended to limit the scope of the present application, and all equivalent devices or equivalent processes, which are directly or indirectly applied to other related technical fields, and are made by using the contents of the specification and the drawings of the present application, are also included in the scope of the present application.

Claims (12)

1. A positioning mechanism, characterized in that the positioning mechanism comprises:
a first power unit;
the stopping piece is connected with the first power unit, so that the first power unit drives the stopping piece to move to a conveying path of a dyeing box, and the dyeing box is provided with a first positioning part;
and the positioning unit is provided with a second positioning part which is used for being matched with the first positioning part.
2. The positioning mechanism according to claim 1, further comprising a second power unit for driving the positioning unit close to the staining cassette.
3. The positioning mechanism of claim 2 wherein the positioning unit is movably coupled to the stop member, and the second power unit includes a power element and a pushing assembly, the power element being coupled to the pushing assembly to drive the pushing assembly to move the positioning unit relative to the stop member.
4. The positioning mechanism of claim 3 wherein the positioning unit is rotatably coupled to the stop.
5. The positioning mechanism according to claim 4, further comprising an elastic restoring member, wherein the elastic restoring member is connected to the stop member and the positioning unit, respectively.
6. The positioning mechanism of claim 4, wherein the pushing assembly comprises a connecting member and a pushing member, the connecting member is fixedly connected with the power element, and the pushing member is rotatably connected with the connecting member.
7. The positioning mechanism of claim 1, further comprising a bracket, wherein the first power unit is mounted on the bracket, and the bracket is further provided with a liquid injection mechanism for injecting a dyeing reagent into the dyeing box.
8. The positioning mechanism according to claim 7, wherein the dyeing box is formed with a dyeing tank, the first positioning portion is disposed on a side of the dyeing box facing an opening direction of the dyeing tank, the stopper comprises a stopper body and a connecting body, the stopper body is connected to the first power unit, the connecting body is connected to the stopper body in a bent manner, and the positioning unit is mounted on the connecting body.
9. The positioning mechanism according to claim 8, wherein the number of the first positioning portions is two, two first positioning portions are respectively disposed on two opposite sides of the dyeing bath, the number of the connecting bodies and the number of the positioning units are two, two connecting bodies are spaced apart from each other, and two positioning units are respectively mounted on the two connecting bodies to form the liquid injection space.
10. A staining apparatus, comprising a transport unit and the positioning mechanism of any one of claims 1 to 9, wherein the transport unit is configured to transport the staining cassette such that the slides in the staining cassette are stained on the transport unit.
11. A push slide staining machine comprising a push device for applying a sample onto said slide and a staining apparatus as recited in claim 10.
12. Push-piece dying machine according to claim 11, characterised in that it further comprises a controller for controlling the first power unit to drive the stop element to move onto the delivery path of the dying cartridge, respectively, the second positioning portion of the positioning unit being arranged in cooperation with the first positioning portion.
CN202110877372.2A 2021-07-31 2021-07-31 Position adjusting mechanism, dyeing device and push sheet dyeing machine Pending CN115683792A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110877372.2A CN115683792A (en) 2021-07-31 2021-07-31 Position adjusting mechanism, dyeing device and push sheet dyeing machine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110877372.2A CN115683792A (en) 2021-07-31 2021-07-31 Position adjusting mechanism, dyeing device and push sheet dyeing machine

Publications (1)

Publication Number Publication Date
CN115683792A true CN115683792A (en) 2023-02-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110877372.2A Pending CN115683792A (en) 2021-07-31 2021-07-31 Position adjusting mechanism, dyeing device and push sheet dyeing machine

Country Status (1)

Country Link
CN (1) CN115683792A (en)

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