CN115529815A - 经直肠施用的奥司他韦或其药学上可接受的盐的药物组合物、及其制备方法和用途 - Google Patents

经直肠施用的奥司他韦或其药学上可接受的盐的药物组合物、及其制备方法和用途 Download PDF

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Publication number
CN115529815A
CN115529815A CN202180003795.XA CN202180003795A CN115529815A CN 115529815 A CN115529815 A CN 115529815A CN 202180003795 A CN202180003795 A CN 202180003795A CN 115529815 A CN115529815 A CN 115529815A
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China
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weight
pharmaceutically acceptable
pharmaceutical composition
oseltamivir
acceptable salt
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CN202180003795.XA
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CN115529815B (zh
Inventor
陈燕娜
杨伟
彭军波
曾铭健
梁茜茜
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Guangzhou Gonghe Medicine Technology Co ltd
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Guangzhou Gonghe Medicine Technology Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Abstract

一种经直肠施用的奥司他韦或其药学上可接受的盐的药物组合物、及其制备方法和用途。该药物组合物包含奥司他韦或其药学上可接受的盐、适用于直肠施用的药学上可接受的半固体基质和任选的其他添加剂。该直肠施用的药物组合物用于预防和治疗流行性感冒。

Description

PCT国内申请，说明书已公开。

Claims (15)

  1. PCT国内申请，权利要求书已公开。
CN202180003795.XA 2021-04-27 2021-04-27 经直肠施用的奥司他韦或其药学上可接受的盐的药物组合物、及其制备方法和用途 Active CN115529815B (zh)

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PCT/CN2021/090233 WO2022226778A1 (zh) 2021-04-27 2021-04-27 经直肠施用的奥司他韦或其药学上可接受的盐的药物组合物、及其制备方法和用途

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CN115529815A true CN115529815A (zh) 2022-12-27
CN115529815B CN115529815B (zh) 2024-04-30

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CN (1) CN115529815B (zh)
WO (1) WO2022226778A1 (zh)

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09323933A (ja) * 1996-05-31 1997-12-16 Kanebo Ltd 安定性の改善された坐剤
WO2004014338A1 (en) * 2002-02-05 2004-02-19 Pharmacia & Upjohn Company Composition and method for rectal delivery of a lincosamide antibacterial drug
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US20090175805A1 (en) * 2006-03-13 2009-07-09 The Trustees Of Columbia University In The City Of New York Neuraminidase Inhibitors and uses thereof
CN102000341A (zh) * 2010-07-16 2011-04-06 钟术光 在栓剂组合物中的聚氧化乙烯及基质型表面活性剂
WO2012115945A1 (en) * 2011-02-21 2012-08-30 The Board Of Regents Of The University Of Texas System Viral inhibitors
CN104173338A (zh) * 2013-05-23 2014-12-03 天士力控股集团有限公司 一种治疗癌症用栓剂
CN105687205A (zh) * 2016-03-08 2016-06-22 中国医学科学院药用植物研究所 一种三萜类化合物的医药用途
US20170258749A1 (en) * 2014-12-01 2017-09-14 Lupin Atlantis Holdings Sa Oseltamivir Compositions
US20180200268A1 (en) * 2015-07-08 2018-07-19 Dr. Falk Pharma Gmbh Pharmaceutical formulation for the treatment of inflammatory changes to the rectum
WO2020093159A1 (en) * 2018-11-06 2020-05-14 Mcmaster University Broadly-neutralizing antibody and neuraminidase inhibitor combinations to prevent or treat influenza virus infections

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09323933A (ja) * 1996-05-31 1997-12-16 Kanebo Ltd 安定性の改善された坐剤
WO2004014338A1 (en) * 2002-02-05 2004-02-19 Pharmacia & Upjohn Company Composition and method for rectal delivery of a lincosamide antibacterial drug
CN1490016A (zh) * 2003-08-21 2004-04-21 武汉同药药业有限公司 一种用于治疗病毒性肝炎的栓剂及其制备方法
JP2005213177A (ja) * 2004-01-29 2005-08-11 Tendou Seiyaku Kk 安定な坐剤組成物および坐剤ならびにそれらの製造法
CN1582915A (zh) * 2004-05-28 2005-02-23 肖广常 一种新鱼腥草素钠栓剂
US20090175805A1 (en) * 2006-03-13 2009-07-09 The Trustees Of Columbia University In The City Of New York Neuraminidase Inhibitors and uses thereof
CN101278938A (zh) * 2008-03-20 2008-10-08 黑龙江加州国际投资咨询有限公司 泰诺福韦酯和恩替卡韦的复方制剂及其抗乙肝病毒的应用
CN102000341A (zh) * 2010-07-16 2011-04-06 钟术光 在栓剂组合物中的聚氧化乙烯及基质型表面活性剂
WO2012115945A1 (en) * 2011-02-21 2012-08-30 The Board Of Regents Of The University Of Texas System Viral inhibitors
CN104173338A (zh) * 2013-05-23 2014-12-03 天士力控股集团有限公司 一种治疗癌症用栓剂
US20170258749A1 (en) * 2014-12-01 2017-09-14 Lupin Atlantis Holdings Sa Oseltamivir Compositions
US20180200268A1 (en) * 2015-07-08 2018-07-19 Dr. Falk Pharma Gmbh Pharmaceutical formulation for the treatment of inflammatory changes to the rectum
CN105687205A (zh) * 2016-03-08 2016-06-22 中国医学科学院药用植物研究所 一种三萜类化合物的医药用途
WO2020093159A1 (en) * 2018-11-06 2020-05-14 Mcmaster University Broadly-neutralizing antibody and neuraminidase inhibitor combinations to prevent or treat influenza virus infections

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANTHONY S HAM等: "Designing and developing suppository formulations for anti-HIV drug delivery", 《THERAPEUTIC DELIVERY》, vol. 08, no. 09, pages 805 - 817 *
U WINTERGERST等: "Pharmacokinetics of zidovudine after rectal administration in human immunodeficiency virus-infected patients", 《ANTIMICROBIAL AGENTS AND CHEMOTHERAPY》, vol. 2007, no. 05, pages 1143 - 1145 *
牛莹等: "中药制剂常用辅料对神经氨酸酶活性的影响", 《药物生物技术》, vol. 23, no. 02, pages 129 - 133 *
罗志豪: "喷雾干燥制备口崩型复合辅料", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》, no. 2021, pages 076 - 32 *

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CN115529815B (zh) 2024-04-30
WO2022226778A1 (zh) 2022-11-03

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