CN115624609A - 一种治疗急慢性气管炎的中药制剂及其制备方法 - Google Patents
一种治疗急慢性气管炎的中药制剂及其制备方法 Download PDFInfo
- Publication number
- CN115624609A CN115624609A CN202211273368.6A CN202211273368A CN115624609A CN 115624609 A CN115624609 A CN 115624609A CN 202211273368 A CN202211273368 A CN 202211273368A CN 115624609 A CN115624609 A CN 115624609A
- Authority
- CN
- China
- Prior art keywords
- ginger
- preparation
- traditional chinese
- medicine
- lung
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 77
- 206010044302 Tracheitis Diseases 0.000 title claims abstract description 45
- 238000002360 preparation method Methods 0.000 title claims abstract description 43
- 230000001154 acute effect Effects 0.000 title claims abstract description 21
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 48
- 235000008397 ginger Nutrition 0.000 claims abstract description 48
- 238000005303 weighing Methods 0.000 claims abstract description 16
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 14
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 14
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 14
- 241000218671 Ephedra Species 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims abstract description 12
- 238000001035 drying Methods 0.000 claims abstract description 7
- 241001289295 Asarum sieboldii Species 0.000 claims abstract description 4
- 241001106477 Paeoniaceae Species 0.000 claims abstract 5
- 241000234314 Zingiber Species 0.000 claims description 46
- 239000007788 liquid Substances 0.000 claims description 35
- 241000931705 Cicada Species 0.000 claims description 25
- 238000009835 boiling Methods 0.000 claims description 23
- 229940079593 drug Drugs 0.000 claims description 22
- 244000183685 Citrus aurantium Species 0.000 claims description 18
- 235000007716 Citrus aurantium Nutrition 0.000 claims description 18
- 235000002789 Panax ginseng Nutrition 0.000 claims description 18
- 238000001816 cooling Methods 0.000 claims description 18
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 15
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 15
- 239000003651 drinking water Substances 0.000 claims description 14
- 235000020188 drinking water Nutrition 0.000 claims description 14
- 239000002184 metal Substances 0.000 claims description 14
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 13
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 13
- 235000011477 liquorice Nutrition 0.000 claims description 13
- 241000490229 Eucephalus Species 0.000 claims description 12
- 235000014676 Phragmites communis Nutrition 0.000 claims description 10
- 238000001914 filtration Methods 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 238000002791 soaking Methods 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 6
- 241001522129 Pinellia Species 0.000 claims description 5
- 240000006079 Schisandra chinensis Species 0.000 claims description 5
- 238000011049 filling Methods 0.000 claims description 5
- 235000012907 honey Nutrition 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 230000001376 precipitating effect Effects 0.000 claims description 5
- 241000758794 Asarum Species 0.000 claims description 4
- 235000017965 Asarum canadense Nutrition 0.000 claims description 4
- 235000000385 Costus speciosus Nutrition 0.000 claims description 4
- 241000606265 Valeriana jatamansi Species 0.000 claims description 4
- 235000014687 Zingiber zerumbet Nutrition 0.000 claims description 4
- 235000013399 edible fruits Nutrition 0.000 claims description 4
- 239000008187 granular material Substances 0.000 claims description 4
- 210000004072 lung Anatomy 0.000 abstract description 59
- 206010011224 Cough Diseases 0.000 abstract description 47
- 210000002216 heart Anatomy 0.000 abstract description 13
- 208000006673 asthma Diseases 0.000 abstract description 9
- 230000001737 promoting effect Effects 0.000 abstract description 7
- 206010014561 Emphysema Diseases 0.000 abstract description 6
- 210000003437 trachea Anatomy 0.000 abstract description 5
- 201000006306 Cor pulmonale Diseases 0.000 abstract description 4
- 208000004186 Pulmonary Heart Disease Diseases 0.000 abstract description 4
- 230000017531 blood circulation Effects 0.000 abstract description 4
- 210000005259 peripheral blood Anatomy 0.000 abstract description 4
- 239000011886 peripheral blood Substances 0.000 abstract description 4
- 230000001105 regulatory effect Effects 0.000 abstract description 4
- 230000002040 relaxant effect Effects 0.000 abstract description 4
- 210000002460 smooth muscle Anatomy 0.000 abstract description 4
- 206010035664 Pneumonia Diseases 0.000 abstract description 3
- 210000004404 adrenal cortex Anatomy 0.000 abstract description 3
- 210000000621 bronchi Anatomy 0.000 abstract description 3
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 2
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 208000037656 Respiratory Sounds Diseases 0.000 abstract description 2
- 206010047924 Wheezing Diseases 0.000 abstract description 2
- 244000273928 Zingiber officinale Species 0.000 abstract description 2
- 210000004100 adrenal gland Anatomy 0.000 abstract description 2
- 208000026935 allergic disease Diseases 0.000 abstract description 2
- 230000000172 allergic effect Effects 0.000 abstract description 2
- 230000007815 allergy Effects 0.000 abstract description 2
- 208000010668 atopic eczema Diseases 0.000 abstract description 2
- 210000004204 blood vessel Anatomy 0.000 abstract description 2
- 230000001684 chronic effect Effects 0.000 abstract description 2
- 210000003743 erythrocyte Anatomy 0.000 abstract description 2
- 230000034659 glycolysis Effects 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 230000000414 obstructive effect Effects 0.000 abstract description 2
- 230000000144 pharmacologic effect Effects 0.000 abstract description 2
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 24
- 208000026435 phlegm Diseases 0.000 description 24
- 210000000952 spleen Anatomy 0.000 description 13
- 239000006187 pill Substances 0.000 description 12
- 244000170916 Paeonia officinalis Species 0.000 description 9
- 230000001717 pathogenic effect Effects 0.000 description 9
- 210000002784 stomach Anatomy 0.000 description 9
- 210000003734 kidney Anatomy 0.000 description 8
- 238000010792 warming Methods 0.000 description 8
- 206010013975 Dyspnoeas Diseases 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 208000000059 Dyspnea Diseases 0.000 description 6
- 206010047700 Vomiting Diseases 0.000 description 6
- 235000009508 confectionery Nutrition 0.000 description 6
- 208000011580 syndromic disease Diseases 0.000 description 6
- 230000008673 vomiting Effects 0.000 description 6
- 206010037660 Pyrexia Diseases 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 5
- 230000033001 locomotion Effects 0.000 description 5
- 210000004243 sweat Anatomy 0.000 description 5
- 206010019233 Headaches Diseases 0.000 description 4
- 206010061245 Internal injury Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 208000005392 Spasm Diseases 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 231100000869 headache Toxicity 0.000 description 4
- 235000008216 herbs Nutrition 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- 235000014347 soups Nutrition 0.000 description 4
- 206010063659 Aversion Diseases 0.000 description 3
- 208000008454 Hyperhidrosis Diseases 0.000 description 3
- 206010028748 Nasal obstruction Diseases 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- 230000001914 calming effect Effects 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 230000002354 daily effect Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 230000001939 inductive effect Effects 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 2
- 241000287828 Gallus gallus Species 0.000 description 2
- 235000017443 Hedysarum boreale Nutrition 0.000 description 2
- 235000007858 Hedysarum occidentale Nutrition 0.000 description 2
- 208000019693 Lung disease Diseases 0.000 description 2
- 230000001174 ascending effect Effects 0.000 description 2
- 206010006451 bronchitis Diseases 0.000 description 2
- 208000023819 chronic asthma Diseases 0.000 description 2
- 208000013116 chronic cough Diseases 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 description 2
- 230000009545 invasion Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 230000002936 tranquilizing effect Effects 0.000 description 2
- 208000037911 visceral disease Diseases 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000331983 Arisaema consanguineum Species 0.000 description 1
- 241000132092 Aster Species 0.000 description 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 235000008422 Schisandra chinensis Nutrition 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000001780 adrenocortical effect Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 201000009267 bronchiectasis Diseases 0.000 description 1
- 230000002612 cardiopulmonary effect Effects 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 230000037315 hyperhidrosis Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 230000005980 lung dysfunction Effects 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Insects & Arthropods (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Physiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明属于中医药领域，尤其是一种治疗急慢性气管炎的中药制剂及其制备方法，其中药制剂包括以下重量份的原料：麻黄10‑450g、桂枝10‑450g、赤芍10‑450g、辽细辛10‑400g，制备方法包括以下步骤：S1、将中药材除生姜外其余干燥净化，按最佳质量配比称量备用；本发明具有驰缓气管、支气管平滑肌的作用，有扩张外周血管，改善肾上腺皮质功能及心肺功能，降低血流阻力，改善血液循环，促进红细胞糖酵解等药理作用，具有止咳平喘、抗炎、抗敏，调节血管及肾上腺、肺功能等作用，为临床治疗急慢性气管炎、肺炎、肺气肿、肺心病、慢阻师、过敏性气管炎引起的吼咳喘、提供了药理学依据。
Description
技术领域
本发明涉及中医药领域，尤其涉及一种治疗急慢性气管炎的中药制剂及其制备方法。
背景技术
吼、咳、喘是肺系疾患的主要症状之一，常见于上呼吸道感染、气管炎、支气管炎、肺炎、支气管扩张、慢性支气管炎、肺气肿、肺心病、慢阻肺等疾病中。本病的发生多因外邪侵袭、肺卫受邪、肺气不得宣畅而引起吼、咳、喘等症，也有因其它脏腑病变影响到肺的宣发和肃降功能而出现以上症状者。如脾虚生湿聚痰上犯于肺，或肝气郁而化火，气火上乘于肺均可发生以上症状。如张景岳说：“咳证虽多，无非肺病”。喻嘉言也认为：“咳者肺之本病也”。《医学三字经·咳嗽第四》；“《内经》云：五脏六腑皆能令人咳，非独肺也。”然肺为气之主，诸气上逆于肺，则呛而咳，是咳嗽不止于肺，而亦不离乎肺也。《活法机要》“咳谓无痰而有声，肺气伤而不清也。嗽谓无声而有痰，脾湿动而生痰也，咳嗽是有声有痰，因伤肺气复动脾湿也”。肺系为气体升降出入之通道，肺为华蓋,外邪侵袭首当其冲，肺叉为娇脏，只受轻清之气,受不得秽浊之气,而且最易被风寒、风热、燥热等外邪所伤。
综上所述，肺功能失调是吼、咳、喘发生的关键所在，不论外感或其它脏腑疾病，均能累及肺脏，导致吼、咳、喘等症。由于感受外邪引起的咳嗽，为外感咳嗽；由于脏腑功能失调引起的咳嗽，称为内伤咳嗽。外感咳嗽久治不愈，可发展为内伤咳嗽。内伤咳嗽患者往往体虚，营卫不固，易被外邪所伤，使咳嗽加剧。内伤咳嗽反复发作，可使肺、心、脾、肾俱虚，影响气血之运行，津液之输布而成为严重病症。如肺气肿、肺心病、慢阻肺、肺痨、哮症及喘症。肺脏受邪，痰气交阻，气道阻塞不利而出现喉痒咳嗽、呼吸时咽喉和气管间发出声响,如水鸡声如拽锯声谓之气吼；呼吸迫促，张口抬肩，心累气短，甚则摇身撷肚，不能平卧谓之咳喘。
现有的中药剂不具有驰缓气管、支气管平滑肌的作用，无法有效的扩张外周血管，无法改善肾上腺皮质功能及心肺功能。
发明内容
本发明的目的是为了解决现有技术中存在中药剂不具有驰缓气管、支气管平滑肌的作用，无法有效的扩张外周血管，无法改善肾上腺皮质功能及心肺功能的缺点，而提出的一种治疗急慢性气管炎的中药制剂及其制备方法。
本发明提出的一种治疗急慢性气管炎的中药制剂，包括以下重量份的原料：麻黄10-20g、桂枝10-20g、赤芍10-20g、辽细辛10-20g、干姜10-20g、法半夏15-30g、北五味子10-20g、红参10-20g、蝉蜕10-20g、紫苑10-20g、芦根10-20g、枳实10-20g、生姜10-20g、甘草10-20g。
优选的，包括以下重量份的原料：麻黄20-45g、桂枝20-45g、赤芍20-45g、辽细辛20-40g、干姜20-35g、法半夏30-50g、北五味子20-40g、红参20-45g、蝉蜕15-30g、紫苑20-45g、芦根20-45g、枳实20-45g、生姜15-35g、甘草20-35g。
优选的，包括以下重量份的原料：麻黄450g、桂枝450g、赤芍450g、辽细辛400g、干姜350g、法半夏500g、北五味子400g、红参450g、蝉蜕300g、紫苑450g、芦根450g、枳实450g、生姜350g、甘草350g。
本发明还提出了一种治疗急慢性气管炎的中药制剂的制备方法，包括以下步骤：
S1、将中药材除生姜外其余干燥净化，按最佳质量配比称量备用；
S2、将红参切片，生姜切片，甘草蜜炙，枳实麸炒至微黄；
S3、将按最佳质量配比称重，并依法炮制后的药物，除生姜、蝉蜕外，其余药品全部破碎为颗粒备用；
S4、将破碎后的药物和生姜、蝉蜕全部装入金属容器内，加入五倍量的饮用水，即29kg，在10-25℃常温下浸泡8h，每隔1-2h搅拌一次；
S5、将浸泡8h后的汤药搅拌，加热煮沸后，小火慢煮30-40分钟后，降温过滤出药汁，装入金属容器中备用；
S6、将过滤后的药渣加饮用水8kg，煮沸后小火煮30-40分钟后，降温过滤出药汁，加入第一次煮出的药液内合匀，称重备用；
S7、将两次煮出的药汁，小火煮沸浓缩至二分之一后，降温沉淀,吸出清液,按口服液的制备方法，制备为口服液；
S8、将口服液分装于药用塑料刻度瓶中，每刻度为10ml，每200ml为一瓶，每10瓶为一盒。
优选的，所述S1中，最佳质量配比为：以下共5800g，计5.8kg：麻黄450g、桂枝450g、赤芍450g、辽细辛400g、干姜350g、法半夏500g、北五味子400g、红参450g、蝉蜕300g、紫苑450g、芦根450g、枳实450g、生姜350g、甘草350g。
优选的，所述S4中，将破碎后的药物和生姜、蝉蜕全部装入金属容器内，加入五倍量的饮用水，即29kg，在25℃常温下浸泡8h，每隔2h搅拌一次。
优选的，所述S5中，将浸泡8h后的汤药搅拌，加热煮沸后，小火慢煮30分钟后，降温过滤出药汁，装入金属容器中备用。
优选的，所述S6中，将过滤后的药渣加饮用水8kg，煮沸后小火煮30分钟后，降温过滤出药汁，加入第一次煮出的药液内合匀，称重备用。
麻黄：归肺、膀胱经，具有发汗平喘利水之作用，用于外感风寒，恶寒发热，头身疼痛，鼻塞无汗的表寒实证。
桂枝：归心、肺、膀胱经，具有发汗解表，温经通阳之作用，用于外感风寒之头痛、发热、恶寒等证，常与药物配伍调和营卫，与麻黄配伍助其发汗解表作用，两者常相须为用。
赤芍：苦、微寒，归肝经，具有清热凉血，祛瘀缓急止痛之作用。
辽细辛：辛温，归肺、肾经，具有祛风散寒、止痛、温肺化饮、宣通鼻窍等作用。
本品芳香气浓，性善走窜，常用于寒饮伏肺，咳嗽气喘，痰多清稀者，具温肺化饮开闭之功,是治疗肺气闭阻而咳喘的主药，常与麻黄、干姜、北五味子配伍应用。同时亦治鼻炎、鼻塞、流清涕、头痛等证。
干姜：辛热，归脾、胃、心、肺经。具有温中、回阳、温肺化饮之功，用于寒饮伏肺、咳嗽气喘、痰多清稀、形寒背冷等证，常与麻黄、细辛、北五味子同用。
法半夏：辛温，归脾、胃、肺经，具有燥湿化痰，降逆止呕，消痞散结之功，用于脾不化湿，痰涎壅滞所致的痰多、咳嗽、气逆、胸脘痞闷，呕吐等证，是治湿痰之要药，常配伍细辛、干姜同用。
北五味子：酸、温，归肺、肾、心经。具有敛肺滋肾，生津敛汗、宁心安神等作用，常用于久咳虚喘，肺肾不足之喘咳，具有止咳平喘、宁心安神之效。
红参：甘、微苦，微温，入心、肺、脾经，元气下起于肾，上及于肺，为人体生化动力之源泉。本品擅大补元气，脾为生化之源，肺为主气之脏，元气旺盛则脾肺肾元气充足，免疫力増强病体易于康复，故本品为补心,肺、脾,肾气之主药。
蝉蜕：甘、寒，归肺、肝经。具有疏风热、透疹，息风止痉，明目退翳之功效，并有凉散风热，清利头目，治疗风热郁肺，发热、咽痛、声音嘶哑，开宣肺气之效，具有抗过敏作用，解麻黄容易引起呕吐之弊。
紫苑：苦、甘、微、温，归肺经，具有化痰止咳，用于咳嗽气逆，咯痰不爽，其性温润苦泄，有较好的化痰止咳作用，常用于外感风寒，咳嗽痰多，以及肺虚久咳，痰中带血等多种类型的咳嗽。
芦根：甘、寒，归肺、胃经，具有清热生津，止呕除烦。用于肺热咳嗽，痰稠口干，能清泄肺热，疏畅气管，润燥缓咳，常用于肺痈咳吐脓痰。
枳实：苦、辛，微寒，归肺、胃、大肠经，具有行气消积，化痰除痞之效，常用于食积停滞，脘腹胀满，痰浊阻塞气机，有行气消痰，理气通痞塞,升举中气之功。
生姜：辛，微温，归肺、胃经，具有发汗解表，温中止呕，温肺止咳等功效，用于外感风寒，恶寒发热，头痛、鼻塞，能温中和胃，降逆止呕，能解半夏、南星、鱼蟹之毒。
甘草：甘、平，归心、肺、脾、胃经；具有补脾益气，润肺止咳，缓急止痛，缓和药性之功效。
采用麻黄、桂枝、细辛、法半夏、干姜发汗解表，温散肺寒，化痰饮，祛伏邪.利肺气，为君药；红参补肺、脾、肾之气，赤芍、五味子、紫苑、蝉蜕、芦根宣通气管、支气管，解痉化痰，止咳喘，为臣药；枳实、芦根调畅气机，治胸脘痞胀，为佐药；生姜、甘草辛散甘甜，入脾肺，为使药。
本发明的有益效果是：
本发明具有驰缓气管、支气管平滑肌的作用，有扩张外周血管，改善肾上腺皮质功能及心肺功能，降低血流阻力，改善血液循环，促进红细胞糖酵解等药理作用，具有止咳平喘、抗炎、抗敏，调节血管及肾上腺、肺功能等作用，为临床治疗急慢性气管炎、肺炎、肺气肿、肺心病、慢阻师、过敏性气管炎引起的吼咳喘、提供了药理学依据。
具体实施方式
下面结合具体实施例对本发明作进一步解说。
实施例一
本发明提出了一种治疗急慢性气管炎的中药制剂，包括以下重量份的原料：包括以下重量份的原料：麻黄10g、桂枝10g、赤芍10g、辽细辛10g、干姜10g、法半夏15g、北五味子10g、红参10g、蝉蜕10g、紫苑10g、芦根10g、枳实10g、生姜10g、甘草10g；
其制备方法包括以下步骤：
S1、将中药材除生姜外其余干燥净化，按配比称量备用；
S2、将红参切片，生姜切片，甘草蜜炙，枳实麸炒至微黄；
S3、按配比称重，并依法炮制后的药物，除生姜、蝉蜕外，其余药品全部破碎为颗粒备用；
S4、将破碎后的药物和生姜、蝉蜕全部装入金属容器内，加入五倍量的饮用水，即29kg，在10℃常温下浸泡8h，每隔1h搅拌一次；
S5、将浸泡8h后的汤药搅拌，加热煮沸后，小火慢煮30分钟后，降温过滤出药汁，装入金属容器中备用；
S6、将过滤后的药渣加饮用水8kg，煮沸后小火煮30分钟后，降温过滤出药汁，加入第一次煮出的药液内合匀，称重备用；
S7、将两次煮出的药汁，小火煮沸浓缩至二分之一后，降温沉淀,吸出清液,按口服液的制备方法，制备为口服液；
S8、将口服液分装于药用塑料刻度瓶中，每刻度为10ml，每200ml为一瓶，每10瓶为一盒。
服用方法：1-2岁小儿，每次服20ml，每天服3次；2-4岁小儿，每次服30ml，每天服3次；4-6岁小儿，每次服40ml，每日服3次；6-8岁儿童，每次服50ml，每天服3次；8-10岁儿童，每次服60ml，每天服3次；10-12岁儿童，每次服70ml，每日服3次；12-14岁儿童，每次服80ml，每日服3次；14-16岁儿童，每次服80-90ml，每日服3次；16-18岁少年，改服浓缩丸。
实施例二
本发明提出了一种治疗急慢性气管炎的中药制剂，包括以下重量份的原料：包括以下重量份的原料：麻黄45g、桂枝45g、赤芍45g、辽细辛40g、干姜35g、法半夏50g、北五味子40g、红参45g、蝉蜕30g、紫苑45g、芦根45g、枳实45g、生姜35g、甘草35g；
其制备方法包括以下步骤：
S1、将中药材除生姜外其余干燥净化，按配比称量备用；
S2、将红参切片，生姜切片，甘草蜜炙，枳实麸炒至微黄；
S3、按配比称重，并依法炮制后的药物，除生姜、蝉蜕外，其余药品全部破碎为颗粒备用；
S4、将破碎后的药物和生姜、蝉蜕全部装入金属容器内，加入五倍量的饮用水，即29kg，在15℃常温下浸泡8h，每隔2h搅拌一次；
S5、将浸泡8h后的汤药搅拌，加热煮沸后，小火慢煮35分钟后，降温过滤出药汁，装入金属容器中备用；
S6、将过滤后的药渣加饮用水8kg，煮沸后小火煮35分钟后，降温过滤出药汁，加入第一次煮出的药液内合匀，称重备用；
S7、将两次煮出的药汁，小火煮沸浓缩至二分之一后，降温沉淀,吸出清液,按口服液的制备方法，制备为口服液；
S8、将口服液分装于药用塑料刻度瓶中，每刻度为10ml，每200ml为一瓶，每10瓶为一盒。
实施例三
本发明提出了一种治疗急慢性气管炎的中药制剂，包括以下重量份的原料：麻黄450g、桂枝450g、赤芍450g、辽细辛400g、干姜350g、法半夏500g、北五味子400g、红参450g、蝉蜕300g、紫苑450g、芦根450g、枳实450g、生姜350g、甘草350g；
其制备方法包括以下步骤：
S1、将中药材除生姜外其余干燥净化，按配比称量备用；
S2、将红参切片，生姜切片，甘草蜜炙，枳实麸炒至微黄；
S3、按配比称重，并依法炮制后的药物，除生姜、蝉蜕外，其余药品全部破碎为颗粒备用；
S4、将破碎后的药物和生姜、蝉蜕全部装入金属容器内，加入五倍量的饮用水，即29kg，在25℃常温下浸泡8h，每隔2h搅拌一次；
S5、将浸泡8h后的汤药搅拌，加热煮沸后，小火慢煮30分钟后，降温过滤出药汁，装入金属容器中备用；
S6、将过滤后的药渣加饮用水8kg，煮沸后小火煮30分钟后，降温过滤出药汁，加入第一次煮出的药液内合匀，称重备用；
S7、将两次煮出的药汁，小火煮沸浓缩至二分之一后，降温沉淀,吸出清液,按口服液的制备方法，制备为口服液；
S8、将口服液分装于药用塑料刻度瓶中，每刻度为10ml，每200ml为一瓶，每10瓶为一盒。
实施例四
与实施例一的区别在于：S7中，将两次煮出的药汁，加热浓缩后，按浓缩丸的制备方法制备为浓缩丸，每10丸重5g，每100丸为一瓶，每10瓶为一盒，每10丸相当于配方饮片30g药效；
服用方法：
16-18岁少年，每次服12丸，每天服3次；18岁以上成人，每次服15丸，每天服3次。病情严重者，每次服18丸，每天服3次。
禁忌：
1、肺胃有热患者，出现烦燥，发热，多汗，口渴，舌红胎黄，尿少便秘者，禁用此口服液和浓缩丸。
2、患者禁食酸、冷、油腻食物。
对实施例一至四制得的治疗急慢性气管炎的中药制剂，对比常规的中药制剂，实验数据如下表所示：
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。
Claims (8)
1.一种治疗急慢性气管炎的中药制剂，其特征在于，包括以下重量份的原料：麻黄10-450g、桂枝10-450g、赤芍10-450g、辽细辛10-400g、干姜10-350g、法半夏15-500g、北五味子10-400g、红参10-450g、蝉蜕10-300g、紫苑10-450g、芦根10-450g、枳实10-450g、生姜10-350g、甘草10-350g。
2.根据权利要求1所述的一种治疗急慢性气管炎的中药制剂，其特征在于，包括以下重量份的原料：麻黄20-45g、桂枝20-45g、赤芍20-45g、辽细辛20-40g、干姜20-35g、法半夏30-50g、北五味子20-40g、红参20-45g、蝉蜕15-30g、紫苑20-45g、芦根20-45g、枳实20-45g、生姜15-35g、甘草20-35g。
3.根据权利要求1所述的一种治疗急慢性气管炎的中药制剂，其特征在于，包括以下重量份的原料：麻黄450g、桂枝450g、赤芍450g、辽细辛400g、干姜350g、法半夏500g、北五味子400g、红参450g、蝉蜕300g、紫苑450g、芦根450g、枳实450g、生姜350g、甘草350g。
4.一种治疗急慢性气管炎的中药制剂的制备方法，其特征在于，包括以下步骤：
S1、将中药材除生姜外其余干燥净化，按最佳质量配比称量备用；
S2、将红参切片，生姜切片，甘草蜜炙，枳实麸炒至微黄；
S3、将按最佳质量配比称重，并依法炮制后的药物，除生姜、蝉蜕外，其余药品全部破碎为颗粒备用；
S4、将破碎后的药物和生姜、蝉蜕全部装入金属容器内，加入五倍量的饮用水，即29kg，在10-25℃常温下浸泡8h，每隔1-2h搅拌一次；
S5、将浸泡8h后的汤药搅拌，加热煮沸后，小火慢煮30-40分钟后，降温过滤出药汁，装入金属容器中备用；
S6、将过滤后的药渣加饮用水8kg，煮沸后小火煮30-40分钟后，降温过滤出药汁，加入第一次煮出的药液内合匀，称重备用；
S7、将两次煮出的药汁，小火煮沸浓缩至二分之一后，降温沉淀,吸出清液,按口服液的制备方法，制备为口服液；
S8、将口服液分装于药用塑料刻度瓶中，每刻度为10ml，每200ml为一瓶，每10瓶为一盒。
5.根据权利要求4所述的一种治疗急慢性气管炎的中药制剂的制备方法，其特征在于，所述S1中，最佳质量配比为：以下共5800g，计5.8kg：麻黄450g、桂枝450g、赤芍450g、辽细辛400g、干姜350g、法半夏500g、北五味子400g、红参450g、蝉蜕300g、紫苑450g、芦根450g、枳实450g、生姜350g、甘草350g。
6.根据权利要求4所述的一种治疗急慢性气管炎的中药制剂的制备方法，其特征在于，所述S4中，将破碎后的药物和生姜、蝉蜕全部装入金属容器内，加入五倍量的饮用水，即29kg，在25℃常温下浸泡8h，每隔2h搅拌一次。
7.根据权利要求4所述的一种治疗急慢性气管炎的中药制剂的制备方法，其特征在于，所述S5中，将浸泡8h后的汤药搅拌，加热煮沸后，小火慢煮30分钟后，降温过滤出药汁，装入金属容器中备用。
8.根据权利要求4所述的一种治疗急慢性气管炎的中药制剂的制备方法，其特征在于，所述S6中，将过滤后的药渣加饮用水8kg，煮沸后小火煮30分钟后，降温过滤出药汁，加入第一次煮出的药液内合匀，称重备用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211273368.6A CN115624609A (zh) | 2022-10-18 | 2022-10-18 | 一种治疗急慢性气管炎的中药制剂及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211273368.6A CN115624609A (zh) | 2022-10-18 | 2022-10-18 | 一种治疗急慢性气管炎的中药制剂及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115624609A true CN115624609A (zh) | 2023-01-20 |
Family
ID=84907193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211273368.6A Pending CN115624609A (zh) | 2022-10-18 | 2022-10-18 | 一种治疗急慢性气管炎的中药制剂及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115624609A (zh) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101856488A (zh) * | 2009-04-09 | 2010-10-13 | 刘君峰 | 用于治疗气管炎的中药 |
| CN102309593A (zh) * | 2011-06-16 | 2012-01-11 | 廖天源 | 一种治疗湿疹的药物及其制备方法 |
| CN104623555A (zh) * | 2015-02-15 | 2015-05-20 | 山东省千佛山医院 | 一种治疗急性喘息性支气管炎的中药制剂及制备方法 |
| CN107537012A (zh) * | 2016-06-28 | 2018-01-05 | 郝纪涛 | 一种疏风清热的中药方 |
-
2022
- 2022-10-18 CN CN202211273368.6A patent/CN115624609A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101856488A (zh) * | 2009-04-09 | 2010-10-13 | 刘君峰 | 用于治疗气管炎的中药 |
| CN102309593A (zh) * | 2011-06-16 | 2012-01-11 | 廖天源 | 一种治疗湿疹的药物及其制备方法 |
| CN104623555A (zh) * | 2015-02-15 | 2015-05-20 | 山东省千佛山医院 | 一种治疗急性喘息性支气管炎的中药制剂及制备方法 |
| CN107537012A (zh) * | 2016-06-28 | 2018-01-05 | 郝纪涛 | 一种疏风清热的中药方 |
Non-Patent Citations (2)
| Title |
|---|
| 张雪云: "小青龙汤加味治疗急、慢性支气管炎140例疗效观察", 河北中医, vol. 24, no. 12, pages 1 * |
| 王莉: "小青龙汤治疗小儿咳嗽40例疗效观察", 云南中医中药杂志, vol. 26, no. 05, pages 16 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103463609B (zh) | 治疗上呼吸道感染的中药口服汤剂中成药的制备方法 | |
| CN102293975B (zh) | 一种治疗肺结核的药物及其制备方法 | |
| CN103142950A (zh) | 一种治疗婴儿腹泻的中药 | |
| CN104825778A (zh) | 一种用于治疗犊牛肺炎的中药组合物 | |
| CN104001045A (zh) | 一种用于治疗犬肺炎的药物及其制备方法 | |
| CN102580003B (zh) | 一种治疗小儿哮喘的中药口服液及制备方法 | |
| CN104706976A (zh) | 一种治疗失眠的益气安神中药剂及制备方法 | |
| CN104027540A (zh) | 一种治寒痰阻肺证型哮喘的中药 | |
| CN100353985C (zh) | 止咳喘与润肺的药物及其制备方法 | |
| CN103211964A (zh) | 一种治疗咳嗽的中药 | |
| CN115624609A (zh) | 一种治疗急慢性气管炎的中药制剂及其制备方法 | |
| CN104707010A (zh) | 一种治疗肺炎的清热解毒中药组合物及制备方法 | |
| CN104857404A (zh) | 治疗百日咳的化痰止咳中药制剂 | |
| CN104721767A (zh) | 一种治疗小儿咳嗽的中药组合物及其制备方法 | |
| CN1338268A (zh) | 止咳喘润肺膏及其制作方法 | |
| CN109370855A (zh) | 一种具有改善脾胃、减轻腹部隐痛和改善睡眠功能的保健酒及其制备方法 | |
| CN109486628A (zh) | 一种具有增强免疫力、缓解疲劳和改善睡眠功能的保健酒及其制备方法 | |
| CN108619472A (zh) | 一种治疗支气管炎的食疗配方及其制备方法 | |
| CN102430074B (zh) | 一种治疗慢性支气管炎的中药组合物 | |
| CN106110156A (zh) | 一种用于慢性阻塞性肺疾病的膏方、制备方法及其用途 | |
| CN105853720A (zh) | 一种根治慢性支气管炎的药物及制备方法 | |
| CN104784566A (zh) | 一种治疗儿童呼吸道感染的中药 | |
| CN105832873A (zh) | 一种润肺、止咳的牛大力组合物及其制备方法和应用 | |
| CN105232919A (zh) | 一种治疗小儿支气管肺炎中药组合物及其制备方法 | |
| CN104784487A (zh) | 一种用于治疗肺栓塞的中药制剂及制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20230120 |
|
| RJ01 | Rejection of invention patent application after publication |