CN115554189B - Hand cream containing schizophyllum commune extracellular crude polysaccharide and preparation method thereof - Google Patents
Hand cream containing schizophyllum commune extracellular crude polysaccharide and preparation method thereof Download PDFInfo
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- CN115554189B CN115554189B CN202211252092.3A CN202211252092A CN115554189B CN 115554189 B CN115554189 B CN 115554189B CN 202211252092 A CN202211252092 A CN 202211252092A CN 115554189 B CN115554189 B CN 115554189B
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- 229920001282 polysaccharide Polymers 0.000 title claims abstract description 51
- 239000005017 polysaccharide Substances 0.000 title claims abstract description 51
- 150000004676 glycans Chemical class 0.000 title claims abstract description 50
- 239000008269 hand cream Substances 0.000 title claims abstract description 47
- 241000222481 Schizophyllum commune Species 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 33
- 241000222480 Schizophyllum Species 0.000 claims abstract description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 27
- 239000012153 distilled water Substances 0.000 claims abstract description 12
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000004166 Lanolin Substances 0.000 claims abstract description 11
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims abstract description 11
- 235000021355 Stearic acid Nutrition 0.000 claims abstract description 11
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229940075529 glyceryl stearate Drugs 0.000 claims abstract description 11
- 229940039717 lanolin Drugs 0.000 claims abstract description 11
- 235000019388 lanolin Nutrition 0.000 claims abstract description 11
- 229940057995 liquid paraffin Drugs 0.000 claims abstract description 11
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims abstract description 11
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000008117 stearic acid Substances 0.000 claims abstract description 11
- 229940099259 vaseline Drugs 0.000 claims abstract description 11
- 229960004274 stearic acid Drugs 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 7
- 238000005303 weighing Methods 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 4
- 229960004418 trolamine Drugs 0.000 claims description 3
- 230000003020 moisturizing effect Effects 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 8
- 230000032683 aging Effects 0.000 abstract description 6
- 230000009286 beneficial effect Effects 0.000 abstract description 6
- 230000003647 oxidation Effects 0.000 abstract description 6
- 238000007254 oxidation reaction Methods 0.000 abstract description 6
- 230000032677 cell aging Effects 0.000 abstract description 3
- 235000016709 nutrition Nutrition 0.000 abstract description 3
- 230000035764 nutrition Effects 0.000 abstract description 3
- 238000001035 drying Methods 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 15
- 230000000052 comparative effect Effects 0.000 description 11
- 229920002305 Schizophyllan Polymers 0.000 description 9
- WDQLRUYAYXDIFW-RWKIJVEZSA-N (2r,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-4-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O1 WDQLRUYAYXDIFW-RWKIJVEZSA-N 0.000 description 8
- 230000014759 maintenance of location Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000001732 sebaceous gland Anatomy 0.000 description 2
- 210000002374 sebum Anatomy 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241000222479 Schizophyllaceae Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- -1 schizophyllan polysaccharide Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a hand cream containing schizophyllum commune extracellular crude polysaccharide and a preparation method thereof, wherein the hand cream comprises the following components in percentage by mass: 4.30% of glyceryl stearate, 8.61% of stearic acid, 5.74% of lanolin, 10.05% of vaseline, 7.18% of liquid paraffin, 3.83% of triethanolamine, 10.53% of glycerol, 0.96% of sodium dodecyl sulfate, 3.83% of schizophyllum extracellular crude polysaccharide and 44.97% of distilled water; and provides a specific preparation method thereof. The hand cream prepared by the invention takes the schizophyllum extracellular crude polysaccharide as a main nutrition component, so that the hand cream with good moisturizing property and oxidation resistance is obtained, the prepared hand cream is safe and easy to absorb, and the hand cream is beneficial to delaying cell aging and reducing hand fine wrinkles while locking skin moisture and moistening and drying rough hands, so that the effect of resisting hand aging is achieved; in addition, the hand cream prepared by the invention is free from adding pungent components, and has higher safety.
Description
Technical Field
The invention relates to the technical field of skin care product preparation, in particular to a hand cream containing schizophyllum commune extracellular crude polysaccharide and a preparation method thereof.
Background
The Schizophyllum commune (Schizophyllum commune Fr.) is fungus of Schizophyllum genus of Schizophyllaceae family. The fruiting body is small, covered with tile-shaped scattered or clustered, fan-shaped or kidney-shaped, without handle or short handle, covered with dense fluff and white to light gray; the inner edge of the cover is curled, and has stripes and multiple petals, and the bacterial folds are narrow and are rolled back outwards along the longitudinal cracks of the folds. The schizophyllum commune is widely distributed in various places in China, contains various active ingredients such as schizophyllum commune polysaccharide, schizophyllum commune, sterol and the like, and has remarkable medicinal value. The schizophyllum commune can obtain crude extracellular polysaccharide of the schizophyllum commune through the steps of fermentation, filtration, concentration, alcohol precipitation and the like. The schizophyllum extracellular polysaccharide is nonionic water-soluble polysaccharide, and the mild and non-irritating polyhydroxy structure of the schizophyllum extracellular polysaccharide can keep moisture and lock water, so that the moisture content of the skin cuticle is maintained, and the schizophyllum extracellular polysaccharide can be used as a humectant in the preparation of hand cream; according to researches, the schizophyllan extracellular polysaccharide also has the effect of improving the cell immunity, enhances the capability of cell proliferation reaction of mice, has a certain effect of delaying aging, and also discloses the effect of delaying aging in the paper "research progress of schizophyllan and schizophyllan polysaccharide" of Min Dexin published in 2014.
Sebaceous glands are the sites where skin synthesizes and secretes sebum, and sebum not only lubricates skin, but also plays a role in moisturizing as a skin barrier, but the hand does not have sebaceous glands, so the hand skin is particularly dry in autumn and winter. In daily life, hands inevitably contact with cleaning products such as detergents and facial washes, and the main cleaning components in the cleaning products such as surfactants and soap bases remove hand grease, so that the hands feel dry and the hand skin is easy to age. Based on this, it is highly desirable for those skilled in the art to provide a hand cream with good moisturizing effect and oxidation resistance.
Disclosure of Invention
Aiming at the problems, the invention provides a hand cream containing schizophyllum commune extracellular crude polysaccharide and a preparation method thereof. Solves the problems of dry hand skin and easy aging in the prior art.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows:
the invention discloses a hand cream containing schizophyllum commune extracellular crude polysaccharide, which comprises the following components in percentage by mass: 4.23 to 4.48 percent of glyceryl stearate, 8.45 to 8.95 percent of stearic acid, 5.63 to 5.97 percent of lanolin, 9.86 to 10.45 percent of Vaseline, 7.04 to 7.46 percent of liquid paraffin, 3.76 to 3.98 percent of triethanolamine, 10.33 to 10.94 percent of glycerol, 0.94 to 1.00 percent of sodium dodecyl sulfate, 0 to 5.63 percent of schizophyllan extracellular crude polysaccharide and 44.13 to 46.77 percent of distilled water.
Further, the composition comprises the following components in percentage by mass: 4.30% of glyceryl stearate, 8.61% of stearic acid, 5.74% of lanolin, 10.05% of vaseline, 7.18% of liquid paraffin, 3.83% of triethanolamine, 10.53% of glycerol, 0.96% of sodium dodecyl sulfate, 3.83% of schizophyllan extracellular crude polysaccharide and 44.97% of distilled water.
A preparation method of a hand cream containing schizophyllum commune extracellular crude polysaccharide specifically comprises the following steps:
s1: weighing glyceryl stearate, stearic acid, lanolin, vaseline, liquid paraffin and triethanolamine according to mass percentage, mixing, and heating in water bath for heat preservation to obtain phase A;
s2: weighing glycerol, sodium dodecyl sulfate, schizophyllum extracellular crude polysaccharide and distilled water according to mass percentage, mixing, and heating and preserving heat in a water bath to obtain a phase B;
s3: slowly adding phase A into phase B, continuously stirring for 5min, taking out the mixture from the water bath, and continuously stirring until light yellow semisolid paste is formed.
Further, the water bath heating temperature in the step S1 is 80.8 ℃.
Further, the water bath heating temperature in the step S2 is 80.8 ℃.
Further, the temperature of the A, B phase in the step S3 is 80.8 ℃.
Compared with the prior art, the invention has the beneficial effects that:
according to the hand cream containing the schizophyllum extracellular crude polysaccharide, provided by the invention, the hand cream with good hygroscopicity, moisture retention and oxidation resistance is obtained by adding the schizophyllum extracellular crude polysaccharide into the hand cream, and various beneficial biological activities of the schizophyllum extracellular crude polysaccharide are utilized. The hand cream disclosed by the invention takes the schizophyllum extracellular crude polysaccharide as a main nutrition component, and the prepared hand cream is safe and easy to absorb, and can lock skin moisture and moisten dry and rough hands; the oxidation resistance of the schizophyllum extracellular polysaccharide is beneficial to delaying cell aging, reducing the generation of hand fine lines and playing a role in resisting hand aging; the hand cream prepared by the invention has no pungent component, high safety and can be used by non-sensitive people with safety.
Detailed Description
The present invention will be described in further detail with reference to examples in order to make the objects and advantages of the present invention more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
The instruments, reagents, materials, etc. used in the following examples are conventional instruments, reagents, materials, etc. known in the art, and are commercially available. The experimental methods, detection methods, and the like in the following examples are conventional experimental methods, detection methods, and the like existing in the prior art unless otherwise specified.
Example 1
The hand cream containing schizophyllum extracellular crude polysaccharide comprises the following components in percentage by mass: 4.30% of glyceryl stearate, 8.61% of stearic acid, 5.74% of lanolin, 10.05% of vaseline, 7.18% of liquid paraffin, 3.83% of triethanolamine, 10.53% of glycerol, 0.96% of sodium dodecyl sulfate, 3.83% of schizophyllan extracellular crude polysaccharide and 44.97% of distilled water.
The preparation method of the hand cream containing schizophyllum commune extracellular crude polysaccharide comprises the following steps:
s1: weighing glyceryl stearate, stearic acid, lanolin, vaseline, liquid paraffin and triethanolamine according to mass percentage, mixing, and heating in water bath at 80.8deg.C to obtain phase A;
s2: weighing glycerol, sodium dodecyl sulfate, crude schizophyllum extracellular polysaccharide and distilled water according to the mass percentage, mixing the components, and then placing the components in a water bath at 80.8 ℃ for water bath heating and heat preservation to obtain phase B;
s3: continuously and slowly adding the phase A with the temperature of 80.8 ℃ into the phase B with the temperature of 80.8 ℃, continuously stirring for 5min, taking the mixture out of the water bath kettle, and continuously stirring until a light yellow semi-solid paste is formed, thus obtaining the hand cream.
Comparative example 1
The hand cream containing schizophyllum extracellular crude polysaccharide comprises the following components in percentage by mass: 4.48% of glyceryl stearate, 8.95% of stearic acid, 5.97% of lanolin, 10.45% of Vaseline, 7.46% of liquid paraffin, 3.98% of triethanolamine, 10.94% of glycerol, 1.00% of sodium dodecyl sulfate, 0% of schizophyllan extracellular crude polysaccharide and 46.77% of distilled water.
The preparation method is the same as in example 1.
Comparative example 2
The hand cream containing schizophyllum extracellular crude polysaccharide comprises the following components in percentage by mass: 4.23% of glyceryl stearate, 8.45% of stearic acid, 5.63% of lanolin, 9.86% of vaseline, 7.04% of liquid paraffin, 3.76% of triethanolamine, 10.33% of glycerol, 0.94% of sodium dodecyl sulfate, 5.63% of schizophyllan extracellular crude polysaccharide and 44.13% of distilled water.
The preparation method is the same as in example 1.
Comparative example 3
The hand cream containing schizophyllum extracellular crude polysaccharide comprises the following components in percentage by mass: 4.39% of glyceryl stearate, 8.78% of stearic acid, 5.85% of lanolin, 10.25% of vaseline, 7.32% of liquid paraffin, 3.90% of triethanolamine, 10.73% of glycerol, 0.98% of sodium dodecyl sulfate, 1.95% of schizophyllan extracellular crude polysaccharide and 45.85% of distilled water.
The preparation method is the same as in example 1.
The hand creams of example 1 and comparative examples 1 to 3 containing crude schizophyllum extracellular polysaccharide were respectively subjected to the following tests for moisturizing properties: respectively weighing 2g of sample and 1g of distilled water, uniformly mixing, placing in a dryer filled with dry silica gel at room temperature (27+/-1), respectively measuring the water mass (m 1, m 2) before and after the sample is placed through 4h, 8h, 12h and 24h, respectively testing 3 times, calculating the moisture retention rate, and taking the average value: moisture retention (%) =100% m2/m1. The test results are shown in Table 1 below:
TABLE 1
From table 1 above, it is clear that the hand cream containing crude schizophyllum extracellular polysaccharide prepared in this example 1 has good moisturizing efficiency, the moisturizing rate can reach 97.3% after 8 hours, the moisturizing rate can still reach 95.3% after 12 hours, and the moisturizing rate can still reach more than 74.67% after 24 hours, thus the hand cream has good moisturizing performance.
The hand creams prepared in example 1 and comparative examples 1 to 3 containing crude schizophyllum extracellular polysaccharide were respectively subjected to efficacy tests, which were carried out by the following methods: 100 subjects were selected, women aged 18-40 in the same area were randomly divided into four groups, and each group of subjects was respectively coated with the schizophyllum commune extracellular crude polysaccharide hand cream prepared in example 1 and comparative examples 1-3 in an environment with a test environment temperature of 27 ℃ and a relative humidity of 71%, and after 2 hours, the moisture, oil content and elasticity of the backs of the hands were tested. A square area of 1 x 2cm is drawn on the back of the hand, and a multifunctional skin tester (model RBX-916) is used as a test area of the sample to test the moisture, oil content and elasticity of the skin of the hand. The multifunctional skin tester respectively measures the moisture, oil content and elasticity of the hand skin 2 hours before and after hand cream application, records the results, counts the average value and keeps two effective figures. The test results are shown in Table 2 below:
TABLE 2
As can be seen from the test data in table 2, the hand cream of the examples was used for two hours, in terms of moisture test: the moisture retention effect of example 1 was optimal; in the aspect of oil content testing, the oil content of the example 1 and the comparative example 3 is reduced to a larger extent and is better than that of the comparative example 1 and the comparative example 2, so that the absorption effect of the example 1 and the comparative example 3 is good and the moistening effect is excellent; in terms of skin elasticity test: the most improved elasticity value of example 1 indicates that example 1 has good skin rejuvenation effect.
The skin feel of the hand cream containing crude schizophyllum commune extracellular polysaccharide of example 1 and comparative examples 1 to 3 was evaluated, and the results are shown in table 3:
TABLE 3 Table 3
As can be seen from Table 3, the hand cream containing crude extracellular polysaccharide of Schizophyllum commune prepared by the method of this example has no addition of irritating components, no irritation, good extensibility, proper viscosity, no bubbles, no allergy, high safety, and no liability to people.
In addition, the sensory indexes of the hand cream prepared in the embodiment 1 are detected according to QB/T1857-2013, the physicochemical indexes are detected according to QB/T1857-2013, the hygiene indexes are detected according to a method prescribed by Wei Fajian [2002] 229, and the sensory indexes comprise appearance color, aroma, paste uniformity and fineness; the physicochemical indexes relate to PH, cold resistance, heat resistance and centrifugation test, wherein the PH value is between 4.0 and 8.5, the cold resistance needs to be kept at (-8+/-2) ℃ for 24 hours, no obvious character difference exists between the temperature after room temperature recovery and the temperature before test, the heat resistance needs to be kept at (40+1) ℃ for 24 hours, the oil-free water separation phenomenon needs to be avoided after room temperature recovery, and the centrifugation test needs to be met after centrifugation for 30 minutes at 2000r/min, and no layering phenomenon exists; the sanitation index relates to microorganism index and toxic substances, the total bacterial count (CFU/g) is less than 1000, and the evaluation and detection results are shown in table 4:
TABLE 4 Table 4
As can be seen from table 4 above, the hand cream containing crude extracellular polysaccharide of schizophyllum commune prepared by the method of this example is pale yellow, meets the requirements of specified color and aroma, and meets the requirements of relevant regulations on uniformity and fineness of the cream; the pH of the hand cream prepared by the embodiment is 7.1, the heat resistance, the cold resistance and the sanitation index of the hand cream accord with national regulations, and the microbial content of the hand cream is far lower than the national relevant standard.
In conclusion, the hand cream containing the schizophyllum extracellular crude polysaccharide, which is prepared by the invention, is prepared by adding the schizophyllum extracellular crude polysaccharide into the hand cream, so that the hand cream with good hygroscopicity, moisture retention and oxidation resistance is obtained, and various beneficial biological activities of the schizophyllum extracellular crude polysaccharide are utilized. The hand cream provided by the invention takes the schizophyllum extracellular crude polysaccharide as a main nutrition component, and the prepared hand cream is safe and easy to absorb, and has the characteristics of light weight, thinness and no false white while locking skin moisture and moistening dry and rough hands; the oxidation resistance of the schizophyllum extracellular polysaccharide is beneficial to delaying cell aging, reducing the generation of hand fine lines and playing a role in resisting hand aging; in addition, the hand cream prepared by the invention is free from adding pungent components, has high safety and can be used by non-sensitive people with safety.
The foregoing description of the preferred embodiments of the present invention is not intended to limit the scope of the present invention, but it should be understood that any modifications, equivalents, improvements, etc. within the spirit and principles of the present invention will fall within the scope of the present invention.
Claims (1)
1. A hand cream comprising crude extracellular polysaccharide of schizophyllum commune, characterized in that: the weight percentage of the components is as follows: 4.30% of glyceryl stearate, 8.61% of stearic acid, 5.74% of lanolin, 10.05% of vaseline, 7.18% of liquid paraffin, 3.83% of triethanolamine, 10.53% of glycerol, 0.96% of sodium dodecyl sulfate, 3.83% of schizophyllum extracellular crude polysaccharide and 44.97% of distilled water;
the hand cream containing schizophyllum extracellular crude polysaccharide is prepared by the following preparation method:
s1: weighing glyceryl stearate, stearic acid, lanolin, vaseline, liquid paraffin and triethanolamine according to mass percentage, mixing, heating in water bath at 80.8deg.C, and maintaining the temperature to obtain phase A;
s2: weighing glycerol, sodium dodecyl sulfate, schizophyllum extracellular crude polysaccharide and distilled water according to mass percentage, mixing, heating in water bath at 80.8 ℃ and preserving heat to obtain phase B;
s3: continuously adding phase A to phase B at 80.8deg.C, continuously stirring for 5min, taking out the mixture from the water bath, and continuously stirring to form pale yellow semisolid paste.
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| KR20120037174A (en) * | 2010-10-11 | 2012-04-19 | (주)아이내추럴 | A skin-care agenton and production of exo-polysaccharide by submerged culture of novel schizophyllum commune sto516 kfcc 11489p |
| CN103767969A (en) * | 2014-01-14 | 2014-05-07 | 上海海洋大学 | Hand cream prepared from effective components in banana peels and preparation method of hand cream |
| CN104055700A (en) * | 2014-06-04 | 2014-09-24 | 上海欣富生物科技有限公司 | Anti-crack hand cream and preparation method thereof |
| CN112315846A (en) * | 2020-10-30 | 2021-02-05 | 广东丸美生物技术股份有限公司 | Schizophyllum commune polysaccharide liposome and preparation method and application thereof |
| JP2022073946A (en) * | 2020-10-30 | 2022-05-17 | 広東丸美生物技術股▲フン▼有限公司 | Schizophyllan liposome, and method for preparing and use of the same |
| CN114752504A (en) * | 2021-12-07 | 2022-07-15 | 云南白药集团上海科技有限公司 | Schizophyllum commune strain YSC1, intracellular and extracellular polysaccharide prepared based on the schizophyllum commune, cosmetics and preparation method |
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