CN115515955A - 4-[(7-氯-2-甲氧基苯并[b][1,5]萘啶-10-基)氨基]-2,6-双(吡咯烷-1-基甲基)苯酚及其盐的结晶形式 - Google Patents
4-[(7-氯-2-甲氧基苯并[b][1,5]萘啶-10-基)氨基]-2,6-双(吡咯烷-1-基甲基)苯酚及其盐的结晶形式 Download PDFInfo
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- CN115515955A CN115515955A CN202180028991.2A CN202180028991A CN115515955A CN 115515955 A CN115515955 A CN 115515955A CN 202180028991 A CN202180028991 A CN 202180028991A CN 115515955 A CN115515955 A CN 115515955A
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- powder
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- ylmethyl
- methoxybenzo
- naphthyridin
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| PCT/EP2021/059604 WO2021209477A1 (en) | 2020-04-17 | 2021-04-14 | Crystalline forms of 4-[(7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-2,6-bis(pyrrolidin-1-ylmethyl)phenol and salts thereof |
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| EP (1) | EP4136087A1 (https=) |
| JP (1) | JP2023522023A (https=) |
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| BR (1) | BR112022018436A2 (https=) |
| CA (1) | CA3175552A1 (https=) |
| PH (1) | PH12022552366A1 (https=) |
| WO (1) | WO2021209477A1 (https=) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101544638A (zh) * | 2009-05-12 | 2009-09-30 | 重庆通天药业有限公司 | 乳酸咯萘啶及其药物组合物 |
| KR20090114029A (ko) * | 2008-04-29 | 2009-11-03 | 강민석 | 피로나리딘의 제조방법 및 이를 위한 중간체 |
| CN103373995A (zh) * | 2012-04-28 | 2013-10-30 | 上海迪赛诺药业有限公司 | 一种制备咯萘啶的方法 |
| CN105461713A (zh) * | 2014-09-25 | 2016-04-06 | 刘力 | 苯并萘啶类的新化合物及其组合物和用途 |
| CN109843876A (zh) * | 2016-10-13 | 2019-06-04 | Mmv疟疾药物投资公司 | 新的抗疟剂 |
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| CA3182616A1 (en) * | 2020-06-15 | 2021-12-23 | Lukas Shinji OKITSU | Tlr7/8 antagonists and uses thereof |
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| WO2021209477A1 (en) | 2021-10-21 |
| JP2023522023A (ja) | 2023-05-26 |
| PH12022552366A1 (en) | 2024-03-18 |
| CA3175552A1 (en) | 2021-10-21 |
| BR112022018436A2 (pt) | 2022-11-01 |
| US20230295156A1 (en) | 2023-09-21 |
| EP4136087A1 (en) | 2023-02-22 |
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